amsacrine has been researched along with hydroxyurea in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Lihou, MG; Smith, PJ; Tomlinson, FH | 1 |
| Ferguson, LR | 1 |
| Estey, E; Silberman, L; Zwelling, LA | 1 |
| Andersson, HC; Kihlman, BA | 1 |
| Covey, JM; Holm, C; Kerrigan, D; Pommier, Y | 1 |
| Cordel, K; Holm, C; Vaughan, WP | 1 |
| Fernandes, DJ; Neff, TA; Paff, MT; Smith-Nanni, C | 1 |
| Haanen, C; Marie, JP; Marquet, J; Zittoun, J; Zittoun, R | 1 |
| Jehn, U; Löwenberg, B; Zittoun, R | 1 |
| Kerrigan, D; Minford, J; Nichols, M; Shackney, S; Zwelling, LA | 1 |
| Kreuzer, KN; Long, DT | 1 |
1 review(s) available for amsacrine and hydroxyurea
| Article | Year |
|---|---|
Intercalator-induced, topoisomerase II-mediated DNA cleavage and its modification by antineoplastic antimetabolites.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Azacitidine; Cell Survival; Cytarabine; DNA; DNA Topoisomerases, Type II; Drug Synergism; Humans; Hydroxyurea; In Vitro Techniques; Intercalating Agents; Mice | 1986 |
1 trial(s) available for amsacrine and hydroxyurea
| Article | Year |
|---|---|
[AML-6 and AML-7 studies on the treatment of acute myelocytic leukemia. Cyclic alternating chemotherapy during remission, and induction of remission and survival of elderly patients].
Topics: Adult; Age Factors; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azaguanine; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Vincristine | 1985 |
12 other study(ies) available for amsacrine and hydroxyurea
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of in vitro activity of epipodophyllotoxins with other chemotherapeutic agents in human medulloblastomas.
Topics: Alkylating Agents; Amsacrine; Cell Division; Cell Survival; Cross-Linking Reagents; Cytarabine; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Hydroxyurea; In Vitro Techniques; Karyotyping; Medulloblastoma; Teniposide; Tumor Cells, Cultured; Vincristine | 1991 |
Mutagenic and recombinogenic consequences of DNA-repair inhibition during treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea in Saccharomyces cerevisiae.
Topics: Amsacrine; Caffeine; Carmustine; Crossing Over, Genetic; DNA Repair; Hydroxyurea; Mutagenicity Tests; Mutation; Saccharomyces cerevisiae | 1990 |
The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II. I. m-AMSA.
Topics: Amsacrine; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes; Culture Media; Cytarabine; DNA Repair; Humans; Hydroxyurea; In Vitro Techniques; Lymphocytes; Sister Chromatid Exchange; Topoisomerase II Inhibitors; X-Rays | 1989 |
Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells.
Topics: Amsacrine; Animals; Aphidicolin; Camptothecin; Cell Line; Cell Survival; Cricetinae; Cricetulus; Diterpenes; DNA Replication; Etoposide; Hydroxyurea; Kinetics; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1989 |
Hydroxyurea potentiation of the antineoplastic activity of cyclophosphamide and 4'-(9-acridinylamino)methanesulfon-M-anisidide (AMSA) in the brown Norway rat myelocytic leukemia model.
Topics: Amsacrine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Hydroxyurea; Leukemia, Myeloid; Rats; Rats, Inbred BN | 1989 |
Effects of antileukemia agents on nuclear matrix-bound DNA replication in CCRF-CEM leukemia cells.
Topics: Amsacrine; Antineoplastic Agents; Cell Nucleus; Chromatin; Cytarabine; DNA Replication; Hydroxyurea; Microscopy, Electron; Nuclear Proteins; Teniposide; Tumor Cells, Cultured | 1988 |
Modulation of cytosine arabinoside (ara-C) and high-dose ara-C in acute leukemia.
Topics: Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Humans; Hydroxyurea; Interphase; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Thymidine | 1985 |
Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells.
Topics: Aminoacridines; Amsacrine; Animals; Bleomycin; Cell Survival; Cytarabine; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Synergism; Hydroxyurea; Intercalating Agents; Leukemia L1210; Mice | 1984 |
Regression supports two mechanisms of fork processing in phage T4.
Topics: Amsacrine; Bacteriophage T4; DNA Replication; Endodeoxyribonucleases; Escherichia coli; Hydroxyurea; Models, Biological; Mutation; Replication Origin; Viral Proteins | 2008 |