amphetamine and selegiline

amphetamine has been researched along with selegiline in 88 studies

Research

Studies (88)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (17.05)	18.7374
1990's	46 (52.27)	18.2507
2000's	20 (22.73)	29.6817
2010's	6 (6.82)	24.3611
2020's	1 (1.14)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Reynolds, GP; Riederer, P; Sandler, M	1
Blau, K; Elsworth, JD; Lees, AJ; Reynolds, GP; Sandler, M; Stern, GM	1
Knoll, B; Knoll, J; Tímár, J	1
Kuczenski, R; Okuda, C; Segal, DS	1
Kraemer, T; Maurer, HH	1
Baker, GB; Caffaro, LE; Coutts, RT; Greenshaw, AJ; Paetsch, PR; Rauw, GA	1
Nag, M; Nandi, N	1
Männistö, PT; Törnwall, M	1
Dluzen, DE; McDermott, JL	1
Knoll, B; Knoll, J; Timár, J; Yasar, S	3
Salonen, JS	1
Arbuthnott, GW; Butcher, SP; Fairbrother, IS; Kelly, JS	1
Nickel, B; Schulze, G; Szelenyi, I	2
Antonin, KH; Bieck, PR; Hoffmann, E; Jedrychowski, M; Nilsson, E; Schick, C; Schulz, R	1
Kuroiwa, Y; Yamada, Y; Yamamoto, T; Yoshida, T	1
Bretton, C; Hof, P; Ofori, S; Schorderet, M	1
Salach, JI; Weyler, W	1
Robinson, JB	1
Philips, SR	1
Dallo, J; Knoll, J; Yen, TT	1
Hardie, R; Lees, AJ; Sandler, M; Stern, GM	1
Hardie, RJ; Lees, AJ; Sandler, M; Stern, GM	1
Jalfre, M; Pawelec, C; Porsolt, RD; Roux, S	1
Coutts, RT; Foster, BC; Pasutto, FM	1
Knoll, J; Zsilla, G	1
Elsworth, JD; Lees, AJ; Sandler, M; Stern, GM; Ward, C	1
Czurkó, A; Faludi, B; Karádi, Z; Knoll, J; Lénárd, L; Niedetzky, C; Vida, I	1
Kikura, R; Nakahara, Y	1
La Croix, R; Pianezzola, E; Strolin Benedetti, M	1
Mahmood, I; Mason, WD; Neau, SH	1
Bergman, J; Yasar, S	1
Bhattacharya, N; Holland, D; Murray, B; Oh, C; Tatton, WG	1
Gelowitz, DL; Lai, CT; Richardson, JS; Wishart, TB; Yu, PH	1
Gyarmati, Z; Härsing, GL; Knoll, J; Tekes, K; Timár, J	1
Dadgar, D; Mamer, OA; Reimer, ML; Siddiqui, AW; Zavitsanos, AP	1
Greedan, A; Needleman, SB; Romberg, RW; Snyder, JJ	1
Boulton, AA; Davis, BA; Fang, J; Lai, CT; Li, XM; Paterson, IA; Yu, PH; Zhang, X; Zuo, DM	1
Gaál, J; Lengyel, J; Magyar, K; Szatmári, I; Szebeni, G; Székács, G	1
Bosc, M; Deffond, D; Dordain, G; Dostert, P; Fiorentini, F; La Croix, R; Persiani, S; Strolin Benedetti, M; Vernay, D	1
Lakshmana, MK; Munirathinam, S; Raju, TR	1
Barna, L; Gyarmati, Z; Knoll, B; Timár, J	1
Barrett, JS; De Witt, KE; Ireland, J; Morales, RJ; Rajewski, G; Rohatagi, S; Szego, P	1
Cooper, T; Gaál, J; Hashim, A; Lajtha, A; Sershen, H	1
Goldberg, JP; Goldberg, SR; Yasar, S	1
Kikuta, C; Ludwig, G; Mascher, HJ; Millendorfer, A; Schiel, H	1
Bernardi, G; Bonci, A; Mercuri, NB; Scarponi, M; Siniscalchi, A	1
Behar, D; Schaller, JL	1
Barrett, JS; DeWitt, KE; Morales, RJ; Rohatagi, S	1
Barrett, JS; DeWitt, KE; Lessard, D; Morales, RJ; Rohatagi, S	1
Báthori, M; Fürst, S; Hollósi, I; Kalász, H; Szebeni, G; Tarjányi, Z	1
Wu, WR; Zhu, XZ	1
Chaturvedi, AK; Kupiec, TC	1
Bartók, T; Fürst, S; Haberle, D; Hennings, EC; Kalász, H; Kiss, JP; Magyar, K; Szöko, E	1
Finberg, JP; Lamensdorf, I; Porat, S; Simantov, R	1
Fukushima, S; Hasegawa, M; Kimura, K; Maseda, C; Matsubara, K; Uezono, T	1
Caslavska, J; Ramseier, A; Thormann, W	1
Kalász, H; Magyar, K; Szökö, E	1
Gentsch, C; Spooren, WP; Waldmeier, P	1
Bach, MV; Baker, GB; Coutts, RT	1
Finberg, JP; Ilani, T; Lamensdorf, I	1
Banchelli, G; Galeotti, N; Ghelardini, C; Pirisino, R; Raimondi, L	1
Ahlner, J; Andersson, MC; Kronstrand, R; Larson, G	1
Cody, JT	1
Kamata, T; Katagi, M; Miki, A; Nakajima, K; Nishikawa, M; Nishioka, H; Tatsuno, M; Tsuchihashi, H; Tsutsumi, H	1
Foltz, RL; Moody, DE; Slawson, MH; Taccogno, JL	1
Knoll, B; Knoll, J; Miklya, I	1
Ahlner, J; Dizdar, N; Kronstrand, R; Larson, G	1
Magyar, K; Szöko, E; Tábi, T	1
Brewer, F; Clarke, A; Corn, TH; Hartig, F; Johnson, ES; Mallard, N; Taylor, S	1
Borbás, T; Dalmadi, B; Magyar, K; Szöko, E; Tábi, T; Tihanyi, K	1
Mohanakumar, KP; Saravanan, KS; Senthilkumar, KS; Sindhu, KM	1
Kinney, GG; Ransom, RW; Shughrue, PJ; Vanko, AE; West, BD	1
Ikeda, N; Inoue, N; Itoh, S; Kudo, K; Nishida, K	1
Lengyel, J; Magyar, K; Szatmáry, I; Szebeni, G	1
Aoki, Y; Endo, S; Fujino, Y; Fujita, Y; Inoue, Y; Niitsu, H; Onodera, M; Takahashi, K; Takei, M	1
Everhart, T; Harris, DS; Jacob, P; Jones, RT; Lin, E; Mendelson, JE	1
Dimpfel, W; Hoffmann, JA; Müller, T; Oehlwein, C	1
Magyar, K; Szökő, E; Tábi, T; Vécsei, L	1
Bu, J; Qiao, Z; Shen, M; Wu, HJ; Xiang, P; Zhuo, XY	1
Chen, L; Duan, G; Shen, B; Shi, Y; Wang, S; Xiang, P; Yan, H; Yu, Y	1
Choi, H; Kang, S; Kim, J; Park, Y; Shin, I; Yang, W	1

Reviews

4 review(s) available for amphetamine and selegiline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Neurochemical, neuroprotective and neurorescue effects of aliphatic N-methylpropargylamines; new MAO-B inhibitors without amphetamine-like properties. Progress in brain research, 1995, Volume: 106 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Cell Count; Cerebral Cortex; Hippocampus; Mice; Monoamine Oxidase Inhibitors; Rats; Selegiline	1995
Are metabolites of l-deprenyl (selegiline) useful or harmful? Indications from preclinical research. Journal of neural transmission. Supplementum, 1996, Volume: 48 Topics: Amphetamine; Animals; Biotransformation; Cocaine; Cognition; Conditioning, Operant; Drug Evaluation, Preclinical; Electroencephalography; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Nootropic Agents; Phenethylamines; Rats; Rats, Inbred F344; Reinforcement, Psychology; Saimiri; Selegiline; Self Administration	1996
Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results. Journal of occupational and environmental medicine, 2002, Volume: 44, Issue:5 Topics: Amphetamine; Amphetamines; Benzphetamine; Caffeine; Furans; Humans; Methamphetamine; Molecular Structure; Prenylamine; Prodrugs; Pyrazoles; Pyrazolones; Selegiline; Substance Abuse Detection; Sydnones; Theophylline	2002

Trials

8 trial(s) available for amphetamine and selegiline

Article	Year
Deprenyl is metabolized to methamphetamine and amphetamine in man. British journal of clinical pharmacology, 1978, Volume: 6, Issue:6 Topics: Amphetamine; Biotransformation; Humans; Male; Methamphetamine; Phenethylamines; Selegiline	1978
Clinical and pharmacological aspects of (-)-deprenyl treatment in Parkinson's disease. Modern problems of pharmacopsychiatry, 1983, Volume: 19 Topics: Amphetamine; Clinical Trials as Topic; Double-Blind Method; Humans; Hydrogen-Ion Concentration; Parkinson Disease; Phenethylamines; Selegiline	1983
Lack of pharmacokinetic interaction between the selective dopamine agonist cabergoline and the MAO-B inhibitor selegiline. Journal of neural transmission. Supplementum, 1995, Volume: 45 Topics: Aged; Amphetamine; Amphetamines; Antiparkinson Agents; Cabergoline; Dopamine Agonists; Drug Interactions; Ergolines; Female; Humans; Male; Methamphetamine; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease; Selegiline	1995
Integrated pharmacokinetic and metabolic modeling of selegiline and metabolites after transdermal administration. Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:7 Topics: Administration, Cutaneous; Amphetamine; Amphetamines; Antiparkinson Agents; Area Under Curve; Humans; Male; Methamphetamine; Models, Biological; Monoamine Oxidase Inhibitors; Pilot Projects; Regression Analysis; Selegiline	1997
Pharmacokinetic evaluation of a selegiline pulsatile oral delivery system. Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:8 Topics: Administration, Oral; Adult; Amphetamine; Amphetamines; Area Under Curve; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Delivery Systems; Humans; Intestinal Absorption; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Pilot Projects; Reference Values; Selegiline; Therapeutic Equivalency; Time Factors	1997
Quantitative analysis of desmethylselegiline, methamphetamine, and amphetamine in hair and plasma from Parkinson patients on long-term selegiline medication. Journal of analytical toxicology, 2003, Volume: 27, Issue:3 Topics: Aged; Aged, 80 and over; Amphetamine; Amphetamines; Antiparkinson Agents; Drug Administration Schedule; Female; Hair; Hair Color; Humans; Male; Melanins; Methamphetamine; Middle Aged; Parkinson Disease; Patient Compliance; Selegiline; Spectrophotometry	2003
A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition. Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:11 Topics: Administration, Oral; Adult; Aged; Amphetamine; Biological Availability; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Female; Humans; Hydroxyindoleacetic Acid; Male; Metabolic Clearance Rate; Methamphetamine; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenethylamines; Selegiline	2003
A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion. BMC clinical pharmacology, 2009, Aug-01, Volume: 9 Topics: Administration, Cutaneous; Adult; Affect; Amphetamine; Amphetamines; Analysis of Variance; Cocaine; Dopamine Uptake Inhibitors; Drug Interactions; Female; Homovanillic Acid; Humans; Infusions, Intravenous; Male; Methamphetamine; Methoxyhydroxyphenylglycol; Monitoring, Physiologic; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenethylamines; Prolactin; Selegiline; Statistics, Nonparametric; Substance Withdrawal Syndrome; Young Adult	2009

Other Studies

76 other study(ies) available for amphetamine and selegiline

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
2-Phenylethylamine and amphetamine in human brain: effects of L-deprenyl in Parkinson's disease [proceedings]. Biochemical Society transactions, 1979, Volume: 7, Issue:1 Topics: Amphetamine; Brain; Humans; Parkinson Disease; Phenethylamines; Selegiline; Tissue Distribution	1979
(-)Deprenyl (selegiline) is devoid of amphetamine-like behavioural effects in rats. Acta physiologica Hungarica, 1992, Volume: 79, Issue:2 Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Escape Reaction; Female; Male; Motor Activity; Rats; Rats, Wistar; Selegiline; Stereotyped Behavior	1992
Deprenyl alters behavior and caudate dopamine through an amphetamine-like action. Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Caudate Nucleus; Clorgyline; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Selegiline	1992
Toxicological detection of selegiline and its metabolites in urine using fluorescence polarization immunoassay (FPIA) and gas chromatography-mass spectrometry (GC-MS) and differentiation by enantioselective GC-MS of the intake of selegiline from abuse of Archives of toxicology, 1992, Volume: 66, Issue:9 Topics: Amphetamine; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; Selegiline; Stereoisomerism; Substance Abuse Detection	1992
Electron-capture gas chromatographic procedure for simultaneous determination of amphetamine and N-methylamphetamine. Journal of chromatography, 1992, Jan-17, Volume: 573, Issue:2 Topics: Amphetamine; Animals; Chromatography, Gas; Electrons; Gas Chromatography-Mass Spectrometry; Liver; Male; Methamphetamine; Rats; Rats, Inbred Strains; Selegiline	1992
Antidepressants and brain respiration. Bioscience reports, 1991, Volume: 11, Issue:1 Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Chlorides; Chlorpromazine; Clorgyline; Glucose; Imipramine; Lithium; Lithium Chloride; Male; Oxygen Consumption; Rats; Selegiline; Tranylcypromine	1991
Acute toxicity of three new selective COMT inhibitors in mice with special emphasis on interactions with drugs increasing catecholaminergic neurotransmission. Pharmacology & toxicology, 1991, Volume: 69, Issue:1 Topics: Amphetamine; Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Clorgyline; Convulsants; Desipramine; Drug Interactions; Lethal Dose 50; Levodopa; Male; Mice; Motor Activity; Nitriles; Nomifensine; Pentanones; Selegiline; Synaptic Transmission; Yohimbine	1991
The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats. Journal of neural transmission. General section, 1991, Volume: 85, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amphetamine; Animals; Corpus Striatum; Dopamine; In Vitro Techniques; Levodopa; Male; Rats; Selegiline	1991
A (-) deprenyl-derived new spectrum psychostimulant. Acta physiologica Hungarica, 1990, Volume: 75 Suppl Topics: Amphetamine; Animals; Brain Chemistry; Cefoxitin; Central Nervous System Stimulants; Dopamine; In Vitro Techniques; Motor Activity; Muscle, Smooth, Vascular; Phenethylamines; Rabbits; Rats; Selegiline; Synaptic Transmission	1990
Determination of the amine metabolites of selegiline in biological fluids by capillary gas chromatography. Journal of chromatography, 1990, Apr-27, Volume: 527, Issue:1 Topics: Amphetamine; Animals; Chromatography, Gas; Dogs; Methamphetamine; Phenethylamines; Selegiline	1990
Comparison of the effects of (-)deprenyl, 1-phenyl-2-propyl-aminopentane (MK-306) and amphetamine on the striatal and limbic dopaminergic system. Acta physiologica Hungarica, 1990, Volume: 75 Suppl Topics: Amphetamine; Animals; Cefoxitin; Corpus Striatum; Dopamine; Limbic System; Phenethylamines; Rats; Receptors, Dopamine; Selegiline	1990
Comparison of the dependence capacity of amphetamine, MK-306 and (-)deprenyl. Acta physiologica Hungarica, 1990, Volume: 75 Suppl Topics: Amphetamine; Animals; Cefoxitin; Learning; Phenethylamines; Rats; Selegiline; Substance-Related Disorders	1990
Effects of selective monoamine oxidase inhibitors on the in vivo release and metabolism of dopamine in the rat striatum. Journal of neurochemistry, 1990, Volume: 55, Issue:3 Topics: Amphetamine; Animals; Catecholamines; Clorgyline; Corpus Striatum; Dopamine; Monoamine Oxidase Inhibitors; Nomifensine; Pargyline; Potassium; Rats; Rats, Inbred Strains; Selegiline; Serotonin; Veratrine	1990
Effect of enantiomers of deprenyl (selegiline) and amphetamine on physical abuse liability and cortical electrical activity in rats. Neuropharmacology, 1990, Volume: 29, Issue:11 Topics: Amphetamine; Animals; Body Weight; Cerebral Cortex; Codeine; Electric Conductivity; Electroencephalography; Evoked Potentials; Female; Isomerism; Rats; Rats, Inbred Strains; Reference Values; Selegiline; Substance Withdrawal Syndrome	1990
Tyramine kinetics and pressor sensitivity during monoamine oxidase inhibition by selegiline. Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:5 Topics: Administration, Oral; Adult; Amphetamine; Blood Pressure; Chromatography, Gas; Double-Blind Method; Electrocardiography; Female; Humans; Injections, Intravenous; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Phenethylamines; Phenylacetates; Random Allocation; Selegiline; Tyramine	1989
Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: relationship of metabolism to MAO-B inhibitory potency. Xenobiotica; the fate of foreign compounds in biological systems, 1986, Volume: 16, Issue:2 Topics: Amphetamine; Animals; Chromatography, Gas; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxylation; In Vitro Techniques; Male; Methamphetamine; Methimazole; Methylcholanthrene; Microsomes, Liver; Monoamine Oxidase Inhibitors; Phenethylamines; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Selegiline	1986
Investigation of dopamine content, synthesis, and release in the rabbit retina in vitro: I. Effects of dopamine precursors, reserpine, amphetamine, and L-DOPA decarboxylase and monoamine oxidase inhibitors. Journal of neurochemistry, 1986, Volume: 47, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Dopamine; Female; Levodopa; Male; Monoamine Oxidase Inhibitors; Pargyline; Rabbits; Reserpine; Retina; Selegiline; Tyrosine	1986
Purification and properties of mitochondrial monoamine oxidase type A from human placenta. The Journal of biological chemistry, 1985, Oct-25, Volume: 260, Issue:24 Topics: 2,2'-Dipyridyl; Amphetamine; Animals; Cattle; Chromatography; Clorgyline; Disulfides; Electrophoresis, Polyacrylamide Gel; Female; Flavins; Humans; Kinetics; Mitochondria; Molecular Weight; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidation-Reduction; Placenta; Pregnancy; Selegiline; Solubility; Sulfhydryl Compounds	1985
Stereoselectivity and isoenzyme selectivity of monoamine oxidase inhibitors. Enantiomers of amphetamine, N-methylamphetamine and deprenyl. Biochemical pharmacology, 1985, Dec-01, Volume: 34, Issue:23 Topics: Amphetamine; Animals; Isoenzymes; Kinetics; Liver; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Phenethylamines; Rats; Rats, Inbred Strains; Selegiline; Stereoisomerism	1985
Amphetamine, p-hydroxyamphetamine and beta-phenethylamine in mouse brain and urine after (-)- and (+)-deprenyl administration. The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:11 Topics: Amphetamine; Amphetamines; Animals; Biogenic Amines; Brain; Male; Mice; p-Hydroxyamphetamine; Phenethylamines; Selegiline; Stereoisomerism	1981
Long-lasting, true aphrodisiac effect of (-)-deprenyl in sexually sluggish old male rats. Modern problems of pharmacopsychiatry, 1983, Volume: 19 Topics: Aging; Amphetamine; Animals; Aphrodisiacs; Castration; Clorgyline; Copulation; Male; Phenethylamines; Rats; Selegiline; Sexual Behavior, Animal; Time Factors	1983
Clinical and pharmacological problems of deprenyl (selegiline) treatment in Parkinson's disease. Acta neurologica Scandinavica. Supplementum, 1983, Volume: 95 Topics: Amphetamine; Humans; Hydrogen-Ion Concentration; Methamphetamine; Parkinson Disease; Phenethylamines; Selegiline	1983
Discrimination of the amphetamine cue. Effects of A, B and mixed type inhibitors of monoamine oxidase. Neuropharmacology, 1984, Volume: 23, Issue:5 Topics: Amphetamine; Animals; Cues; Cyclopropanes; Discrimination Learning; Discrimination, Psychological; Male; Monoamine Oxidase Inhibitors; Rats; Selegiline	1984
Fungal metabolism of (-)-deprenyl and pargyline. Life sciences, 1981, Nov-09, Volume: 29, Issue:19 Topics: Amphetamine; Benzylamines; Biotransformation; Mucorales; Pargyline; Phenethylamines; Selegiline	1981
The action of (-) deprenyl on monoamine turnover rate in rat brain. Advances in biochemical psychopharmacology, 1982, Volume: 31 Topics: Amphetamine; Animals; Brain; Brain Stem; Catecholamines; Corpus Striatum; Dopamine; Female; Male; Norepinephrine; Phenethylamines; Rats; Receptors, Dopamine; Selegiline	1982
The contribution of amphetamine metabolites of (-)-deprenyl to its antiparkinsonian properties. Journal of neural transmission, 1982, Volume: 54, Issue:1-2 Topics: Amphetamine; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrogen-Ion Concentration; Levodopa; Methamphetamine; Middle Aged; Parkinson Disease; Phenethylamines; Selegiline	1982
Responses of forebrain neurons to the MAO-B blocker L-deprenyl. Brain research bulletin, 1995, Volume: 36, Issue:3 Topics: Acetylcholine; Amphetamine; Animals; Clorgyline; Electrophoresis; Female; gamma-Aminobutyric Acid; Macaca mulatta; Male; Microelectrodes; Monoamine Oxidase; Neurons; Prosencephalon; Rats; Rats, Inbred Strains; Selegiline; Species Specificity	1995
Hair analysis for drugs of abuse. IX. Comparison of deprenyl use and methamphetamine use by hair analysis. Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:2 Topics: Administration, Oral; Adult; Amphetamine; Animals; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Male; Methamphetamine; Middle Aged; Rats; Selegiline; Stereoisomerism	1995
Sensitive high-performance liquid chromatographic method for the determination of the three main metabolites of selegiline (L-deprenyl) in human plasma. Journal of chromatography. B, Biomedical applications, 1994, Jun-03, Volume: 656, Issue:1 Topics: Amphetamine; Biotransformation; Chromatography, High Pressure Liquid; Fluorenes; Humans; Indicators and Reagents; Methamphetamine; Quality Control; Selegiline	1994
An enzymatic assay for the MAO-B inhibitor selegiline in plasma. Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:7 Topics: Amphetamine; Amphetamines; Animals; Brain; Humans; Hydroxyquinolines; Male; Methamphetamine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selegiline; Spectrometry, Fluorescence	1994
Evaluation of physical dependence liability of l-deprenyl (selegiline) in animals. Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:6 Pt 2 Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electroencephalography; Female; Male; Rats; Rats, Sprague-Dawley; Selegiline; Stereoisomerism; Substance-Related Disorders; Time Factors	1994
Amphetamine-like effect of l-deprenyl (selegiline) in drug discrimination studies. Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:6 Pt 2 Topics: Amphetamine; Amphetamines; Animals; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Rats; Saimiri; Selegiline	1994
(-)-Deprenyl alters the survival of adult murine facial motoneurons after axotomy: increases in vulnerable C57BL strain but decreases in motor neuron degeneration mutants. Journal of neuroscience research, 1994, May-01, Volume: 38, Issue:1 Topics: Amphetamine; Animals; Axons; Cell Survival; Facial Nerve; Methamphetamine; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Neurologic Mutants; Motor Neurons; Nerve Degeneration; Selegiline; Species Specificity	1994
Chronic L-deprenyl or L-amphetamine: equal cognitive enhancement, unequal MAO inhibition. Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:1 Topics: Amphetamine; Animals; Cognition; Learning; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Selegiline; Space Perception; Stimulation, Chemical	1994
Further proof that (-)deprenyl fails to facilitate mesolimbic dopaminergic activity. Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:3 Topics: Amphetamine; Animals; Cell-Free System; Corpus Striatum; Dopamine; Female; Limbic System; Male; Motor Activity; Olfactory Bulb; Phenethylamines; Rats; Rats, Wistar; Selegiline; Stereotyped Behavior	1993
Determination of amphetamine, methamphetamine and desmethyldeprenyl in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry. Biological mass spectrometry, 1993, Volume: 22, Issue:4 Topics: Amphetamine; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; Quality Control; Regression Analysis; Selegiline	1993
Methamphetamine and amphetamine derived from the metabolism of selegiline. Journal of forensic sciences, 1995, Volume: 40, Issue:6 Topics: Amphetamine; Gas Chromatography-Mass Spectrometry; Humans; Male; Methamphetamine; Selegiline	1995
Gas chromatographic procedure for simultaneous determination of selegiline metabolites, amphetamine, methamphetamine and demethyl-deprenyl in pig plasma. Acta physiologica Hungarica, 1995, Volume: 83, Issue:2 Topics: Amphetamine; Amphetamines; Animals; Capsules; Central Nervous System Stimulants; Chromatography, Gas; Female; Indicators and Reagents; Methamphetamine; Monoamine Oxidase Inhibitors; Selegiline; Swine; Tablets	1995
(-) deprenyl attenuates aluminium induced neurotoxicity in primary cortical cultures. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration, 1996, Volume: 5, Issue:2 Topics: Aluminum Chloride; Aluminum Compounds; Amphetamine; Animals; Animals, Newborn; Biomarkers; Cell Survival; Cells, Cultured; Cerebral Cortex; Chlorides; L-Lactate Dehydrogenase; Neurons; Neurotoxins; Pargyline; Rats; Rats, Wistar; Selegiline	1996
Differences in some behavioural effects of deprenyl and amphetamine enantiomers in rats. Physiology & behavior, 1996, Volume: 60, Issue:2 Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Female; Head Movements; Male; Monoamine Oxidase Inhibitors; Motor Activity; Rats; Rats, Wistar; Selegiline; Stereoisomerism; Stereotyped Behavior	1996
Absorption and presystemic metabolism of selegiline hydrochloride at different regions in the gastrointestinal tract in healthy males. Pharmaceutical research, 1996, Volume: 13, Issue:10 Topics: Administration, Oral; Adult; Amphetamine; Amphetamines; Biological Availability; Cross-Over Studies; Duodenum; Gastric Mucosa; Humans; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Selegiline	1996
Metabolism of (-)-deprenyl and PF-(-)-deprenyl in brain after central and peripheral administration. Neurochemical research, 1996, Volume: 21, Issue:10 Topics: Amphetamine; Animals; Brain; Corpus Striatum; Gas Chromatography-Mass Spectrometry; Injections, Subcutaneous; Male; Methamphetamine; Microdialysis; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selegiline; Sensitivity and Specificity	1996
Pharmacokinetics and bioequivalence of the main metabolites of selegiline: desmethylselegiline, methamphetamine and amphetamine after oral administration of selegiline. International journal of clinical pharmacology and therapeutics, 1997, Volume: 35, Issue:1 Topics: Administration, Oral; Adult; Amphetamine; Amphetamines; Biological Availability; Central Nervous System Stimulants; Half-Life; Humans; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Selegiline; Therapeutic Equivalency	1997
Monoamine oxidase inhibition causes a long-term prolongation of the dopamine-induced responses in rat midbrain dopaminergic cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Apr-01, Volume: 17, Issue:7 Topics: Amphetamine; Animals; Clorgyline; Cocaine; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Isoenzymes; Membrane Potentials; Mesencephalon; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Nomifensine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Selegiline; Sulpiride	1997
Selegiline for the delivery of small doses of amphetamine. The Journal of neuropsychiatry and clinical neurosciences, 1997,Spring, Volume: 9, Issue:2 Topics: Adolescent; Adult; Amphetamine; Attention Deficit Disorder with Hyperactivity; Child; Child Development Disorders, Pervasive; Humans; Intellectual Disability; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Selegiline	1997
Gas-chromatographic study on the stereoselectivity of deprenyl metabolism. Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:4-5 Topics: Amphetamine; Gas Chromatography-Mass Spectrometry; Humans; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Selegiline; Stereoisomerism	1998
The amphetamine-like reinforcing effect and mechanism of L-deprenyl on conditioned place preference in mice. European journal of pharmacology, 1999, Jan-01, Volume: 364, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Conditioning, Operant; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Reinforcement, Psychology; Selegiline	1999
Stereochemical determination of selegiline metabolites in postmortem biological specimens. Journal of forensic sciences, 1999, Volume: 44, Issue:1 Topics: Accidents, Aviation; Aged; Amphetamine; Antiparkinson Agents; Autopsy; Gas Chromatography-Mass Spectrometry; Humans; Male; Methamphetamine; Selegiline; Stereoisomerism	1999
Analysis of deprenyl metabolites in the rat brain using HPLC-ES-MS. Current medicinal chemistry, 1999, Volume: 6, Issue:4 Topics: Amphetamine; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Isomerism; Male; Mass Spectrometry; Methamphetamine; Microdialysis; Rats; Rats, Wistar; Selegiline	1999
Effect of low-dose treatment with selegiline on dopamine transporter (DAT) expression and amphetamine-induced dopamine release in vivo. British journal of pharmacology, 1999, Volume: 126, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Carrier Proteins; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Selegiline	1999
Stereoselective analyses of selegiline metabolites: possible urinary markers for selegiline therapy. Forensic science international, 1999, Apr-26, Volume: 101, Issue:2 Topics: Adult; Amphetamine; Amphetamines; Biomarkers; Chromatography, Gas; Diagnosis, Differential; Female; Humans; Male; Methamphetamine; Middle Aged; Monoamine Oxidase Inhibitors; Selegiline; Stereoisomerism; Substance Abuse Detection; Substance-Related Disorders	1999
Stereoselective screening for and confirmation of urinary enantiomers of amphetamine, methamphetamine, designer drugs, methadone and selected metabolites by capillary electrophoresis. Electrophoresis, 1999, Volume: 20, Issue:13 Topics: Amphetamine; Antiparkinson Agents; Designer Drugs; Electrophoresis, Capillary; Fluorescence Polarization Immunoassay; Humans; Methadone; Methamphetamine; Reproducibility of Results; Selegiline; Spectrophotometry, Ultraviolet; Stereoisomerism	1999
Metabolic transformation of deprenyl enantiomers in rats. Neurobiology (Budapest, Hungary), 1999, Volume: 7, Issue:2 Topics: Amphetamine; Animals; Dealkylation; Kidney; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Selegiline; Stereoisomerism	1999
The effect of a subchronic post-lesion treatment with (-)-deprenyl on the sensitivity of 6-OHDA-lesioned rats to apomorphine and d-amphetamine. Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:9-10 Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Sprague-Dawley; Selegiline	1999
Metabolism of N,N-dialkylated amphetamines, including deprenyl, by CYP2D6 expressed in a human cell line. Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:3 Topics: Amphetamine; Amphetamines; Benzphetamine; Cell Line; Chromatography, Gas; Cytochrome P-450 CYP2D6; Humans; Methamphetamine; Methylation; Microsomes; Models, Chemical; Selegiline; Transfection	2000
Selective monoamine oxidase subtype inhibition and striatal extracellular dopamine in the guinea-pig. British journal of pharmacology, 2000, Volume: 130, Issue:8 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Catecholamines; Clorgyline; Corpus Striatum; Dialysis Solutions; Dihydroxyphenylalanine; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Guinea Pigs; Homovanillic Acid; Isoenzymes; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperazines; Potassium Chloride; Rats; Selegiline; Synaptosomes; Tritium; Tyrosine 3-Monooxygenase	2000
Selective inhibition of amine oxidases differently potentiate the hypophagic effect of benzylamine in mice. European journal of pharmacology, 2001, Feb-09, Volume: 413, Issue:1 Topics: Allyl Compounds; Amphetamine; Animals; Benzylamines; Clorgyline; Dopamine Agents; Drug Synergism; Feeding Behavior; Male; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; Piperazines; Propylamines; Pyridines; Selegiline; Serotonin Antagonists; Substrate Specificity; Tetraethylammonium	2001
Incorporation of selegiline metabolites into hair after oral selegiline intake. Journal of analytical toxicology, 2001, Volume: 25, Issue:7 Topics: Administration, Oral; Adult; Amphetamine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; False Positive Reactions; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Melanins; Methamphetamine; Monoamine Oxidase Inhibitors; Selegiline; Sensitivity and Specificity; Substance Abuse Detection	2001
Urinary excretion of selegiline N-oxide, a new indicator for selegiline administration in man. Xenobiotica; the fate of foreign compounds in biological systems, 2002, Volume: 32, Issue:9 Topics: Adrenergic Uptake Inhibitors; Adult; Amphetamine; Amphetamines; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Methamphetamine; Models, Chemical; Monoamine Oxidase Inhibitors; Selegiline; Spectrometry, Mass, Electrospray Ionization; Time Factors	2002
Quantitative analysis of selegiline and three metabolites (N-desmethylselegiline, methamphetamine, and amphetamine) in human plasma by high-performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry. Journal of analytical toxicology, 2002, Volume: 26, Issue:7 Topics: Amphetamine; Amphetamines; Chromatography, High Pressure Liquid; Freezing; Humans; Mass Spectrometry; Methamphetamine; Monoamine Oxidase Inhibitors; Reproducibility of Results; Selegiline	2002
An HPLC tracing of the enhancer regulation in selected discrete brain areas of food-deprived rats. Life sciences, 2003, May-09, Volume: 72, Issue:25 Topics: Amphetamine; Animals; Benzofurans; Brain Chemistry; Catecholamines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Drive; Feeding Behavior; Food Deprivation; Hunger; Male; Monoamine Oxidase Inhibitors; Motor Activity; Neurons; Neurotransmitter Agents; Orientation; Propylamines; Rats; Rats, Wistar; Selegiline; Serotonin	2003
Chiral characterization of deprenyl-N-oxide and other deprenyl metabolites by capillary electrophoresis using a dual cyclodextrin system in rat urine. Electrophoresis, 2003, Volume: 24, Issue:15 Topics: Amphetamine; Animals; Biotransformation; Cyclodextrins; Electrophoresis, Capillary; Ephedrine; Male; Monoamine Oxidase Inhibitors; Phenylpropanolamine; Rats; Rats, Wistar; Reproducibility of Results; Selegiline; Sensitivity and Specificity; Stereoisomerism	2003
Assessment of the N-oxidation of deprenyl, methamphetamine, and amphetamine enantiomers by chiral capillary electrophoresis: an in vitro metabolism study. Electrophoresis, 2004, Volume: 25, Issue:16 Topics: 2-Hydroxypropyl-beta-cyclodextrin; Amphetamine; beta-Cyclodextrins; Buffers; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Methamphetamine; Microsomes, Liver; Molecular Structure; Oxidation-Reduction; Oxygenases; Recombinant Proteins; Selegiline; Stereoisomerism	2004
L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats. Neurochemistry international, 2006, Volume: 49, Issue:1 Topics: Amphetamine; Animals; Catalase; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Electron Transport Complex I; Hydroxyl Radical; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Selegiline; Substantia Nigra; Superoxide Dismutase; Tyrosine 3-Monooxygenase; Uncoupling Agents; Up-Regulation	2006
Amphetamine-induced locomotor activity is reduced in mice following MPTP treatment but not following selegiline/MPTP treatment. Pharmacology, biochemistry, and behavior, 2006, Volume: 84, Issue:1 Topics: Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Locomotion; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Selegiline	2006
High-performance liquid chromatographic-mass spectrometric determination of methamphetamine and amphetamine enantiomers, desmethylselegiline and selegiline, in hair samples of long-term methamphetamine abusers or selegiline users. Journal of analytical toxicology, 2006, Volume: 30, Issue:4 Topics: Amphetamine; Amphetamines; Antiparkinson Agents; Chromatography, High Pressure Liquid; Hair; Humans; Methamphetamine; Parkinson Disease; Selegiline; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection	2006
Pharmacokinetic studies of (-)-deprenyl and some of its metabolites in mouse. Journal of neural transmission. Supplementum, 2007, Issue:72 Topics: Administration, Oral; Amphetamine; Amphetamines; Animals; Antiparkinson Agents; Biological Availability; Biotransformation; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Male; Metabolic Clearance Rate; Methamphetamine; Mice; Mice, Inbred Strains; Monoamine Oxidase Inhibitors; Selegiline	2007
Detection of levorotatory methamphetamine and levorotatory amphetamine in urine after ingestion of an overdose of selegiline. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2008, Volume: 128, Issue:10 Topics: Adult; Amphetamine; Biomarkers; Drug Overdose; Gas Chromatography-Mass Spectrometry; Humans; Male; Methamphetamine; Parkinson Disease; Selegiline; Suicide, Attempted	2008
Switch from selegiline to rasagiline is beneficial in patients with Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996), 2013, Volume: 120, Issue:5 Topics: Aged; Amphetamine; Antiparkinson Agents; Drug Substitution; Female; Humans; Indans; Male; Methamphetamine; Middle Aged; Motor Activity; Neuroprotective Agents; Parkinson Disease; Selegiline; Severity of Illness Index; Time Factors	2013
The pharmacokinetic evaluation of selegiline ODT for the treatment of Parkinson's disease. Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:5 Topics: Administration, Oral; Amphetamine; Biological Availability; Drug Evaluation; Humans; Levodopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Randomized Controlled Trials as Topic; Selegiline; Tablets	2013
[Identification of Methamphetamine Abuse and Selegiline Use： Chiral Analysis of Methamphetamine and Amphetamine in Urine]. Fa yi xue za zhi, 2017, Volume: 33, Issue:6 Topics: Amphetamine; Amphetamine-Related Disorders; Central Nervous System Stimulants; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; Selegiline; Substance Abuse Detection; Tandem Mass Spectrometry	2017
Pharmacokinetics of selegiline, R-methamphetamine, R-amphetamine, and desmethylselegiline in oral fluid after a single oral administration of selegiline. Drug testing and analysis, 2019, Volume: 11, Issue:6 Topics: Administration, Oral; Amphetamine; Amphetamines; Humans; Liquid-Liquid Extraction; Methamphetamine; Monoamine Oxidase Inhibitors; Saliva; Selegiline; Substance Abuse Detection	2019
Detection of l-Methamphetamine and l-Amphetamine as Selegiline Metabolites. Journal of analytical toxicology, 2021, Feb-06, Volume: 45, Issue:1 Topics: Amphetamine; Central Nervous System Stimulants; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; Republic of Korea; Selegiline; Substance Abuse Detection	2021