amrinone and 1-methyl-3-isobutylxanthine

amrinone has been researched along with 1-methyl-3-isobutylxanthine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's6 (37.50)18.2507
2000's3 (18.75)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bristol, JA; Cain, MH; Weishaar, RE1
Abdel-Aleem, S; Badr, M; Frangakis, C1
Himmel, HM; Ravens, U; Schappert, T1
Chiba, S; Horiuchi, A; Iwatsuki, K; Ren, LM1
Meyer, W; Scholz, H1
Ahn, HS; Eardley, D; Prioli, N; Watkins, R1
Earl, CQ; Linden, J; Weglicki, WB1
Kishi, Y; Numano, F1
Greeff, K; Schmitt, M1
Rodger, IW; Shahid, M1
Chiba, S; Iwatsuki, K; Ren, LM1
Azizeh, BY; Houslay, MD; Hruby, VJ; Johnson, DG; Phelps, JR; Trivedi, D; Van Tine, BA1
Sawada, M; Suzumura, A; Takayanagi, T; Tamaru, T; Yoshikawa, M1
Majewski, H; Rechtman, MP; Van der Zypp, A1
Ferrier, GR; Howlett, SE; Moore, HM; Xiong, W1
Bakavoli, M; Hosseini, A; Mansouri, SM; Nick, RS; Parsaee, H; Saberi, MR; Sadeghian, H; Seyedi, SM1

Reviews

1 review(s) available for amrinone and 1-methyl-3-isobutylxanthine

ArticleYear
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity

1985

Other Studies

15 other study(ies) available for amrinone and 1-methyl-3-isobutylxanthine

ArticleYear
Stimulation of fatty acid oxidation in myocytes by phosphodiesterase inhibitors and adenosine analogues.
    Life sciences, 1991, Volume: 48, Issue:18

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Amrinone; Animals; Cells, Cultured; Dipyridamole; Enoximone; Heart; Imidazoles; Milrinone; Myocardium; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Rats

1991
Combined effects of volatile anesthetics and phosphodiesterase inhibitors on contractile performance in guinea pig hearts.
    Anesthesia and analgesia, 1991, Volume: 73, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Depression, Chemical; Guinea Pigs; Halothane; Hemodynamics; In Vitro Techniques; Isoflurane; Male; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridones; Stimulation, Chemical

1991
Effects of the cyclic nucleotide phosphodiesterase inhibitors, rolipram, 3-isobutyl-1-methylxanthine, amrinone and zaprinast, on pancreatic exocrine secretion in dogs.
    European journal of pharmacology, 1991, Dec-10, Volume: 209, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Amrinone; Animals; Bicarbonates; Cyclic AMP; Cyclic GMP; Dogs; Female; Male; Pancreas; Pancreatic Juice; Perfusion; Phosphodiesterase Inhibitors; Proteins; Purinones; Pyrrolidinones; Rolipram; Secretin; Sincalide

1991
Phosphodiesterase-inhibiting properties of newer inotropic agents.
    Circulation, 1986, Volume: 73, Issue:3 Pt 2

    Topics: 1-Methyl-3-isobutylxanthine; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Theophylline

1986
Effects of several newer cardiotonic drugs on cardiac cyclic AMP metabolism.
    Biochemical pharmacology, 1986, Apr-01, Volume: 35, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Colforsin; Cyclic AMP; Enoximone; Guinea Pigs; Hydrolysis; Imidazoles; Isoenzymes; Milrinone; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyridones

1986
Inhibition of cyclic AMP-dependent protein kinase activity by the cardiotonic drugs amrinone and milrinone.
    Life sciences, 1986, Nov-17, Volume: 39, Issue:20

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Amrinone; Animals; Cardiotonic Agents; Cyclic AMP; Dogs; In Vitro Techniques; Milrinone; Muscles; Protein Binding; Protein Kinase C; Protein Kinase Inhibitors; Pyridones

1986
Involvement of cyclic AMP in vasodilatation by amrinone: a comparative study with 3-isobutyl-methyl-xanthine (IBMX).
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Amrinone; Animals; Aorta; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Potassium; Rabbits; Sulfonamides; Theophylline; Vasodilation

1986
Interaction of phosphodiesterase inhibitors triamterene, papaverine, theophylline, IBMX and amrinone with other positive inotropic acting substances on isolated guinea-pig atria.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 287, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Colforsin; Drug Interactions; Electric Stimulation; Guinea Pigs; Heart Rate; Histamine; In Vitro Techniques; Male; Metaproterenol; Myocardial Contraction; Papaverine; Phosphodiesterase Inhibitors; Stimulation, Chemical; Theophylline; Triamterene

1987
Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Carbamates; Cardiovascular Agents; Cyclic AMP; Cyclic GMP; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Rabbits; Theophylline

1989
Effects of cyclic nucleotide phosphodiesterase IV inhibitor, Ro20,1724, on pancreatic exocrine secretion in dog.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amrinone; Analysis of Variance; Animals; Bicarbonates; Cyclic AMP; Cyclic GMP; Dogs; Drug Interactions; Female; Injections, Intra-Arterial; Male; Pancreatic Juice; Phosphodiesterase Inhibitors; Proteins; Secretin; Sincalide; Trifluoperazine

1994
Low level cyclic adenosine 3',5'-monophosphate accumulation analysis of [des-His1, des- Phe6, Glu9] glucagon-NH2 identifies glucagon antagonists from weak partial agonists/antagonists.
    Endocrinology, 1996, Volume: 137, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Amrinone; Animals; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Experimental; Glucagon; Liver; Male; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram

1996
Effects of phosphodiesterase inhibitors on cytokine production by microglia.
    Multiple sclerosis (Houndmills, Basingstoke, England), 1999, Volume: 5, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Anti-Ulcer Agents; Cilostazol; Colforsin; Dipyridamole; DNA Primers; Gene Expression Regulation, Enzymologic; Interleukin-1; Interleukin-6; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Pyrrolidinones; Quinolines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Tetrazoles; Theophylline; Tumor Necrosis Factor-alpha; Vinca Alkaloids; Xanthines

1999
Amrinone reduces ischaemia-reperfusion injury in rat heart.
    European journal of pharmacology, 2000, Aug-25, Volume: 402, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amrinone; Animals; Cardiotonic Agents; Creatine Kinase; L-Lactate Dehydrogenase; Male; Milrinone; Myocardial Reperfusion Injury; Myocardium; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Vasodilation

2000
In contrast to forskolin and 3-isobutyl-1-methylxanthine, amrinone stimulates the cardiac voltage-sensitive release mechanism without increasing calcium-induced calcium release.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Colforsin; Cyclic AMP; Electrophysiology; Enzyme Activators; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Sarcoplasmic Reticulum; Stimulation, Chemical

2001
Design, synthesis and pharmacological evaluation of 6-hydroxy-4-methylquinolin-2(1H)-one derivatives as inotropic agents.
    Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Amrinone; Animals; Atrial Function; Cardiotonic Agents; Catalytic Domain; Cyclic Nucleotide Phosphodiesterases, Type 3; Drug Design; Molecular Sequence Data; Molecular Structure; Phosphodiesterase Inhibitors; Quinolines; Quinolones; Rats; Rats, Wistar; Sequence Alignment

2009