amphotericin-b and potassium-hydroxide

We report a case of pulmonary zygomycosis in an adult male diabetic patient who presented with fever and altered sensorium initially and later developed streaky haemoptysis. Bronchoscopy showed picture of necrotizing pneumonia. Sputum was negative for fungal elements on admission but later bronchial wash and repeat sputum samples were positive by microscopy and culture showed growth of Rhizopus species. Immediately the patient was put on amphotericin B but had a bout of massive haemoptysis and succumbed. A high index of suspicion is needed for an early diagnosis and aggressive treatment of this infection in view of the high mortality rate.

Topics: Amphotericin B; Bronchoalveolar Lavage Fluid; Diabetes Complications; Fatal Outcome; Hemoptysis; Humans; Hydroxides; Lung Diseases, Fungal; Male; Middle Aged; Mucormycosis; Pneumonia; Potassium Compounds; Rhizopus; Sputum