amsacrine has been researched along with ellipticine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Denny, WA; Feigon, J; Kearns, DR; Leupin, W | 1 |
| Chiarelotto, G; Dalla Via, L; Ferlin, MG; Gia, O | 1 |
| Barone, V; Brancato, G; Da Settimo, F; Dalla Via, L; Di Giovanni, C; Gia, O; La Motta, C; Lavecchia, A; Magno, SM; Marini, AM; Novellino, E; Salerno, S; Simorini, F; Taliani, S | 1 |
| Chilin, A; Dalla Via, L; Guiotto, A; Marzaro, G; Toninello, A | 1 |
| Bist, G; Kadayat, TM; Kwon, Y; Lee, ES; Lee, HJ; Park, S; Shrestha, A; Thapa Magar, TB | 1 |
| Barresi, E; Da Settimo, F; Dalla Via, L; García-Argáez, AN; Hyeraci, M; La Pietra, V; Marinelli, L; Marini, AM; Milite, C; Novellino, E; Robello, M; Salerno, S; Simorini, F; Taliani, S | 1 |
| Sumner, AT | 1 |
| DeMarini, DM; Lawrence, BK | 1 |
| Evans, HH; Horng, MF; Mencl, J; Ricanati, M | 1 |
| Bisagni, E; de Cointet, P; Gros, P; Nguyen, CH; Pierre, A; Pierson, V | 1 |
| Gras, MP; Larsen, CJ; Multon, E; Riou, JF; Vilarem, MJ | 1 |
| Shall, S; Tavassoli, M; Tavassoli, MH | 1 |
| Kohn, KW; Pommier, Y; Schwartz, RE; Zwelling, LA | 1 |
| Best-Belpomme, M; Nahon, E; Saucier, JM | 1 |
| Jo, K; Topal, MD | 1 |
| Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R | 1 |
| Phan, TN; Tuteja, N | 1 |
| Kajorndechakiat, S; Petmitr, PC; Ramdja, M | 1 |
| Kreuzer, KN; O'Reilly, EK | 1 |
| Hung, VK; Mak, CK; Wong, JT | 1 |
| Hait, WN; Nayak, MS; Yang, JM | 1 |
21 other study(ies) available for amsacrine and ellipticine
| Article | Year |
|---|---|
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.
Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship | 1984 |
DNA-targeting pyrroloquinoline-linked butenone and chalcones: synthesis and biological evaluation.
Topics: Antineoplastic Agents; Butanones; Cell Line, Tumor; Cell Proliferation; Chalcones; DNA; Humans; Pyrroles; Quinolines; Topoisomerase II Inhibitors | 2009 |
Benzothiopyranoindole-based antiproliferative agents: synthesis, cytotoxicity, nucleic acids interaction, and topoisomerases inhibition properties.
Topics: Cell Proliferation; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Enzyme Inhibitors; Fluorometry; HeLa Cells; HL-60 Cells; Humans; Indoles; Inhibitory Concentration 50; Models, Molecular; Molecular Conformation; Quantum Theory; Thermodynamics; Titrimetry; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2009 |
Benzoquinazoline derivatives as new agents affecting DNA processing.
Topics: Amsacrine; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; DNA; HeLa Cells; Humans; Male; Models, Molecular; Quinazolines; Salmon; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2011 |
Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Biocatalysis; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Design; Humans; Pyridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2017 |
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA; Humans; Indoles; Molecular Docking Simulation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2019 |
Inhibitors of topoisomerases do not block the passage of human lymphocyte chromosomes through mitosis.
Topics: Amsacrine; Camptothecin; Chromosome Aberrations; Chromosomes, Human; Daunorubicin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Ellipticines; Ethidium; Etoposide; Humans; In Vitro Techniques; Lymphocytes; Mitosis; Mitoxantrone; Nalidixic Acid; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1992 |
Prophage induction by DNA topoisomerase II poisons and reactive-oxygen species: role of DNA breaks.
Topics: Amsacrine; Azides; Bacteriophage lambda; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Ellipticines; Escherichia coli; Free Radicals; Hydrogen Peroxide; Lysogeny; Nalidixic Acid; Novobiocin; Oxolinic Acid; Oxygen; Paraquat; Sodium Azide; SOS Response, Genetics; Teniposide; Topoisomerase II Inhibitors; Virus Replication | 1992 |
Relationship between topoisomerase II and radiosensitivity in mouse L5178Y lymphoma strains.
Topics: Amsacrine; Animals; Cells, Cultured; DNA Repair; DNA Topoisomerases, Type II; Ellipticines; Etoposide; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Radiation Tolerance; Species Specificity; Thymidine Kinase | 1989 |
Interrelationship between affinity for DNA, cytotoxicity and induction of DNA-breaks in cultured L1210 cells for two series of tricyclic intercalators. Simplified analogues of ellipticine derivatives.
Topics: Alkaloids; Amsacrine; Animals; Cell Survival; DNA; DNA Damage; DNA, Neoplasm; Ellipticines; Intercalating Agents; Leukemia L1210; Structure-Activity Relationship; Tumor Cells, Cultured | 1989 |
The in vitro involvement of topoisomerase II in the activity of aza-ellipticine analogues is not correlated with drug activity on isolated nuclei.
Topics: Alkaloids; Aminoacridines; Amsacrine; Animals; Cattle; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; DNA; DNA Replication; DNA Topoisomerases, Type II; Electrophoresis, Agar Gel; Ellipticines; Indoles; Isoquinolines; Mice; Trypanosoma cruzi | 1986 |
Effect of DNA intercalators on poly(ADP-ribose) glycohydrolase activity.
Topics: Aminoacridines; Amsacrine; Animals; Chloroquine; Daunorubicin; DNA; Ellipticines; Ethacridine; Ethidium; Glycoside Hydrolases; Histones; Intercalating Agents; Kinetics; Proflavine; Swine; Thymus Gland; Tilorone | 1985 |
Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents.
Topics: Adenosine Triphosphate; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Binding Sites; Daunorubicin; DNA; DNA Repair; DNA, Single-Stranded; Ellipticines; Intercalating Agents; Leukemia L1210; Magnesium; Mice; Sodium Chloride; Topoisomerase I Inhibitors | 1984 |
Analysis of the DNA topoisomerase-II-mediated cleavage of the long terminal repeat of Drosophila 1731 retrotransposon.
Topics: Amsacrine; Animals; Base Sequence; DNA; DNA Topoisomerases, Type II; DNA Transposable Elements; Drosophila; Ellipticines; Etoposide; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid | 1993 |
Changing a leucine to a lysine residue makes NaeI endonuclease hypersensitive to DNA intercalative drugs.
Topics: Amsacrine; Antineoplastic Agents; Binding Sites; Daunorubicin; Deoxyribonuclease EcoRI; Deoxyribonucleases, Type II Site-Specific; DNA Nucleotidyltransferases; DNA Topoisomerases, Type I; Ellipticines; Enzyme Inhibitors; Integrases; Intercalating Agents; Kinetics; Lysine; Nalidixic Acid; Novobiocin; Oxolinic Acid; Point Mutation; Recombinant Proteins; Recombinases; Topoisomerase I Inhibitors | 1996 |
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents.
Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors | 1997 |
Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amsacrine; Camptothecin; Chloroplasts; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Ethidium; Etoposide; Genistein; Hydrolysis; Intercalating Agents; Ligands; Nogalamycin; Novobiocin; Pisum sativum | 1998 |
In vitro sensitivity of Trichomonas vaginalis to DNA topoisomerase II inhibitors.
Topics: Amsacrine; Animals; Anti-Infective Agents; Antitrichomonal Agents; Ellipticines; Enzyme Inhibitors; Fluoroquinolones; Metronidazole; Parasitic Sensitivity Tests; Topoisomerase II Inhibitors; Trichomonas vaginalis | 2000 |
A unique type II topoisomerase mutant that is hypersensitive to a broad range of cleavage-inducing antitumor agents.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amsacrine; Antineoplastic Agents; Bacteriophage T4; Binding Sites; DNA Damage; DNA Topoisomerases, Type II; DNA, Superhelical; Ellipticines; Enzyme Inhibitors; Filtration; Glycine; Mitoxantrone; Molecular Sequence Data; Oxolinic Acid; Podophyllotoxin; Point Mutation; Topoisomerase II Inhibitors; Valine | 2002 |
Type II topoisomerase activities in both the G1 and G2/M phases of the dinoflagellate cell cycle.
Topics: Amsacrine; Animals; Cell Cycle; Chromosomes; Diketopiperazines; Dinoflagellida; DNA Damage; DNA Fragmentation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Ellipticines; Enzyme Inhibitors; Piperazines; Topoisomerase II Inhibitors | 2005 |
Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Line, Tumor; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Ellipticines; Etoposide; Humans; Immunoblotting; Mice; Microscopy, Confocal; Mitoxantrone; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Reverse Transcriptase Polymerase Chain Reaction | 2007 |