Compounds > amphetamine

amphetamine and clozapine

amphetamine has been researched along with clozapine in 96 studies

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-199023 (23.96)18.7374
1990's19 (19.79)18.2507
2000's32 (33.33)29.6817
2010's19 (19.79)24.3611
2020's3 (3.13)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lassen, JB1
Marsden, CD; Pycock, CJ; Tarsy, D1
Altier, H; Monti, JM; Souto, M1
Arushanian, EB; Tolpyshev, BA1
Korf, J; Westerink, BH1
Fielding, S; Lal, H; Marky, M1
Fog, R1
Belknap, JK; de Paulis, T; Janowsky, A; Kinzie, JM; Neve, KA; Taylor, B1
Ghidoni, R; Haselhorst, U; Schenk, H1
Mott, J; Sherman, AD1
Johnson, KM; Snell, LD1
el Mestikawy, S; Glowinski, J; Hamon, M1
Ramirez, OA; Wang, RY1
Krähling, H; Ruhland, M; Schmidt, WJ1
Compton, DR; Johnson, KM1
Arbilla, S; Baud, P; Langer, SZ1
Hoffmann, WE; Piercey, MF; Travis, M; Vogelsang, GD1
Dews, PB; Lehr, E; Morse, WH1
Biazzi, A; Fregnan, GB1
Likhosherstov, AM; Rayevskii, KS; Röhnert, H; Rostock, A; Rüger, C; Skoldinov, AP; Stavrovskaja, AW1
Nobrega, JN; Wiener, NI1
De Feo, G; Lisciani, R; Pavan, L; Samarelli, M; Valeri, P1
Brugge, K; McPherson, FA; Peirson, EE; Rebec, GV1
Arushanian, EB; Smirnova, LE; Tolpyshev, BA1
Donovan, H; Hoffman, DC1
Bervoets, K; Maurel-Remy, S; Millan, MJ1
Kenyon, P; Moore, S1
Clemens, AJ; Pierce, RC; Rebec, GV; Shapiro, LA1
Goldstein, JM; Litwin, LC; Malick, JB; Sutton, EB1
Papanikolaou, A; Salamone, JD; Sokolowski, JD; Steinpreis, RE1
Ewing, FE; Furman, JS; Howard, HR; Jackson, E; Johnson, C; Lowe, JA; Maloney, PR; Morrone, J; Newman, ME; Robinson, GL; Schmidt, AW; Seeger, TF; Seymour, PA; Zorn, SH1
Rebec, GV; Wang, Z1
Fox, DA; Shulman, LM1
Cooper, BR; Cox, RF; Durcan, MJ; Gengo, PJ; Jones-Humble, SA; Lyerly, D; Morgan, PF; Norton, RM; Russell, AV; Tang, FL; Wang, CM; Watson, MJ1
Rasmussen, K; Stockton, ME1
Arnt, J1
Bardgett, ME; Csernansky, JG; Jackson, JL; Taylor, BM1
Feldpaush, DL; Meng, ZH; Merchant, KM1
Adler, CM; Breier, A; Elman, I; Malhotra, AK; Pickar, D; Su, TP; Weisenfeld, NI1
Dadmarz, M; Ufer, M; Vogel, WH1
Gerlach, J; Peacock, L1
Audinot, V; Brocco, M; Dekeyne, A; Despaux, N; Maiofiss, L; Millan, MJ; Newman-Tancredi, A; Peglion, JL; Queriaux, S; Rivet, JM1
Dai, J; Guan, HJ; Zhu, XZ1
Cilia, J; Hagan, JJ; Piper, DC; Upton, N1
Bruhwyler, J; Cools, AR; Ellenbroek, BA; Liégeois, JF1
Feldon, J; Murphy, CA; Russig, H1
Bubser, M; Deutch, AY; Fadel, J1
Brodbeck, R; He, X; Hoffman, D; Kieltyka, A; Primus, R; Thurkauf, A; Wasley, JW; Zhao, H1
Bucan, M; Fetsko, LA; Hranilovic, D; Wang, Y; Xu, R1
Herman, ZS; Obuchowicz, E1
Rimmerman, N; Weiner, I; Zuckerman, L1
Nachman, R; Rehavi, M; Weiner, I; Zuckerman, L1
Feldon, J; Kovacevic, A; Murphy, CA; Russig, H1
Markou, A; Semenova, S1
Joy, B; McMahon, RP; Shepard, PD1
Carlson, PJ; Merlock, MC; Suppes, T1
Fletcher, PJ; Kapur, S; Tenn, CC1
Deitemeyer, N; Dobner, PR; Egnatashvili, V; Kinkead, B; Murray, T; Nemeroff, CB1
Alimohamad, H; Mouyal, J; Rajakumar, N; Rushlow, WJ; Sutton, L1
Kruse, CG; McCreary, AC; Olijslagers, JE; Perlstein, B; Siarey, R; Wadman, WJ; Werkman, TR1
Gizerian, SS; Grobin, AC; Lieberman, JA; Moy, SS1
Ko, F; Seeman, P; Tallerico, T1
Bortolato, M; Carta, M; Collu, M; Fadda, F; Frau, R; Mereu, G; Orrù, M; Stancampiano, R1
Crabbe, JC; Philibin, SD; Porter, JH; Vunck, SA; Walentiny, DM1
Barlow, KB; Kapur, S; Natesan, S; Nobrega, JN; Reckless, GE1
Gozes, I; Malkoff, A; Rehavi, M; Weizman, A1
Feldon, J; Meyer, U; Schwarz, MJ; Spoerri, E; Yee, BK1
Hu, G; Li, M; Sun, T1
Feldon, J; Singer, P; Yee, BK1
Arancio, O; Balsam, P; Chuhma, N; Conjard-Duplany, A; Fairhurst, S; Gaisler-Salomon, I; Galloway, MP; Ghoddoussi, F; Hen, R; Lee, S; Lewandowski, N; Masson, J; Miller, GM; Moore, HM; Rayport, S; Small, SA; Wang, Y; Zhang, H1
Alexander, KS; Brooks, JM; Bruno, JP; Sarter, M1
Assaf, Y; Piontkewitz, Y; Weiner, I1
Avenet, P; Bergis, O; Boulay, D; Griebel, G1
Boules, M; Briody, S; Fauq, I; Oliveros, A; Richelson, E1
Lipina, T; Roder, J1
Arad, M; Weiner, I1
Basta-Kaim, A; Budziszewska, B; Fijał, K; Kubera, M; Lasoń, W; Leśkiewicz, M; Regulska, M; Wędzony, K1
Dong, Y; Eskenazi, D; Ferguson, SM; Ishikawa, M; Neumaier, JF; Phillips, PE; Roth, BL; Wanat, MJ1
Figueredo, VM1
Abílio, VC; Calzavara, MB; Levin, R; Medrano, WA; Niigaki, ST; Santos, CM1
Li, M; Mead, A; Sun, T1
Calakos, N; Caron, MG; Daigle, TL; Farrell, MS; Guettier, JM; Huang, XP; Hufeisen, SJ; Lee, HM; Moy, SS; Nonneman, RJ; Pei, Y; Roth, BL; Sciaky, N; Simmons, A; Urban, DJ; Wan, Y; Wess, J; Yadav, PN1
Casanova, JP; Escobar, F; Fuentealba, JA; Gatica, RI; Herrera, AS1
Hacksell, U; Hubbard, D; McFarland, K1
Baune, BT; Greenberg, Z; Jaehne, EJ; Kabbara, S; Lopez, A; McCarthy, P; McClure, B; Parish, C; Ramshaw, H; Saleh, E; Schwarz, Q; van den Buuse, M; Wang, TY; Wiszniak, S; Woodcock, J; Xu, X1
Adan, RA; Beloate, LN; Coolen, LM; Omrani, A; Webb, IC1
Ahnaou, A; Drinkenburg, WHIM; Huysmans, H; Van de Casteele, T1
Crippa, JAS; Del Bel, E; Guimarães, FS; Joca, SRL; Pedrazzi, JFC; Sales, AJ1
Bousman, CA; Danilewitz, M; Frankow, L; Honer, WG; Mahmood, H; Mathew, N; Poonia, S; Rafizadeh, R; Schütz, CG1
Chohan, MO; Fein, H; Mirro, S; O'Reilly, KC; Veenstra-VanderWeele, J1

Reviews

2 review(s) available for amphetamine and clozapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Chemical cardiomyopathies: the negative effects of medications and nonprescribed drugs on the heart.
    The American journal of medicine, 2011, Volume: 124, Issue:6

    Topics: Amphetamine; Anabolic Agents; Anthracyclines; Antineoplastic Agents; Cardiomyopathies; Chloroquine; Clozapine; Cocaine; Doxorubicin; Ephedra; Ethanol; Heart; Humans; Methylphenidate; Nonprescription Drugs; Prescription Drugs; Testosterone

2011

Trials

2 trial(s) available for amphetamine and clozapine

ArticleYear
Effects of atypical antipsychotic drug treatment on amphetamine-induced striatal dopamine release in patients with psychotic disorders.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:4

    Topics: Adult; Amphetamine; Antipsychotic Agents; Clozapine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Neostriatum; Psychotic Disorders; Raclopride; Risperidone; Salicylamides; Tomography, Emission-Computed

1999
Adjunctive stimulant use in patients with bipolar disorder: treatment of residual depression and sedation.
    Bipolar disorders, 2004, Volume: 6, Issue:5

    Topics: Adult; Aged; Amphetamine; Antipsychotic Agents; Bipolar Disorder; Central Nervous System Stimulants; Clozapine; Consciousness Disorders; Depression; Diagnostic and Statistical Manual of Mental Disorders; Drug Therapy, Combination; Female; Humans; Male; Methylphenidate; Middle Aged; Retrospective Studies

2004

Other Studies

92 other study(ies) available for amphetamine and clozapine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Evidence for a noradrenergic mechanism in the grooming produced by (+)-amphetamine and 4, alpha-dimethyl-m-tyramine (H 77/77) in rats.
    Psychopharmacology, 1977, Oct-20, Volume: 54, Issue:2

    Topics: Amphetamine; Animals; Butyrophenones; Clozapine; Diazepam; Diphenhydramine; Grooming; Haloperidol; Male; Norepinephrine; Phenothiazines; Rats; Tyramine

1977
Inhibition of turning behaviour by clozapine in mice with unilateral destruction of dopaminergic nerve terminals.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:6

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Clozapine; Corpus Striatum; Dibenzazepines; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Mice; Models, Biological; Motor Activity; Time Factors

1975
Effects of clozapine on the activity of central dopaminergic and noradrenergic neurons.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:1

    Topics: Amphetamine; Animals; Brain; Clozapine; Dibenzazepines; Dopamine; Electric Stimulation; Locus Coeruleus; Male; Neurons; Norepinephrine; Rats; Substantia Nigra

1979
[Effect of clozapine on the behavioral and electrographic indices of the arrest function of the caudate nucleus in cats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1978, Volume: 85, Issue:5

    Topics: Amphetamine; Animals; Behavior, Animal; Cats; Caudate Nucleus; Clozapine; Dibenzazepines; Dose-Response Relationship, Drug; Electroencephalography; Female; Humans; Inhibition, Psychological; Male; Stereotyped Behavior

1978
Acidic dopamine metabolites in cortical areas of the rat brain: localization and effects of drug.
    Brain research, 1976, Aug-27, Volume: 113, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Cerebral Cortex; Clozapine; Corpus Striatum; Haloperidol; Homovanillic Acid; Male; Morphine; Olfactory Bulb; Oxotremorine; Phenylacetates; Probenecid; Rats; Sulpiride; Thioridazine

1976
Effect of neuroleptic drugs on mouse jumping induced by L-DOPA in amphetamine treated mice.
    Neuropharmacology, 1976, Volume: 15, Issue:11

    Topics: Amphetamine; Animals; Behavior; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Humans; Levodopa; Male; Mice; Pimozide; Promethazine; Psychotropic Drugs; Stereotyped Behavior; Thioridazine; Tranquilizing Agents

1976
Neuroleptic action of clozapine injected into various brain areas in rats.
    International pharmacopsychiatry, 1975, Volume: 10, Issue:2

    Topics: Amphetamine; Animals; Brain; Catalepsy; Cerebral Cortex; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzazepines; Hippocampus; Humans; Injections; Male; Rats; Stereotyped Behavior; Thalamus; Tranquilizing Agents

1975
Extrastriatal dopamine D2 receptors: distribution, pharmacological characterization and region-specific regulation by clozapine.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: Amphetamine; Animals; Autoradiography; Benzamides; Brain; Clozapine; Haloperidol; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone

1992
Changes of brain gangliosides in the frontal cortex of rats chronically treated with amphetamine, clozapine, haloperidol and ethanol.
    Biomedica biochimica acta, 1991, Volume: 50, Issue:7

    Topics: Amphetamine; Animals; Cerebral Cortex; Chromatography, Thin Layer; Clozapine; Ethanol; Gangliosides; Haloperidol; Male; Rats; Rats, Inbred Strains

1991
Amphetamine stimulation of glutaminase is blocked by neuroleptics.
    Life sciences, 1985, Mar-25, Volume: 36, Issue:12

    Topics: Amphetamine; Animals; Antipsychotic Agents; Brain; Butaclamol; Chlorpromazine; Clozapine; Enzyme Activation; Glutaminase; Haloperidol; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Stereoisomerism

1985
Antagonism of N-methyl-D-aspartate-induced transmitter release in the rat striatum by phencyclidine-like drugs and its relationship to turning behavior.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aspartic Acid; Benzomorphans; Chlorpromazine; Clozapine; Corpus Striatum; Cyclazocine; Dioxolanes; Dopamine; Haloperidol; Ketamine; Male; Mathematics; Motor Activity; N-Methylaspartate; Phencyclidine; Posture; Rats; Rats, Inbred Strains; Substantia Nigra

1985
Presynaptic dopamine autoreceptors control tyrosine hydroxylase activation in depolarized striatal dopaminergic terminals.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: Amphetamine; Animals; Bucladesine; Cerebral Cortex; Clozapine; Corpus Striatum; Dopamine; Enzyme Activation; Haloperidol; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Sulpiride; Synapses; Synaptosomes; Tyrosine 3-Monooxygenase; Veratridine

1986
Locus coeruleus norepinephrine-containing neurons: effects produced by acute and subchronic treatment with antipsychotic drugs and amphetamine.
    Brain research, 1986, Jan-01, Volume: 362, Issue:1

    Topics: Action Potentials; Amphetamine; Animals; Antipsychotic Agents; Clozapine; Dibenzazepines; Electric Stimulation; Haloperidol; Locus Coeruleus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Time Factors

1986
Antagonism of AP-5- and amphetamine-induced behaviour by timelotem as compared with clozapine and haloperidol.
    Life sciences, 1987, Oct-19, Volume: 41, Issue:16

    Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Behavior, Animal; Benzodiazepines; Clozapine; Dibenzazepines; Haloperidol; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereotyped Behavior; Valine

1987
Effects of acute and chronic clozapine and haloperidol on in vitro release of acetylcholine and dopamine from striatum and nucleus accumbens.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:2

    Topics: Acetylcholine; Amphetamine; Animals; Clozapine; Corpus Striatum; Dibenzazepines; Dopamine; Electric Stimulation; Haloperidol; In Vitro Techniques; Male; Nalidixic Acid; Naphthyridines; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Tetrahydronaphthalenes

1989
Inhibition of the electrically evoked release of [3H]acetylcholine in rat striatal slices: an experimental model for drugs that enhance dopaminergic neurotransmission.
    Journal of neurochemistry, 1985, Volume: 44, Issue:2

    Topics: Acetylcholine; Amphetamine; Animals; Chlorpromazine; Clozapine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Haloperidol; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Synaptic Transmission

1985
Electrophysiological evaluation of a partial agonist of dopamine receptors.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Clozapine; Dose-Response Relationship, Drug; Electric Stimulation; Ergolines; Haloperidol; Lisuride; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra

1987
Effects of drugs on schedule-controlled running of mice in a circular runway.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A

    Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Clozapine; Female; Food Deprivation; Imipramine; Mice; Morphine; Motor Activity; Pentobarbital; Reinforcement Schedule

1985
Behavioral, anti-dopaminergic, and prohypnotic effects of neuroleptics during and after prolonged treatment.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Clozapine; Dopamine; Dopamine Antagonists; Drug Tolerance; Female; Haloperidol; Hypnotics and Sedatives; Male; Mice; Motor Activity; Oxazoles; Piperazines; Receptors, Dopamine; Time Factors

1980
[Synthesis and neurologic action of new 11-substituted 5H-dibenzo[b,e][1,4]diazepines].
    Die Pharmazie, 1984, Volume: 39, Issue:12

    Topics: Aggression; Amphetamine; Analgesics; Animals; Brain Chemistry; Chemical Phenomena; Chemistry; Clozapine; Dibenzazepines; Hexobarbital; Homovanillic Acid; Humans; Lethal Dose 50; Mice; Motor Activity; Physostigmine; Psychotropic Drugs; Rats; Sleep

1984
Effects of catecholamine agonist and antagonist drugs on acute stomach ulceration induced by medial hypothalamic lesions in rats.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:5

    Topics: Amphetamine; Animals; Catecholamines; Chlorpromazine; Clozapine; Desipramine; Haloperidol; Hypothalamus, Middle; Isoproterenol; Male; Pargyline; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Stomach Ulcer

1983
Possible dopaminergic involvement in biting compulsion induced by large doses of clonidine.
    Pharmacological research communications, 1983, Volume: 15, Issue:6

    Topics: Aggression; Amphetamine; Animals; Clonidine; Clozapine; Dopamine; Drug Interactions; Female; Haloperidol; Humans; Male; Mice; Phenoxybenzamine; Scopolamine

1983
Differential sensitivity to amphetamine following long-term treatment with clozapine or haloperidol.
    Psychopharmacology, 1982, Volume: 77, Issue:4

    Topics: Amphetamine; Animals; Behavior, Animal; Clozapine; Dibenzazepines; Drug Tolerance; Haloperidol; Humans; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior

1982
[Possible discrepancy between behavioral adequacy and motor automatisms in cats with phenamine-induced stereotypy].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:8

    Topics: Amphetamine; Animals; Cats; Clozapine; Dibenzazepines; Female; Haloperidol; Humans; Male; Metoclopramide; Stereotyped Behavior

1981
Catalepsy as a rodent model for detecting antipsychotic drugs with extrapyramidal side effect liability.
    Psychopharmacology, 1995, Volume: 120, Issue:2

    Topics: Amphetamine; Animals; Antipsychotic Agents; Catalepsy; Clozapine; Disease Models, Animal; Extrapyramidal Tracts; Locomotion; Male; Rats; Rats, Sprague-Dawley; Time Factors

1995
Blockade of phencyclidine-induced hyperlocomotion by clozapine and MDL 100,907 in rats reflects antagonism of 5-HT2A receptors.
    European journal of pharmacology, 1995, Jul-04, Volume: 280, Issue:2

    Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Excitatory Amino Acid Antagonists; Fluorobenzenes; Male; Motor Activity; Phencyclidine; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists

1995
Atypical antipsychotics, clozapine and sulpiride do not antagonise amphetamine-induced stereotyped locomotion.
    Psychopharmacology, 1994, Volume: 114, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Clozapine; Haloperidol; Male; Motor Activity; Rats; Rats, Wistar; Stereotyped Behavior; Sulpiride

1994
Repeated treatment with ascorbate or haloperidol, but not clozapine, elevates extracellular ascorbate in the neostriatum of freely moving rats.
    Psychopharmacology, 1994, Volume: 116, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Ascorbic Acid; Clozapine; Extracellular Space; Haloperidol; Male; Microelectrodes; Motor Activity; Neostriatum; Nucleus Accumbens; Rats; Rats, Sprague-Dawley

1994
Seroquel: electrophysiological profile of a potential atypical antipsychotic.
    Psychopharmacology, 1993, Volume: 112, Issue:2-3

    Topics: Action Potentials; Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Brain; Clozapine; Dibenzothiazepines; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; Haloperidol; Male; Microelectrodes; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Substantia Nigra

1993
The effects of haloperidol and clozapine on PCP- and amphetamine-induced suppression of social behavior in the rat.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Aggression; Amphetamine; Animals; Clozapine; Haloperidol; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Social Behavior

1994
3-Benzisothiazolylpiperazine derivatives as potential atypical antipsychotic agents.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Brain; Catalepsy; Clozapine; Dopamine; Drug Design; Humans; Molecular Structure; Phosphatidylinositols; Piperazines; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Serotonin Antagonists; Thiazoles

1996
Amygdaloid neurons respond to clozapine rather than haloperidol in behaving rats pretreated with intra-amygdaloid amphetamine.
    Brain research, 1996, Mar-04, Volume: 711, Issue:1-2

    Topics: Amphetamine; Amygdala; Animals; Behavior, Animal; Clozapine; Haloperidol; Locomotion; Male; Rats; Rats, Sprague-Dawley

1996
Dopamine inhibits mammalian photoreceptor Na+,K+-ATPase activity via a selective effect on the alpha3 isozyme.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-23, Volume: 93, Issue:15

    Topics: Aminobutyrates; Amphetamine; Animals; Benzazepines; Clozapine; Darkness; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Agonists; Female; In Vitro Techniques; Isoenzymes; Kynurenic Acid; Light; Ouabain; Oxygen Consumption; Photoreceptor Cells; Rats; Retina; Retinal Rod Photoreceptor Cells; Rod Cell Outer Segment; Sodium-Potassium-Exchanging ATPase

1996
Preclinical neurochemical and electrophysiological profile of 1192U90, a potential antipsychotic.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1996, Volume: 15, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Biogenic Amines; Brain; Clozapine; Male; Neurons; Piperazines; Radioligand Assay; Rats; Thiazoles

1996
Olanzapine, a novel atypical antipsychotic, reverses d-amphetamine-induced inhibition of midbrain dopamine cells.
    Psychopharmacology, 1996, Volume: 124, Issue:1-2

    Topics: Amphetamine; Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dopamine Agents; Electrophysiology; Male; Mesencephalon; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley

1996
Inhibitory effects on the discriminative stimulus properties of D-amphetamine by classical and newer antipsychotics do not correlate with antipsychotic activity. Relation to effects on the reward system?
    Psychopharmacology, 1996, Volume: 124, Issue:1-2

    Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Clozapine; Discrimination Learning; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Wistar; Reward

1996
The effects of kainic acid lesions on locomotor responses to haloperidol and clozapine.
    Psychopharmacology, 1998, Volume: 135, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Clozapine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Haloperidol; Kainic Acid; Male; Motor Activity; Rats; Rats, Sprague-Dawley

1998
Clozapine and haloperidol block the induction of behavioral sensitization to amphetamine and associated genomic responses in rats.
    Brain research. Molecular brain research, 1998, Oct-30, Volume: 61, Issue:1-2

    Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Gene Expression Regulation; Genes, fos; Haloperidol; In Situ Hybridization; Injections, Subcutaneous; Male; Motor Activity; Neurotensin; Nucleus Accumbens; Peptide Fragments; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; RNA, Messenger

1998
Voluntary consumption of amphetamine, cocaine, ethanol and morphine by rats as influenced by a preceding period of forced drug intake and clozapine.
    Pharmacology, 1999, Volume: 58, Issue:6

    Topics: Administration, Oral; Amphetamine; Animals; Central Nervous System Depressants; Clozapine; Cocaine; Dopamine Agents; Ethanol; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders

1999
New and old antipsychotics versus clozapine in a monkey model: adverse effects and antiamphetamine effects.
    Psychopharmacology, 1999, Volume: 144, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Cebus; Clozapine; Dextroamphetamine; Disease Models, Animal; Dopamine Agents; Dystonia; Female; Male; Motor Activity; Movement Disorders

1999
S18327 (1-[2-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)piperid-1-yl]ethyl]3-phenyl imidazolin-2-one), a novel, potential antipsychotic displaying marked antagonist properties at alpha(1)- and alpha(2)-adrenergic receptors: II. Functional profile and a multipara
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Antagonists; Aggression; Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Clozapine; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Extrapyramidal Tracts; Haloperidol; Imidazoles; Isoxazoles; Male; Mice; Pain Measurement; Protein Binding; Rats; Rats, Wistar; Receptors, Histamine; Receptors, Muscarinic

2000
Atypical antipsychotic effects of quetiapine fumarate in animal models.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Disease Models, Animal; Female; Haloperidol; Immobilization; Male; Mice; Phencyclidine; Rats; Rats, Wistar; Schizophrenia; Schizophrenia, Paranoid

2000
Clozapine enhances breakpoint in common marmosets responding on a progressive ratio schedule.
    Psychopharmacology, 2001, Volume: 155, Issue:2

    Topics: Amphetamine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Callithrix; Central Nervous System Stimulants; Clozapine; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Eating; Female; Injections, Intramuscular; Male; Reinforcement Schedule

2001
Effects of JL13, a pyridobenzoxazepine with potential atypical antipsychotic activity, in animal models for schizophrenia.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Benzodiazepinones; Central Nervous System Stimulants; Clozapine; Disease Models, Animal; Drug Evaluation, Preclinical; Haloperidol; Locomotion; Male; Pyridines; Rats; Rats, Wistar; Reflex, Startle; Schizophrenia

2001
Clozapine and haloperidol reinstate latent inhibition following its disruption during amphetamine withdrawal.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:6

    Topics: Amphetamine; Animals; Antipsychotic Agents; Avoidance Learning; Central Nervous System Stimulants; Clozapine; Haloperidol; Inhibition, Psychological; Male; Rats; Rats, Wistar; Substance Withdrawal Syndrome

2002
Differential activation of orexin neurons by antipsychotic drugs associated with weight gain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Aug-01, Volume: 22, Issue:15

    Topics: Amphetamine; Animals; Antipsychotic Agents; Body Weight; Carrier Proteins; Cell Count; Central Nervous System Stimulants; Clozapine; Dopamine Antagonists; Fornix, Brain; Haloperidol; Hypothalamic Area, Lateral; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Neurons; Neuropeptides; Orexins; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Weight Gain

2002
Indoline and piperazine containing derivatives as a novel class of mixed D(2)/D(4) receptor antagonists. Part 2: asymmetric synthesis and biological evaluation.
    Bioorganic & medicinal chemistry letters, 2002, Nov-04, Volume: 12, Issue:21

    Topics: Amphetamine; Animals; Antipsychotic Agents; Binding, Competitive; Catalepsy; Central Nervous System Stimulants; Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; Half-Life; Haloperidol; Humans; In Vitro Techniques; Indicators and Reagents; Indoles; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D4; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship

2002
Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice.
    Molecular psychiatry, 2002, Volume: 7, Issue:10

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Clozapine; Dopamine Agonists; Dose-Response Relationship, Drug; Hallucinogens; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Parkinsonian Disorders; Protein Isoforms; Raclopride; Receptors, Dopamine D2

2002
Effects of haloperidol and clozapine on neuropeptide Y-like immunoreactivity in the nucleus accumbens and striatum of rats pretreated with psychostimulants.
    Neuropeptides, 2003, Volume: 37, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Hallucinogens; Haloperidol; Immunohistochemistry; Male; Motor Activity; Neostriatum; Neuropeptide Y; Nucleus Accumbens; Phencyclidine; Rats; Rats, Wistar; Stereotyped Behavior

2003
Latent inhibition in 35-day-old rats is not an "adult" latent inhibition: implications for neurodevelopmental models of schizophrenia.
    Psychopharmacology, 2003, Volume: 169, Issue:3-4

    Topics: Aging; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Conditioning, Classical; Disease Models, Animal; Drinking Behavior; Fluorobenzenes; Male; Models, Neurological; Movement; Neural Inhibition; Piperidines; Rats; Rats, Wistar; Schizophrenia; Time Factors

2003
Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:10

    Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Clozapine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Interactions; Female; GABA Antagonists; Haloperidol; Hippocampus; In Vitro Techniques; Inhibition, Psychological; Interferon Inducers; Male; Motor Activity; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Schizophrenia

2003
Haloperidol and clozapine antagonise amphetamine-induced disruption of latent inhibition of conditioned taste aversion.
    Psychopharmacology, 2003, Volume: 170, Issue:3

    Topics: Adrenergic Agents; Amphetamine; Animals; Antipsychotic Agents; Clozapine; Haloperidol; Male; Rats; Rats, Wistar; Reaction Time; Taste

2003
Clozapine treatment attenuated somatic and affective signs of nicotine and amphetamine withdrawal in subsets of rats exhibiting hyposensitivity to the initial effects of clozapine.
    Biological psychiatry, 2003, Dec-01, Volume: 54, Issue:11

    Topics: Affective Symptoms; Amphetamine; Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Male; Nicotine; Rats; Rats, Wistar; Reward; Substance Withdrawal Syndrome

2003
Effects of acute and chronic clozapine on D-amphetamine-induced disruption of auditory gating in the rat.
    Psychopharmacology, 2004, Volume: 174, Issue:2

    Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Dose-Response Relationship, Drug; Evoked Potentials, Auditory; Male; Rats; Rats, Sprague-Dawley

2004
A putative animal model of the "prodromal" state of schizophrenia.
    Biological psychiatry, 2005, Mar-15, Volume: 57, Issue:6

    Topics: Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Benzazepines; Central Nervous System Stimulants; Clozapine; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Haloperidol; Inhibition, Psychological; Male; Motor Activity; Neural Inhibition; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex, Startle; Schizophrenia; Substance Withdrawal Syndrome; Time Factors

2005
Neurotensin-deficient mice have deficits in prepulse inhibition: restoration by clozapine but not haloperidol, olanzapine, or quetiapine.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Benzodiazepines; Body Weight; Clozapine; Dibenzothiazepines; Female; Haloperidol; Male; Mice; Mice, Inbred C57BL; Neurotensin; Olanzapine; Quetiapine Fumarate; Reflex; Reflex, Startle

2005
The effects of antipsychotics on beta-catenin, glycogen synthase kinase-3 and dishevelled in the ventral midbrain of rats.
    Journal of neurochemistry, 2005, Volume: 95, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Amphetamine; Animals; Antipsychotic Agents; Benzazepines; beta Catenin; Blotting, Western; Central Nervous System Stimulants; Clozapine; Cytoskeletal Proteins; Dishevelled Proteins; Dopamine Agonists; Female; Glycogen Synthase Kinase 3; Haloperidol; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Male; Mesencephalon; Phosphoproteins; Quinpirole; Rats; Rats, Sprague-Dawley; Risperidone; Signal Transduction; Trans-Activators; Wnt Proteins; Wnt1 Protein

2005
The role of 5-HT(2A) receptor antagonism in amphetamine-induced inhibition of A10 dopamine neurons in vitro.
    European journal of pharmacology, 2005, Sep-27, Volume: 520, Issue:1-3

    Topics: Action Potentials; Amphetamine; Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluorobenzenes; In Vitro Techniques; Male; Mesencephalon; Neural Inhibition; Neurons; Olanzapine; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin 5-HT2 Receptor Antagonists; Sulpiride

2005
Neonatal neurosteroid administration results in development-specific alterations in prepulse inhibition and locomotor activity: neurosteroids alter prepulse inhibition and locomotor activity.
    Psychopharmacology, 2006, Volume: 186, Issue:3

    Topics: Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Clozapine; Female; GABA Antagonists; Male; Motor Activity; Pregnanolone; Rats; Rats, Sprague-Dawley; Reflex, Startle

2006
Antipsychotic pathway genes with expression altered in opposite direction by antipsychotics and amphetamine.
    Synapse (New York, N.Y.), 2006, Volume: 60, Issue:2

    Topics: Amphetamine; Animals; Antipsychotic Agents; Brain; Brain Chemistry; Chromosome Mapping; Clozapine; Dopamine Agents; Down-Regulation; Gene Expression Regulation; Haloperidol; Male; Molecular Sequence Data; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Schizophrenia; Up-Regulation

2006
Effects of tryptophan deficiency on prepulse inhibition of the acoustic startle in rats.
    Psychopharmacology, 2008, Volume: 198, Issue:2

    Topics: Acoustic Stimulation; Amino Acids; Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Data Interpretation, Statistical; Diet; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Eating; Flour; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle; Tryptophan; Zea mays

2008
A comparison of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in DBA/2 and C57BL/6 inbred mice.
    Behavioural pharmacology, 2008, Volume: 19, Issue:5-6

    Topics: Amphetamine; Animals; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Discrimination Learning; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Olanzapine; Risperidone

2008
Amisulpride the 'atypical' atypical antipsychotic--comparison to haloperidol, risperidone and clozapine.
    Schizophrenia research, 2008, Volume: 105, Issue:1-3

    Topics: Amisulpride; Amphetamine; Animals; Antipsychotic Agents; Basal Ganglia; Behavior, Animal; Blood-Brain Barrier; Brain; Clozapine; Conditioning, Psychological; Haloperidol; Male; Models, Animal; Motor Activity; Phencyclidine; Prefrontal Cortex; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Serotonin; Risperidone; Sulpiride

2008
Decreased M1 muscarinic receptor density in rat amphetamine model of schizophrenia is normalized by clozapine, but not haloperidol.
    Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:11

    Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; DNA Primers; Haloperidol; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schizophrenia; Schizophrenic Psychology

2008
Evaluating early preventive antipsychotic and antidepressant drug treatment in an infection-based neurodevelopmental mouse model of schizophrenia.
    Schizophrenia bulletin, 2010, Volume: 36, Issue:3

    Topics: Age Factors; Amphetamine; Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brain; Central Nervous System Stimulants; Clozapine; Disease Models, Animal; Female; Haloperidol; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neural Inhibition; Polynucleotides; Pregnancy; Prenatal Exposure Delayed Effects; Schizophrenia; Schizophrenic Psychology; Sensory Gating

2010
Repeated antipsychotic treatment progressively potentiates inhibition on phencyclidine-induced hyperlocomotion, but attenuates inhibition on amphetamine-induced hyperlocomotion: relevance to animal models of antipsychotic drugs.
    European journal of pharmacology, 2009, Jan-14, Volume: 602, Issue:2-3

    Topics: Amphetamine; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Clozapine; Disease Models, Animal; Haloperidol; Hyperkinesis; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Time Factors

2009
Are DBA/2 mice associated with schizophrenia-like endophenotypes? A behavioural contrast with C57BL/6 mice.
    Psychopharmacology, 2009, Volume: 206, Issue:4

    Topics: Amphetamine; Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Phencyclidine; Phenotype; Reflex, Startle; Schizophrenia; Species Specificity

2009
Glutaminase-deficient mice display hippocampal hypoactivity, insensitivity to pro-psychotic drugs and potentiated latent inhibition: relevance to schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:10

    Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exploratory Behavior; Freezing Reaction, Cataleptic; Glutamic Acid; Glutaminase; Hippocampus; Image Processing, Computer-Assisted; Inhibition, Psychological; Ketamine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Maze Learning; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Motor Activity; Oxygen; Protons; Reflex, Startle; Synaptic Transmission

2009
Disruption of mesolimbic regulation of prefrontal cholinergic transmission in an animal model of schizophrenia and normalization by chronic clozapine treatment.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:13

    Topics: Acetylcholine; Aging; Amphetamine; Animals; Animals, Newborn; Clozapine; Disease Models, Animal; Hippocampus; Ibotenic Acid; Male; Microinjections; N-Methylaspartate; Neural Pathways; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Schizophrenia; Time Factors

2009
Clozapine administration in adolescence prevents postpubertal emergence of brain structural pathology in an animal model of schizophrenia.
    Biological psychiatry, 2009, Dec-01, Volume: 66, Issue:11

    Topics: Abnormalities, Drug-Induced; Age Factors; Amphetamine; Animals; Antipsychotic Agents; Attention; Brain Diseases; Cerebral Ventricles; Clozapine; Disease Models, Animal; Hippocampus; Inhibition, Psychological; Male; Motor Activity; Poly I-C; Rats; Rats, Wistar; Schizophrenia

2009
The glycine transporter-1 inhibitor SSR103800 displays a selective and specific antipsychotic-like profile in normal and transgenic mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:2

    Topics: Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Aripiprazole; Catalepsy; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Plasma Membrane Transport Proteins; Glycine Plasma Membrane Transport Proteins; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Piperazines; Quinolones; Receptors, N-Methyl-D-Aspartate

2010
Chronic NT69L potently prevents drug-induced disruption of prepulse inhibition without causing tolerance.
    Behavioural brain research, 2010, Feb-11, Volume: 207, Issue:1

    Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Antipsychotic Agents; Clozapine; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Haloperidol; Neurotensin; Peptide Fragments; Rats; Sensory Gating

2010
A new model of the disrupted latent inhibition in C57BL/6J mice after bupropion treatment.
    Psychopharmacology, 2010, Volume: 208, Issue:3

    Topics: Amphetamine; Animals; Bupropion; Clozapine; Conditioning, Psychological; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Drug Interactions; Haloperidol; Inhibition, Psychological; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Phosphodiesterase 4 Inhibitors; Piperazines; Rolipram; Schizophrenic Psychology

2010
Contrasting effects of increased and decreased dopamine transmission on latent inhibition in ovariectomized rats and their modulation by 17beta-estradiol: an animal model of menopausal psychosis?
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:7

    Topics: Amphetamine; Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogens; Female; Haloperidol; Inhibition, Psychological; Ovariectomy; Psychotic Disorders; Rats; Rats, Wistar; Statistics, Nonparametric; Water Deprivation

2010
Hyperactivity of the hypothalamus-pituitary-adrenal axis in lipopolysaccharide-induced neurodevelopmental model of schizophrenia in rats: effects of antipsychotic drugs.
    European journal of pharmacology, 2011, Jan-15, Volume: 650, Issue:2-3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Corticosterone; Female; Frontal Lobe; Hippocampus; Hypothalamo-Hypophyseal System; Lipopolysaccharides; Male; Maternal Exposure; Maternal-Fetal Exchange; Motor Activity; Pituitary-Adrenal System; Pregnancy; Rats; Rats, Wistar; Receptors, Glucocorticoid; Reflex, Startle; Schizophrenia; Tacrolimus Binding Proteins

2011
Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization.
    Nature neuroscience, 2011, Volume: 14, Issue:1

    Topics: Amphetamine; Animals; Cell Line, Transformed; Clozapine; Corpus Striatum; Dopamine; Genetic Vectors; Herpes Simplex; Humans; Male; Membrane Potentials; Motor Activity; Neural Inhibition; Neural Pathways; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M4; Reward; Ventral Tegmental Area

2011
Spontaneously Hypertensive Rats (SHR) present deficits in prepulse inhibition of startle specifically reverted by clozapine.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Aug-15, Volume: 35, Issue:7

    Topics: Acoustic Stimulation; Amphetamine; Animals; Antimanic Agents; Antipsychotic Agents; Carbamazepine; Clozapine; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Male; Metoclopramide; Rats; Rats, Inbred SHR; Rats, Wistar; Reflex, Startle; Schizophrenia; Sensory Gating

2011
Clozapine, but not olanzapine, disrupts conditioned avoidance response in rats by antagonizing 5-HT2A/2C receptors.
    Journal of neural transmission (Vienna, Austria : 1996), 2012, Volume: 119, Issue:4

    Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Avoidance Learning; Benzodiazepines; Clozapine; Conditioning, Classical; Dose-Response Relationship, Drug; Inhibition, Psychological; Male; Olanzapine; Phencyclidine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Time Factors

2012
A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Animals, Newborn; Clozapine; Cocaine; Corpus Striatum; Cyclic AMP; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Green Fluorescent Proteins; GTP-Binding Protein alpha Subunits, Gs; Locomotion; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Phosphorylation; Receptor, Adenosine A2A; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, G-Protein-Coupled; Receptors, Muscarinic; Red Fluorescent Protein

2013
Clozapine pre-treatment has a protracted hypolocomotor effect on the induction and expression of amphetamine sensitization.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Dec-02, Volume: 47

    Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Drug Administration Schedule; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Time Factors

2013
Behavioral effects of clozapine, pimavanserin, and quetiapine in rodent models of Parkinson's disease and Parkinson's disease psychosis: evaluation of therapeutic ratios.
    Behavioural pharmacology, 2013, Volume: 24, Issue:7

    Topics: Amphetamine; Animals; Antiparkinson Agents; Antipsychotic Agents; Apomorphine; Clozapine; Dopamine; Dose-Response Relationship, Drug; Male; Parkinsonian Disorders; Piperidines; Psychotic Disorders; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Urea

2013
Locomotor hyperactivity in 14-3-3ζ KO mice is associated with dopamine transporter dysfunction.
    Translational psychiatry, 2013, Dec-03, Volume: 3

    Topics: 14-3-3 Proteins; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Mice; Mice, Knockout; Motor Activity; Neostriatum; Schizophrenia; Signal Transduction; Synaptic Transmission

2013
Ventral Tegmental Area Dopamine Cell Activation during Male Rat Sexual Behavior Regulates Neuroplasticity and d-Amphetamine Cross-Sensitization following Sex Abstinence.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 09-21, Volume: 36, Issue:38

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Clozapine; Conditioning, Operant; Designer Drugs; Dopaminergic Neurons; Female; Gene Expression Regulation; Luminescent Proteins; Male; Neuronal Plasticity; Proto-Oncogene Proteins c-fos; Rats; Receptors, G-Protein-Coupled; Red Fluorescent Protein; Reward; Sexual Behavior, Animal; Transduction, Genetic; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2016
Cortical high gamma network oscillations and connectivity: a translational index for antipsychotics to normalize aberrant neurophysiological activity.
    Translational psychiatry, 2017, 12-18, Volume: 7, Issue:12

    Topics: Amphetamine; Animals; Antipsychotic Agents; Benzodiazepines; Brain Waves; Central Nervous System Stimulants; Cerebral Cortex; Clozapine; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Nerve Net; Olanzapine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Risperidone

2017
Cannabidiol prevents disruptions in sensorimotor gating induced by psychotomimetic drugs that last for 24-h with probable involvement of epigenetic changes in the ventral striatum.
    Progress in neuro-psychopharmacology & biological psychiatry, 2021, 12-20, Volume: 111

    Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Cannabidiol; Clozapine; Dizocilpine Maleate; DNA Methylation; Epigenesis, Genetic; Hallucinogens; Male; Mice; Neuroprotective Agents; Prefrontal Cortex; Prepulse Inhibition; Reflex, Startle; Schizophrenia; Sensory Gating; Time Factors; Ventral Striatum

2021
Association of clozapine treatment and rate of methamphetamine or amphetamine relapses and abstinence among individuals with concurrent schizophrenia spectrum and amphetamine use disorder: A retrospective cohort study.
    Journal of psychopharmacology (Oxford, England), 2023, Volume: 37, Issue:10

    Topics: Amphetamine; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Female; Humans; Male; Methamphetamine; Recurrence; Retrospective Studies; Schizophrenia; Substance-Related Disorders

2023
Repeated chemogenetic activation of dopaminergic neurons induces reversible changes in baseline and amphetamine-induced behaviors.
    Psychopharmacology, 2023, Volume: 240, Issue:12

    Topics: Amphetamine; Animals; Clozapine; Dopaminergic Neurons; Mice

2023