amphotericin-b has been researched along with benzyl-isothiocyanate* in 1 studies
1 other study(ies) available for amphotericin-b and benzyl-isothiocyanate
| Article | Year |
|---|---|
Enhancing the fungicidal activity of amphotericin B via vacuole disruption by benzyl isothiocyanate, a cruciferous plant constituent.
Amphotericin B (AmB), a typical polyene macrolide antifungal agent, is widely used to treat systemic mycoses. In the present study, we show that the fungicidal activity of AmB was enhanced by benzyl isothiocyanate (BITC), a cruciferous plant-derived compound, in the budding yeast, Saccharomyces cerevisiae. In addition to forming a molecular complex with ergosterol present in fungal cell membranes to form K Topics: Amphotericin B; Antifungal Agents; Candida albicans; Cell Membrane; Cell Membrane Permeability; Drug Synergism; Drug Therapy, Combination; Ergosterol; Humans; Isothiocyanates; Saccharomyces cerevisiae; Vacuoles | 2021 |