amphetamine has been researched along with oxidopamine in 331 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (16.62) | 18.7374 |
| 1990's | 110 (33.23) | 18.2507 |
| 2000's | 107 (32.33) | 29.6817 |
| 2010's | 55 (16.62) | 24.3611 |
| 2020's | 4 (1.21) | 2.80 |
| Authors | Studies |
|---|---|
| Kunow, M; Löschmann, PA; Wachtel, H | 1 |
| Damsma, G; De Boer, P; Schram, Q; Stoof, JC; Westerink, BH; Zaagsma, J | 1 |
| Frodl, EM; Kupsch, A; Oertel, WH; Sauer, H; ten Bruggencate, G | 1 |
| Blunt, S; Jenner, P; Marsden, CD; Sawada, T; Takeuchi, Y | 2 |
| Boldry, RC; Layer, RT; Uretsky, NJ; Wallace, LJ | 1 |
| Castañeda, E; Fiorino, D; Mittleman, G; Whishaw, IQ | 1 |
| Cole, BJ; Robbins, TW | 1 |
| Cadet, JL; Zhu, SM | 1 |
| Angulo, J; Cadet, JL; Dollison, A; Fahn, S; Kujirai, K; Zhu, SM | 1 |
| Carey, RJ | 1 |
| Carman, LS; Gage, FH; Shults, CW | 1 |
| Collier, TJ; Sladek, JR; Steece-Collier, K; Yurek, DM | 1 |
| McKenzie, JS; Shafton, AD; Stewart, CA | 1 |
| Castañeda, E; Robinson, TE; Whishaw, IQ | 1 |
| Bédard, PJ; Di Paolo, T; Gagnon, C; Gaudin, DP; Rioux, L | 1 |
| Abreu, M; Ferkany, J; French, ED; Levenson, S | 1 |
| Bédard, PJ; Di Paolo, T; Gagnon, C; Gaudin, D; Martinoli, MG; Pelletier, G; Rioux, L | 1 |
| Gale, K; Meloni, R | 2 |
| Bédard, PJ; Bui, LK; DiPaolo, T; Gaudin, DP; Grégoire, L; Rioux, L | 1 |
| Hansen, S; Harthon, C; Löfberg, L; Svensson, K; Wallin, E | 1 |
| Abrous, DN; Herman, JP; Le Moal, M; Rivet, JM | 1 |
| Clarke, PB; Franklin, KB; White, NM | 1 |
| Abrous, N; Aunis, D; Decombe, R; Herman, JP; Peschanski, M; Rivot, JP | 1 |
| Becker, JB | 1 |
| Dunnett, SB; Rogers, DC | 1 |
| Blunt, SB; Jenner, P; Marsden, CD | 1 |
| Becker, JB; Curran, EJ; Freed, WJ; Poltorak, M | 1 |
| Annett, LE; Baker, HF; Dunnett, SB; Marsden, CD; Martel, FL; Ridley, RM; Rogers, DC | 1 |
| Gale, K; Meloni, R; Segovia, J | 1 |
| Bankiewicz, KS; Ewing, SE; Perese, DA; Ulman, J; Viola, J | 1 |
| Gold, LH; Hubner, CB; Koob, GF | 1 |
| Brinsfield, KH; Matsumoto, RR; Patrick, RL; Walker, JM | 1 |
| Borisov, MM | 1 |
| French, ED | 1 |
| Kamo, H; Kim, SU; McGeer, PL; Shin, DH | 1 |
| Matsubara, K; Matsushita, A | 1 |
| Kelly, E; Nahorski, SR | 1 |
| Amalric, M; Koob, GF; Swerdlow, NR; Vaccarino, FJ | 1 |
| Freedman, R; Hoffer, BJ; Johnson, SW | 1 |
| Björklund, A; Brundin, P; Gage, FH; Isacson, O; Prochiantz, A | 1 |
| Blackburn, J; White, NM | 1 |
| Herrera-Marschitz, M; Ungerstedt, U; Zetterström, T | 1 |
| de Villiers, AS; Douglas, RJ; Kellaway, L; Mintz, M; Tomer, R | 1 |
| Silverman, PB | 2 |
| Boldry, R; Chang, YA; Farooqui, T; Miller, D; Sabol, B; Uretsky, N | 1 |
| Amalric, M; Koob, GF; Swerdlow, NR | 1 |
| Elworthy, PM | 1 |
| Leccese, AP; Lyness, WH | 1 |
| Boismare, F; Daoust, M; Moore, N; Saligaut, C | 1 |
| Deminière, JM; Le Moal, M; Simon, H; Taghzouti, K; Tassin, JP | 1 |
| Freedman, W; McElligott, JG | 1 |
| Cadafalch, J; Casas, M; Cobos, A; Ferré, S; Grau, JM; Jané, F | 1 |
| Abrous, N; Herman, JP; Hertting, G; Jackisch, R; Le Moal, M; Lupp, A | 1 |
| Björklund, A; Starke, K; Wichmann, T; Wictorin, K | 1 |
| Arnt, J | 2 |
| Jenner, P; Kelly, E; Marsden, CD | 1 |
| Bickford, P; Freedman, R; Hattox, S; Johnson, SW; Murphy, R; Sorensen, SM | 1 |
| Oades, RD | 1 |
| Hauger, RL; Hulihan-Giblin, B; Janowsky, A; Paul, SM | 1 |
| Arbilla, S; Baud, P; Cantrill, RC; Langer, SZ; Scatton, B | 1 |
| Choulli, K; Herman, JP; Le Moal, M | 1 |
| Jackson, EA; Kelly, PH; Schultz, L | 1 |
| Alloway, KD; Rebec, GV | 1 |
| Cohen, R; Pert, A; Siever, L | 1 |
| Morgan, M; Smith, JR | 1 |
| Martin, GE; Papp, NL | 1 |
| Arnt, J; Hyttel, J | 1 |
| Dravid, A; Enz, A; Frei, P; Jaton, AL | 1 |
| Arnt, J; Hyttel, J; Larsen, JJ | 1 |
| Horsburgh, RJ; Lees, GJ | 1 |
| Cubells, J; Gardner, EL; Hirschhorn, ID; Hittner, D; Makman, MH | 1 |
| Czekajewski, J; Fung, YK; Kober, KJ; Potter, EA; Torello, MW | 1 |
| Braestrup, C; Nielsen, EB; Nielsen, M | 1 |
| Iversen, SD; Joyce, EM | 1 |
| Herman, JP; Le Moal, M; Stinus, L | 1 |
| Jenner, P; Leigh, PN; Marsden, CD; Reavill, C | 1 |
| Mitchell, I; Redgrave, P | 1 |
| Ashcroft, GW; Makanjuola, RO | 1 |
| Fung, YK; Uretsky, NJ | 1 |
| Dayton, MA; Ewing, AG; Wightman, RM | 1 |
| Bianchine, JR; Schwarz, RD; Uretsky, NJ | 1 |
| Currie, RW; Paul, ML; Robertson, HA | 1 |
| Bédard, PJ; Côté, PY; Grégoire, L; Parent, A; Roy, E | 1 |
| Ossowska, K | 1 |
| Björklund, A; Cenci, MA; Cunningham, MG; McKay, RD; Nikkhah, G | 1 |
| Morgenstern, R; Reum, T; Schäfer, U | 1 |
| Arbuthnott, GW; Duggan, AW; Furmidge, LJ | 1 |
| Boix, F; Fornaguera, J; Huston, JP; Schwarting, RK | 1 |
| Björklund, A; Cunningham, MG; McKay, R; Nikkhah, G | 1 |
| Akil, H; Badiani, A; Morano, MI; Robinson, TE | 1 |
| Badiani, A; Browman, KE; Robinson, TE | 1 |
| Abrous, DN; Herman, JP; Le Moal, M | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Snoddy, HD | 1 |
| Arendash, GW; Dunn, AJ; Oestreicher, E; Olanow, CW; Riederer, P; Sengstock, GJ | 1 |
| Day, JC; Fibiger, HC; Tham, CS | 1 |
| Barker, R; Dunnett, SB | 1 |
| Chase, TN; Engber, TM; Kask, AM; Papa, SM | 1 |
| Amato, G; Crescimanno, G; Emmi, A | 1 |
| Björklund, A; Cenci, MA | 2 |
| Bankiewicz, KS; Oldfield, EH; Plunkett, RJ; Wang, J | 1 |
| Björklund, A; Cunningham, MG; Jödicke, A; Knappe, U; Nikkhah, G | 1 |
| Gash, DM; Sakai, K | 1 |
| Costantini, LC; Snyder-Keller, AM; Vozza, BM | 1 |
| Bankiewicz, KS; de Jesus, S; Sheng, J; Takubo, H; Thomas, J; Wang, J | 1 |
| Morgenstern, R; Reum, T | 1 |
| Blount, JP; Conrad, JA; Kondoh, T; Low, WC; Pundt, LL | 1 |
| Camp, DM; Chan, EM; Mocsary, Z; Noordhoorn, M; Robinson, TE; Whishaw, IQ | 1 |
| Abrous, DN; Annett, LE; Dunnett, SB; Reading, PJ; Tharumaratnam, D; Torres, EM | 1 |
| Basso, MA; Evinger, C; Strecker, RE | 1 |
| Albin, RL; Becker, JB; Curran, EJ | 1 |
| Engel, JA; Fahlke, C; Hansen, S; Hård, E | 1 |
| Amalric, M; Nieoullon, A; Ouagazzal, A | 1 |
| Fraser, A; Sullivan, RM; Szechtman, H | 1 |
| Hipkens, SB; Yurek, DM | 1 |
| Brock, S; Clayton, J; Gerhardt, GA; Hoffer, BJ; Hudson, JL; Masserano, J; Strömberg, I; van Horne, CG | 1 |
| Asari, S; Date, I; Furuta, T; Ohmoto, T; Sakai, K; Yoshimoto, Y; Zhou, J | 1 |
| Abrous, DN; Dunnett, SB; Torres, EM | 1 |
| Abrous, DN; Dunnett, SB; Shaltot, AR; Torres, EM | 1 |
| Parker, BA; Sullivan, RM; Szechtman, H | 1 |
| Brecknell, JE; Du, JS; Dunnett, SB; Fawcett, JW; Fidler, PS; Haque, NS; Hlavin, ML; Muir, EM | 1 |
| Abrous, DN; Le Moal, M; Simon, H | 1 |
| Guerra, MJ; Labandeira-Garcia, JL; Liste, I; Lopez-Martin, E; Rozas, G | 1 |
| Kimber, T; Martin, D; Shults, CW | 1 |
| Earl, CD; Kupsch, A; Morgenstern, R; Oertel, WH; Reum, T; Sautter, J; Xie, JX | 1 |
| Earl, CD; Kupsch, A; Marburger, A; Morgenstern, R; Oertel, WH; Sautter, J; Schönfuss, D; Strecker, S; Yang, Z | 1 |
| Castañeda, E; Davis, DA; Elson, HJ; Neisewander, JL; Sussman, AN | 1 |
| Castañeda, E; MacBeth, T; Tran-Nguyen, LT | 1 |
| Barnéoud, P; Boireau, A; Doble, A; Dubédat, P; Mazadier, M; Miquet, JM; Parmentier, S | 1 |
| Björklund, A; Lee, CS; Sauer, H; Winkler, C | 1 |
| Hong, M; Mendez, I; Sadi, D | 1 |
| Böhme, V; Moser, A; Nobbe, F; Siebecker, F | 1 |
| Finlay, JM; King, D; Zigmond, MJ | 1 |
| Labandeira García, JL; Rozas, G | 1 |
| Costantini, LC; Snyder-Keller, A | 1 |
| Badiani, A; Camp, DM; Robinson, TE | 1 |
| Akerman, KE; Ehsan, E | 1 |
| Caldwell, MA; Dunnett, SB; Karmiol, S; Rosser, AE; Shen, J; Svendsen, CN; ter Borg, MG; Tyers, P | 1 |
| Brundin, P; Cameron, RM; Duan, WM; Widner, H | 1 |
| Schroeder, SR; Stodgell, CJ; Tessel, RE; Van Keuren, KR | 1 |
| Armengol, JA; Espejo, EF; López-Barneo, J; Montoro, RJ | 1 |
| Brener, J; Liu, X; Strecker, RE | 1 |
| Evtouchenko, L; Guzman, R; Meyer, M; Seiler, RW; Spenger, C; Wagner, B; Widmer, HR | 1 |
| Agid, Y; Dziewczapolski, G; García, MC; Gershanik, O; Menalled, LB; Murer, MG; Raisman-Vozari, R | 1 |
| Guerra, MJ; Labandeira-Garcia, JL; Lopez-Martin, E; Rodriguez, J; Rozas, G | 1 |
| Björklund, A; Kirik, D; Rosenblad, C | 1 |
| Jacques, DB; Kopyov, O; Olds, ME | 5 |
| Kim, JH; Meeker, D; Vezina, P | 1 |
| Infante, C; Monari, M; Motles, E | 1 |
| Akil, H; Badiani, A; Day, HE; Oates, MM; Robinson, TE; Watson, SJ | 2 |
| Bardwaj, L; Bohn, MC; Chang, YN; Chiang, YL; Choi-Lundberg, DL; Crippens, D; Davidson, BL; Lin, Q; Qian, J; Schallert, T | 1 |
| Clarke, PB; Louis, M | 1 |
| Asin, KE; Wirtshafter, D | 1 |
| Chang, JW; Kang, UJ; Wachtel, SR; Young, D | 1 |
| Björklund, A; Devaux, B; Kirik, D; Moffat, B; Phillips, HS; Rosenblad, C | 1 |
| Damhaut, P; Dethy, S; Goldman, S; Laute, MA | 1 |
| Kinney, GG; Saywell, KL; Tricklebank, MD; Wilkinson, LO | 1 |
| Klein, RL; Lewis, MH; Meyer, EM; Muzyczka, N | 1 |
| Gentsch, C; Spooren, WP; Waldmeier, P | 1 |
| Abrous, DN; Aubin, N; Barnéoud, P; Descombris, E | 1 |
| Granata, R; Jenner, P; Laboyrie, P; Poewe, W; Puschban, Z; Quinn, NP; Scherfler, C; Wenning, GK | 1 |
| Brownell, AL; Cavagna, F; Coyle, JT; Iris Chen, YC; Jenkins, BG; Livni, E; Nguyen, TV; Rosen, BR | 1 |
| Baker, KA; Hong, M; Mendez, I; Sadi, D | 2 |
| Baker, KA; Hong, M; Mendez, I | 1 |
| Badiani, A; Browman, KE; Crombag, HS; Mueller, H; Robinson, TE | 1 |
| McGeer, EG; Stoessl, AJ; Van Kampen, JM | 1 |
| Badiani, A; Browman, KE; Fraioli, S; Oates, MM; Ostrander, MM; Robinson, TE; Wolf, ME; Xue, CJ | 1 |
| Charlton, CG; Lamango, NS | 1 |
| Cross, AJ; Georger, M; Howell, A; Hudzik, TJ | 1 |
| Cardinal, RN; Everitt, BJ; Parkinson, JA | 1 |
| Gray, JA; Grigoryan, GA; Joseph, MH; Moran, PM; Peters, SL; Young, AM | 1 |
| Akil, H; Badiani, A; Day, HE; Oates, MM; Robinson, TE; Uslaner, JM; Vittoz, NM; Watson, SJ | 1 |
| Höglinger, GU; Meyer, M; Oertel, WH; Sautter, J; Seiler, RW; Spenger, C; Widmer, HR | 1 |
| Behzadi, G; Roghani, M | 1 |
| Bardo, MT; Margulies, JE; Mattingly, BA; Robinet, PM | 1 |
| Björklund, A; Georgievska, B; Kirik, D; Rosenblad, C | 1 |
| Birkestrand, BR; Chen, R; Fowler, SC; Moss, SJ; Vorontsova, E; Wang, G; Zarcone, TJ | 1 |
| Kelsoe, JR; Niculescu, AB | 1 |
| Hamilton, GS; Hicks, TP; Poulter, MO; Steiner, JP; Zhang, C | 1 |
| Blandini, F; Fancellu, R; Greenamyre, JT; Nappi, G | 1 |
| Falkenstein, G; Nikkhah, G; Rosenthal, C | 1 |
| Baird, AL; Dunnett, SB; Jeyasingham, RA; Meldrum, A | 1 |
| Crocker, SJ; Korneluk, RG; Lee, CJ; Liston, P; MacKenzie, A; Nicholson, DW; Park, DS; Robertson, GS; Roy, S; Thompson, CS; Wigle, N; Xu, D | 1 |
| Bardo, MT; Robinet, PM | 1 |
| Boules, M; Fauq, A; McCormick, D; Richelson, E; Warrington, L | 1 |
| Shults, CW; Tsuboi, K | 1 |
| Andersson, T; Bjorklund, LM; Brownell, AL; Chen, IY; Chung, S; Isacson, O; Jenkins, BG; Kim, KS; McNaught, KS; Sánchez-Pernaute, R; Wahlestedt, C | 1 |
| Metz, GA; Whishaw, IQ | 1 |
| Alcaro, A; Cabib, S; Orsini, C; Puglisi-Allegra, S; Ventura, R | 1 |
| Geyer, MA; Pitcher, LK; Powell, SB; Preece, MA; Reynolds, GP; Swerdlow, NR | 1 |
| Balcioglu, A; Tarazi, FI; Zhang, K | 1 |
| Cauli, O; Morelli, M; Pinna, A; Valentini, V | 1 |
| Clarke, PB; Sellings, LH | 2 |
| Drago, J; Finkelstein, DI; Horne, MK; Krstew, EV; Lawrence, AJ; Parish, CL; Stanic, D; Zhu, WM | 1 |
| Akil, H; Badiani, A; Day, HE; Norton, CS; Ostrander, MM; Robinson, TE; Watson, SJ | 1 |
| Albin, RL; Desmond, TJ; Frey, KA; Kemmerer, ES; Kilbourn, MR | 1 |
| Alcaro, A; Cabib, S; Conversi, D; Mandolesi, L; Puglisi-Allegra, S; Ventura, R | 1 |
| Bizot, JC; Colpaërt, F; Drouin, C; Glowinski, J; Marien, M; Tassin, JP; Villégier, AS | 1 |
| Bergman, J; Eskola, O; Forsback, S; Grönroos, T; Haapalinna, A; Haaparanta, M; Marjamäki, P; Niemi, R; Rinne, J; Solin, O | 1 |
| Bastia, E; Chen, JF; Fredduzzi, S; Moratalla, R; Ongini, E; Schwarzschild, MA; Yu, L | 1 |
| Avale, ME; Falzone, TL; Gelman, DM; Grandy, DK; Low, MJ; Rubinstein, M | 1 |
| Aebischer, P; Sajadi, A; Schneider, BL | 1 |
| Caraballo, I; El Banoua, F; Fernandez-Espejo, E; Ferrer, B; Flores, JA; Galan-Rodriguez, B; Rodriguez de Fonseca, F | 1 |
| Aubert-Pouessel, A; Benoit, JP; Clavreul, A; Jollivet, C; Menei, P; Montero-Menei, CN; Venier-Julienne, MC | 1 |
| Date, I; Hamada, H; Kobayashi, K; Matsui, T; Miyoshi, Y; Muraoka, K; Shingo, T; Takeuchi, A; Yano, A; Yasuhara, T | 1 |
| Camargo, MD; Collier, TJ; Pitzer, MR; Sortwell, CE | 1 |
| Schmidt, WJ; Srinivasan, J | 1 |
| Ebinger, G; Jonkers, N; Michotte, Y; Sarre, S; Van Hemelrijck, A; Yuan, H | 1 |
| Moroz, IA; Peciña, S; Schallert, T; Stewart, J | 1 |
| Avale, ME; Nemirovsky, SI; Raisman-Vozari, R; Rubinstein, M | 1 |
| Carlsson, T; Georgievska, B; Kirik, D; Lacar, B; Winkler, C | 1 |
| Date, I; Kameda, M; Kobayashi, K; Matsui, T; Miyoshi, Y; Muraoka, K; Shingo, T; Takeuchi, A; Wenji, Y; Yano, A; Yasuhara, T | 1 |
| Dalley, JW; Robbins, TW; Theobald, DE; Winstanley, CA | 1 |
| Akiba, L; Akita, H; Hoka, S; Jitsuki, S; Noda, K; Ogata, M; Ogura, T; Saji, M | 1 |
| Date, I; Hamada, H; Kameda, M; Matsui, T; Miyoshi, Y; Muraoka, K; Nishio, S; Shingo, T; Takeuchi, A; wen Ji, Y; Yano, A; Yasuhara, T | 1 |
| Agrawal, AK; Ahmad, AS; Ahmad, M; Ansari, MA; Chaturvedi, RK; Ishrat, T; Islam, F; Khan, MB; Saleem, S; Yousuf, S | 1 |
| Baker, KA; Mendez, I | 1 |
| Bourke, D; Finkelstein, DI; Henderson, JM; Horne, MK; Patch, J; Stanic, D; Tomas, D | 1 |
| Bohn, MC; Kozlowski, DA; Smith, AD; Zigmond, MJ | 1 |
| Fjord-Larsen, L; Grønborg, M; Johansen, JL; Kusk, P; Rosenblad, C; Tornøe, J; Wahlberg, LU | 1 |
| Brundin, P; Iancu, R; Mohapel, P; Paul, G | 1 |
| Mohanakumar, KP; Saravanan, KS; Sindhu, KM | 1 |
| Dooley, PC; Finkelstein, DI; Ilic, M; Sliwinski, A; Stanic, D; West, JM | 1 |
| Agari, T; Borlongan, CV; Date, I; Hamada, H; Hayase, H; Kameda, M; Muraoka, K; Shingo, T; Wen Ji, Y; Yasuhara, T | 1 |
| Doering, LC; Kirkham, DL; Meissner, KK | 1 |
| Johansson, S; Lee, IH; Olson, L; Spenger, C | 1 |
| Benabid, AL; Berger, F; Buggia, V; Gilbert, F; Lévesque, D; Sgambato-Faure, V | 1 |
| Ericson, C; Georgievska, B; Lundberg, C | 1 |
| Castro, MG; Dunnett, SB; Lowenstein, PR; Monville, C; Torres, EM | 1 |
| Brundin, P; Petersén, A; Poewe, W; Puschban, Z; Stefanova, N; Wenning, GK; Winkler, C | 1 |
| Hosman, K; Kempermann, G; Kupsch, A; Petrus, DS; Siebert, E; Steiner, B; Winter, C | 1 |
| Brundin, P; Cenci, MA; Lane, EL; Winkler, C | 1 |
| Brown-Borg, HM; Dhanasekaran, M; Manyam, BV; Tharakan, B | 1 |
| Schober, R; Schwarz, J; Schwarz, SC; Storch, A; Wittlinger, J | 1 |
| Clarke, K; Davies, CH; Forbes, IT; Gribble, A; Hill, M; Jones, DN; Newson, M; Reavill, C; Rourke, C; Scott, C; Westaway, J; Wood, MD | 1 |
| Botterman, BR; Martinez, TN; McCoy, MK; Ruhn, KA; Smith, CG; Szymkowski, DE; Tansey, KE; Tansey, MG | 1 |
| Akamine, S; Fang, X; Namba, H; Sugiyama, K | 1 |
| Aceves, J; Anaya-Martinez, V; Erlij, D; Martinez-Fong, D; Martinez-Marcos, A | 1 |
| Chiang, YH; Lin, SZ; Zhou, FC | 1 |
| Bortel, A; Brus, R; Dabrowska, J; Drosik, M; Kostrzewa, RM; Kwiecinski, A; Nowak, P; Opara, J; Oswiecimska, J | 1 |
| Givrad, TK; Holschneider, DP; Maarek, JM; Sadler, TR; Yang, J | 1 |
| Juckel, G; Klein, J; Kupsch, A; Lee, T; Morgenstern, R; Mundt, A; Petrus, D; von Rumohr, A; Winter, C | 1 |
| Barber, AE; Beres, AJ; Ebert, AD; Svendsen, CN | 1 |
| Hong, M; Mendez, I; Mukhida, K; Quinn, M; Sadi, D | 1 |
| Barker, RA; Kuan, WL; Zhao, JW | 1 |
| Berger, SP; Brudney, EG; Johnson, SW; Meshul, CK; Paquette, MA; Putterman, DB | 1 |
| Kääriäinen, TM; Kekki, H; Lecklin, A; Lehtonen, S; Männistö, PT; Nenonen, T; Ossola, B; Piltonen, M; Raasmaja, A | 1 |
| Allbutt, H; Henderson, J; Johnston, C; Kassiou, M; van Dijk, A | 1 |
| Jensen, P; Meyer, M; Pedersen, EG; Widmer, HR; Zimmer, J | 1 |
| Blesch, A; Martinez, TN; McAlpine, FE; McCoy, MK; Ruhn, KA; Tansey, MG | 1 |
| Ferrario, JE; Gershanik, OS; Larramendy, C; Murer, MG; Saborido, MD; Taravini, IR | 1 |
| Collier, TJ; Freeman, TB; McGuire, SO; Meredith, G; Soderstrom, KE; Sortwell, CE; Steece-Collier, K; Wu, Q | 1 |
| Brundin, P; Cenci, MA; Lane, EL; Soulet, D; Vercammen, L | 1 |
| Antonelli, T; Cassano, T; Cuomo, V; Dipasquale, P; Ferraro, L; Gaetani, S; Giuffrida, A; Laconca, L; Macheda, T; Morgese, MG | 1 |
| Galiñanes, GL; Murer, MG; Taravini, IR | 1 |
| Anastasía, A; de Erausquin, GA; Mascó, DH; Torre, L | 1 |
| Bordia, T; Huang, LZ; Michael McIntosh, J; Parameswaran, N; Quik, M | 1 |
| Brundin, P; Cenci, MA; Lane, EL | 1 |
| Castañeda, E; Hutchings, JE; Marsh, ST; Paquette, MA | 1 |
| Andereggen, L; Ducray, AD; Guzman, R; Meyer, M; Widmer, HR | 1 |
| Brundin, P; Cenci, MA; Lane, EL; Vercammen, L | 1 |
| García-Gutiérrez, MS; Ledent, C; Leiva, C; Leza, JC; Manzanares, J; Molina, JA; Pérez-Nievas, BG; Pérez-Rial, S | 1 |
| Agari, T; Baba, T; Date, I; Fujino, H; Furuta, T; Jing, M; Kadota, T; Kikuchi, Y; Kondo, A; Kuramoto, S; Miyoshi, Y; Morimoto, T; Obata, F; Shingo, T; Tajiri, N; Takeda, I; Tayra, JT; Wang, F; Yasuhara, T; Yuan, W | 1 |
| Eckart, MT; Huelse-Matia, MC; McDonald, RS; Schwarting, RK | 1 |
| Baba, T; Date, I; Kadota, T; Kameda, M; Kikuchi, Y; Kondo, A; Miyoshi, Y; Shingo, T; Tajiri, N; Tayra, JT; Wang, F; Yasuhara, T; Yuan, WJ | 1 |
| Björklund, A; Draxler, P; Grealish, S; Mattsson, B | 1 |
| Cass, WA; Peters, LE | 1 |
| Fernandez-Espejo, E; Flores, JA; Gonzalez-Aparicio, R | 1 |
| Bankiewicz, KS; Fong, LK; Forsayeth, J; Gregory, PD; Guschin, D; Kells, AP; Laganiere, J; Lai, JT; Meng, X; Paschon, DE; Rebar, EJ; Yu, Q; Zhang, HS | 1 |
| Cumming, P; Kjaerby, C; Knudsen, GM; Palner, M | 1 |
| Cassaday, HJ; Marsden, CA; Nelson, AJ; Thur, KE | 1 |
| Falk, T; Gonzalez, RT; McCourt, AD; Sherman, SJ; Yee, BJ; Yue, X; Zhang, S | 1 |
| Cabrera, R; Casas, S; Escudero, C; García, S; Nanfaro, F; Yunes, R | 1 |
| Cunningham, RL; Giuffrida, A; Macheda, T; Poteet, E; Roberts, JL; Singh, M; Watts, LT | 1 |
| Bonhaus, DW; McFarland, K; Price, DL | 1 |
| Chao, OY; Huston, JP; Mattern, C; Nikolaus, S; Pum, ME; Ruocco, LA; Silva, AM; Wessler, J | 1 |
| Chao, OY; Huston, JP; Li, JS; Pum, ME | 1 |
| Björklund, A; Carta, M; Shin, E; Tronci, E | 1 |
| Björklund, A; Carta, M; Garcia, J; Shin, E; Winkler, C | 1 |
| Gupta, A; Kalonia, H; Kumar, A; Mishra, J; Sharma, N | 1 |
| Ahmad, SO; Healy-Stoffel, M; Levant, B; Stanford, JA | 1 |
| Dunnett, SB; Heuer, A | 1 |
| Bargas, J; Boronat-García, A; Drucker-Colín, R; García-Montes, JR; Guerra-Crespo, M; López-Colomé, AM | 1 |
| Lu, C; Roisen, F; Wang, M | 1 |
| Geissler, SA; Lee, HJ; Schallert, T; Smith, ES | 1 |
| Agari, T; Date, I; Kadota, T; Kameda, M; Kikuchi, Y; Liang, H; Shinko, A; Thomas Tayra, J; Vcelar, B; Wakamori, T; Wang, F; Weik, R; Yasuhara, T | 1 |
| Bezard, E; Björklund, A; Carta, M; Li, Q; Pioli, EY; Porras, G; Tronci, E | 1 |
| Huston, JP; Petri, D; Pum, M; Schnitzler, A; Vesper, J | 1 |
| Dunnett, SB; Heuer, A; Klein, A; Lane, EL; Smith, GA; Vinh, NN | 1 |
| Baumgärtner, W; Carroll, C; Effenberg, A; Gibb, R; Grothe, C; Klein, A; Ratzka, A | 1 |
| Dunnett, SB; Klein, A; Lindgren, HS | 1 |
| Björklund, A; Carta, M; Devoto, P; Rogers, JT; Shin, E | 1 |
| Healy-Stoffel, M; Levant, B; Omar Ahmad, S; Stanford, JA | 1 |
| Banerjee, M; Mohanakumar, KP; Nthenge-Ngumbau, DN; Tripathy, D; Verma, P | 1 |
| Drucker-Colín, R; Valle-Leija, P | 1 |
| Boix, J; Padel, T; Paul, G | 1 |
| Collier, TJ; Gebremedhin, KG; O'Malley, J; Paumier, KL; Rademacher, DJ; Sisson, KA; Sortwell, CE; Stancati, JA; Steece-Collier, K | 1 |
| Hauber, W; Mai, B | 1 |
| Carlsson, T; Depboylu, C; Höglinger, GU; Keber, U; Klietz, M; Oertel, WH; Schäfer, MK; Weihe, E | 1 |
| Aranda, IA; Coenen, VA; Döbrössy, MD; Furlanetti, LL | 1 |
| Latagliata, EC; Milia, C; Puglisi-Allegra, S; Saccoccio, P | 1 |
| Atlas, D | 1 |
| Iversen, SD | 1 |
| Davis, B; Filichia, E; Hoffer, B; Luo, Y; Lv, T; Pace, J; Selman, W; Zhou, X | 1 |
| Cao, VY; Elkahloun, AG; Liu, Q; Mastwal, S; Ren, M; Wang, KH; Ye, Y; Zhang, W | 1 |
| Airavaara, M; Bespalov, MM; Fuchs, E; Garea-Rodríguez, E; Heikkinen, H; Kalkkinen, N; Kuure, S; Mätlik, K; Penn, R; Penttinen, AM; Peränen, J; Piccinini, E; Runeberg-Roos, P; Saarma, M | 1 |
| Amalric, M; Beurrier, C; Camon, J; Guiraudie-Capraz, G; Kerkerian-Le Goff, L; Liberge, M; Maurice, N; Ztaou, S | 1 |
| Antkiewicz-Michaluk, L; Czarnecka, A; Kamińska, K; Konieczny, J; Lenda, T | 1 |
| Dunnett, SB; Fjodorova, M; Torres, EM | 1 |
| Chen, SS; Duan, WM; Hao, F; Hao, Q; Hoffer, B; Lu, T; Wang, YY; Xu, QY; Yang, C; Zhao, LR; Zhou, W | 1 |
| Brudek, T; Doudet, DJ; Flores, J; Russ, K | 1 |
| Bjarkam, CR; Christensen, AB; Ettrup, KS; Orlowski, D; Sørensen, JCH | 1 |
| Anderson, KA; Bhupal, PK; Dunbar, GL; Hoolsema, KS; Lynn, JD; Rossignol, J; Sandstrom, MI; Shall, GP | 1 |
| Hänninen, R; Koski, SK; Leino, S; Rannanpää, S; Salminen, O; Tapanainen, T | 1 |
| Gainza, E; Hernandez, RM; Hernando, S; Herran, E; Igartua, M; Lafuente, JV; Morera-Herreras, T; Pedraz, JL; Requejo, C; Ruiz-Ortega, JA; Ugedo, L | 1 |
| Denibaud, AS; Drieu La Rochelle, C; Loiodice, S; Méot, B; Montagne, P; Rion, B; Viel, R; Wing Young, H | 1 |
| Davies, DL; Jakowec, MW; Kang, MS; Warnecke, AMP | 1 |
| Antipova, V; Hawlitschka, A; Holzmann, C; Witt, M; Wree, A | 1 |
| Cunha, JPMCM; Elabi, OF; Fex, M; Gaceb, A; Paul, G | 1 |
| Beynon, AL; Brown, RM; Davies, JS; Dunnett, SB; Lelos, MJ; Morgan, AH; Phelps, L; Rees, D; Roberts, LD; Smith, GA; Wells, T | 1 |
6 review(s) available for amphetamine and oxidopamine
| Article | Year |
|---|---|
Nigral grafts in neonatal rats: protection from aphagia induced by subsequent adult 6-OHDA lesions.
Topics: Age Factors; Amphetamine; Animals; Animals, Newborn; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Feeding Behavior; Fetal Tissue Transplantation; Haloperidol; Hydroxydopamines; Hypothalamus; Mesencephalon; Oxidopamine; Rats; Receptors, Dopamine; Substantia Nigra | 1990 |
[Role of the catecholaminergic system of the brain in addiction to alcohol (review)].
Topics: Acetaldehyde; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcohol Deterrents; Alcoholism; Amphetamine; Animals; Brain; Brain Chemistry; Catecholamines; Cholinergic Fibers; Cricetinae; Dopamine; Ethanol; Humans; Hydroxydopamines; Hypothalamus; Isoquinolines; Levodopa; Mice; Norepinephrine; Oxidopamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Catecholamine; Serotonin; Synaptic Transmission | 1985 |
The role of excitatory amino acids in experimental models of Parkinson's disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Catalepsy; Disease Models, Animal; Excitatory Amino Acids; Levodopa; N-Methylaspartate; Oxidopamine; Parkinson Disease; Rats | 1994 |
Limbic cortical-ventral striatal systems underlying appetitive conditioning.
Topics: Amphetamine; Animals; Appetitive Behavior; Arousal; Avoidance Learning; Columbidae; Conditioning, Classical; Corpus Striatum; Dopamine; Dopamine Antagonists; Female; Goals; Gyrus Cinguli; Humans; Learning; Limbic System; Male; Models, Neurological; Models, Psychological; Motivation; Nerve Net; Neural Pathways; Neurotoxins; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rabbits; Rats; Reward; Time Factors | 2000 |
Convergent functional genomics: application to bipolar disorder.
Topics: Amphetamine; Animals; Bipolar Disorder; Cloning, Molecular; Gene Expression Profiling; Genetic Linkage; Genetics, Behavioral; Humans; Mice; Models, Animal; Oligonucleotide Array Sequence Analysis; Oxidopamine; Rats; Sleep Deprivation; Sympathomimetics | 2001 |
Peter H. Kelly, Paul W. Seviour and Susan D. Iversen (1975) "Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum" [Brain Res. 94 (3) 507-522].
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agents; Locomotion; Nucleus Accumbens; Oxidopamine; Rats; Stereotyped Behavior | 2016 |
325 other study(ies) available for amphetamine and oxidopamine
| Article | Year |
|---|---|
NBQX (6-nitro-sulfamoyl-benzo-quinoxaline-dione) and CPP (3-carboxy-piperazin-propyl phosphonic acid) potentiate dopamine agonist induced rotations in substantia nigra lesioned rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Apomorphine; Dopamine Agents; Drug Synergism; Ibotenic Acid; Lisuride; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1992 |
The effect of intrastriatal application of directly and indirectly acting dopamine agonists and antagonists on the in vivo release of acetylcholine measured by brain microdialysis. The importance of the post-surgery interval.
Topics: Acetylcholine; Amphetamine; Animals; Benzazepines; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Ergolines; Haloperidol; Indoles; Male; Oxidopamine; Phenanthridines; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride | 1992 |
Cryopreservation, survival and function of intrastriatal fetal mesencephalic grafts in a rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Brain Tissue Transplantation; Corpus Striatum; Cryopreservation; Female; Fetal Tissue Transplantation; Graft Survival; Immunohistochemistry; Mesencephalon; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 1992 |
Transplantation of embryonic mesencephalic and medullary raphe neurons to the neostriatum of rats with unilateral 6-hydroxydopamine lesions.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Tissue Transplantation; Corpus Striatum; Fetal Tissue Transplantation; Immunohistochemistry; Medulla Oblongata; Mesencephalon; Neurons; Oxidopamine; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 1992 |
Stimulation of locomotor activity by intra-accumbens AMPA is not inhibited by neonatal 6-hydroxydopamine-induced lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Animals, Newborn; Ibotenic Acid; Injections; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains | 1992 |
Do forebrain structures compete for behavioral expression? Evidence from amphetamine-induced behavior, microdialysis, and caudate-accumbens lesions in medial frontal cortex damaged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Analysis of Variance; Animals; Biogenic Monoamines; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Prosencephalon; Rats; Stereotaxic Techniques; Stereotyped Behavior; Time Factors | 1992 |
Forebrain norepinephrine: role in controlled information processing in the rat.
Topics: Acoustic Stimulation; Amphetamine; Animals; Arousal; Brain Chemistry; Discrimination, Psychological; Male; Mental Processes; Norepinephrine; Oxidopamine; Photic Stimulation; Prosencephalon; Psychomotor Performance; Rats; Space Perception; Sympathectomy, Chemical | 1992 |
The intrastriatal 6-hydroxydopamine model of hemiparkinsonism: quantitative receptor autoradiographic evidence of correlation between circling behavior and presynaptic as well as postsynaptic nigrostriatal markers in the rat.
Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Biomarkers; Corpus Striatum; Immunohistochemistry; Injections; Male; Mazindol; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substantia Nigra; Synapses | 1992 |
Implantation of genetically modified mesencephalic fetal cells into the rat striatum.
Topics: Amphetamine; Animals; Autoradiography; Brain Tissue Transplantation; Cell Line; Corpus Striatum; Female; Fetal Tissue Transplantation; Genetic Vectors; Immunohistochemistry; Mazindol; Mesencephalon; Nucleic Acid Hybridization; Oxidopamine; Parkinson Disease, Secondary; Pregnancy; Protein Kinase C; Rats; Rats, Inbred Strains; Retroviridae; Stereotyped Behavior | 1992 |
Factors in amphetamine-induced contralateral rotation in the unilateral 6-OHDA lesion rat model during the first-week postoperative: implications for neuropathology and neural grafting.
Topics: Amphetamine; Animals; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Male; Models, Neurological; Oxidopamine; Postoperative Period; Rats; Rats, Inbred Strains; Rotation | 1992 |
Serotonergic sprouting in the neostriatum after intrastriatal transplantation of fetal ventral mesencephalon.
Topics: Amphetamine; Animals; Brain; Brain Tissue Transplantation; Corpus Striatum; Female; Fetal Tissue Transplantation; Immunohistochemistry; Mesencephalon; Nerve Regeneration; Oxidopamine; Rats; Rats, Inbred Strains; Rotation; Serotonin; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 1991 |
Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior.
Topics: Amphetamine; Animals; Apomorphine; Axons; Denervation; Disease Models, Animal; Female; Motor Activity; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred Strains; Rotation; Substantia Nigra; Tyrosine 3-Monooxygenase | 1991 |
Chronic levodopa impairs the recovery of dopamine agonist-induced rotational behavior following neural grafting.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Brain Tissue Transplantation; Dopamine; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Fetal Tissue Transplantation; Levodopa; Male; Mesencephalon; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympathectomy, Chemical | 1991 |
Intrastriatal dopaminergic agents, muscarinic stimulation, and GABA antagonism compared for rotation responses in rats.
Topics: Amphetamine; Animals; Apomorphine; Carbachol; Corpus Striatum; Dopamine; Dopamine Agents; GABA Antagonists; Haloperidol; Male; Microinjections; Oxidopamine; Parasympathomimetics; Rats; Rats, Inbred Strains; Rotation; Stereotaxic Techniques; Stereotyped Behavior; Substantia Nigra | 1991 |
Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain Diseases; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Osmolar Concentration; Oxidopamine; Rats; Synaptic Transmission | 1990 |
Decrease of behavioral and biochemical denervation supersensitivity of rat striatum by nigral transplants.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Corpus Striatum; Denervation; Dopamine; Ergolines; Fetal Tissue Transplantation; Homovanillic Acid; Indoles; Mesencephalon; Motor Activity; Oxidopamine; Phenanthridines; Quinpirole; Rats; Receptors, Dopamine; Substantia Nigra | 1991 |
Effects of competitive N-methyl-D-aspartate antagonists on midbrain dopamine neurons: an electrophysiological and behavioral comparison to phencyclidine.
Topics: Amino Acids; Amphetamine; Animals; Behavior, Animal; Dopamine; Electrophysiology; Limbic System; Male; Mesencephalon; Motor Activity; N-Methylaspartate; Neurons; Nucleus Accumbens; Oxidopamine; Phencyclidine; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Regional changes of striatal dopamine receptors following denervation by 6-hydroxydopamine and fetal mesencephalic grafts in the rat.
Topics: Amphetamine; Animals; Benzazepines; Brain Tissue Transplantation; Corpus Striatum; Female; Fetal Tissue Transplantation; Mesencephalon; Oxidopamine; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Stereotyped Behavior; Sympathectomy, Chemical | 1991 |
Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Diseases; Brain Tissue Transplantation; Cocaine; Dopamine; Fetal Tissue Transplantation; Fluoxetine; Imipramine; Male; Neural Pathways; Neurotransmitter Uptake Inhibitors; Nomifensine; Oxidopamine; Piperazines; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
Correlation of functional recovery after a 6-hydroxydopamine lesion with survival of grafted fetal neurons and release of dopamine in the striatum of the rat.
Topics: Amphetamine; Animals; Apomorphine; Cell Survival; Corpus Striatum; Dialysis; Dopamine; Female; Fetal Tissue Transplantation; Histocytochemistry; Hydroxydopamines; Neurons; Neurotoxins; Oxidopamine; Rats; Rotation; Stereotyped Behavior | 1991 |
The effects of 6-OHDA-induced dopamine depletions in the ventral or dorsal striatum on maternal and sexual behavior in the female rat.
Topics: Amphetamine; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Estradiol; Female; Lactation; Maternal Behavior; Motor Activity; Ovariectomy; Oxidopamine; Progesterone; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Substantia Nigra | 1991 |
Similar post-lesion receptor readjustments following the unilateral 6-hydroxydopamine lesion of the dopaminergic mesotelencephalic system in neonatal and adult rats.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Dopamine Agents; Hydroxydopamines; Male; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Rotation; Serotonin; Telencephalon | 1990 |
6-Hydroxydopamine lesions of the olfactory tubercle do not alter (+)-amphetamine-conditioned place preference.
Topics: Amphetamine; Animals; Brain Mapping; Choice Behavior; Conditioning, Classical; Dopamine; Hydroxydopamines; Male; Motor Activity; Norepinephrine; Nucleus Accumbens; Olfactory Bulb; Olfactory Pathways; Orientation; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1990 |
Importance of catecholamine release for the functional action of intrastriatal implants of adrenal medullary cells: pharmacological analysis and in vivo electrochemistry.
Topics: Adrenal Medulla; Amphetamine; Animals; Apomorphine; Catecholamines; Chromaffin System; Corpus Striatum; Denervation; Dopamine; Electrochemistry; Hydroxydopamines; Immunohistochemistry; Male; Motor Activity; Nicotine; Oxidopamine; Pimozide; Rats; Rats, Inbred Strains; Transplantation, Heterotopic | 1990 |
Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis.
Topics: Amphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Drug Synergism; Estradiol; Female; Hydroxydopamines; Motor Activity; Ovary; Oxidopamine; Rats; Rats, Inbred Strains; Rotation | 1990 |
Differential regulation of dopamine metabolism in solid fetal substantia nigra transplants and their terminals in the host striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Feedback; Fetal Tissue Transplantation; Homovanillic Acid; Hydroxydopamines; Male; Nerve Endings; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra | 1990 |
The effect of L-dopa and carbidopa on behavioural recovery produced by ventral mesencephalic grafts in rats.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Tissue Transplantation; Carbidopa; Corpus Striatum; Female; Fetal Tissue Transplantation; Hydroxydopamines; Levodopa; Mesencephalon; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra | 1990 |
Mechanisms of action of adrenal medulla grafts: the possible role of peripheral and central dopamine systems.
Topics: Adrenal Medulla; Adrenalectomy; Amphetamine; Animals; Apomorphine; Blood-Brain Barrier; Cerebral Ventricles; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Hydroxydopamines; Male; Models, Biological; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred Strains; Transplantation, Heterotopic | 1990 |
A functional assessment of embryonic dopaminergic grafts in the marmoset.
Topics: Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Callitrichinae; Corpus Striatum; Disease Models, Animal; Dopamine; Fetal Tissue Transplantation; Functional Laterality; Hydroxydopamines; Mesencephalon; Motor Activity; Motor Skills; Oxidopamine; Parkinson Disease | 1990 |
Effect of dopaminergic denervation and transplant-derived reinnervation on a marker of striatal GABAergic function.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Denervation; Dopamine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hydroxydopamines; Kinetics; Male; Mesencephalon; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains | 1989 |
A 6-hydroxydopamine-induced selective parkinsonian rat model.
Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Disease Models, Animal; Functional Laterality; Hydroxydopamines; Limbic System; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereotyped Behavior | 1989 |
A role for the mesolimbic dopamine system in the psychostimulant actions of MDMA.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Desipramine; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Oxidopamine; Psychotropic Drugs; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Septal Nuclei | 1989 |
Rotational behavior mediated by dopaminergic and nondopaminergic mechanisms after intranigral microinjection of specific mu, delta and kappa opioid agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amphetamine; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hydroxydopamines; Male; Microinjections; Motor Activity; Naloxone; Narcotics; Oxidopamine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rotation | 1988 |
Effects of N-allylnormetazocine (SKF 10,047), phencyclidine, and other psychomotor stimulants in the rat following 6-hydroxydopamine lesion of the ventral tegmental area.
Topics: Amphetamine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Scopolamine; Tegmentum Mesencephali | 1986 |
Functional recovery in a rat model of Parkinson's disease following transplantation of cultured human sympathetic neurons.
Topics: Amphetamine; Animals; Behavior, Animal; Catecholamines; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Fetus; Ganglia, Sympathetic; Humans; Hydroxydopamines; Oxidopamine; Parkinson Disease, Secondary; Substantia Nigra; Tyrosine 3-Monooxygenase | 1986 |
Study on the mechanism of the long-lasting antagonistic effect of caerulein on amphetamine-induced hyperactivity in rats.
Topics: Amphetamine; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Ceruletide; Endorphins; Haloperidol; Hydroxydopamines; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sodium Glutamate | 1986 |
Endogenous dopamine functionally activates D-1 and D-2 receptors in striatum.
Topics: Amphetamine; Animals; Corpus Striatum; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride | 1987 |
Blockade of amphetamine but not opiate-induced locomotion following antagonism of dopamine function in the rat.
Topics: Amphetamine; Animals; Dopamine Antagonists; Flupenthixol; Heroin; Hydroxydopamines; Limbic System; Male; Motor Activity; Narcotic Antagonists; Oxidopamine; Rats; Rats, Inbred Strains | 1986 |
Investigation of the failure of parenterally administered haloperidol to antagonize dopamine released from micropipettes in the caudate.
Topics: Amphetamine; Animals; Apomorphine; Caudate Nucleus; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Hydroxydopamines; Infusions, Parenteral; Male; Oxidopamine; Phencyclidine; Rats; Rats, Inbred Strains; Time Factors | 1986 |
The rotating 6-hydroxydopamine-lesioned mouse as a model for assessing functional effects of neuronal grafting.
Topics: Amphetamine; Animals; Basal Ganglia Diseases; Corpus Striatum; Disease Models, Animal; Dopamine; Hydroxydopamines; Mesencephalon; Mice; Movement Disorders; Oxidopamine | 1986 |
Effect of glucose on amphetamine-induced motor behavior.
Topics: Amphetamine; Animals; Corpus Striatum; Dose-Response Relationship, Drug; Glucose; Hydroxydopamines; Male; Motor Activity; Neurons; Oxidopamine; Rats; Receptors, Dopamine; Stereotyped Behavior; Substantia Nigra | 1986 |
Simultaneous measurement of dopamine release and rotational behaviour in 6-hydroxydopamine denervated rats using intracerebral dialysis.
Topics: Amphetamine; Animals; Behavior, Animal; Brain; Corpus Striatum; Denervation; Dialysis; Dopamine; Extracellular Space; Hydroxydopamines; Levodopa; Male; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values | 1986 |
Transient contralateral rotation following unilateral substantia nigra lesion reflects susceptibility of the nigrostriatal system to exhaustion by amphetamine.
Topics: Amphetamine; Animals; Corpus Striatum; Desipramine; Dominance, Cerebral; Drug Tolerance; Hydroxydopamines; Male; Motor Activity; Movement Disorders; Oxidopamine; Rats; Rats, Inbred Strains; Rotation; Stress, Physiological; Substantia Nigra | 1986 |
Ethanol induces rotational behavior in 6-hydroxydopamine lesioned mice.
Topics: Amphetamine; Animals; Apomorphine; Ethanol; Hydroxydopamines; Male; Mice; Oxidopamine; Receptors, Dopamine; Stereotyped Behavior | 1987 |
Effect of permanently charged and uncharged dopaminergic agonists on the potassium-induced release of [3H]acetylcholine from striatal slices.
Topics: Acetylcholine; Amphetamine; Animals; Atropine; Corpus Striatum; Dopamine; Electrochemistry; Hydroxydopamines; Male; Mice; Oxidopamine; Potassium; Quaternary Ammonium Compounds; Receptors, Dopamine; Sulfides; Sulfones; Sulfonium Compounds; Sulfoxides | 1987 |
Nucleus accumbens opiate-dopamine interactions and locomotor activation in the rat: evidence for a pre-synaptic locus.
Topics: Amphetamine; Animals; Apomorphine; Dopamine; Hydroxydopamines; Male; Motor Activity; Naloxone; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Septal Nuclei; Synapses | 1987 |
Method for stimulating the adrenergic system of an isolated perfused rat heart.
Topics: Amphetamine; Animals; Bretylium Compounds; Electric Stimulation; Heart; Heart Rate; Hydroxydopamines; In Vitro Techniques; Male; Norepinephrine; Oxidopamine; Propranolol; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1987 |
Lesions of dopamine neurons in the medial prefrontal cortex: effects on self-administration of amphetamine and dopamine synthesis in the brain of the rat.
Topics: Amphetamine; Animals; Brain; Dopamine; Frontal Lobe; Hydroxydopamines; Male; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Self Administration | 1987 |
Circling behaviour in rats with unilateral lesions of the nigrostriatum induced by 6-hydroxydopamine: changes induced by oral administration of cytidine-5'-diphosphocholine.
Topics: Administration, Oral; Amphetamine; Animals; Apomorphine; Behavior, Animal; Choline; Corpus Striatum; Cytidine Diphosphate Choline; Hydroxydopamines; Levodopa; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1987 |
Increased sensitivity to amphetamine and facilitation of amphetamine self-administration after 6-hydroxydopamine lesions of the amygdala.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amygdala; Animals; Cardiac Catheterization; Dextroamphetamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Motor Activity; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Self Administration; Sympathectomy, Chemical | 1988 |
Vestibulo-ocular reflex adaptation in cats before and after depletion of norepinephrine.
Topics: Adaptation, Physiological; Amphetamine; Animals; Arousal; Attention; Brain; Cats; Dopamine; Female; Hydroxydopamines; Norepinephrine; Oxidopamine; Reflex, Vestibulo-Ocular; Saccades | 1988 |
Apomorphine induces latent rotation in lesioned rats, amphetamine does not.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1988 |
Comparison between apomorphine and amphetamine-induced rotational behaviour in rats with a unilateral nigrostriatal pathway lesion.
Topics: Amphetamine; Animals; Apomorphine; Brain; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1988 |
Intrastriatal dopaminergic grafts restore inhibitory control over striatal cholinergic neurons.
Topics: Acetylcholine; Amphetamine; Animals; Choline; Cholinergic Fibers; Corpus Striatum; Dopamine; Electric Stimulation; Hydroxydopamines; Male; Mesencephalon; Neural Inhibition; Oxidopamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra | 1988 |
Release of acetylcholine and its dopaminergic control in slices from striatal grafts in the ibotenic acid-lesioned rat striatum.
Topics: Acetylcholine; Amphetamine; Animals; Corpus Striatum; Dopamine; Ergolines; Hydroxydopamines; Ibotenic Acid; In Vitro Techniques; Nomifensine; Oxazoles; Oxidopamine; Quinpirole; Rats; Rats, Inbred Strains; Sulpiride; Transplantation, Homologous | 1988 |
Differential effects of dopamine D-1 and D-2 agonists and antagonists in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Benzazepines; Brain; Ergolines; Humans; Hydroxydopamines; Oxidopamine; Pergolide; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior | 1985 |
Evidence that [3H]dopamine is taken up and released from nondopaminergic nerve terminals in the rat substantia nigra in vitro.
Topics: Amphetamine; Animals; Catecholamines; Corpus Striatum; Desipramine; Dopamine; Female; Fluoxetine; Hydroxydopamines; Medial Forebrain Bundle; Nerve Endings; Nomifensine; Oxidopamine; Potassium Chloride; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra; Synaptosomes | 1985 |
Norepinephrine-dependent and independent mechanisms of persistent effects of amphetamine in rat cerebellum.
Topics: Amphetamine; Animals; Cerebellum; Electric Stimulation; Hydroxydopamines; Methoxyhydroxyphenylglycol; Norepinephrine; Oxidopamine; Propranolol; Purkinje Cells; Rats; Rats, Inbred Strains | 1985 |
The role of noradrenaline in tuning and dopamine in switching between signals in the CNS.
Topics: Adrenergic Fibers; Amphetamine; Animals; Arousal; Attention; Brain; Corpus Striatum; Dopamine; Electric Stimulation; Humans; Hydroxydopamines; Learning; Limbic System; Memory; Motivation; Neural Pathways; Norepinephrine; Oxidopamine; Psychophysiology; Rats; Substantia Nigra | 1985 |
Dopaminergic denervation increases [3H](+)-amphetamine binding in the rat striatum.
Topics: Amphetamine; Animals; Corpus Striatum; Denervation; Hydroxydopamines; In Vitro Techniques; Oxidopamine; Rats; Receptors, Dopamine; Tritium | 1985 |
Trace amines inhibit the electrically evoked release of [3H]acetylcholine from slices of rat striatum in the presence of pargyline: similarities between beta-phenylethylamine and amphetamine.
Topics: Acetylcholine; alpha-Methyltyrosine; Amphetamine; Animals; Corpus Striatum; Dopamine; Drug Interactions; Electric Stimulation; Evoked Potentials; Hydroxydopamines; Male; Methyltyrosines; Monoamine Oxidase Inhibitors; Octopamine; Oxidopamine; Pargyline; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Tyramine | 1985 |
Activation of striatal dopaminergic grafts by haloperidol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Corpus Striatum; Denervation; Dopamine; Female; Haloperidol; Hydroxydopamines; Motor Activity; Nerve Regeneration; Oxidopamine; Rats; Rats, Inbred Strains | 1985 |
Effects of serotonergic activity in nucleus accumbens septi on drug-induced circling.
Topics: 5,7-Dihydroxytryptamine; Amphetamine; Animals; Apomorphine; Hydroxydopamines; Injections, Intraventricular; Male; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Septal Nuclei; Serotonin; Stereotyped Behavior | 1985 |
Apomorphine-induced inhibition of neostriatal activity is enhanced by lesions induced by 6-hydroxydopamine but not by long-term administration of amphetamine.
Topics: Action Potentials; Amphetamine; Animals; Apomorphine; Caudate Nucleus; Hydroxydopamines; Male; Neurons; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Neurotransmitter | 1984 |
Assessing pharmacologically induced dopamine receptor sensitivity changes with the Ungerstedt turning model.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Haloperidol; Hydroxydopamines; Male; Models, Biological; Oxidopamine; Rats; Receptors, Dopamine; Rotation | 1981 |
The effects of prolyl-leucyl-glycine amide on drug-induced rotation in lesioned rats.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Motor Activity; MSH Release-Inhibiting Hormone; Oxidopamine; Rats; Rats, Inbred Strains; Rotation; Stereotaxic Techniques; Substantia Nigra | 1982 |
Neuroleptic inhibition of 6,7-ADTN-induced hyperactivity after injection into the nucleus accumbens. Specificity and comparison with other models.
Topics: Amphetamine; Animals; Antipsychotic Agents; Humans; Hydroxydopamines; Injections; Male; Motor Activity; Naphthalenes; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Tetrahydronaphthalenes | 1983 |
Blockade of MK-801 induced ipsiversive turning in 6-OHDA lesioned rats by alpha 1-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Anticonvulsants; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Butyrophenones; Dibenzazepines; Dibenzocycloheptenes; Dizocilpine Maleate; Female; Humans; Hydroxydopamines; Oxidopamine; Postural Balance; Prazosin; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra | 1984 |
Differential inhibition by dopamine D-1 and D-2 antagonists of circling behaviour induced by dopamine agonists in rats with unilateral 6-hydroxydopamine lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Antipsychotic Agents; Appetite Depressants; Benzamides; Benzazepines; Catalepsy; Clopenthixol; Ergolines; Flupenthixol; Humans; Hydroxydopamines; Male; Oxidopamine; Pergolide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior | 1984 |
Spontaneous recovery from motor asymmetry in adult rats with 6-hydroxydopamine-induced partial lesions of the substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Dopamine; Female; Functional Laterality; Homovanillic Acid; Hydroxydopamines; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra; Tyrosine 3-Monooxygenase | 1984 |
The citalopram/5-HTP-induced head shake syndrome is correlated to 5-HT2 receptor affinity and also influenced by other transmitters.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Binding, Competitive; Brain; Citalopram; Female; Guinea Pigs; Histamine Antagonists; Humans; Hydroxydopamines; In Vitro Techniques; Male; Neurotransmitter Agents; Oxidopamine; Prazosin; Propylamines; Propylbenzilylcholine Mustard; Rats; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Muscarinic; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Stereotyped Behavior | 1984 |
Retrograde transport of dopamine beta-hydroxylase antibodies in sympathetic neurons: effects of drugs modifying noradrenergic transmission.
Topics: Amphetamine; Animals; Antibodies; Axonal Transport; Dopamine beta-Hydroxylase; Ganglia, Sympathetic; Guinea Pigs; Hydroxydopamines; Iris; Microscopy, Fluorescence; Neurons; Norepinephrine; Oxidopamine; Phentolamine; Phenylephrine; Synaptic Transmission | 1984 |
Evidence for a role of endogenous opioids in the nigrostriatal system: influence of naloxone and morphine on nigrostriatal dopaminergic supersensitivity.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Endorphins; Humans; Hydroxydopamines; Male; Morphine; Naloxone; Oxidopamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1983 |
An automated method for measurement of circling behavior in the mouse.
Topics: Amphetamine; Animals; Autoanalysis; Computers; Humans; Hydroxydopamines; Male; Methods; Mice; Motor Activity; Oxidopamine; Rotation; Stereotyped Behavior | 1983 |
Reduction of 3H-spiroperidol binding in rat striatum and frontal cortex by chronic amphetamine: dose response, time course and role of sustained dopamine release.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Binding, Competitive; Butyrophenones; Cerebral Cortex; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Methyltyrosines; Oxidopamine; Rats; Rats, Inbred Strains; Spiperone; Time Factors | 1983 |
Dissociable effects of 6-OHDA-induced lesions of neostriatum on anorexia, locomotor activity and stereotypy: the role of behavioural competition.
Topics: Amphetamine; Animals; Anorexia; Catecholamines; Corpus Striatum; Feeding and Eating Disorders; Feeding Behavior; Humans; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Rats; Stereotyped Behavior | 1984 |
Repeated stress increases locomotor response to amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Amphetamine; Amygdala; Animals; Apomorphine; Cerebral Cortex; Dopamine; Humans; Hydroxydopamines; Limbic System; Male; Methyltyrosines; Motor Activity; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Stress, Psychological | 1984 |
Drug-induced circling after unilateral 6-hydroxydopamine lesions of the nigro-striatal pathway is mediated via the midbrain periaqueductal grey and adjacent reticular formation (angular complex).
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Electrolysis; Female; Hydroxydopamines; Kainic Acid; Medial Forebrain Bundle; Mesencephalon; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1981 |
Functional validation of projection topography in the nigrostriatal dopamine system.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Apomorphine; Caudate Nucleus; Corpus Striatum; Dopamine; Female; Humans; Hydroxydopamines; Mesencephalon; Methyltyrosines; Motor Activity; Oxidopamine; Rats; Rotation; Substantia Nigra | 1982 |
Behavioural effects of electrolytic and 6-hydroxydopamine lesions of the accumbens and caudate-putamen nuclei.
Topics: Amphetamine; Animals; Behavior, Animal; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Norepinephrine; Nucleus Accumbens; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; Septal Nuclei; Serotonin | 1982 |
The importance of calcium in the amphetamine-induced stimulation of dopamine synthesis in mouse striata in vivo.
Topics: Amphetamine; Animals; Calcium; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Egtazic Acid; Hydroxydopamines; Kinetics; Mice; Motor Activity; Oxidopamine; Rotation; Tyrosine | 1982 |
In vivo voltammetry with electrodes that discriminate between dopamine and ascorbate.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Ascorbic Acid; Brain; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Dominance, Cerebral; Dopamine; Electrochemistry; Hydroxydopamines; Male; Oxidopamine; Potassium; Rats; Rats, Inbred Strains | 1982 |
Prostaglandin inhibition of amphetamine-induced circling in mice.
Topics: Amphetamine; Animals; Body Temperature; Corpus Striatum; Humans; Hydroxydopamines; Injections; Injections, Intraventricular; Male; Mice; Oxidopamine; Prostaglandins; Stereotyped Behavior | 1982 |
Priming of a D1 dopamine receptor behavioural response is dissociated from striatal immediate-early gene activity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Apomorphine; Base Sequence; Behavior, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Ergolines; Genes, Immediate-Early; Immunohistochemistry; Male; Molecular Sequence Data; Neostriatum; Neural Pathways; Oxidopamine; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Rotation; Substantia Nigra | 1995 |
Mesencephalic grafts partially restore normal nigral dynorphin levels in 6-hydroxydopamine-lesioned rats treated chronically with L-dihydroxyphenylalanine.
Topics: Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Dihydroxyphenylalanine; Dopamine Agents; Dopamine Agonists; Dynorphins; Female; Fetal Tissue Transplantation; Image Processing, Computer-Assisted; Levodopa; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 1995 |
Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. I. Evidence for anatomical reconstruction of the nigrostriatal pathway.
Topics: Amphetamine; Animals; Animals, Newborn; Axonal Transport; Brain Tissue Transplantation; Cerebral Ventricles; Dopamine; Female; Fetal Tissue Transplantation; Functional Laterality; Genes, fos; Immunohistochemistry; Injections, Intraventricular; Male; Mesencephalon; Neurons; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 1995 |
Graft-induced reduction in [3H]dopamine uptake into the non-lesioned striatum.
Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Dopamine; Fetal Tissue Transplantation; Male; Mesencephalon; Motor Activity; Oxidopamine; Rats; Rats, Wistar; Rotation; Synaptosomes; Tritium | 1995 |
In vivo detection of immunoreactive neurokinin A release within rat substantia nigra and its dependency on a dopaminergic input.
Topics: Amphetamine; Animals; Antibodies; Dopamine; Immunohistochemistry; In Vitro Techniques; Kinetics; Male; Neurokinin A; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra | 1995 |
Behavioral indices of moderate nigro-striatal 6-hydroxydopamine lesion: a preclinical Parkinson's model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Locomotion; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Serotonin; Substantia Nigra | 1993 |
Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. II. Transplant-induced behavioral recovery.
Topics: Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Cerebral Ventricles; Dopamine; Female; Fetal Tissue Transplantation; Forelimb; Functional Laterality; Injections, Intraventricular; Male; Mesencephalon; Motor Activity; Orientation; Oxidopamine; Proto-Oncogene Proteins c-fos; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Rotation; Stress, Physiological; Substantia Nigra; Tyrosine 3-Monooxygenase | 1995 |
Circulating adrenal hormones are not necessary for the development of sensitization to the psychomotor activating effects of amphetamine.
Topics: Adrenal Glands; Amphetamine; Animals; Behavior, Animal; Corticosterone; Exploratory Behavior; Homing Behavior; Male; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley | 1995 |
Influence of novel versus home environments on sensitization to the psychomotor stimulant effects of cocaine and amphetamine.
Topics: Amphetamine; Animals; Apomorphine; Cocaine; Environment; Male; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation; Stimulation, Chemical | 1995 |
The increase in striatal neuropeptide Y immunoreactivity induced by neonatal dopamine-depleting lesions in rats is reversed by intrastriatal dopamine-rich transplants.
Topics: Amphetamine; Animals; Animals, Newborn; Brain Tissue Transplantation; Denervation; Dopamine; Fetal Tissue Transplantation; Immunohistochemistry; Male; Mesencephalon; Neostriatum; Neural Pathways; Neurons; Neuropeptide Y; Oxidopamine; Rats; Rats, Wistar; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 1994 |
Fluoxetine at anorectic doses does not have properties of a dopamine uptake inhibitor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Appetite Depressants; Brain Chemistry; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Homovanillic Acid; Injections, Intraventricular; Male; Mazindol; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley | 1994 |
Degeneration of nigrostriatal dopaminergic neurons increases iron within the substantia nigra: a histochemical and neurochemical study.
Topics: Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Histocytochemistry; Iron; Male; Medial Forebrain Bundle; Nerve Degeneration; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra | 1994 |
Dopamine depletion attenuates amphetamine-induced increases of cortical acetylcholine release.
Topics: Acetylcholine; Amphetamine; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Dopamine; Frontal Lobe; Hippocampus; Male; Microdialysis; Neurons; Norepinephrine; Oxidopamine; Parietal Lobe; Prosencephalon; Rats; Rats, Wistar; Serotonin | 1994 |
Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Female; Ibotenic Acid; Motor Activity; Neurons; Oxidopamine; Parvalbumins; Rats; Rats, Sprague-Dawley; Reference Values; Regression Analysis; Rotation; Substantia Nigra; Time Factors | 1994 |
Motor fluctuations in levodopa treated parkinsonian rats: relation to lesion extent and treatment duration.
Topics: Amphetamine; Animals; Apomorphine; Denervation; Immunohistochemistry; Levodopa; Male; Medial Forebrain Bundle; Movement; Neostriatum; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Tyrosine 3-Monooxygenase | 1994 |
Accumbens microinjection of LY 171555 and sulpiride: effects on circling behaviour, in the rat.
Topics: Amphetamine; Animals; Dopamine Agonists; Dopamine Antagonists; Ergolines; Male; Microinjections; Nucleus Accumbens; Oxidopamine; Quinpirole; Rats; Rats, Wistar; Stereotyped Behavior; Sulpiride; Sympathectomy, Chemical | 1994 |
Transection of corticostriatal afferents abolishes the hyperexpression of Fos and counteracts the development of rotational overcompensation induced by intrastriatal dopamine-rich grafts when challenged with amphetamine.
Topics: Afferent Pathways; Amphetamine; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Efferent Pathways; Female; Fetal Tissue Transplantation; Neurons; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra | 1994 |
Intrastriatal implantation of interleukin-1. Reduction of parkinsonism in rats by enhancing neuronal sprouting from residual dopaminergic neurons in the ventral tegmental area of the midbrain.
Topics: Amphetamine; Animals; Behavior, Animal; Dopamine; Drug Implants; Interleukin-1; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tegmentum Mesencephali; Tyrosine 3-Monooxygenase | 1994 |
Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson model.
Topics: Amphetamine; Animals; Brain Tissue Transplantation; Cell Transplantation; Dopamine; Female; Fetal Tissue Transplantation; Graft Survival; Neostriatum; Norepinephrine; Oxidopamine; Parkinson Disease, Secondary; Pregnancy; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra; Tyrosine 3-Monooxygenase | 1994 |
Effect of bilateral 6-OHDA lesions of the substantia nigra on locomotor activity in the rat.
Topics: Amphetamine; Animals; Apomorphine; Body Weight; Immunohistochemistry; Levodopa; Male; Motor Activity; Nerve Fibers; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred F344; Substantia Nigra; Tyrosine 3-Monooxygenase | 1994 |
Enhanced efficacy of nigral-striatal cotransplants in bilaterally dopamine-depleted rats: an anatomical and behavioral analysis.
Topics: Amphetamine; Animals; Corpus Striatum; Dopamine; Fetal Tissue Transplantation; Movement; Neurons; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Stress, Physiological; Substantia Nigra; Tyrosine 3-Monooxygenase | 1994 |
A 6-hydroxydopamine-induced selective parkinsonian rat model: further biochemical and behavioral characterization.
Topics: Amphetamine; Animals; Brain; Carbidopa; Caudate Nucleus; Corpus Striatum; Dopamine; Drug Combinations; Functional Laterality; Immunohistochemistry; Levodopa; Male; Mesencephalon; Models, Neurological; Motor Activity; Nucleus Accumbens; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotation; Tyrosine 3-Monooxygenase | 1994 |
Fetal mesencephalic grafts influence the dopamine release in the non-lesioned striatum of 6-OHDA-lesioned rats: a behavioral and in vivo voltammetric study.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Tissue Transplantation; Dopamine; Electrophysiology; Female; Fetal Tissue Transplantation; Male; Mesencephalon; Neostriatum; Oxidopamine; Pargyline; Pregnancy; Rats; Rats, Wistar | 1994 |
Functional effects of transplanted human fetal ventral mesencephalic brain tissue from spontaneous abortions into a rodent model of Parkinson's disease.
Topics: Abortion, Spontaneous; Amphetamine; Animals; Biomarkers; Brain Tissue Transplantation; Female; Fetal Tissue Transplantation; Gestational Age; Glial Fibrillary Acidic Protein; Humans; Mesencephalon; Motor Activity; NADPH Dehydrogenase; Neurofilament Proteins; Oxidopamine; Parkinson Disease, Secondary; Pregnancy; Rats; Rotation; Transplantation, Heterologous; Tyrosine 3-Monooxygenase | 1994 |
Relationship between asymmetries in striatal dopamine release and the direction of amphetamine-induced rotation during the first week following a unilateral 6-OHDA lesion of the substantia nigra.
Topics: Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Female; Microdialysis; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Substantia Nigra; Time Factors | 1994 |
Conditioning versus priming of dopaminergic grafts by amphetamine.
Topics: Amphetamine; Animals; Brain; Brain Tissue Transplantation; Conditioning, Psychological; Dopamine; Female; Fetal Tissue Transplantation; Histocytochemistry; Mesencephalon; Oxidopamine; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Rotation; Tyrosine 3-Monooxygenase | 1993 |
Midbrain 6-hydroxydopamine lesions modulate blink reflex excitability.
Topics: Amphetamine; Animals; Basal Ganglia; Blinking; Electric Stimulation; Electromyography; Habituation, Psychophysiologic; Immunohistochemistry; Mesencephalon; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Substantia Nigra; Trigeminal Nerve; Tyrosine 3-Monooxygenase | 1993 |
Adrenal medulla grafts in the hemiparkinsonian rat: profile of behavioral recovery predicts restoration of the symmetry between the two striata in measures of pre- and postsynaptic dopamine function.
Topics: Adrenal Medulla; Amphetamine; Animals; Apomorphine; Benzazepines; Cerebral Ventricles; Corpus Striatum; Denervation; Female; Functional Laterality; In Situ Hybridization; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Receptors, Dopamine D2; RNA, Messenger; Rotation; Spiperone; Substantia Nigra; Transplantation, Heterotopic; Tyrosine 3-Monooxygenase | 1993 |
Effects of ventral striatal 6-OHDA lesions or amphetamine sensitization on ethanol consumption in the rat.
Topics: Alcohol Drinking; Amphetamine; Animals; Dopamine; Female; Motor Activity; Neostriatum; Norepinephrine; Oxidopamine; Rats; Rats, Wistar; Serotonin; Stereotyped Behavior; Synaptic Transmission | 1994 |
Locomotor activation induced by MK-801 in the rat: postsynaptic interactions with dopamine receptors in the ventral striatum.
Topics: Amphetamine; Animals; Brain; Brain Diseases; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Drug Interactions; Haloperidol; Male; Microinjections; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Synapses | 1994 |
Asymmetrical orientation to edges of an openfield: modulation by striatal dopamine and relationship to motor asymmetries in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Dopamine; Exploratory Behavior; Functional Laterality; Male; Motor Activity; Neostriatum; Orientation; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior | 1994 |
Intranigral injections of SCH 23390 inhibit amphetamine-induced rotational behavior.
Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Benzazepines; Corpus Striatum; Dose-Response Relationship, Drug; Male; Microinjections; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation; Stereotaxic Techniques; Substantia Nigra; Sulpiride; Time Factors | 1993 |
Transection of corticostriatal afferents reduces amphetamine- and apomorphine-induced striatal Fos expression and turning behaviour in unilaterally 6-hydroxydopamine-lesioned rats.
Topics: Afferent Pathways; Amphetamine; Animals; Apomorphine; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Denervation; Female; Frontal Lobe; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 1993 |
Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Ventral Tegmental Area | 1993 |
Xenogeneic dopaminergic grafts reverse behavioral deficits induced by 6-OHDA in rodents: effect of 15-deoxyspergualin treatment.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Tissue Transplantation; Cerebral Ventricles; Dopamine; Female; Fetal Tissue Transplantation; Guanidines; Immunohistochemistry; Immunosuppressive Agents; Male; Mice; Mice, Inbred C3H; Neurons; Oxidopamine; Pregnancy; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Transplantation, Heterologous | 1993 |
Dopaminergic grafts implanted into the neonatal or adult striatum: comparative effects on rotation and paw reaching deficits induced by subsequent unilateral nigrostriatal lesions in adulthood.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Brain Tissue Transplantation; Corpus Striatum; Denervation; Dopamine; Fetal Tissue Transplantation; Immunohistochemistry; Mesencephalon; Neural Pathways; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Substantia Nigra; Telencephalon | 1993 |
Dopamine-rich grafts in the neostriatum and/or nucleus accumbens: effects on drug-induced behaviours and skilled paw-reaching.
Topics: Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Dopamine; Female; Fetal Tissue Transplantation; Immunohistochemistry; Mesencephalon; Motor Activity; Neostriatum; Nucleus Accumbens; Oxidopamine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympathectomy, Chemical | 1993 |
Role of the corpus callosum in expression of behavioral asymmetries induced by a unilateral dopamine lesion of the substantia nigra in the rat.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Competitive Behavior; Corpus Callosum; Dopamine; Escape Reaction; Exploratory Behavior; Functional Laterality; Male; Oxidopamine; Rats; Stereotyped Behavior; Substantia Nigra | 1993 |
Functional and anatomical reconstruction of the 6-hydroxydopamine lesioned nigrostriatal system of the adult rat.
Topics: Amphetamine; Animals; Axons; Behavior, Animal; Brain Tissue Transplantation; Cell Line; Corpus Striatum; Dopamine; Efferent Pathways; Female; Fetal Tissue Transplantation; Fluorescent Dyes; Mesencephalon; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Rotation; Schwann Cells; Stilbamidines; Substantia Nigra; Tyrosine 3-Monooxygenase | 1996 |
Administration of amphetamine does not increase the functional efficacy of dopaminergic grafts made in infancy.
Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Brain Tissue Transplantation; Conditioning, Psychological; Dopamine; Fetal Tissue Transplantation; Male; Mesencephalon; Motor Activity; Neostriatum; Neurons; Oxidopamine; Pain; Rats; Rats, Wistar; Telencephalon | 1996 |
Time course of striatal changes induced by 6-hydroxydopamine lesion of the nigrostriatal pathway, as studied by combined evaluation of rotational behaviour and striatal Fos expression.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Female; Immunohistochemistry; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 1996 |
Intrastriatal injection of GDNF attenuates the effects of 6-hydroxydopamine.
Topics: Amphetamine; Animals; Apomorphine; Dopamine Agents; Dopamine Agonists; Female; Glial Cell Line-Derived Neurotrophic Factor; Immunohistochemistry; Injections; Neostriatum; Nerve Growth Factors; Nerve Tissue Proteins; Oxidopamine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympatholytics | 1996 |
Foetal nigral cell suspension grafts influence dopamine release in the non-grafted side in the 6-hydroxydopamine rat model of Parkinson's disease: in vivo voltammetric data.
Topics: Amphetamine; Animals; Brain Tissue Transplantation; Disease Models, Animal; Dopamine; Female; Oxidopamine; Parkinson Disease; Putamen; Rats; Rats, Sprague-Dawley | 1996 |
Foetal ventral mesencephalic cell suspension grafts to the 6-hydroxydopamine-lesioned rat reduce the rate of dopamine uptake in the contralateral striatum.
Topics: Amphetamine; Animals; Cell Transplantation; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Female; Fetal Tissue Transplantation; Functional Laterality; Kinetics; Mesencephalon; Microelectrodes; Neostriatum; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley | 1996 |
Effects of amphetamine and 6-hydroxydopamine lesions on reserpine-induced oral dyskinesia.
Topics: Adrenergic Agents; Amphetamine; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Male; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Reserpine; Stereotyped Behavior; Substantia Nigra | 1996 |
Changes in behavior and monoamine levels in microdialysate from dorsal striatum after 6-OHDA infusions into ventral striatum.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Behavior, Animal; Biogenic Monoamines; Dopamine; Dopamine Uptake Inhibitors; Injections; Male; Microdialysis; Motor Activity; Neostriatum; Oxidopamine; Potassium; Rats; Stereotyped Behavior; Sympatholytics | 1996 |
Neuroprotective effects of riluzole on a model of Parkinson's disease in the rat.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Apomorphine; Brain Chemistry; Central Nervous System Stimulants; Conditioning, Operant; Dopamine Agonists; Female; Male; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Riluzole; Stereotyped Behavior; Substantia Nigra; Sympatholytics; Thiazoles | 1996 |
Short-term GDNF treatment provides long-term rescue of lesioned nigral dopaminergic neurons in a rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Antibody Specificity; Behavior, Animal; Cell Death; Disease Models, Animal; Dopamine; Dopamine Agents; Female; Glial Cell Line-Derived Neurotrophic Factor; Motor Activity; Movement; Neostriatum; Nerve Growth Factors; Nerve Regeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Postural Balance; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 1996 |
Reconstruction of the nigrostriatal pathway by simultaneous intrastriatal and intranigral dopaminergic transplants.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Tissue Transplantation; Dopamine; Dopamine Agents; Female; Fetal Tissue Transplantation; Fluorescent Dyes; Neostriatum; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotation; Stilbamidines; Substantia Nigra; Tyrosine 3-Monooxygenase | 1996 |
Rotational behaviour and neurochemical changes in unilateral N-methyl-norsalsolinol and 6-hydroxydopamine lesioned rats.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Catecholamines; Corpus Striatum; Female; Isoquinolines; Monoamine Oxidase; Oxidopamine; Rats; Rats, Wistar; Rotation; Stereoisomerism; Stereotyped Behavior; Substantia Nigra; Tetrahydroisoquinolines | 1996 |
Effects of dopamine depletion in the medial prefrontal cortex on the stress-induced increase in extracellular dopamine in the nucleus accumbens core and shell.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Agents; Fluorescent Dyes; Locomotion; Male; Microdialysis; Neurons; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia; Stilbamidines; Stress, Physiological; Sympatholytics | 1997 |
Drug-free evaluation of rat models of parkinsonism and nigral grafts using a new automated rotarod test.
Topics: Amphetamine; Animals; Apomorphine; Automation; Brain Tissue Transplantation; Female; Fetal Tissue Transplantation; Mesencephalon; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Prosencephalon; Rats; Rats, Sprague-Dawley; Reference Values; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 1997 |
Co-transplantation of fetal lateral ganglionic eminence and ventral mesencephalon can augment function and development of intrastriatal transplants.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Tissue Transplantation; Cell Count; Cell Survival; Corpus Striatum; Denervation; Dopamine; Female; Fetal Tissue Transplantation; Male; Mesencephalon; Neural Pathways; Neurons; Oxidopamine; Pregnancy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Sympatholytics; Sympathomimetics | 1997 |
Enduring enhancement of amphetamine sensitization by drug-associated environmental stimuli.
Topics: Amphetamine; Animals; Corpus Striatum; Dose-Response Relationship, Drug; Male; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley | 1997 |
Effect of morphine on rotational behavior of unilaterally brain-lesioned mice and rats: morphine withdrawal and development of tolerance.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Drug Tolerance; Functional Laterality; Male; Mice; Morphine; Narcotics; Oxidopamine; Rats; Rats, Wistar; Rotation; Substance Withdrawal Syndrome | 1997 |
Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Astrocytes; Brain Tissue Transplantation; Cell Count; Cell Differentiation; Cell Movement; Cell Survival; Cells, Cultured; Corpus Striatum; Dopamine; Epidermal Growth Factor; Fetal Tissue Transplantation; Fibroblast Growth Factor 2; Glial Fibrillary Acidic Protein; Graft Survival; Humans; Motor Activity; Nerve Tissue Proteins; Neurons; Oligodendroglia; Oxidopamine; Parkinson Disease, Secondary; Rats; Recombinant Fusion Proteins; Stem Cell Transplantation; Stem Cells; Tyrosine 3-Monooxygenase | 1997 |
Rat intrastriatal neural allografts challenged with skin allografts at different time points.
Topics: Amphetamine; Animals; Astrocytes; Brain Tissue Transplantation; Cell Count; Corpus Striatum; Female; Fetal Tissue Transplantation; Glial Fibrillary Acidic Protein; Graft Rejection; Histocompatibility Antigens; Immunization; Locomotion; Mesencephalon; Nerve Tissue Proteins; Neurons; Oxidopamine; Postoperative Period; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Skin Transplantation; Transplantation, Homologous; Tyrosine 3-Monooxygenase | 1997 |
Fixed-ratio discrimination training as replacement therapy in Parkinson's disease: studies in a 6-hydroxydopamine-treated rat model.
Topics: Amphetamine; Animals; Apomorphine; Conditioning, Operant; Corpus Striatum; Discrimination Learning; Disease Models, Animal; Dopamine; Dopamine Agents; Male; Motor Activity; Neurotoxins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Reinforcement Schedule | 1998 |
Cellular and functional recovery of Parkinsonian rats after intrastriatal transplantation of carotid body cell aggregates.
Topics: Amphetamine; Animals; Behavior, Animal; Carotid Body; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Graft Survival; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Sympatholytics; Vibrissae | 1998 |
Dopamine depletion in nucleus accumbens influences locomotion but not force and timing of operant responding.
Topics: Amphetamine; Animals; Apomorphine; Conditioning, Operant; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats | 1998 |
Comparison of mesencephalic free-floating tissue culture grafts and cell suspension grafts in the 6-hydroxydopamine-lesioned rat.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Tissue Transplantation; Calcium-Binding Proteins; Cell Count; Cell Culture Techniques; Cells, Cultured; Female; Fetal Tissue Transplantation; Graft Survival; Mesencephalon; Neurons; Oxidopamine; Pregnancy; Rats; Rats, Sprague-Dawley; Sympatholytics; Sympathomimetics; Time Factors; Tyrosine 3-Monooxygenase | 1998 |
Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions.
Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Carrier Proteins; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Iodine Radioisotopes; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Fibers; Nerve Tissue Proteins; Neuropeptides; Neurotransmitter Agents; Oxidopamine; Parkinson Disease, Secondary; Prosencephalon; Radioimmunoassay; Rats; Rats, Wistar; Substantia Nigra; Sulpiride; Sympatholytics; Tyrosine 3-Monooxygenase; Ventral Tegmental Area; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 1998 |
The corticostriatal system mediates the "paradoxical" contraversive rotation but not the striatal hyperexpression of Fos induced by amphetamine early after 6-hydroxydopamine lesion of the nigrostriatal pathway.
Topics: Afferent Pathways; Amphetamine; Animals; Attention; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Female; Immunohistochemistry; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rotation; Sensation; Substantia Nigra; Tyrosine 3-Monooxygenase | 1998 |
Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Forelimb; Microinjections; Motor Activity; Nerve Degeneration; Neurons; Oxidopamine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Tyrosine 3-Monooxygenase | 1998 |
Globus pallidus lesions depress the excitatory responses to apomorphine but not amphetamine in the subthalamic nucleus of the behaving rat with a 6-OHDA nigra lesion.
Topics: Amphetamine; Animals; Apomorphine; Evoked Potentials; Globus Pallidus; Male; Motor Activity; Oxidopamine; Rats; Rotation; Substantia Nigra; Thalamic Nuclei | 1998 |
Depletion of dopamine in the nucleus accumbens prevents the generation of locomotion by metabotropic glutamate receptor activation.
Topics: Amphetamine; Animals; Cycloleucine; Dopamine; Locomotion; Male; Microinjections; Nucleus Accumbens; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1998 |
Effects of bilateral ablation or 6-OHDA lesion of the frontal cortex upon the behaviors induced by apomorphine and amphetamine in adult cats.
Topics: Age Factors; Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Catecholamines; Cats; Cerebral Decortication; Dopamine; Dopamine Agents; Dopamine Agonists; Fear; Female; Frontal Lobe; Functional Laterality; Locomotion; Male; Oxidopamine; Prefrontal Cortex; Social Behavior; Sympatholytics | 1998 |
Amphetamine-induced behavior, dopamine release, and c-fos mRNA expression: modulation by environmental novelty.
Topics: Amphetamine; Animals; Behavior, Animal; Caudate Nucleus; Cerebral Cortex; Corticosterone; Dopamine; Environment; Gene Expression; In Situ Hybridization; Male; Microdialysis; Nucleus Accumbens; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor.
Topics: Adenoviridae; Amphetamine; Animals; Behavior, Animal; Body Weight; Cell Survival; Corpus Striatum; DNA, Viral; Dopamine; Dopamine Agents; Enzyme-Linked Immunosorbent Assay; Genetic Therapy; Glial Cell Line-Derived Neurotrophic Factor; Humans; Lac Operon; Male; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Oxidopamine; Rats; Rats, Inbred F344; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substantia Nigra; Sympatholytics; Transgenes | 1998 |
Effect of ventral tegmental 6-hydroxydopamine lesions on the locomotor stimulant action of nicotine in rats.
Topics: Amphetamine; Animals; Autoradiography; Carrier Proteins; Caudate Nucleus; Cocaine; Denervation; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neurons; Nicotine; Nucleus Accumbens; Oxidopamine; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Scopolamine; Tegmentum Mesencephali; Time Factors | 1998 |
Unilateral dopamine depletion paradoxically enhances amphetamine-induced Fos expression in basal ganglia output structures.
Topics: Afferent Pathways; Amphetamine; Animals; Basal Ganglia; Corpus Striatum; Dopamine; Dopamine Agents; Immunohistochemistry; Male; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1999 |
Biochemical and anatomical characterization of forepaw adjusting steps in rat models of Parkinson's disease: studies on medial forebrain bundle and striatal lesions.
Topics: Adaptation, Physiological; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Female; Forelimb; Gait; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 1999 |
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle.
Topics: Amphetamine; Animals; Antibodies; Apomorphine; Atrophy; Body Weight; Cerebral Ventricles; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Agonists; ELAV Proteins; Female; Glial Cell Line-Derived Neurotrophic Factor; Hydrogen-Ion Concentration; Injections, Intraventricular; Nerve Degeneration; Nerve Growth Factors; Nerve Regeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurturin; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 1999 |
Pergolide potentiates L-DOPA-induced dopamine release in rat striatum after lesioning with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Agonists; Drug Synergism; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Motor Activity; Neostriatum; Neurons; Oxidopamine; Parkinson Disease, Secondary; Pergolide; Rats; Rats, Wistar | 1999 |
Rat strain differences in the ability to disrupt sensorimotor gating are limited to the dopaminergic system, specific to prepulse inhibition, and unrelated to changes in startle amplitude or nucleus accumbens dopamine receptor sensitivity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Amphetamine; Animals; Apomorphine; Dopamine; Dopamine Agonists; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Phencyclidine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Dopamine; Reflex, Startle; Species Specificity; Time Factors | 1999 |
Environmental modulation of amphetamine-induced c-fos expression in D1 versus D2 striatal neurons.
Topics: Amphetamine; Animals; Dopamine Uptake Inhibitors; Environment; Gene Expression; Genes, fos; In Situ Hybridization; Male; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Sympatholytics | 1999 |
Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer.
Topics: Adrenergic Agents; Amphetamine; Animals; Brain-Derived Neurotrophic Factor; Central Nervous System Stimulants; Gene Transfer Techniques; Genetic Vectors; Humans; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1999 |
The effect of a subchronic post-lesion treatment with (-)-deprenyl on the sensitivity of 6-OHDA-lesioned rats to apomorphine and d-amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Sprague-Dawley; Selegiline | 1999 |
Evaluation of simple and complex sensorimotor behaviours in rats with a partial lesion of the dopaminergic nigrostriatal system.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Denervation; Dopamine; Female; Forelimb; Functional Laterality; Gait; Motor Activity; Oxidopamine; Posture; Psychomotor Performance; Rats; Rotation | 2000 |
Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral mesenc
Topics: Amphetamine; Animals; Apomorphine; Atrophy; Autoradiography; Behavior, Animal; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Fetal Tissue Transplantation; Male; Mazindol; Nerve Degeneration; Neurons; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Substantia Nigra; Sympatholytics; Tritium | 2000 |
Detection of the effects of dopamine receptor supersensitivity using pharmacological MRI and correlations with PET.
Topics: Amphetamine; Animals; Apomorphine; Cerebrovascular Circulation; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Hemodynamics; Magnetic Resonance Imaging; Male; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics; Tomography, Emission-Computed | 2000 |
Intrastriatal and intranigral grafting of hNT neurons in the 6-OHDA rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Cell Count; Cell Line; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Graft Survival; Humans; Lithium Chloride; Motor Activity; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Stem Cell Transplantation; Stem Cells; Substantia Nigra; Teratocarcinoma; Transplantation, Heterologous; Tyrosine 3-Monooxygenase | 2000 |
Simultaneous intrastriatal and intranigral grafting (double grafts) in the rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Tissue Transplantation; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Female; Fetal Tissue Transplantation; Fluorescent Dyes; Gap Junctions; Neural Pathways; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotation; Stilbamidines; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 2000 |
A comparison of two behavioral measures of psychomotor activation following intravenous amphetamine or cocaine: dose- and sensitization-dependent changes.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics | 1999 |
Dopamine transporter function assessed by antisense knockdown in the rat: protection from dopamine neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Amphetamine; Animals; Apomorphine; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Cytoprotection; Dopamine Plasma Membrane Transport Proteins; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Motor Activity; Nerve Tissue Proteins; Oligonucleotides, Antisense; Oxidopamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Tritium | 2000 |
Environmental modulation of the response to amphetamine: dissociation between changes in behavior and changes in dopamine and glutamate overflow in the rat striatal complex.
Topics: Amphetamine; Animals; Apomorphine; Aspartic Acid; Behavior, Animal; Central Nervous System Stimulants; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Environment; Glutamic Acid; Male; Microdialysis; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Sympatholytics | 2000 |
Farnesyl-L-cysteine analogs block SAM-induced Parkinson's disease-like symptoms in rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Chromatography, Gel; Cysteine; Freeze Drying; Male; Methylation; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Stereotyped Behavior; Sympathectomy, Chemical; Tremor | 2000 |
Simultaneous intrastriatal and intranigral dopaminergic grafts in the parkinsonian rat model: role of the intranigral graft.
Topics: Amphetamine; Animals; Brain Tissue Transplantation; Denervation; Disease Models, Animal; Dopamine; Female; Motor Activity; Neostriatum; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Recovery of Function; Rotation; Substantia Nigra; Time Factors | 2000 |
Disruption of acquisition and performance of operant response-duration differentiation by unilateral nigrostriatal lesions.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Conditioning, Operant; Corpus Striatum; Dopamine Agents; Histocytochemistry; Image Processing, Computer-Assisted; Levodopa; Male; Oxidopamine; Rats; Rats, Long-Evans; Reinforcement Schedule; Stereotaxic Techniques; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase | 2000 |
Modulation of latent inhibition in the rat by altered dopamine transmission in the nucleus accumbens at the time of conditioning.
Topics: Amphetamine; Animals; Association Learning; Behavior, Animal; Brain Diseases; Conditioning, Psychological; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Injections; Injections, Intraperitoneal; Male; Neural Inhibition; Nucleus Accumbens; Oxidopamine; Rats; Rats, Sprague-Dawley; Reaction Time; Synaptic Transmission | 2000 |
Environmental novelty differentially affects c-fos mRNA expression induced by amphetamine or cocaine in subregions of the bed nucleus of the stria terminalis and amygdala.
Topics: Amphetamine; Amygdala; Animals; Apomorphine; Behavior, Animal; Cocaine; Corpus Striatum; Environment; In Situ Hybridization; Male; Microinjections; Motor Activity; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Septal Nuclei | 2001 |
Influence of time in culture and BDNF pretreatment on survival and function of grafted embryonic rat ventral mesencephalon in the 6-OHDA rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Tissue Transplantation; Brain-Derived Neurotrophic Factor; Cell Count; Cell Survival; Cells, Cultured; Corpus Striatum; Culture Techniques; Disease Models, Animal; Female; Fetal Tissue Transplantation; Graft Survival; Mesencephalon; Nerve Fibers; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2001 |
Neuroprotective effect of vitamin E on the early model of Parkinson's disease in rat: behavioral and histochemical evidence.
Topics: Amphetamine; Animals; Apomorphine; Atrophy; Axonal Transport; Corpus Striatum; Disease Models, Animal; Male; Motor Activity; Neurons; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Vitamin E; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 2001 |
Effect of 6-hydroxydopamine or repeated amphetamine treatment on mesencephalic mRNA levels for AMPA glutamate receptor subunits in the rat.
Topics: Adrenergic Agents; Amphetamine; Animals; Male; Motor Activity; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Substantia Nigra; Sympatholytics; Ventral Tegmental Area | 2001 |
Entopeduncular lesions facilitate and thalamic lesions depress spontaneous and drug-evoked motor behavior in the hemiparkinsonian rat.
Topics: Amphetamine; Animals; Apomorphine; Denervation; Disease Models, Animal; Dopamine Agonists; Dyskinesia, Drug-Induced; Entopeduncular Nucleus; Male; Motor Cortex; Neural Inhibition; Neural Pathways; Neurosurgical Procedures; Oxidopamine; Parkinsonian Disorders; Rats; Thalamus; Ventral Thalamic Nuclei | 2001 |
Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease.
Topics: Amphetamine; Animals; Corpus Striatum; Dopamine; Female; Glial Cell Line-Derived Neurotrophic Factor; Infusion Pumps; Injections, Intraventricular; Motor Activity; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2001 |
A force-plate actometer for quantitating rodent behaviors: illustrative data on locomotion, rotation, spatial patterning, stereotypies, and tremor.
Topics: Amphetamine; Animals; Behavior, Animal; Biomechanical Phenomena; Central Nervous System; Dopamine Uptake Inhibitors; Locomotion; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Neurophysiology; Oxidopamine; Rats; Rats, Sprague-Dawley; Rodentia; Signal Processing, Computer-Assisted; Space Perception; Stereotypic Movement Disorder; Tremor | 2001 |
Regeneration of dopaminergic function in 6-hydroxydopamine-lesioned rats by neuroimmunophilin ligand treatment.
Topics: Amphetamine; Animals; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ligands; Long-Term Potentiation; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Recovery of Function; Substantia Nigra; Synaptic Transmission; Tacrolimus Binding Protein 1A; Tyrosine 3-Monooxygenase | 2001 |
Blockade of subthalamic glutamatergic activity corrects changes in neuronal metabolism and motor behavior in rats with nigrostriatal lesions.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Energy Metabolism; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Male; Motor Activity; Neostriatum; Neural Pathways; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra; Subthalamic Nucleus; Succinate Dehydrogenase; Sympatholytics; Synaptic Transmission | 2001 |
Restorative plasticity of dopamine neuronal transplants depends on the degree of hemispheric dominance.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dominance, Cerebral; Dopamine; Female; Fetal Tissue Transplantation; Forelimb; Functional Laterality; Graft Survival; Medial Forebrain Bundle; Mesencephalon; Motor Skills; Neuronal Plasticity; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Recovery of Function; Tyrosine 3-Monooxygenase | 2001 |
Differential effects of unilateral striatal and nigrostriatal lesions on grip strength, skilled paw reaching and drug-induced rotation in the rat.
Topics: Amphetamine; Animals; Apomorphine; Central Nervous System Stimulants; Corpus Striatum; Denervation; Dopamine Agonists; Female; Functional Laterality; Hand Strength; Motor Activity; Oxidopamine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Sympatholytics | 2001 |
NAIP protects the nigrostriatal dopamine pathway in an intrastriatal 6-OHDA rat model of Parkinson's disease.
Topics: Amphetamine; Amyloid beta-Protein Precursor; Animals; Antibodies; Caspase 3; Caspases; Cell Survival; Disease Models, Animal; DNA Fragmentation; Dopamine; Fluorescent Dyes; Genetic Vectors; Immunohistochemistry; Male; Movement Disorders; Neostriatum; Nerve Degeneration; Nerve Tissue Proteins; Neural Pathways; Neuronal Apoptosis-Inhibitory Protein; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics | 2001 |
Dopamine D3 receptors are involved in amphetamine-induced contralateral rotation in 6-OHDA lesioned rats.
Topics: Adrenergic Agents; Amphetamine; Animals; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Indans; Male; Medial Forebrain Bundle; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3 | 2001 |
Antiparkinson-like effects of a novel neurotensin analog in unilaterally 6-hydroxydopamine lesioned rats.
Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Motor Activity; Neurotensin; Oxidopamine; Parkinson Disease, Secondary; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2001 |
Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glial Cell Line-Derived Neurotrophic Factor; Hedgehog Proteins; Humans; Microinjections; Motor Activity; Myristic Acid; Nerve Growth Factors; Nerve Tissue Proteins; Organ Specificity; Oxidopamine; Parkinson Disease, Secondary; Peptide Fragments; Rats; Trans-Activators; Tyrosine 3-Monooxygenase | 2002 |
Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model.
Topics: Adrenergic Agents; Amphetamine; Animals; Cell Culture Techniques; Cell Transplantation; Dopamine; Dopamine Agents; Embryo, Mammalian; Immunohistochemistry; Ligands; Neurons; Oxidopamine; Parkinson Disease; Rats; Stem Cells; Time Factors; Tomography, Emission-Computed | 2002 |
Drug-induced rotation intensity in unilateral dopamine-depleted rats is not correlated with end point or qualitative measures of forelimb or hindlimb motor performance.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Agonists; Female; Forelimb; Hindlimb; Levodopa; Motor Activity; Motor Skills; Oxidopamine; Psychomotor Performance; Rats; Rats, Long-Evans; Rotation; Stereotyped Behavior; Substantia Nigra | 2002 |
Behavioral and subthalamic effects of combining a fetal ventral mesencephalic transplant in striatum with an electrolytic lesion of the entopeduncular nucleus in the rat with a unilateral 6-OHDA lesion of substantia nigra.
Topics: Amphetamine; Animals; Corpus Striatum; Entopeduncular Nucleus; Fetal Tissue Transplantation; Male; Mesencephalon; Motor Activity; Oxidopamine; Rats; Substantia Nigra; Subthalamus | 2003 |
Norepinephrine in the prefrontal cortex is critical for amphetamine-induced reward and mesoaccumbens dopamine release.
Topics: Amphetamine; Animals; Behavior, Animal; Conditioning, Psychological; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Male; Mice; Mice, Inbred C57BL; Microdialysis; Motor Activity; Norepinephrine; Nucleus Accumbens; Oxidopamine; Piperazines; Prefrontal Cortex; Reward; Spatial Behavior | 2003 |
Dopamine depletion of the nucleus accumbens reverses isolation-induced deficits in prepulse inhibition in rats.
Topics: Acoustic Stimulation; Adrenergic Agents; Amphetamine; Animals; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Female; Motor Activity; Neural Inhibition; Nucleus Accumbens; Oxidopamine; Rats; Rats, Long-Evans; Reflex, Startle; Social Isolation | 2003 |
Dopamine depletion abolishes apomorphine- and amphetamine-induced increases in extracellular serotonin levels in the striatum of conscious rats: a microdialysis study.
Topics: Afferent Pathways; Amphetamine; Animals; Apomorphine; Binding, Competitive; Carrier Proteins; Denervation; Disease Models, Animal; Dopamine; Dopamine Agonists; Extracellular Matrix; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Neostriatum; Nerve Tissue Proteins; Neuronal Plasticity; Oxidopamine; Parkinsonian Disorders; Paroxetine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptic Transmission | 2003 |
Subchronic caffeine exposure induces sensitization to caffeine and cross-sensitization to amphetamine ipsilateral turning behavior independent from dopamine release.
Topics: Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dopamine; Drug Administration Schedule; Drug Interactions; Functional Laterality; Male; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Stimulation, Chemical; Sympatholytics; Time Factors | 2003 |
Segregation of amphetamine reward and locomotor stimulation between nucleus accumbens medial shell and core.
Topics: Amphetamine; Animals; Autoradiography; Behavior, Animal; Binding, Competitive; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Morphine; Motor Activity; Narcotics; Nerve Tissue Proteins; Neurons; Nucleus Accumbens; Oxidopamine; Rats; Rats, Long-Evans; Reward; Serotonin Plasma Membrane Transport Proteins; Spatial Behavior | 2003 |
Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpc.
Topics: Amphetamine; Animals; Behavior, Animal; Binding, Competitive; Biological Transport; Cell Count; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electrochemistry; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Regeneration; Nerve Tissue Proteins; Oxidopamine; Presynaptic Terminals; Quinpirole; Rats; Rats, Wistar; Substantia Nigra; Synaptosomes | 2003 |
Environmental context and drug history modulate amphetamine-induced c-fos mRNA expression in the basal ganglia, central extended amygdala, and associated limbic forebrain.
Topics: Adrenergic Uptake Inhibitors; AIDS-Related Complex; Amphetamine; Amygdala; Animals; Basal Ganglia; Behavior, Animal; Drug Administration Routes; Drug Interactions; Environment; Gene Expression Regulation; In Situ Hybridization; Male; Oxidopamine; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rotation | 2003 |
Treatment effects on nigrostriatal projection integrity in partial 6-OHDA lesions: comparison of L-DOPA and pramipexole.
Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Autoradiography; Behavior, Animal; Benzothiazoles; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Pramipexole; Rats; Rats, Sprague-Dawley; Substantia Nigra; Thiazoles; Treatment Outcome; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2003 |
Dopamine in the medial prefrontal cortex controls genotype-dependent effects of amphetamine on mesoaccumbens dopamine release and locomotion.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Desipramine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Genotype; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microdialysis; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Species Specificity; Time Factors | 2004 |
Stimulation of postsynaptic alpha1b- and alpha2-adrenergic receptors amplifies dopamine-mediated locomotor activity in both rats and mice.
Topics: Adrenergic Agents; Amphetamine; Animals; Behavior, Animal; Benzopyrans; Cerebellum; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Hyperkinesis; Imidazoles; Locomotion; Male; Mice; Mice, Knockout; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Time Factors | 2003 |
Uptake of 6-[18F]fluoro-L-dopa and [18F]CFT reflect nigral neuronal loss in a rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Behavior, Animal; Brain; Brain Mapping; Central Nervous System Stimulants; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine Agonists; Functional Laterality; Immunohistochemistry; Levodopa; Male; Oxidopamine; Parkinson Disease; Propionates; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 2004 |
Adenosine A2A receptors in neuroadaptation to repeated dopaminergic stimulation: implications for the treatment of dyskinesias in Parkinson's disease.
Topics: Adenosine A2 Receptor Antagonists; Amphetamine; Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agonists; Drug Tolerance; Dyskinesia, Drug-Induced; Humans; Levodopa; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Purines; Pyrimidines; Receptor, Adenosine A2A; Synapses; Triazoles | 2003 |
The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder.
Topics: Amphetamine; Animals; Animals, Outbred Strains; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Central Nervous System Stimulants; Corpus Striatum; Denervation; Disease Models, Animal; Male; Methylphenidate; Mice; Mice, Knockout; Motor Activity; Neural Pathways; Oxidopamine; Phenotype; Receptors, Dopamine D2; Receptors, Dopamine D4; Substantia Nigra; Sympatholytics | 2004 |
Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease.
Topics: Amphetamine; Animals; Cell Survival; Disease Models, Animal; Dopamine; Immunohistochemistry; Mice; Mice, Mutant Strains; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease; Presynaptic Terminals; Substantia Nigra; Wallerian Degeneration | 2004 |
Experimental parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: a modulator of endocannabinoid function.
Topics: Acyltransferases; Amidohydrolases; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Arachidonic Acids; Behavior, Animal; Brain Chemistry; Cell Count; Central Nervous System Stimulants; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Endocannabinoids; Functional Laterality; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Rotation; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Tyrosine 3-Monooxygenase | 2004 |
Long-term effect of intra-striatal glial cell line-derived neurotrophic factor-releasing microspheres in a partial rat model of Parkinson's disease.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Corpus Striatum; Disease Models, Animal; Female; Glial Cell Line-Derived Neurotrophic Factor; Immunohistochemistry; Microspheres; Nerve Growth Factors; Nerve Regeneration; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Stereotyped Behavior; Time; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson's disease.
Topics: Adrenergic Agents; Amphetamine; Animals; Behavior, Animal; Body Weight; Brain; Capsules; Cell Count; Cell Death; Cells, Cultured; Central Nervous System Stimulants; Cricetinae; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Kidney; Laminin; Laser-Doppler Flowmetry; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Neuropilins; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Semaphorin-3A; Stereotyped Behavior; Time Factors; Transfection; Transplants; Tubulin; Tyrosine 3-Monooxygenase; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2004 |
An in vitro interval before transplantation of mesencephalic reaggregates does not compromise survival or functionality.
Topics: Amphetamine; Animals; Brain Tissue Transplantation; Cell Count; Cell Survival; Cells, Cultured; Disease Models, Animal; Dopamine Agents; Fetal Tissue Transplantation; Graft Survival; Male; Mesencephalon; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Inbred F344; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
Behavioral and neurochemical effects of noradrenergic depletions with N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine in 6-hydroxydopamine-induced rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzylamines; Brain Chemistry; Catalepsy; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Locus Coeruleus; Male; Motor Activity; Norepinephrine; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Serotonin; Statistics, Nonparametric; Tyrosine | 2004 |
In vivo characterization of somatodendritic dopamine release in the substantia nigra of 6-hydroxydopamine-lesioned rats.
Topics: Amphetamine; Animals; Cell Count; Dendrites; Dopamine; Dopamine Uptake Inhibitors; Extracellular Fluid; Male; Medial Forebrain Bundle; Microdialysis; Neurons; Oxidopamine; Rats; Rats, Wistar; Sodium Channel Blockers; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2004 |
Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Cell Count; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Extracellular Space; Homovanillic Acid; Immunohistochemistry; Male; Microdialysis; Oxidopamine; Physical Conditioning, Animal; Psychomotor Performance; Rats; Rats, Long-Evans; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
Elevated serotonin is involved in hyperactivity but not in the paradoxical effect of amphetamine in mice neonatally lesioned with 6-hydroxydopamine.
Topics: Amphetamine; Animals; Animals, Newborn; Carrier Proteins; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fenclonine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tryptophan Hydroxylase | 2004 |
Behavioral and anatomical effects of quinolinic acid in the striatum of the hemiparkinsonian rat.
Topics: Adrenergic Agents; Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Huntington Disease; Locomotion; Male; Neurotoxins; Oxidopamine; Parkinson Disease; Quinolinic Acid; Rats; Rotation; Stereotyped Behavior; Substantia Nigra | 2005 |
Dissociation between short-term increased graft survival and long-term functional improvements in Parkinsonian rats overexpressing glial cell line-derived neurotrophic factor.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Cell Transplantation; Corpus Striatum; Disease Models, Animal; Embryo, Mammalian; Female; Glial Cell Line-Derived Neurotrophic Factor; Graft Survival; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Growth Factors; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Recovery of Function; Rotarod Performance Test; Stereotaxic Techniques; Stereotyped Behavior; Time Factors; Tyrosine 3-Monooxygenase; Upper Extremity; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2004 |
Early transplantation of an encapsulated glial cell line-derived neurotrophic factor-producing cell demonstrating strong neuroprotective effects in a rat model of Parkinson disease.
Topics: Adrenergic Agents; Amphetamine; Animals; Behavior, Animal; Cell Line; Cell Transplantation; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Transfer Techniques; Glial Cell Line-Derived Neurotrophic Factor; Immunohistochemistry; In Vitro Techniques; Nerve Growth Factors; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Polymers; Rats; Rats, Sprague-Dawley; Rotation; Time Factors | 2005 |
Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Agents; Amphetamine; Animals; Behavior, Animal; Disruptive, Impulse Control, and Conduct Disorders; Dopamine; Dose-Response Relationship, Drug; Down-Regulation; Male; Neural Pathways; Norepinephrine; Nucleus Accumbens; Oxidopamine; Piperazines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2005 |
Impaired acquisition of skilled behavior in rotarod task by moderate depletion of striatal dopamine in a pre-symptomatic stage model of Parkinson's disease.
Topics: Amphetamine; Animals; Behavior, Animal; Cell Count; Cell Survival; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine; Exploratory Behavior; Functional Laterality; Hindlimb Suspension; Immunohistochemistry; Male; Medial Forebrain Bundle; Microdialysis; Motor Activity; Motor Skills; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Regression Analysis; Rotarod Performance Test; Substantia Nigra; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
The differences between high and low-dose administration of VEGF to dopaminergic neurons of in vitro and in vivo Parkinson's disease model.
Topics: Amphetamine; Animals; Cell Survival; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Implants; Female; In Vitro Techniques; Mesencephalon; Mice; Mice, Inbred C57BL; Neostriatum; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Vascular Endothelial Growth Factor A | 2005 |
Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Catecholamines; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Ginkgo biloba; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Immunohistochemistry; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Plant Extracts; Psychomotor Performance; Rats; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior; Substantia Nigra; Thiobarbituric Acid Reactive Substances; Tyrosine 3-Monooxygenase | 2005 |
Long distance selective fiber outgrowth of transplanted hNT neurons in white matter tracts of the adult rat brain.
Topics: Adrenergic Agents; Amphetamine; Animals; Axons; Behavior, Animal; Cell Differentiation; Cell Line, Tumor; Cell Transplantation; Corpus Striatum; Cyclosporine; Female; Functional Laterality; Graft Survival; Humans; Immunosuppressive Agents; Motor Activity; Nerve Fibers; Neural Pathways; Neurites; Neurons; Oxidopamine; Phosphopyruvate Hydratase; Random Allocation; Rats; Rats, Wistar; Rotarod Performance Test; Substantia Nigra; Teratocarcinoma; Transplantation, Heterologous; Tyrosine 3-Monooxygenase | 2005 |
Postural changes after lesions of the substantia nigra pars reticulata in hemiparkinsonian monkeys.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Callithrix; Cell Count; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Female; Functional Laterality; Immunohistochemistry; Kainic Acid; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Posture; Psychomotor Performance; Reaction Time; Substantia Nigra; Tyrosine 3-Monooxygenase | 2005 |
Effect of AdGDNF on dopaminergic neurotransmission in the striatum of 6-OHDA-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Interactions; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Male; Microdialysis; Nerve Growth Factors; Oxidopamine; Potassium Chloride; Rats; Rats, Inbred F344; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified Neurturin construct.
Topics: Amphetamine; Analysis of Variance; Animals; Blotting, Western; Cell Count; Cell Line; Cloning, Molecular; Conotoxins; Dopamine; Dopamine Uptake Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; Gene Expression Regulation; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor Receptors; Humans; Immunohistochemistry; Lentivirus; Nerve Growth Factors; Neurons; Neuroprotective Agents; Neurturin; Oxidopamine; Parkinson Disease, Secondary; Pigment Epithelium of Eye; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Substantia Nigra; Transfection; Tyrosine 3-Monooxygenase | 2005 |
Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Cell Count; Disease Models, Animal; Drug Interactions; Exploratory Behavior; Female; Functional Laterality; Immunohistochemistry; Linear Models; Medial Forebrain Bundle; Mice; Mice, Inbred CBA; Motor Activity; Neurons; Oxidopamine; Parkinson Disease; Predictive Value of Tests; Psychomotor Performance; Rotarod Performance Test; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2005 |
Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion.
Topics: Adrenergic Agents; Amphetamine; Animals; Dopamine; Electron Transport Complex I; Enzyme Inhibitors; Exploratory Behavior; Functional Laterality; Medial Forebrain Bundle; Microinjections; Motor Activity; Neurons; Oxidopamine; Parkinsonian Disorders; Posture; Rats; Rotarod Performance Test; Rotenone; Stereotyped Behavior; Substantia Nigra | 2005 |
Alterations in the proportions of skeletal muscle proteins following a unilateral lesion to the substantia nigra pars compacta of rats.
Topics: Amphetamine; Animals; Blister; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle Proteins; Muscle, Skeletal; Oxidopamine; Rats; Rats, Wistar; Rotation; Substantia Nigra | 2005 |
Neurorescue effects of VEGF on a rat model of Parkinson's disease.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain; Cell Count; Cell Transplantation; Cells, Cultured; Cricetinae; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Female; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Laminin; Mesencephalon; Mice; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotation; Time Factors; Transfection; Tyrosine 3-Monooxygenase; Vascular Endothelial Growth Factor A | 2005 |
Transplants of neurosphere cell suspensions from aged mice are functional in the mouse model of Parkinson's.
Topics: Aging; Amphetamine; Animals; Apomorphine; Astrocytes; Behavior, Animal; Behavioral Symptoms; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Functional Laterality; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurofilament Proteins; Neurons; Oxidopamine; Parkinson Disease; Stem Cell Transplantation; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Olfactory ensheathing glial co-grafts improve functional recovery in rats with 6-OHDA lesions.
Topics: Amphetamine; Animals; Apomorphine; Astrocytes; Behavior, Animal; Brain; Cell Culture Techniques; Cell Transplantation; Dopamine; Immunohistochemistry; Male; Mesencephalon; Models, Animal; Myelin Sheath; Nerve Regeneration; Neuroglia; Olfactory Bulb; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Recovery of Function | 2005 |
Coordinated and spatial upregulation of arc in striatonigral neurons correlates with L-dopa-induced behavioral sensitization in dyskinetic rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic Agents; AIDS-Related Complex; Amphetamine; Analgesics, Non-Narcotic; Animals; Antiparkinson Agents; Behavior, Animal; Carrier Proteins; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Drug Interactions; Dynorphins; Dyskinesia, Drug-Induced; Functional Laterality; Homer Scaffolding Proteins; Immunohistochemistry; In Situ Hybridization; Levodopa; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oxidopamine; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation | 2005 |
Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Astrocytes; Cell Count; Cell Transplantation; Cells, Cultured; Central Nervous System Stimulants; Enzyme-Linked Immunosorbent Assay; Female; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Immunohistochemistry; Lentivirus; Nerve Fibers; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra; Sympatholytics; Transduction, Genetic | 2005 |
Delivery of sonic hedgehog or glial derived neurotrophic factor to dopamine-rich grafts in a rat model of Parkinson's disease using adenoviral vectors Increased yield of dopamine cells is dependent on embryonic donor age.
Topics: Adenoviridae; Amphetamine; Animals; Cell Count; Disease Models, Animal; Dopamine; Female; Fetal Tissue Transplantation; Genetic Therapy; Gestational Age; Glial Cell Line-Derived Neurotrophic Factor; Hedgehog Proteins; Mesencephalon; Motor Activity; Oxidopamine; Parkinson Disease; Pregnancy; Rats; Rats, Sprague-Dawley; Sympatholytics; Sympathomimetics; Trans-Activators | 2005 |
Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy.
Topics: Amphetamine; Animals; Disease Models, Animal; Dopamine; Female; Fetal Tissue Transplantation; Male; Mesencephalon; Motor Activity; Multiple System Atrophy; Nerve Regeneration; Oxidopamine; Parkinson Disease; Pregnancy; Rats; Rats, Wistar; Sympatholytics; Sympathomimetics; Transplantation, Homologous | 2005 |
Enriched environment induces cellular plasticity in the adult substantia nigra and improves motor behavior function in the 6-OHDA rat model of Parkinson's disease.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Antigens; Behavior, Animal; Bromodeoxyuridine; Cell Count; Cell Proliferation; Central Nervous System Stimulants; Disease Models, Animal; Environment; Female; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Motor Activity; Neuronal Plasticity; Oxidopamine; Parkinson Disease; Proteoglycans; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2006 |
The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat.
Topics: Amphetamine; Animals; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Female; Levodopa; Movement; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotation; Selective Serotonin Reuptake Inhibitors; Substantia Nigra; Transplantation Tolerance | 2006 |
6-Hydroxydopamine lesions of nucleus accumbens core abolish amphetamine-induced conditioned activity.
Topics: Amphetamine; Animals; Behavior, Animal; Binding, Competitive; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Motor Activity; Nucleus Accumbens; Oxidopamine; Radiopharmaceuticals; Rats; Rats, Long-Evans; Sympatholytics; Tritium | 2006 |
Relation between rotation in the 6-OHDA lesioned rat and dopamine loss in striatal and substantia nigra subregions.
Topics: Amphetamine; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Putamen; Rats; Rotation; Substantia Nigra; Tyrosine 3-Monooxygenase | 2006 |
Trichopus zeylanicus combats fatigue without amphetamine-mimetic activity.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Chronic Disease; Dioscoreaceae; Fatigue; Fatigue Syndrome, Chronic; Male; Mice; Mice, Mutant Strains; Oxidopamine; Physical Exertion; Phytotherapy; Plant Preparations; Powders; Rats; Rats, Sprague-Dawley; Swimming; Sympatholytics; Sympathomimetics | 2006 |
Transplantation of human neural precursor cells in the 6-OHDA lesioned rats: effect of immunosuppression with cyclosporine A.
Topics: Amphetamine; Animals; Astrocytes; Cell Proliferation; Cyclosporine; Dopamine Uptake Inhibitors; Graft Survival; Humans; Immunohistochemistry; Immunosuppressive Agents; Macrophage Activation; Mesencephalon; Microglia; Neurons; Oxidopamine; Rats; Rotation; Stem Cell Transplantation; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics; Transplantation, Heterologous; Tyrosine 3-Monooxygenase | 2006 |
Aripiprazole and its human metabolite are partial agonists at the human dopamine D2 receptor, but the rodent metabolite displays antagonist properties.
Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Binding, Competitive; Biotransformation; Catalepsy; CHO Cells; Cricetinae; Cricetulus; Dopamine D2 Receptor Antagonists; Dyskinesia, Drug-Induced; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; Male; Motor Activity; Oxidopamine; Piperazines; Quinolones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Species Specificity; Transfection | 2006 |
Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease.
Topics: Amphetamine; Animals; Cell Death; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Dopamine; Female; Gliosis; Inflammation Mediators; Motor Activity; Nerve Degeneration; Neurons; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Signal Transduction; Substantia Nigra; Treatment Outcome; Tumor Necrosis Factor-alpha | 2006 |
Improvements in motor behavioral tests during deep brain stimulation of the subthalamic nucleus in rats with different degrees of unilateral parkinsonism.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Deep Brain Stimulation; Disease Models, Animal; Electric Stimulation Therapy; Electrodes; Functional Laterality; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Rotation; Subthalamic Nucleus | 2006 |
Substantia nigra compacta neurons that innervate the reticular thalamic nucleus in the rat also project to striatum or globus pallidus: implications for abnormal motor behavior.
Topics: Adrenergic Agents; Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Dextrans; Dopamine; Dopamine Agents; Functional Laterality; Globus Pallidus; Immunohistochemistry; Male; Motor Activity; Neural Pathways; Neurons; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra; Thalamic Nuclei; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
Bridging nigrostriatal pathway with fibroblast growth factor-primed peripheral nerves and fetal ventral mesencephalon transplant recuperates from deficits in parkinsonian rats.
Topics: Amphetamine; Animals; Behavior, Animal; Cell Transplantation; Corpus Striatum; Fetus; Fibroblast Growth Factors; Immunohistochemistry; Mesencephalon; Nerve Fibers; Oxidopamine; Parkinson Disease; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2006 |
Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,6-Dihydroxytryptamine; Age Factors; Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Hydroxyindoleacetic Acid; Male; Microdialysis; Oxidopamine; Piperazines; Pregnancy; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Sympatholytics | 2007 |
Changes in brain functional activation during resting and locomotor states after unilateral nigrostriatal damage in rats.
Topics: Amphetamine; Animals; Autoradiography; Brain; Brain Damage, Chronic; Brain Mapping; Central Nervous System Stimulants; Cerebellum; Functional Laterality; Globus Pallidus; Image Processing, Computer-Assisted; Locomotion; Male; Models, Neurological; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Rest; Subthalamic Nucleus; Tyrosine 3-Monooxygenase; Walking | 2007 |
Lesions of dopaminergic neurons in the substantia nigra pars compacta and in the ventral tegmental area enhance depressive-like behavior in rats.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Depression; Disease Models, Animal; Functional Laterality; Helplessness, Learned; Levodopa; Male; Nerve Degeneration; Neurons; Oxidopamine; Rats; Rats, Wistar; Reaction Time; Rotarod Performance Test; Substantia Nigra; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2007 |
Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Cell Differentiation; Cells, Cultured; Central Nervous System Stimulants; Data Interpretation, Statistical; Dopamine; Enzyme-Linked Immunosorbent Assay; Glial Cell Line-Derived Neurotrophic Factor; Humans; Immunohistochemistry; Insulin-Like Growth Factor I; Lentivirus; Male; Nerve Fibers; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Lew; Stem Cell Transplantation; Stem Cells; Stereotyped Behavior; Sympatholytics; Tyrosine 3-Monooxygenase | 2008 |
Adjunctive use of the non-ionic surfactant Poloxamer 188 improves fetal dopaminergic cell survival and reinnervation in a neural transplantation strategy for Parkinson's disease.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Cell Survival; Cell Transplantation; Cells, Cultured; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Embryo, Mammalian; Female; In Vitro Techniques; Mesencephalon; Nerve Fibers; Neurons; Oxidopamine; Parkinson Disease; Poloxamer; Rats; Surface-Active Agents; Time Factors; Tyrosine 3-Monooxygenase | 2008 |
The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram.
Topics: Adrenal Cortex Hormones; Amphetamine; Animals; Anxiety; Blotting, Western; Body Weight; Central Nervous System Stimulants; Citalopram; Dopamine Agents; Drinking; Dyskinesia, Drug-Induced; Image Processing, Computer-Assisted; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin; Stereotyped Behavior; Sympatholytics; Synaptic Transmission | 2008 |
Sigma ligands, but not N-methyl-D-aspartate antagonists, reduce levodopa-induced dyskinesias.
Topics: Adrenergic Agents; Amphetamine; Animals; Anti-Anxiety Agents; Behavior, Animal; Dextromethorphan; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Levodopa; Ligands; Male; N-Methylaspartate; Neurotoxicity Syndromes; Oxidopamine; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |
Lack of robust protective effect of quercetin in two types of 6-hydroxydopamine-induced parkinsonian models in rats and dopaminergic cell cultures.
Topics: Amphetamine; Animals; Antioxidants; Apomorphine; Behavior, Animal; Cell Line, Tumor; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Male; Motor Activity; Neuroblastoma; Oxidopamine; Parkinson Disease; Quercetin; Rats; Rats, Wistar; Substantia Nigra; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 2008 |
Behavioural effects of trishomocubanes in rats with unilateral 6-hydroxydopamine lesions.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Bridged-Ring Compounds; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Female; Functional Laterality; Maze Learning; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Posture; Rats; Rats, Sprague-Dawley; Receptors, sigma; Vibrissae | 2008 |
Functional effect of FGF2- and FGF8-expanded ventral mesencephalic precursor cells in a rat model of Parkinson's disease.
Topics: Adrenergic Agents; Amphetamine; Animals; Behavior, Animal; Cells, Cultured; Central Nervous System Stimulants; Disease Models, Animal; Embryo, Mammalian; Female; Fetal Tissue Transplantation; Fibroblast Growth Factor 2; Fibroblast Growth Factor 8; Mesencephalon; Motor Activity; Neostriatum; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Stem Cells; Time Factors; Tyrosine 3-Monooxygenase | 2008 |
Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats.
Topics: Amphetamine; Animals; Behavior, Animal; Brain; Cell Nucleus; Cells, Cultured; Cytoplasm; Dependovirus; Female; Forelimb; Genes, Dominant; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Immunoenzyme Techniques; Male; Nerve Degeneration; Neurons; Oxidopamine; Parkinson Disease; Protein Transport; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Substantia Nigra; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2008 |
Cabergoline and pramipexole fail to modify already established dyskinesias in an animal model of parkinsonism.
Topics: Amphetamine; Animals; Antiparkinson Agents; Behavior, Animal; Benzothiazoles; Cabergoline; Disease Models, Animal; Dopamine Antagonists; Drug Interactions; Dyskinesia, Drug-Induced; Ergolines; Female; Levodopa; Mesencephalon; Oxidopamine; Parkinsonian Disorders; Pramipexole; Rats; Rats, Wistar; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 2008 |
The synaptic impact of the host immune response in a parkinsonian allograft rat model: Influence on graft-derived aberrant behaviors.
Topics: Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Dyskinesias; Histocompatibility Antigens Class II; Levodopa; Male; Microscopy, Electron, Transmission; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Synapses; Tissue Transplantation; Tyrosine 3-Monooxygenase | 2008 |
Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease.
Topics: Adrenergic Agents; Amphetamine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Antiparkinson Agents; Brain Tissue Transplantation; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dyskinesias; Embryo, Mammalian; Encephalitis; Female; Interleukin-2; Interleukin-2 Receptor alpha Subunit; Levodopa; Mesencephalon; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rats, Wistar; Skin Transplantation | 2008 |
Neurochemical changes in the striatum of dyskinetic rats after administration of the cannabinoid agonist WIN55,212-2.
Topics: Amphetamine; Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Corpus Striatum; Dopamine; Dyskinesias; Glutamine; Homovanillic Acid; Levodopa; Male; Morpholines; Naphthalenes; Oxidopamine; Rats; Rats, Wistar | 2009 |
Dopamine-dependent periadolescent maturation of corticostriatal functional connectivity in mouse.
Topics: Action Potentials; Age Factors; Amphetamine; Animals; Animals, Newborn; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Electric Stimulation; Hyperkinesis; Locomotion; Mice; Neural Pathways; Neurons; Oxidopamine; Serotonin | 2009 |
Enriched environment protects the nigrostriatal dopaminergic system and induces astroglial reaction in the 6-OHDA rat model of Parkinson's disease.
Topics: Amphetamine; Analysis of Variance; Animals; Astrocytes; Corpus Striatum; Disease Models, Animal; Dopamine; Environment; Glial Fibrillary Acidic Protein; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotarod Performance Test; Stilbamidines; Substantia Nigra; Tyrosine 3-Monooxygenase | 2009 |
Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Analysis of Variance; Animals; Autoradiography; Cocaine; Conotoxins; Corpus Striatum; Cotinine; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Iodine Isotopes; Male; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotine; Oxidopamine; Protein Binding; Rats; Rats, Sprague-Dawley; Saimiri; Substantia Nigra; Time Factors | 2009 |
Amphetamine-induced abnormal movements occur independently of both transplant- and host-derived serotonin innervation following neural grafting in a rat model of Parkinson's disease.
Topics: 5,7-Dihydroxytryptamine; Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Dopamine Uptake Inhibitors; Dyskinesias; Embryo, Mammalian; Female; Levodopa; Mesencephalon; Oxidopamine; Parkinson Disease; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Transplants; Tyrosine 3-Monooxygenase | 2009 |
Amphetamine-evoked rotation requires newly synthesized dopamine at 14 days but not 1 day after intranigral 6-OHDA and is consistently dissociated from sensorimotor behavior.
Topics: Adrenergic Agents; alpha-Methyltyrosine; Amphetamine; Animals; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Functional Laterality; Hand Strength; Hydrazines; Male; Motor Activity; Oxidopamine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reaction Time; Rotation; Statistics as Topic; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2009 |
Effects of GDNF pretreatment on function and survival of transplanted fetal ventral mesencephalic cells in the 6-OHDA rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Brain; Cell Survival; Cells, Cultured; Central Nervous System Stimulants; Disease Models, Animal; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glial Cell Line-Derived Neurotrophic Factor; Mesenchymal Stem Cell Transplantation; Motor Activity; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Random Allocation; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2009 |
Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats.
Topics: Amphetamine; Animals; Antiparkinson Agents; Brain Tissue Transplantation; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Drug Synergism; Dyskinesia, Drug-Induced; Female; Levodopa; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Sympatholytics | 2009 |
Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors.
Topics: Amphetamine; Analysis of Variance; Animals; Benserazide; Brain; Dopamine Agents; Dyskinesia, Drug-Induced; Humans; In Situ Hybridization; Levodopa; Lipid Peroxidation; Male; Mice; Mice, Knockout; Motor Activity; Neurons; Oxidopamine; Receptor, Cannabinoid, CB1; Severity of Illness Index | 2011 |
Exercise exerts neuroprotective effects on Parkinson's disease model of rats.
Topics: Amphetamine; Animals; Ascorbic Acid; Behavior, Animal; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Proliferation; Corpus Striatum; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Exercise Test; Female; Glial Cell Line-Derived Neurotrophic Factors; Microtubule-Associated Proteins; Movement; Neuropeptides; Oxidopamine; Parkinson Disease, Secondary; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2010 |
6-hydroxydopamine lesions in the rat neostriatum impair sequential learning in a serial reaction time task.
Topics: Amphetamine; Analysis of Variance; Animals; Brain Chemistry; Disease Models, Animal; Freezing Reaction, Cataleptic; Learning Disabilities; Male; Motor Activity; Neostriatum; Neuropsychological Tests; Oxidopamine; Rats; Rats, Wistar; Reaction Time; Serial Learning; Sympatholytics; Time Factors | 2010 |
Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: focusing on neuroprotective effects of stromal cell-derived factor-1alpha.
Topics: Amphetamine; Animals; Biomarkers; Chemokine CXCL12; Corpus Striatum; Cytoprotection; Disease Models, Animal; Dopamine; Female; Graft Survival; Infusions, Intravenous; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Motor Activity; Neurons; Neurotoxins; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2010 |
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Female; Mice; Nerve Degeneration; Neural Pathways; Neuropsychological Tests; Oxidopamine; Parkinson Disease; Substantia Nigra; Sympatholytics | 2010 |
Neurturin protects against 6-hydroxydopamine-induced reductions in evoked dopamine overflow in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Functional Laterality; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Male; Microdialysis; Nerve Growth Factors; Neuroprotective Agents; Neurturin; Oxidopamine; Potassium Chloride; Rats; Rats, Inbred F344; Substantia Nigra; Sympatholytics | 2010 |
Antiparkinsonian trophic action of glial cell line-derived neurotrophic factor and transforming growth factor β1 is enhanced after co-infusion in rats.
Topics: Algorithms; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Blotting, Western; Central Nervous System Stimulants; Dopamine Agonists; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Immunohistochemistry; Infusion Pumps, Implantable; Male; Microinjections; Neostriatum; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Stereotyped Behavior; Sympatholytics; Transforming Growth Factor beta1 | 2010 |
An engineered zinc finger protein activator of the endogenous glial cell line-derived neurotrophic factor gene provides functional neuroprotection in a rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Cell Line; Disease Models, Animal; Dopamine Agents; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factors; Green Fluorescent Proteins; Haplorhini; Humans; Lentivirus; Mice; Microarray Analysis; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Protein Engineering; Rats; RNA, Messenger; Time Factors; Transfection; Tyrosine 3-Monooxygenase; Zinc Fingers | 2010 |
Effects of unilateral 6-OHDA lesions on [3H]-N-propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat.
Topics: Amphetamine; Animals; Apomorphine; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley | 2011 |
Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing.
Topics: Amphetamine; Animals; Conditioning, Psychological; Dopamine; Inhibition, Psychological; Male; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Reaction Time | 2011 |
Vascular endothelial growth factor-B is neuroprotective in an in vivo rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Behavioral Symptoms; Cell Count; Central Nervous System Stimulants; Disease Models, Animal; Functional Laterality; Nerve Degeneration; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Peptides; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Vascular Endothelial Growth Factor B | 2011 |
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats.
Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Cues; Depression; Dopamine Agonists; Male; Memory; Oxidopamine; Parkinson Disease, Secondary; Progesterone; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Stereotyped Behavior; Swimming; Sympatholytics | 2011 |
Androgens exacerbate motor asymmetry in male rats with unilateral 6-hydroxydopamine lesion.
Topics: Adrenergic Agents; Amphetamine; Androgens; Animals; Dopaminergic Neurons; Male; Motor Activity; Neostriatum; Orchiectomy; Oxidative Stress; Oxidopamine; Rats; Rotation; Substantia Nigra; Testosterone | 2011 |
Pimavanserin, a 5-HT2A inverse agonist, reverses psychosis-like behaviors in a rodent model of Parkinson's disease.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Disease Models, Animal; Dyskinesias; Fenfluramine; Fluorobenzenes; Hyperkinesis; Male; Motor Activity; Oxidopamine; Parkinson Disease; Piperidines; Psychotic Disorders; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Sensory Gating; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents; Serotonin Receptor Agonists; Substantia Nigra; Tyrosine 3-Monooxygenase; Urea | 2011 |
Intranasally applied L-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Electrochemistry; Exploratory Behavior; Forelimb; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Motor Activity; Motor Skills; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics | 2012 |
The grid-walking test: assessment of sensorimotor deficits after moderate or severe dopamine depletion by 6-hydroxydopamine lesions in the dorsal striatum and medial forebrain bundle.
Topics: Amphetamine; Animals; Antiparkinson Agents; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Functional Laterality; Levodopa; Male; Medial Forebrain Bundle; Nervous System Diseases; Oxidopamine; Parkinson Disease, Secondary; Psychomotor Performance; Rats; Rats, Wistar; Sympatholytics; Walking | 2012 |
Amphetamine-induced rotation and L-DOPA-induced dyskinesia in the rat 6-OHDA model: a correlation study.
Topics: Amphetamine; Animals; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Levodopa; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation | 2012 |
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
Topics: 5,6-Dihydroxytryptamine; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Buspirone; Cell Count; Creatinine; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Dyskinesia, Drug-Induced; Female; Indoles; Levodopa; Motor Activity; Oxidopamine; Parkinson Disease; Pyridines; Rats; Rats, Sprague-Dawley; Serotonergic Neurons; Serotonin Receptor Agonists; Time Factors | 2012 |
Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms.
Topics: Amphetamine; Analysis of Variance; Animals; Atorvastatin; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Glutathione; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Male; Malondialdehyde; Mitochondria; Motor Activity; NADH Dehydrogenase; Nitrites; Oxidopamine; Parkinsonian Disorders; Pyrroles; Rats; Rats, Wistar; Simvastatin; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
A novel use of combined tyrosine hydroxylase and silver nucleolar staining to determine the effects of a unilateral intrastriatal 6-hydroxydopamine lesion in the substantia nigra: a stereological study.
Topics: Adrenergic Agents; Amphetamine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Functional Laterality; Male; Neurons; Neurotoxicity Syndromes; Oxidopamine; Rats; Rats, Long-Evans; Rotation; Silver Staining; Stereotaxic Techniques; Substantia Nigra; Tyrosine 3-Monooxygenase | 2012 |
Characterisation of spatial neglect induced by unilateral 6-OHDA lesions on a choice reaction time task in rats.
Topics: Amphetamine; Animals; Attention; Central Nervous System Stimulants; Choice Behavior; Disease Models, Animal; Female; Functional Laterality; Motor Activity; Oxidopamine; Perceptual Disorders; Rats; Reaction Time; Rotation; Stereotyped Behavior; Sympatholytics; Tyrosine 3-Monooxygenase | 2013 |
Is nicotine protective against Parkinson's disease? An experimental analysis.
Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Interneurons; Male; Nerve Tissue Proteins; Neuroprotective Agents; Nicotine; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 2012 |
Adult human olfactory epithelial-derived progenitors: a potential autologous source for cell-based treatment for Parkinson's disease.
Topics: Adult; Amphetamine; Animals; Behavior, Animal; Cell Differentiation; Cell Movement; Cell Survival; Cell- and Tissue-Based Therapy; Cells, Cultured; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Female; Fibroblasts; Humans; Neural Stem Cells; Olfactory Mucosa; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Time Factors; Transfection; Transplantation, Autologous; Tyrosine 3-Monooxygenase | 2012 |
The role of central amygdala dopamine in disengagement behavior.
Topics: Amphetamine; Amygdala; Animals; Behavior, Animal; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Long-Evans; Substantia Nigra | 2013 |
The neuroprotective and neurorescue effects of carbamylated erythropoietin Fc fusion protein (CEPO-Fc) in a rat model of Parkinson's disease.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Corpus Striatum; Disease Models, Animal; Drug Administration Schedule; Erythropoietin; Female; Hematocrit; Hemoglobins; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Rotarod Performance Test; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2013 |
Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia.
Topics: Amantadine; Amphetamine; Animals; Apomorphine; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Medial Forebrain Bundle; Motor Activity; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Piperazines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Time Factors; Tyrosine 3-Monooxygenase | 2013 |
GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Functional Laterality; GABA-A Receptor Agonists; Homovanillic Acid; Male; Medial Forebrain Bundle; Mental Disorders; Muscimol; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Receptors, GABA-A; Statistics, Nonparametric; Subthalamic Nucleus; Time Factors | 2013 |
Amphetamine-induced dyskinesia in the transplanted hemi-Parkinsonian mouse.
Topics: Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Cell Transplantation; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Embryo, Mammalian; Functional Laterality; Levodopa; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Oxidopamine; Parkinson Disease; Stereotyped Behavior | 2012 |
Adult hemiparkinsonian rats do not benefit from tactile stimulation.
Topics: Adrenergic Agents; Amphetamine; Animals; Corpus Striatum; Dendrites; Disease Models, Animal; Functional Laterality; Gene Expression Regulation; Hippocampus; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Physical Stimulation; Prefrontal Cortex; Psychomotor Performance; Rats; Rats, Long-Evans; Time Factors; Touch | 2014 |
Nigral 6-hydroxydopamine lesion impairs performance in a lateralised choice reaction time task--impact of training and task parameters.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Choice Behavior; Cognition Disorders; Disease Models, Animal; Female; Functional Laterality; Oxidopamine; Psychomotor Performance; Rats; Reaction Time; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2014 |
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.
Topics: Adrenergic Agents; Adrenergic Neurons; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Benzylamines; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Levodopa; Motor Activity; Nerve Degeneration; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Stereotyped Behavior | 2014 |
Differential effects of intrastriatal 6-hydroxydopamine on cell number and morphology in midbrain dopaminergic subregions of the rat.
Topics: Amphetamine; Animals; Cell Count; Cell Nucleolus; Cell Shape; Cell Size; Central Nervous System Stimulants; Dopaminergic Neurons; Functional Laterality; Male; Mesencephalon; Motor Activity; Oxidopamine; Parkinsonian Disorders; Pars Compacta; Rats; Silver Compounds; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2014 |
Regenerative therapy in experimental parkinsonism: mixed population of differentiated mouse embryonic stem cells, rather than magnetically sorted and enriched dopaminergic cells provide neuroprotection.
Topics: Adrenergic Agents; Amphetamine; Animals; Apomorphine; Brain; Cell Differentiation; Disease Models, Animal; Dopamine; Embryonic Stem Cells; Functional Laterality; Magnetics; Male; Medial Forebrain Bundle; Nerve Tissue Proteins; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation | 2014 |
Unilateral olfactory deficit in a hemiparkinson's disease mouse model.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Corpus Striatum; Discrimination, Psychological; Disease Models, Animal; Functional Laterality; Immunohistochemistry; Male; Maze Learning; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Neuropsychological Tests; Olfactory Perception; Oxidopamine; Parkinsonian Disorders; Reward | 2014 |
A partial lesion model of Parkinson's disease in mice--characterization of a 6-OHDA-induced medial forebrain bundle lesion.
Topics: Amphetamine; Animals; Area Under Curve; Dopamine Agents; Dopaminergic Neurons; Dose-Response Relationship, Drug; Immunohistochemistry; Medial Forebrain Bundle; Membrane Glycoproteins; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Oxidopamine; Parkinsonian Disorders; Receptors, Interleukin-1; ROC Curve; Rotation; Severity of Illness Index | 2015 |
Interrogating the aged striatum: robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration.
Topics: Aging; Amphetamine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopaminergic Neurons; Dyskinesia, Drug-Induced; Embryo, Mammalian; Functional Laterality; Levodopa; Neurites; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; Recovery of Function; Stem Cell Transplantation; Substance P | 2015 |
Orbitofrontal or accumbens dopamine depletion does not affect risk-based decision making in rats.
Topics: Amphetamine; Animals; Cocaine; Decision Making; Dopamine; Dopamine Agents; Frontal Lobe; Male; Neuropsychological Tests; Nucleus Accumbens; Oxidopamine; Probability; Rats; Reward; Risk-Taking | 2015 |
Striatal tyrosine hydroxylase-positive neurons are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice.
Topics: Amphetamine; Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Functional Laterality; Levodopa; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Neurons; Oxidopamine; Parkinson Disease; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-fos; Serotonin Plasma Membrane Transport Proteins; Statistics, Nonparametric; Tyrosine 3-Monooxygenase | 2015 |
Chronic deep brain stimulation of the medial forebrain bundle reverses depressive-like behavior in a hemiparkinsonian rodent model.
Topics: Adrenergic Agents; Amphetamine; Animals; Central Nervous System Stimulants; Deep Brain Stimulation; Depressive Disorder; Disease Models, Animal; Female; Functional Laterality; Medial Forebrain Bundle; Movement; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Stress, Psychological; Swimming; Time Factors; Vocalization, Animal | 2015 |
Norepinephrine in prelimbic cortex delays extinction of amphetamine-induced conditioned place preference.
Topics: Amphetamine; Animals; Association Learning; Cues; Dopaminergic Neurons; Drug-Seeking Behavior; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Oxidopamine; Prefrontal Cortex | 2016 |
DopAmide: Novel, Water-Soluble, Slow-Release l-dihydroxyphenylalanine (l-DOPA) Precursor Moderates l-DOPA Conversion to Dopamine and Generates a Sustained Level of Dopamine at Dopaminergic Neurons.
Topics: Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Central Nervous System Stimulants; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Levodopa; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Rotation; Sympatholytics; Time Factors | 2016 |
Effect of the sonic hedgehog receptor smoothened on the survival and function of dopaminergic neurons.
Topics: Amphetamine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain-Derived Neurotrophic Factor; Cell Survival; Central Nervous System Stimulants; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Locomotion; Mice; Mice, Knockout; Nuclear Receptor Subfamily 4, Group A, Member 2; Oxidopamine; Smoothened Receptor; Substantia Nigra; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2016 |
Dopamine is Required for Activity-Dependent Amplification of Arc mRNA in Developing Postnatal Frontal Cortex.
Topics: Adrenergic Agents; Age Factors; AIDS-Related Complex; Amphetamine; Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Benzazepines; Dopamine; Dopamine Agents; Dopaminergic Neurons; Electroshock; Frontal Lobe; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Microarray Analysis; Oxidopamine; Receptors, Dopamine D1; RNA, Messenger; Ventral Tegmental Area | 2017 |
Developing therapeutically more efficient Neurturin variants for treatment of Parkinson's disease.
Topics: Amphetamine; Animals; CHO Cells; Cricetulus; Disease Models, Animal; Drug Design; Genetic Variation; Humans; Macaca fascicularis; Male; Models, Molecular; Neurturin; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-ret; Rats; Rats, Wistar; Stereotyped Behavior; Sympatholytics; Tyrosine 3-Monooxygenase | 2016 |
Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson's Disease.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Choline O-Acetyltransferase; Cholinergic Neurons; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Functional Laterality; Genotype; Hypokinesia; Levodopa; Luminescent Proteins; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Optogenetics; Oxidopamine; Parkinson Disease; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Transduction, Genetic | 2016 |
The significance of rotational behavior and sensitivity of striatal dopamine receptors in hemiparkinsonian rats: A comparative study of lactacystin and 6-OHDA.
Topics: Acetylcysteine; Amphetamine; Animals; Apomorphine; Benzazepines; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Functional Laterality; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Pars Compacta; Raclopride; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation | 2017 |
Transplantation site influences the phenotypic differentiation of dopamine neurons in ventral mesencephalic grafts in Parkinsonian rats.
Topics: Adrenergic Agents; Amphetamine; Animals; Brain Tissue Transplantation; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Embryo, Mammalian; Female; Male; Medial Forebrain Bundle; Neurogenesis; Oxidopamine; Parkinsonian Disorders; Pregnancy; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2017 |
Long-term protective effects of AAV9-mesencephalic astrocyte-derived neurotrophic factor gene transfer in parkinsonian rats.
Topics: Adenoviridae; Adrenergic Agents; Amphetamine; Animals; Cells, Cultured; Disease Models, Animal; Dopamine; Female; Gene Expression Regulation; Gene Transfer Techniques; Glial Cell Line-Derived Neurotrophic Factor; Humans; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neuroblastoma; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 2017 |
Differential behavioral outcomes following neonatal versus fetal human retinal pigment epithelial cell striatal implants in parkinsonian rats.
Topics: Amphetamine; Animals; Cell Survival; Cell Transplantation; Cellular Senescence; Central Nervous System Stimulants; Corpus Striatum; Epithelial Cells; Female; Humans; Infant, Newborn; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Random Allocation; Rats, Sprague-Dawley; Retinal Pigment Epithelium; Walking | 2017 |
Pirouetting pigs: A large non-primate animal model based on unilateral 6-hydroxydopamine lesioning of the nigrostriatal pathway.
Topics: Amphetamine; Animals; Apomorphine; Biophysics; Central Nervous System Stimulants; Corpus Striatum; Deep Brain Stimulation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Functional Laterality; Magnetic Resonance Imaging; Neural Pathways; Oxidopamine; Parkinsonian Disorders; Substantia Nigra; Swine; Swine, Miniature; Sympatholytics; Tyrosine 3-Monooxygenase | 2018 |
Behavioral and neurochemical responses derived from dopaminergic intrastriatal grafts in hemiparkinsonian rats engaged in a novel motor task.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Cell Differentiation; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Functional Laterality; LIM-Homeodomain Proteins; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Microdialysis; Oxidopamine; Parkinson Disease, Secondary; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase | 2018 |
Attenuated dopaminergic neurodegeneration and motor dysfunction in hemiparkinsonian mice lacking the α5 nicotinic acetylcholine receptor subunit.
Topics: Amphetamine; Animals; Antiparkinson Agents; Brain; Central Nervous System Stimulants; Dopamine; Dopaminergic Neurons; Dyskinesia, Drug-Induced; Female; Functional Laterality; Levodopa; Male; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurodegenerative Diseases; Oxidopamine; Parkinsonian Disorders; Receptors, Dopamine; Receptors, Nicotinic; RNA, Messenger | 2018 |
Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation.
Topics: Amphetamine; Animals; Antioxidants; Corpus Striatum; Dopamine; Dopamine Agents; Dopaminergic Neurons; Fatty Acids, Omega-3; Male; Motor Activity; Neuroglia; NF-E2-Related Factor 2; Oxidative Stress; Oxidopamine; Parkinson Disease; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2019 |
Implication of nigral dopaminergic lesion and repeated L-dopa exposure in neuropsychiatric symptoms of Parkinson's disease.
Topics: Amphetamine; Animals; Antiparkinson Agents; Anxiety; Benserazide; Disease Models, Animal; Dopamine; Forelimb; Gait Disorders, Neurologic; Interpersonal Relations; Levodopa; Locomotion; Male; Maze Learning; Memory Disorders; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 2019 |
The macrocyclic lactones ivermectin and moxidectin show differential effects on rotational behavior in the 6-hydroxydopamine mouse model of Parkinson's disease.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Disease Models, Animal; Female; Ivermectin; Macrolides; Male; Medial Forebrain Bundle; Mice, Inbred C57BL; Movement; Oxidopamine; Parkinson Disease | 2020 |
Antidepressant-Like Properties of Intrastriatal Botulinum Neurotoxin-A Injection in a Unilateral 6-OHDA Rat Model of Parkinson's Disease.
Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Botulinum Toxins, Type A; Corpus Striatum; Disease Models, Animal; Injections; Male; Motor Activity; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Rats; Rats, Wistar | 2021 |
High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease.
Topics: Amphetamine; Animals; Behavior, Animal; Blood-Brain Barrier; Corpus Striatum; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Dopaminergic Neurons; Insulin Resistance; Male; Mice; Microglia; Oxidopamine; Parkinson Disease, Secondary; Pericytes | 2021 |
Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson's Disease.
Topics: Amphetamine; Animals; Dopamine; Dopaminergic Neurons; Mice; Oxidopamine; Parkinson Disease; Rats | 2023 |