amphetamine has been researched along with phencyclidine in 140 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (23.57) | 18.7374 |
| 1990's | 33 (23.57) | 18.2507 |
| 2000's | 49 (35.00) | 29.6817 |
| 2010's | 24 (17.14) | 24.3611 |
| 2020's | 1 (0.71) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Esposito, RU; Kornetsky, C | 1 |
| Feldon, J; Weiner, I | 1 |
| Kimball, KA; Wenger, GR | 1 |
| Benuck, M; Jacobson, AE; Reith, ME; Rice, KC; Zimanyi, I | 1 |
| Abreu, M; Ferkany, J; French, ED; Levenson, S | 1 |
| Kornblum, RN; Reddy, SK | 1 |
| Iversen, SD; Rupniak, NM; Samson, NA; Steventon, MJ | 1 |
| Cannon-Spoor, HE; Freed, WJ | 1 |
| Ahlenius, S; Ericson, E | 1 |
| Dimpfel, W; Spüler, M | 1 |
| Rayport, S; Sulzer, D | 1 |
| Michael, RP; Schaefer, GJ | 1 |
| Borne, RF; Davis, WM; Ketema, H; Walker, LA | 1 |
| Ash, KO; Pearson, SD; Urry, FM | 1 |
| Johnson, KM; Snell, LD | 1 |
| French, ED | 1 |
| Chiang, CN; Lee, CC | 1 |
| Contreras, PC; Freedman, R; Hoffer, B; Jacobson, AE; Johnson, S; Lessor, RA; O'Donohue, TL; Olsen, K; Rafferty, MF; Rice, KC | 1 |
| Wise, RA | 1 |
| Freedman, R; Hoffer, BJ; Johnson, SW | 1 |
| Balster, RL | 1 |
| Berger, P; Jacobson, AE; Reith, ME; Rice, KC; Sershen, H | 1 |
| Bagchi, SP | 1 |
| Marcus, RJ; Mori, K; Spooner, CE; Wallach, MB; Winters, WD | 1 |
| Levine, JM; Miller, RE; Mirsky, IA | 1 |
| Leonard, BE | 1 |
| Henriksson, BG; Järbe, TU | 1 |
| Sperling, A | 1 |
| Consroe, PF | 2 |
| Brown, JK; Griffin, GD; Shapazian, L | 1 |
| Bartolini, A; Domino, EF | 1 |
| Schneider, C | 1 |
| Morton, EC; Vaupel, DB | 1 |
| Crump, S; Freed, WJ; Jeste, DV | 1 |
| Forney, RB; Haggerty, GC; Richter, JA | 1 |
| Frank, RS | 1 |
| Bowyer, JF; Spuhler, KP; Weiner, N | 1 |
| Johnson, KM; Leventer, SM | 1 |
| Ellison, G; Nelson, L; Potthoff, AD | 1 |
| Robertson, HA | 1 |
| Adams, PM; Castellani, S | 1 |
| Johnson, KM; Vickroy, TW | 1 |
| DiSclafani, A; Gardner, ER; Hall, RC | 1 |
| Ary, TE; Komiskey, HL | 1 |
| Bervoets, K; Maurel-Remy, S; Millan, MJ | 1 |
| Goldberg, SR; Katz, JL; Schindler, CW | 1 |
| Papanikolaou, A; Salamone, JD; Sokolowski, JD; Steinpreis, RE | 1 |
| Cockerham, H; Gibb, RP; Goldfogel, GA; Lawson, GM; Raisys, VA | 1 |
| Alexander, RC; Freed, W; Wright, R | 1 |
| Giorgi, SN; Meeker, JE | 1 |
| Fontana, D; Mele, A; Pert, A | 1 |
| Hashim, A; Javitt, DC; Lajtha, A; Sershen, H | 1 |
| Hashimoto, Y; Moriya, F | 1 |
| Joksimović, J; Tomić, M; Vukosavić, S | 1 |
| Haapalinna, A; Kobilka, BK; Sallinen, J; Scheinin, M; Viitamaa, T | 1 |
| Cabeza de Vaca, S; Carr, KD | 1 |
| Dubrovsky, T; ElSohly, MA; Salamone, SJ; Towt, J; Tsai, SC; Twarowska, B | 1 |
| Bruce, KH; English, JA; Paul, IA | 1 |
| Kinney, GG; Saywell, KL; Tricklebank, MD; Wilkinson, LO | 1 |
| Roche, JK; Turgeon, SM | 1 |
| Bada, HS; Bauer, CR; ElSohly, MA; Lester, BM; Murphy, TP; Shankaran, S; Smeriglio, VL; Stanford, DF; Verter, J; Walls, HC; Wright, LL | 1 |
| Audinot, V; Bervoets, K; Brocco, M; Gobert, A; Joly, F; Maurel, S; Millan, MJ; Newman-Tancredi, A; Rivet, J | 1 |
| Barber, DJ; Cooper, AJ; Griffiths, MR; Mitchell, IJ | 1 |
| Danysz, W; Karcz-Kubicha, M; Wedzony, K; Zajaczkowski, W | 1 |
| Levine, B; Moore, KA; Smith, ML; Werner, C; Zannelli, RM | 1 |
| Joksimović, J; Tomić, M | 1 |
| Case, LC; Turgeon, SM | 1 |
| Dai, J; Guan, HJ; Zhu, XZ | 1 |
| Kanazir, S; Rakic, L; Ruzdijic, S; Veskov, R; Vukosavic, S | 1 |
| Balla, A; Javitt, DC; Koneru, R; Sershen, H; Smiley, J | 1 |
| Drai, D; Elmer, G; Golani, I; Kafkafi, N; Mayo, C | 1 |
| Azampanah, A; Fletcher, PJ; Sills, TL | 1 |
| Adams, BW; Bradberry, CW; Moghaddam, B | 1 |
| Ito, C | 1 |
| Moghaddam, B; Stefani, MR | 1 |
| Evenden, J | 1 |
| Nishikawa, T | 1 |
| Balla, A; Javitt, DC; Koneru, R; Serra, M; Sershen, H | 1 |
| Kanazir, S; Milanović, D; Milosević, J; Rakić, L; Ruzdijić, S | 1 |
| Fulford, A; Lapiz, MD; Marsden, CA; Mason, R; Muchimapura, S; Parker, T | 1 |
| Herman, ZS; Obuchowicz, E | 1 |
| Grottick, AJ; Higgins, GA; Le Pen, G; Moreau, JL | 1 |
| Copolov, DL; Kusljic, S; van den Buuse, M | 1 |
| Gray, JA; Joseph, MH; McDonald, LM; Moran, PM; Stephenson, JD; Vythelingum, GN | 1 |
| Balla, A; Burch, S; Javitt, DC; Sershen, H; Suckow, R; Xie, S | 1 |
| Janać, B; Milanović, D; Pesić, V; Rakić, L; Tomić, M; Veskov, R | 1 |
| Gerber, DJ; Tonegawa, S | 1 |
| Castner, SA; Goldman-Rakic, PS; Williams, GV | 1 |
| Compton, AD; Wiley, JL | 1 |
| Hugel, J; Kalasinsky, KS; Kish, SJ | 1 |
| Kusljic, S; van den Buuse, M | 1 |
| Fletcher, PJ; Kapur, S; Tenn, CC | 1 |
| Jacobsen, JP; Mørk, A; Rodriguiz, RM; Wetsel, WC | 1 |
| Fletcher, PJ; Kapur, S; Lovic, V; Rizos, Z; Tenn, CC | 1 |
| Kanazir, S; Milanovic, D; Pesic, V; Rakic, L; Ruzdijic, S | 1 |
| Chapin, DS; Fujiwara, RA; James, LC; McCarthy, SA; McNeish, JD; Menniti, FS; Schmidt, CJ; Siuciak, JA; Stock, JL; Strick, CA; Williams, RD | 1 |
| Griffey, KI; Johnson, BG; Knitowski, KM; McKinzie, DL; Monn, JA; Perry, KW; Rorick-Kehn, LM; Salhoff, CR; Schoepp, DD; Tizzano, JP; Witkin, JM | 1 |
| Harris, AJ; Honey, A; Jones, DN; Jones, GA; Kelly, FM; Kew, JN; Maycox, PR; Melarange, RA; Murdock, PR; Robbins, MJ; Rocheville, M; Rourke, C; Rupniak, T; Soffin, EM; Starr, KR; Strum, J | 1 |
| Geyer, MA; Hedlund, PB; Markou, A; Semenova, S; Sutcliffe, JG | 1 |
| Aspromonte, JM; Balla, A; Cooper, TB; Javitt, DC; Sershen, H; Xie, S | 1 |
| Chapin, DS; Harms, JF; Martin, AN; McCarthy, SA; Schmidt, CJ; Siuciak, JA | 1 |
| Caldwell, HK; Stephens, SL; Young, WS | 1 |
| Cochran, SM; Egerton, A; McGregor, S; Morris, BJ; Pratt, JA; Reid, L | 1 |
| Martin, S; van den Buuse, M | 1 |
| Baker, GB; Barlow, KB; George, SR; Kapur, S; Mamo, D; Natesan, S; Nobrega, JN; Odontiadis, J; Reckless, GE | 1 |
| Barlow, KB; Kapur, S; Natesan, S; Nobrega, JN; Reckless, GE | 1 |
| Hori, E; Maior, R; Maior, RS; Mao, CV; Nishijo, H; Ono, T | 1 |
| Bafile, E; Compagnone, D; Curini, R; D'Ascenzo, G; Romolo, FS; Sergi, M | 1 |
| Hu, G; Li, M; Sun, T | 1 |
| Feldon, J; Singer, P; Yee, BK | 2 |
| Benke, D; Boison, D; Feldon, J; Grampp, T; Itohara, S; Iwasato, T; Möhler, H; Prenosil, G; Singer, P; Yee, BK | 1 |
| Advani, T; Cassano, T; Giuffrida, A; Hensler, JG; Seillier, A | 1 |
| Banasikowski, TJ; Beninger, RJ; Beuk, J; Boivin, GA; Reynolds, JN; van Adel, M | 1 |
| Basu, AC; Benneyworth, MA; Coyle, JT | 1 |
| Baylor, MR; Bynum, ND; Lewallen, CM; Mitchell, JM; Ropero-Miller, JD; Stout, PR | 1 |
| Li, M; Mead, A; Sun, T | 1 |
| Bruun, AT; Bundgaard, C; de Jong, IE; Didriksen, M; Elster, L; Frederiksen, K; Larsen, PH; Redrobe, JP; Smith, GP | 1 |
| Alberati, D; Borroni, E; Hainzl, D; Hauser, N; Knoflach, F; Lengyel, J; Moreau, JL; Mory, R; Pinard, E; Schlotterbeck, G; Wettstein, JG | 1 |
| Hammond, B; Hussain, I; Kew, JN; Stean, TO; Upton, N; Virley, DJ; Waters, KA | 1 |
| Gross, G; Mezler, M; Mueller, BK; Relo, AL; van Gaalen, MM | 1 |
| Bortolotto, Z; Ceolin, L; Collingridge, G; Hanna, L; Johnson, B; Lodge, D; Lucas, S; Monn, J | 1 |
| Moriya, F | 1 |
| Gogos, A; Thwaites, SJ; van den Buuse, M | 1 |
| Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A | 1 |
| Aerts, N; Fellini, L; Steckler, T; Talpos, JC | 1 |
| Biguet, NF; Ingallinesi, M; Le Bouil, L; Mallet, J; Mannoury la Cour, C; Meloni, R; Millan, MJ; Ravassard, P; Thi, AD | 1 |
| Freeto, SM; LeQue, JJ; Ohouo, PY; Rosano, TG; Wood, M | 1 |
| Gogos, A; Kusljic, S; Thwaites, SJ; van den Buuse, M | 1 |
| Coen, KM; Fletcher, PJ; Lê, AD; Li, Z | 1 |
| Bhat, L; Cantillon, M; Huang, M; Kwon, S; Meltzer, HY; Michael, E; Rajagopal, L | 1 |
| Borrelli, E; Caron, MG; Pack, TF; Payne, K; Peterson, SM; Rose, SJ | 1 |
| Hales, CA; Houghton, CJ; Robinson, ESJ | 1 |
| Christensen, KV; Christoffersen, CT; Clausen, D; Didriksen, M; Egebjerg, J; Fejgin, K; Kallunki, P; Larsen, PH; Lauridsen, JB; Mørk, A; Nielsen, J; Nielsen, V; Sotty, F; Werge, TM; Yavich, L | 1 |
| Hewes, N; Lodge, D; McCarthy, AP; Robinson, ESJ; Shanks, E; Wafford, KA; Wood, CM | 1 |
| de Jong, LAA; Duijst, WLJM; Olyslager, EJH | 1 |
| Gogos, A; Kusljic, S; van den Buuse, M | 1 |
6 review(s) available for amphetamine and phencyclidine
| Article | Year |
|---|---|
Psychomotor stimulant properties of addictive drugs.
Topics: Amphetamine; Animals; Caffeine; Electric Stimulation; Medial Forebrain Bundle; Motor Activity; Narcotics; Nicotine; Phencyclidine; Substance-Related Disorders | 1988 |
Analysis of hallucinogenic drugs.
Topics: Amphetamine; Cannabis; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Dronabinol; Fluorometry; Hallucinogens; Indoles; Lysergic Acid Diethylamide; Mescaline; Methods; Phencyclidine; Psilocybin; Specimen Handling; Spectrophotometry; Tryptamines | 1972 |
Specific pharmacological management of acute toxicity due to "psychedelic" drugs.
Topics: Acute Disease; Alkaloids; Amines; Amphetamine; Antidotes; Atropa belladonna; Cannabis; Ergolines; Hallucinogens; Humans; Indoles; Lysergic Acid Diethylamide; Parasympatholytics; Phencyclidine; Phenethylamines; Plants, Medicinal; Plants, Toxic; Psilocybin; Toxicology | 1972 |
Analysis of overall gene expression induced by amphetamine and phencyclidine: novel targets for the treatment of drug psychosis and schizophrenia.
Topics: Amphetamine; Animals; Dopamine Agents; Gene Expression Regulation; Hallucinogens; Humans; Phencyclidine; Psychoses, Substance-Induced; Schizophrenia | 2002 |
[Genetic study on schizophrenia and its recurrence utilizing pharmacological models].
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Agents; Humans; Ketamine; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Recurrence; Schizophrenia | 2002 |
Animal models of working memory: insights for targeting cognitive dysfunction in schizophrenia.
Topics: Amphetamine; Animals; Cognition Disorders; Dopamine; Glutamic Acid; Humans; Memory, Short-Term; Models, Animal; Phencyclidine; Prefrontal Cortex; Schizophrenia | 2004 |
1 trial(s) available for amphetamine and phencyclidine
| Article | Year |
|---|---|
Oxytocin as a natural antipsychotic: a study using oxytocin knockout mice.
Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Apomorphine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Oxytocin; Phencyclidine; Psychoacoustics; Reflex, Startle; Sensory Gating; Sex Factors | 2009 |
133 other study(ies) available for amphetamine and phencyclidine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Euphorigenic drugs: effects on the reward pathways of the brain.
Topics: Amphetamine; Animals; Brain; Cocaine; Electroencephalography; Euphoria; Morphine; Narcotic Antagonists; Narcotics; Neural Pathways; Pentazocine; Phencyclidine; Rats; Reward; Self Stimulation | 1979 |
Phencyclidine does not disrupt latent inhibition in rats: implications for animal models of schizophrenia.
Topics: Amphetamine; Animals; Behavior, Animal; Conditioning, Operant; Conditioning, Psychological; Disease Models, Animal; Male; Phencyclidine; Rats; Rats, Inbred Strains; Schizophrenic Psychology | 1992 |
Titrating matching-to-sample performance: effects of drugs of abuse and intertrial interval.
Topics: Amphetamine; Animals; Cocaine; Columbidae; Male; Pentobarbital; Phencyclidine; Reaction Time; Reinforcement Schedule; Substance-Related Disorders | 1992 |
Effect of metaphit on dopaminergic neurotransmission in rat striatal slices: involvement of the dopamine transporter and voltage-dependent sodium channel.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Batrachotoxins; Calcium; Carbon Radioisotopes; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Guanidine; Guanidines; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Phencyclidine; Rats; Rats, Inbred Strains; Sodium Channels; Synaptic Transmission; Tetrodotoxin; Tritium; Veratridine | 1991 |
Effects of competitive N-methyl-D-aspartate antagonists on midbrain dopamine neurons: an electrophysiological and behavioral comparison to phencyclidine.
Topics: Amino Acids; Amphetamine; Animals; Behavior, Animal; Dopamine; Electrophysiology; Limbic System; Male; Mesencephalon; Motor Activity; N-Methylaspartate; Neurons; Nucleus Accumbens; Oxidopamine; Phencyclidine; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Effects of the Taser in fatalities involving police confrontation.
Topics: Adult; Amphetamine; Cause of Death; Cocaine; Firearms; Humans; Immobilization; Male; Phencyclidine; Substance-Related Disorders; Wounds, Gunshot | 1991 |
Induction of cognitive impairment by scopolamine and noncholinergic agents in rhesus monkeys.
Topics: Amphetamine; Animals; Behavior, Animal; Cognition; Dronabinol; Lorazepam; Macaca mulatta; Male; Morphine; Phencyclidine; Scopolamine; Spatial Behavior; Yohimbine | 1991 |
A possible role of AA2 excitatory amino acid receptors in the expression of stimulant drug effects.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Amphetamine; Animals; Apomorphine; Behavior, Animal; Central Nervous System Stimulants; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glutamates; Mice; Motor Activity; Phencyclidine; Quinoxalines; Receptors, Amino Acid; Receptors, Cell Surface; Stereotyped Behavior | 1990 |
Phencyclidine-induced disruption of an aversely motivated two-choice successive discrimination in the rat.
Topics: Amphetamine; Animals; Antipsychotic Agents; Avoidance Learning; Benzamides; Discrimination Learning; Discrimination, Psychological; Drug Interactions; Haloperidol; Male; Phencyclidine; Rats; Rats, Inbred Strains; Remoxipride | 1990 |
Dizocilpine (MK-801), ketamine and phencyclidine: low doses affect brain field potentials in the freely moving rat in the same way as activation of dopaminergic transmission.
Topics: Amphetamine; Animals; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Ketamine; Levodopa; Male; Membrane Potentials; Mice; Phencyclidine; Rats; Rats, Inbred F344; Synaptic Transmission; Time Factors | 1990 |
Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action.
Topics: Amphetamine; Animals; Cells, Cultured; Chromaffin Granules; Cocaine; Dopamine; Fenfluramine; Hydrogen-Ion Concentration; Imipramine; Immunoenzyme Techniques; Mesencephalon; Microscopy, Electron; Neurons; Phencyclidine; Psychotropic Drugs; Rats; Serotonin; Tyramine | 1990 |
Interactions of naloxone with morphine, amphetamine and phencyclidine on fixed interval responding for intracranial self-stimulation in rats.
Topics: Amphetamine; Animals; Brain; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Naloxone; Phencyclidine; Rats; Rats, Inbred Strains; Reinforcement Schedule; Self Stimulation | 1990 |
Pharmacologic and toxicologic effects of di(beta-phenylisopropyl)amine (DPIA) in rats and mice.
Topics: Amphetamine; Animals; Antidotes; Blood Pressure; Eating; Heart Rate; Hemodynamics; Lethal Dose 50; Male; Mice; Motor Activity; Phencyclidine; Rats; Rats, Inbred Strains; Stereoisomerism; Stereotyped Behavior; Tremor | 1990 |
Mechanism of false-negative urine cannabinoid immunoassay screens by Visine eyedrops.
Topics: Amphetamine; Benzalkonium Compounds; Cannabinoids; Cocaine; Dronabinol; False Negative Reactions; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; Immunoassay; Morphine; Nasal Decongestants; Oxazepam; Phencyclidine; Secobarbital; Ultrafiltration | 1989 |
Antagonism of N-methyl-D-aspartate-induced transmitter release in the rat striatum by phencyclidine-like drugs and its relationship to turning behavior.
Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aspartic Acid; Benzomorphans; Chlorpromazine; Clozapine; Corpus Striatum; Cyclazocine; Dioxolanes; Dopamine; Haloperidol; Ketamine; Male; Mathematics; Motor Activity; N-Methylaspartate; Phencyclidine; Posture; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
Effects of N-allylnormetazocine (SKF 10,047), phencyclidine, and other psychomotor stimulants in the rat following 6-hydroxydopamine lesion of the ventral tegmental area.
Topics: Amphetamine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Scopolamine; Tegmentum Mesencephali | 1986 |
Maternal-fetal transfer of abused substances: pharmacokinetic and pharmacodynamic data.
Topics: Amphetamine; Animals; Cocaine; Dronabinol; Female; Fetus; Humans; Kinetics; Lysergic Acid Diethylamide; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine; Nicotine; Phencyclidine; Pregnancy; Substance-Related Disorders | 1985 |
Metaphit, an acylating ligand for phencyclidine receptors: characterization of in vivo actions in the rat.
Topics: Acylation; Amphetamine; Animals; Ataxia; Caudate Nucleus; Dose-Response Relationship, Drug; Injections, Intraventricular; Ligands; Male; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Stereotyped Behavior | 1986 |
Investigation of the failure of parenterally administered haloperidol to antagonize dopamine released from micropipettes in the caudate.
Topics: Amphetamine; Animals; Apomorphine; Caudate Nucleus; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Hydroxydopamines; Infusions, Parenteral; Male; Oxidopamine; Phencyclidine; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Clinical implications of behavioral pharmacology research on phencyclidine.
Topics: Amphetamine; Animals; Barbiturates; Drug Tolerance; Humans; Macaca mulatta; Phencyclidine; Phencyclidine Abuse; Self Administration; Substance-Related Disorders | 1986 |
Metaphit prevents locomotor activation induced by various psychostimulants and interferes with the dopaminergic system in mice.
Topics: Amphetamine; Animals; Biogenic Amines; Brain Chemistry; Cocaine; Dopamine; Male; Mice; Mice, Inbred BALB C; Motor Activity; Phencyclidine; Receptors, Dopamine | 1988 |
Cocaine and phencyclidine. Heterogenous dopaminergic interactions with tetrabenazine.
Topics: Amphetamine; Animals; Cocaine; Dopamine; Drug Interactions; In Vitro Techniques; Mitochondria; Nalidixic Acid; Naphthyridines; Phencyclidine; Phenylalanine; Rats; Receptors, Dopamine; Reserpine; Synaptosomes; Tetrabenazine; Tyrosine | 1985 |
Reticular multiple unit activity during a progression of states induced by CNS excitants. 3.
Topics: Amphetamine; Animals; Behavior, Animal; Cats; Cerebral Cortex; Dextroamphetamine; Electroencephalography; Female; Hydroxybutyrates; Lysergic Acid Diethylamide; Male; Mescaline; Mesencephalon; Neurons; Pentylenetetrazole; Phencyclidine; Reticular Formation | 1969 |
Effects of psychoactive drugs on nonverbal communication and group social behavior of monkeys.
Topics: Aggression; Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Conditioning, Operant; Cooperative Behavior; Electroshock; Facial Expression; Haplorhini; Humans; Macaca; Male; Nonverbal Communication; Phencyclidine; Social Behavior | 1973 |
'Hallucinogenic drugs and central transmitter substances'.
Topics: Amphetamine; Biogenic Amines; Brain; Dopamine; Dronabinol; Hallucinogens; Humans; Lysergic Acid Diethylamide; Mescaline; Norepinephrine; Parasympatholytics; Phencyclidine; Serotonin; Synaptic Transmission | 1972 |
Discriminative response control produced with hashish, tetrahydrocannabinols (delta 8-THC and delta 9-THC), and other drugs.
Topics: Amphetamine; Animals; Atropine; Avoidance Learning; Cannabis; Chlordiazepoxide; Chlorpromazine; Choice Behavior; Cocaine; Cues; Diazepam; Discrimination, Psychological; Dronabinol; Ketamine; Levallorphan; Male; Morphine; Pentobarbital; Phencyclidine; Physostigmine; Psilocybin; Rats; Scopolamine; Transfer, Psychology; Yohimbine | 1974 |
A rapid screening procedure for some "street drugs" by thin-layer chromatography.
Topics: Aldehydes; Amphetamine; Chromatography, Thin Layer; Hallucinogens; Humans; Indicators and Reagents; Lysergic Acid Diethylamide; Mescaline; Methods; p-Dimethylaminoazobenzene; Phencyclidine; Platinum; Psilocybin; Solvents; Strychnine; Substance-Related Disorders | 1972 |
Effects of various psychotomimetic agents on the EEG and acetylcholine release from the cerebral cortex of brainstem transected cats.
Topics: Acetylcholine; Amphetamine; Animals; Blood Pressure; Brain Stem; Cats; Cerebral Cortex; Dronabinol; Drug Combinations; Electrodes, Implanted; Electroencephalography; Glycolates; Hallucinogens; Heart Rate; Isomerism; Lysergic Acid Diethylamide; Male; Pentobarbital; Phencyclidine; Piperidines; Pyrrolidines | 1972 |
Treatment of acute hallucinogenic drug toxicity: specific pharmacological intervention.
Topics: Amphetamine; Atropa belladonna; Chlorpromazine; Dronabinol; Hallucinogens; Humans; Lysergic Acid Diethylamide; Mescaline; Parasympatholytics; Phencyclidine; Phenethylamines; Physostigmine; Plants, Medicinal; Plants, Toxic; Poisoning; Succinates; Tranquilizing Agents | 1973 |
Behavioural effects of some morphine antagonists and hallucinogens in the rat.
Topics: Amphetamine; Analgesics; Anesthetics; Animals; Ataxia; Atropine; Azocines; Behavior, Animal; Cyclazocine; Levallorphan; Lysergic Acid Diethylamide; Male; Mescaline; Morphine; Motor Activity; Movement Disorders; Nalorphine; Narcotic Antagonists; Pentazocine; Phencyclidine; Piperidines; Psilocybin; Psychopharmacology; Rats | 1968 |
Anorexia and hyperphagia produced by five pharmacologic classes of hallucinogens.
Topics: Amphetamine; Animals; Anorexia; Atropine; Dextroamphetamine; Dogs; Dronabinol; Feeding and Eating Disorders; Feeding Behavior; Female; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; Phenazocine; Phencyclidine | 1982 |
Genetic effects on PCP-induced stimulation in recombinant inbred strains of mice.
Topics: Amphetamine; Animals; Hybridization, Genetic; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Motor Activity; Phencyclidine; Phenethylamines; Scopolamine; Species Specificity | 1984 |
The effects of an in vivo administration of phencyclidine on sodium-dependent high affinity choline uptake in rat hippocampus and striatum in vitro.
Topics: Amphetamine; Animals; Behavior, Animal; Choline; Corpus Striatum; Drug Interactions; Haloperidol; Hippocampus; In Vitro Techniques; Male; Phencyclidine; Rats; Rats, Inbred Strains; Sodium; Synaptosomes | 1983 |
The clandestine drug laboratory situation in the United States.
Topics: 3,4-Methylenedioxyamphetamine; Acetone; Amphetamine; Drug and Narcotic Control; Humans; Illicit Drugs; Methamphetamine; Methaqualone; Pharmaceutical Preparations; Phencyclidine; Substance-Related Disorders; United States | 1983 |
Effects of phencyclidine, amphetamine and related compounds on dopamine release from and uptake into striatal synaptosomes.
Topics: Amphetamine; Animals; Benztropine; Corpus Striatum; Dopamine; Flupenthixol; In Vitro Techniques; Nomifensine; Phencyclidine; Potassium; Rats; Reserpine; Synaptosomes | 1984 |
Effects of phencyclidine on the release of radioactivity from rat striatal slices labeled with [3H]choline.
Topics: Acetylcholine; Amphetamine; Animals; Atropine; Calcium; Choline; Corpus Striatum; Dose-Response Relationship, Drug; Ergolines; Male; Oxotremorine; Pergolide; Phencyclidine; Rats; Rats, Inbred Strains | 1983 |
Ethanol intake increases during continuous administration of amphetamine and nicotine, but not several other drugs.
Topics: Alcohol Drinking; Amphetamine; Animals; Caffeine; Drinking Behavior; Drug Implants; Female; Haloperidol; Lysergic Acid Diethylamide; Mescaline; Nicotine; Phencyclidine; Rats; Secobarbital | 1983 |
Chronic phencyclidine, like amphetamine, produces a decrease in [3H]spiroperidol binding in rat striatum.
Topics: Amphetamine; Animals; Butyrophenones; Corpus Striatum; Depression, Chemical; In Vitro Techniques; Kinetics; Male; Phencyclidine; Rats; Rats, Inbred Strains; Spiperone | 1982 |
Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats.
Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Ataxia; Dose-Response Relationship, Drug; Humans; Male; Motor Activity; Phencyclidine; Rats; Stereotyped Behavior | 1981 |
Stimulation of synaptosomal tyrosine hydroxylation by phencyclidine in vitro.
Topics: Amphetamine; Animals; Dopamine; Dose-Response Relationship, Drug; Hydroxylation; In Vitro Techniques; Male; Phencyclidine; Rats; Synaptosomes; Temperature; Tyrosine | 1981 |
Drug-induced psychosis: emergency diagnosis and management.
Topics: Amphetamine; Emergency Medical Services; Hallucinogens; Humans; Lysergic Acid Diethylamide; Parasympatholytics; Phencyclidine; Physostigmine; Psilocybin; Psychoses, Substance-Induced; Sympathomimetics | 1981 |
Phencyclidine: effect on the accumulation of 3H-dopamine in synaptic vesicles.
Topics: Adenosine Triphosphate; Amphetamine; Animals; Dextroamphetamine; Dopamine; Kinetics; Magnesium; Phencyclidine; Reserpine; Swine; Synaptic Vesicles | 1980 |
Blockade of phencyclidine-induced hyperlocomotion by clozapine and MDL 100,907 in rats reflects antagonism of 5-HT2A receptors.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Excitatory Amino Acid Antagonists; Fluorobenzenes; Male; Motor Activity; Phencyclidine; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists | 1995 |
Pharmacological specificity of enhanced sensitivity to naltrexone in rats.
Topics: Amphetamine; Animals; Chlordiazepoxide; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Food; Male; Naltrexone; Narcotic Antagonists; Narcotics; Phencyclidine; Rats; Reinforcement Schedule; Stereoisomerism | 1993 |
The effects of haloperidol and clozapine on PCP- and amphetamine-induced suppression of social behavior in the rat.
Topics: Aggression; Amphetamine; Animals; Clozapine; Haloperidol; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Social Behavior | 1994 |
Substance abuse testing of urine by GC/MS in scanning mode evaluated by proficiency studies, TLC/GC, and EMIT.
Topics: Amphetamine; Barbiturates; Benzodiazepines; Cocaine; Dronabinol; Enzyme Multiplied Immunoassay Technique; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Mass Spectrometry; Narcotics; Phencyclidine; Predictive Value of Tests; Sensitivity and Specificity; Substance-Related Disorders | 1993 |
Acute reactions to drugs of abuse.
Topics: Acute Disease; Administration, Inhalation; Amphetamine; Cannabinoids; Central Nervous System Diseases; Cocaine; Drug Contamination; Hallucinogens; Humans; Hypnotics and Sedatives; Illicit Drugs; Narcotics; Nitric Oxide; Phencyclidine; Seizures; Substance-Related Disorders; Sympathomimetics | 1996 |
Quantitative trait loci contributing to phencyclidine-induced and amphetamine-induced locomotor behavior in inbred mice.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Excitatory Amino Acid Antagonists; Female; Genetic Markers; Mice; Mice, Inbred Strains; Motor Activity; Phencyclidine | 1996 |
A 5-year stability study of common illicit drugs in blood.
Topics: Amphetamine; Calibration; Cocaine; Codeine; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Longitudinal Studies; Methamphetamine; Morphine; Narcotics; Phencyclidine | 1995 |
Alterations in striatal dopamine overflow during rotational behavior induced by amphetamine, phencyclidine, and MK-801.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; Neostriatum; Phencyclidine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra | 1997 |
Reversal of phencyclidine-induced hyperactivity by glycine and the glycine uptake inhibitor glycyldodecylamide.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Mice; Motor Activity; Phencyclidine | 1997 |
Evaluation of Triage screening for drugs of abuse in postmortem blood and urine samples.
Topics: Amphetamine; Amphetamines; Antidepressive Agents, Tricyclic; Barbiturates; Benzodiazepines; Cannabinoids; Evaluation Studies as Topic; False Negative Reactions; False Positive Reactions; Humans; Narcotics; Phencyclidine; Postmortem Changes; Reagent Kits, Diagnostic; Substance-Related Disorders | 1997 |
Acute amphetamine and/or phencyclidine effects on the dopamine receptor specific binding in the rat brain.
Topics: Amphetamine; Animals; Brain; Central Nervous System Stimulants; Hallucinogens; Male; Phencyclidine; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1997 |
Adrenergic alpha2C-receptors modulate the acoustic startle reflex, prepulse inhibition, and aggression in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Aggression; Amphetamine; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Imidazoles; Male; Medetomidine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis; Neural Inhibition; Phencyclidine; Receptors, Adrenergic, alpha-2; Reflex, Startle; Social Behavior | 1998 |
Food restriction enhances the central rewarding effect of abused drugs.
Topics: Amphetamine; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Energy Intake; Excitatory Amino Acid Antagonists; Food Deprivation; Locomotion; Male; Nicotine; Nicotinic Agonists; Phencyclidine; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Substance-Related Disorders; Sympathomimetics | 1998 |
Determination of five abused drugs in nitrite-adulterated urine by immunoassays and gas chromatography-mass spectrometry.
Topics: Amphetamine; Cocaine; Dronabinol; Drug Contamination; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Morphine; Nitrites; Phencyclidine; Substance Abuse Detection; Sulfites | 1998 |
Increased discriminative stimulus potency of phencyclidine in C57B1/6 mice infected with the LP-BM5 retrovirus.
Topics: Adrenergic Agents; Amphetamine; Animals; Discrimination Learning; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Leukemia Virus, Murine; Male; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Phencyclidine; Psychomotor Performance; Sensitivity and Specificity; Time Factors | 1999 |
Rat strain differences in the ability to disrupt sensorimotor gating are limited to the dopaminergic system, specific to prepulse inhibition, and unrelated to changes in startle amplitude or nucleus accumbens dopamine receptor sensitivity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Amphetamine; Animals; Apomorphine; Dopamine; Dopamine Agonists; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Phencyclidine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Dopamine; Reflex, Startle; Species Specificity; Time Factors | 1999 |
The delayed effects of phencyclidine enhance amphetamine-induced behavior and striatal C-Fos expression in the rat.
Topics: Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Drug Synergism; Immunohistochemistry; Male; Phencyclidine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Immunoassay and GC-MS procedures for the analysis of drugs of abuse in meconium.
Topics: Amphetamine; Cocaine; Dronabinol; Enzyme Multiplied Immunoassay Technique; False Negative Reactions; Female; Fetus; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Morphine; Narcotics; Phencyclidine; Pregnancy; Reproducibility of Results; Substance Abuse Detection | 1999 |
Contrasting mechanisms of action and sensitivity to antipsychotics of phencyclidine versus amphetamine: importance of nucleus accumbens 5-HT2A sites for PCP-induced locomotion in the rat.
Topics: Amphetamine; Animals; Antipsychotic Agents; Area Under Curve; Binding, Competitive; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Frontal Lobe; Locomotion; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Phencyclidine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin | 1999 |
Pharmacological mechanisms mediating phencyclidine-induced apoptosis of striatopallidal neurons: the roles of glutamate, dopamine, acetylcholine and corticosteroids.
Topics: Acetylcholine; Adrenal Cortex Hormones; Amphetamine; Animals; Apoptosis; Behavior, Animal; Benzazepines; Biogenic Monoamines; Central Nervous System Stimulants; Cerebral Cortex; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Globus Pallidus; Glutamic Acid; Hormone Antagonists; Male; Mifepristone; Muscarinic Antagonists; Neostriatum; Neurons; Phencyclidine; Quinpirole; Rats; Rats, Sprague-Dawley; Scopolamine; Stress, Physiological | 2000 |
NMDA receptor antagonists acting at the glycineB site in rat models for antipsychotic-like activity.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Antimetabolites; Antipsychotic Agents; Binding Sites; Cycloleucine; Cycloserine; Disease Models, Animal; Dopamine Agents; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; Hallucinogens; Locomotion; Male; Phencyclidine; Phthalazines; Protein Structure, Tertiary; Psychotic Disorders; Pyrrolidinones; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 1999 |
Screening postmortem blood and tissues for nine classes [correction of cases] of drugs of abuse using automated microplate immunoassay.
Topics: Amphetamine; Anti-Anxiety Agents; Autopsy; Benzodiazepines; Body Fluids; Cannabinoids; Central Nervous System Stimulants; Cocaine; Enzyme-Linked Immunosorbent Assay; False Negative Reactions; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hypnotics and Sedatives; Illicit Drugs; Lysergic Acid Diethylamide; Methamphetamine; Microchemistry; Morphine; Narcotics; Phencyclidine; Radioimmunoassay; Sensitivity and Specificity; Substance-Related Disorders; Tissue Distribution | 1999 |
Psychotomimetics moderately affect dopamine receptor binding in the rat brain.
Topics: Amphetamine; Animals; Benzazepines; Brain; Central Nervous System Stimulants; Corpus Striatum; Dextroamphetamine; Hallucinogens; Lysergic Acid Diethylamide; Male; Nucleus Accumbens; Phencyclidine; Rats; Receptors, Dopamine; Spiperone; Tritium | 2000 |
The effects of phencyclidine pretreatment on amphetamine-induced behavior and c-Fos expression in the rat.
Topics: Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Gyrus Cinguli; Male; Motor Activity; Nucleus Accumbens; Phencyclidine; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2001 |
Atypical antipsychotic effects of quetiapine fumarate in animal models.
Topics: Amphetamine; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Disease Models, Animal; Female; Haloperidol; Immobilization; Male; Mice; Phencyclidine; Rats; Rats, Wistar; Schizophrenia; Schizophrenia, Paranoid | 2000 |
Differential effects of amphetamine and phencyclidine on the expression of growth-associated protein GAP-43.
Topics: Amphetamine; Animals; Biomarkers; Brain; Disease Models, Animal; Dopamine Agents; Dopamine Antagonists; Drug Administration Schedule; Excitatory Amino Acid Antagonists; GAP-43 Protein; Haloperidol; Male; Neostriatum; Neurons; Phencyclidine; Psychoses, Substance-Induced; Psychotic Disorders; Rats; Rats, Inbred Strains; RNA, Messenger | 2001 |
Continuous phencyclidine treatment induces schizophrenia-like hyperreactivity of striatal dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; Homovanillic Acid; Male; Motor Activity; Phencyclidine; Psychomotor Agitation; Rats; Rats, Sprague-Dawley; Schizophrenia | 2001 |
Natural segmentation of the locomotor behavior of drug-induced rats in a photobeam cage.
Topics: Algorithms; Amphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electronic Data Processing; Exploratory Behavior; Housing, Animal; Male; Mice; Models, Neurological; Motor Activity; Neuropharmacology; Normal Distribution; Phencyclidine; Photic Stimulation; Rats; Rats, Sprague-Dawley; Video Recording | 2001 |
The adenosine A2A agonist CGS 21680 reverses the reduction in prepulse inhibition of the acoustic startle response induced by phencyclidine, but not by apomorphine and amphetamine.
Topics: Acoustic Stimulation; Adenosine; Amphetamine; Animals; Apomorphine; Dopamine Agonists; Dopamine Uptake Inhibitors; Hallucinogens; Injections, Intraperitoneal; Male; Motor Activity; Phencyclidine; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reflex, Startle | 2001 |
NMDA antagonist effects on striatal dopamine release: microdialysis studies in awake monkeys.
Topics: Amphetamine; Animals; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Ketamine; Macaca mulatta; Magnetic Resonance Imaging; Male; Microdialysis; Neostriatum; Neurons; Nomifensine; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Wakefulness | 2002 |
Effects of repeated treatment with amphetamine or phencyclidine on working memory in the rat.
Topics: Amphetamine; Animals; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory, Short-Term; Phencyclidine; Rats; Rats, Sprague-Dawley | 2002 |
The effects of psychotomimetics and psychomotor stimulants on two schedules promoting response switching in the rat.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Atropine; Behavior, Animal; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Ethanol; Food; Hallucinogens; Lysergic Acid Diethylamide; Muscarinic Antagonists; Phencyclidine; Photic Stimulation; Rats; Rats, Long-Evans; Reinforcement Schedule; Scopolamine | 2002 |
Subchronic continuous phencyclidine administration potentiates amphetamine-induced frontal cortex dopamine release.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Dopamine; Drug Synergism; Excitatory Amino Acid Antagonists; Homovanillic Acid; Hyperkinesis; Male; Microdialysis; Nucleus Accumbens; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2003 |
Effect of amphetamine and phencyclidine on DNA-binding activities of serum response and dyad symmetry elements.
Topics: Amphetamine; Animals; Blotting, Western; Brain Chemistry; Central Nervous System Stimulants; DNA Transposable Elements; Electrophoretic Mobility Shift Assay; Genes, fos; Hallucinogens; Male; Phencyclidine; Proto-Oncogene Proteins c-fos; Rats | 2003 |
Influence of postweaning social isolation in the rat on brain development, conditioned behavior, and neurotransmission.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Avoidance Learning; Benzylamines; Brain; Carbachol; Central Nervous System Stimulants; Cholinergic Agonists; Conditioning, Psychological; Discrimination Learning; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Escape Reaction; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; Motor Activity; Neurons; Neurotransmitter Agents; Phencyclidine; Rats; Reaction Time; Serotonin; Serotonin Agents; Social Isolation; Stress, Physiological | 2003 |
Effects of haloperidol and clozapine on neuropeptide Y-like immunoreactivity in the nucleus accumbens and striatum of rats pretreated with psychostimulants.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Hallucinogens; Haloperidol; Immunohistochemistry; Male; Motor Activity; Neostriatum; Neuropeptide Y; Nucleus Accumbens; Phencyclidine; Rats; Rats, Wistar; Stereotyped Behavior | 2003 |
Phencyclidine exacerbates attentional deficits in a neurodevelopmental rat model of schizophrenia.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Attention; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Central Nervous System Stimulants; Choice Behavior; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Male; Motor Activity; Phencyclidine; Rats; Rats, Sprague-Dawley; Reaction Time; Schizophrenia | 2003 |
Differential role of serotonergic projections arising from the dorsal and median raphe nuclei in locomotor hyperactivity and prepulse inhibition.
Topics: 5,7-Dihydroxytryptamine; Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Carrier Proteins; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Radiation; Drug Interactions; Excitatory Amino Acid Antagonists; Hyperkinesis; Immunohistochemistry; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Motor Activity; Nerve Tissue Proteins; Neural Inhibition; Phencyclidine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex, Startle; Schizophrenia; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Time Factors | 2003 |
Enhancement of latent inhibition by two 5-HT2A receptor antagonists only when given at both pre-exposure and conditioning.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamine; Analysis of Variance; Animals; Association Learning; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Interactions; Fluorobenzenes; Inhibition, Psychological; Male; Phencyclidine; Phenols; Quinolines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior | 2003 |
Reversal of phencyclidine-induced dopaminergic dysregulation by N-methyl-D-aspartate receptor/glycine-site agonists.
Topics: Amphetamine; Animals; Behavior, Animal; Brain; Brain Chemistry; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Electrochemistry; Excitatory Amino Acid Agonists; Glycine; Male; Microdialysis; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Time Factors | 2004 |
Motor effects of amphetamine in rats pretreated with either dizocilpine or phencyclidine.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Motor Activity; Movement; Phencyclidine; Rats; Stereotyped Behavior; Time Factors | 2003 |
Psychotomimetic effects of drugs--a common pathway to schizophrenia?
Topics: Amphetamine; Animals; Central Nervous System Agents; Corpus Striatum; Dopamine and cAMP-Regulated Phosphoprotein 32; Frontal Lobe; Lysergic Acid Diethylamide; Mice; Models, Animal; Nerve Tissue Proteins; Phencyclidine; Phosphoproteins; Phosphorylation; Receptors, Dopamine; Schizophrenia; Signal Transduction | 2004 |
Progressive ratio performance following challenge with antipsychotics, amphetamine, or NMDA antagonists in adult rats treated perinatally with phencyclidine.
Topics: Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Male; Phencyclidine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule | 2004 |
Use of MDA (the "love drug") and methamphetamine in Toronto by unsuspecting users of ecstasy (MDMA).
Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamine; Canada; Cocaine; Dopamine Uptake Inhibitors; Drug Contamination; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Hallucinogens; Humans; Illicit Drugs; Male; Methamphetamine; Molecular Structure; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine | 2004 |
Functional dissociation between serotonergic pathways in dorsal and ventral hippocampus in psychotomimetic drug-induced locomotor hyperactivity and prepulse inhibition in rats.
Topics: Amphetamine; Animals; Hallucinogens; Hippocampus; Hyperkinesis; Male; Neural Inhibition; Neural Pathways; Phencyclidine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Serotonin | 2004 |
Sensitization to amphetamine, but not phencyclidine, disrupts prepulse inhibition and latent inhibition.
Topics: Amphetamine; Animals; Avoidance Learning; Conditioning, Psychological; Male; Mental Processes; Motor Activity; Neural Inhibition; Phencyclidine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia; Taste | 2005 |
Monoaminergic dysregulation in glutathione-deficient mice: possible relevance to schizophrenia?
Topics: Amphetamine; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Glutathione; Hallucinogens; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Microdialysis; Motor Activity; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin | 2005 |
Sensitization to amphetamine, but not PCP, impairs attentional set shifting: reversal by a D1 receptor agonist injected into the medial prefrontal cortex.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Conditioning, Operant; Discrimination Learning; Dopamine Uptake Inhibitors; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Motor Activity; Phencyclidine; Prefrontal Cortex; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 2005 |
Enhancement of AP-1 DNA-binding activity during amphetamine- and phencyclidine-mediated behaviour in rats.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Blotting, Western; Brain; Dopamine Agents; Drug Interactions; Electrophoretic Mobility Shift Assay; Excitatory Amino Acid Antagonists; Gene Expression; Immunoprecipitation; Male; Motor Activity; Phencyclidine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Time Factors; Transcription Factor AP-1 | 2006 |
Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: evidence for altered striatal function.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Biogenic Monoamines; Brain; Central Nervous System Stimulants; Conditioning, Operant; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Maze Learning; Methamphetamine; Mice; Mice, Knockout; Motor Activity; Phencyclidine; Phosphoric Diester Hydrolases | 2006 |
In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders.
Topics: Amino Acids; Amphetamine; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Cyclic S-Oxides; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mental Disorders; Mice; Molecular Structure; Motor Activity; Phencyclidine; Prefrontal Cortex; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Xanthenes | 2007 |
Evaluation of the mGlu8 receptor as a putative therapeutic target in schizophrenia.
Topics: Amphetamine; Animals; Anticonvulsants; Anxiety; Autoreceptors; Benzoates; Brain; Central Nervous System Stimulants; Dentate Gyrus; Disease Models, Animal; Electroshock; Glycine; Humans; Male; Mice; Mice, Knockout; Motor Activity; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Schizophrenia; Seizures; Synapses; Synaptic Transmission | 2007 |
Inactivation of the 5-HT(7) receptor partially blocks phencyclidine-induced disruption of prepulse inhibition.
Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Radiation; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Phencyclidine; Phenols; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Startle; Serotonin Antagonists; Sulfonamides | 2008 |
Characterization of interactions between phencyclidine and amphetamine in rodent prefrontal cortex and striatum: implications in NMDA/glycine-site-mediated dopaminergic dysregulation and dopamine transporter function.
Topics: Amphetamine; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Glycine; Male; Microdialysis; N-Methylaspartate; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2008 |
Behavioral characterization of mice deficient in the phosphodiesterase-10A (PDE10A) enzyme on a C57/Bl6N congenic background.
Topics: Amphetamine; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Depression; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Hot Temperature; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nucleotides, Cyclic; Pain Measurement; Phencyclidine; Phosphoproteins; Phosphoric Diester Hydrolases; Serotonin; Swimming | 2008 |
Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats.
Topics: Amphetamine; Animals; Attention; Behavior, Animal; Central Nervous System Stimulants; Cognition Disorders; Discrimination, Psychological; Dopamine; Frontal Lobe; Hallucinogens; Hyperkinesis; Male; Neostriatum; Phencyclidine; Rats; Rats, Long-Evans; Reflex, Startle; Schizophrenic Psychology; Social Behavior | 2008 |
Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion.
Topics: 5,7-Dihydroxytryptamine; Acoustic Stimulation; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Behavior, Animal; Brain; Hyperkinesis; Inhibition, Psychological; Male; Mice; Mice, Inbred C57BL; Phencyclidine; Reflex, Startle; Serotonin; Serotonin Agents; Stereotaxic Techniques | 2008 |
The antipsychotic potential of l-stepholidine--a naturally occurring dopamine receptor D1 agonist and D2 antagonist.
Topics: Amphetamine; Animals; Antipsychotic Agents; Avoidance Learning; Berberine; Brain Chemistry; Catalepsy; Central Nervous System Stimulants; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Genes, fos; Hallucinogens; Immunohistochemistry; Male; Mice; Mice, Knockout; Motor Activity; Phencyclidine; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2008 |
Amisulpride the 'atypical' atypical antipsychotic--comparison to haloperidol, risperidone and clozapine.
Topics: Amisulpride; Amphetamine; Animals; Antipsychotic Agents; Basal Ganglia; Behavior, Animal; Blood-Brain Barrier; Brain; Clozapine; Conditioning, Psychological; Haloperidol; Male; Models, Animal; Motor Activity; Phencyclidine; Prefrontal Cortex; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Serotonin; Risperidone; Sulpiride | 2008 |
A primate model of schizophrenia using chronic PCP treatment.
Topics: Amphetamine; Animals; Behavior, Animal; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Synergism; Female; Hallucinogens; Interpersonal Relations; Macaca fascicularis; Male; Phencyclidine; Schizophrenia; Social Behavior | 2008 |
Multiclass analysis of illicit drugs in plasma and oral fluids by LC-MS/MS.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Body Fluids; Calibration; Chromatography, High Pressure Liquid; Cocaine; Dronabinol; Humans; Illicit Drugs; Ketamine; Methamphetamine; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors | 2009 |
Repeated antipsychotic treatment progressively potentiates inhibition on phencyclidine-induced hyperlocomotion, but attenuates inhibition on amphetamine-induced hyperlocomotion: relevance to animal models of antipsychotic drugs.
Topics: Amphetamine; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Clozapine; Disease Models, Animal; Haloperidol; Hyperkinesis; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
Interactions between the glycine transporter 1(GlyT1) inhibitor SSR504734 and psychoactive drugs in mouse motor behaviour.
Topics: Amphetamine; Animals; Benzamides; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine Plasma Membrane Transport Proteins; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phencyclidine; Pilot Projects; Piperidines; Psychotropic Drugs; Receptors, N-Methyl-D-Aspartate | 2009 |
Altered mnemonic functions and resistance to N-METHYL-d-Aspartate receptor antagonism by forebrain conditional knockout of glycine transporter 1.
Topics: Amphetamine; Animals; Down-Regulation; Excitatory Postsynaptic Potentials; Female; Glycine; Glycine Plasma Membrane Transport Proteins; Hippocampus; Learning; Male; Memory; Mice; Mice, Knockout; Motor Activity; Mutation; Phencyclidine; Prosencephalon; Psychomotor Performance; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Synaptic Transmission | 2009 |
Are DBA/2 mice associated with schizophrenia-like endophenotypes? A behavioural contrast with C57BL/6 mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Phencyclidine; Phenotype; Reflex, Startle; Schizophrenia; Species Specificity | 2009 |
Inhibition of fatty-acid amide hydrolase and CB1 receptor antagonism differentially affect behavioural responses in normal and PCP-treated rats.
Topics: Amidohydrolases; Amphetamine; Animals; Autoradiography; Behavior, Animal; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Central Nervous System Stimulants; Cyclohexanols; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Hallucinogens; Interpersonal Relations; Male; Memory, Short-Term; Motor Activity; Neuropsychological Tests; Phencyclidine; Piperidines; Protein Binding; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Statistics, Nonparametric; Sulfur Isotopes; Time Factors | 2010 |
Subchronic phencyclidine in rats: alterations in locomotor activity, maze performance, and GABA(A) receptor binding.
Topics: Amphetamine; Animals; Corpus Striatum; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Frontal Lobe; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Hippocampus; Male; Maze Learning; Motor Activity; Muscimol; Phencyclidine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2010 |
Discordant behavioral effects of psychotomimetic drugs in mice with altered NMDA receptor function.
Topics: Amphetamine; Animals; Brain; Glutamate Decarboxylase; Hallucinogens; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neural Inhibition; Phencyclidine; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 2011 |
A comparison of the validity of gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry analysis of urine samples II: amphetamine, methamphetamine, (±)-3,4-methylenedioxyamphetamine, (±)-3,4-methylenedioxymethamphetamine, (
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, High Pressure Liquid; Dronabinol; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Methamphetamine; Phencyclidine; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry | 2010 |
Clozapine, but not olanzapine, disrupts conditioned avoidance response in rats by antagonizing 5-HT2A/2C receptors.
Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Avoidance Learning; Benzodiazepines; Clozapine; Conditioning, Classical; Dose-Response Relationship, Drug; Inhibition, Psychological; Male; Olanzapine; Phencyclidine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Time Factors | 2012 |
Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats.
Topics: Amphetamine; Animals; Benzodiazepines; Central Nervous System Stimulants; CHO Cells; Cognition Disorders; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperkinesis; Imidazoles; Male; Oocytes; Parvalbumins; Phencyclidine; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-A; Schizophrenia; Xenopus laevis | 2012 |
Glycine reuptake inhibitor RG1678: a pharmacologic characterization of an investigational agent for the treatment of schizophrenia.
Topics: Amphetamine; Animals; CA1 Region, Hippocampal; Cell Line; Central Nervous System Stimulants; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Hallucinogens; Humans; Long-Term Potentiation; Mice; Motor Activity; Phencyclidine; Piperazines; Rats; Rats, Sprague-Dawley; Sulfones; Synaptic Transmission | 2012 |
Effects of the selective 5-HT(7) receptor antagonist SB-269970 in animal models of psychosis and cognition.
Topics: Amphetamine; Animals; Animals, Outbred Strains; Cognition; Disease Models, Animal; Fluorobenzenes; Locomotion; Male; Phencyclidine; Phenols; Piperidines; Psychotic Disorders; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Recognition, Psychology; Serotonin Antagonists; Sulfonamides | 2012 |
NOGO-66 receptor deficient mice show slow acquisition of spatial memory task performance.
Topics: Alzheimer Disease; Amphetamine; Animals; Eating; Female; Fever; Hyperkinesis; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Myelin Proteins; Neuronal Plasticity; Nogo Proteins; Phencyclidine; Restraint, Physical; Schizophrenia; Time Factors | 2012 |
Differentiating the roles of mGlu2 and mGlu3 receptors using LY541850, an mGlu2 agonist/mGlu3 antagonist.
Topics: Amino Acids, Dicarboxylic; Amphetamine; Animals; Bridged Bicyclo Compounds; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Mice; Mice, Inbred ICR; Mice, Knockout; Motor Activity; Phencyclidine; Receptors, Metabotropic Glutamate; Synaptic Transmission | 2013 |
[Preliminary comparative study on the usefulness of instant-view'TM M-1 and Triage DOA in testing for drugs-of-abuse in forensic urine samples].
Topics: Amphetamine; Antidepressive Agents, Tricyclic; Barbiturates; Benzodiazepines; Cocaine; Forensic Toxicology; Humans; Phencyclidine; Reagent Kits, Diagnostic; Substance Abuse Detection; Substance-Related Disorders | 2012 |
Differential effects of estrogen and testosterone on auditory sensory gating in rats.
Topics: Amphetamine; Animals; Apomorphine; Auditory Perception; Body Weight; Central Nervous System Stimulants; Dopamine Agonists; Electrodes, Implanted; Electroencephalography; Electromyography; Estrogens; Evoked Potentials, Auditory; Female; Male; Orchiectomy; Organ Size; Ovariectomy; Phencyclidine; Rats; Rats, Sprague-Dawley; Sensory Gating; Sex Characteristics; Testosterone; Uterus | 2014 |
A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia.
Topics: Alanine; Amphetamine; Animals; Antipsychotic Agents; Anxiety; Benzodiazepines; Brain; Central Nervous System Stimulants; Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Olanzapine; Phencyclidine; Psychomotor Agitation; Schizophrenia; Social Behavior | 2014 |
A touch-screen based paired-associates learning (PAL) task for the rat may provide a translatable pharmacological model of human cognitive impairment.
Topics: Amphetamine; Animals; Cognition Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Ketamine; Male; Paired-Associate Learning; Phencyclidine; Psychomotor Performance; Random Allocation; Rats; Reaction Time; Scopolamine; Touch | 2014 |
Local inactivation of Gpr88 in the nucleus accumbens attenuates behavioral deficits elicited by the neonatal administration of phencyclidine in rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cognition Disorders; Discrimination, Psychological; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Gene Knockdown Techniques; Gene Silencing; Male; MicroRNAs; Motor Activity; Nucleus Accumbens; Phencyclidine; Random Allocation; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Schizophrenia; Social Behavior | 2015 |
Definitive Drug and Metabolite Screening in Urine by UPLC-MS-MS Using a Novel Calibration Technique.
Topics: Amphetamine; Benzodiazepines; Buprenorphine; Calibration; Chromatography, High Pressure Liquid; Cocaine; Humans; Limit of Detection; N-Methyl-3,4-methylenedioxyamphetamine; Opiate Alkaloids; Oxycodone; Phencyclidine; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry | 2016 |
Sex differences in psychotomimetic-induced behaviours in rats.
Topics: Amphetamine; Analysis of Variance; Animals; Cohort Studies; Cross-Over Studies; Female; Male; Models, Animal; Motor Activity; Phencyclidine; Prepulse Inhibition; Psychotropic Drugs; Random Allocation; Rats, Sprague-Dawley; Reflex, Startle; Sex Characteristics; Stereotyped Behavior | 2017 |
Acquisition of nicotine self-administration in amphetamine and phencyclidine models of schizophrenia: A role for stress?
Topics: Amphetamine; Animals; Disease Models, Animal; Learning; Male; Motor Activity; Nicotine; Nicotinic Agonists; Phencyclidine; Rats, Sprague-Dawley; Schizophrenia; Schizophrenic Psychology; Self Administration; Stress, Psychological; Tobacco Use Disorder | 2018 |
RP5063, an atypical antipsychotic drug with a unique pharmacologic profile, improves declarative memory and psychosis in mouse models of schizophrenia.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Cerebral Cortex; Conditioning, Operant; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Male; Memory; Mice, Inbred C57BL; Motor Activity; Neurotransmitter Agents; Phencyclidine; Psychotic Disorders; Random Allocation; Reversal Learning; Schizophrenia; Schizophrenic Psychology | 2017 |
Engineered D2R Variants Reveal the Balanced and Biased Contributions of G-Protein and β-Arrestin to Dopamine-Dependent Functions.
Topics: Amphetamine; Animals; Behavior, Animal; beta-Arrestins; Cocaine; Dopamine; Female; Genetic Vectors; Haloperidol; Heterotrimeric GTP-Binding Proteins; Male; Mice; Mice, Knockout; Mice, Transgenic; Phencyclidine; Receptors, Dopamine D2; Signal Transduction | 2018 |
Behavioural and computational methods reveal differential effects for how delayed and rapid onset antidepressants effect decision making in rats.
Topics: Acoustic Stimulation; Amphetamine; Analgesics; Animals; Antidepressive Agents; Association Learning; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Decision Making; Depressive Disorder, Major; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluoxetine; Ketamine; Male; Models, Biological; Phencyclidine; Rats; Reaction Time; Time Factors | 2017 |
A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission.
Topics: Abnormalities, Multiple; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Chromosome Deletion; Chromosomes, Human, Pair 1; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Excitatory Amino Acid Antagonists; Megalencephaly; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Phencyclidine; Phenotype; Prepulse Inhibition; Quinpirole; Receptors, Dopamine; Schizophrenia; Ventral Tegmental Area | 2017 |
Investigating the role of mGluR2 versus mGluR3 in antipsychotic-like effects, sleep-wake architecture and network oscillatory activity using novel Han Wistar rats lacking mGluR2 expression.
Topics: Amino Acids; Amphetamine; Animals; Antipsychotic Agents; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cyclohexanes; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Gamma Rhythm; Locomotion; Male; Motor Activity; Mutation; Phencyclidine; Rats; Receptors, Metabotropic Glutamate; Sleep; Theta Rhythm; Wakefulness | 2018 |
The risk of emerging new psychoactive substances: The first fatal 3-MeO-PCP intoxication in The Netherlands.
Topics: Adult; Amphetamine; Blood Alcohol Content; Chromatography, Liquid; Designer Drugs; Humans; Male; Mass Spectrometry; Netherlands; Phencyclidine; Psychotropic Drugs; Substance-Related Disorders | 2019 |
Reassessment of amphetamine- and phencyclidine-induced locomotor hyperactivity as a model of psychosis-like behavior in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Akathisia, Drug-Induced; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Disease Models, Animal; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Male; Phencyclidine; Psychoses, Substance-Induced; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 2022 |