amphetamine and tetrodotoxin

amphetamine has been researched along with tetrodotoxin in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (33.33)	18.7374
1990's	11 (30.56)	18.2507
2000's	10 (27.78)	29.6817
2010's	3 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chéramy, A; Glowinski, J; Nieoullon, A	1
Basbaum, AI; Brown, JL; Matos, FF; Rollema, H	1
Benuck, M; Jacobson, AE; Reith, ME; Rice, KC; Zimanyi, I	1
Basbaum, AI; Matos, FF; Rollema, H	1
Duffy, P; Kalivas, PW	1
de Vries, JB; Hofsteede, RM; Tuntler, J; Westerink, BH	1
Dluzen, DE; Ramirez, VD	1
Bernardi, G; Calabresi, P; Mercuri, NB	1
Bowyer, JF; Masserano, JM; Weiner, N	1
Brock, JA; Cunnane, TC	1
Dluzen, DE; Laping, NJ; Ramirez, VD	1
Damsma, G; de Vries, JB; Rollema, H; Tuntler, J; Westerink, BH	1
Nelson, SR; Walaszek, EJ	1
Ambache, N; Zar, MA	1
Besson, MJ; Chéramy, A; Gauchy, C; Glowinski, J	1
Casamenti, F; Corradetti, R; Moneti, G; Moroni, F; Pepeu, G	1
Funada, K; Kobayashi, M; Koshikawa, N; Oka, K; Tomiyama, K	1
Abercrombie, ED; Heeringa, MJ	1
Leanza, G; Mandel, RJ; Nilsson, OG; Rosengren, E	1
Desban, M; Gauchy, C; Glowinski, J; Kemel, ML	1
Fibiger, HC; Hamamura, T	1
Kolachana, BS; Saunders, RC; Weinberger, DR	1
Abercrombie, ED; DeBoer, P; Heeringa, MJ	1
Henry, BL; LaHoste, GJ; Marshall, JF	1
Drew, AE; Werling, LL	1
De Vries, JB; Westerink, BH	1
Alfonso, M; do Nascimento, JL; Durán, R; Faro, LR	1
Halim, ND; Lipska, BK; Segal, PN; Weinberger, DR	1
Alfonso, M; Arias, B; Campos, F; Durán, R; Faro, LR; Perez-Vences, D	1
Brussaard, AB; De Rover, M; Lodder, JC; Schoffelmeer, AN	1
Allaman, G; Arneric, SP; Berkenpas, MB; Bertrand, D; Bertrand, S; Groppi, VE; Hajós, M; Higdon, NR; Hoffmann, WE; Hurst, RS; Lawson, JA; Ogier, R; Piotrowski, DW; Raggenbass, M; Rutherford-Root, KL; Wall, TM	1
Gagnaire, F; Micillino, JC	1
Bennett, DJ; Gorassini, MA; Li, X; Rank, MM	1
Borgkvist, A; Feltmann, K; Lindskog, M; Malmlöf, T; Schilström, B	1
Bunner, KD; Cheer, JF; Covey, DP; Garris, PA; Schuweiler, DR	1
Grace, AA; Zimmerman, EC	1

Reviews

1 review(s) available for amphetamine and tetrodotoxin

Article	Year
Pharmacology of the central nervous system. Progress in neurology and psychiatry, 1968, Volume: 23 Topics: Abnormalities, Drug-Induced; Acetylcholine; Adrenocorticotropic Hormone; Amphetamine; Anger; Angiotensin II; Animals; Avoidance Learning; Behavior, Animal; Cats; Central Nervous System; Central Nervous System Diseases; Chick Embryo; Desipramine; Dogs; Guanethidine; Guinea Pigs; Humans; Hypnotics and Sedatives; Imipramine; Memory; Mice; Norepinephrine; Parkinson Disease; Phenacetin; Phenothiazines; Phenoxybenzamine; Rabbits; Rats; Reserpine; Serotonin; Sleep; Sleep, REM; Synapses; Synaptic Transmission; Tetrodotoxin; Theophylline	1968

Article

Year

Pharmacology of the central nervous system.

Progress in neurology and psychiatry, 1968, Volume: 23

Topics: Abnormalities, Drug-Induced; Acetylcholine; Adrenocorticotropic Hormone; Amphetamine; Anger; Angiotensin II; Animals; Avoidance Learning; Behavior, Animal; Cats; Central Nervous System; Central Nervous System Diseases; Chick Embryo; Desipramine; Dogs; Guanethidine; Guinea Pigs; Humans; Hypnotics and Sedatives; Imipramine; Memory; Mice; Norepinephrine; Parkinson Disease; Phenacetin; Phenothiazines; Phenoxybenzamine; Rabbits; Rats; Reserpine; Serotonin; Sleep; Sleep, REM; Synapses; Synaptic Transmission; Tetrodotoxin; Theophylline

1968

Other Studies

35 other study(ies) available for amphetamine and tetrodotoxin

Article	Year
In vivo evidence for a dendritic release of dopamine in the cat substantia nigra. Applied neurophysiology, 1979, Volume: 42, Issue:1-2 Topics: Amphetamine; Animals; Benztropine; Cats; Dendrites; Dextroamphetamine; Dopamine; Potassium; Substantia Nigra; Tetrodotoxin	1979
Do opioids evoke the release of serotonin in the spinal cord? An in vivo microdialysis study of the regulation of extracellular serotonin in the rat. Pain, 1992, Volume: 48, Issue:3 Topics: Amphetamine; Animals; Dialysis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Extracellular Space; Fluoxetine; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Morphine; Narcotics; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Serotonin; Spinal Cord; Tetrodotoxin	1992
Effect of metaphit on dopaminergic neurotransmission in rat striatal slices: involvement of the dopamine transporter and voltage-dependent sodium channel. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Batrachotoxins; Calcium; Carbon Radioisotopes; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Guanidine; Guanidines; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Phencyclidine; Rats; Rats, Inbred Strains; Sodium Channels; Synaptic Transmission; Tetrodotoxin; Tritium; Veratridine	1991
Characterization of monoamine release in the lateral hypothalamus of awake, freely moving rats using in vivo microdialysis. Brain research, 1990, Sep-24, Volume: 528, Issue:1 Topics: Amphetamine; Animals; Biogenic Amines; Dialysis; Hypothalamic Area, Lateral; Imipramine; Male; Motor Activity; Neurotransmitter Agents; Pargyline; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin; Wakefulness	1990
A comparison of axonal and somatodendritic dopamine release using in vivo dialysis. Journal of neurochemistry, 1991, Volume: 56, Issue:3 Topics: Amphetamine; Animals; Axons; Buffers; Dendrites; Dialysis; Dopamine; Male; Mesencephalon; Nucleus Accumbens; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin	1991
Use of calcium antagonism for the characterization of drug-evoked dopamine release from the brain of conscious rats determined by microdialysis. Journal of neurochemistry, 1989, Volume: 52, Issue:3 Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Calcium; Corpus Striatum; Dialysis; Dopamine; Glutamates; Glutamic Acid; Haloperidol; Magnesium; Male; Nomifensine; Ouabain; Piperazines; Potassium; Pyridinium Compounds; Rats; Rats, Inbred Strains; Tetrodotoxin	1989
Progesterone effects upon dopamine release from the corpus striatum of female rats. I. Evidence for interneuronal control. Brain research, 1989, Jan-09, Volume: 476, Issue:2 Topics: Amphetamine; Animals; Corpus Striatum; Dopamine; Female; In Vitro Techniques; Interneurons; Ovariectomy; Progesterone; Rats; Tetrodotoxin	1989
The mechanism of amphetamine-induced inhibition of rat substantia nigra compacta neurones investigated with intracellular recording in vitro. British journal of pharmacology, 1989, Volume: 98, Issue:1 Topics: alpha-Methyltyrosine; Amphetamine; Animals; Cocaine; Dopamine; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potentials; Mesencephalon; Methyltyrosines; Neurons; Potassium Chloride; Rats; Rats, Inbred Strains; Substantia Nigra; Sulpiride; Tetrodotoxin	1989
Inhibitory effects of amphetamine on potassium-stimulated release of [3H]dopamine from striatal slices and synaptosomes. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: Amphetamine; Animals; Calcium; Cobalt; Corpus Striatum; Dopamine; Egtazic Acid; Nifedipine; Potassium; Rats; Synaptosomes; Tetrodotoxin	1987
Studies on the mode of action of bretylium and guanethidine in post-ganglionic sympathetic nerve fibres. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:5 Topics: Amphetamine; Animals; Autonomic Fibers, Postganglionic; Bretylium Compounds; Bretylium Tosylate; Desipramine; Electrophysiology; Guanethidine; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Tetrodotoxin; Vas Deferens	1988
The importance of striatal interneurons in age-related effects upon potassium- and amphetamine-stimulated dopamine release. Brain research, 1988, Apr-05, Volume: 445, Issue:2 Topics: Aging; Amphetamine; Animals; Corpus Striatum; Dopamine; Interneurons; Kinetics; Male; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin	1988
The use of tetrodotoxin for the characterization of drug-enhanced dopamine release in conscious rats studied by brain dialysis. Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:5 Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Haloperidol; Homovanillic Acid; Male; Morphine; Neurotoxins; Nucleus Accumbens; Piperazines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Septal Nuclei; Tetrodotoxin	1987
Evidence against adrenergic motor transmission in the guinea-pig vas deferens. The Journal of physiology, 1971, Volume: 216, Issue:2 Topics: Amphetamine; Animals; Bretylium Compounds; Cold Temperature; Depression, Chemical; Electric Stimulation; Ganglionic Blockers; Guanethidine; Guinea Pigs; Isoproterenol; Male; Motor Neurons; Muscle Contraction; Norepinephrine; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Propranolol; Prostaglandins; Quaternary Ammonium Compounds; Receptors, Adrenergic; Reserpine; Synaptic Transmission; Tetrodotoxin; Tranylcypromine; Tyramine; Vas Deferens	1971
[Liberation of newly synthesized dopamine (DA) at the level of the caudate nucleus in cats]. Journal de physiologie, 1971, Volume: 63, Issue:6 Topics: Amphetamine; Animals; Cats; Caudate Nucleus; Dopamine; Neurosecretion; Potassium; Tetrodotoxin; Tyrosine; Tyrosine 3-Monooxygenase	1971
The release of endogenous GABA and glutamate from the cerebral cortex in the rat. Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 316, Issue:3 Topics: Amino Acids; Amphetamine; Anesthesia; Animals; Cerebral Cortex; Electroencephalography; gamma-Aminobutyric Acid; Glutamates; Male; Neurons; Potassium Chloride; Rats; Tetrodotoxin	1981
In vivo microdialysis evidence for transient dopamine release by benzazepines in rat striatum. Journal of neurochemistry, 1995, Volume: 65, Issue:6 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Benzazepines; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Injections; Male; Microdialysis; Nomifensine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tetrodotoxin	1995
Biochemistry of somatodendritic dopamine release in substantia nigra: an in vivo comparison with striatal dopamine release. Journal of neurochemistry, 1995, Volume: 65, Issue:1 Topics: Amphetamine; Animals; Corpus Striatum; Dendrites; Dopamine; Extracellular Space; Male; Microdialysis; Perfusion; Rats; Rats, Sprague-Dawley; Reserpine; Substantia Nigra; Tetrodotoxin; Time Factors	1995
Amphetamine induces excess release of striatal acetylcholine in vivo that is independent of nigrostriatal dopamine. Brain research, 1994, Aug-08, Volume: 653, Issue:1-2 Topics: Acetylcholine; Amphetamine; Animals; Corpus Striatum; Dopamine; Female; Microdialysis; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Substantia Nigra; Tetrodotoxin	1994
NMDA regulation of dopamine release from proximal and distal dendrites in the cat substantia nigra. Brain research, 1994, Jan-28, Volume: 635, Issue:1-2 Topics: Amphetamine; Animals; Cats; Dendrites; Dopamine; Female; Magnesium; Male; N-Methylaspartate; Nomifensine; Perfusion; Substantia Nigra; Tetrodotoxin	1994
Enhanced stress-induced dopamine release in the prefrontal cortex of amphetamine-sensitized rats. European journal of pharmacology, 1993, Jun-11, Volume: 237, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Electroshock; Homovanillic Acid; Male; Nomifensine; Prefrontal Cortex; Rats; Rats, Wistar; Stress, Psychological; Tetrodotoxin	1993
Augmentation of prefrontal cortical monoaminergic activity inhibits dopamine release in the caudate nucleus: an in vivo neurochemical assessment in the rhesus monkey. Neuroscience, 1995, Volume: 69, Issue:3 Topics: Amphetamine; Animals; Biogenic Monoamines; Caudate Nucleus; Cocaine; Dopamine; Injections; Macaca mulatta; Microdialysis; Potassium Chloride; Prefrontal Cortex; Tetrodotoxin	1995
Biochemistry of somatodendritic dopamine release in substantia nigra: an in vivo comparison with striatal dopamine release. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: Amphetamine; Animals; Corpus Striatum; Dendrites; Dopamine; Haloperidol; Nerve Endings; Quinpirole; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine; Substantia Nigra; Tetrodotoxin	1998
Dopamine D1 receptors synergize with D2, but not D3 or D4, receptors in the striatum without the involvement of action potentials. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Sep-01, Volume: 20, Issue:17 Topics: Action Potentials; Amphetamine; Animals; Corpus Striatum; Dopamine Antagonists; Genes, fos; Indans; Indoles; Male; Piperidines; Proto-Oncogene Proteins c-fos; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Dopamine D4; Tetrodotoxin	2000
Protein kinase C regulation of dopamine transporter initiated by nicotinic receptor activation in slices of rat prefrontal cortex. Journal of neurochemistry, 2001, Volume: 77, Issue:3 Topics: Alkaloids; Amphetamine; Animals; Benzophenanthridines; Calcium; Calcium Channel Blockers; Carrier Proteins; Dopamine; Dopamine Plasma Membrane Transport Proteins; Egtazic Acid; Enzyme Inhibitors; Indoles; Male; Maleimides; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nicotine; omega-Conotoxin GVIA; Phenanthridines; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Second Messenger Systems; Sodium Channels; Staurosporine; Tetrodotoxin; Tritium; Veratridine	2001
A method to evaluate the diffusion rate of drugs from a microdialysis probe through brain tissue. Journal of neuroscience methods, 2001, Aug-15, Volume: 109, Issue:1 Topics: Amphetamine; Animals; Brain; Diffusion; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Microdialysis; Microelectrodes; Nomifensine; Pharmaceutical Preparations; Potassium Chloride; Rats; Rats, Wistar; Sulpiride; Tetrodotoxin	2001
Mechanism of action of methylmercury on in vivo striatal dopamine release. Possible involvement of dopamine transporter. Neurochemistry international, 2002, Volume: 40, Issue:5 Topics: Amphetamine; Animals; Calcium; Corpus Striatum; Culture Media; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Isotonic Solutions; Membrane Glycoproteins; Membrane Transport Proteins; Methylmercury Compounds; Nerve Tissue Proteins; Nomifensine; Potassium; Rats; Rats, Sprague-Dawley; Reserpine; Ringer's Solution; Tetrodotoxin	2002
Effects of reversible inactivation of the neonatal ventral hippocampus on behavior in the adult rat. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-01, Volume: 22, Issue:7 Topics: Age Factors; Aging; Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Central Nervous System Stimulants; Cohort Studies; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Interpersonal Relations; Male; Microinjections; Motor Activity; Psychomotor Agitation; Rats; Rats, Sprague-Dawley; Schizophrenia; Tetrodotoxin	2002
Mechanisms underlying domoic acid-induced dopamine release from striatum: an in vivo microdialysis study. Neurochemical research, 2003, Volume: 28, Issue:10 Topics: Amphetamine; Animals; Calcium; Corpus Striatum; Culture Media; Dopamine; Dopamine Uptake Inhibitors; Kainic Acid; Male; Marine Toxins; Microdialysis; Neurotoxins; Nomifensine; Potassium; Rats; Rats, Sprague-Dawley; Reserpine; Sodium Channel Blockers; Tetrodotoxin	2003
Intermittent morphine treatment induces a long-lasting increase in cholinergic modulation of GABAergic synapses in nucleus accumbens of adult rats. Synapse (New York, N.Y.), 2005, Volume: 55, Issue:1 Topics: Acetylcholine; Amphetamine; Anesthetics, Local; Animals; Central Nervous System Stimulants; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mecamylamine; Membrane Potentials; Morphine; Narcotics; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Synapses; Tetrodotoxin	2005
A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Apr-27, Volume: 25, Issue:17 Topics: Acetylcholine; Acoustic Stimulation; Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Amphetamine; Animals; Animals, Newborn; Calcium; Cell Line; Central Nervous System Stimulants; Cholinergic Agonists; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Epithelial Cells; Evoked Potentials, Auditory; Hippocampus; Humans; In Vitro Techniques; Isoxazoles; Male; Membrane Potentials; Microinjections; Neurons; Nicotine; Oocytes; Patch-Clamp Techniques; Phenylurea Compounds; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tetrodotoxin; Time Factors; Xenopus	2005
Effects of triadimefon on extracellular dopamine, DOPAC, HVA and 5-HIAA in adult rat striatum. Toxicology, 2006, Jan-16, Volume: 217, Issue:2-3 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Chromatography, High Pressure Liquid; Dialysis Solutions; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Fluid; Fungicides, Industrial; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Microdialysis; Neostriatum; Piperazines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Stereotyped Behavior; Tetrodotoxin; Time Factors; Triazoles	2006
Role of endogenous release of norepinephrine in muscle spasms after chronic spinal cord injury. Journal of neurophysiology, 2007, Volume: 97, Issue:5 Topics: Adrenergic Uptake Inhibitors; Amphetamine; Anesthetics, Local; Animals; Anterior Horn Cells; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Female; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Norepinephrine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Skin; Spasm; Spinal Cord Injuries; Tetrodotoxin	2007
Dopamine in the hippocampus is cleared by the norepinephrine transporter. The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:4 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug Interactions; Hippocampus; Idazoxan; Male; Microdialysis; Morpholines; Nomifensine; Norepinephrine Plasma Membrane Transport Proteins; Raclopride; Rats; Rats, Wistar; Reboxetine; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Wakefulness	2012
Amphetamine elevates nucleus accumbens dopamine via an action potential-dependent mechanism that is modulated by endocannabinoids. The European journal of neuroscience, 2016, Volume: 43, Issue:12 Topics: Action Potentials; Amphetamine; Animals; Cannabinoid Receptor Antagonists; Dopamine; Dopamine Agents; Endocannabinoids; Male; Neurons; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Sodium Channel Blockers; Tetrodotoxin; Ventral Tegmental Area	2016
The Nucleus Reuniens of the Midline Thalamus Gates Prefrontal-Hippocampal Modulation of Ventral Tegmental Area Dopamine Neuron Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 08-24, Volume: 36, Issue:34 Topics: Action Potentials; Amphetamine; Anesthetics, Inhalation; Anesthetics, Local; Animals; Central Nervous System Stimulants; Dopaminergic Neurons; Excitatory Amino Acid Agonists; Hippocampus; Hyperkinesis; Isoflurane; Male; Midline Thalamic Nuclei; N-Methylaspartate; Neural Pathways; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Ventral Tegmental Area	2016