amrinone has been researched along with enoximone in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (55.56) | 18.7374 |
| 1990's | 13 (28.89) | 18.2507 |
| 2000's | 5 (11.11) | 29.6817 |
| 2010's | 2 (4.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barney, CL; Burkhard, T; Ertel, MA; Kariya, T; Kastner, PR; Marshall, FN; Matthews, DP; McCarthy, JR; Shea, PJ; Whitten, JP | 1 |
| Bobowski, G; Bristol, JA; Burke, SE; Evans, DB; Newton, RS; Sircar, I; Steffen, RP; Weishaar, RE | 1 |
| Bristol, JA; Humblet, CC; McPhail, AT; Moos, WH; Rithner, C; Sircar, I; Weishaar, RE | 1 |
| Bobowski, G; Bristol, JA; Duell, BL; Evans, DB; Sircar, I | 1 |
| Bristol, JA; Cain, MH; Weishaar, RE | 1 |
| Erhardt, PW | 1 |
| Hayes, JS; Kauffman, RF; Krushinski, JH; Pollock, GD; Robertson, DW; Wilson, H | 1 |
| Bristol, JA; Evans, DB; Moos, WH; Sircar, I; Weishaar, RE | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Dieterich, HA; Doetsch, N; Dressler, HT; Freund, U; Günnicker, M; Hakim-Meibodi, K; Lockhart, JD; Reidemeister, JC; Schieffer, M; Zerkowski, HR | 1 |
| Lehot, JJ | 1 |
| Ito, M; Masuoka, H; Naka, M; Nakano, T; Tanaka, T | 1 |
| Abdel-Aleem, S; Badr, M; Frangakis, C | 1 |
| Peters, P; Saborowski, F; Schneider, M | 1 |
| Drexler, H; Löllgen, H | 1 |
| Blinks, JR; Endoh, M; Taira, N; Yanagisawa, T | 1 |
| Braunwald, E; Colucci, WS; Wright, RF | 1 |
| Ahn, HS; Eardley, D; Prioli, N; Watkins, R | 1 |
| Keren, G; LeJemtel, TH; Reis, D; Sonnenblick, EH | 1 |
| Baim, DS | 2 |
| Hess, ML; Wood, MA | 1 |
| Janicki, JS; Maskin, CS; Weber, KT | 1 |
| Andersson, KE | 1 |
| Dhainaut, JF | 1 |
| Chiotti, D; Presbitero, P | 1 |
| Uretsky, BF | 1 |
| Leier, CV | 1 |
| Beavo, JA; Chang, ML; Harrison, SA | 1 |
| Tommaso, CL | 1 |
| Beavo, JA; Cadd, GG; Gallis, B; Harrison, SA; Reifsnyder, DH | 1 |
| van Meel, JC | 1 |
| Carlier, J; D'Orio, V; el Allaf, D | 1 |
| Günnicker, M; Marggraf, G; Reidemeister, JC; Zerkowski, HR | 1 |
| Lindeborg, DM; Pearl, RG | 1 |
| Levy, JH; Salmenperä, M | 1 |
| Pfaffendorf, M; van Wezel, HB; van Zwieten, PA; Vroom, MB | 1 |
| Braune, J; Ebert, U; Grossmann, M; Kirch, W | 1 |
| Heintz, B; Kirsten, D; Kirsten, R; Nelson, K | 1 |
| Bozkurt, AK; Köksal, C; Köseoğlu, S; Süzer, O | 1 |
| Graf, BM; Grube, C; Martin, E; Stowe, DF; Zausig, YA; Zink, W | 1 |
13 review(s) available for amrinone and enoximone
| Article | Year |
|---|---|
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity | 1985 |
In search of the digitalis replacement.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Cyclic AMP; Digitalis Glycosides; Heart Failure; Humans; Myocardial Contraction; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1987 |
Use of inotropes in the critical care setting.
Topics: Amrinone; Cardiotonic Agents; Dobutamine; Dopamine; Enoximone; Epinephrine; Humans; Imidazoles; Milrinone; Norepinephrine; Phosphodiesterase Inhibitors; Pyridones; Stimulation, Chemical | 1990 |
New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 2.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Administration, Oral; Aminopyridines; Amrinone; Cardiotonic Agents; Coenzymes; Enoximone; Heart; Heart Failure; Hemodynamics; Humans; Imidazoles; Injections, Intravenous; Milrinone; Nifedipine; Oxyfedrine; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Quinazolines; Ubiquinone | 1986 |
The role of novel inotropic agents in the treatment of heart failure.
Topics: Amrinone; Animals; Cardiotonic Agents; Dobutamine; Enoximone; Heart Failure; Hemodynamics; Humans; Imidazoles; Milrinone; Myocardial Contraction; Physical Exertion; Pyridazines; Pyridones; Time Factors | 1986 |
Long-term oral therapy of congestive heart failure with phosphodiesterase inhibitors.
Topics: Administration, Oral; Amrinone; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Phosphodiesterase Inhibitors; Pyridones | 1989 |
Effects of new inotropic agents on exercise performance.
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiac Output; Cardiotonic Agents; Chronic Disease; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Muscles; Oxygen; Oxygen Consumption; Physical Exertion; Pulmonary Wedge Pressure; Pyridones; Time Factors | 1986 |
Some new positive inotropic agents.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiotonic Agents; Dobutamine; Dopamine; Drug Tolerance; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Phosphodiesterase Inhibitors; Practolol; Prenalterol; Pyridones | 1986 |
[New inotropic drugs].
Topics: Adrenergic beta-Agonists; Amrinone; Cardiotonic Agents; Deoxyepinephrine; Enoximone; Ethanolamines; Heart; Humans; Imidazoles; Milrinone; Myocardial Contraction; Propanolamines; Pyridazines; Pyridones; Vasodilator Agents; Xamoterol | 1988 |
Non-glycoside, non-catecholamine inotropic agents in the treatment of congestive heart failure.
Topics: Administration, Oral; Aminopyridines; Amrinone; Arrhythmias, Cardiac; Calcium; Cardiac Output; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Enoximone; Heart Failure; Hemodynamics; Humans; Imidazoles; Injections, Intravenous; Milrinone; Physical Exertion; Pyridones; Thrombocytopenia; Time Factors | 1986 |
The new inotropic phosphodiesterase inhibitors.
Topics: Aminopyridines; Amrinone; Calcium; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Enoximone; Heart Failure; Hemodynamics; Humans; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridones; Quinazolines; Stimulation, Chemical; Time Factors; Xanthines | 1984 |
Inotropic therapy in the critically ill patient.
Topics: Amrinone; Cardiac Glycosides; Cardiotonic Agents; Catecholamines; Critical Illness; Enoximone; Humans; Milrinone; Pyridones | 1993 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilol; Enoximone; Female; Humans; Iloprost; Imidazoles; Indoramin; Isosorbide Dinitrate; Labetalol; Milrinone; Molsidomine; Nitroglycerin; Nitroprusside; Oxyfedrine; Pentaerythritol Tetranitrate; Phosphodiesterase Inhibitors; Piperazines; Prazosin; Pregnancy; Propanolamines; Pyridones; Theophylline; Trapidil; Vasodilator Agents | 1998 |
4 trial(s) available for amrinone and enoximone
| Article | Year |
|---|---|
Low-output syndrome after heart surgery: is a monotherapy with phosphodiesterase-III inhibitors feasible? A comparative study of amrinone and enoximone.
Topics: Aged; Amrinone; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Enoximone; Female; Hemodynamics; Humans; Male; Middle Aged; Prospective Studies; Single-Blind Method; Treatment Outcome | 1992 |
[The hemodynamic profile of amrinone and enoximone in patients with severe heart failure].
Topics: Aged; Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Disease; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enoximone; Female; Heart Failure; Hemodynamics; Humans; Imidazoles; Infusions, Intravenous; Male; Middle Aged; Phosphodiesterase Inhibitors | 1991 |
[Concept for therapy of heart failure in heart surgery].
Topics: Amrinone; Cardiac Output, Low; Enoximone; Heart Diseases; Heart Failure; Heart Rate; Heart Transplantation; Hemodynamics; Humans; Infusions, Intravenous; Intraoperative Complications; Myocardial Contraction; Postoperative Complications; Prospective Studies; Single-Blind Method | 1994 |
Dilatory effects of phosphodiesterase inhibitors on human hand veins in vivo.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Amrinone; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Enoximone; Female; Hand; Humans; Male; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline; Vasodilation; Vasodilator Agents; Veins | 1998 |
28 other study(ies) available for amrinone and enoximone
| Article | Year |
|---|---|
Synthesis and cardiotonic activity of novel biimidazoles.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Chemical Phenomena; Chemistry; Dogs; Furans; Heart Rate; Imidazoles; Isoenzymes; Milrinone; Molecular Structure; Myocardial Contraction; Pyridones; Rats; Stimulation, Chemical; Structure-Activity Relationship; Thiazoles; Thiophenes | 1990 |
Cardiotonic agents. 9. Synthesis and biological evaluation of a series of (E)-4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]ethenyl]-3 (2H)-pyridazinones: a novel class of compounds with positive inotropic, antithrombotic, and vasodilatory activities for t
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Female; Fibrinolytic Agents; Heart Failure; Humans; Imidazoles; Male; Myocardial Contraction; Platelet Aggregation; Pyridazines; Structure-Activity Relationship; Vasodilator Agents | 1989 |
Cardiotonic agents. 8. Selective inhibitors of adenosine 3',5'-cyclic phosphate phosphodiesterase III. Elaboration of a five-point model for positive inotropic activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Myocardial Contraction; Spectrophotometry, Infrared; X-Ray Diffraction | 1987 |
Cardiotonic agents. 2. Synthesis and structure-activity relationships of 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones: a new class of positive inotropic agents.
Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Chemical Phenomena; Chemistry, Physical; Dogs; Heart Failure; Imidazoles; Myocardial Contraction; Pyridazines; Structure-Activity Relationship | 1985 |
Dihydropyridazinone cardiotonics: synthesis and inotropic activity of 5'-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)spiro[cycloalkane- 1,3'-[3H]indol]-2'(1'H)-ones.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Chemical Phenomena; Chemistry; Dogs; Female; Indoles; Isoenzymes; Male; Myocardial Contraction; Myocardium; Pyridazines; Sarcoplasmic Reticulum; Spiro Compounds; Stimulation, Chemical; Structure-Activity Relationship | 1987 |
Cardiotonic agents. 1. 4,5-Dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3 (2H)-pyridazinones: novel positive inotropic agents for the treatment of congestive heart failure.
Topics: Animals; Cardiotonic Agents; Dogs; Guinea Pigs; Heart Failure; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[New positive inotropic drugs].
Topics: Adrenergic Agonists; Amrinone; Cardiotonic Agents; Dopamine; Enoximone; Hemodynamics; Humans; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Shock, Cardiogenic | 1991 |
Effects of amrinone and enoximone on the subclasses of cyclic AMP phosphodiesterase from human heart and kidney.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adolescent; Adult; Aged; Amrinone; Cardiotonic Agents; Chromatography, DEAE-Cellulose; Enoximone; Female; Heart; Humans; Imidazoles; In Vitro Techniques; Kidney; Kinetics; Male; Myocardium; Subcellular Fractions | 1990 |
Stimulation of fatty acid oxidation in myocytes by phosphodiesterase inhibitors and adenosine analogues.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Amrinone; Animals; Cells, Cultured; Dipyridamole; Enoximone; Heart; Imidazoles; Milrinone; Myocardium; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Rats | 1991 |
Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aequorin; Aminopyridines; Amrinone; Animals; Calcium; Carbachol; Cardiotonic Agents; Colforsin; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Enoximone; Female; Imidazoles; Male; Milrinone; Myocardial Contraction; Myocardium; Nifedipine; Nucleotides, Cyclic; Pyrazines; Pyridones; Quinolines; Time Factors | 1986 |
Effects of several newer cardiotonic drugs on cardiac cyclic AMP metabolism.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Colforsin; Cyclic AMP; Enoximone; Guinea Pigs; Hydrolysis; Imidazoles; Isoenzymes; Milrinone; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyridones | 1986 |
Effect of phosphodiesterase inhibition on myocardial oxygen consumption and coronary blood flow.
Topics: Amrinone; Animals; Coronary Circulation; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Myocardium; Oxygen Consumption; Phosphodiesterase Inhibitors; Pyridones | 1989 |
[Use of new inotropic agents in the treatment of acute cardiac failure].
Topics: Adrenergic Agonists; Amrinone; Calcium Channel Blockers; Cardiotonic Agents; Dobutamine; Dopamine; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Myocardial Contraction; Pyridones | 1988 |
Is inotropic therapy appropriate for patients with chronic congestive heart failure? Or is the digitalis leaf withering?
Topics: Amrinone; Cardiotonic Agents; Digoxin; Dobutamine; Enoximone; Ethanolamines; Heart; Heart Failure; Heart Function Tests; Hemodynamics; Humans; Imidazoles | 1986 |
General overview and update of positive inotropic therapy.
Topics: Amrinone; Blood Pressure; Cardiotonic Agents; Digitoxin; Dobutamine; Dopamine; Enoximone; Heart Failure; Hemodynamics; Humans; Imidazoles; Isoproterenol; Milrinone; Norepinephrine; Phosphodiesterase Inhibitors; Pyridones; Stroke Volume; Time Factors | 1986 |
Differential inhibition of cardiac cyclic nucleotide phosphodiesterase isozymes by cardiotonic drugs.
Topics: Aminopyridines; Amrinone; Animals; Antibodies, Monoclonal; Cardiotonic Agents; Cattle; Cyclic GMP; Enoximone; Imidazoles; Isoenzymes; Mice; Milrinone; Myocardium; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Pyridones; Rabbits | 1986 |
Isolation and characterization of bovine cardiac muscle cGMP-inhibited phosphodiesterase: a receptor for new cardiotonic drugs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Amrinone; Animals; Antibodies, Monoclonal; Cardiotonic Agents; Cattle; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Cyclic GMP; Enoximone; Imidazoles; Immune Sera; Kinetics; Mice; Mice, Inbred BALB C; Milrinone; Molecular Weight; Myocardium; Phosphodiesterase Inhibitors; Phosphorylation; Pyridones | 1986 |
Comparison of some new positive inotropic agents in guinea pigs.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Dose-Response Relationship, Drug; Enoximone; Guinea Pigs; Heart Rate; Hydralazine; Imidazoles; Isoproterenol; Male; Myocardial Contraction; Ouabain; Vasodilation | 1985 |
Effects of amrinone on myocardial energetics in severe congestive heart failure.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Coronary Circulation; Dogs; Enoximone; Heart; Heart Failure; Humans; Imidazoles; Isoproterenol; Milrinone; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphodiesterase Inhibitors; Pyridones | 1985 |
The in vitro effects of phosphodiesterase inhibitors on the human internal mammary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amrinone; Cyclic AMP; Dose-Response Relationship, Drug; Enoximone; Humans; Mammary Arteries; Milrinone; Norepinephrine; Papaverine; Phosphodiesterase Inhibitors; Prostaglandin Endoperoxides, Synthetic; Pyridones; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Effect of phosphodiesterase inhibitors on human arteries in vitro.
Topics: Adolescent; Adult; Amrinone; Analgesics; Anilides; Arginine; Arteries; Dipyridamole; Enoximone; Female; Glyburide; Humans; In Vitro Techniques; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Pyridones; Theophylline; Vasoconstriction; Vasodilation | 1996 |
Comparison of enoximone, amrinone, or levosimendan enriched St. Thomas' hospital cardioplegic solutions used for myocardial preservation in isolated guinea pig hearts.
Topics: Amrinone; Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Cardiotonic Agents; Enoximone; Female; Guinea Pigs; Heart; Heart Arrest, Induced; Hydrazones; In Vitro Techniques; Magnesium; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Organ Preservation; Phosphodiesterase Inhibitors; Potassium Chloride; Pyridazines; Simendan; Sodium Chloride | 2002 |
A comparison of three phosphodiesterase type III inhibitors on mechanical and metabolic function in guinea pig isolated hearts.
Topics: Amrinone; Animals; Cardiotonic Agents; Coronary Circulation; Dose-Response Relationship, Drug; Enoximone; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Milrinone; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphodiesterase Inhibitors; Vasodilation | 2006 |