Compounds > amphetamine

amphetamine and tolcapone

amphetamine has been researched along with tolcapone in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Männistö, PT; Törnwall, M1
Männistö, PT; Törnwall, M; Tuomainen, P2

Reviews

1 review(s) available for amphetamine and tolcapone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for amphetamine and tolcapone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Effects of three types of catechol O-methylation inhibitors on L-3,4-dihydroxyphenylalanine-induced circling behaviour in rats.
    European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1

    Topics: Amidines; Amphetamine; Animals; Behavior, Animal; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Clorgyline; Drug Interactions; Drug Synergism; Levodopa; Male; Methylation; Nitriles; Nitrophenols; Pyridones; Rats; Rats, Wistar; Tolcapone

1993
Modulation of rat brain endogenous dopamine metabolism by new inhibitors of catechol O-methyltransferase.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amidines; Amphetamine; Animals; Benzophenones; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Neurons; Nitriles; Nitrophenols; Pimozide; Pyridones; Rats; Rats, Wistar; Tolcapone

1993
Minor effect of tolcapone, a catechol-O-methyltransferase inhibitor, on extracellular dopamine levels modified by amphetamine or pargyline: a microdialysis study in anaesthetized rats.
    Pharmacology & toxicology, 1996, Volume: 78, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Anesthesia, General; Animals; Benzophenones; Catechol O-Methyltransferase Inhibitors; Dopamine; Dopamine Agents; Enzyme Inhibitors; Extracellular Space; Homovanillic Acid; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nitrophenols; Pargyline; Rats; Rats, Wistar; Tolcapone

1996