amrinone has been researched along with alpha-aminopyridine in 216 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 216 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, RS; Forman, R; Greenberg, MA; Keung, EC; LeJemtel, TH; Maskin, CS; Ribner, HS; Schwartz, WJ; Sonnenblick, EH | 1 |
| LeJemtel, T; Mancini, D; Sonnenblick, E | 1 |
| Alousi, AA; Johnson, DC | 1 |
| Blinks, JR; Endoh, M; Taira, N; Yanagisawa, T | 1 |
| Meyer, W; Scholz, H | 1 |
| Braunwald, E; Colucci, WS; Wright, RF | 1 |
| Ahn, HS; Eardley, D; Prioli, N; Watkins, R | 1 |
| Hagen, A; Hagen, V; Heer, S; Mitzner, R; Niedrich, H | 1 |
| Johnston, GD | 1 |
| Packer, M | 1 |
| Acar, J; Le Potier, J; Michel, PL; Sergent, J; Vahanian, A | 1 |
| Janicki, JS; Maskin, CS; Weber, KT | 2 |
| Landmann, H; Löwe, H | 1 |
| Femmer, K; Heer, S; Poppe, H | 1 |
| Andersson, KE | 1 |
| Blas, SD; Cody, V; Davis, FB; Davis, PJ; Mylotte, KM; Schoenl, M | 1 |
| Factor, S; Le Jemtel, TH; Mancini, DM; Sonnenblick, EH | 1 |
| Komajda, M | 1 |
| LeJemtel, TH; Mancini, DM; Sonnenblick, EH | 1 |
| Bassett, AL; Cameron, JS; Gaide, MS; Lodge, NJ | 1 |
| Galatulas, I; Gibelli, N; Supino, R; Zunino, F | 1 |
| Beavo, JA; Chang, ML; Harrison, SA | 1 |
| Brutsaert, DL; Chalant, CH; Goenen, MJ; Sys, SU | 1 |
| Binah, O; Danilo, P; Rosen, M; Sodowick, B; Vulliemoz, Y | 1 |
| Kenyon, JL; Reeves, JP; Sutko, JL | 1 |
| Cohen, SR; Das, D; Isner, JM; Konstam, MA; Martin, TT; Salem, DN; Weiland, DS | 1 |
| Tommaso, CL | 1 |
| Boyd, DK; Evans, DB; Quade, M; Schenden, JA; Weishaar, RE | 1 |
| Beavo, JA; Cadd, GG; Gallis, B; Harrison, SA; Reifsnyder, DH | 1 |
| Imai, H; Imai, S; Matsui, K; Nakahara, H; Nakazawa, M; Takeda, K | 1 |
| Ruggie, N | 1 |
| Bonner, FW; Eason, CT; Pattison, A | 2 |
| van Meel, JC | 1 |
| Baim, DS | 1 |
| Medina, N; Packer, M; Yushak, M | 4 |
| Benotti, J; Benziger, DP; Chatterjee, K; Cody, R; Edelson, J; Hood, WB; Krebs, C; Luczkowec, C; Schwartz, R; Stroshane, R | 1 |
| Goldstein, RA | 1 |
| Farah, AE | 1 |
| Hasegawa, GR | 1 |
| Döring, M; Janowski, K; Koppatz, G; Stade, K | 1 |
| Beedle, EE; Elzey, TK; Hayes, JS; Jones, ND; Kauffman, RF; Robertson, DW; Swartzendruber, JK; Wilson, H | 1 |
| Dorigo, P; Maragno, I | 1 |
| Faust, G; Heidrich, HJ; Heyne, HU; Jänsch, HJ; Lohmann, D; Niedrich, H; Schrötter, E | 1 |
| Hagen, V; Mayer, W; Mehlis, B; Mitzner, R; Niedrich, H; Seifert, H; Usbeck, H | 1 |
| Fischer, R; Frömmel, B; Göres, E; Hagen, A; Hennig, R; Just, E; Landmann, H; Sonnenburg, F | 1 |
| Blasig, IE; Hergenröther, D; Krause, EG; Löwe, H; Rohde, E; Schulz, U | 1 |
| Göres, E; Hagen, A; Krause, W | 1 |
| Landmann, H; Löwe, H; Modersohn, D; Muschick, P; Rohde, E | 1 |
| Chemnitius, KH; Elze, M; Hübler, D; Mudhaffar, AA; Schilling, G | 1 |
| Al Mudhaffar, A; Chemnitius, KH; Hübler, D; Schilling, G | 1 |
| Frömmel, B; Göres, E; Grünheid, K; Hagen, A; Lengwinat, T; Morgenstern, E; Stattmann, A | 1 |
| Göres, E; Janowski, K; Kedor, S | 1 |
| Janowski, K; Stade, K; Zschorn, EM | 1 |
| Göres, E; Janowski, K; Landmann, H | 1 |
| Frosch, I; Männel, S | 1 |
| Nielsen-Kudsk, F; Vigholt Sørensen, E | 1 |
| Koprda, V; Landmann, H; Trnovec, T | 1 |
| Kapur, PA; Makela, VH | 1 |
| Aronovitz, MJ; Brockway, BA; Cohen, SR; Das, D; Konstam, MA; Salem, DN | 1 |
| Gage, J; LeJemtel, TH; Lucido, D; Rutman, H | 1 |
| Guimond, JG; Keating, D; Matuschak, GM; Meyers, F | 1 |
| Asselin, A; Dionne, G; Humber, LG; McQuillan, J; Treasurywala, AM | 1 |
| Furlan, CC; Tucci, PJ | 1 |
| Edman, KA; Månsson, A | 2 |
| Bourassa, M; DiBianco, R; Hess, M; Konstam, M; Likoff, M; Massie, B; Packer, M | 1 |
| Treadway, G | 1 |
| Bounhoure, JP; Calazel, J; Massabuau, P; Miquel, JP; Puel, J | 1 |
| Büll, U; Kleinhans, E; Klepzig, M; Strauer, BE | 1 |
| Wilmshurst, P | 2 |
| Horwitz, PM; Hyman, AL; Ignarro, LJ; Kadowitz, PJ; Landry, AZ; Lippton, HL; McNamara, DB | 1 |
| Bassett, AL; Cameron, JS; Gaide, MS; Kimura, S; Kozlovskis, PL; Lodge, NJ; Myerburg, RJ | 1 |
| Krieger, NS; Stathopoulos, VM; Stern, PH | 1 |
| DeFeo, TT; Gwathmey, JK; Morgan, JP; Morgan, KG | 1 |
| Applefeld, MM | 1 |
| Goldfarb, JP; LeJemtel, TH; Manzione, NC; Maskin, CS; Sternlieb, I | 1 |
| Arlock, P; Katzung, BG; Malécot, CO | 1 |
| Franciosa, JA | 1 |
| Crause, L; MacGillivray, RG; Odell, JA; Rozwadowski, MA | 1 |
| Brückner, JB; Hess, W; Veit, S; Vogt, K; Wagner, R | 1 |
| Gerber, L; Merrill, AJ; Silverman, BD | 1 |
| Coltart, DJ; Dawson, JR; Dittrich, HC; Jenkins, BS; Juul, SM; Thompson, DS; Walker, JM; Webb-Peploe, MM; Wilmshurst, PT | 1 |
| Brown, L; Erdmann, E | 2 |
| Fukatsu, O; Gonda, T; Kosugi, I; Moriyasu, N; Okada, K; Tajimi, K | 1 |
| Braunwald, E | 1 |
| Alpert, JS; Benotti, JR; McCue, JE | 1 |
| Dougherty, AH; Goldstein, RA; Gray, EL; Naccarelli, GV | 1 |
| Hafizullah, M; Hussain, M; Jackson, NC; Reynolds, G; Richmond, A; Silke, B; Taylor, SH; Verma, SP | 1 |
| Baele, P; Col, J; Goenen, M; Pedemonte, O | 1 |
| Goldstein, RA; Naccarelli, GV | 1 |
| Alousi, AA; Canter, JM; Fort, DJ | 1 |
| Boucek, MM; Chang, R; Synhorst, DP | 1 |
| Fukatsu, O; Gonda, T; Kosugi, I; Tajimi, K; Ueda, S | 1 |
| Hoffmann, P; Schockenhoff, B | 1 |
| Goldberg, LI | 1 |
| Carlier, J; D'Orio, V; el Allaf, D | 1 |
| Boder, GB; Bowling, N; Hayes, JS; Kauffman, R | 1 |
| Sharpe, DN | 1 |
| Cargnelli, G; Carpenedo, F; Floreani, M | 1 |
| Andrews, V; Fishman, AP; Janicki, JS; Kinasewitz, GT; Weber, KT | 1 |
| Ishida, Y; Ohizumi, Y; Shibata, S | 1 |
| Bijak, A; Czołpiński, T | 1 |
| Bayliss, J; Canepa-Anson, R; Dawson, JR; Kuan, P; Norell, MS; Poole-Wilson, PA; Reuben, S; Sutton, GC | 1 |
| Jaillon, P | 1 |
| Scholz, H | 2 |
| Carlier, J; el Allaf, D | 1 |
| Alfiero, R; Cocco, G; Padula, A; Rizzo, A; Strozzi, C; Tasini, MT; Urso, L | 1 |
| Fowler, NO; Gabel, M; Millard, RW | 1 |
| Detry, JM; Mancia, G; Pouleur, H | 1 |
| Cocco, G; Sfrisi, C | 1 |
| Azari, J; Huxtable, RJ | 1 |
| Jacoby, M; Levine, SD; Satriano, JA; Schlondorff, D | 1 |
| Honerjäger, P; Reiter, M; Schäfer-Korting, M | 1 |
| Endoh, M; Taira, N; Yamashita, S | 1 |
| Bova, S; Cargnelli, G; Ferrari, M; Padrini, R; Piovan, D | 1 |
| Chesebro, JH; Morgan, JP; Pluth, JR; Puga, FJ; Schaff, HV | 1 |
| Le Jemtel, TH; Maskin, CS; Sonnenblick, EH | 1 |
| Hosokawa, T; Kojima, M; Mori, T; Yabuuchi, Y; Yamashita, S | 1 |
| Humen, DP; Johnston, DL; Kostuk, WJ | 1 |
| Jerie, P | 1 |
| Méndez, R | 1 |
| Larbig, D; Nasse, H | 1 |
| Avery, GS; Brogden, RN; Heel, RC; Speight, TM; Ward, A | 1 |
| Taira, N | 1 |
| Oldershaw, PJ; Smith, LD | 1 |
| Bashore, TM; Evans, JR; Huss, P; Leier, CV; Pacht, K; Unverferth, DV | 1 |
| Benotti, JR; DiBianco, R; Leier, CV; Shabetai, R; Silverman, BD | 1 |
| Andrews, V; Janicki, JS; Likoff, MJ; Weber, KT | 1 |
| Forman, R; Frishman, W; LeJemtel, TH; Maskin, C; Ribner, H; Siegel, LA; Sonnenblick, EH; Strom, J; Wexler, J | 1 |
| Boncyk, J; Redon, D; Rusy, B | 1 |
| Dougherty, AH; Goldstein, RA; Gray, EL; Hanna, JE; Naccarelli, GV | 1 |
| Levene, D; Secter, RA | 1 |
| Kulik, TJ; Lock, JE | 1 |
| Katzung, BG; Malécot, CO | 1 |
| Onuaguluchi, G; Tanz, RD | 1 |
| Benassi, A; Mattioli, G; Modena, MG | 1 |
| Firth, BG; Grassman, ED; Hillis, LD; Nicod, P; Ratner, AV; Winniford, MD | 1 |
| Komai, H; Rusy, BF | 1 |
| Baur, X; Fruhmann, G; Hauser, F; Klepzig, M; Mernitz, G; Strauer, BE | 1 |
| Hashimoto, K; Mori, T; Yabuuchi, Y; Yamashita, S | 1 |
| Demers, LM; Draganis, T; Kinney, EL; Luderer, JR | 1 |
| Miyazaki, M; Nakajima, M; Nishimura, K; Toda, N | 1 |
| Einzig, S; Kulik, TJ; Lock, JE; Mammel, MC; Thompson, TR | 1 |
| Ballard, JO; Carlin, B; Kinney, EL; Zelis, R | 1 |
| Binah, O; Rosen, MR | 1 |
| Mallov, S | 1 |
| Ganz, R; Levy, PS; Rich, S | 1 |
| McCawley, E; Onuaguluchi, G; Tanz, RD | 1 |
| LeJemtel, TH | 1 |
| Kodama, I; Kondo, N; Shibata, S | 1 |
| Bashore, TM; Dalpiaz, K; Hermiller, JB; Huss, P; Leier, CV; Magorien, RD; Unverferth, DV | 1 |
| Hermiller, JB; Leier, CV; Leithe, ME; Magorien, RD; Unverferth, DV | 1 |
| Andrews, V; Janicki, JS; Likoff, MJ; Rocci, ML; Sutton, MS; Weber, KT; Wilson, H | 1 |
| Ansell, J; Benotti, JR; McCue, J; Parrilla, N; Tiarks, C | 1 |
| Al-Hasani, SF; Hamblin, AS; Kioy, PG; Lucas, GF; Savidge, GF; Semple, MJ; Webb-Peploe, MM; Wilmshurst, PT | 1 |
| Gillmer, DJ; Kark, P | 1 |
| Davies, MJ; Fry, CH; Mounsey, JP; Twort, CH; Walker, JM; Webb-Peploe, MM; Williams, BT; Wilmshurst, PT | 1 |
| Coltart, DJ; Jenkins, BS; Juul, SM; Thompson, DS; Webb-Peploe, MM; Wilmshurst, PT | 1 |
| Brandt, JT; Hermiller, J; Leier, CV; Miller, L; Unverferth, DV | 1 |
| Braunwald, E; DeBoer, LW; Karaffa, S; Khuri, S; Kloner, RA; Maroko, PR; Rude, RE | 1 |
| Einzig, S; Johnson, GJ; Rao, GH; White, JG | 1 |
| Coltart, DJ; Jenkins, BS; Thompson, DS; Webb-Peploe, MM; Wilmshurst, PT | 1 |
| Bayliss, J; Canepa-Anson, R; Norell, M; Poole-Wilson, PA; Reuben, SR; Sutton, GC | 1 |
| Hayward, R | 1 |
| Webb-Peploe, MM; Wilsmhurst, PT | 1 |
| Dunkman, WB; Franciosa, JA; Wilen, MM | 1 |
| Peyregne, EA; Reader, C; Suárez, LD | 1 |
| Daly, K; Jewitt, DE; Timmis, A | 1 |
| Binah, O; Danilo, P; Legato, MJ; Rosen, MR | 1 |
| Hill, NS; Rounds, S | 1 |
| Borgoglio, R; Osella, R; Piacenza, G | 1 |
| Angellotti, J; Edelson, J; Kershner, RP; McMahon, FG; Park, GB; Ryan, JJ | 1 |
| Juillere, Y; Royer, RJ; Zannad, F | 1 |
| Aronson, RS; Hertzberg, J; Nusrat, A; Sonnenblick, EH; Tepper, D | 1 |
| Angellotti, J; Benet, LZ; Edelson, J; Kershner, RP; Park, GB; Williams, RL | 1 |
| Casiglia, E; Ferrari, M; Miglioli, PA; Padrini, R; Piovan, D | 1 |
| Barrett, PA; Chong, B; Lvoff, R; Robinson, PJ | 1 |
| Forman, R; Klein, NA; LeJemtel, TH; Maskin, CS; Sonnenblick, EH | 1 |
| Ferrier, GR; Rosenthal, JE | 1 |
| Andrews, V; Janicki, JS; Weber, KT | 1 |
| Einzig, S; Pierpont, ME; Rao, GH; White, JG | 1 |
| Cargnelli, G; Ferrari, M; Gallucci, V; Padrini, R; Piacenza, G; Piovan, D | 1 |
| Adams, HR; Rhody, J; Sutko, JL | 1 |
| Krieger, NS; Stern, PH | 1 |
| Maruyama, M; Satoh, K; Taira, N | 2 |
| Bossa, R; Galatulas, I; Savi, G; Supino, R; Zunino, F | 1 |
| Benotti, JR; Lesko, LJ; McCue, JE | 1 |
| Ballard, JO; Burks, JM; Carlin, B; Hallahan, WF; Kinney, EL; Zelis, R | 1 |
| Buck, DC; Mielens, ZE | 1 |
| Alousi, AA; Biddlecome, CE; Edelson, J; LeJemtel, TH; Maskin, CS; Sonnenblick, EH | 1 |
| Hwang, O; Meisheri, KD; van Breemen, C | 1 |
| Andrews, V; Fishman, AP; Janicki, JS; Weber, KT; Wilson, JR | 1 |
| Frishman, WH; Klein, NA; LeJemtel, TH; Siskind, SJ; Sonnenblick, EH | 1 |
| Jentzer, JH; Kirk, ES; Lejemtel, TH; Sonnenblick, EH | 1 |
| Benotti, JR; Braunwald, E; Carabello, BA; Colucci, WS; Grossman, W; Malacoff, R; Rude, RE; Wynne, J | 1 |
| Forman, R; LeJemtel, TH; Scheuer, J; Siskind, SJ; Sonnenblick, EH | 1 |
| Dorrbecker, B; Edelson, J; Kullberg, MP; Lennon, J; Rowe, E | 1 |
| Benotti, JR; Braunwald, E; Curfman, GD; Grossman, W; Holman, BL; Malacoff, RF; Smith, TW; Wynne, J | 1 |
| Dobbs, W; Katz, AM; McCall, D; Messineo, FC; Pappano, A | 1 |
| Benotti, JR; Braunwald, E; Carabello, BA; Grossman, W | 1 |
| Harper, JR; Parker, JC | 1 |
| Alousi, A; Dubé, G; Grupp, G; Grupp, I; Millard, RW; Schwartz, A | 1 |
| Efstathakis, D; Feinberg, H; Forman, R; Keung, E; LeJemtel, TH; Siegel, LA; Siskind, SJ; Sonnenblick, EH; Strom, J | 1 |
| Alousi, AA; Biddlecome, C; Edelson, J; Freeman, GB; Kullberg, MP | 1 |
24 review(s) available for amrinone and alpha-aminopyridine
| Article | Year |
|---|---|
Intravenous use of amrinone for the treatment of the failing heart.
Topics: Aminopyridines; Amrinone; Cardiac Complexes, Premature; Cardiac Output; Cardiotonic Agents; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Diseases; Heart Failure; Humans; Injections, Intravenous; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphodiesterase Inhibitors; Pulmonary Wedge Pressure; Thrombocytopenia; Vasodilator Agents | 1985 |
New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 2.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Administration, Oral; Aminopyridines; Amrinone; Cardiotonic Agents; Coenzymes; Enoximone; Heart; Heart Failure; Hemodynamics; Humans; Imidazoles; Injections, Intravenous; Milrinone; Nifedipine; Oxyfedrine; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Quinazolines; Ubiquinone | 1986 |
Vasodilator therapy for primary pulmonary hypertension. Limitations and hazards.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Aminopyridines; Amrinone; Blood Pressure; Calcium Channel Blockers; Captopril; Heart Failure; Hemodynamics; Humans; Hypertension, Pulmonary; Hypotension; Lung; Oxygen; Oxygen Inhalation Therapy; Parasympathomimetics; Prostaglandins; Pulmonary Artery; Vascular Resistance; Vasodilator Agents | 1985 |
Effects of new inotropic agents on exercise performance.
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiac Output; Cardiotonic Agents; Chronic Disease; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Muscles; Oxygen; Oxygen Consumption; Physical Exertion; Pulmonary Wedge Pressure; Pyridones; Time Factors | 1986 |
Some new positive inotropic agents.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiotonic Agents; Dobutamine; Dopamine; Drug Tolerance; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Phosphodiesterase Inhibitors; Practolol; Prenalterol; Pyridones | 1986 |
Central and peripheral components of cardiac failure.
Topics: Aminopyridines; Amrinone; Animals; Captopril; Cardiac Output; Cardiomegaly; Cardiotonic Agents; Catecholamines; Coronary Circulation; Diuretics; Drug Therapy, Combination; Heart Failure; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Isotonic Contraction; Microcirculation; Muscles; Norepinephrine; Oxygen Consumption; Renal Circulation; Vasodilator Agents | 1986 |
Non-glycoside, non-catecholamine inotropic agents in the treatment of congestive heart failure.
Topics: Administration, Oral; Aminopyridines; Amrinone; Arrhythmias, Cardiac; Calcium; Cardiac Output; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Enoximone; Heart Failure; Hemodynamics; Humans; Imidazoles; Injections, Intravenous; Milrinone; Physical Exertion; Pyridones; Thrombocytopenia; Time Factors | 1986 |
Congestive heart failure.
Topics: Aminopyridines; Amrinone; Angiotensin-Converting Enzyme Inhibitors; Cardiac Glycosides; Cardiotonic Agents; Diuretics; Dobutamine; Dopamine; Heart Failure; Humans; Hydralazine; Milrinone; Nitrates; Nitroprusside; Prazosin; Pyridones; Sympathomimetics; Vasodilator Agents | 1986 |
Clinical effects of intravenous amrinone in patients with congestive heart failure.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Electrophysiology; Heart Failure; Hemodynamics; Humans; Infusions, Parenteral; Myocardium; Oxygen Consumption | 1986 |
Milrinone, a new agent for the treatment of congestive heart failure.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Heart Failure; Hemodynamics; Humans; Milrinone; Pyridones | 1986 |
Advances in cardiovascular pharmacology.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aminopyridines; Amrinone; Animals; Calcium Channel Blockers; Cardiovascular Agents; Dopamine; Heart Rate; Humans; Imidazoles; Milrinone; Myocardial Contraction; Pyridones; Receptors, Histamine; Vasodilator Agents | 1984 |
The new inotropic phosphodiesterase inhibitors.
Topics: Aminopyridines; Amrinone; Calcium; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Enoximone; Heart Failure; Hemodynamics; Humans; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridones; Quinazolines; Stimulation, Chemical; Time Factors; Xanthines | 1984 |
Newer inotropic agents.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Dobutamine; Ethanolamines; Heart Failure; Humans; Practolol; Prenalterol; Receptors, Adrenergic, beta | 1984 |
Vasodilator and inotropic agents in treatment of chronic cardiac failure: clinical experience and response in exercise performance.
Topics: Aerobiosis; Aminopyridines; Amrinone; Anaerobiosis; Cardiotonic Agents; Heart Failure; Hemodynamics; Humans; Hydralazine; Neurotransmitter Agents; Physical Exertion; Piperazines; Quinazolines; Sympathetic Nervous System; Vasodilator Agents | 1981 |
[New drugs with positive inotropic action].
Topics: Adrenergic beta-Agonists; Albuterol; Aminopyridines; Amrinone; Cardiotonic Agents; Chronic Disease; Ethanolamines; Heart Failure; Humans; Myocardial Contraction; Practolol; Prenalterol; Stimulation, Chemical; Terbutaline | 1982 |
Old and new inotropic drugs.
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiac Glycosides; Cardiotonic Agents; Catecholamines; Glucagon; Hemodynamics; Humans; Imidazoles; Isoproterenol; Myocardial Contraction; Practolol; Prenalterol; Propanolamines; Stimulation, Chemical; Xamoterol | 1984 |
[Old and new positive inotropic drugs: problems and controversies].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiotonic Agents; Glucagon; Glucosides; Heart Failure; Histamine; Humans; Imidazoles; Inosine; Quinazolines; Xanthines | 1984 |
[Positive inotropic therapy of cardiac failure: old and new drugs, controversies and tests].
Topics: Aminopyridines; Amrinone; Cardiac Glycosides; Cardiotonic Agents; Glucagon; Heart Failure; Histamine; Humans; Imidazoles; Inosine; Phosphodiesterase Inhibitors; Quinazolines; Sympathomimetics | 1984 |
Inotropic drugs and their mechanisms of action.
Topics: Aminopyridines; Amrinone; Calcium; Cardiac Glycosides; Cardiotonic Agents; Cyclic AMP; Glucagon; Histamine; Humans; Imidazoles; Myocardial Contraction; Myocardium; Practolol; Prenalterol; Sodium-Potassium-Exchanging ATPase; Sympathomimetics; Xanthines | 1984 |
[Treatment of refactory heart failure].
Topics: Adult; Aged; Aminopyridines; Amrinone; Captopril; Diet, Sodium-Restricted; Digitalis Glycosides; Diuretics; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Female; Heart Failure; Humans; Male; Medication Errors; Middle Aged; Oxygen Inhalation Therapy; Sodium | 1983 |
[The old digitalis and the new cardiac inotropic agents].
Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardenolides; Cardiotonic Agents; Digitalis Glycosides; Dobutamine; Dopamine; Drug Evaluation; Ethanolamines; Humans; Imidazoles | 1983 |
Amrinone. A preliminary review of its pharmacological properties and therapeutic use.
Topics: Absorption; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Half-Life; Heart; Heart Failure; Hemodynamics; Humans; Kinetics; Muscle, Smooth; Muscle, Smooth, Vascular; Papillary Muscles; Physical Exertion; Rabbits; Rats; Regional Blood Flow; Tissue Distribution | 1983 |
[Amrinone, a new cardiotonic agent].
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Guinea Pigs; Heart Failure; Humans; Myocardial Contraction | 1983 |
Inotropic and vasopressor agents.
Topics: Aminophylline; Aminopyridines; Amrinone; Animals; Blood Circulation; Cardiac Glycosides; Cardiotonic Agents; Catecholamines; Cats; Glucagon; Hemodynamics; Humans; Myocardial Contraction; Nerve Endings; Phosphodiesterase Inhibitors; Sympathetic Nervous System; Vasoconstrictor Agents | 1984 |
10 trial(s) available for amrinone and alpha-aminopyridine
| Article | Year |
|---|---|
Pharmacokinetics of the bipyridines amrinone and milrinone.
Topics: Administration, Oral; Aminopyridines; Amrinone; Clinical Trials as Topic; Half-Life; Heart Failure; Humans; Infusions, Parenteral; Kinetics; Male; Milrinone; Pyridones; Random Allocation; Time Factors | 1986 |
Long-term oral administration of amrinone for congestive heart failure: lack of efficacy in a multicenter controlled trial.
Topics: Administration, Oral; Aminopyridines; Amrinone; Cardiotonic Agents; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise Test; Female; Heart Failure; Humans; Male; Middle Aged; Prospective Studies; Random Allocation; Stroke Volume; Time Factors | 1985 |
Clinical safety of intravenous amrinone--a review.
Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiotonic Agents; Clinical Trials as Topic; Drug Interactions; Gastrointestinal Diseases; Heart Failure; Humans; Hypotension; Thrombocytopenia | 1985 |
[Effects of amrinone administered orally and by injection in heart failure].
Topics: Administration, Oral; Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Clinical Trials as Topic; Heart Failure; Hemodynamics; Humans; Infusions, Parenteral; Injections, Intravenous; Middle Aged; Thrombocytopenia | 1985 |
Intravenous amrinone in left ventricular failure complicated by acute myocardial infarction.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Cardiac Output; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart Failure; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Infarction; Random Allocation; Stroke Volume; Vascular Resistance | 1985 |
Chronic oral amrinone therapy in congestive heart failure: a double-blind placebo-controlled withdrawal study.
Topics: Administration, Oral; Adult; Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Heart Failure; Humans; Male; Middle Aged; Platelet Count; Substance Withdrawal Syndrome | 1984 |
Oral amrinone for the treatment of chronic congestive heart failure: results of a multicenter randomized double-blind and placebo-controlled withdrawal study.
Topics: Adult; Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Heart Failure; Humans; Male; Middle Aged; Random Allocation | 1984 |
Intravenous amrinone for congestive heart failure.
Topics: Administration, Oral; Aminopyridines; Amrinone; Cardiotonic Agents; Clinical Trials as Topic; Heart Failure; Humans; Injections, Intravenous | 1984 |
Amrinone therapy for congestive heart failure in outpatients with idiopathic dilated cardiomyopathy.
Topics: Aminopyridines; Amrinone; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Female; Heart Failure; Humans; Male; Middle Aged; Physical Exertion | 1983 |
Acute haemodynamic comparison of amrinone and pirbuterol in chronic heart failure. Additional effects of isosorbide dinitrate.
Topics: Adult; Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Chronic Disease; Drug Therapy, Combination; Ethanolamines; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged | 1983 |
182 other study(ies) available for amrinone and alpha-aminopyridine
| Article | Year |
|---|---|
Hemodynamic effects of intravenous and oral amrinone in patients with severe heart failure: relationship between intravenous and oral administration.
Topics: Administration, Oral; Aminopyridines; Amrinone; Dose-Response Relationship, Drug; Female; Heart Failure; Hemodynamics; Humans; Injections, Intravenous; Male | 1979 |
Pharmacology of the bipyridines: amrinone and milrinone.
Topics: Acetylcholine; Aminopyridines; Amrinone; Animals; Calcium; Carbachol; Cardiotonic Agents; Cats; Cyclic AMP; Dibutyryl Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart; Hemodynamics; Ion Channels; Male; Milrinone; Myocardial Contraction; Norepinephrine; Potassium; Pyridones; Receptors, Muscarinic; Sodium; Stimulation, Chemical; Time Factors; Verapamil | 1986 |
Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aequorin; Aminopyridines; Amrinone; Animals; Calcium; Carbachol; Cardiotonic Agents; Colforsin; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Enoximone; Female; Imidazoles; Male; Milrinone; Myocardial Contraction; Myocardium; Nifedipine; Nucleotides, Cyclic; Pyrazines; Pyridones; Quinolines; Time Factors | 1986 |
Phosphodiesterase-inhibiting properties of newer inotropic agents.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Theophylline | 1986 |
Effects of several newer cardiotonic drugs on cardiac cyclic AMP metabolism.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Colforsin; Cyclic AMP; Enoximone; Guinea Pigs; Hydrolysis; Imidazoles; Isoenzymes; Milrinone; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyridones | 1986 |
[Potential cardiotonic agents. 1. Synthesis and pharmacologic properties of 3-cyano-2-oxaalkylamino-5-(4-pyridinyl)pyridines].
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Chemical Phenomena; Chemistry; Dogs; Guinea Pigs; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Milrinone; Pyridines; Pyridones | 1989 |
Alternatives to the digitalis glycosides for heart failure.
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiotonic Agents; Heart Failure; Humans; Milrinone; Pyridones | 1985 |
[Positive inotropic agents. Generalities and classification].
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Calcium; Cardiotonic Agents; Digitalis Glycosides; Dobutamine; Ethanolamines; Heart Failure; Heart Ventricles; Humans; Myocardial Contraction; Phosphodiesterase Inhibitors; Practolol; Prenalterol | 1985 |
[Non-glycoside cardiotonic agents].
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Blood Pressure; Cardiotonic Agents; Cyclic AMP; Dobutamine; Heart; Hemodynamics; Humans; Phosphodiesterase Inhibitors; Vasodilator Agents | 1986 |
[Animal experimental studies on the therapeutic action of 5-(4-pyridino)-3-amino-1,2-dihydro-pyridinone (Cordemcura, AWD 08-250) in acute cardiocirculatory failure caused by poisoning by beta receptor blockers].
Topics: Adrenergic beta-Antagonists; Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cardiovascular Diseases; Dogs; Hemodynamics; Propanolamines | 1986 |
Milrinone and thyroid hormone stimulate myocardial membrane Ca2+-ATPase activity and share structural homologies.
Topics: Aminopyridines; Amrinone; Animals; Calcimycin; Calcium-Transporting ATPases; Erythrocytes; Female; Male; Milrinone; Myocardium; Pyridones; Rabbits; Sarcolemma; Structure-Activity Relationship; Sulfonamides; Thyroxine; Triiodothyronine; Vanadium | 1985 |
[New cardiotonic agents].
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Colforsin; Deoxyepinephrine; Humans; Imidazoles; Levodopa; Milrinone; Practolol; Prenalterol; Propanolamines; Pyridones; Quinazolines; Xamoterol | 1985 |
New positive inotropic drugs for the treatment of congestive heart failure.
Topics: Aminopyridines; Amrinone; Cardiac Output; Cardiotonic Agents; Dipeptides; Dobutamine; Enalapril; Heart Failure; Humans; Milrinone; Myocardial Contraction; Pyridones; Stimulation, Chemical; Vascular Resistance; Vasodilator Agents | 1985 |
Enhanced relaxation and reduced positive inotropic effects of amrinone in ventricular muscle from cats with subacute heart failure. Implications for drug therapy.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Cats; Cyclic AMP; Heart Failure; Heart Ventricles; Isoproterenol; Myocardial Contraction; Potassium | 1985 |
Influence of calcium and calcium-modulating agents on differentiation of murine erythroleukaemia cells.
Topics: 4-Aminopyridine; Aminopyridines; Amrinone; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Egtazic Acid; Erythrocytes; Erythropoiesis; Friend murine leukemia virus; Gallic Acid; Leukemia, Erythroblastic, Acute; Mice; Razoxane; Verapamil | 1985 |
Differential inhibition of cardiac cyclic nucleotide phosphodiesterase isozymes by cardiotonic drugs.
Topics: Aminopyridines; Amrinone; Animals; Antibodies, Monoclonal; Cardiotonic Agents; Cattle; Cyclic GMP; Enoximone; Imidazoles; Isoenzymes; Mice; Milrinone; Myocardium; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Pyridones; Rabbits | 1986 |
Inotropic effects of amrinone and milrinone on contraction and relaxation of isolated cardiac muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cats; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Humans; Hypoxia; Milrinone; Myocardial Contraction; Oxygen; Pyridones; Ranidae; Rats; Sarcoplasmic Reticulum; Stimulation, Chemical; Temperature; Time Factors | 1986 |
The inotropic effects of amrinone and milrinone on neonatal and young canine cardiac muscle.
Topics: Age Factors; Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cyclic AMP; Dogs; Heart; Lactates; Lactic Acid; Milrinone; Myocardial Contraction; Pyridones; Time Factors | 1986 |
Effects of amrinone and milrinone on calcium influx into the myocardium.
Topics: Aminopyridines; Amrinone; Animals; Calcium; Cattle; Cyclic AMP; Guinea Pigs; Milrinone; Myocardial Contraction; Myocardium; Purkinje Fibers; Pyridones; Rabbits; Rats; Sodium; Time Factors | 1986 |
Relative contribution of inotropic and vasodilator effects to amrinone-induced hemodynamic improvement in congestive heart failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Cardiac Output; Cardiotonic Agents; Female; Heart; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Nitroprusside; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Stroke Volume; Vascular Resistance; Vasodilation | 1986 |
Studies aimed at elucidating the mechanism of action of CI-914, a new cardiotonic agent.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dogs; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Mitochondria, Heart; Myocardial Contraction; Myocardium; Ouabain; Papaverine; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridazines; Rabbits; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase; Theophylline | 1985 |
Isolation and characterization of bovine cardiac muscle cGMP-inhibited phosphodiesterase: a receptor for new cardiotonic drugs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Amrinone; Animals; Antibodies, Monoclonal; Cardiotonic Agents; Cattle; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Cyclic GMP; Enoximone; Imidazoles; Immune Sera; Kinetics; Mice; Mice, Inbred BALB C; Milrinone; Molecular Weight; Myocardium; Phosphodiesterase Inhibitors; Phosphorylation; Pyridones | 1986 |
Cardiotonic and coronary vasodilatatory effects of amrinone in the canine heart-lung preparation with a support dog as compared with those of dobutamine.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Coronary Circulation; Cyclic AMP; Dobutamine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Vasodilator Agents | 1986 |
The in vitro effect of amrinone on platelet aggregation in human whole blood.
Topics: Adenosine Diphosphate; Aminopyridines; Amrinone; Arachidonic Acid; Arachidonic Acids; Collagen; Humans; In Vitro Techniques; Male; Platelet Aggregation; Thromboxane A2 | 1986 |
Comparison of some new positive inotropic agents in guinea pigs.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Dose-Response Relationship, Drug; Enoximone; Guinea Pigs; Heart Rate; Hydralazine; Imidazoles; Isoproterenol; Male; Myocardial Contraction; Ouabain; Vasodilation | 1985 |
Effects of amrinone on myocardial energetics in severe congestive heart failure.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Coronary Circulation; Dogs; Enoximone; Heart; Heart Failure; Humans; Imidazoles; Isoproterenol; Milrinone; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphodiesterase Inhibitors; Pyridones | 1985 |
Comparative immediate hemodynamic and hormonal effects of amrinone and captopril in patients with severe chronic heart failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Captopril; Cardiac Output; Cardiotonic Agents; Female; Follow-Up Studies; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Renin; Renin-Angiotensin System; Time Factors; Vascular Resistance | 1986 |
Historical perspectives on inotropic agents.
Topics: Alkaloids; Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Catecholamines; Cats; Digitalis; Digitalis Glycosides; Dogs; Europe; Glucagon; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Milrinone; Plants, Medicinal; Plants, Toxic; Pyridones; Ranidae; United States | 1986 |
[The mutagenicity of Cordemcura].
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; DNA Repair; Mutagenicity Tests; Mutagens; Proteus mirabilis; Rats | 1986 |
Bipyridine cardiotonics: the three-dimensional structures of amrinone and milrinone.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Crystallography; Dogs; Magnetic Resonance Spectroscopy; Milrinone; Models, Molecular; Myocardial Contraction; Pyridones; X-Ray Diffraction | 1986 |
Interaction of amrinone with endogenous adenosine in guinea-pig atria.
Topics: Adenosine; Adenosine Deaminase; Aminopyridines; Amrinone; Animals; Cardiac Glycosides; Cardiotonic Agents; Dipyridamole; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Reserpine; Theophylline | 1986 |
[The synthesis of 3-amino-5-(4-pyridinyl)-1,2-dihydropyrid-2-one (Cordemcura) from a technical mixture of pyridines].
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Chemical Phenomena; Chemistry; Pyridines | 1986 |
[The purification and characterization of Cordemcura].
Topics: Aminopyridines; Amrinone; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Mass Spectrometry; Solubility; Spectrophotometry, Ultraviolet | 1986 |
[Cardiac effects of Cordemcura in vitro].
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Myocardial Contraction; Stimulation, Chemical | 1986 |
[The action of Cordemcura on the energy balance of the isolated rabbit heart].
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Dopamine; Energy Metabolism; Heart; Heart Rate; In Vitro Techniques; Male; Myocardium; Oxygen Consumption; Perfusion; Rabbits | 1986 |
[Modification of smooth muscle contractility by Cordemcura].
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains | 1986 |
[The cardiovascular effect of Cordemcura on various animal models in vivo].
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Cats; Dopamine; Heart Rate; Hemodynamics; Male; Rats; Species Specificity; Swine; Vascular Resistance | 1986 |
[Comparison of the action of Cordemcura on selected cardiovascular parameters following intraduodenal and intravenous application in beagles].
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Duodenum; Heart Rate; Hemodynamics; Injections, Intravenous; Time Factors; Vascular Resistance | 1986 |
[Comparison of the cardiovascular actions of Cordemcura, isoprenaline and dobutamine in cats].
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Dobutamine; Dose-Response Relationship, Drug; Hemodynamics; Isoproterenol | 1986 |
[Spectrum of the adverse effects of Cordemcura].
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Diuresis; Guinea Pigs; Heart Rate; Male; Mice; Rats; Rats, Inbred Strains; Vasodilation | 1986 |
[Acute and subacute toxicity of Cordemcura].
Topics: Administration, Oral; Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Injections, Intravenous; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Time Factors | 1986 |
[Chronic toxicity testing of Cordemcura].
Topics: Aminopyridines; Amrinone; Animals; Body Weight; Cardiotonic Agents; Female; Male; Organ Size; Platelet Count; Rats; Rats, Inbred Strains | 1986 |
[Subchronic toxicity testing of Cordemcura in the mini-Lewe minipig].
Topics: Aminopyridines; Amrinone; Animals; Blood Cell Count; Body Weight; Cardiotonic Agents; Female; Male; Sex Factors; Swine; Swine, Miniature | 1986 |
[The effect of Cordemcura on the prenatal development of the rat].
Topics: Aminopyridines; Amrinone; Animals; Body Weight; Bone and Bones; Cardiotonic Agents; Eating; Embryo Implantation; Embryonic and Fetal Development; Female; Fetal Resorption; Fetus; Pregnancy; Rats; Rats, Inbred Strains | 1986 |
Myocardial pharmacodynamics of dopamine, dobutamine, amrinone and isoprenaline compared in the isolated rabbit heart.
Topics: Aminopyridines; Amrinone; Animals; Coronary Circulation; Dobutamine; Dopamine; Female; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Rabbits | 1986 |
The binding of amrinone to plasma proteins.
Topics: Aminopyridines; Amrinone; Blood Proteins; Humans; Protein Binding | 1986 |
Dose-related cardiovascular effects of amrinone during enflurane anesthesia in the dog.
Topics: Aminopyridines; Amrinone; Anesthesia, Inhalation; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enflurane; Female; Heart Rate; Hemodynamics; Male; Vascular Resistance | 1986 |
Effect of amrinone on right ventricular function: predominance of afterload reduction.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Nitroprusside; Stroke Volume; Vascular Resistance | 1986 |
Additive effects of dobutamine and amrinone on myocardial contractility and ventricular performance in patients with severe heart failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Dobutamine; Drug Synergism; Female; Heart Failure; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Contraction; Stroke Volume | 1986 |
Augmentation of cardiac function in end-stage heart failure by combined use of dobutamine and amrinone.
Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Cardiotonic Agents; Dobutamine; Drug Therapy, Combination; Hemodynamics; Humans; Male; Middle Aged | 1986 |
Ligand-receptor interactions via hydrogen-bond formation. Synthesis and pharmacological evaluation of pyrrolo and pyrido analogues of the cardiotonic agent 7-hydroxycyclindole.
Topics: Aminopyridines; Amrinone; Animals; Carbazoles; Cardiotonic Agents; Cats; Heart; Myocardial Contraction; Stimulation, Chemical; Structure-Activity Relationship | 1986 |
New positive inotropic agents for congestive heart failure.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Drug Evaluation; Heart Failure; Humans; Milrinone; Pyridones | 1986 |
The in vitro effect of amrinone on thromboxane B2 synthesis in human whole blood.
Topics: 6-Ketoprostaglandin F1 alpha; Aminopyridines; Amrinone; Blood Cells; Collagen; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kinetics; Thromboxane B2 | 1986 |
[Comparison of the electrocardiographic effects of equipotent inotropic doses of amrinone and ouabain in isolated hearts of guinea pigs].
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Electrocardiography; Guinea Pigs; Heart Rate; Myocardial Contraction; Ouabain | 1985 |
Effects of amrinone on the contractile behaviour of frog striated muscle fibres.
Topics: Aminopyridines; Amrinone; Animals; Caffeine; Calcium; Computers; Electric Stimulation; In Vitro Techniques; Kinetics; Models, Biological; Muscle Contraction; Muscles; Myosins; Rana temporaria | 1985 |
[Amrinone in acute and long-term therapy].
Topics: Administration, Oral; Aminopyridines; Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Disease; Exercise Test; Half-Life; Heart Failure; Hemodynamics; Humans; Injections, Intravenous; Long-Term Care | 1985 |
Alternative to the digitalis glycosides for heart failure.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Digitalis Glycosides; Heart Failure; Humans | 1985 |
The effects of amrinone on human platelet aggregation: evidence that amrinone does not act through a cyclic nucleotide mechanism in platelet rich plasma.
Topics: Adenosine Diphosphate; Aminopyridines; Amrinone; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Humans; Nucleotides, Cyclic; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H | 1985 |
Effects of amrinone on contraction and K+-induced contracture of normal and subacutely failed cat ventricular muscle.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Heart Failure; Hemodynamics; Isoproterenol; Myocardial Contraction; Nadolol; Ouabain; Potassium; Propanolamines | 1986 |
Does amrinone inhibition of stimulated bone resorption involve Na+-Ca++ exchange?
Topics: Aminopyridines; Amrinone; Animals; Bone Resorption; Calcium; Cardiotonic Agents; Cycloheximide; Dactinomycin; Hydroxyurea; In Vitro Techniques; Ion Exchange; Leucine; Mice; Parathyroid Hormone; Rats; Rats, Inbred Strains; Sodium; Thymidine; Uridine | 1986 |
The effects of amrinone and related drugs on intracellular calcium in isolated mammalian cardiac and vascular smooth muscle.
Topics: Actin Cytoskeleton; Aequorin; Aminopyridines; Amrinone; Animals; Caffeine; Calcium; Cats; Dose-Response Relationship, Drug; Female; Ferrets; Isoproterenol; Male; Muscle, Smooth, Vascular; Myocardium; Time Factors | 1986 |
Chronic congestive heart failure. Where have we been? Where are we heading?
Topics: Aminopyridines; Amrinone; Biopsy; Calcium Channel Blockers; Cardiology; Chronic Disease; Digitalis; Dobutamine; Dopamine; Forecasting; Heart Failure; Hemodynamics; Humans; Infusions, Parenteral; Myocardial Contraction; Myocardium; Plants, Medicinal; Plants, Toxic; Prognosis; Quality of Life; Vasodilator Agents | 1986 |
The effects of two new inotropic agents on microsomal liver function in patients with congestive heart failure.
Topics: Adult; Aged; Aminopyridines; Aminopyrine; Amrinone; Breath Tests; Cardiac Output; Cardiotonic Agents; Heart Failure; Humans; Liver; Liver Function Tests; Male; Microsomes, Liver; Middle Aged; Milrinone; Pyridones | 1986 |
Amrinone effects on electromechanical coupling and depolarization-induced automaticity in ventricular muscle of guinea pigs and ferrets.
Topics: Action Potentials; Aminopyridines; Amrinone; Animals; Ferrets; Guinea Pigs; Heart; Membrane Potentials; Myocardial Contraction; Receptors, Histamine; Stimulation, Chemical | 1985 |
Intravenous amrinone: an advance or a wrong step?
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Heart Failure; Humans; Infusions, Parenteral; Vasodilator Agents | 1985 |
Amrinone after cardiopulmonary bypass surgery. A case report.
Topics: Adult; Aminopyridines; Amrinone; Aortic Valve; Blood Pressure; Cardiopulmonary Bypass; Cardiotonic Agents; Female; Heart Valve Diseases; Heart Valve Prosthesis; Humans; Intraoperative Complications | 1985 |
[Dose-dependent effect of amrinone on hemodynamics, myocardial circulation and myocardial energy requirement. An experimental study].
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Energy Metabolism; Female; Heart Rate; Hemodynamics; Male; Myocardium; Oxygen Consumption; Stroke Volume; Vascular Resistance | 1985 |
Clinical effects and side effects of amrinone. A study of 24 patients with chronic congestive heart failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiotonic Agents; Chronic Disease; Electrocardiography; Exercise Test; Female; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Radionuclide Imaging; Stroke Volume | 1985 |
Effects of intracoronary and intravenous amrinone infusions in patients with cardiac failure and patients with near normal cardiac function.
Topics: Adult; Aminopyridines; Amrinone; Angina Pectoris; Blood Pressure; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Circulation; Heart Failure; Hemodynamics; Humans; Infusions, Intra-Arterial; Infusions, Parenteral; Lactates; Male; Middle Aged; Vascular Resistance | 1985 |
Concentration-response curves of positive inotropic agents before and after ouabain pretreatment.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Male; Metaproterenol; Myocardial Contraction; Ouabain; Papillary Muscles; Phenylephrine; Stimulation, Chemical; Theophylline | 1985 |
[Effects of amrinone on hemodynamics, oxygen consumption and plasma catecholamine levels in anesthetized dogs].
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Catecholamines; Dogs; Hemodynamics; Oxygen Consumption | 1985 |
A symposium: Amrinone. Introduction.
Topics: Aminopyridines; Amrinone; Diuretics; Heart Failure; Humans; Vasodilator Agents | 1985 |
A symposium: Amrinone. November 11, 1984, Miami, Florida.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Heart Diseases; Humans | 1985 |
Comparative vasoactive therapy for heart failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Cardiotonic Agents; Catecholamines; Dobutamine; Dopamine; Female; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Pulmonary Wedge Pressure; Tachycardia; Vascular Resistance | 1985 |
Electrophysiologic effects of amrinone.
Topics: Adult; Aged; Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiac Output; Cardiac Pacing, Artificial; Cardiotonic Agents; Electrocardiography; Electrophysiology; Female; Heart Conduction System; Heart Failure; Humans; Male; Middle Aged | 1985 |
Pathophysiology of cardiac failure.
Topics: Aminopyridines; Amrinone; Blood Pressure; Cardiac Output; Cardiotonic Agents; Dobutamine; Dopamine; Furosemide; Heart; Heart Failure; Humans; Myocardial Contraction; Nitroprusside; Norepinephrine; Oxygen Consumption; Vascular Resistance; Vasoconstriction | 1985 |
Amrinone in the management of low cardiac output after open heart surgery.
Topics: Adult; Aged; Aminopyridines; Amrinone; Cardiac Output; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Female; Heart Failure; Humans; Male; Middle Aged; Postoperative Complications; Pulmonary Wedge Pressure; Shock, Cardiogenic; Time Factors; Vascular Resistance | 1985 |
Intravenous amrinone.
Topics: Aminopyridines; Amrinone; Arrhythmias, Cardiac; Cardiotonic Agents; Humans; Infusions, Parenteral | 1985 |
The beneficial effect of amrinone on acute drug-induced heart failure in the anaesthetised dog.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Central Venous Pressure; Dogs; Female; Heart Failure; Male; Pentobarbital; Procainamide; Propranolol; Vascular Resistance; Verapamil | 1985 |
Hemodynamic consequences of inotropic support with digoxin or amrinone in lambs with ventricular septal defect.
Topics: Aminopyridines; Amrinone; Animals; Animals, Newborn; Digoxin; Dose-Response Relationship, Drug; Heart Septal Defects, Ventricular; Hemodynamics; Myocardial Contraction; Sheep; Time Factors | 1985 |
Assessment of amrinone.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Humans | 1985 |
[Effect of amrinone on hemodynamics, oxygen consumption and plasma catecholamine levels in endotoxin injected dogs].
Topics: Aminopyridines; Amrinone; Animals; Catecholamines; Coronary Circulation; Dogs; Oxygen Consumption; Shock, Septic | 1985 |
[Amrinone in catecholamine refractory heart failure in septic shock].
Topics: Adult; Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Catecholamines; Dose-Response Relationship, Drug; Drug Resistance; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Respiratory Insufficiency; Shock, Septic | 1985 |
Molecular basis for the cardiovascular activities of amrinone and AR-L57.
Topics: Aminopyridines; Amrinone; Animals; Calcium; Carbachol; Cardiotonic Agents; Cats; Erythrocytes; Female; Guinea Pigs; Heart; Imidazoles; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phosphoric Diester Hydrolases; Phosphorylases; Protein Kinases; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1984 |
Competitive inhibition of phosphodiesterase activity by amrinone: its implication in the cardiac effect of the drug.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Amrinone; Animals; Calcium Chloride; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Magnesium; Muscle Proteins; Myocardial Contraction; Ouabain; Phosphodiesterase Inhibitors | 1984 |
Excitatory and inhibitory actions of amrinone on the guinea-pig isolated ileum and vas deferens.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Drug Interactions; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Vas Deferens | 1982 |
Clinical studies with beta 2 adrenoceptor agonists in heart failure.
Topics: Adrenergic beta-Agonists; Albuterol; Aminopyridines; Amrinone; Cardiotonic Agents; Ethanolamines; Heart Failure; Hemodynamics; Humans; Middle Aged; Myocardial Infarction | 1982 |
[New cardiotonic agents].
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiotonic Agents; Heart Diseases; Humans; Phosphodiesterase Inhibitors | 1983 |
Inotropic drugs in the treatment of heart failure.
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiac Glycosides; Cardiotonic Agents; Cyclic AMP; Heart Failure; Humans; Imidazoles; Ion Channels; Myocardial Contraction; Phosphodiesterase Inhibitors; Receptors, Adrenergic, alpha | 1984 |
Hemodynamic and regional blood flow distribution responses to dextran, hydralazine, isoproterenol and amrinone during experimental cardiac tamponade.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Blood Volume; Cardiac Output; Cardiac Tamponade; Cardiotonic Agents; Dextrans; Dogs; Female; Heart Rate; Hemodynamics; Hydralazine; Isoproterenol; Male; Microspheres; Radioisotopes; Regional Blood Flow; Stroke Volume; Vascular Resistance | 1983 |
Inotropic drugs of the future.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Heart Failure; Humans; Imidazoles; Practolol; Prenalterol; Propanolamines; Xamoterol | 1982 |
Differential effects of amrinone on contractility and taurine influx in rat and guinea pig hearts.
Topics: Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Guinea Pigs; Heart; Kinetics; Male; Myocardial Contraction; Myocardium; Perfusion; Rats; Species Specificity; Taurine | 1980 |
The effects of amrinone on transport and cyclic AMP metabolism in toad urinary bladder.
Topics: Aminopyridines; Amrinone; Animals; Biological Transport; Bufonidae; Cyclic AMP; Epithelium; Female; Osmolar Concentration; Permeability; Phosphoric Diester Hydrolases; Protein Kinases; Urea; Urinary Bladder; Water-Electrolyte Balance | 1981 |
Involvement of cyclic AMP in the direct inotropic action of amrinone. Biochemical and functional evidence.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Amrinone; Animals; Carbachol; Cyclic AMP; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Myocardium; Papillary Muscles | 1981 |
Positive inotropic effect of amrinone in relation to cyclic nucleotide metabolism in the canine ventricular muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Amrinone; Animals; Carbachol; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Dogs; Drug Interactions; Female; In Vitro Techniques; Isoproterenol; Male; Myocardium; Time Factors | 1982 |
[New inotropic drugs].
Topics: Aminopyridines; Amrinone; Calcium; Cardiotonic Agents; Cyclic AMP; Digitalis Glycosides; Drug Evaluation; Heart Failure; Humans; Phosphodiesterase Inhibitors; Sympathomimetics | 1982 |
Intracellular calcium transients in human working myocardium as detected with aequorin.
Topics: Aequorin; Aminopyridines; Amrinone; Calcium; Culture Techniques; Digitalis Glycosides; Humans; Ion Channels; Isoproterenol; Luminescent Proteins; Myocardial Contraction; Myocardium; Papillary Muscles; Theophylline; Time Factors | 1984 |
Correction of dilutional hyponatremia in severe chronic heart failure by converting-enzyme inhibition.
Topics: Adult; Aged; Aminopyridines; Amrinone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiotonic Agents; Female; Heart Failure; Hemodynamics; Humans; Hydralazine; Hyponatremia; Male; Middle Aged; Prazosin; Proline | 1984 |
Inotropic drugs for treatment of the failing heart.
Topics: Aminophylline; Aminopyridines; Amrinone; Cardiotonic Agents; Catecholamines; Digitalis Glycosides; Glucagon; Heart Failure; Hemodynamics; Humans; Milrinone; Myocardial Contraction; Pyridones; Receptors, Adrenergic, beta; Theophylline | 1984 |
In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, in various animals.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Cats; Dobutamine; Dogs; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phentolamine; Pindolol; Pyrazines; Quinolines; Rabbits; Rats; Sodium-Potassium-Exchanging ATPase; Theophylline | 1984 |
Amrinone therapy in patients with heart failure. Lack of improvement in functional capacity and left ventricular function at rest and during exercise.
Topics: Administration, Oral; Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Cerebral Ventriculography; Drug Evaluation; Echocardiography; Electrocardiography; Heart Failure; Heart Function Tests; Heart Rate; Humans; Male; Middle Aged; Oxygen Consumption; Physical Exertion; Radionuclide Imaging | 1984 |
[Alternatives to digitalis therapy].
Topics: Aminopyridines; Amrinone; Captopril; Catecholamines; Diuretics; Heart Failure; Humans; Hydralazine; Nitrates; Nitroprusside; Practolol; Prazosin; Prenalterol; Vasodilator Agents | 1983 |
Hemodynamic and clinical limitations of long-term inotropic therapy with amrinone in patients with severe chronic heart failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Cardiac Output; Chronic Disease; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Contraction; Renin; Stroke Volume; Time Factors; Vasodilator Agents | 1984 |
Amrinone: a promising new cardiotonic agent in the treatment of chronic cardiac failure.
Topics: Activities of Daily Living; Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Chronic Disease; Dose-Response Relationship, Drug; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Long-Term Care; Male; Middle Aged; Myocardial Contraction; Oxygen Consumption | 1983 |
Improvement in exercise capacity despite cardiac deteriora tion: nonivasive assessment of long-term therapy with amrinone in severe heart failure.
Topics: Adult; Aminopyridines; Amrinone; Cardiotonic Agents; Exercise Test; Female; Follow-Up Studies; Heart Failure; Humans; Long-Term Care; Male; Middle Aged; Stroke Volume | 1983 |
Hemodynamic effects of amrinone in dogs anesthetized with halothane: comparison with isoproterenol and dobutamine.
Topics: Aminopyridines; Amrinone; Anesthesia, Inhalation; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Catecholamines; Dobutamine; Dogs; Female; Halothane; Hemodynamics; Infusions, Parenteral; Isoproterenol; Male; Pulmonary Artery; Vascular Resistance | 1984 |
Amrinone: acute electrophysiologic and hemodynamic effects in patients with congestive heart failure.
Topics: Adult; Aminopyridines; Amrinone; Atrioventricular Node; Cardiotonic Agents; Electrocardiography; Female; Heart Failure; Hemodynamics; Humans; Infusions, Parenteral; Male; Middle Aged; Pulmonary Wedge Pressure; Tachycardia; Vascular Resistance | 1984 |
Amrinone: a weaning agent in catecholamine dependence.
Topics: Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Catecholamines; Female; Humans; Myocardial Infarction; Substance-Related Disorders | 1984 |
Pulmonary vasodilator therapy in persistent pulmonary hypertension of the newborn.
Topics: Acetylcholine; Aminopyridines; Amrinone; Bradykinin; Chlorpromazine; Humans; Infant, Newborn; Isoproterenol; Lung; Nitroprusside; Persistent Fetal Circulation Syndrome; Prostaglandins; Tolazoline; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 1984 |
Dual effects of amrinone and caffeine on cardiac contractility: positive versus negative inotropy.
Topics: Action Potentials; Aminopyridines; Amrinone; Animals; Caffeine; Cardiotonic Agents; Ferrets; In Vitro Techniques; Myocardial Contraction; Papillary Muscles | 1984 |
Failure of low doses of amrinone to produce sustained hemodynamic improvement in patients with severe chronic congestive heart failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Cardiotonic Agents; Chronic Disease; Dose-Response Relationship, Drug; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Pulmonary Wedge Pressure; Vascular Resistance | 1984 |
Electromechanical dissociation and possible uncoupling of phosphorylation following tachydysrhythmogenic dose of amrinone in the guinea-pig Langendorff heart preparation.
Topics: Aminopyridines; Amrinone; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Electrocardiography; Guinea Pigs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardium; Oxidative Phosphorylation; Time Factors; Uncoupling Agents; Verapamil | 1984 |
Echocardiographic evaluation of cardiovascular effects of amrinone.
Topics: Adult; Aminopyridines; Amrinone; Cardiac Catheterization; Cardiomyopathy, Dilated; Cardiotonic Agents; Echocardiography; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction | 1984 |
Assessment of the inotropic and vasodilator effects of amrinone versus isoproterenol.
Topics: Aminopyridines; Amrinone; Blood Pressure; Cardiac Catheterization; Cardiac Output; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Humans; Isoproterenol; Pulmonary Wedge Pressure; Stroke Volume; Vascular Resistance; Vasodilator Agents | 1984 |
Inotropic effect of amrinone in rabbit papillary muscle: reversal of the myocardial depressant effect of halothane.
Topics: Aminopyridines; Amrinone; Animals; Anti-Arrhythmia Agents; Electric Stimulation; Halothane; In Vitro Techniques; Muscle Contraction; Papillary Muscles; Rabbits | 1984 |
[Right ventricular hemodynamics and lung function following amrinone injection].
Topics: Airway Resistance; Aminopyridines; Amrinone; Cardiotonic Agents; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Lung Diseases, Obstructive; Lung Volume Measurements; Myocardial Contraction | 1984 |
Positive inotropic effect of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212) in the dog with experimentally-induced right-sided heart failure.
Topics: Administration, Oral; Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Dobutamine; Dogs; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Injections, Intravenous; Male; Myocardial Contraction; Pyrazines; Quinolines | 1984 |
Mechanism of action of amrinone: role of thromboxane synthetase inhibition.
Topics: 6-Ketoprostaglandin F1 alpha; Aminopyridines; Amrinone; Animals; Blood Platelets; Cardiotonic Agents; Humans; In Vitro Techniques; Male; Oxidoreductases; Rabbits; Thromboxane B2; Thromboxane-A Synthase | 1983 |
Responses of isolated dog arteries to amrinone.
Topics: Adenosine; Aminopyridines; Amrinone; Animals; Arteries; Calcium; Cardiotonic Agents; Dinoprost; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Prostaglandins F | 1984 |
Effects of amrinone on twitch, tetanus and force-velocity relationship in frog skeletal muscle.
Topics: Aminopyridines; Amrinone; Animals; Energy Metabolism; Isometric Contraction; Muscle Contraction; Muscles; Rana temporaria | 1984 |
Pulmonary vascular effects of amrinone in conscious lambs.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Female; Hypoxia; Male; Propranolol; Pulmonary Circulation; Sheep; Vascular Resistance; Vasodilation | 1983 |
Amrinone-mediated thrombocytopenia.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Heart Failure; Humans; Platelet Count; Thrombocytopenia | 1983 |
Developmental changes in the interactions of amrinone and ouabain in canine ventricular muscle.
Topics: Aminopyridines; Amrinone; Animals; Animals, Newborn; Cardiotonic Agents; Dogs; Drug Interactions; In Vitro Techniques; Myocardial Contraction; Ouabain | 1983 |
Effect of amrinone on sodium-calcium exchange in cardiac sarcolemmal vesicles.
Topics: Aminopyridines; Amrinone; Animals; Calcium; Calcium Radioisotopes; Cardiotonic Agents; Guinea Pigs; Heart; In Vitro Techniques; Male; Muscle Proteins; Myocardium; Rats; Rats, Inbred Strains; Sarcolemma; Sodium; Species Specificity | 1983 |
Comparative actions of hydralazine, nifedipine and amrinone in primary pulmonary hypertension.
Topics: Adult; Aminopyridines; Amrinone; Cardiac Catheterization; Cardiac Output; Female; Humans; Hydralazine; Hypertension, Pulmonary; Male; Middle Aged; Nifedipine; Pulmonary Wedge Pressure; Stroke Volume; Vascular Resistance; Vasodilator Agents | 1983 |
Electrocardiographic changes induced by amrinone in the isolated perfused guinea-pig Langendorff heart preparation.
Topics: Aminopyridines; Amrinone; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Electrocardiography; Guinea Pigs; Heart; Heart Conduction System; Heart Rate; In Vitro Techniques; Time Factors | 1983 |
Side effects of amrinone therapy.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Humans; In Vitro Techniques; Myocardial Contraction; Stimulation, Chemical | 1983 |
Effects of amrinone on the transmembrane action potential of rabbit sinus node pacemaker cells.
Topics: Action Potentials; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Female; Heart Conduction System; In Vitro Techniques; Male; Pindolol; Rabbits; Verapamil | 1983 |
Amrinone in severe congestive heart failure: another look at an intriguing new cardioactive drug.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Cardiac Output; Cardiotonic Agents; Dobutamine; Dose-Response Relationship, Drug; Female; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Stroke Volume; Time Factors; Vascular Resistance | 1984 |
Amrinone in the treatment of chronic cardiac failure.
Topics: Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Chronic Disease; Double-Blind Method; Drug Evaluation; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Outpatients; Oxygen Consumption; Random Allocation | 1984 |
Amrinone-induced thrombocytopenia.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Platelets; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Immunoglobulin G; Indium; Male; Middle Aged; Platelet Count; Prospective Studies; Radioisotopes; Thrombocytopenia | 1984 |
The effects of amrinone on platelet count, survival and function in patients with congestive cardiac failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Platelets; Cardiotonic Agents; Cell Survival; Female; Heart Failure; Humans; Male; Middle Aged; Platelet Count; Prospective Studies | 1984 |
Non-additive positive inotropic effects of amrinone and ouabain on cat papillary muscles.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Dose-Response Relationship, Drug; Female; Male; Ouabain; Papillary Muscles; Stimulation, Chemical | 1984 |
Dangers of amrinone.
Topics: Aminopyridines; Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Heart Failure; Humans | 1984 |
Inotropic and vasodilator effects of amrinone on isolated human tissue.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Defects, Congenital; Heart Valve Diseases; Humans; In Vitro Techniques; Myocardial Contraction; Umbilical Arteries; Vasodilation | 1984 |
Comparison of the effects of amrinone and sodium nitroprusside on haemodynamics, contractility, and myocardial metabolism in patients with cardiac failure due to coronary artery disease and dilated cardiomyopathy.
Topics: Adult; Aminopyridines; Amrinone; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Disease; Female; Ferricyanides; Heart; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Myocardium; Nitroprusside | 1984 |
Effect of oral amrinone on platelet function and survival.
Topics: Administration, Oral; Adult; Aminopyridines; Amrinone; Blood Platelets; Cardiotonic Agents; Cell Survival; Humans; Middle Aged; Thrombocytopenia | 1984 |
Effects of amrinone on experimental acute myocardial ischaemic injury.
Topics: Aminopyridines; Amrinone; Animals; Carbon Dioxide; Cardiotonic Agents; Dogs; Electrocardiography; Hemodynamics; Isoproterenol; Myocardial Infarction; Myocardium | 1980 |
Effect of Amrinone, a cardiotonic drug, on hemodynamics and platelet function.
Topics: Adenosine Diphosphate; Adult; Aminopyridines; Amrinone; Animals; Arachidonic Acids; Blood Pressure; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Heart Rate; Hemodynamics; Humans; Platelet Aggregation; Platelet Count; Prostaglandin-Endoperoxide Synthases; Thromboxane B2 | 1981 |
Haemodynamic effects of intravenous amrinone in patients with impaired left ventricular function.
Topics: Adult; Aminopyridines; Amrinone; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction | 1983 |
Amrinone--promising innovation for treatment of the failing heart.
Topics: Aminopyridines; Amrinone; Heart Failure; Humans; Kinetics; Myocardial Contraction; Stimulation, Chemical | 1983 |
Side effects of amrinone therapy.
Topics: Administration, Oral; Adult; Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Female; Heart Failure; Humans; Hypotension; Infusions, Parenteral; Male; Middle Aged; Thrombocytopenia | 1983 |
Adverse effects of long-term amrinone administration in congestive heart failure.
Topics: Abdomen; Aged; Aminopyridines; Amrinone; Cough; Heart Failure; Humans; Liver Function Tests; Male; Middle Aged; Nausea; Pain; Time Factors; Vomiting | 1983 |
Amrinone therapy in congestive cardiomyopathy.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Female; Heart Failure; Humans; Middle Aged | 1983 |
Haemodynamic effects of intravenous amrinone in patients with impaired left ventricular function.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Contrast Media; Heart Diseases; Hemodynamics; Humans | 1983 |
Developmental changes in the cardiac effects of amrinone in the dog.
Topics: Aging; Aminopyridines; Amrinone; Animals; Animals, Newborn; Dogs; Female; Heart Conduction System; Male; Muscle Contraction; Muscle Development; Myocardial Contraction; Papillary Muscles; Purkinje Fibers | 1983 |
Amrinone dilates pulmonary vessels and blunts hypoxic vasoconstriction in isolated rat lungs.
Topics: Aminopyridines; Amrinone; Angiotensin II; Animals; Blood Pressure; In Vitro Techniques; Male; Meclofenamic Acid; Oxygen; Pulmonary Artery; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilator Agents; Vasomotor System | 1983 |
Amrinone relaxing effect on the isolated guinea pig trachea and its interaction with aminophylline.
Topics: Aminophylline; Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea | 1983 |
Dose proportionality of amrinone.
Topics: Adult; Aminopyridines; Amrinone; Dose-Response Relationship, Drug; Half-Life; Humans; Kinetics; Male | 1983 |
The effects of amrinone on cardiac function, oxygen consumption and lactate production of an isolated, perfused, working guinea-pig heart.
Topics: Aminopyridines; Amrinone; Animals; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Guinea Pigs; Heart; In Vitro Techniques; Lactates; Lactic Acid; Myocardium; Oxygen Consumption; Stroke Volume | 1983 |
Effects of amrinone on atrioventricular conduction in the intact canine heart.
Topics: Aminopyridines; Amrinone; Animals; Bundle of His; Cardiotonic Agents; Dogs; Heart Conduction System; Ouabain; Propranolol; Sinoatrial Node; Verapamil | 1983 |
Oral bioavailability and intravenous pharmacokinetics of amrinone in humans.
Topics: Administration, Oral; Aminopyridines; Amrinone; Biological Availability; Half-Life; Humans; Injections, Intravenous; Kinetics; Male | 1983 |
[Experimental and clinical pharmacokinetics of amrinone].
Topics: Aminopyridines; Amrinone; Animals; Dose-Response Relationship, Drug; Half-Life; Humans; Kinetics; Rats; Rats, Inbred Strains; Tissue Distribution | 1982 |
Amrinone--a new inotropic agent in chronic resistant congestive cardiac failure.
Topics: Administration, Oral; Aminopyridines; Amrinone; Cardiotonic Agents; Heart Failure; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Contraction; Thrombocytopenia | 1981 |
Long-term amrinone therapy in patients with severe heart failure: drug-dependent hemodynamic benefits despite progression of disease.
Topics: Administration, Oral; Adult; Aminopyridines; Amrinone; Cardiotonic Agents; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Physical Exertion | 1982 |
Inotropic and electrophysiologic effects of amrinone in untreated and digitalized ventricular tissues.
Topics: Aminopyridines; Amrinone; Animals; Digitalis Glycosides; Dogs; Electric Stimulation; Electroencephalography; Female; Heart; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Purkinje Fibers | 1982 |
Cardiotonic agents in the management of chronic cardiac failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Cardiac Output; Cardiotonic Agents; Dobutamine; Ethanolamines; Exercise Test; Female; Heart Failure; Heart Rate; Humans; Kidney Function Tests; Male; Middle Aged; Oxygen Consumption | 1982 |
Acute effects of amrinone on regional myocardial and systemic blood flow distribution in the dog.
Topics: Aminopyridines; Amrinone; Animals; Blood Circulation; Cardiotonic Agents; Cerebrovascular Circulation; Coronary Circulation; Dogs; Female; Hemodynamics; Male | 1982 |
A report on the positive inotropic action of amrinone.
Topics: Aminopyridines; Amrinone; Animals; Calcium; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Myocardial Contraction; Ouabain; Stimulation, Chemical; Temperature; Time Factors | 1982 |
Amrinone activates K+-depolarized atrial and ventricular myocardium of guinea pigs.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Guinea Pigs; Heart Atria; Heart Ventricles; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phentolamine; Potassium; Propranolol; Stimulation, Chemical | 1982 |
Interaction between amrinone and parathyroid hormone on bone in culture.
Topics: Aminopyridines; Amrinone; Animals; Animals, Newborn; Bone and Bones; Bone Resorption; Calcitonin; Cardiotonic Agents; Cells, Cultured; Kinetics; Mice; Nigericin; Ouabain; Parathyroid Hormone | 1982 |
The improvement of cardiac performance by amrinone, a new cardiotonic drug, in an experimental failing heart preparation of the dog.
Topics: Aminopyridines; Amrinone; Animals; Cardiac Output; Cardiotonic Agents; Dogs; Heart Failure; Heart Rate; Myocardial Contraction | 1982 |
Reduction of lethal toxicity of doxorubicin by amrinone.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Doxorubicin; Female; Guinea Pigs; Heart; Heart Atria; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Myocardial Contraction | 1982 |
Acute pharmacodynamics and pharmacokinetics of oral amrinone.
Topics: Administration, Oral; Adult; Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Hemodynamics; Humans; Kinetics; Male; Middle Aged; Time Factors | 1982 |
Clinical experience with amrinone in patients with advanced congestive heart failure.
Topics: Administration, Oral; Aged; Aminopyridines; Amrinone; Cardiotonic Agents; Heart Failure; Humans; Infusions, Parenteral; Middle Aged | 1982 |
Relaxant effects of amrinone upon pulmonary smooth muscle.
Topics: Airway Resistance; Aminophylline; Aminopyridines; Amrinone; Animals; Barium; Calcium; Carbachol; Drug Interactions; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lung; Muscle Relaxation; Muscle, Smooth; Verapamil | 1982 |
Relationship between amrinone plasma concentration and cardiac index.
Topics: Aminopyridines; Amrinone; Cardiac Output; Cardiotonic Agents; Humans; Regression Analysis | 1981 |
Evidence for two separated Ca2+ pathways in smooth muscle plasmalemma.
Topics: Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cell Membrane; Dose-Response Relationship, Drug; Gallopamil; Muscle Contraction; Muscle, Smooth; Norepinephrine; Potassium; Rabbits | 1981 |
Amrinone and exercise performance in patients with chronic heart failure.
Topics: Aminopyridines; Amrinone; Chronic Disease; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Pulmonary Wedge Pressure; Thrombocytopenia | 1981 |
Hemodynamic comparison of intravenous amrinone and dobutamine in patients with chronic congestive heart failure.
Topics: Adolescent; Adult; Aged; Aminopyridines; Amrinone; Cardiac Output; Catecholamines; Chronic Disease; Dobutamine; Female; Heart Failure; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Pulmonary Wedge Pressure; Time Factors | 1981 |
Beneficial effect of amrinone on myocardial oxygen consumption during acute left ventricular failure in dogs.
Topics: Acute Disease; Aminopyridines; Amrinone; Animals; Blood Circulation; Coronary Circulation; Dogs; Female; Heart Failure; Heart Ventricles; Male; Myocardium; Oxygen Consumption | 1981 |
Problems in assessment of new pharmacologic agents for the heart failure patient.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Cardiovascular Agents; Drug Evaluation; Energy Metabolism; Ethanolamines; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardium; Prazosin; Vasodilator Agents | 1981 |
Acute substantial benefit of inotropic therapy with amrinone on exercise hemodynamics and metabolism in severe congestive heart failure.
Topics: Adolescent; Adult; Aminopyridines; Amrinone; Blood Pressure; Exercise Test; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Lactates; Lactic Acid; Male; Middle Aged; Myocardial Contraction; Pulmonary Wedge Pressure; Vascular Resistance | 1981 |
Effects of amrinone on the tracheal musculature and vasculature of the dog.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Isoproterenol; Muscle, Smooth, Vascular; Trachea | 1981 |
High-performance liquid chromatographic analysis of amrinone and its N-acetyl derivative in plasma. Pharmacokinetics of amrinone in the dog.
Topics: Aminopyridines; Amrinone; Animals; Chromatography, High Pressure Liquid; Dogs; Kinetics | 1980 |
Oral amrinone in refractory congestive heart failure.
Topics: Aged; Aminopyridines; Amrinone; Blood Pressure; Coronary Disease; Electrocardiography; Female; Heart Failure; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Radionuclide Imaging; Time Factors | 1980 |
Comments on "cardiotonic activity of amrinone-win 40680 [5-amino-3-4'-bypyridin-6(1H)-one]".
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Chickens; Myocardial Contraction; Rabbits; Rats | 1980 |
Effects of amrinone on myocardial energy metabolism and hemodynamics in patients with severe congestive heart failure due to coronary artery disease.
Topics: Aged; Aminopyridines; Amrinone; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Disease; Electrocardiography; Energy Metabolism; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Myocardium; Oxygen Consumption; Stroke Volume; Vascular Resistance | 1980 |
Effects of amrinone, a cardiotonic drug, on calcium movements in dog erythrocytes.
Topics: Aminopyridines; Amrinone; Animals; Biological Transport; Calcium; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; Extracellular Space; Myocardial Contraction; Sodium; Time Factors | 1980 |
Direct vasodilator and positive inotropic actions of amrinone.
Topics: Aminopyridines; Amrinone; Animals; Calcium Chloride; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Rats; Regional Blood Flow; Species Specificity; Stimulation, Chemical; Vasodilator Agents | 1980 |
Beneficial effects of amrinone-hydralazine combination on resting hemodynamics and exercise capacity in patients with severe congestive heart failure.
Topics: Adult; Aged; Aminopyridines; Amrinone; Blood Pressure; Cardiac Output; Cardiotonic Agents; Drug Therapy, Combination; Exercise Test; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Hydralazine; Male; Middle Aged; Pulmonary Wedge Pressure; Rest; Vascular Resistance | 1981 |
Amrinone metabolism.
Topics: Aminopyridines; Amrinone; Cardiotonic Agents; Dose-Response Relationship, Drug; Half-Life; Humans; Kinetics; Male; Regression Analysis | 1981 |