amphotericin-b and puupehenone

amphotericin-b has been researched along with puupehenone* in 1 studies

Other Studies

1 other study(ies) available for amphotericin-b and puupehenone

Article	Year
Puupehanol, a sesquiterpene-dihydroquinone derivative from the marine sponge Hyrtios sp. Bioorganic & medicinal chemistry letters, 2009, Nov-01, Volume: 19, Issue:21 Puupehanol (1), a new sesquiterpene-dihydroquinone derivative, was isolated from the marine sponge Hyrtios sp., along with the known compounds puupehenone (2) and chloropuupehenone (3) that are responsible for the antifungal activity observed in the extract. The structure of 1 was established as (20R,21R)-21-hydroxy-20,21-dihydropuupehenone by extensive spectroscopic and computational methods. Compound 2 exhibited potent activity against Cryptococcus neoformans and Candida krusei with MFCs of 1.25 and 2.50 microg/mL, respectively. Topics: Animals; Antifungal Agents; Benzopyrans; Cyclohexanones; Heterocyclic Compounds, 4 or More Rings; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Conformation; Porifera; Pyrans; Quinones; Sesquiterpenes; Xanthones	2009

Article

Year

Puupehanol, a sesquiterpene-dihydroquinone derivative from the marine sponge Hyrtios sp.

Bioorganic & medicinal chemistry letters, 2009, Nov-01, Volume: 19, Issue:21

Puupehanol (1), a new sesquiterpene-dihydroquinone derivative, was isolated from the marine sponge Hyrtios sp., along with the known compounds puupehenone (2) and chloropuupehenone (3) that are responsible for the antifungal activity observed in the extract. The structure of 1 was established as (20R,21R)-21-hydroxy-20,21-dihydropuupehenone by extensive spectroscopic and computational methods. Compound 2 exhibited potent activity against Cryptococcus neoformans and Candida krusei with MFCs of 1.25 and 2.50 microg/mL, respectively.

Topics: Animals; Antifungal Agents; Benzopyrans; Cyclohexanones; Heterocyclic Compounds, 4 or More Rings; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Conformation; Porifera; Pyrans; Quinones; Sesquiterpenes; Xanthones

2009