amphetamine has been researched along with fenfluramine in 171 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 131 (76.61) | 18.7374 |
1990's | 28 (16.37) | 18.2507 |
2000's | 4 (2.34) | 29.6817 |
2010's | 8 (4.68) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Glennon, RA | 1 |
Hoebel, BG | 2 |
Frey, HH | 1 |
Allan, D; Michell, RH | 1 |
Blundell, JE; Leshem, MB | 4 |
Meyerson, BJ; Michanek, A | 1 |
Beymer, CH; Quock, RM | 1 |
D'mello, GD; Stolerman, IP | 1 |
Bargalló, MA; Beascoa, E; Bermejo, P; Bruseghini, L; Giráldez, A | 1 |
Barrett, AM | 1 |
Comai, K; Sullivan, AC; Triscari, J | 1 |
Reuter, CJ | 1 |
Buczko, W; Garattini, S; Jori, A; Samanin, R | 1 |
Dobrzanski, S; Doggett, NS | 1 |
Ghosh, MN; Parvathy, S | 1 |
Hoebel, BG; Kornblith, CL | 1 |
Baran, L; Maj, J; Palider, W | 1 |
Counsell, RE; Lu, M; Tessel, RE; Woods, JH | 1 |
Basmadjian, GP; Counsell, RE; Tessel, RE; Woods, JH | 1 |
Bushing, JA; Sanders-Bush, E; Sulser, F | 1 |
Bowley, M; Brindley, DN | 1 |
Andersson, BE; Götestam, KG | 1 |
Silverstone, T | 3 |
Young, R | 1 |
Clark, AJ; Clark, JM; Winn, P | 1 |
Goudie, AJ | 1 |
Olds, ME; Yuwiler, A | 1 |
Evans, SM; Johanson, CE; Zacny, JP | 1 |
Blackburn, TP; Cox, B; Pearce, RJ; Thornber, CW | 1 |
Rayport, S; Sulzer, D | 1 |
MacKenzie-Taylor, D; Rech, RH; Shukla, R | 1 |
Schechter, MD | 1 |
Cooper, SJ | 1 |
Leibowitz, SF; Shor-Posner, G | 1 |
Sugrue, MF | 1 |
Bendotti, C; Garattini, S; Samanin, R | 1 |
Orthen-Gambill, N | 1 |
Levitsky, DA; Strupp, BJ | 1 |
Oslan, IA; Thompson, GB; Wolgin, DL | 1 |
Donnelly, M; Ismond, DR; Rapoport, JL | 1 |
Blundell, JE | 2 |
Angel, I; Crawley, JN; Paul, SM; Stivers, JA | 1 |
Akintonwa, DA | 1 |
Hunsinger, RN; Kibbe, AH; Wilson, MC | 1 |
Finkelstein, JA; Schechter, MD | 1 |
Knoll, J; Sándor, G | 1 |
Fibiger, HC; McGeer, EG; Zis, AP | 1 |
Jespersen, S; Scheel-Krüger, J | 1 |
Dolfini, E; Garattini, S; Jori, A; Tognoni, G | 1 |
Beckett, AH; Coutts, RT; Ogunbona, FA | 2 |
Fuller, RW; Molloy, BB; Snoddy, HD | 1 |
Corson, J; Haider, I; Oswald, I; Riley, I | 1 |
Gallager, DA; Sanders-Bush, E; Sulser, F | 1 |
Knapp, S; Mandell, AJ | 1 |
Firth, H; Lewis, SA; Ogunremi, OO; Oswald, I | 1 |
Bizzi, A; Marsh, JB | 1 |
Beckett, AH; Triggs, EJ | 1 |
Bernardi, D; Jori, A | 1 |
Bonaccorsi, A; Jespersen, J | 1 |
Beckett, AH; Moffat, AC | 1 |
Mayer, SR; Southgate, PJ; Wilson, AB | 1 |
Beckett, AH; Brookes, LG | 1 |
Leibowitz, SF | 1 |
Hoyer, I; Van Zwieten, PA | 1 |
Babulova, A; Bonaccorsi, A; Cotillo, P; Podvalova, I | 1 |
Clineschmidt, BV; Mcguffin, JC; Werner, AB | 1 |
Dolfini, E; Jori, A | 1 |
Sapeika, N | 1 |
Kirby, MJ; Turner, P | 1 |
Cattabeni, F; Paoletti, R; Racagni, G | 1 |
Götestam, KG; Gunne, LM | 1 |
Bentwich, T; Bentwich, Z | 1 |
Court, JM | 1 |
Duhault, J | 1 |
Protiva, M | 1 |
Sheard, MH | 1 |
Hutchins, DA; Rogers, KJ | 1 |
Garattini, S; Ghezzi, D; Samanin, R; Valzelli, L | 1 |
Laurent, LP | 1 |
Levin, A | 1 |
Everitt, BJ; Hacket, NB; Rand, MJ | 1 |
Bizzi, A; Garattini, S; Hess, ME; Tacconi, MT; Veneroni, E | 1 |
Rosecrans, JA; Schechter, MD | 1 |
Berger, HJ; Brown, CC; Krantz, JC | 1 |
Garattini, S | 1 |
Wesley-Hadzija, B | 1 |
Locket, S | 1 |
Goudie, AJ; Taylor, M; Williams, A | 1 |
Pardo, EG; Vidrio, H | 1 |
Johnson, SA; Maickel, RP | 1 |
Munro, JF | 1 |
Geyer, MA; Knapp, S; Mandell, AJ | 1 |
Sedgwick, JP | 2 |
Sachweh, H | 1 |
Bernier, A; Le Douarec, JC; Sicot, N | 1 |
Kirch, JD; Tang, AH | 1 |
Rutledge, CO; Ziance, RJ | 1 |
Cattabeni, F; Costa, E; Morgan, CD | 1 |
Azzaro, AJ; Rutledge, CO; Ziance, RJ | 1 |
Offermeier, J; Potgieter, B | 1 |
Cox, RH; Maickel, RP | 1 |
Kemper, F | 1 |
Lawlor, RB; Yelnosky, J | 1 |
Funderburk, WH; Johnson, DN; Ward, JW | 1 |
Moormann, J; Opitz, K | 1 |
De Groot, JC | 1 |
Bruce, RB; Maynard, WR | 1 |
Duhault, J; Fenard, S | 1 |
Laubie, M; Le Douarec, JC; Schmitt, H | 1 |
Kirby, MJ; Pleece, SA; Redfern, PH | 1 |
Blundell, JE; Latham, CJ; Rogers, PJ; Tombros, E | 1 |
Koek, W; Slangen, JL | 1 |
Farquhar, DL; Galloway, SM; Munro, JF | 1 |
Feldman, RS; McElroy, JF | 1 |
Morris, RG; Reece, PA | 1 |
Bhargava, HN; Gray, NM; Lu, MC | 3 |
Leshem, M | 2 |
Dalló, J; Knoll, J; Yen, TT | 1 |
Clark, WG; Clark, YL | 1 |
Bunting, PR; Clineschmidt, BV | 1 |
Kanarek, RB; Orthen-Gambill, N | 1 |
Liang, NY; Rutledge, CO | 1 |
Fahim, AT; Hamdy, MA | 1 |
Knoll, J; Timár, J | 1 |
Bermann, MC; Berthelot, P; Bonte, JP; Brunet, C; Cazin, JC; Cazin, M; Debaert, M; Lesieur, D; Lesieur, I; Luyckx, M | 1 |
Beregi, L; Duhault, J; Roman, F | 1 |
Levitsky, DA; Lupoli, J; Strupp, BJ | 1 |
Blundell, JE; Latham, CJ | 1 |
Olds, ME | 1 |
López Cabrera, M; Valencia Flores, M; Velázquez Martínez, DN; Villarreal, JE | 1 |
Fisher, H; Goldberg, M; Mirovsky, Y; Sekowski, A; Wagner, GC; Yu, YL | 1 |
Anderer, P; Barbanoj, MJ; Grünberger, J; Saletu, B; Sieghart, W | 1 |
Barbanoj, MJ; Grünberger, J; Linzmayer, L; Saletu, B | 1 |
Corwin, RL; Schuster, CR | 1 |
Bennett, BA; Hollingsworth, CK; Wichems, CH | 1 |
Feeney, S; Goodall, E; Silverstone, T | 1 |
Fletcher, PJ | 1 |
Miles, C; Parker, LA; Siegel, S; Turenne, SD | 1 |
Balster, RL; Levesque, TR; Locke, KW; Nicholson, KL | 1 |
Baumann, MH; Goldberg, SR; Rothman, RB; Schindler, CW; Shoaib, M | 1 |
Crespi, D; Gobbi, M; Mennini, T | 1 |
Dafters, RI; Lynch, E | 1 |
Glennon, RA; Young, R | 1 |
Fisher, H; Halladay, AK; Hsu, T; Sekowski, A; Wagner, GC | 1 |
Campbell, TC; King, JM; Levitsky, DA; Lin, X | 1 |
Hara, K; Imamura, T; Kojima, T; Liu, J; Namera, A; Okajima, K; Yashiki, M | 1 |
Ayestas, MA; Baumann, MH; Brockington, A; Dersch, CM; Rice, KC; Rothman, RB | 1 |
Giambalvo, CT; Price, LH | 1 |
Amos-Kroohs, R; Braun, AA; Grace, CE; Graham, DL; He, E; Schaefer, TL; Skelton, MR; Vorhees, CV; Williams, MT | 1 |
Bonhaus, DW; McFarland, K; Price, DL | 1 |
Banks, ML; Bauer, CT; Blough, BE; Negus, SS | 1 |
Calipari, ES; Ferris, MJ; Jones, SR; Siciliano, CA | 1 |
Balderas, I; Bonci, A; Britt, JP; Chung, SL; Harvey, BK; Marino, RAM; McDevitt, RA; Richie, CT; Shen, H; Tiran-Cappello, A | 1 |
Banks, ML; Glennon, RA; Kolanos, R; Lazenka, MF; Negus, SS; Sakloth, F; Suyama, JA | 1 |
Banks, ML; Negus, SS | 1 |
21 review(s) available for amphetamine and fenfluramine
Article | Year |
---|---|
Pharmacologic control of feeding.
Topics: Amphetamine; Animals; Brain Chemistry; Dopamine; Eating; Fenfluramine; Glucose; Humans; In Vitro Techniques; Norepinephrine; Phenylpropanolamine; Rats; Serotonin; Sympathomimetics; Time Factors | 1977 |
A review of the CNS effects of fenfluramine, 780SE and norfenfluramine on animals and man.
Topics: Acetylcholine; Amphetamine; Analgesia; Animals; Behavior; Biogenic Amines; Body Temperature Regulation; Brain; Clomipramine; Depression; Drinking; Eating; Fenfluramine; Hormones; Humans; Indoles; Norfenfluramine; Sleep | 1975 |
The mechanism of action of fenfluramine.
Topics: Amphetamine; Animals; Appetite; Biogenic Amines; Blood Platelets; Brain; Corpus Striatum; Dopamine; Eating; Fenfluramine; Humans; Indoles; Mice; Proadifen; Rats; Serotonin | 1975 |
Drugs, appetite and obesity: a personal odyssey.
Topics: Amphetamine; Animals; Eating; Fenfluramine; Humans; Hunger; Obesity | 1992 |
Discriminative stimulus properties of amphetamine, cathinone, and related agents.
Topics: Alkaloids; Amphetamine; Animals; Central Nervous System Stimulants; Cues; Discrimination Learning; Dopamine; Fenfluramine; Generalization, Stimulus; Humans; Norepinephrine | 1991 |
Brain serotonin and eating behavior.
Topics: Amphetamine; Animals; Brain; Brain Mapping; Corticosterone; Feeding Behavior; Fenfluramine; Food Preferences; Hypothalamic Area, Lateral; Hypothalamus, Middle; Insulin; Neural Inhibition; Neurotransmitter Agents; Paraventricular Hypothalamic Nucleus; Rats; Receptors, Adrenergic, alpha; Satiety Response; Serotonin | 1986 |
Neuropharmacology of drugs affecting food intake.
Topics: Amphetamine; Animals; Appetite Depressants; Brain Chemistry; Dopamine; Feeding Behavior; Fenfluramine; gamma-Aminobutyric Acid; Neurotransmitter Agents; Norepinephrine; Serotonin | 1987 |
Direct and indirect thermogenic effects of anorectic drugs.
Topics: Adipose Tissue, Brown; Amphetamine; Animals; Appetite Depressants; Body Temperature Regulation; Body Weight; Energy Metabolism; Ephedrine; Fenfluramine; Humans; Sodium-Potassium-Exchanging ATPase | 1985 |
Serotonin manipulations and the structure of feeding behaviour.
Topics: Amphetamine; Animals; Appetite; Brain; Conditioning, Operant; Feeding Behavior; Fenfluramine; Food Preferences; Humans; Neural Pathways; Obesity; Rats; Satiety Response; Serotonin | 1986 |
[Obesity-background and treatment].
Topics: Age Factors; Amphetamine; Appetite Regulation; Body Weight; Diet, Reducing; Fatty Acids; Female; Fenfluramine; Glycerophosphates; Humans; Lipid Metabolism; Male; Obesity; Physical Fitness; Sex Factors; Social Conformity | 1972 |
The management of obesity.
Topics: Adolescent; Adult; Amphetamine; Body Weight; Child; Chlorphentermine; Diet, Reducing; Diethylpropion; Fenfluramine; Humans; Monoamine Oxidase Inhibitors; Obesity; Phentermine; Starvation | 1972 |
[Pharmacology and biochemistry of fenfluramine].
Topics: Amphetamine; Animals; Appetite; Body Temperature Regulation; Cats; Central Nervous System; Depression, Chemical; Dogs; Drug Interactions; Fatty Acids, Nonesterified; Fenfluramine; Humans; Hypothalamus; Mice; Obesity; Rabbits; Rats; Serotonin; Sleep; Triglycerides | 1973 |
Psychopharmacological news in the year 1971 from the viewpoint of a medicinal chemist.
Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Antiparkinson Agents; Biotransformation; Cannabis; Chemistry, Pharmaceutical; Fenfluramine; Hallucinogens; Humans; Lysergic Acid Diethylamide; Nortriptyline; Psychopharmacology; Research; Structure-Activity Relationship; Tranquilizing Agents | 1973 |
New thoughts on obesity and its treatment.
Topics: Amphetamine; Diet, Reducing; Dietary Carbohydrates; Dietary Fats; Fenfluramine; Humans; Lipid Metabolism, Inborn Errors; Obesity; Thyroxine | 1968 |
[Anorexics. 25].
Topics: Amphetamine; Appetite Depressants; Chemical Phenomena; Chemistry; Chlorphentermine; Ephedrine; Fenfluramine; Humans; Morpholines; Phentermine | 1968 |
Obesity--the health hazard of our time.
Topics: Amphetamine; Appetite Depressants; Chorionic Gonadotropin; Diet, Reducing; Fasting; Fenfluramine; Fluorenes; Glucose; Humans; Lipid Mobilization; Methylcellulose; Obesity; Phenethylamines; Skinfold Thickness; Thyroid Hormones | 1971 |
The clinical pharmacology of appetite--its relevance to psychiatry.
Topics: Amphetamine; Anorexia; Appetite; Bipolar Disorder; Brain Chemistry; Depressive Disorder; Dopamine; Fenfluramine; Humans; Psychiatry; Psychotropic Drugs; Serotonin | 1983 |
The current status of antiobesity drugs.
Topics: Adult; Amphetamine; Appetite Depressants; Body Weight; Child; Diethylpropion; Dose-Response Relationship, Drug; Female; Fenfluramine; Humans; Mazindol; Obesity; Phentermine | 1984 |
Psychopharmacology of hunger and food intake in humans.
Topics: Amitriptyline; Amphetamine; Appetite Depressants; Chlorpromazine; Cholecystokinin; Cyproheptadine; Eating; Feeding Behavior; Fenfluramine; Humans; Hunger; Insulin; Lithium; Naloxone | 1982 |
Changes in body temperature after administration of adrenergic and serotonergic agents and related drugs including antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents; Biogenic Amines; Body Temperature; Fenfluramine; Humans; Methylphenidate; Quipazine; Serotonin; Serotonin Antagonists; Sympathomimetics; Tryptamines | 1980 |
Differential effects of pharmacological agents acting on monoaminergic systems on drug-induced anorexia.
Topics: Amphetamine; Animals; Appetite Depressants; Dogs; Dopamine Antagonists; Fenfluramine; Hydroxydopamines; Metergoline; Methysergide; Mice; Norepinephrine; Raphe Nuclei; Rats; Serotonin Antagonists | 1980 |
6 trial(s) available for amphetamine and fenfluramine
Article | Year |
---|---|
Fenfluramine treatment of childhood attention deficit disorder with hyperactivity: a preliminary report.
Topics: Amphetamine; Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; Double-Blind Method; Fenfluramine; Humans; Male; Psychiatric Status Rating Scales; Random Allocation | 1986 |
The effect of acute administration of (meta trifluoro methyl-phenyl)-1-(benzoyl oxy) ethyl amino-2-propane (780 SE) and fenfluramine on human sleep.
Topics: Adult; Amphetamine; Appetite Depressants; Fenfluramine; Fluorine; Humans; Male; Phenethylamines; Propylamines; Sleep; Sleep Stages; Sleep, REM | 1970 |
Subjective effects of two anorexigenic agents fenfluramine and AN 448 in amphetamine-dependent subjects.
Topics: Adult; Amphetamine; Appetite Depressants; Fenfluramine; Humans; Imidazoles; Male; Substance-Related Disorders | 1972 |
Clinical-pharmacological study with the two isomers (d-, l-) of fenfluramine and its comparison with chlorpromazine and d-amphetamine: blood levels, EEG mapping and safety evaluation.
Topics: Adult; Amphetamine; Analysis of Variance; Biological Availability; Brain; Brain Mapping; Chlorpromazine; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Female; Fenfluramine; Hemodynamics; Humans; Male; Prolactin; Spleen; Stereoisomerism | 1993 |
Clinical-pharmacological study with the two isomers (d-, l-) of fenfluramine and its comparison with chlorpromazine and d-amphetamine: psychometric and psychophysiological evaluation.
Topics: Adult; Amphetamine; Analysis of Variance; Autonomic Nervous System; Behavior; Chlorpromazine; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fenfluramine; Humans; Male; Mental Processes; Psychometrics; Psychomotor Performance; Psychotropic Drugs; Stereoisomerism; Thymus Gland | 1993 |
The effects of D- and L-fenfluramine (and their interactions with D-amphetamine) on psychomotor function and mood.
Topics: Adult; Affect; Amphetamine; Appetite; Central Nervous System Stimulants; Double-Blind Method; Fenfluramine; Humans; Male; Psychomotor Performance; Selective Serotonin Reuptake Inhibitors; Stereoisomerism | 1996 |
144 other study(ies) available for amphetamine and fenfluramine
Article | Year |
---|---|
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin | 2017 |
Three anorectic drugs: similar structures but different effects on brain and behavior.
Topics: Amphetamine; Animals; Appetite Depressants; Behavior; Blood Glucose; Body Weight; Brain; Dose-Response Relationship, Drug; Eating; Fenfluramine; Haplorhini; Humans; Hypothalamus; Mesencephalon; Models, Neurological; Obesity; Phenylpropanolamine; Rats; Receptors, Adrenergic; Self Stimulation | 1978 |
Hyperthermia induced by amphetamine, p-chloroamphetamine and fenfluramine in the rat-1.
Topics: Amphetamine; Amphetamines; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Body Temperature; Clomipramine; Cyproheptadine; Depression, Chemical; Disulfiram; Dopamine; Female; Fenclonine; Fenfluramine; Haloperidol; Hypothalamus; Methyltyrosines; p-Chloroamphetamine; Rats; Serotonin; Stimulation, Chemical; Time Factors | 1975 |
Central tryptaminergic mediation of the hyperthermia induced by amphetamine and halogenated analogues of it?
Topics: Amphetamine; Amphetamines; Animals; Body Temperature; Cyproheptadine; Disulfiram; Drug Interactions; Fenclonine; Fenfluramine; Hypothalamus; Methyltyrosines; p-Chloroamphetamine; Rats; Serotonin; Stimulation, Chemical; Tryptamines | 1975 |
Enhanced synthesis de novo of phosphatidylinositol in lymphocytes treated with cationic amphiphilic drugs.
Topics: Amphetamine; Animals; Cetrimonium Compounds; Chlorpromazine; Cocaine; Dibucaine; Dose-Response Relationship, Drug; Fenfluramine; Imipramine; Lectins; Lymphocytes; Phenethylamines; Phosphatidylinositols; Procaine; Promethazine; Swine; Time Factors; Trifluoperazine | 1975 |
The effect of 5-hydroxytryptophan on food intake and on the anorexic action of amphetamine and fenfluramine.
Topics: 5-Hydroxytryptophan; Amphetamine; Analysis of Variance; Animals; Appetite; Body Weight; Brain; Fenfluramine; Hypothalamus; Male; Rats; Time Factors | 1975 |
A comparative study of different amphetamines on copulatory behavior and stereotype activity in the female rat.
Topics: Amphetamine; Amphetamines; Animals; Behavior; Copulation; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Fenfluramine; Humans; Motor Activity; p-Chloroamphetamine; Pimozide; Rats; Receptors, Dopamine; Stereotyped Behavior; Time Factors | 1977 |
Molindone: an apomorphine antagonist in the rabbit.
Topics: Amphetamine; Animals; Apomorphine; Body Temperature; Fenfluramine; Indoles; Lysergic Acid Diethylamide; Male; Models, Biological; Molindone; Rabbits; Time Factors | 1977 |
Amphetamine-induced hypodipsia and its implications for conditioned taste aversion in rats.
Topics: Amphetamine; Amphetamines; Animals; Avoidance Learning; Chlorphentermine; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Drinking; Fenfluramine; Male; Rats; Taste | 1978 |
[Pharmacology of ITA 213, a producer of anorexic activity].
Topics: Amphetamine; Animals; Appetite Depressants; Central Nervous System; Fenfluramine; Isoindoles; Rats | 1978 |
Neuropharmacology of appetite regulation.
Topics: Amphetamine; Animals; Appetite Depressants; Appetite Regulation; Catecholamines; Fenfluramine; Humans; Hypothalamus; Models, Biological; Rats; Serotonin; Serotonin Antagonists | 1978 |
Comparative effects of amphetamine and fenfluramine on lipid biosynthesis and absorption in the rat.
Topics: Adipose Tissue; Amphetamine; Animals; Cholesterol; Fatty Acids; Female; Fenfluramine; In Vitro Techniques; Intestinal Absorption; Lipase; Lipid Metabolism; Lipids; Liver; Pancreas; Rats; Triglycerides | 1978 |
The effects of (+)-amphetamine and fenfluramine on feeding in starved and satiated mice.
Topics: Amphetamine; Animals; Arousal; Caffeine; Circadian Rhythm; Dose-Response Relationship, Drug; Feeding Behavior; Fenfluramine; Male; Mice; Satiation; Starvation | 1976 |
Tolerance pattern of the anorexigenic action of amphetamines, fenfluramine, phenmetrazine and diethylpropion in rats.
Topics: Amphetamine; Animals; Appetite Depressants; Body Weight; Diethylpropion; Drinking; Drug Tolerance; Eating; Fenfluramine; Male; Phenmetrazine; Rats; Time Factors | 1976 |
A dose-response study of anorectic drug effects on food intake, self-stimulation, and stimulation-escape.
Topics: Amphetamine; Animals; Brain; Dose-Response Relationship, Drug; Escape Reaction; Feeding Behavior; Fenfluramine; Male; Phenylpropanolamine; Rats; Self Stimulation; Time Factors | 1976 |
The effects of serotonergic and antiserotonergic drugs on the flexor reflex of spinal rat: a proposed model to evaluate the action on the central serotonin receptor.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anthracenes; Clonidine; Cyproheptadine; Decerebrate State; Fenfluramine; Hindlimb; Lysergic Acid Diethylamide; Male; Metergoline; Muscle Contraction; p-Chloroamphetamine; Piperidines; Rats; Reflex; Serotonin; Tryptophan | 1976 |
Structure-activity relationships between meta-substituted N-ethylamphetamines and locomotor activity in mice.
Topics: Amphetamine; Amphetamines; Animals; Fenfluramine; Male; Methyltyrosines; Mice; Motor Activity; Pargyline; Regression Analysis; Reserpine; Stimulation, Chemical; Structure-Activity Relationship | 1975 |
Structure-activity relationships between meta-substituted N-ethylamphetamines and isolated guinea-pig atrial rate.
Topics: Amphetamine; Amphetamines; Animals; Fenfluramine; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Pargyline; Regression Analysis; Reserpine; Stimulation, Chemical; Structure-Activity Relationship | 1975 |
Long-term effects of p-chloroamphetamine and related drugs on central serotonergic mechanisms.
Topics: Amphetamine; Amphetamines; Animals; Brain; Brain Chemistry; Chlorine; Dopamine; Dopamine Antagonists; Fenfluramine; In Vitro Techniques; Kinetics; Male; Methamphetamine; Norepinephrine; Rats; Serotonin; Synaptosomes; Tritium; Tryptophan Hydroxylase | 1975 |
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine, mepyramine and some of their derivatives.
Topics: Amphetamine; Animals; Chlorpromazine; Clofenapate; Clofibrate; Dibucaine; Fenfluramine; Glycerides; Glycerol-3-Phosphate O-Acyltransferase; Halofenate; Imipramine; In Vitro Techniques; Kinetics; Liver; Pharmacology; Phospholipids; Pyrilamine; Rats | 1975 |
Hypothalamic lesions and drug-induced anorexia.
Topics: Amphetamine; Animals; Appetite; Eating; Fenfluramine; Hypothalamus; Male; Norfenfluramine; Rats; Serotonin | 1975 |
Assessment of reinforcing properties of amphetamine analogues in self-administering rats.
Topics: Amphetamine; Animals; Behavior, Animal; Diethylpropion; Fenfluramine; Humans; Male; Phenmetrazine; Rats; Reinforcement, Psychology; Substance-Related Disorders | 1975 |
Aminorex produces stimulus effects similar to amphetamine and unlike those of fenfluramine.
Topics: Aminorex; Amphetamine; Animals; Central Nervous System Stimulants; Conditioning, Operant; Designer Drugs; Fenfluramine; Male; Rats; Rats, Inbred Strains; Reinforcement Schedule; Structure-Activity Relationship | 1992 |
N-methyl-D-aspartate lesions of the lateral hypothalamus do not reduce amphetamine or fenfluramine anorexia but enhance the acquisition of eating in response to tail pinch in the rat.
Topics: Amphetamine; Analysis of Variance; Animals; Anorexia; Feeding Behavior; Fenfluramine; Hypothalamic Area, Lateral; Male; N-Methylaspartate; Rats; Tail; Time Factors | 1992 |
Effects of acute and chronic fenfluramine on self-stimulation and its facilitation by amphetamine.
Topics: Amphetamine; Animals; Biogenic Monoamines; Brain Chemistry; Dopamine Antagonists; Drug Interactions; Electrodes, Implanted; Fenfluramine; Male; Rats; Rats, Sprague-Dawley; Self Stimulation; Serotonin; Serotonin Antagonists; Time Factors | 1992 |
Three-choice discrimination among (+)-amphetamine, fenfluramine and saline in pigeons.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Columbidae; Discrimination, Psychological; Female; Fenfluramine; Generalization, Stimulus; N-Methyl-3,4-methylenedioxyamphetamine; Sodium Chloride | 1990 |
Pharmacological studies in vivo with ICI 169,369, a chemically novel 5-HT2/5-HT1C receptor antagonist.
Topics: Amphetamine; Animals; Behavior, Animal; Blood Pressure; Body Temperature; Decerebrate State; Dogs; Female; Fenfluramine; Guinea Pigs; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Oxotremorine; Quinolines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Serotonin; Salivation; Serotonin; Serotonin Antagonists; Stereotyped Behavior | 1990 |
Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action.
Topics: Amphetamine; Animals; Cells, Cultured; Chromaffin Granules; Cocaine; Dopamine; Fenfluramine; Hydrogen-Ion Concentration; Imipramine; Immunoenzyme Techniques; Mesencephalon; Microscopy, Electron; Neurons; Phencyclidine; Psychotropic Drugs; Rats; Serotonin; Tyramine | 1990 |
Evidence for 5-HT2 receptor mediation in quipazine anorexia.
Topics: Amphetamine; Animals; Appetite Depressants; Eating; Fenfluramine; Male; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1990 |
Comparison of anorectic drugs in rats trained to discriminate between satiation and deprivation.
Topics: Amphetamine; Analysis of Variance; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Fenfluramine; Food Deprivation; Male; Norfenfluramine; Rats; Rats, Inbred Strains; Satiation | 1990 |
Pharmacological manipulations of sucrose consumption in the Syrian hamster.
Topics: Amphetamine; Animals; Benzodiazepines; Clonidine; Cricetinae; Feeding Behavior; Fenfluramine; Male; Mesocricetus; Sucrose; Tetrahydronaphthalenes; Thiophenes | 1989 |
Eating caused by neuropeptide-Y injection in the paraventricular hypothalamus: response to (+)-fenfluramine and (+)-amphetamine in rats.
Topics: Amphetamine; Animals; Feeding Behavior; Female; Fenfluramine; Hypothalamus; Male; Neuropeptide Y; Rats; Rats, Inbred Strains; Starvation | 1987 |
Sucrose intake unaffected by fenfluramine but suppressed by amphetamine administration.
Topics: Amphetamine; Animals; Blood Glucose; Dietary Carbohydrates; Dietary Proteins; Dose-Response Relationship, Drug; Energy Intake; Fenfluramine; Male; Rats; Sucrose; Synaptic Transmission | 1985 |
Effects of "anorexia" on appetitive and consummatory behavior.
Topics: Amphetamine; Animals; Anorexia; Appetite; Feeding and Eating Disorders; Feeding Behavior; Fenfluramine; Male; Motor Activity; Quinine; Rats; Rats, Inbred Strains; Saccharin | 1988 |
Site of action of anorectic drugs: glucoprivic- versus food deprivation-induced feeding.
Topics: Amphetamine; Animals; Appetite Depressants; Deoxy Sugars; Deoxyglucose; Eating; Fenfluramine; Food Deprivation; Hypothalamus; Male; Mazindol; Propranolol; Rats; Rats, Inbred Strains | 1987 |
Mechanistic biotransformations of some amphetamine drugs.
Topics: Amphetamine; Amphetamines; Animals; Benzphetamine; Biotransformation; Carcinogens; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Fenfluramine; Free Radicals; Mice; Oxygenases; Rats | 1986 |
The effect of previous d-amphetamine treatment on the disposition and lethality of fenfluramine in the rat.
Topics: Amphetamine; Animals; Body Weight; Drug Interactions; Fenfluramine; Half-Life; Injections, Intraperitoneal; Kinetics; Lethal Dose 50; Male; Rats; Rats, Inbred Strains; Tissue Distribution | 1985 |
Effect of dopamine agonists and fenfluramine on discriminative behavior in obese and lean Zucker rats.
Topics: Amphetamine; Animals; Appetite Depressants; Cocaine; Conditioning, Operant; Dextroamphetamine; Discrimination Learning; Dopamine Antagonists; Female; Fenfluramine; Obesity; Rats; Rats, Zucker | 1985 |
The time-structure of the anorectic effect of satietin.
Topics: Amphetamine; Animals; Appetite Depressants; Calcitonin; Feeding Behavior; Fenfluramine; Glycopeptides; Male; Rats; Rats, Inbred Strains | 1985 |
Feeding and drinking deficits after 6-hydroxydopamine administration in the rat: similarities to the lateral hypothalamic syndrome.
Topics: Amphetamine; Animals; Catecholamines; Corpus Striatum; Disease Models, Animal; Drinking Behavior; Feeding and Eating Disorders; Feeding Behavior; Fenfluramine; Humans; Hydroxydopamines; Hypothalamus; Male; Mesencephalon; Quinine; Rats; Substantia Nigra; Tranylcypromine; Tyrosine 3-Monooxygenase; Water-Electrolyte Balance | 1973 |
Evidence for a difference in mechanism of action between fenfluramine- and amphetamine-induced anorexia.
Topics: Amphetamine; Animals; Appetite Depressants; Dibenzazepines; Feeding Behavior; Female; Fenfluramine; Methylergonovine; Methysergide; Neurons; Rats; Serotonin; Serotonin Antagonists | 1973 |
Differential effects of amphetamine, fenfluramine and norfenfluramine stereoisomers on the increase of striatum homovanillic acid in rats.
Topics: Amphetamine; Animals; Basal Ganglia; Brain Chemistry; Corpus Striatum; Female; Fenfluramine; Fluorine; Homovanillic Acid; Hydrocarbons, Halogenated; Phenethylamines; Phenylacetates; Rats; Stereoisomerism | 1973 |
Metabolism of amphetamines. Identification of N-oxygenated products by gas chromatography and mass spectrometry.
Topics: Amphetamine; Chromatography, Gas; Fenfluramine; Hydroxylamines; Mass Spectrometry; Methods; Oxidation-Reduction; Oximes | 1973 |
Letter: Effect of some lipid-soluble derivatives of amphetamine on amphetamine levels in rat brain.
Topics: Amphetamine; Animals; Brain Chemistry; Chlorine; Fenfluramine; Fluorine; Liver; Male; Rats; Tritium | 1973 |
The structure of nitrones derived from amphetamines.
Topics: Amphetamine; Chemical Phenomena; Chemistry; Chromatography, Gas; Fenfluramine; Isomerism; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Molecular Conformation; Nitrogen Oxides; Oxidation-Reduction | 1974 |
Fenfluramine overdosage.
Topics: Adolescent; Amphetamine; Appetite Depressants; Female; Fenfluramine; Fluorine; Humans; Phenethylamines | 1969 |
On the mechanism of brain 5-hydroxytryptamine depletion by p-chloroamphetamine and related drugs and the specificity of their action.
Topics: Amphetamine; Animals; Brain; Brain Chemistry; Carbon Radioisotopes; Catecholamines; Chlorine; Fenclonine; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; Hypnotics and Sedatives; Methamphetamine; Neurons; Serotonin; Serotonin Antagonists; Synaptosomes; Time Factors; Tritium; Tryptophan Hydroxylase | 1974 |
Regulation of function of tryptophan hydroxylase.
Topics: Amphetamine; Amphetamines; Animals; Brain; Carbon Radioisotopes; Caudate Nucleus; Dextroamphetamine; Fenclonine; Fenfluramine; Kinetics; Lithium; Mesencephalon; Methamphetamine; Mixed Function Oxygenases; Morphine; Rats; Reserpine; Septum Pellucidum; Serotonin; Subcellular Fractions; Synaptosomes; Tryptophan Hydroxylase | 1974 |
Effects of amphetamine and fenfluramine on the net release of triglycerides of very low density lipoproteins by slices of rat liver.
Topics: Amphetamine; Animals; Fasting; Fatty Acids, Nonesterified; Fenfluramine; Lipoproteins; Lipoproteins, VLDL; Liver; Liver Glycogen; Male; Norepinephrine; Perfusion; Phospholipids; Rats; Serum Albumin; Triglycerides | 1972 |
Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes.
Topics: Adult; Amines; Amphetamine; Appetite Depressants; Benzphetamine; Biological Transport; Chlorpheniramine; Chlorphentermine; Ephedrine; Fenfluramine; Furans; Humans; Hydrogen-Ion Concentration; Lidocaine; Male; Membranes; Meperidine; Mephentermine; Methadone; Models, Biological; Morpholines; Mouth; Nicotine; Phenethylamines; Phenmetrazine; Phenylpropanolamine | 1967 |
Effect of amphetamine and amphetamine-like drugs on homovanillic acid concentration in the brain.
Topics: Amphetamine; Animals; Appetite Depressants; Body Temperature; Brain Chemistry; Feeding Behavior; Female; Fenfluramine; Mice; Phenylacetates; Rats | 1969 |
Anti-amphetamine activity of fenfluramine and S 992 in the isolated tail artery of the rat.
Topics: Amphetamine; Animals; Appetite Depressants; Arteries; Fenfluramine; Fluorine; In Vitro Techniques; Norepinephrine; Phenethylamines; Rats; Tail; Tetrabenazine; Vasoconstrictor Agents | 1969 |
Correlation of partition coefficients in n-heptane-aqueous systems with buccal absorption data for a series of amines and acids.
Topics: Absorption; Acids; Alkanes; Amphetamine; Benzoates; Chromatography, Gas; Cinnamates; Fenfluramine; Hydrogen-Ion Concentration; Molecular Weight; Mouth Mucosa; Solubility; Valerates | 1969 |
Central nervous system stimulant action of fenfluramine in rabbits.
Topics: Amphetamine; Animals; Central Nervous System; Cerebral Cortex; Electrodes, Implanted; Electroencephalography; Fenfluramine; Male; Pentobarbital; Rabbits; Stimulation, Chemical | 1970 |
Administration of two or more related drugs to investigate the effect of molecular modification and formulation on drug absorption, metabolism and excretion.
Topics: Adult; Amphetamine; Chlorphentermine; Chromatography, Gas; Fenfluramine; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Middle Aged; Phentermine; Structure-Activity Relationship; Time Factors; Urine | 1971 |
Central adrenergic receptors and the regulation of hunger and thirst.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amphetamine; Animals; Anorexia Nervosa; Chlorpromazine; Drinking Behavior; Epinephrine; Feeding Behavior; Fenfluramine; Humans; Hunger; Hypothalamus; Isoproterenol; Motivation; Norepinephrine; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Drug; Sotalol; Thirst | 1972 |
The central hypotensive action of amphetamine, ephedrine, phentermine, chlorphentermine and fenfluramine.
Topics: Amphetamine; Animals; Appetite Depressants; Blood Pressure; Cats; Chlorphentermine; Depression, Chemical; Ephedrine; Female; Fenfluramine; Haloperidol; Hypertension; Injections, Intravenous; Male; Phenethylamines; Phentermine; Reserpine; Sympatholytics; Vertebral Artery; Yohimbine | 1972 |
Effects of fenfluramine on the adrenergic system.
Topics: Amphetamine; Animals; Arteries; Blood Pressure; Electric Stimulation; Eyelids; Fenfluramine; Guanethidine; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Rats; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens | 1972 |
Role of monoamines in the anorexigenic actions of fenfluramine, amphetamine and p-chloromethamphetamine.
Topics: Amphetamine; Animals; Appetite Depressants; Biogenic Amines; Chlorine; Clomipramine; Cyproheptadine; Dextroamphetamine; Eating; Ergolines; Female; Fenfluramine; Haloperidol; Methamphetamine; Methyltyrosines; Methysergide; Rats; Rats, Inbred Strains | 1974 |
On the effect of anorectic drugs on striatum homovanillic acid in rats.
Topics: Amphetamine; Amphetamines; Animals; Appetite Depressants; Corpus Striatum; Dextroamphetamine; Diethylpropion; Dopamine; Female; Fenfluramine; Homovanillic Acid; Methamphetamine; Phenmetrazine; Phentermine; Phenylacetates; Rats | 1974 |
Drugs in obesity.
Topics: Amphetamine; Appetite Depressants; Diet, Reducing; Diuretics; Ephedrine; Fenfluramine; Health Education; Humans; Legislation, Drug; Metformin; Methylcellulose; Motivation; Obesity; Phenformin; Physical Exertion; South Africa; Thyroxine | 1974 |
Proceedings: Effect of the (minus)- and (plus)-isomers of fenfluramine and norfenfluramine on glucose uptake by the isolated rat hemidiaphragm.
Topics: Amphetamine; Animals; Diaphragm; Fenfluramine; Glucose; Glycogen; Hydrocarbons, Fluorinated; In Vitro Techniques; Insulin; Phenethylamines; Rats; Stereoisomerism; Structure-Activity Relationship | 1974 |
A mass fragmentographic study of amphetamine and metabolites in rat brain.
Topics: Amphetamine; Amphetamines; Animals; Brain; Brain Chemistry; Caudate Nucleus; Chromatography, Gas; Dextroamphetamine; Dopamine; Fenfluramine; Hypothalamus; In Vitro Techniques; Mass Spectrometry; Methamphetamine; Norfenfluramine; Phenylpropanolamine; Rats; Serotonin | 1974 |
The effect of p-chloroamphetamine on single Raphe neurons.
Topics: Action Potentials; Amphetamine; Animals; Body Temperature; Chlorine; Depression, Chemical; Fenfluramine; Male; Mesencephalon; Microelectrodes; Neurons; Potentiometry; Rats; Stereotaxic Techniques; Time Factors | 1974 |
Central action of anorexic agents: effects of amphetamine and fenfluramine in rats with lateral hypothalamic lesions.
Topics: Amphetamine; Analysis of Variance; Animals; Appetite Depressants; Body Weight; Feeding Behavior; Fenfluramine; Hypothalamus; Male; Rats; Stereotaxic Techniques; Time Factors | 1974 |
Studies on the relation of chemical structure to glycogenolytic activity in the brain.
Topics: Amines; Amphetamine; Animals; Benzene; Brain Chemistry; Dextroamphetamine; Diethylpropion; Dose-Response Relationship, Drug; Ephedrine; Fenfluramine; Glycogen; Male; Mescaline; Mice; Phenelzine; Phenethylamines; Phenylpropanolamine; Propane; Stereoisomerism; Structure-Activity Relationship; Time Factors; Tryptamines | 1972 |
The effects of selective lesioning of brain serotonin or catecholamine containing neurones on the anorectic activity of fenfluramine and amphetamine.
Topics: Amphetamine; Animals; Appetite Depressants; Brain Chemistry; Catecholamines; Cerebral Ventricles; Dextroamphetamine; Female; Fenfluramine; Hydroxydopamines; Mesencephalon; Neurons; Norepinephrine; Rats; Serotonin; Spectrometry, Fluorescence | 1972 |
[Rôle of anorectic agents and other drugs in treatment of obesity].
Topics: Amphetamine; Appetite Depressants; Diuretics; Drug Synergism; Fenfluramine; Humans; Obesity | 1972 |
The pattern of drug-taking among drug-dependent South African national servicemen.
Topics: Adolescent; Adult; Age Factors; Alcoholism; Amphetamine; Barbiturates; Cannabis; Cocaine; Datura stramonium; Drug Combinations; Ephedrine; Expectorants; Fenfluramine; Humans; Lysergic Acid Diethylamide; Male; Military Medicine; Opium; Phytotherapy; Plants, Medicinal; Plants, Toxic; South Africa; Substance-Related Disorders; Time Factors | 1972 |
No. 7 fenfluramine "Ponderax".
Topics: Administration, Oral; Amphetamine; Diarrhea; Diet, Reducing; Fenfluramine; Obesity | 1972 |
Proceedings: Central stimulant action of fenfluramine in the rat.
Topics: Amphetamine; Animals; Appetite Depressants; Behavior, Animal; Dextroamphetamine; Female; Fenfluramine; Male; Motor Activity; Rats; Stimulation, Chemical | 1972 |
Effect of some drugs on free fatty acids and triglycerides in plasma and tissues.
Topics: Amphetamine; Animals; Dietary Fats; Fatty Acids, Nonesterified; Fenfluramine; Glycogen; Heart; Heparin; Hydrocarbons, Fluorinated; Liver; Male; Myocardium; Nicotinic Acids; Oils; Perfusion; Phenethylamines; Rats; Time Factors; Triglycerides; Zea mays | 1972 |
D-amphetamine as a discriminative cue: drugs with similar stimulus properties.
Topics: Amphetamine; Animals; Avoidance Learning; Cues; Dextroamphetamine; Discrimination, Psychological; Female; Fenfluramine; Lysergic Acid Diethylamide; Mescaline; Nicotine; Rats | 1973 |
Fenfluramine blockade of CNS stimulant effects of amphetamines.
Topics: Amphetamine; Animals; Behavior, Animal; Dextroamphetamine; Drug Synergism; Fenfluramine; Male; Methamphetamine; Mice; Motor Activity; Phenobarbital; Rats; Sleep; Time Factors | 1973 |
[Similarities and differences between fenfluramine and amphetamine].
Topics: Amphetamine; Animals; Blood Pressure; Blood Vessels; Brain Chemistry; Drug Interactions; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Nerve Endings; Phenylacetates; Rats | 1973 |
Double-spot formation in the thin-layer chromatography of pure fenfluramine hydrochloride and some other amines in the presence of organic solvents.
Topics: Acetone; Amphetamine; Chloroform; Chromatography, Thin Layer; Ethanol; Ethylamines; Fenfluramine; Hydrolysis; Methanol; Methods; Solvents; Spectrophotometry, Ultraviolet | 1973 |
Dissociation of the anorexic effects of fenfluramine and amphetamine following intrahypothalamic injection.
Topics: Amphetamine; Animals; Appetite Depressants; Body Weight; Feeding Behavior; Fenfluramine; Hypothalamus; Injections; Male; Rats; Time Factors | 1973 |
Clinical toxicology. VII. Poisoning by salicylates, paracetamol, tricyclic antidepressants and a miscellany of drugs.
Topics: Acetaminophen; Adult; Amphetamine; Antidepressive Agents; Caustics; Digitalis; Fenfluramine; Humans; Male; Monoamine Oxidase Inhibitors; Phenacetin; Plants, Medicinal; Plants, Toxic; Poisoning; Salicylates | 1973 |
The effects of chronic fenfluramine administration on behaviour and body weight.
Topics: Amphetamine; Animals; Behavior, Animal; Body Weight; Drug Tolerance; Fenfluramine; Grooming; Humans; Male; Rats; Stereotyped Behavior; Time Factors | 1973 |
Antihypertensive effects of sympathomimetic amines.
Topics: Amines; Amphetamine; Animals; Blood Pressure; Depression, Chemical; Dogs; Ephedrine; Female; Fenfluramine; Heart Rate; Hypertension, Renal; Isoxsuprine; Male; Mecamylamine; Metaraminol; Methamphetamine; Methoxamine; Phenmetrazine; Phentermine; Phenylephrine; Sympathomimetics; Time Factors | 1973 |
Effects of various anorexigenic agents on open field behavior of rats.
Topics: Amphetamine; Animals; Appetite Depressants; Behavior, Animal; Benzphetamine; Fenfluramine; Male; Methamphetamine; Motor Activity; Phenmetrazine; Phentermine; Placebos; Rats; Time Factors | 1973 |
Medical treatment of obesity.
Topics: Amphetamine; Diet Therapy; Exercise Therapy; Fasting; Fenfluramine; Humans; Obesity | 1973 |
Effects of amphetamines on regional tryptophan hydroxylase activity and synaptosomal conversion of tryptophan to 5-hydroxytryptamine in rat brain.
Topics: Amphetamine; Animals; Brain; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Thin Layer; Dextroamphetamine; Fenfluramine; Histocytochemistry; In Vitro Techniques; Kinetics; Male; Mesencephalon; Methamphetamine; Microscopy, Fluorescence; Mixed Function Oxygenases; Nerve Endings; Rats; Serotonin; Subcellular Fractions; Sucrose; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1974 |
[Comparative action of fenfluramine and amphetamine in rats with hypothalamic obesity].
Topics: Amphetamine; Animal Nutritional Physiological Phenomena; Animals; Appetite Depressants; Body Weight; Brain; Drinking; Eating; Electrocoagulation; Fenfluramine; Fluorine; Hypothalamus; Obesity; Phenethylamines; Rats; Stereotaxic Techniques | 1969 |
Appetite suppression and central nervous system stimulation in the rhesus monkey.
Topics: Amphetamine; Animals; Appetite; Appetite Depressants; Azepines; Benzphetamine; Caffeine; Central Nervous System; Chlorphentermine; Diethylpropion; Feeding Behavior; Fenfluramine; Haplorhini; Indoles; Male; Methamphetamine; Motor Activity; Phenmetrazine; Sleep | 1971 |
A comparison of the effects of fenfluramine and amphetamine on uptake release and catabolism of norepinephrine in rat brain.
Topics: Amphetamine; Animals; Brain; Cerebral Cortex; Fenfluramine; In Vitro Techniques; Metabolism; Monoamine Oxidase Inhibitors; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Tritium | 1972 |
Methamphetamine, fenfluramine and their N-dealkylated metabolites: effect on monoamine concentrations in rat tissues.
Topics: Amphetamine; Animals; Brain; Brain Chemistry; Carbon Isotopes; Chromatography, Gas; Dopamine; Fenfluramine; Heart; Male; Mass Spectrometry; Methamphetamine; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1972 |
The role of monoamine oxidase in determining the amount of monoamines released by drugs in the central nervous system.
Topics: Amphetamine; Animals; Brain; Caudate Nucleus; Cerebral Cortex; Dopamine; Fenfluramine; In Vitro Techniques; Male; Medulla Oblongata; Models, Biological; Monoamine Oxidase; Norepinephrine; Pargyline; Rats; Serotonin; Stimulation, Chemical; Tritium | 1972 |
The possible central stimulant mechanisms of some appetite suppressants.
Topics: Amphetamine; Animals; Appetite Depressants; Catecholamines; Central Nervous System; Chlorphentermine; Diethylpropion; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Fenfluramine; Locomotion; Male; Methamphetamine; Methyltyrosines; Mice; Neurons; Pargyline; Phenethylamines; Phentermine; Rats; Reserpine; Stimulation, Chemical | 1972 |
Comparison of anorexigenic and behavioral potency of phenylethylamines.
Topics: Amphetamine; Animals; Appetite Depressants; Avoidance Learning; Behavior, Animal; Benzphetamine; Chlorine; Chlorphentermine; Diethylpropion; Feeding Behavior; Fenfluramine; Male; Methamphetamine; Morpholines; Phenethylamines; Phenmetrazine; Phentermine; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1972 |
Possible mechanism for the effect of anorexic agents on feeding and hoarding behaviour in rats.
Topics: Amphetamine; Animals; Appetite Depressants; Behavior, Animal; Chlorphentermine; Feeding Behavior; Fenfluramine; Homing Behavior; Hypothalamus; Injections, Intraperitoneal; Male; Rats | 1971 |
[Behavior of blood pressure during chronic effect of phenylalkylamines].
Topics: Amphetamine; Animals; Appetite Depressants; Blood Pressure; Chlorphentermine; Depression, Chemical; Female; Fenfluramine; Fluorine; Male; Phenethylamines; Phentermine; Rats; Stimulation, Chemical; Time Factors | 1969 |
A comparative study of the pharmacologic actions of amphetamine and fenfluramine.
Topics: Amphetamine; Animals; Appetite Depressants; Behavior, Animal; Blood Pressure; Dogs; Drug Synergism; Fenfluramine; Fluorine; Heart Rate; Male; Mice; Motor Activity; Phenethylamines; Rats; Reserpine | 1970 |
The treatment of obesity.
Topics: Adipose Tissue; Amphetamine; Appetite Depressants; Chorionic Gonadotropin; Diet Fads; Diet, Reducing; Digitalis Glycosides; Diuretics; Exercise Therapy; Fenfluramine; Hospitalization; Humans; Obesity; Psychotherapy; Starvation; Thyroid Hormones | 1971 |
Effects of fenfluramine on sleep-wakefulness in cats.
Topics: Amphetamine; Animals; Appetite Depressants; Cats; Electrodes; Fenfluramine; Fluorine; Phenethylamines; Sleep; Wakefulness | 1971 |
[On the analgesic effect of anorectic substances].
Topics: Amphetamine; Animals; Appetite Depressants; Codeine; Diethylpropion; Drug Synergism; Fenfluramine; Male; Mice; Pain; Phenmetrazine | 1967 |
A survey of the usage of amphetamines in parts of the Sidney community.
Topics: Amphetamine; Australia; Diethylpropion; Fenfluramine; Humans; Phenmetrazine; Sleep; Substance-Related Disorders | 1968 |
Determination of amphetamine and related amines in blood by gas chromatography.
Topics: Amines; Amphetamine; Chlorphentermine; Chromatography, Gas; Fenfluramine; Humans; Male; Methamphetamine | 1969 |
[Study on the excretion, localization and metabolism of a new anorexigenic substance: fenfluramine].
Topics: Adipose Tissue; Amphetamine; Animals; Appetite Depressants; Chromatography, Paper; Dogs; Fenfluramine; Humans | 1965 |
[Pharmacologic study of fenfluramine and its optical isomers].
Topics: Amphetamine; Animals; Appetite Depressants; Cardiovascular System; Central Nervous System; Dextroamphetamine; Dogs; Fenfluramine; Mice; Rabbits; Rats | 1966 |
The effect of viloxazine on drug-induced inhibition of food intake in the rat.
Topics: Amphetamine; Animals; Appetite Depressants; Dose-Response Relationship, Drug; Drug Interactions; Feeding Behavior; Fenfluramine; Male; Mazindol; Morpholines; Rats; Viloxazine | 1980 |
Behavioural analysis of feeding: implications for the pharmacological manipulation of food intake in animals and man.
Topics: Amphetamine; Animals; Antipsychotic Agents; Appetite Depressants; Body Weight; Eating; Feeding Behavior; Fenfluramine; Food Deprivation; Humans; Phenothiazines; Psychotic Disorders; Rats; Research Design; Species Specificity | 1980 |
Habituation of the head-poke response: effects of an amphetamine-barbiturate mixture, PLG and fenfluramine.
Topics: Amobarbital; Amphetamine; Animals; Exploratory Behavior; Fenfluramine; Male; Motor Activity; MSH Release-Inhibiting Hormone; Rats | 1981 |
Discriminative stimulus properties of fenfluramine: evidence for serotonergic involvement.
Topics: Amphetamine; Analysis of Variance; Animals; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Generalization, Stimulus; Male; Rats; Receptors, Serotonin; Satiation; Stereoisomerism | 1984 |
Improved gas-liquid chromatographic method for measuring fenfluramine and norfenfluramine in heparinised plasma.
Topics: Amphetamine; Chromatography, Gas; Fenfluramine; Heparin; Humans; Methamphetamine; Norfenfluramine | 1983 |
The effects of stereoisomers of 2-amino-6(7)- and 9-amino-6-trifluoromethylbenzonorbornenes on food intake, brain serotonin concentration, and monoamine oxidase activity.
Topics: Amphetamine; Animals; Brain; Brain Chemistry; Feeding Behavior; Fenfluramine; Male; Molecular Conformation; Monoamine Oxidase Inhibitors; Norbornanes; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Structure-Activity Relationship | 1984 |
Morphine-induced anorexia in lateral hypothalamic rats.
Topics: Amphetamine; Animals; Anorexia; Dextroamphetamine; Feeding and Eating Disorders; Fenfluramine; Humans; Hypothalamic Diseases; Hypothalamus; Male; Morphine; Rats; Serotonin | 1981 |
The selectivity of the anorectic effect of satietin. IV. The ineffectiveness of satietin on the sexual performance of male CFY rats.
Topics: Amphetamine; Animals; Appetite Depressants; Copulation; Fenfluramine; Fluoxetine; Glycopeptides; Male; Rats; Time Factors | 1982 |
The effects of stereoisomers of 2- and 9- aminobenzonorbornenes on food intake, brain serotonin concentration and monoamine oxidase activity in the rat.
Topics: Amphetamine; Animals; Brain; Feeding Behavior; Fenfluramine; Male; Molecular Conformation; Monoamine Oxidase; Norbornanes; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism | 1982 |
Differential effects of amphetamine and fenfluramine on dietary self-selection in rats.
Topics: Amphetamine; Animals; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Dose-Response Relationship, Drug; Energy Intake; Female; Fenfluramine; Food Preferences; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Comparison of the release of [3H]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine.
Topics: Amphetamine; Animals; Benztropine; Corpus Striatum; Dopamine; Fenfluramine; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Tritium | 1982 |
Effect of chronic administration of DL-amphetamine and fenfluramine on adrenocortical functions and on certain aspects of carbohydrate and fat metabolism.
Topics: Adrenal Cortex; Amphetamine; Animals; Blood Glucose; Carbohydrate Metabolism; Fatty Acids, Nonesterified; Fenfluramine; Lipid Metabolism; Liver; Liver Glycogen; Male; Phosphorylases; Rats | 1982 |
The selectivity of the anorectic effect of satietin. III. The ineffectiveness of satietin on metabolic rate, body temperature and blood pressure.
Topics: Amphetamine; Animals; Appetite Depressants; Blood Pressure; Body Temperature; Calcitonin; Ear; Female; Fenfluramine; Glycopeptides; Male; Metabolism; Oxygen Consumption; Rats; Rats, Inbred Strains; Regional Blood Flow | 1982 |
Chemical and pharmacological studies of anorectic drugs with phenylpiperazinyl structure.
Topics: Amphetamine; Animals; Appetite Depressants; Body Weight; Chemical Phenomena; Chemistry; Drinking; Eating; Fenfluramine; Lethal Dose 50; Male; Piperazines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Time Factors | 1982 |
Substituted phenethylamines and anorexia.
Topics: Amphetamine; Animals; Appetite Depressants; Biogenic Amines; Brain; Dopamine; Fenfluramine; Mazindol; Norepinephrine; Phenethylamines; Quipazine; Rats; Serotonin; Synaptosomes | 1980 |
Tolerance to anorectic drugs: pharmacological or artifactual.
Topics: Amphetamine; Animals; Appetite Depressants; Body Weight; Drug Tolerance; Eating; Female; Fenfluramine; Rats; Time Factors | 1981 |
Ontogeny of fenfluramine and amphetamine anorexia compared in rat pups.
Topics: Aging; Amphetamine; Animals; Body Weight; Dose-Response Relationship, Drug; Eating; Fenfluramine; Muridae | 1981 |
Characterisation of adjustments to the structure of feeding behaviour following pharmacological treatment: effects of amphetamine and fenfluramine and the antagonism produced by pimozide and methergoline.
Topics: Amphetamine; Animals; Ergolines; Feeding Behavior; Fenfluramine; Male; Metergoline; Mice; Pimozide; Rats | 1980 |
Dopamine agonists prevent or counteract the suppression of brain stimulation reward by fenfluramine.
Topics: Amphetamine; Animals; Brain; Dopamine Agonists; Electrodes, Implanted; Fenfluramine; Male; Medial Forebrain Bundle; Piribedil; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation | 1995 |
Effects of indorenate on food intake: a comparison with fenfluramine and amphetamine.
Topics: 5-Methoxytryptamine; Amphetamine; Animals; Dopamine Antagonists; Dose-Response Relationship, Drug; Drinking; Eating; Fenfluramine; Male; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Novel synergistic treatment of ethanol withdrawal seizures in rats with dopamine and serotonin agonists.
Topics: Alcohol Withdrawal Delirium; Amantadine; Amphetamine; Animals; Chlordiazepoxide; Dopamine Agonists; Drug Synergism; Drug Therapy, Combination; Fenfluramine; Male; Pyrimidines; Rats; Serotonin Receptor Agonists | 1995 |
Pharmacological evaluation of 2-amino-6(7)- and 9-amino-6-trifluoromethylbenzonorbornenes, the conformationally rigid analogues of norfenfluramine in mice.
Topics: Amphetamine; Analgesics; Animals; Drug Synergism; Female; Fenfluramine; Mice; Mice, Inbred ICR; Molecular Conformation; Morphine; Motor Activity; Norbornanes; Norfenfluramine; Pain Measurement | 1993 |
Anorectic specificity as measured in a choice paradigm in rhesus monkeys.
Topics: Amphetamine; Animals; Appetite Depressants; Choice Behavior; Cholecystokinin; Conditioning, Operant; Eating; Female; Fenfluramine; Food; Macaca mulatta; Male; Self Administration | 1993 |
Release of serotonin induced by 3,4-methylenedioxymethamphetamine (MDMA) and other substituted amphetamines in cultured fetal raphe neurons: further evidence for calcium-independent mechanisms of release.
Topics: Amphetamine; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Fenfluramine; N-Methyl-3,4-methylenedioxyamphetamine; Potassium Chloride; Raphe Nuclei; Rats; Serotonin | 1995 |
Injection of 5-HT into the nucleus accumbens reduces the effects of d-amphetamine on responding for conditioned reward.
Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Fenfluramine; Male; Metergoline; Nucleus Accumbens; Random Allocation; Rats; Rats, Sprague-Dawley; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists | 1996 |
Individual differences in reactivity to the rewarding/aversive properties of drugs: assessment by taste and place conditioning.
Topics: Amphetamine; Animals; Conditioning, Psychological; Fenfluramine; Lithium; Male; Morphine; Rats; Rats, Sprague-Dawley; Reward; Task Performance and Analysis | 1996 |
Dexfenfluramine lacks amphetamine-like abuse potential.
Topics: Amphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Fenfluramine; Macaca mulatta; Male; Rats; Rats, Inbred F344; Self Administration; Substance-Related Disorders | 1996 |
Behavioural and neurochemical characteristics of phentermine and fenfluramine administered separately and as a mixture in rats.
Topics: Amphetamine; Animals; Cocaine; Discrimination Learning; Dopamine; Dopamine Uptake Inhibitors; Drug Interactions; Fenfluramine; Illicit Drugs; Male; Microdialysis; Nicotine; Nucleus Accumbens; Phentermine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 1997 |
Carrier-dependent and Ca(2+)-dependent 5-HT and dopamine release induced by (+)-amphetamine, 3,4-methylendioxymethamphetamine, p-chloroamphetamine and (+)-fenfluramine.
Topics: Amphetamine; Animals; Calcium; Carrier Proteins; Dopamine; Fenfluramine; Male; Methiothepin; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Uptake Inhibitors; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin | 1997 |
Persistent loss of thermoregulation in the rat induced by 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy") but not by fenfluramine.
Topics: Amphetamine; Animals; Body Temperature Regulation; Dopamine Agents; Female; Fenfluramine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Serotonin Agents | 1998 |
Discriminative stimulus effects of S(-)-methcathinone (CAT): a potent stimulant drug of abuse.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Discrimination Learning; Fenfluramine; Haloperidol; Male; Propiophenones; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1998 |
Differential effects of monoaminergic agonists on alcohol intake in rats fed a tryptophan-enhanced diet.
Topics: Alcohol Drinking; Amphetamine; Animals; Appetite Depressants; Cerebral Cortex; Corpus Striatum; Dopamine; Fenfluramine; Food, Formulated; Hypothalamus; Phentermine; Rats; Rats, Long-Evans; Serotonin; Substance Withdrawal Syndrome; Tryptophan | 1999 |
The promotion effect of anorectic drugs on aflatoxin B(1)-induced hepatic preneoplastic foci.
Topics: Adipose Tissue, Brown; Aflatoxin B1; Amphetamine; Animals; Appetite Depressants; Biomarkers; Body Temperature Regulation; Carcinogens; Chemical and Drug Induced Liver Injury; Cocarcinogenesis; Dopamine; Drug Synergism; Eating; Energy Metabolism; Fenfluramine; Fluoxetine; gamma-Glutamyltransferase; Growth Disorders; Hypothyroidism; Liver Diseases; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Serotonin; Weight Loss | 1999 |
Simple and simultaneous analysis of fenfluramine, amphetamine and methamphetamine in whole blood by gas chromatography-mass spectrometry after headspace-solid phase microextraction and derivatization.
Topics: Adult; Amphetamine; Appetite Depressants; Calibration; Central Nervous System Stimulants; Chemical Phenomena; Chemistry, Physical; Drug Overdose; Female; Fenfluramine; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; Microchemistry; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Suicide; Time Factors | 2000 |
Effects of phentermine and fenfluramine on extracellular dopamine and serotonin in rat nucleus accumbens: therapeutic implications.
Topics: Amphetamine; Animals; Chlorphentermine; Cocaine; Dopamine; Extracellular Space; Fenfluramine; In Vitro Techniques; Iodine Radioisotopes; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Phentermine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sympathomimetics | 2000 |
Effects of fenfluramine and antidepressants on protein kinase C activity in rat cortical synaptoneurosomes.
Topics: Amphetamine; Animals; Antidepressive Agents; Cerebral Cortex; Dopamine Agents; Fenfluramine; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Synaptosomes | 2003 |
Comparison of (+)-methamphetamine, ±-methylenedioxymethamphetamine, (+)-amphetamine and ±-fenfluramine in rats on egocentric learning in the Cincinnati water maze.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Body Temperature; Body Weight; Central Nervous System Stimulants; Cold Temperature; Fenfluramine; Male; Maze Learning; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin Agents; Spatial Behavior; Swimming; Time Factors | 2011 |
Pimavanserin, a 5-HT2A inverse agonist, reverses psychosis-like behaviors in a rodent model of Parkinson's disease.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Disease Models, Animal; Dyskinesias; Fenfluramine; Fluorobenzenes; Hyperkinesis; Male; Motor Activity; Oxidopamine; Parkinson Disease; Piperidines; Psychotic Disorders; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Sensory Gating; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents; Serotonin Receptor Agonists; Substantia Nigra; Tyrosine 3-Monooxygenase; Urea | 2011 |
Rate-dependent effects of monoamine releasers on intracranial self-stimulation in rats: implications for abuse liability assessment.
Topics: Amphetamine; Animals; Biogenic Monoamines; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Fenfluramine; Male; Medial Forebrain Bundle; Methamphetamine; Norethandrolone; Rats; Rats, Sprague-Dawley; Regression Analysis; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors; Self Stimulation; Serotonin; Time Factors | 2013 |
Biphasic mechanisms of amphetamine action at the dopamine terminal.
Topics: Amphetamine; Animals; Biophysical Phenomena; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fenfluramine; Gene Expression Regulation; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nucleus Accumbens; Rats; Serotonin Agents; Time Factors | 2014 |
Serotonergic versus nonserotonergic dorsal raphe projection neurons: differential participation in reward circuitry.
Topics: Amphetamine; Animals; Dopamine; Dopaminergic Neurons; Dorsal Raphe Nucleus; Female; Fenfluramine; GABAergic Neurons; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Serotonergic Neurons; Serotonin; Ventral Tegmental Area | 2014 |
Abuse-Related Neurochemical Effects of Para-Substituted Methcathinone Analogs in Rats: Microdialysis Studies of Nucleus Accumbens Dopamine and Serotonin.
Topics: Amphetamine; Animals; Behavior, Animal; Designer Drugs; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fenfluramine; Male; Methamphetamine; Microdialysis; Nucleus Accumbens; Propiophenones; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Substance-Related Disorders; Synaptosomes | 2016 |
Decoding the Structure of Abuse Potential for New Psychoactive Substances: Structure-Activity Relationships for Abuse-Related Effects of 4-Substituted Methcathinone Analogs.
Topics: Amphetamine; Animals; Behavior, Animal; Dopamine Plasma Membrane Transport Proteins; Fenfluramine; Humans; Methamphetamine; Methylamines; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine Plasma Membrane Transport Proteins; Propiophenones; Psychotropic Drugs; Quantitative Structure-Activity Relationship; Rats; Self Administration; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Substance-Related Disorders | 2017 |