amphetamine has been researched along with dizocilpine maleate in 184 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (1.63) | 18.7374 |
| 1990's | 59 (32.07) | 18.2507 |
| 2000's | 65 (35.33) | 29.6817 |
| 2010's | 49 (26.63) | 24.3611 |
| 2020's | 8 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Fuller, RW; Hemrick-Luecke, S; Henderson, MG | 1 |
| Gessa, GL; Hmaidan, Y; Rossetti, ZL | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Ornstein, PL | 1 |
| Gong, XJ; Liu, GQ; Ping, HX; Wu, HQ; Xie, L | 1 |
| Layer, RT; Uretsky, NJ; Wallace, LJ | 1 |
| Snyder-Keller, AM | 2 |
| Fuller, RW; Hemrick-Luecke, SK; Henderson, MG | 1 |
| Damsma, G; Fibiger, HC; Robertson, GS; Tham, CS | 1 |
| Khansa, MR; Wolf, ME | 1 |
| Ford, LM; Giordano, M; Sanberg, PR; Shipley, MT | 1 |
| Calder, LD; Chaudhry, IA; Karler, R; Turkanis, SA | 2 |
| Cannon-Spoor, HE; Freed, WJ | 1 |
| Dimpfel, W; Spüler, M | 1 |
| Albertson, TE; Derlet, RW; Rice, P | 1 |
| Feldon, J; Lerner, T; Myslobodsky, MS | 1 |
| Martin, GE; Papp, NL | 1 |
| Brooks, K; Camacho, F; Corbett, R; Dunn, RW; Fishkin, RJ; Kerman, LL; Woods, AT | 1 |
| Bowyer, JF | 1 |
| Christensen, JR; Flory, GS; Miller, DW; Rebec, GV; White, IM | 1 |
| Florin, SM; Kuczenski, R; Segal, DS | 1 |
| Bedingfield, JB; Calder, LD; Karler, R; Thai, LH | 1 |
| Bankson, MG; Gibbs, S; Higley, D; Horger, BA; House, DT; McNamara, C; Schenk, S; Valadez, A | 1 |
| Dahlin, SL; White, FJ; Wolf, ME; Xue, CJ | 1 |
| Nencini, P; Valeri, P | 1 |
| Bresink, I; Danysz, W; Essmann, U; Wilke, R | 1 |
| Krug, D; Kunko, PM; Mueller, K; Saponjic, RM | 1 |
| Hu, XT; White, FJ; Wolf, ME | 1 |
| Amalric, M; Nieoullon, A; Ouagazzal, A | 1 |
| Jeziorski, M; Wolf, ME | 1 |
| Rückert, NG; Schmidt, WJ | 1 |
| Abercrombie, ED; Miller, DW | 1 |
| Hyman, SE; Konradi, C; Leveque, JC | 1 |
| Olds, ME | 1 |
| Berger, SP; Ho, LB; Reid, MS; Tolliver, BK | 1 |
| Ebert, U; Hedrich, HJ; Löscher, W; Nikkhah, G; Richter, A; Rosenthal, C | 1 |
| Gnegy, ME; Hewlett, GH; Pimputkar, G | 1 |
| Hölter, SM; Schmidt, WJ; Tzschentke, TM | 1 |
| Kronthaler, UO; Schmidt, WJ | 2 |
| De Vera, N; Ferré, S; Giménez-Llort, L; Martínez, E | 1 |
| Duke, MA; McDougall, SA; O'Neal, J | 1 |
| Schmidt, WJ; Tzschentke, TM | 2 |
| Fontana, D; Mele, A; Pert, A | 1 |
| Vanover, KE | 1 |
| De Vries, TJ; Schoffelmeer, AN; Vanderschuren, LJ | 1 |
| Mele, A; Pert, A; Thomas, DN | 1 |
| Cabeza de Vaca, S; Carr, KD | 1 |
| al-Amin, HA; Lipska, BK; Weinberger, DR | 1 |
| Davis, MD; Feifel, D; Reza, TL; Wustrow, DJ | 1 |
| Feifel, D; Reza, T | 1 |
| Bruce, KH; English, JA; Paul, IA | 1 |
| Li, Y; Wolf, ME | 1 |
| Carlsson, A; Carlsson, ML; Martin, P; Nilsson, M; Sorensen, SM; Waters, N; Waters, S | 1 |
| Heron-Maxwell, CL; O'Neill, MF; Shaw, G | 1 |
| O'Neill, MF; Shaw, G | 1 |
| Wolf, ME; Xue, CJ | 1 |
| Cioli, I; Duprè, S; Nencini, P; Pascucci, T; Pisetzky, F; Spirito, A | 1 |
| Duncan, GE; Leipzig, JN; Lieberman, JA; Miyamoto, S | 2 |
| Bourin, M; Kõks, S; Männistö, PT; Soosaar, A; Vasar, E; Võikar, V; Volke, V | 1 |
| Barber, DJ; Cooper, AJ; Griffiths, MR; Mitchell, IJ | 1 |
| Munn, E; Neklesa, T; Ranaldi, R; Wise, RA | 1 |
| Battisti, JJ; Uretsky, NJ; Wallace, LJ | 1 |
| Olufsen, K; Stolerman, IP | 1 |
| Berger, ML | 1 |
| Battisti, JJ; Shreffler, CB; Uretsky, NJ; Wallace, LJ | 1 |
| Chen, JC; Chiang, YC; Huang, YK; Liang, CS; Liang, KW | 1 |
| Feifel, D; Priebe, K; Shilling, PD | 1 |
| Carey, GJ; Cohen-Williams, M; Varty, GB; Walters, N | 1 |
| Blandini, F; Fancellu, R; Greenamyre, JT; Nappi, G | 1 |
| Fendt, M; Koch, M; Pedersen, V; Schulz, B | 1 |
| Bartoletti, M; Dall'Olio, R; Gaiardi, M; Gandolfi, O; Gubellini, C | 1 |
| Baunez, C; Bernardi, G; Borrelli, E; Calabresi, P; Centonze, D; Picconi, B; Pisani, A | 1 |
| Halim, ND; Lipska, BK; Segal, PN; Weinberger, DR | 1 |
| Assis, A; Cancela, LM; Gioino, G; Pacchioni, AM | 1 |
| De Leonibus, E; Mele, A; Oliverio, A; Pert, A | 1 |
| Geyer, MA; Lehmann-Masten, V; Low, MJ; Otero-Corchon, V; Ralph-Williams, RJ | 1 |
| Feifel, D; Shilling, PD | 1 |
| Brentani, RR; Coitinho, AS; Dall'Igna, OP; Dietrich, MO; Hoffmann, A; Izquierdo, I; Lara, DR; Martins, VR; Souza, DO | 1 |
| Atack, JR; Bromidge, FA; Dawson, GR; Newman, RJ; O'Meara, GF; Reynolds, DS; Rosahl, TW; Whiting, PJ | 1 |
| van den Buuse, M | 2 |
| Caron, MG; Gainetdinov, RR; Gerber, DJ; Leiter, LM; Miyakawa, T; Sotnikova, TD; Tonegawa, S; Zeng, H | 1 |
| Janać, B; Rakić, Lj; Stojiljković, M; Vasilev, V; Veskov, R | 1 |
| Dall'Igna, OP; Dietrich, MO; Hoffmann, A; Lara, DR; Lourenço Da Silva, A; Souza, DO | 1 |
| Lawrence, AJ; Ledent, C; Short, J; van den Buuse, M; Wang, JH | 1 |
| Janać, B; Milanović, D; Pesić, V; Rakić, L; Tomić, M; Veskov, R | 1 |
| Kretschmer, BD; Steiniger, B | 1 |
| Cardon, M; Cohen, H; Kipnis, J; Schwartz, M; Ziv, Y | 1 |
| Dall'Igna, OP; Dietrich, MO; dos Anjos, GM; Lara, DR; Mantese, CE; Souza, DO; Tort, AB | 1 |
| Lawrence, AJ; Martin, S; van den Buuse, M | 1 |
| Dietrich, MO; Dos Anjos, GM; Lara, DR; Mantese, CE; Perry, ML; Rotta, LN; Souza, DO | 1 |
| Covington, HE; Datta, R; Gale, MC; Miczek, KA; Yap, JJ | 1 |
| Bashkatova, V; Hornick, A; Kraus, MM; Prast, H; Vanin, A | 1 |
| Bowyer, JF; Delongchamp, RR; Jakab, RL | 1 |
| Martin, S; Pijnappel, M; Samuelson, LC; van den Buuse, M; van Driel, IR | 1 |
| Dall'Igna, OP; de Oliveira, RV; Lara, DR; Neto, PF; Santos Gomes, MW; Schuh, JF; Souza, DO; Tort, AB | 1 |
| Le Grevès, P | 1 |
| Demyanenko, GP; Gilmore, KL; Huang, JZ; Maness, PF; Panicker, AK; Pillai-Nair, N; Rodriguiz, RM; Wetsel, WC | 1 |
| Dall'Igna, OP; Lara, DR; Souza, DO; Tort, AB | 1 |
| Brosda, J; Hendry, I; Leck, KJ; Martin, S; Matthaei, KI; van den Buuse, M | 1 |
| Derks, N; Ellenbroek, BA; Park, HJ | 1 |
| Abraini, JH; Ansseau, M; David, HN; Lemaire, M | 1 |
| Both, FL; Elisabetsky, E; Henriques, AT; Kerber, VA; Meneghini, L | 1 |
| Bregonzio, C; Cador, M; Cancela, LM; Pacchioni, AM | 1 |
| Amaral, OB; Kazlauckas, V; Lara, DR; Neto, WP; Souza, DO; Tort, AB | 1 |
| Chapin, DS; Fujiwara, RA; James, LC; McCarthy, SA; McNeish, JD; Menniti, FS; Schmidt, CJ; Siuciak, JA; Stock, JL; Strick, CA; Williams, RD | 1 |
| da Silva, AL; Dall'Igna, OP; Hoffmann, A; Lara, DR; Souza, DO | 1 |
| Anderson, GT; Barido, R; Bonhaus, DW; Brann, MR; Brunmark, P; Davis, RE; Dyssegaard, A; Gardell, LR; Hacksell, U; Johnson, RW; Pounds, L; Tabatabaei, A; Vanover, KE; Veinbergs, I | 1 |
| Andrieux, A; Bégou, M; Bertrand, JB; Brun, P; D'Amato, T; Job, D; Saoud, M; Schweitzer, A; Suaud-Chagny, MF | 1 |
| Herzig, V; Sadler, R; Schmidt, WJ | 1 |
| Boison, D; Chen, JF; Feldon, J; Singer, P; Yee, BK | 1 |
| Guimarães, FS; Leite, JV; Moreira, FA | 1 |
| Davisson, RL; Lawrence, AJ; Markus, MA; Martin, S; Morris, BJ; van den Buuse, M | 1 |
| Chapin, DS; Harms, JF; Martin, AN; McCarthy, SA; Schmidt, CJ; Siuciak, JA | 1 |
| Davis, RE; Vanover, KE; Veinbergs, I | 1 |
| Frauli, M; Hess, G; Kłodzińska, A; Neuville, P; Pałucha-Poniewiera, A; Pilc, A; Schann, S; Stachowicz, K; Tokarski, K | 1 |
| Brown, AS; Butler, PD; Keegan, D; Palmer, AA; Rotrosen, J; Siska, LD; Susser, E | 1 |
| Arad, M; Barak, S; Black, MD; Boulay, D; De Levie, A; Griebel, G; Pichat, P; Varty, GB; Weiner, I | 1 |
| Beninger, RJ; Boegman, RJ; Forsyth, JK; Jhamandas, K; Reynolds, JN; Van Adel, M | 1 |
| Catuogno, V; Centonze, D; D'Aniello, A; Errico, F; Fisone, G; Napolitano, F; Rossi, S; Topo, E; Usiello, A | 1 |
| Davis, RJ; Degroot, A; Nomikos, GG; Tzavara, ET; Wade, MR | 1 |
| Assis, MA; Cancela, LM; Hansen, C; Lux-Lantos, V | 1 |
| Button, D; Feifel, D; Melendez, G; Pang, Z; Schreiber, R; Shilling, PD | 1 |
| Hinchliffe, RM; Huszar, SL; Hutson, PH; Pachmerhiwala, R; Smith, SM; Uslaner, JM; Vardigan, JD | 1 |
| Avenet, P; Bergis, O; Boulay, D; Griebel, G | 1 |
| Ardayfio, PA; Carlezon, WA; Choi, YK; Hwang, DY; Kim, KS; Leung, A; Moran-Gates, T; Park, J; Tarazi, FI | 1 |
| Abazyan, B; Ayhan, Y; Cadet, JL; Kim, R; Krasnova, IN; Ladenheim, B; Margolis, RL; Mori, S; Nomura, J; Pletnikov, MV; Ross, CA; Sawa, A; Vogel, MW | 1 |
| Brocia, C; Fienberg, AA; Flajolet, M; Greengard, P; Nairn, AC; Rebholz, H; Warner-Schmidt, JL; Zhou, M | 1 |
| Ashby, DM; Beninger, RJ; Dringenberg, HC; Habib, D; Reynolds, JN | 1 |
| Berk, M; Bush, AI; Copolov, DL; Dean, O; van den Buuse, M | 1 |
| Gnegy, ME; Jutkiewicz, EM; Kim, MN; Zhang, M | 1 |
| Barrow, JC; Clark, J; Hinchliffe, RM; Huszar, SL; Hutson, PH; Nguyen, SJ; Pachmerhiwala, R; Renger, JJ; Smith, SM; Surles, NO; Uebele, VN; Uslaner, JM; Vardigan, JD; Yao, L | 1 |
| Barak, S; Weiner, I | 1 |
| Ahlbrand, R; Bronson, SL; Horn, PS; Kern, JR; Richtand, NM | 1 |
| Fletcher, PJ; Higgins, GA; Noble, K; Rizos, Z | 1 |
| Bai, X; France, CP; Gerak, LR | 1 |
| Callaerts-Vegh, Z; D'Hooge, R; Meert, T; Moechars, D; Naert, A | 1 |
| Larrauri, JA; Levin, ED | 2 |
| Akhtar, M; Khanam, R; Mahmood, D; Pillai, KK | 1 |
| Burne, TH; Cowin, G; Eyles, DW; Harms, LR; Kurniawan, ND; McGrath, JJ | 1 |
| Braun, AA; Graham, DL; Richtand, NM; Schaefer, TL; Skelton, MR; Vorhees, CV; Williams, MT | 1 |
| Abazyan, B; Abazyan, S; Ma, TM; Nomura, J; Pletnikov, MV; Sawa, A; Seshadri, S; Snyder, SH; Yang, C | 1 |
| Beninger, RJ; Hawken, ER; Lister, J; Winterborn, AN | 1 |
| Burne, TH; Eyles, DW; Groves, NJ; Kesby, JP; Mackay-Sim, A; McGrath, JJ | 1 |
| Damazo, AS; Ferraz de Paula, V; Hamasato, EK; Ligeiro de Oliveira, AP; Lino-dos-Santos-Franco, A; Palermo-Neto, J; Peron, JP; Ribeiro, A; Tavares-de-Lima, W | 1 |
| Doller, D; Gruca, P; Kusek, M; Lasoń-Tyburkiewicz, M; Marciniak, M; Papp, M; Pilc, A; Stachowicz, K; Sławińska, A; Tokarski, K; Wierońska, JM | 1 |
| Huston, JP; Petri, D; Pum, M; Schnitzler, A; Vesper, J | 1 |
| Duncan, JR; Gibbs, SJ; Lawrence, AJ | 1 |
| Burne, TH; Byrne, JH; Eyles, DW; McGrath, JJ; Turner, KM; Voogt, M | 1 |
| Bosse, KE; Gnegy, ME; Jutkiewicz, EM; Kennedy, RT; Mabrouk, OS; Schultz-Kuszak, KN; Traynor, JR | 1 |
| Agster, KL; Baker, LK; Bodfish, JW; Moy, SS; Nadler, JJ; Nikolova, VD; Nonneman, RJ; Riddick, NV; Teng, BL; Young, NB | 1 |
| Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A | 1 |
| Gulley, JM; Hammerslag, LR; Waldman, AJ | 1 |
| Aerts, N; Steckler, T; Talpos, J; Waddell, J | 1 |
| Burke, DA; Hall, BJ; Larrauri, JA; Levin, ED | 1 |
| Adrien, J; Belmer, A; Maroteaux, L; Moutkine, I; Pitychoutis, PM | 1 |
| Costa, G; Morelli, M; Simola, N | 1 |
| Biawat, P; Cook, JM; Joksimović, S; Marković, B; Savić, MM; Stanković, T; Timić Stamenić, T | 1 |
| Beloate, LN; Casey, GR; Coolen, LM; Webb, IC; Weems, PW | 1 |
| Del-Bel, E; Michel, PP; Raisman-Vozari, R; Salum, C; Schmidt, F | 1 |
| Acher, F; Gruca, P; Lasoń-Tyburkiewicz, M; Marciniak, M; Papp, M; Pilc, A; Wierońska, JM; Woźniak, M | 1 |
| Engler, A; Engler, H; Feldon, J; Giovanoli, S; Meyer, U; Richetto, J; Riva, MA; Schedlowski, M | 1 |
| Gawel, K; Gibula-Bruzda, E; Jenda, M; Kotlinska, JH; Marszalek-Grabska, M | 1 |
| Alijanpour, S; Amini-Khoei, H; Amiri, S; Ghaderi, M; Ghazi-Khansari, M; Haj-Mirzaian, A; Rahimi-Balaei, M; Rastegar, M; Tirgar, F; Zarrindast, MR | 1 |
| Hauber, W; Roschlau, C; Votteler, A | 1 |
| Chang, ST; Huang, CL; Huang, NK; Tung, CS | 1 |
| Gallant, S; Martone, P; Shalev, U; Welch, L | 1 |
| Ahnaou, A; Drinkenburg, WHIM; Huysmans, H; Van de Casteele, T | 1 |
| Afshari, K; Amini-Khoei, H; Amiri, S; Dehpour, AR; Ghesmati, M; Haj-Mirzaian, A; Hashemiaghdam, A; Ramezanzadeh, K | 1 |
| Del-Bel, E; Dos-Santos-Pereira, M; Issy, AC; Kubrusly, RCC; Pedrazzi, JFC | 1 |
| Acher, F; Cieślik, P; Conn, PJ; Kusek, M; Pilc, A; Rook, JM; Tantawy, MN; Tokarski, K; Wierońska, JM; Woźniak, M | 1 |
| Callahan, PM; Menniti, FS; Nelson, FR; Terry, AV; Vinod, AB; Volkmann, RA; Zainuddin, M | 1 |
| Kosmowska, B; Ossowska, K; Wardas, J | 1 |
| Balenovic, I; Blagaic, AB; Cilic, M; Drmic, D; Filipcic, I; Ilic, S; Kokot, A; Seiwerth, S; Sikiric, P; Strbe, S; Tvrdeic, A; Vukojevic, J; Zemba Cilic, A; Zemba, M; Zoricic, Z | 1 |
| Göktalay, G; Oral, S | 1 |
| Crippa, JAS; Del Bel, E; Guimarães, FS; Joca, SRL; Pedrazzi, JFC; Sales, AJ | 1 |
| Benvenutti, R; Chitolina, R; Gallas-Lopes, M; Herrmann, AP; Marcon, M; Piato, A; Reis, CG; Sachett, A; Strogulski, NR | 1 |
| Głuch-Lutwin, M; Jaśkowska, J; Kołaczkowski, M; Lustyk, K; Mierzejewski, P; Mordyl, B; Pytka, K; Sapa, J; Zakrzewska-Sito, A; Żmudzka, E | 1 |
| Juza, R; Kelemen, E; Korabecny, J; Petrasek, T; Soukup, O; Stuchlik, A; Tuckova, K; Vojtechova, I | 1 |
184 other study(ies) available for amphetamine and dizocilpine maleate
| Article | Year |
|---|---|
MK-801 protects against amphetamine-induced striatal dopamine depletion in iprindole-treated rats, but not against brain serotonin depletion after p-chloroamphetamine administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain; Corpus Striatum; Dizocilpine Maleate; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Iprindole; Mice; p-Chloroamphetamine; Rats; Serotonin | 1992 |
Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Ethanol; Male; Morphine; Naloxone; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 1992 |
Protection against amphetamine-induced neurotoxicity toward striatal dopamine neurons in rodents by LY274614, an excitatory amino acid antagonist.
Topics: Amino Acids; Amphetamine; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Iprindole; Isoquinolines; Male; Methamphetamine; Mice; Nervous System Diseases; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1992 |
Effect of dizocilpine maleate on monoamines and their metabolites in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Corpus Striatum; Dizocilpine Maleate; Dopamine; Limbic System; Male; Rats; Rats, Inbred Strains | 1992 |
Effects of morphine in the nucleus accumbens on stimulant-induced locomotion.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Caffeine; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine Agents; Glutamine; Ibotenic Acid; Male; Morphine; Motor Activity; Neural Pathways; Nucleus Accumbens; Oligopeptides; Picrotoxin; Rats; Scopolamine; Synaptic Transmission | 1991 |
Striatal c-fos induction in neonatally dopamine-depleted rats given transplants.
Topics: Amphetamine; Animals; Animals, Newborn; Calbindins; Corpus Striatum; Dizocilpine Maleate; Dopamine; Immunohistochemistry; Immunologic Techniques; Nerve Tissue; Neurons; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; S100 Calcium Binding Protein G; Staining and Labeling | 1991 |
MK801 antagonism of the prolonged depletion of striatal dopamine by amphetamine in iprindole-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Dopamine; Homovanillic Acid; Iprindole; Male; Rats; Rats, Inbred Strains | 1992 |
Striatal c-fos induction by drugs and stress in neonatally dopamine-depleted rats given nigral transplants: importance of NMDA activation and relevance to sensitization phenomena.
Topics: Amphetamine; Animals; Animals, Newborn; Brain Tissue Transplantation; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Female; Immunohistochemistry; Male; N-Methylaspartate; Neurons; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Stereotyped Behavior; Stress, Physiological; Substantia Nigra; Transcription Factors | 1991 |
Dopaminergic regulation of striatal acetylcholine release: importance of D1 and N-methyl-D-aspartate receptors.
Topics: Acetylcholine; Amphetamine; Animals; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Extracellular Space; Indoles; Male; Nomifensine; Phenanthridines; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Salicylamides | 1991 |
Repeated administration of MK-801 produces sensitization to its own locomotor stimulant effects but blocks sensitization to amphetamine.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Drug Administration Schedule; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reference Values | 1991 |
Neural grafts and pharmacological intervention in a model of Huntington's disease.
Topics: Acetylcholinesterase; Amphetamine; Animals; Brain Tissue Transplantation; Catalepsy; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Electron Transport Complex IV; Female; Fetal Tissue Transplantation; Huntington Disease; Immunohistochemistry; Kainic Acid; Motor Activity; Nerve Degeneration; Pregnancy; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1990 |
Amphetamine behavioral sensitization and the excitatory amino acids.
Topics: Amino Acids; Amphetamine; Animals; Behavior, Animal; Cyproheptadine; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Ketamine; Male; Mice; Neuroeffector Junction; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1990 |
A possible role of AA2 excitatory amino acid receptors in the expression of stimulant drug effects.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Amphetamine; Animals; Apomorphine; Behavior, Animal; Central Nervous System Stimulants; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glutamates; Mice; Motor Activity; Phencyclidine; Quinoxalines; Receptors, Amino Acid; Receptors, Cell Surface; Stereotyped Behavior | 1990 |
Dizocilpine (MK-801), ketamine and phencyclidine: low doses affect brain field potentials in the freely moving rat in the same way as activation of dopaminergic transmission.
Topics: Amphetamine; Animals; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Ketamine; Levodopa; Male; Membrane Potentials; Mice; Phencyclidine; Rats; Rats, Inbred F344; Synaptic Transmission; Time Factors | 1990 |
Antagonism of cocaine, amphetamine, and methamphetamine toxicity.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Diazepam; Dimethyl Sulfoxide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes, Implanted; Haloperidol; Lethal Dose 50; Male; Methamphetamine; N-Methylaspartate; Propranolol; Rats; Rats, Inbred Strains; Seizures | 1990 |
Blockade of "reverse tolerance" to cocaine and amphetamine by MK-801.
Topics: Amphetamine; Animals; Anticonvulsants; Cocaine; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Haloperidol; Male; Mice; Motor Activity; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior | 1989 |
Amphetamine potentiation of anti-conflict action of chlordiazepoxide.
Topics: Amphetamine; Animals; Anticonvulsants; Chlordiazepoxide; Conflict, Psychological; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Male; Rats; Rats, Inbred Strains | 1986 |
Blockade of MK-801 induced ipsiversive turning in 6-OHDA lesioned rats by alpha 1-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Anticonvulsants; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Butyrophenones; Dibenzazepines; Dibenzocycloheptenes; Dizocilpine Maleate; Female; Humans; Hydroxydopamines; Oxidopamine; Postural Balance; Prazosin; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra | 1984 |
Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors.
Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Social Behavior | 1995 |
The role of hyperthermia in amphetamine's interactions with NMDA receptors, nitric oxide, and age to produce neurotoxicity.
Topics: Aging; Amphetamine; Animals; Arginine; Brain; Dizocilpine Maleate; Fever; Glutamic Acid; Haloperidol; Methamphetamine; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1995 |
Amphetamine, cocaine, and dizocilpine enhance performance on a lever-release, conditioned avoidance response task in rats.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1995 |
Does dizocilpine (MK-801) selectively block the enhanced responsiveness to repeated amphetamine administration?
Topics: Amphetamine; Animals; Arousal; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1995 |
A dopaminergic-glutamatergic basis for the action of amphetamine and cocaine.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Male; Mice; Piperazines; Quinoxalines; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Sulpiride | 1994 |
Development and expression of sensitization to cocaine's reinforcing properties: role of NMDA receptors.
Topics: Amphetamine; Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Self Administration | 1993 |
MK-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens.
Topics: Amphetamine; Animals; Cocaine; Dizocilpine Maleate; Dopamine; Extracellular Space; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
The role of opioid mechanisms in the anorectic effects of stimulants: U50,488H enhances amphetamine inhibition of free feeding in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amphetamine; Animals; Appetite Depressants; Central Nervous System Stimulants; Diuresis; Dizocilpine Maleate; Dopamine; Drinking; Drug Synergism; Eating; Endorphins; Haloperidol; Male; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Urodynamics | 1994 |
Glutamate antagonists have different effects on spontaneous locomotor activity in rats.
Topics: Amphetamine; Animals; Ataxia; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Motor Activity; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Synaptic Membranes | 1994 |
The effects of haloperidol, scopolamine, and MK-801 on amphetamine-induced increases in ascorbic and uric acid as determined by voltammetry in vivo.
Topics: Amphetamine; Animals; Ascorbic Acid; Caudate Nucleus; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes; Haloperidol; Male; Rats; Rats, Wistar; Scopolamine; Uric Acid | 1994 |
MK-801 prevents alterations in the mesoaccumbens dopamine system associated with behavioral sensitization to amphetamine.
Topics: Amphetamine; Animals; Behavior, Animal; Dizocilpine Maleate; Dopamine; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Tegmentum Mesencephali | 1994 |
Locomotor activation induced by MK-801 in the rat: postsynaptic interactions with dopamine receptors in the ventral striatum.
Topics: Amphetamine; Animals; Brain; Brain Diseases; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Drug Interactions; Haloperidol; Male; Microinjections; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Synapses | 1994 |
Coadministration of MK-801 with amphetamine, cocaine or morphine prevents rather than transiently masks the development of behavioral sensitization.
Topics: Amphetamine; Analysis of Variance; Animals; Cocaine; Dizocilpine Maleate; Drug Interactions; Male; Morphine; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 1993 |
The sigma receptor ligand 1,3-di-(2-tolyl)guanidine in animal models of schizophrenia.
Topics: Amphetamine; Animals; Behavior, Animal; Binding Sites; Dizocilpine Maleate; Guanidines; Male; Models, Biological; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, sigma; Schizophrenia | 1993 |
Effects of MK-801 on spontaneous and amphetamine-stimulated dopamine release in striatum measured with in vivo microdialysis in awake rats.
Topics: Amphetamine; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 1996 |
Amphetamine and dopamine-induced immediate early gene expression in striatal neurons depends on postsynaptic NMDA receptors and calcium.
Topics: Amphetamine; Animals; Base Sequence; Binding Sites; Calcium; Corpus Striatum; Dizocilpine Maleate; Dopamine; Gene Expression; Genes, Immediate-Early; Male; Molecular Sequence Data; Neurons; Oligonucleotide Probes; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Synapses | 1996 |
Dopaminergic basis for the facilitation of brain stimulation reward by the NMDA receptor antagonist, MK-801.
Topics: Amphetamine; Analysis of Variance; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Haloperidol; Hypothalamus; Male; Rats; Rats, Sprague-Dawley; Self Stimulation | 1996 |
Evidence for dissociable mechanisms of amphetamine- and stress-induced behavioral sensitization: effects of MK-801 and haloperidol pretreatment.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Dizocilpine Maleate; Haloperidol; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Physiological | 1996 |
Behavioral and neurochemical dysfunction in the circling (ci) rat: a novel genetic animal model of a movement disorder.
Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Agonists; Female; Forelimb; Male; Motor Activity; Motor Skills; Movement Disorders; Mutation; Rats; Rats, Inbred Lew; Stereotyped Behavior | 1996 |
Haloperidol and MK-801 block increases in striatal calmodulin resulting from repeated amphetamine treatment.
Topics: Amphetamine; Animals; Calmodulin; Calmodulin-Binding Proteins; Corpus Striatum; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Female; Haloperidol; Rats; Rats, Sprague-Dawley | 1996 |
Effects of amphetamine, morphine and dizocilpine (MK-801) on spontaneous alternation in the 8-arm radial maze.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1996 |
1S,3R-ACPD has cataleptogenic effects and reverses MK-801-, and less pronounced, D,L-amphetamine-induced locomotion.
Topics: Amphetamine; Animals; Catalepsy; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Locomotion; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reaction Time | 1996 |
Motor depressant effects of systemically administered polyamines in mice: involvement of central NMDA receptors.
Topics: Amphetamine; Animals; Biogenic Polyamines; Brain; Brain Chemistry; Dizocilpine Maleate; Male; Mice; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Theophylline | 1996 |
Ontogeny of dopamine agonist-induced sensitization: role of NMDA receptors.
Topics: Amphetamine; Animals; Animals, Suckling; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Female; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1997 |
Interactions of MK-801 and GYKI 52466 with morphine and amphetamine in place preference conditioning and behavioural sensitization.
Topics: Amphetamine; Animals; Anti-Anxiety Agents; Benzodiazepines; Central Nervous System Stimulants; Conditioning, Operant; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Alterations in striatal dopamine overflow during rotational behavior induced by amphetamine, phencyclidine, and MK-801.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; Neostriatum; Phencyclidine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra | 1997 |
Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Dioxoles; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Haloperidol; Locomotion; Male; Mice; Piperidines; Receptors, AMPA | 1997 |
Does dizocilpine (MK-801) inhibit the development of morphine-induced behavioural sensitization in rats?
Topics: Amphetamine; Animals; Behavior, Animal; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Wistar | 1997 |
Different neural mechanisms underlie dizocilpine maleate- and dopamine agonist-induced locomotor activity.
Topics: Amphetamine; Animals; Behavior, Animal; Dizocilpine Maleate; Dopamine Agonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; Globus Pallidus; Hydroxydopamines; Ibotenic Acid; Male; Microdialysis; Motor Activity; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1998 |
Food restriction enhances the central rewarding effect of abused drugs.
Topics: Amphetamine; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Energy Intake; Excitatory Amino Acid Antagonists; Food Deprivation; Locomotion; Male; Nicotine; Nicotinic Agonists; Phencyclidine; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Substance-Related Disorders; Sympathomimetics | 1998 |
The mGluRs group II agonist (2S,3S,4S)-alpha-carboxycyclopropyl-glycine induces catalepsy in the rat, which is pronouncedly antagonised by dizocilpine and D,L-amphetamine.
Topics: Amino Acids, Dicarboxylic; Amphetamine; Animals; Catalepsy; Cerebral Ventricles; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Infusions, Parenteral; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 1998 |
Excitotoxic lesions of the rat medial prefrontal cortex. Effects on abnormal behaviors associated with neonatal hippocampal damage.
Topics: Amphetamine; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Hippocampus; In Situ Hybridization; Motor Activity; Prefrontal Cortex; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stereotyped Behavior | 1998 |
Discrete quinolinic acid lesions of the rat prelimbic medial prefrontal cortex affect cocaine- and MK-801-, but not morphine- and amphetamine-induced reward and psychomotor activation as measured with the place preference conditioning paradigm.
Topics: Amphetamine; Analgesics, Opioid; Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Male; Morphine; Motor Activity; Prefrontal Cortex; Psychomotor Performance; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reward | 1998 |
Novel antipsychotic-like effects on prepulse inhibition of startle produced by a neurotensin agonist.
Topics: Adrenergic Agents; Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Hallucinogens; Male; Neurotensin; Rats; Rats, Sprague-Dawley; Reflex, Startle | 1999 |
Oxytocin modulates psychotomimetic-induced deficits in sensorimotor gating.
Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Hallucinogens; Male; N-Methylaspartate; Oxytocin; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia | 1999 |
Increased discriminative stimulus potency of phencyclidine in C57B1/6 mice infected with the LP-BM5 retrovirus.
Topics: Adrenergic Agents; Amphetamine; Animals; Discrimination Learning; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Leukemia Virus, Murine; Male; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Phencyclidine; Psychomotor Performance; Sensitivity and Specificity; Time Factors | 1999 |
Can the "state-dependency" hypothesis explain prevention of amphetamine sensitization in rats by NMDA receptor antagonists?
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Hypersensitivity; Excitatory Amino Acid Antagonists; Male; Motor Activity; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Chloride | 1999 |
The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Haloperidol; Hyperkinesis; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Piperazines; Piperidines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists | 1999 |
5-HT2 receptor antagonism reduces hyperactivity induced by amphetamine, cocaine, and MK-801 but not D1 agonist C-APB.
Topics: Aminopyridines; Amphetamine; Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Agonists; Drug Interactions; Female; Fluorobenzenes; Indoles; Mice; Motor Activity; Piperidines; Ritanserin; Serotonin Antagonists | 1999 |
Comparison of dopamine receptor antagonists on hyperlocomotion induced by cocaine, amphetamine, MK-801 and the dopamine D1 agonist C-APB in mice.
Topics: Amphetamine; Analysis of Variance; Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Locomotion; Mice; Receptors, Dopamine D1 | 1999 |
Amphetamine-induced glutamate efflux in the rat ventral tegmental area is prevented by MK-801, SCH 23390, and ibotenic acid lesions of the prefrontal cortex.
Topics: Amphetamine; Animals; Benzazepines; Dizocilpine Maleate; Ibotenic Acid; Kinetics; Male; Microdialysis; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 1999 |
Acamprosate does not antagonise the discriminative stimulus properties of amphetamine and morphine in rats.
Topics: Acamprosate; Alcohol Deterrents; Amphetamine; Animals; Central Nervous System Stimulants; Discrimination Learning; Dizocilpine Maleate; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reaction Time; Taurine | 1999 |
Comparison of brain metabolic activity patterns induced by ketamine, MK-801 and amphetamine in rats: support for NMDA receptor involvement in responses to subanesthetic dose of ketamine.
Topics: Amphetamine; Animals; Autoradiography; Biological Transport; Brain; Carbon Radioisotopes; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reference Values; Tissue Distribution | 1999 |
Apomorphine-induced behavioural sensitization in rats: individual differences, role of dopamine and NMDA receptors.
Topics: Amphetamine; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1999 |
Pharmacological mechanisms mediating phencyclidine-induced apoptosis of striatopallidal neurons: the roles of glutamate, dopamine, acetylcholine and corticosteroids.
Topics: Acetylcholine; Adrenal Cortex Hormones; Amphetamine; Animals; Apoptosis; Behavior, Animal; Benzazepines; Biogenic Monoamines; Central Nervous System Stimulants; Cerebral Cortex; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Globus Pallidus; Glutamic Acid; Hormone Antagonists; Male; Mifepristone; Muscarinic Antagonists; Neostriatum; Neurons; Phencyclidine; Quinpirole; Rats; Rats, Sprague-Dawley; Scopolamine; Stress, Physiological | 2000 |
Effects of ketamine, MK-801, and amphetamine on regional brain 2-deoxyglucose uptake in freely moving mice.
Topics: Amphetamine; Animals; Autoradiography; Behavior, Animal; Brain; Cerebrovascular Circulation; Deoxyglucose; Dizocilpine Maleate; Ketamine; Male; Mice; Mice, Inbred ICR; Motor Activity | 2000 |
Morphine and amphetamine sensitization in rats demonstrated under moderate- and high-dose NMDA receptor blockade with MK-801 (dizocilpine).
Topics: Amphetamine; Animals; Bromocriptine; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 2000 |
NMDA glutamate receptor role in the development of context-dependent and independent sensitization of the induction of stereotypy by amphetamine or apomorphine.
Topics: Amphetamine; Animals; Apomorphine; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Environment; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indazoles; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Piperazines; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 2000 |
Generalisation of ethanol with drug mixtures containing a positive modulator of the GABA(A) receptor and an NMDA antagonist.
Topics: Amphetamine; Animals; Central Nervous System Depressants; Chlordiazepoxide; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Ethanol; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; Generalization, Stimulus; Male; Pentobarbital; Rats; Receptors, N-Methyl-D-Aspartate | 2001 |
Tryptamine derivatives as non-competitive N-methyl-D-aspartate receptor blockers: studies using [(3)H]MK-801 binding in rat hippocampal membranes.
Topics: Amphetamine; Animals; Binding, Competitive; Cell Membrane; Dentate Gyrus; Dizocilpine Maleate; Hippocampus; Kinetics; Male; Phenethylamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tritium; Tryptamines | 2000 |
NMDA antagonists block expression of sensitization of amphetamine- and apomorphine-induced stereotypy.
Topics: Amphetamine; Animals; Apomorphine; Arginine; Behavior, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indazoles; Male; Mice; Nitric Oxide Synthase; Piperazines; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 2000 |
Significance of glutamate and dopamine neurons in the ventral pallidum in the expression of behavioral sensitization to amphetamine.
Topics: Amphetamine; Animals; Aspartic Acid; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Globus Pallidus; Glutamic Acid; Male; Motor Activity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2001 |
Startle and sensorimotor gating in rats lacking CCK-A receptors.
Topics: Acoustic Stimulation; Amphetamine; Animals; Apomorphine; Brain; Cholecystokinin; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Motor Activity; Neural Inhibition; Rats; Rats, Inbred OLETF; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Reflex, Startle | 2001 |
Comparison of apomorphine, amphetamine and dizocilpine disruptions of prepulse inhibition in inbred and outbred mice strains.
Topics: Acoustic Stimulation; Amphetamine; Animals; Apomorphine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neural Inhibition; Neurotransmitter Agents; Reflex, Startle; Species Specificity | 2001 |
Blockade of subthalamic glutamatergic activity corrects changes in neuronal metabolism and motor behavior in rats with nigrostriatal lesions.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Energy Metabolism; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Male; Motor Activity; Neostriatum; Neural Pathways; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra; Subthalamic Nucleus; Succinate Dehydrogenase; Sympatholytics; Synaptic Transmission | 2001 |
Sensitization of prepulse inhibition deficits by repeated administration of dizocilpine.
Topics: Acoustic Stimulation; Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reflex, Startle | 2001 |
Effects of N-methyl-D-aspartate agonists and antagonists in rats discriminating amphetamine.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Central Nervous System Stimulants; Cycloserine; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2001 |
Cocaine and amphetamine depress striatal GABAergic synaptic transmission through D2 dopamine receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamine; Animals; Cocaine; Denervation; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; Neostriatum; Neural Pathways; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Dopamine D2; Synaptic Transmission | 2002 |
Effects of reversible inactivation of the neonatal ventral hippocampus on behavior in the adult rat.
Topics: Age Factors; Aging; Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Central Nervous System Stimulants; Cohort Studies; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Interpersonal Relations; Male; Microinjections; Motor Activity; Psychomotor Agitation; Rats; Rats, Sprague-Dawley; Schizophrenia; Tetrodotoxin | 2002 |
A single exposure to restraint stress induces behavioral and neurochemical sensitization to stimulating effects of amphetamine: involvement of NMDA receptors.
Topics: Amphetamine; Animals; Caudate Nucleus; Dizocilpine Maleate; Dopamine; Infusions, Parenteral; Male; Microdialysis; Microinjections; Motor Activity; Putamen; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Restraint, Physical | 2002 |
Distinct pattern of c-fos mRNA expression after systemic and intra-accumbens amphetamine and MK-801.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Injections, Intraperitoneal; Injections, Intraventricular; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2002 |
Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Dizocilpine Maleate; Dopamine Agonists; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Genotype; Heterozygote; Homozygote; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 2002 |
SR146131, a cholecystokinin-A receptor agonist, antagonizes prepulse inhibition deficits produced by dizocilpine and DOI.
Topics: Amphetamine; Amphetamines; Animals; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Indoles; Inhibition, Psychological; Male; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Reflex, Startle; Thiazoles | 2002 |
Decreased hyperlocomotion induced by MK-801, but not amphetamine and caffeine in mice lacking cellular prion protein (PrP(C)).
Topics: Amphetamine; Animals; Caffeine; Dizocilpine Maleate; Dopamine Agonists; Down-Regulation; Excitatory Amino Acid Antagonists; Female; Hyperkinesis; Male; Mental Disorders; Mice; Mice, Knockout; Motor Activity; PrPC Proteins; Receptors, Dopamine; Receptors, Glutamate; Receptors, Purinergic P1; Synaptic Transmission | 2002 |
GABA(A) alpha 1 subunit knock-out mice do not show a hyperlocomotor response following amphetamine or cocaine treatment.
Topics: Amphetamine; Animals; Benzazepines; Binding, Competitive; Central Nervous System Stimulants; Cocaine; Diazepam; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Modulators; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Protein Subunits; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Spiperone | 2003 |
Deficient prepulse inhibition of acoustic startle in Hooded-Wistar rats compared with Sprague-Dawley rats.
Topics: Acoustic Stimulation; Amphetamine; Animals; Anxiety; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Maze Learning; Motor Activity; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reflex, Startle; Schizophrenia; Species Specificity | 2003 |
Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia.
Topics: Amphetamine; Animals; Behavior, Animal; Calcineurin; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Schizophrenia; Signal Transduction; Social Behavior | 2003 |
Age-related differences in MK-801- and amphetamine-induced locomotor and stereotypic activities of rats.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Central Nervous System Stimulants; Dizocilpine Maleate; Male; Motor Activity; Rats; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Time Factors | 2003 |
Effect of riluzole on MK-801 and amphetamine-induced hyperlocomotion.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Hyperkinesis; Locomotion; Male; Mice; Neuroprotective Agents; Random Allocation; Riluzole | 2003 |
Reduced startle habituation and prepulse inhibition in mice lacking the adenosine A2A receptor.
Topics: Acoustic Stimulation; Amphetamine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Habituation, Psychophysiologic; Male; Mice; Mice, Knockout; Neural Inhibition; Receptor, Adenosine A2A; Receptors, Purinergic P1; Reflex, Startle; Sensory Thresholds | 2003 |
Motor effects of amphetamine in rats pretreated with either dizocilpine or phencyclidine.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Motor Activity; Movement; Phencyclidine; Rats; Stereotyped Behavior; Time Factors | 2003 |
Effects of ibotenate pedunculopontine tegmental nucleus lesions on exploratory behaviour in the open field.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Exploratory Behavior; Habituation, Psychophysiologic; Ibotenic Acid; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali | 2004 |
T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions.
Topics: Amphetamine; Animals; Brain-Derived Neurotrophic Factor; Cognition; Cognition Disorders; Dizocilpine Maleate; Enzyme-Linked Immunosorbent Assay; Glatiramer Acetate; Male; Maze Learning; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Peptides; Reflex, Startle; Schizophrenia; T-Lymphocytes; Vaccination | 2004 |
Prepulse inhibition of acoustic startle in spontaneously hypertensive rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Radiation; Excitatory Amino Acid Antagonists; Hypertension; Male; Neural Inhibition; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Reflex, Acoustic; Reflex, Startle; Serotonin Receptor Agonists; Species Specificity | 2004 |
Guanosine selectively inhibits locomotor stimulation induced by the NMDA antagonist dizocilpine.
Topics: Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Guanosine; Locomotion; Male; Maze Learning; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate | 2004 |
Prepulse inhibition in fawn-hooded rats: increased sensitivity to 5-HT1A receptor stimulation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Neural Inhibition; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reflex, Startle; Serotonin Receptor Agonists; Species Specificity | 2004 |
Increased locomotor response to amphetamine, but not other psychostimulants, in adult mice submitted to a low-protein diet.
Topics: Amphetamine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Diet; Dietary Proteins; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Protein-Energy Malnutrition; Purinergic P1 Receptor Antagonists; Receptors, N-Methyl-D-Aspartate | 2004 |
Behavioral sensitization due to social defeat stress in mice: antagonism at mGluR5 and NMDA receptors.
Topics: Amphetamine; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Prefrontal Cortex; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Ventral Tegmental Area | 2005 |
Comparative effects of NO-synthase inhibitor and NMDA antagonist on generation of nitric oxide and release of amino acids and acetylcholine in the rat brain elicited by amphetamine neurotoxicity.
Topics: Acetylcholine; Amino Acids; Amphetamine; Animals; Brain; Dizocilpine Maleate; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2004 |
Glutamate N-methyl-D-aspartate and dopamine receptors have contrasting effects on the limbic versus the somatosensory cortex with respect to amphetamine-induced neurodegeneration.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Limbic System; Male; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 2004 |
Reduced effects of amphetamine on prepulse inhibition of startle in gastrin-deficient mice.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Female; Gastrins; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Reflex, Startle | 2005 |
Effect of subchronic caffeine treatment on MK-801-induced changes in locomotion, cognition and ataxia in mice.
Topics: Adenosine; Amphetamine; Animals; Ataxia; Caffeine; Central Nervous System Stimulants; Cognition; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Humans; Locomotion; Male; Mice; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2005 |
Pleiotrophin gene transcription in the rat nucleus accumbens is stimulated by an acute dose of amphetamine.
Topics: Amphetamine; Analysis of Variance; Animals; Blotting, Northern; Carrier Proteins; Central Nervous System Stimulants; Cytokines; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2005 |
Neural cell adhesion molecule-secreting transgenic mice display abnormalities in GABAergic interneurons and alterations in behavior.
Topics: Amphetamine; Animals; Behavior, Animal; Blotting, Western; Cell Count; Central Nervous System Stimulants; Conditioning, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fear; Fluorescent Antibody Technique; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; Interneurons; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Cell Adhesion Molecules; Neural Inhibition; Staining and Labeling; Synaptophysin | 2005 |
Cinnarizine has an atypical antipsychotic profile in animal models of psychosis.
Topics: Amphetamine; Animals; Antipsychotic Agents; Calcium Channel Blockers; Catalepsy; Central Nervous System Stimulants; Cinnarizine; Dizocilpine Maleate; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Haloperidol; Hyperkinesis; Male; Mice; Motor Activity; Psychotic Disorders | 2005 |
Enhanced effect of dopaminergic stimulation on prepulse inhibition in mice deficient in the alpha subunit of G(z).
Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Dizocilpine Maleate; Dopamine; GTP-Binding Protein alpha Subunits; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Receptors, Dopamine D1; Receptors, Dopamine D2; Reflex, Startle | 2005 |
Early maternal deprivation retards neurodevelopment in Wistar rats.
Topics: Amphetamine; Animals; Animals, Newborn; Body Weight; Dizocilpine Maleate; Eye Abnormalities; Female; Male; Maternal Deprivation; Motor Activity; Nervous System; Neural Inhibition; Rats; Rats, Wistar | 2005 |
Nitrous oxide and xenon prevent amphetamine-induced carrier-mediated dopamine release in a memantine-like fashion and protect against behavioral sensitization.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Memantine; Motor Activity; Nitrous Oxide; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors; Xenon | 2006 |
Role of glutamate and dopamine receptors in the psychopharmacological profile of the indole alkaloid psychollatine.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Brazil; Chlorpromazine; Diazepam; Dizocilpine Maleate; Glycosides; Indole Alkaloids; Male; Memory; Mice; Models, Biological; Molecular Structure; Plants, Medicinal; Psychopharmacology; Psychotria; Receptors, Dopamine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Receptor Agonists | 2006 |
A glutamate-dopamine interaction in the persistent enhanced response to amphetamine in nucleus accumbens core but not shell following a single restraint stress.
Topics: Amphetamine; Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological | 2007 |
A simple webcam-based approach for the measurement of rodent locomotion and other behavioural parameters.
Topics: Algorithms; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dizocilpine Maleate; Evaluation Studies as Topic; Excitatory Amino Acid Antagonists; Exploratory Behavior; Locomotion; Mice; Mice, Inbred C57BL; Reproducibility of Results; Rodentia; Sensitivity and Specificity; Software; Time Factors; Video Recording | 2006 |
Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: evidence for altered striatal function.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Biogenic Monoamines; Brain; Central Nervous System Stimulants; Conditioning, Operant; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Maze Learning; Methamphetamine; Mice; Mice, Knockout; Motor Activity; Phencyclidine; Phosphoric Diester Hydrolases | 2006 |
Beta-amyloid treatment sensitizes mice to amphetamine-induced locomotion but reduces response to caffeine.
Topics: Adenosine; Adrenergic Agents; Alzheimer Disease; Amphetamine; Amyloid beta-Peptides; Animals; Avoidance Learning; Brain; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Glutamine; Injections, Intraventricular; Male; Mice; Motor Activity; Psychotic Disorders | 2004 |
ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Brain Chemistry; Catalepsy; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Haloperidol; Head Movements; Male; Mice; Mice, Inbred Strains; Motor Activity; Piperidines; Prolactin; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Urea | 2007 |
Post-pubertal emergence of alterations in locomotor activity in stop null mice.
Topics: Aging; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Mice; Mice, Knockout; Microtubule-Associated Proteins; Motor Activity | 2007 |
Repeated treatment with the NMDA antagonist MK-801 disrupts reconsolidation of memory for amphetamine-conditioned place preference.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Dizocilpine Maleate; Male; Memory; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2007 |
Transgenic overexpression of adenosine kinase in brain leads to multiple learning impairments and altered sensitivity to psychomimetic drugs.
Topics: Adenosine Kinase; Amphetamine; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Conditioning, Classical; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Exploratory Behavior; Freezing Reaction, Cataleptic; Learning Disabilities; Maze Learning; Memory; Mice; Mice, Transgenic; Psychomotor Performance; Spatial Behavior | 2007 |
Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Catalepsy; Central Nervous System Stimulants; Cocaine; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Partial Agonism; Excitatory Amino Acid Antagonists; Glutamine; Haloperidol; Hyperkinesis; Ketamine; Locomotion; Male; Mice; Motor Activity; Piperazines; Quinolones; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Time Factors | 2008 |
Does angiotensin interact with dopaminergic mechanisms in the brain to modulate prepulse inhibition in mice?
Topics: Amphetamine; Angiotensins; Animals; Apomorphine; Brain Chemistry; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Enhancer Elements, Genetic; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Knockout; Mice, Transgenic; Phosphopyruvate Hydratase; Receptor, Angiotensin, Type 1; Reflex, Startle; Renin | 2008 |
Behavioral characterization of mice deficient in the phosphodiesterase-10A (PDE10A) enzyme on a C57/Bl6N congenic background.
Topics: Amphetamine; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Depression; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Hot Temperature; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nucleotides, Cyclic; Pain Measurement; Phencyclidine; Phosphoproteins; Phosphoric Diester Hydrolases; Serotonin; Swimming | 2008 |
Antipsychotic-like behavioral effects and cognitive enhancement by a potent and selective muscarinic M-sub-1 receptor agonist, AC-260584.
Topics: Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Benzoxazines; Cognition; Dizocilpine Maleate; Drug Interactions; Hyperkinesis; Locomotion; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Nootropic Agents; Reaction Time; Space Perception; Tacrine | 2008 |
Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Cyclopentanes; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Routes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Frontal Lobe; Hyperkinesis; In Vitro Techniques; Male; Mice; Motor Activity; Psychotic Disorders; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Metabotropic Glutamate; Tricarboxylic Acids | 2008 |
Prenatal protein deprivation alters dopamine-mediated behaviors and dopaminergic and glutamatergic receptor binding.
Topics: Age Factors; Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Female; Haloperidol; Locomotion; Male; Pregnancy; Prenatal Nutritional Physiological Phenomena; Protein Binding; Protein Deficiency; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Glutamate; Sex Factors | 2008 |
Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Benzamides; Central Nervous System Stimulants; Cognition; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Nitroarginine; Piperidines; Rats; Rats, Wistar; Reflex, Startle; Schizophrenia; Schizophrenic Psychology | 2009 |
Subchronic MK-801 behavioural deficits in rats: partial reversal by the novel nitrate GT 1061.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Chlormethiazole; Cognition Disorders; Data Interpretation, Statistical; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Male; Maze Learning; Motor Activity; Nitrates; Rats; Rats, Sprague-Dawley; Reversal Learning | 2009 |
D-aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801.
Topics: Acoustic Stimulation; Amphetamine; Animals; Brain; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; D-Aspartate Oxidase; D-Aspartic Acid; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Hippocampus; Long-Term Synaptic Depression; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Synaptic Transmission; Tissue Distribution | 2008 |
CB1 receptor knockout mice are hyporesponsive to the behavior-stimulating actions of d-amphetamine: role of mGlu5 receptors.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Hyperkinesis; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Motor Activity; Nucleus Accumbens; Piperidines; Pyrazoles; Pyridines; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Rimonabant | 2009 |
Sensitization to amphetamine occurs simultaneously at immune level and in met-enkephalin of the nucleus accumbens and spleen: an involved NMDA glutamatergic mechanism.
Topics: Amphetamine; Analysis of Variance; Animals; Cell Proliferation; Cells, Cultured; Central Nervous System Stimulants; Dizocilpine Maleate; Drug Administration Schedule; Enkephalin, Methionine; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Nucleus Accumbens; Radioimmunoassay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spleen; Time Factors | 2009 |
Sensorimotor gating in neurotensin-1 receptor null mice.
Topics: Acoustic Stimulation; Adamantane; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Indoles; Mice; Mice, Knockout; Neural Inhibition; Neuroprotective Agents; Receptors, Neurotensin; Reflex, Startle; Sensory Gating | 2010 |
Combined administration of an mGlu2/3 receptor agonist and a 5-HT 2A receptor antagonist markedly attenuate the psychomotor-activating and neurochemical effects of psychostimulants.
Topics: Amino Acids; Amphetamine; Animals; Antipsychotic Agents; Dizocilpine Maleate; Dopamine; Drug Synergism; Drug Therapy, Combination; Excitatory Amino Acid Agonists; Fluorobenzenes; Male; Motor Activity; Norepinephrine; Nucleus Accumbens; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Metabotropic Glutamate; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2009 |
The glycine transporter-1 inhibitor SSR103800 displays a selective and specific antipsychotic-like profile in normal and transgenic mice.
Topics: Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Aripiprazole; Catalepsy; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Plasma Membrane Transport Proteins; Glycine Plasma Membrane Transport Proteins; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Piperazines; Quinolones; Receptors, N-Methyl-D-Aspartate | 2010 |
Pitx3-deficient aphakia mice display unique behavioral responses to psychostimulant and antipsychotic drugs.
Topics: Amphetamine; Analysis of Variance; Animals; Aphakia; Apomorphine; Behavior, Animal; Catalepsy; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agents; Excitatory Amino Acid Antagonists; Homeodomain Proteins; Mice; Mice, Knockout; Motor Activity; Neurons; Time Factors; Transcription Factors | 2010 |
Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.
Topics: Age Factors; Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain; Carrier Proteins; Chromatography, High Pressure Liquid; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Electrochemical Techniques; Embryo, Mammalian; Exploratory Behavior; Female; Gene Expression Regulation, Developmental; Humans; Locomotion; Magnetic Resonance Imaging; Male; Maze Learning; Mental Disorders; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Parvalbumins; Phenotype; Pregnancy; Silver Staining | 2011 |
Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD.
Topics: Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Casein Kinase Idelta; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Antagonists; Locomotion; Methylphenidate; Mice; Prosencephalon; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2010 |
Subchronic MK-801 treatment and post-weaning social isolation in rats: differential effects on locomotor activity and hippocampal long-term potentiation.
Topics: Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Central Nervous System Stimulants; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; Hippocampus; Long-Term Potentiation; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Social Isolation; Time Factors | 2010 |
Interaction of glutathione depletion and psychotropic drug treatment in prepulse inhibition in rats and mice.
Topics: Acoustic Stimulation; Amphetamine; Animals; Brain Chemistry; Cyclohexanones; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Glutathione; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C57BL; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Reflex, Startle; Sensory Gating | 2010 |
The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors.
Topics: Aconitine; Amphetamine; Animals; Behavior, Animal; Benzazepines; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Female; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Varenicline | 2011 |
T-type calcium channel antagonism produces antipsychotic-like effects and reduces stimulant-induced glutamate release in the nucleus accumbens of rats.
Topics: Amphetamine; Animals; Antipsychotic Agents; Benzeneacetamides; Calcium Channel Blockers; Calcium Channels, T-Type; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Male; Motor Activity; Nucleus Accumbens; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2012 |
The M₁/M₄ preferring agonist xanomeline reverses amphetamine-, MK801- and scopolamine-induced abnormalities of latent inhibition: putative efficacy against positive, negative and cognitive symptoms in schizophrenia.
Topics: Amphetamine; Animals; Antimanic Agents; Behavior, Animal; Cognition Disorders; Dizocilpine Maleate; Dose-Response Relationship, Drug; Kinetics; Male; Molecular Targeted Therapy; Muscarinic Agonists; Neural Inhibition; Neurotransmitter Agents; Pyridines; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Scopolamine; Tachyphylaxis; Thiadiazoles | 2011 |
Individual differences in maternal response to immune challenge predict offspring behavior: contribution of environmental factors.
Topics: Age Factors; Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Antiviral Agents; Behavior, Animal; Body Weight; Central Nervous System Stimulants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Individuality; Locomotion; Male; Poly I-C; Predictive Value of Tests; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Weight Gain; Weight Loss | 2011 |
Impulsive action induced by amphetamine, cocaine and MK801 is reduced by 5-HT(2C) receptor stimulation and 5-HT(2A) receptor blockade.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethylamines; Excitatory Amino Acid Antagonists; Fluorobenzenes; Impulsive Behavior; Indoles; Male; Piperidines; Psychomotor Performance; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2011 |
The discriminative stimulus effects of midazolam are resistant to modulation by morphine, amphetamine, dizocilpine, and γ-butyrolactone in rhesus monkeys.
Topics: 4-Butyrolactone; Amphetamine; Animals; Codependency, Psychological; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Midazolam; Morphine; Reinforcement, Psychology; Substance-Related Disorders; Time Factors | 2011 |
Vglut2 haploinsufficiency enhances behavioral sensitivity to MK-801 and amphetamine in mice.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Female; Haploinsufficiency; Hyperkinesis; Mice; Mice, Mutant Strains; Motor Activity; Schizophrenia; Sensory Gating; Vesicular Glutamate Transport Protein 2 | 2011 |
The α₂-adrenergic antagonist idazoxan counteracts prepulse inhibition deficits caused by amphetamine or dizocilpine in rats.
Topics: Acoustic Stimulation; Adrenergic alpha-2 Receptor Antagonists; Amphetamine; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Female; Idazoxan; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex, Startle | 2012 |
Reversal of oxidative stress by histamine H₃ receptor-ligands in experimental models of schizophrenia.
Topics: Amphetamine; Animals; Antioxidants; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain Chemistry; Catalase; Catalepsy; Central Nervous System Stimulants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutathione; Haloperidol; Histamine H3 Antagonists; Male; Mice; Motor Activity; Oxidative Stress; Rats; Schizophrenia; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Neuroanatomy and psychomimetic-induced locomotion in C57BL/6J and 129/X1SvJ mice exposed to developmental vitamin D deficiency.
Topics: Amphetamine; Animals; Animals, Newborn; Brain; Disease Models, Animal; Dizocilpine Maleate; Female; Locomotion; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred Strains; Neuroanatomy; Pregnancy; Psychotropic Drugs; Sex Factors; Species Specificity; Vitamin D Deficiency | 2012 |
Differential effects of the antidepressant mirtazapine on amphetamine- and dizocilpine-induced PPI deficits.
Topics: Acoustic Stimulation; Amphetamine; Animals; Antidepressive Agents; Dizocilpine Maleate; Female; Inhibition, Psychological; Mianserin; Mirtazapine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Sensory Gating | 2012 |
Prenatal immune challenge in rats: altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route-based learning as a function of maternal body weight gain after prenatal exposure to poly IC.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Female; Learning; Male; Maternal Exposure; Maze Learning; Motor Activity; Neuropsychological Tests; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reflex, Startle; Weight Gain | 2012 |
Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion.
Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Astrocytes; Brain; Cell Line, Transformed; Cycloheximide; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Glial Fibrillary Acidic Protein; Humans; Inhibition, Psychological; Leupeptins; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Racemases and Epimerases; Reflex, Startle; Schizophrenia; Serine; Transfection | 2013 |
Spontaneous polydipsia in animals treated subchronically with MK-801.
Topics: Age Factors; Amphetamine; Animals; Animals, Newborn; Body Weight; Central Nervous System Stimulants; Cognition Disorders; Cohort Studies; Disease Models, Animal; Dizocilpine Maleate; Drinking; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Food Deprivation; Male; Motor Activity; Polydipsia; Random Allocation; Rats; Rats, Sprague-Dawley | 2013 |
Adult vitamin D deficiency leads to behavioural and brain neurochemical alterations in C57BL/6J and BALB/c mice.
Topics: Amphetamine; Animals; Behavior, Animal; Brain; Catechol O-Methyltransferase; Catecholamines; Diet; Dizocilpine Maleate; Exploratory Behavior; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Monoamine Oxidase; Motor Activity; Social Behavior; Synaptic Transmission; Vitamin D Deficiency | 2013 |
Effects of MK-801 and amphetamine treatments on allergic lung inflammatory response in mice.
Topics: Amphetamine; Animals; Bone Marrow Cells; Bronchoalveolar Lavage Fluid; Cell Degranulation; Chemotaxis, Leukocyte; Corticosterone; Disease Models, Animal; Dizocilpine Maleate; Interleukins; Leukocyte Count; Male; Mast Cells; Mice; Mice, Inbred BALB C; Ovalbumin; Pneumonia; Receptors, N-Methyl-D-Aspartate; Respiratory Hypersensitivity | 2013 |
The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodents.
Topics: Allosteric Regulation; Amphetamine; Anilides; Animals; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Hyperkinesis; Male; Mice; Motor Activity; Rats; Receptors, Metabotropic Glutamate; Schizophrenia | 2013 |
GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Functional Laterality; GABA-A Receptor Agonists; Homovanillic Acid; Male; Medial Forebrain Bundle; Mental Disorders; Muscimol; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Receptors, GABA-A; Statistics, Nonparametric; Subthalamic Nucleus; Time Factors | 2013 |
Chronic intermittent toluene inhalation in adolescent rats alters behavioural responses to amphetamine and MK801.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Solvents; Substance-Related Disorders; Time Factors; Toluene; Weight Gain | 2014 |
The impact of adult vitamin D deficiency on behaviour and brain function in male Sprague-Dawley rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Choice Behavior; Corpus Striatum; Dizocilpine Maleate; gamma-Aminobutyric Acid; Helplessness, Learned; Male; Motor Activity; Prefrontal Cortex; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Reaction Time; Social Behavior; Vitamin D Deficiency | 2013 |
Synergistic activity between the delta-opioid agonist SNC80 and amphetamine occurs via a glutamatergic NMDA-receptor dependent mechanism.
Topics: Amphetamine; Analgesics, Opioid; Animals; Benzamides; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Drug Synergism; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta | 2014 |
Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism.
Topics: Amphetamine; Animals; Autistic Disorder; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Locomotion; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Nerve Tissue Proteins; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Reflex, Startle; Signal Transduction; Smell; Species Specificity; Stereotyped Behavior | 2014 |
A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia.
Topics: Alanine; Amphetamine; Animals; Antipsychotic Agents; Anxiety; Benzodiazepines; Brain; Central Nervous System Stimulants; Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Olanzapine; Phencyclidine; Psychomotor Agitation; Schizophrenia; Social Behavior | 2014 |
Effects of amphetamine exposure in adolescence or young adulthood on inhibitory control in adult male and female rats.
Topics: Age Factors; Amphetamine; Animals; Arousal; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Impulsive Behavior; Inhibition, Psychological; Learning; Male; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sex Factors; Task Performance and Analysis | 2014 |
MK-801 and amphetamine result in dissociable profiles of cognitive impairment in a rodent paired associates learning task with relevance for schizophrenia.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Cognition Disorders; Dizocilpine Maleate; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Paired-Associate Learning; Psychomotor Performance; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenic Psychology | 2015 |
Role of nicotinic receptors in the lateral habenula in the attenuation of amphetamine-induced prepulse inhibition deficits of the acoustic startle response in rats.
Topics: Acoustic Stimulation; Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Female; Habenula; Haloperidol; Mecamylamine; Nicotine; Prepulse Inhibition; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reflex, Startle; Sensory Gating | 2015 |
Mice Lacking the Serotonin Htr2B Receptor Gene Present an Antipsychotic-Sensitive Schizophrenic-Like Phenotype.
Topics: Amphetamine; Animals; Antipsychotic Agents; Cohort Studies; Conditioning, Psychological; Cues; Disease Models, Animal; Dizocilpine Maleate; Fear; Inhibition, Psychological; Male; Mice; Mice, Transgenic; Motor Activity; Receptor, Serotonin, 5-HT2B; Recognition, Psychology; Schizophrenia; Sensory Gating; Social Behavior; Wakefulness | 2015 |
Involvement of Glutamate NMDA Receptors in the Acute, Long-Term, and Conditioned Effects of Amphetamine on Rat 50 kHz Ultrasonic Vocalizations.
Topics: Amphetamine; Animals; Brain; Central Nervous System Stimulants; Conditioning, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Excitatory Amino Acid Antagonists; Male; Motor Activity; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Ultrasonics; Vocalization, Animal | 2015 |
Negative modulation of α₅ GABAA receptors in rats may partially prevent memory impairment induced by MK-801, but not amphetamine- or MK-801-elicited hyperlocomotion.
Topics: Amphetamine; Animals; Behavior, Animal; Benzodiazepines; Cognition Disorders; Dizocilpine Maleate; Hyperkinesis; Male; Maze Learning; Memory Disorders; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2015 |
Nucleus accumbens NMDA receptor activation regulates amphetamine cross-sensitization and deltaFosB expression following sexual experience in male rats.
Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Male; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Reaction Time; Receptors, N-Methyl-D-Aspartate; Reward; Sexual Behavior, Animal | 2016 |
Signaling Mechanisms in the Nitric Oxide Donor- and Amphetamine-Induced Dopamine Release in Mesencephalic Primary Cultured Neurons.
Topics: Amphetamine; Animals; Calcium Channel Blockers; Cells, Cultured; Dizocilpine Maleate; Dopamine; Embryo, Mammalian; Female; Mesencephalon; Neurons; Neuroprotective Agents; Nifedipine; Nitric Oxide Donors; Nitrites; Nitroso Compounds; Pregnancy; Rats; Rats, Wistar; Signal Transduction; Time Factors | 2016 |
Involvement of GABAB Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu4 Receptor, LSP4-2022.
Topics: Amphetamine; Animals; Antipsychotic Agents; Cyclopentanes; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Excitatory Amino Acid Agonists; GABA Agents; Male; Mice, Knockout; Motor Activity; Phosphinic Acids; Pyrimidines; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Recognition, Psychology; Schizophrenia; Social Behavior | 2016 |
Preventive effects of minocycline in a neurodevelopmental two-hit model with relevance to schizophrenia.
Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hippocampus; Interferon Inducers; Interleukin-1beta; Mice; Microglia; Minocycline; Poly I-C; Prefrontal Cortex; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Psychoses, Substance-Induced; Schizophrenia; Stress, Psychological | 2016 |
Memantine improves memory impairment and depressive-like behavior induced by amphetamine withdrawal in rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Antidepressive Agents; Central Nervous System Stimulants; Depression; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Imipramine; Male; Memantine; Memory Disorders; Muscarinic Antagonists; Nootropic Agents; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Scopolamine; Substance Withdrawal Syndrome | 2016 |
NMDA receptors are involved in the antidepressant-like effects of capsaicin following amphetamine withdrawal in male mice.
Topics: Amphetamine; Animals; Antidepressive Agents; Capsaicin; Central Nervous System Stimulants; Depressive Disorder; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Time Factors; TRPV Cation Channels | 2016 |
Stimulant drug effects on touchscreen automated paired-associates learning (PAL) in rats.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Methylphenidate; Modafinil; Nootropic Agents; Paired-Associate Learning; Rats; Wakefulness-Promoting Agents | 2016 |
The neurotoxic mechanisms of amphetamine: Step by step for striatal dopamine depletion.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Corpus Striatum; Dextroamphetamine; Dizocilpine Maleate; Dopamine; Male; Neurotoxicity Syndromes; Niacinamide; Rats, Sprague-Dawley | 2017 |
Effects of chronic prenatal MK-801 treatment on object recognition, cognitive flexibility, and drug-induced locomotor activity in juvenile and adult rat offspring.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cognition; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Executive Function; Female; Learning; Male; Memory; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Schizophrenic Psychology | 2017 |
Cortical high gamma network oscillations and connectivity: a translational index for antipsychotics to normalize aberrant neurophysiological activity.
Topics: Amphetamine; Animals; Antipsychotic Agents; Benzodiazepines; Brain Waves; Central Nervous System Stimulants; Cerebral Cortex; Clozapine; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Nerve Net; Olanzapine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Risperidone | 2017 |
Involvement of NO/NMDA-R pathway in the behavioral despair induced by amphetamine withdrawal.
Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Locomotion; Male; Mice; Motivation; Neuroprotective Agents; Nitrites; Signal Transduction; Substance Withdrawal Syndrome; Swimming | 2018 |
The role of striatum and prefrontal cortex in the prevention of amphetamine-induced schizophrenia-like effects mediated by nitric oxide compounds.
Topics: Amphetamine; Animals; Antipsychotic Agents; Corpus Striatum; Cyclic AMP; Dizocilpine Maleate; Male; Mice; Motor Activity; Nitric Oxide; Nitric Oxide Donors; Prefrontal Cortex; Prepulse Inhibition; Schizophrenia | 2018 |
Mutual activation of glutamatergic mGlu
Topics: Amphetamine; Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Male; Mice; Motor Activity; Phosphinic Acids; Receptor, Muscarinic M4; Receptors, Metabotropic Glutamate; Rodentia; Schizophrenia | 2018 |
Modulating inhibitory response control through potentiation of GluN2D subunit-containing NMDA receptors.
Topics: Allosteric Regulation; Amphetamine; Animals; Behavior, Animal; Dizocilpine Maleate; Locomotion; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2020 |
Potential antipsychotic action of the selective agonist of adenosine A1 receptors, 5'-Cl-5'-deoxy-ENBA, in amphetamine and MK-801 rat models.
Topics: Adenosine A1 Receptor Agonists; Amphetamine; Animals; Antipsychotic Agents; Dizocilpine Maleate; Locomotion; Male; Motor Activity; Rats; Rats, Wistar; Receptor, Adenosine A1 | 2020 |
Pentadecapeptide BPC 157 counteracts L-NAME-induced catalepsy. BPC 157, L-NAME, L-arginine, NO-relation, in the suited rat acute and chronic models resembling 'positive-like' symptoms of schizophrenia.
Topics: Amphetamine; Animals; Apomorphine; Arginine; Behavior, Animal; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Enzyme Inhibitors; Haloperidol; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Proteins; Rats; Rats, Wistar; Schizophrenia | 2021 |
Prepulse inhibition based grouping of rats and assessing differences in response to pharmacological agents.
Topics: Acoustic Stimulation; Amphetamine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Cholinergic Antagonists; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Nicotine; Nicotinic Agonists; Prepulse Inhibition; Rats; Rats, Sprague-Dawley; Reflex, Startle; Scopolamine | 2021 |
Cannabidiol prevents disruptions in sensorimotor gating induced by psychotomimetic drugs that last for 24-h with probable involvement of epigenetic changes in the ventral striatum.
Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Cannabidiol; Clozapine; Dizocilpine Maleate; DNA Methylation; Epigenesis, Genetic; Hallucinogens; Male; Mice; Neuroprotective Agents; Prefrontal Cortex; Prepulse Inhibition; Reflex, Startle; Schizophrenia; Sensory Gating; Time Factors; Ventral Striatum | 2021 |
How do zebrafish (Danio rerio) respond to MK-801 and amphetamine? Relevance for assessing schizophrenia-related endophenotypes in alternative model organisms.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Endophenotypes; Female; Male; Mice; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Zebrafish | 2021 |
Antipsychotic- and Anxiolytic-like Properties of a Multimodal Compound JJGW08 in Rodents.
Topics: Amphetamine; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Catalepsy; Dizocilpine Maleate; Dopamine; Mice; Rats; Rodentia; Serotonin | 2022 |
Dopaminergic and glutamatergic models of psychosis show differential sensitivity to aripiprazole and a novel experimental compound modulating D
Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Psychotic Disorders; Quinolones; Rats; Receptors, Serotonin | 2023 |