amsacrine and carbostyril

amsacrine has been researched along with carbostyril in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, IK; Gootz, TD; McGuirk, PR; Muller, MT; Spitzner, JR1
Coughlin, SA; Evans, AC; Huff, AC; Rake, JB; Robinson, RG; Selander, KN; Wentland, MP1
Corbett, AH; Elsea, SH; Osheroff, N; Westergaard, M1
Corbett, AH; Osheroff, N; Robinson, MJ1
Corbett, AH; Hong, D; Osheroff, N1
Burden, DA; Elsea, SH; Lomenick, JP; Osheroff, N; Westergaard, M1
Fan, L; Raisch, KP; Shinkre, BA; Velu, SE1

Reviews

1 review(s) available for amsacrine and carbostyril

ArticleYear
Defining functional drug-interaction domains on topoisomerase II by exploiting mechanistic differences between drug classes.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl

    Topics: Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; DNA; DNA Damage; DNA Topoisomerases, Type II; Etoposide; Fluoroquinolones; Genistein; Humans; Isoflavones; Models, Structural; Quinolones; Topoisomerase II Inhibitors

1994

Other Studies

6 other study(ies) available for amsacrine and carbostyril

ArticleYear
Analysis of eukaryotic topoisomerase II cleavage sites in the presence of the quinolone CP-115,953 reveals drug-dependent and -independent recognition elements.
    Molecular pharmacology, 1995, Volume: 48, Issue:2

    Topics: Amsacrine; Anti-Infective Agents; Base Sequence; DNA; DNA Topoisomerases, Type II; Etoposide; Fluoroquinolones; Humans; Hydrolysis; Molecular Sequence Data; Quinolones; Teniposide; Topoisomerase II Inhibitors

1995
DNA sequence preferences at sites cleaved by human DNA topoisomerase II in response to novel quinolone derivatives.
    Anti-cancer drug design, 1995, Volume: 10, Issue:3

    Topics: Amsacrine; Base Sequence; DNA; DNA Topoisomerases, Type II; HeLa Cells; Humans; Hydrolysis; Molecular Sequence Data; Quinolones; Substrate Specificity; Teniposide; Topoisomerase II Inhibitors

1995
Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II.
    Biochemistry, 1993, Apr-13, Volume: 32, Issue:14

    Topics: Adenosine Triphosphate; Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; Binding Sites; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Bacterial; Drosophila melanogaster; Escherichia coli; Etoposide; Fluoroquinolones; Genistein; Hydrolysis; Isoflavones; Novobiocin; Plasmids; Quercetin; Quinolones; Topoisomerase II Inhibitors

1993
Exploiting mechanistic differences between drug classes to define functional drug interaction domains on topoisomerase II. Evidence that several diverse DNA cleavage-enhancing agents share a common site of action on the enzyme.
    The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19

    Topics: Amsacrine; Animals; Anti-Infective Agents; Binding Sites; Cell Line; Cell Nucleus; DNA; DNA Topoisomerases, Type II; DNA, Superhelical; Drosophila melanogaster; Drug Interactions; Etoposide; Fluoroquinolones; Genistein; Growth Inhibitors; Isoflavones; Kinetics; Novobiocin; Protein Binding; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors

1993
Quinolones share a common interaction domain on topoisomerase II with other DNA cleavage-enhancing antineoplastic drugs.
    Biochemistry, 1997, Mar-11, Volume: 36, Issue:10

    Topics: Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; Binding Sites; CHO Cells; Ciprofloxacin; Cricetinae; DNA Topoisomerases, Type II; DNA, Superhelical; Drosophila melanogaster; Electrophoresis, Agar Gel; Enzyme Activation; Etoposide; Fluoroquinolones; Genistein; Isoflavones; Kinetics; Molecular Structure; Quinolones

1997
Analogs of the marine alkaloid makaluvamines: synthesis, topoisomerase II inhibition, and anticancer activity.
    Bioorganic & medicinal chemistry letters, 2007, May-15, Volume: 17, Issue:10

    Topics: Alkaloids; Amsacrine; Animals; Antineoplastic Agents; Drug Design; Drug Screening Assays, Antitumor; Humans; Marine Biology; Molecular Structure; Pyrroles; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2007