amphotericin-b and acridone

amphotericin-b has been researched along with acridone* in 1 studies

Other Studies

1 other study(ies) available for amphotericin-b and acridone

Article	Year
Antileishmanial and antifungal acridone derivatives from the roots of Thamnosma rhodesica. Phytochemistry, 2004, Volume: 65, Issue:7 Eight furanocoumarins, one coumarin and four acridone derivatives have been identified in the roots of Thamnosma rhodesica (Rutaceae). Rhodesiacridone, one of these acridone derivatives, is reported here for the first time. Its structure was elucidated by spectrometric methods including ESI-HR, EI, DCI mass spectrometry, 1H, 13C and 2D NMR experiments. This novel compound showed activities against the intracellular form of a human pathogen, the protozoan parasite Leishmania major. Two known acridone related compounds, gravacridonediol and 1-hydroxy-10-methylacridone, exhibited activities against the intracellular form of the same parasite and the fungus Cladosporium cucumerinum, respectively. Topics: Acridines; Acridones; Amphotericin B; Animals; Antifungal Agents; Antiprotozoal Agents; Cladosporium; Humans; Leishmania major; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nystatin; Plant Roots; Rutaceae	2004

Article

Year

Antileishmanial and antifungal acridone derivatives from the roots of Thamnosma rhodesica.

Phytochemistry, 2004, Volume: 65, Issue:7

Eight furanocoumarins, one coumarin and four acridone derivatives have been identified in the roots of Thamnosma rhodesica (Rutaceae). Rhodesiacridone, one of these acridone derivatives, is reported here for the first time. Its structure was elucidated by spectrometric methods including ESI-HR, EI, DCI mass spectrometry, 1H, 13C and 2D NMR experiments. This novel compound showed activities against the intracellular form of a human pathogen, the protozoan parasite Leishmania major. Two known acridone related compounds, gravacridonediol and 1-hydroxy-10-methylacridone, exhibited activities against the intracellular form of the same parasite and the fungus Cladosporium cucumerinum, respectively.

Topics: Acridines; Acridones; Amphotericin B; Animals; Antifungal Agents; Antiprotozoal Agents; Cladosporium; Humans; Leishmania major; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nystatin; Plant Roots; Rutaceae

2004