amphetamine and valproic acid

amphetamine has been researched along with valproic acid in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.34)18.7374
1990's2 (6.90)18.2507
2000's18 (62.07)29.6817
2010's6 (20.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Crosset, P; Klawans, HL; Patel, BC1
Bidziński, A; Hauptmann, M; Kostowski, W; Płaźnik, A; Tamborska, E1
Buckland, PR; McGuffin, P; Spurlock, G1
Agmo, A; Alonso, P; Garrido, N; Medrano, A1
Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lasoń, W; Leśkiewicz, M; Tetich, M1
Wozniak, J1
Brody, SA; Geyer, MA; Large, CH; Ong, JC1
Andreazza, AC; Ceresér, KM; Frey, BN; Kapczinski, F; Martins, MR; Quevedo, J; Réus, GZ; Valvassori, SS1
Andreazza, AC; Frey, BN; Hatch, JP; Kapczinski, F; Martins, MR; Quevedo, J; Réus, GZ; Rosa, AR; Valvassori, SS1
Amboni, G; Assis, LC; Corrêa, C; Kapczinski, F; Martins, MR; Quevedo, J; Streck, EL1
Chen, JF; Heidmets, LT; Kalda, A; Shen, HY; Zharkovsky, A1
Andreazza, AC; Cacilhas, AA; Ceresér, KM; Frey, BN; Kapczinski, F; Quevedo, J; Valvassori, SS; Walz, JC1
Kim, JH; Kim, S; Kim, WY1
Amboni, G; Di-Pietro, PB; Kapczinski, F; Luz, G; Quevedo, J; Rezin, GT; Scaini, G; Streck, EL; Valvassori, SS1
Chen, G; Creson, TK; Engel, SR; Hao, Y; Landreth, GE; Maeng, S; Manji, HK; Nekrasova, T; Shen, Y1
Chen, JF; Ferrara, J; Kalda, A; Shen, HY; Yu, L; Zhu, J1
Andreazza, AC; Frey, BN; Giasson, K; Gonçalves, CA; Kapczinski, F; Kauer-Sant'Anna, M; Quevedo, J; Réus, GZ; Ribeiro, L; Salvador, M; Stertz, L; Valvassori, SS; Zanotto, C1
Ferreira, CL; Matté, C; Mattos, C; Quevedo, J; Rezin, GT; Scherer, EB; Streck, EL; Valvassori, SS; Wyse, AT; Zugno, AI1
Adedoyin, A; Beyer, CE; Cai, Z; Comery, TA; Dwyer, JM; Kelly, MP; Liu, Z; Logue, SF; Majchrowski, H; Rosenzweig-Lipson, S1
Agam, G; Almog, O; Belmaker, RH; Bersudsky, Y; Heldman, E; Ishikawa, Y; Mann, L; Vatner, SF1
Douma, TN; Groenink, L; Kolarz, A; Olivier, B; Postma, Y1
Benfante, R; Bolognesi, E; Braida, D; Chiappedi, M; Clerici, M; Corradini, I; De Astis, S; Fornasari, D; Ghezzo, A; Guerini, FR; Matteoli, M; Pattini, L; Ponzoni, L; Sala, M1
Tremblay, M; Winstanley, CA1

Reviews

2 review(s) available for amphetamine and valproic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recognizing and managing bipolar disorder in children.
    The Journal of clinical psychiatry, 2005, Volume: 66 Suppl 1

    Topics: Adolescent; Age Factors; Amphetamine; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Child, Preschool; Comorbidity; Humans; Lithium; Mental Disorders; Treatment Outcome; Valproic Acid

2005

Other Studies

27 other study(ies) available for amphetamine and valproic acid

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Failure of increased brain gamma-aminobutyric acid levels to influence amphetamine-induced stereotyped behavior.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 12, Issue:4

    Topics: Aminobutyrates; Amphetamine; Animals; Behavior; Brain; Brain Chemistry; Drug Interactions; gamma-Aminobutyric Acid; Guinea Pigs; Humans; Male; Stereotyped Behavior; Valproic Acid

1975
Brain neurotransmitter systems mediating behavioral deficits produced by inescapable shock treatment in rats.
    Brain research, 1988, Apr-26, Volume: 447, Issue:1

    Topics: Alanine; Amphetamine; Animals; Antidepressive Agents; Atropine; Brain; Desipramine; Diazepam; Electroshock; Escape Reaction; Male; Motor Activity; Neurotransmitter Agents; Physostigmine; Rats; Rats, Inbred Strains; Valproic Acid

1988
Amphetamine and vigabatrin down regulate aromatic L-amino acid decarboxylase mRNA levels.
    Brain research. Molecular brain research, 1996, Volume: 35, Issue:1-2

    Topics: Amphetamine; Animals; Anticonvulsants; Aromatic-L-Amino-Acid Decarboxylases; Base Sequence; Brain; Enzyme Inhibitors; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Male; Molecular Sequence Data; Oligonucleotide Probes; Organ Specificity; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Transcription, Genetic; Valproic Acid; Vigabatrin

1996
GABAergic drugs inhibit amphetamine-induced distractibility in the rat.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Amphetamine; Animals; Attention; Baclofen; Central Nervous System Stimulants; Enzyme Inhibitors; GABA Agents; GABA Agonists; Male; Motor Activity; Rats; Rats, Wistar; Valproic Acid

1997
Mood stabilizers inhibit glucocorticoid receptor function in LMCAT cells.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Amphetamine; Animals; Anthracenes; Antimanic Agents; Blotting, Western; Carbamazepine; Cell Line; Cell Survival; Chloramphenicol O-Acetyltransferase; Corticosterone; Dose-Response Relationship, Drug; Flavonoids; Gene Expression Regulation, Enzymologic; Imidazoles; Indoles; Inositol; Lithium; Maleimides; Protein Kinase C; Protein Kinase C-alpha; Pyridines; Receptors, Glucocorticoid; Tamoxifen; Tetradecanoylphorbol Acetate; Valproic Acid

2004
An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:3

    Topics: Amphetamine; Anesthetics, Dissociative; Animals; Antimanic Agents; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Ketamine; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenytoin; Reflex, Startle; Valproic Acid

2005
Effects of mood stabilizers on hippocampus BDNF levels in an animal model of mania.
    Life sciences, 2006, Jun-13, Volume: 79, Issue:3

    Topics: Affect; Amphetamine; Animals; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Hippocampus; Lithium; Male; Rats; Rats, Wistar; Valproic Acid

2006
Lithium increases nerve growth factor levels in the rat hippocampus in an animal model of mania.
    Behavioural pharmacology, 2006, Volume: 17, Issue:4

    Topics: Amphetamine; Animals; Antimanic Agents; Bipolar Disorder; Central Nervous System Stimulants; Hippocampus; Lithium; Male; Motor Activity; Nerve Growth Factors; Rats; Rats, Wistar; Valproic Acid

2006
Effects of lithium and valproate on hippocampus citrate synthase activity in an animal model of mania.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, May-09, Volume: 31, Issue:4

    Topics: Amphetamine; Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Citrate (si)-Synthase; Disease Models, Animal; Drug Interactions; Hippocampus; Lithium Chloride; Male; Rats; Rats, Wistar; Valproic Acid

2007
Histone deacetylase inhibitors modulates the induction and expression of amphetamine-induced behavioral sensitization partially through an associated learning of the environment in mice.
    Behavioural brain research, 2007, Jul-19, Volume: 181, Issue:1

    Topics: Amphetamine; Animals; Association Learning; Behavior, Animal; Butyric Acid; Central Nervous System Stimulants; Drug Interactions; Environment; Enzyme Inhibitors; Histones; Male; Mice; Mice, Inbred C57BL; Motor Activity; Time Factors; Valproic Acid

2007
Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania.
    Journal of psychiatric research, 2008, Volume: 42, Issue:5

    Topics: Amphetamine; Animals; Antimanic Agents; Bipolar Disorder; Disease Models, Animal; Hippocampus; Lithium Compounds; Male; Neurotrophin 3; Rats; Rats, Wistar; Sodium Chloride; Valproic Acid

2008
Chronic microinjection of valproic acid into the nucleus accumbens attenuates amphetamine-induced locomotor activity.
    Neuroscience letters, 2008, Feb-13, Volume: 432, Issue:1

    Topics: Amphetamine; Animals; Anticonvulsants; Central Nervous System Stimulants; Disease Models, Animal; Drug Interactions; Hyperkinesis; Male; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Valproic Acid

2008
Brain creatine kinase activity in an animal model of mania.
    Life sciences, 2008, Feb-13, Volume: 82, Issue:7-8

    Topics: Amphetamine; Animals; Antimanic Agents; Bipolar Disorder; Brain; Central Nervous System Stimulants; Creatine Kinase; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Lithium Compounds; Male; Motor Activity; Rats; Rats, Wistar; Valproic Acid

2008
The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement.
    Molecular psychiatry, 2009, Volume: 14, Issue:4

    Topics: Adjuvants, Immunologic; Administration, Oral; Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Central Nervous System Stimulants; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Lithium Chloride; Locomotion; Maze Learning; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Olanzapine; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Swimming; Valproic Acid

2009
Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and DeltaFosB expression in the striatum and locomotor sensitization in mice.
    Neuroscience, 2008, Dec-02, Volume: 157, Issue:3

    Topics: Acetylation; Amphetamine; Animals; Butyric Acid; Central Nervous System Stimulants; Chromatin Immunoprecipitation; Corpus Striatum; CREB-Binding Protein; Drug Interactions; Enzyme Inhibitors; Gene Expression; Histones; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phosphorylation; Proto-Oncogene Proteins c-fos; Time Factors; Valproic Acid

2008
Effects of mood stabilizers on DNA damage in an animal model of mania.
    Journal of psychiatry & neuroscience : JPN, 2008, Volume: 33, Issue:6

    Topics: Amphetamine; Animals; Antimanic Agents; Antioxidants; Bipolar Disorder; Central Nervous System Stimulants; Comet Assay; DNA Damage; Hippocampus; Lipid Peroxidation; Lithium Chloride; Male; Micronucleus Tests; Motor Activity; Oxidative Stress; Rats; Rats, Wistar; Valproic Acid

2008
Na+,K+-ATPase activity in an animal model of mania.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:4

    Topics: Amphetamine; Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Disease Models, Animal; Hippocampus; Lithium Compounds; Male; Motor Activity; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Valproic Acid

2009
The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 92, Issue:4

    Topics: Affect; Amphetamine; Animals; Antimanic Agents; Anxiety; Bipolar Disorder; Chlordiazepoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Male; Mice; Mice, Inbred C57BL; Models, Neurological; Motor Activity; Valproic Acid

2009
Inhibition of specific adenylyl cyclase isoforms by lithium and carbamazepine, but not valproate, may be related to their antidepressant effect.
    Bipolar disorders, 2009, Volume: 11, Issue:8

    Topics: Adenylyl Cyclases; Amphetamine; Analysis of Variance; Animals; Antimanic Agents; Benzazepines; Carbamazepine; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Isoenzymes; Lithium; Mice; Mice, Knockout; Models, Molecular; Motor Activity; Rotarod Performance Test; Swimming; Transfection; Valproic Acid

2009
The amphetamine-chlordiazepoxide mixture, a pharmacological screen for mood stabilizers, does not enhance amphetamine-induced disruption of prepulse inhibition.
    Behavioural brain research, 2011, Nov-20, Volume: 225, Issue:1

    Topics: Acoustic Stimulation; Affect; Amphetamine; Analysis of Variance; Animals; Anticonvulsants; Antimanic Agents; Behavior, Animal; Chlordiazepoxide; Drug Evaluation, Preclinical; Drug Synergism; Hyperkinesis; Inhibition, Psychological; Male; Mice; Mice, Inbred C57BL; Motor Activity; Piperazines; Reflex, Startle; Valproic Acid

2011
Association between SNAP-25 gene polymorphisms and cognition in autism: functional consequences and potential therapeutic strategies.
    Translational psychiatry, 2015, Jan-27, Volume: 5

    Topics: Adolescent; Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Central Nervous System Stimulants; Child; Cognition; Electroencephalography; Enzyme Inhibitors; Female; Heterozygote; Hippocampus; Humans; Male; Mice; Motor Activity; Prefrontal Cortex; Recognition, Psychology; Social Behavior; Synaptosomal-Associated Protein 25; Valproic Acid

2015
Anticonvulsant medications attenuate amphetamine-induced deficits in behavioral inhibition but not decision making under risk on a rat gambling task.
    Behavioural brain research, 2016, 11-01, Volume: 314

    Topics: Amphetamine; Animals; Anticonvulsants; Carbamazepine; Central Nervous System Stimulants; Choice Behavior; Decision Making; Gambling; Male; Rats, Long-Evans; Reinforcement Schedule; Reward; Risk; Valproic Acid

2016