ampelopsin has been researched along with 3-hydroxyflavone in 258 studies
| Studies (ampelopsin) | Trials (ampelopsin) | Recent Studies (post-2010) (ampelopsin) | Studies (3-hydroxyflavone) | Trials (3-hydroxyflavone) | Recent Studies (post-2010) (3-hydroxyflavone) |
|---|---|---|---|---|---|
| 377 | 2 | 343 | 3,657 | 84 | 2,242 |
| Protein | Taxonomy | ampelopsin (IC50) | 3-hydroxyflavone (IC50) |
|---|---|---|---|
| Pyruvate kinase PKM | Homo sapiens (human) | 1.75 | |
| Cytochrome P450 1B1 | Homo sapiens (human) | 0.09 | |
| Aurora kinase B | Homo sapiens (human) | 4.29 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (3.10) | 29.6817 |
| 2010's | 146 (56.59) | 24.3611 |
| 2020's | 104 (40.31) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, W; Du, Q; Ito, Y; Xia, M | 1 |
| He, GX; Pei, G; Zhou, TD; Zhou, XX | 1 |
| Li, R; Wang, Y; Zhou, L | 1 |
| Ning, ZX; Wu, H; Yang, SZ; Zhang, YS | 1 |
| Du, FL; He, GX; Pei, G; Yang, WL; Zhu, YH | 1 |
| Qiao, L; Que, S; Wang, B; Yang, X; Zhang, Y; Zhao, Y | 1 |
| Guo, DA; Li, LY; Wang, B; Zhang, QY; Zhang, YS; Zhao, YY | 1 |
| Liang, GZ; Liu, BG; Ning, ZX; Yang, JG | 1 |
| Bhattacharyya, MK; Brar, HK; Grosic, S; Palmer, RG; Xu, M | 1 |
| Gao, Q; Ou, M; Yang, X | 1 |
| Chen, F; Fu, C; Hua, X; Li, H; Lv, X; Qiu, J; Zhao, D; Zhao, Q | 1 |
| Luo, P; Xu, Y; Ye, B; Zhang, S; Zou, L | 1 |
| Gonzalez, C; Liang, J; Lindemeyer, AK; Olsen, RW; Shao, XM; Shen, Y; Spigelman, I | 1 |
| Cao, H; Chen, T; Jiang, G; Lu, T; Lu, Y; Zhao, Y; Zhu, L; Zhu, S | 1 |
| Chen, T; Ge, C; Jiang, G; Shang, Y; Zhu, S | 1 |
| Chen, LF; Wang, XH; Wang, XQ; Yang, XM | 1 |
| Cai, ZZ; Ding, Y; Jin, MY; Tao, JS; Zhang, T | 1 |
| Chen, L; Ning, Z; Wang, C; Wei, Q; Yuan, E | 1 |
| Hu, M; Huang, H; Li, M; Li, P; Zhao, R | 1 |
| Bao, S; Li, M; Liu, B; Liu, J; Wang, C; Wu, S; Zhang, Q; Zhou, W; Zhu, R | 1 |
| Fang, T; Feng, D; Guo, S; Li, M; Liu, B; Liu, J; Xia, J; Zhang, Q; Zhang, X; Zhu, R | 1 |
| Chang, H; Chen, K; Liu, P; Mi, M; Zhu, J; Zou, D | 1 |
| Kwon, B; Liang, J; Ly, E; Nguyen, A; Olsen, RW; Scott, MB; Shao, XM; Shen, Y; Spigelman, I; Tan, K; Wong, S | 1 |
| Jia, YH; Zhu, X | 1 |
| Cao, Y; Chen, N; Chen, X; Li, M; Liu, B; Liu, J; Lu, C; Xia, J; Zhang, C; Zhang, Q; Zhu, R | 1 |
| Liang, J; Lindemeyer, AK; López-Valdés, HE; Martínez-Coria, H; Olsen, RW; Shao, XM; Shen, Y | 1 |
| Chen, H; Li, M; Liu, B; Liu, J; Zeng, G; Zhang, Q; Zhu, R | 1 |
| Liao, W; Ma, L; Ning, Z; Ren, J; Wei, Q; Yang, J; Yin, X; Yuan, E | 1 |
| Jia, Q; Kang, T; Lu, J; Shen, J; Song, G; Tang, Q; Wang, J; Wang, Y; Wu, MS; Wu, Y; Xie, XB; Yin, JQ; Zhao, Z; Zou, C | 1 |
| Li, MY; Li, R; Liu, B; Liu, J; Liu, ZK; Miao, HL; Qiu, ZD; Shu, Y; Wang, DJ; Zeng, GF; Zhang, QY; Zhu, RZ | 1 |
| Gao, H; Liang, X; Qiu, JH; Wu, YP; Zhong, K | 1 |
| Chang, L; Dai, J; Fu, Y; He, Q; Luo, P; Shao, J; Wang, J; Weng, Q; Yang, B; Yang, X; Zhu, H | 1 |
| Bao, S; Chen, N; Chen, X; Chen, Y; Li, M; Liu, B; Liu, J; Xu, F; Zhang, Q; Zhou, W; Zhu, R | 1 |
| Liang, J; Lin, B; Liu, B; Liu, J; Tan, X; Wu, S; Zhang, Q; Zhu, R | 1 |
| Duncan, SE; Eigel, WN; O'Keefe, SF; Wang, H; Ye, L | 1 |
| Hu, K; Jiang, B; Le, L; Pan, H; Xiao, P; Xu, L | 1 |
| Liao, SF; Wang, HT; Yan, FX; Zeng, ZW; Zheng, WH; Zheng, YX | 1 |
| Chen, Y; Meng, G; Yang, S; Yao, W; Zhang, W; Zhu, H | 1 |
| Anzenbacherova, E; Brabencova, E; Brotanek, J; Fousova, P; Frei, E; Hodek, P; Hudecek, J; Moserova, M; Pavek, P; Stiborova, M | 1 |
| Hou, X; Li, W; Liu, B; Lou, W; Wan, D; Wu, H; Zhao, J | 1 |
| Chen, M; Hu, Q; Huang, J; Liang, X; Mi, M; Shi, L; Zhang, Q; Zhang, T; Zhou, Y; Zhu, J | 1 |
| Fang, J; Hou, X; Shi, C; Tong, Q; Wang, W; Xiong, W | 1 |
| Mi, M; Ran, L; Shi, L; Zeng, X; Zhang, Q; Zhang, T; Zhou, Y; Zhu, J | 1 |
| Jiang, L; Li, M; Liang, J; Liu, B; Liu, J; Lu, C; Ma, S; Ren, H; Zhang, Q; Zhu, R | 1 |
| Chow, LM; Duan, LX; Hu, X; Jiang, T; Li, XM; Liu, T; Liu, Z; Wan, SB; Wang, BC; Wong, IL; Yuan, J; Zhang, XY | 1 |
| Chen, TM; Dai, D; Hu, LP; Lan, Q; Liu, B; Liu, J; Xie, J; Zhang, QY; Zhang, WD; Zhu, RZ | 1 |
| Chen, S; Gao, Y; Liu, P; Mi, M; Qin, Y; Ran, L; Shu, F; Wan, J; Wang, X; Zhang, Q; Zhang, Y; Zhao, X; Zhu, J | 1 |
| Chen, K; Deng, H; Gao, Y; Huang, Y; Liu, P; Mi, M; Zhang, Q; Zhou, Q; Zhu, J; Zou, D | 1 |
| Fang, J; Hou, X; Liu, X; Shi, C; Tong, Q; Wang, W; Xie, X; Xiong, W | 1 |
| Chen, J; Fang, JG; Hou, XL; Liu, X; Shi, CY; Tong, Q; Wang, WQ; Xiong, W | 1 |
| Jiang, SP; Jiang, ZH; Leung, EL; Li, T; Liu, J; Liu, L; Liu, Y; Su, XH; Wang, TY; Wong, VK; Wong, YF; Yan, FG; Yao, XJ; Yi, XQ; Zhou, H | 1 |
| Fang, XD; Fu, LB; Ji, FJ; Jin, HY; Liu, XW; Tian, XF; Wu, YY | 1 |
| Chen, K; Gao, Y; Huang, Y; Liu, P; Mi, M; Zhang, Q; Zhou, Q; Zhu, J; Zou, D | 1 |
| Bostikova, Z; Hodek, P; Moserova, M; Pavek, P; Stiborova, M | 1 |
| Jiao, P; Liu, Q; Wang, JT; Zhou, Y | 1 |
| Chen, D; Huang, J; Li, X; Lin, J; Lin, Y; Liu, J; Wang, T | 1 |
| He, Z; Jin, F; Wang, Y; Zhang, L; Zhuo, C | 1 |
| Chen, Z; Han, T; Jin, J; Wang, J; Xie, C; Xu, X; Zhan, W; Zhang, C | 1 |
| Cao, T; Ren, ZX; Zhao, YF; Zhen, XC | 1 |
| Calvin Sun, C; Fang, J; Reddy Perumalla, S; Wang, C; Xiong, W | 1 |
| Chen, E; Gao, X; Pan, Z; Wang, S; Xue, D; Yin, H; Zhang, W; Zheng, Q | 1 |
| Bu, LL; Fan, TF; Li, YC; Ma, SR; Mao, L; Sun, ZJ; Wu, TF; Zhang, WF | 1 |
| Cai, J; Huang, L; Li, T; Liu, J; Liu, L; Pi, J; Su, X; Wang, R; Wong, I; Zeng, X; Zhou, H | 1 |
| Chen, S; Jia, Y; Lei, W; Li, K; Li, Y; Liu, B; Liu, Z; Ma, Y; Mu, S; OuYang, L; Wang, W; Wu, J; Zhan, M; Zhu, Y | 1 |
| Chang, JH; Chien, MH; Chow, JM; Chung, CL; Hung, WY; Kao, SJ; Lee, WJ | 1 |
| Pu, Q; Qin, M; Tian, M; Xie, G; Zhang, H | 1 |
| Chang, TM; Chen, CC; Huang, HC; Liao, CC; Lim, JM; Peng, CC; Siao, JH; Wei, CM; Wu, CS | 1 |
| Jin, X; Lee, JJ; Li, X; Lv, Y; Ma, J; Mi, C; Piao, LX; Tang, N; Wang, KS; Xu, GH | 1 |
| Bai, J; Gao, H; Huang, Y; Wu, Y; Zhong, K | 1 |
| Ai, Q; Feng, K; Li, Y; Liu, S; Liu, X | 1 |
| Han, WN; Li, BR; Tang, S; Wang, L; Xia, LQ | 1 |
| Chen, J; Chen, Y; Chi, X; Guo, D; Jiang, Y; Jiang, Z; Lin, J; Lv, L; Pi, H; Qin, W; Yang, H | 1 |
| Hu, K; Jiang, B; Le, L; Wan, W; Xiao, P; Xu, L; Zhai, W | 1 |
| Lang, H; Liu, L; Mi, M; Si, M; Wan, J; Zhou, Y; Zhu, J | 1 |
| Chen, J; E, Q; Feng, Y; Ji, Q; Li, Q; Liu, X; Sui, H; Sun, X; Wang, Z; Wu, L; Zhou, L | 1 |
| Fang, JG; Shi, CY; Wang, CG; Wang, MD; Wang, WQ; Xiang, D; Xiong, W | 1 |
| Bao, S; Guan, X; Hao, S; Huang, X; Lian, T; Liu, B; Tan, X; Zhang, J; Zhu, R | 1 |
| Cao, SL; Deng, X; Huang, ZX; Li, XH; Lou, WY; Xu, P; Zhou, J; Zong, MH | 1 |
| Chen, K; Gong, X; Gu, Y; Lang, H; Mi, M; Ran, L; Wang, X; Zhou, M; Zhou, Q; Zhu, J | 1 |
| Chen, S; Han, L; Liao, Q; Xu, Y; Yao, A; Zhang, H; Zhang, X; Zhang, Z; Zou, Z | 1 |
| Fang, S; Huang, S; Wang, C; Xu, B; Zhang, H; Zhang, Y | 1 |
| Dong, Y; Du, WF; Ge, WH; Gu, C; Kang, XJ; Li, B; Luo, YY; Pang, MX; Qiu, P; Zhu, T | 1 |
| Fan, M; Guo, T; Han, D; Lin, J; Luo, J; Tao, L; Wu, B; Yi, F; Yuan, M | 1 |
| Chan, HF; Chen, M; He, C; Lin, Z; Lu, H; Wang, S; Xu, Y | 1 |
| Chen, YM; Peng, Y; Sun, HY; Yue, JQ; Zhong, ZJ; Zhou, DZ | 1 |
| Chen, X; Liu, TT; Tang, K; Xu, XL; Zeng, Y; Zhang, W | 1 |
| Dong, W; Fan, L; Fang, J; Hou, X; Shi, C; Tong, Q; Wang, W; Xiong, W; Yang, G | 1 |
| Dalcin, AJF; Gomes, P; Gündel, SS; Ourique, AF; Raffin, RP; Roggia, I; Santos, CG; Santos, RCV | 1 |
| Dong, X; Lu, S; Luo, Y; Sun, G; Sun, X; Xu, L | 1 |
| Fan, M; Gong, D; Pan, J; Zhang, G | 1 |
| Huang, Y; Jian, W; Wang, G; Zhao, J | 1 |
| Cheng, K; Fan, D; Wang, M; Wang, X; Zhao, Y; Zhou, B | 1 |
| Duan, J; He, YF; He, YH; Li, MY; Liang, YR; Lu, CJ; Xiang, LJ; Yuan, WZ; Zhang, J | 1 |
| Cheng, W; Deng, CJ; Jin, LP; Peng, N; Shao, L; Wei, GZ; Wu, J; Zhou, MQ | 1 |
| Fan, KJ; Liu, Y; Tian, XD; Wang, B; Yang, B | 1 |
| Kirby, BP; Ren, Z; Waddington, JL; Yan, P; Yang, H; Zhao, Y; Zhen, X; Zhu, L | 1 |
| Chen, J; Huang, W; Huang, Z; Li, Q; Liu, S; Ye, Y | 1 |
| Li, Q; Wang, J; Wu, X; Xie, J; Xu, Y; Yu, J; Zeng, Z; Zhu, X | 1 |
| Lang, H; Liu, L; Mi, M; Zhou, M; Zhou, Y | 1 |
| Hu, Q; Mi, M; Yi, L; Zhang, T; Zhou, X | 1 |
| Fu, HL; He, MH; Liang, XX; Lin, JC; Shi, F; Shu, G; Yin, L; Yuan, ZX; Zhang, Q; Zhao, L | 1 |
| Bai, DD; Bai, JR; Gao, H; Huang, YN; Ran, Y; Wu, YP; Xiao, K; Zhong, K | 1 |
| Han, J; Hassan, YI; Lu, H; Lu, Z; Muhammad, U; Tayyaba, S; Wang, J; Zhu, X | 1 |
| Chen, MT; Kang, C; Liu, K; Mi, MT; Wang, B; Wang, XL; Zhang, QY; Zhang, Y; Zhou, M; Zhu, JD; Zhu, XH | 1 |
| Feng, S; He, J; Liao, D; Ling, H; Wu, D; Yang, J; Yang, S; Zhu, Z | 1 |
| Gao, J; Hao, Z; Liang, L; Lin, Q; Wang, F; Zhou, Q; Zhu, Y | 1 |
| Peng, Y; Tang, K; Wang, YQ; Wei, XY; Xu, XL; Zeng, Y; Zhao, ZY | 1 |
| Bi, H; Chu, J; Li, L; Ren, M; Wang, J; Wang, X | 1 |
| Chen, J; Fan, L; Fang, J; Shi, C; Tong, Q; Wang, W; Xiong, W; Zhao, X; Zhou, X | 1 |
| Bai, JR; Gao, H; Grosu, E; Huang, YN; Liu, LJ; Tang, MM; Wu, YP; Zhong, K | 1 |
| Chen, JF; Du, YH; Feng, J; He, GQ; Liu, Y; Liu, YJ; Wang, JX; Wang, KJ; Zhang, W; Zheng, M | 1 |
| Li, Y; Sun, C; Wen, J; Yang, X; Zeng, H; Zhou, C; Zou, H | 1 |
| Cui, HQ; Gao, Y; Huang, YZ; Liu, JQ; Peng, CY; Shu, JC; Zhang, R | 1 |
| Feng, SD; He, JQ; Ling, HY; Yang, JH; Yang, SS; Zhang, KF; Zhu, ZM | 1 |
| Fan, L; Fang, JG; Hou, XL; Shi, CY; Wang, WQ; Xiang, D; Xiong, W | 1 |
| Cheng, C; Feng, ZJ; Jiang, H; Liu, CM; Ma, JQ; Sun, JM; Yang, HX; Yang, W | 1 |
| Li, Y; Peng, J; Qiao, L; Tian, Y; Zhang, J; Zhang, L | 1 |
| Han, J; Meng, F; Qu, D; Wang, D; Xu, M; Zhang, X; Zheng, Q | 1 |
| Jia, R; Ma, J; Meng, W; Wang, N | 1 |
| Chen, A; Fang, H; Fang, J; Guo, F; Hou, X; Huang, S; Li, F; Li, X; Zhang, X | 1 |
| Chen, K; Huang, Y; Mi, M; Ren, Q; Yi, L; Zhang, Q; Zhu, J | 1 |
| Huo, X; Liu, K; Liu, W; Liu, Z; Ma, X; Meng, Q; Peng, J; Sun, H; Sun, P; Sun, Y; Wang, C; Yang, X | 1 |
| Chen, M; Huang, B; Li, Y; Shu, W; Yao, Y | 1 |
| Hu, X; Liu, X; Tao, NP; Teng, J; Wang, M; Zhao, Y | 1 |
| Bao, XF; Chen, Y; Liu, LL; Luo, HQ; Meng, GL; Sun, LL; Wang, HX; Wang, YQ; Xu, MT; Yu, J; Zhang, JY | 1 |
| Li, T; Liao, K; Liu, L; Liu, Z; Meng, X; Ren, R; Ting Kam, RK; Wang, J; Yan, F; Yang, F; Zeng, X; Zhou, H | 1 |
| Chang, YY; Hsieh, YH; Lin, HW; Lin, HY; Wang, K; Yang, SF; Yu, NY | 1 |
| Fan, P; Hu, J; Huang, C; Lin, D; Pan, X; Tian, N; Wang, J; Wang, K; Wang, X; Wu, Y; Xu, D; Zhang, X; Zhou, Y | 1 |
| Guo, J; Liu, LH; Qu, CH; Sun, P; Wang, CX; Wang, SH; Yin, JB | 1 |
| Bochi, GV; Dalcin, AJF; Gomes, P; Guarda, NS; Moresco, RN; Nascimento, K; Ourique, AF; Sagrillo, MR; Schuch, AP; Vizzotto, BS | 1 |
| Liang, J; Wang, F; Wu, J; Zhang, P; Zhang, X | 1 |
| Guo, L; Yan, X; Zhang, H | 1 |
| Cui, ZG; Feng, QW; Inadera, H; Jin, YJ; Li, ML; Sun, L; Zakki, SA; Zhou, DJ | 1 |
| Pang, Z; Ye, X; Zhu, N | 1 |
| Bi, X; Han, W; He, T; Jiang, W; Li, Y; Liu, C; Liu, Y; Xiao, T; Xiong, J; Xu, X; Yang, K; Yu, Y; Zhang, B; Zhang, J; Zhao, J | 1 |
| Li, H; Miu, J; Sun, X; Xiao, P; Xu, L; Yu, F | 1 |
| Bai, XJ; Gao, W; Li, ZF; Liu, QX; Liu, T; Liu, XH; Wang, YC; Xu, XE; Zheng, Q | 1 |
| Chen, B; Cui, W; Jia, L; Liu, F; Lu, F; Sang, J; Wang, Y; Wei, W; Zhao, W | 1 |
| Hui, SC; Kang, C; Lang, HD; Mi, MT; Wang, XL; Yi, L; Zhang, Y; Zhou, M; Zhu, XH | 1 |
| Dong, S; Hu, L; Ji, J; Wang, H | 1 |
| Huang, J; Ma, Y; Sun, R; Wang, D; Wang, Q; Xia, Q | 1 |
| Cai, H; Chen, L; Deng, Y; Fang, P; Guo, L; He, G; Li, H; Tan, S; Xiang, D; Yan, M; Zhang, B | 1 |
| Cao, H; Liao, R; Peng, L; Qiu, X; Tian, X; Wang, L; Yan, F; Yang, Q; Zhang, X | 1 |
| Li, Y; Qi, X; Sun, X; Wei, L; Xu, Y; Zhang, Y | 1 |
| Fan, L; Fang, J; Gong, Y; Lin, T; Shi, C; Wang, W; Yin, M; Zhao, X; Zhou, X | 1 |
| Hassaan, PS; Issa, Y; Nassar, SZ; Zahran, N | 1 |
| Liu, J; Liu, YZ; Wang, F; Xiao, XN; Yi, X; Yuan, YT | 1 |
| Bi, J; Cheng, K; Fan, J; Gao, H; Lin, Y; Ruan, L; Wang, T; Yan, Y; Yao, X; Zhang, W | 1 |
| Cao, MJ; Gu, W; Han, J; Liu, B; Liu, GM; Liu, H; Liu, QM; Shu, ZD; Yang, XW; Zhang, YF | 1 |
| Jia, L; Liu, F; Lu, F; Sang, J; Wang, W; Wang, Y; Wei, W; Zhao, F; Zhao, W | 1 |
| Gao, Y; Ge, H; Guan, S; Hao, Y; He, L; Huang, R; Liu, L; Shen, Y; Sun, M; Xiong, W; Yin, C | 1 |
| Bai, X; Guo, L; Luo, Q; Tan, K | 1 |
| Chen, X; Luo, Y; Wang, F; Yi, Y; Yuan, D | 1 |
| Huang, S; Jin, R; Li, X; Tan, L; Tong, H; Zhang, X | 1 |
| Adylova, A; Alhewairini, SS; Attar, R; Avnioglu, S; Buha, A; Fayyaz, S; Pawlak-Adamska, E; Qureshi, MZ; Sabitaliyevich, UY; Salahuddin, H; Tahir, F | 1 |
| Chen, XB; DU, JL; Wang, FJ; Wang, WS; Yuan, DP; Zong, XY | 1 |
| Chen, Y; Cheng, Y; Huang, Q; Wei, Z; Wijaya, W; Xiao, J | 1 |
| Cao, T; Guo, CH; Waddington, JL; Zhen, XC; Zheng, LT | 1 |
| Guo, H; Lin, H; Lin, N; Lu, W; Meng, L; Ni, T; Sun, Z; Zhang, C; Zhang, J | 1 |
| Abdulla, SA; Ardah, MT; El-Agnaf, OMA; Eliezer, D; Emara, MM; Ghanem, SS; Li, M; Lu, JH; Lv, G; Paleologou, KE; Vaikath, NN; Vekrellis, K | 1 |
| Chi, J; Guo, H; Lin, H; Lin, N; Lu, W; Ni, T; Sun, Z | 1 |
| Hua, YQ; Wang, W; Xu, XL; Zeng, Y; Zhang, H | 1 |
| Cao, M; Cao, Z; Faruque, MO; Hu, X; Jia, C; Li, J; Li, X; Liu, C; Ma, W; Zhang, M | 1 |
| Li, BR; Wang, L; Xiao, ZY; Yu, XD; Zhao, JL | 1 |
| Bhatti, AA; Davies, DL; Folk, C; Kim, P; Liang, J; Moradian, R; Silva, J; Spatz, MH; Yu, X | 1 |
| Chen, L; Deng, X; Deng, Y; He, G; He, J; Jiang, P; Kuang, D; Li, J; Li, R; Luo, J; Luo, S; Tan, S; Yan, M; Yang, D; Yang, Z; Yuan, Q; Zhou, Y; Zou, Y | 1 |
| Dergacheva, DI; Deryabina, YI; Gessler, NN; Isakova, EP; Klein, OI; Nikolaev, AV | 1 |
| Ding, L; Liu, D; Luo, J; Wang, H; Zeng, XA | 1 |
| Cao, C; Chang, Y; Li, C; Li, R; Liu, F; Liu, J; Muhammad, I; Shi, C; Yuan, L; Zhang, Y | 1 |
| Dong, T; Huang, M; Jiang, M; Lv, J; Wu, M; Xu, L; Xue, M | 1 |
| Feng, SD; He, JQ; Ling, HY; Luo, JD; Lyu, HJ; Wu, D; Yang, SS | 1 |
| Su, H; Sun, CC; Wang, WJ; Yuan, E; Zhang, QF; Zheng, GD | 1 |
| Cai, Q; Fan, KJ; Wang, QS; Wang, TY; Wu, J; Xu, BX | 1 |
| An, MQ; An, TT; Bao, GH; Dai, QY; Ke, JP; Kong, YS; Li, DX; Li, RZ; Ling, TJ; Liu, LL; Liu, R; Long, YH; Melnik, AV; Nothias, LF; Wan, XC; Xie, HF; Xie, ZW; Yang, Z; Zhang, H; Zhang, L; Zhang, P; Zhao, M | 1 |
| Chen, K; He, X; Hou, DX; Sakao, K; Xie, K | 1 |
| Alavi, MS; Etemad, L; Farkhari, H; Roohbakhsh, A | 1 |
| Hu, F; Hu, J; Lin, H; Wei, Q; Yang, X; Zhou, R | 1 |
| Cheng, R; Cheng, Z; He, Z; Huang, J; Liao, X; Niu, B; Shen, GX; Wang, S; Wu, X | 1 |
| Basu, S; Das, S; Majumder, T; Mukherjee, P; Sarkar, A | 1 |
| Cadenas, E; Chang, A; Davies, DL; Folk, C; Liang, J; Silva, J; Spatz, MH | 1 |
| Chen, J; Deng, B; Liao, P; Long, H; Ni, X; Sindaye, D; Xiao, Z; Xin, Z; Yang, K; Zhai, Z; Zhang, F; Zhang, L | 1 |
| Dalcin, AJF; Felin, S; Gomes, P; Mitjans, M; Ourique, AF; Roggia, I; Schuch, AP; Vinardell, MP; Vizzotto, BS | 1 |
| Geng, S; Jiang, Z; Liang, G; Liu, B; Ma, H; Pu, P | 1 |
| Fang, JG; Gao, SQ; Gong, YS; Lin, T; Shi, CY; Tong, S; Wang, WQ; Xiong, W; Zhou, HY | 1 |
| Chen, CH; Cheng, QC; Deng, XW; Ding, HR; Fan, J; Fang, X; Liu, HC; Wang, JW; Zhang, WG | 1 |
| Cui, L; Fan, X; Fan, Z; Gao, Y; Li, D; Li, Y; Mao, X; Ni, Q; Song, W; Wang, T; Wu, Q; Yang, D; Yang, M; Zeng, B; Zeng, Y; Zhang, M | 1 |
| Cui, S; He, K; Kang, S; Li, T; Liang, H; Ma, W; Song, L; Tang, M | 1 |
| Li, Y; Sun, CC; Yin, ZP; Zhang, QF | 1 |
| Azami, NLB; Fang, Z; Feng, Y; Li, Q; Sun, M; Sun, X; Wang, Y; Wang, Z; Zhang, L | 1 |
| Cai, T; Ge, F; Qi, S; Qi, Z; Wang, S | 1 |
| Du, Y; Pang, J; Xie, W; Yuan, S | 1 |
| Boštíková, Z; Boubínová, G; Dušková, Š; Hodek, P; Kutinová-Canová, N; Mráz, J; Skotnicová, A; Šulc, M | 1 |
| Chen, KL; Qian, Y; Sun, XF; Wang, HL; Xing, GD; Zhong, JF | 1 |
| Bao, S; Li, R; Ren, Q; Xu, X; Ye, J; Zhang, Q; Zhao, S; Zhu, Y | 1 |
| Chen, L; Liu, S; Lu, X; Lv, C; Qin, S; Shi, M; Song, Y; Wu, Y; Zheng, Z | 1 |
| Wang, J; Zeng, T; Zhang, H; Zhang, Q | 1 |
| Geng, S; Liang, G; Liu, B; Liu, X; Ma, H | 1 |
| Carry, E; Davies, DL; Liang, J; Roberge, JY; Silva, J; Xue, C; Zhang, J | 1 |
| Baker, MR; Hu, CY; Lei, J; Li, QX; Liang, Z; Liu, S; Pan, D; Sun, B; Tan, D; Wang, Z | 1 |
| Cheng, L; Ma, X; Wang, X; Xu, H; Yang, Y; Zhang, D | 1 |
| Cao, J; Chen, X; Lu, C; Qian, J; Wang, X; Zhang, W | 1 |
| Ding, H; Huang, B; Li, CH; Lin, HG; Luo, GQ; Shi, JL; Zeng, JC; Zhao, Y | 1 |
| Li, Y; Liu, L; Lou, B; Zhang, M; Zhang, Y | 1 |
| Chen, D; Chen, H; Chen, X; Guo, Z; Huang, Z; Luo, Y; Yan, H; Yu, B; Yu, J; Zheng, P | 1 |
| Chang, TM; Hsiao, TC; Huang, HC; Yang, TY | 1 |
| Dai, W; Jiang, L; Li, M; Li, Z; Yang, Y; Ye, WC | 1 |
| Chou, CH; Hsieh, YH; Lin, CW; Lu, KH; Yang, JS; Yang, SF | 1 |
| Dong, S; Hu, L; Jing, W; Lu, H; Wang, K; Wang, S; Zhao, X; Zhu, M | 1 |
| Ge, GB; Guan, XQ; Hu, Q; Qin, XY; Tang, H; Wang, HN; Xiang, YW; Xiong, Y; Yu, HN; Zhang, YN; Zhu, GH | 1 |
| Bi, Y; Chen, J; Fu, J; Liu, B; Wang, X; Xia, T; Zhu, R | 1 |
| Feng, XY; Jiang, CY; Wu, SX; Yu, ZW; Zhang, N | 1 |
| Bao, J; Cui, M; Gao, D; Li, D; Li, M; Li, X; Lin, J; Ren, S; Ruan, H; Sun, R; Wang, M; Wei, Y; Xiao, T; Yang, C; Zhang, L; Zhou, H | 1 |
| Chen, X; Huo, Y; Li, H; Liu, Y; Ma, W; Shi, P; Tian, X; Wang, H; Xie, L; Zhang, J | 1 |
| Duan, J; Liu, S; Lu, A; Sun, W; Yang, F | 1 |
| Chen, M; Feng, L; Li, Z; Ou, C; Que, D; Wei, J; Yan, J; Yang, P; Zhang, X; Zhong, X | 1 |
| Cai, G; Hou, L; Hu, CY; Huang, B; Jiang, F; Jiang, Y; Liu, D; Wang, C; Zheng, W | 2 |
| Geng, S; Li, Y; Liang, G; Liu, B; Lv, J; Ma, H | 1 |
| Chen, D; Chen, H; Chen, X; Guo, Z; He, J; Huang, Z; Luo, Y; Yan, H; Yu, B; Yu, J; Zheng, P | 1 |
| Dinda, AK; Joshi, B; Reeta, KH; Sharma, U; Singh, D; Upadhyay, D; Wasan, H | 1 |
| Frankova, J; Hodek, P; Sklenarova, R; Svrckova, M; Ulrichova, J | 1 |
| Chen, JG; Chen, LL; Li, JE; Sun, CC; Wang, WJ; Yin, ZP; Zhang, QF; Zheng, GD | 1 |
| Al Omran, AJ; Davies, DL; Liang, J; Shao, AS; Shao, XM; Watanabe, J; Watanabe, S; Xue, C; Zhang, J; Zhang, Z | 1 |
| Arroo, R; Bajpai, VK; Cao, H; Chen, XJ; Högger, P; Prieto, MA; Simal-Gandara, J; Wang, ML; Yi, LZ; Zhang, HL | 1 |
| Ishfaq, M; Li, C; Li, R; Li, Y; Liu, F; Shi, C; Si, C; Wang, J; Zhang, R | 1 |
| Ji, X; Jiang, Y; Peng, F; Tao, X; Zheng, X | 1 |
| Chen, J; Hu, Y; Li, Y; Qi, K; Wang, R; Wei, Y | 1 |
| Ho, YT; Hsin, CH; Huang, CC; Lin, CW; Lu, YT; Su, CW; Wang, PH; Yang, SF | 1 |
| Ding, P; Ji, G; Wang, J; Wang, Y; Wu, T; Xiang, H | 1 |
| Chen, D; Chen, X; Guo, Z; He, J; Huang, Z; Li, M; Luo, Y; Yan, H; Yu, B; Zheng, P | 1 |
| Li, W; Lin, R; Liu, H; Meng, X; Nan, G; Shi, B; Yang, G; Zheng, S | 1 |
| Csoka, AB; Getachew, B; Tizabi, Y | 1 |
| Davies, DL; Liang, J; Omran, AA; Shao, AS; Shao, XM; Watanabe, J; Watanabe, S; Xue, C; Zhang, J; Zhang, Z | 1 |
| Cai, X; Cui, P; Ge, S; Tan, J; Xue, H; Zhang, G | 1 |
| Cao, H; Chen, L; Lin, S; Lyu, Q; Teng, H | 1 |
| Hou, P; Mi, M; Yao, Y; Yi, L; Yue, J; Zhang, Q; Zhou, J | 1 |
| Liu, Q; Liu, S; Peng, Q; Wang, J; Zhang, Y | 1 |
| Ahmed, AF; Amin, AH; Awad, EM; El-Daly, M; El-Tahawy, NFG; Hollenberg, MD; Taye, A; Wagdy, A | 1 |
| Cheng, Z; Ding, C; Ding, Q; Liu, W; Liu, X; Peng, X; Sun, S; Zhao, Y; Zheng, Y | 1 |
| Chen, D; Chen, H; Chen, X; He, J; Huang, Z; Luo, Y; Wei, C; Yan, H; Yu, B; Zheng, P | 1 |
| Fu, Z; Huang, Y; Luo, F; Ren, Y; Shu, X; Wang, W | 1 |
| Huajian, L; Jiayu, Z; Jing, X; Pingping, D; Shan, J; Yifang, C; Yong, W | 1 |
| Chen, X; Dong, M; Lou, Y; Lu, J; Mi, X; Zhan, X | 1 |
| Li, P; Liu, T; Wang, D; Xie, J; Xu, S; Zhang, T | 1 |
| Liu, H; Shi, H; Zhang, D; Zhang, H; Zhang, R; Zhang, Z | 1 |
| Chen, D; Chen, H; Chen, X; Guo, Z; He, J; Huang, Z; Luo, Y; Yan, H; Yu, B; Zheng, P | 1 |
| Awad, EM; El-Sheikh, AAK; El-Tahawy, NFG; Matouk, AI; Waz, S | 1 |
| Gong, H; Li, M; Xu, H; Zhang, D | 1 |
| Lang, H; Li, T; Mi, M; Wu, L; Xie, Y; Yi, L; Zhang, Q; Zhou, M | 1 |
| Chen, D; Fu, J; Ji, T; Nie, H; Tang, Z; Zhang, C | 1 |
| Chen, PN; Hsiao, YH; Hsin, MC; Lee, CY; Lin, CW; Wang, PH; Yang, SF | 1 |
| Chen, Y; Gao, S; Xu, S; Yu, S; Zhang, S; Zhou, J | 1 |
| Hou, P; Lang, H; Mi, M; Wang, D; Yao, Y; Yi, L; Zhou, J; Zhou, M; Zhu, J | 1 |
| Bi, J; Guo, L; Han, C; He, Z; Pei, H | 1 |
| Chen, S; Fu, X; Li, C; Li, S; Liu, H; Shi, H; Shi, J; Tian, Y; Wang, S; Wang, Y; Wu, A; Zhang, C; Zhang, D; Zhang, H; Zhang, R | 1 |
| Gao, Y; Heng, W; Lu, Y; Qian, S; Wei, Y; Xia, Y; Zhang, J | 1 |
| Cao, Z; Wang, Z; Yang, Z; Yue, Z | 1 |
| Arroo, RRJ; Chen, X; Farag, MA; Hussain, H; Lin, S; Wang, H; Xiao, J; Xie, R; Zhang, H; Zhong, W | 1 |
8 review(s) available for ampelopsin and 3-hydroxyflavone
| Article | Year |
|---|---|
Multitarget and promising role of dihydromyricetin in the treatment of metabolic diseases.
Topics: Animals; Atherosclerosis; Diabetes Mellitus; Flavonols; Gene Expression Regulation; Humans; Hypoglycemic Agents; Metabolic Diseases; Non-alcoholic Fatty Liver Disease; Osteoporosis; Signal Transduction | 2020 |
Dihydromyricetin Acts as a Potential Redox Balance Mediator in Cancer Chemoprevention.
Topics: Animals; Anti-Inflammatory Agents; Flavonols; Humans; Neoplasms; Oxidative Stress | 2021 |
Molecular mechanisms and therapeutic implications of dihydromyricetin in liver disease.
Topics: Carcinoma, Hepatocellular; Flavonols; Humans; Liver Diseases; Liver Diseases, Alcoholic; Liver Failure, Acute; Liver Neoplasms; Liver Regeneration; Non-alcoholic Fatty Liver Disease; Protective Agents | 2021 |
Recent update on application of dihydromyricetin in metabolic related diseases.
Topics: AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Antioxidants; Cell Death; Flavonols; Glucose; Humans; Lipid Metabolism; Liver Diseases; Metabolic Diseases; MicroRNAs; Neoplasms; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2022 |
Strategic developments in the drug delivery of natural product dihydromyricetin: applications, prospects, and challenges.
Topics: Biological Products; Drug Delivery Systems; Flavonols; Pharmaceutical Preparations | 2022 |
Molecular mechanism and therapeutic significance of dihydromyricetin in nonalcoholic fatty liver disease.
Topics: Flavonols; Humans; Lipid Metabolism; Liver; Non-alcoholic Fatty Liver Disease | 2022 |
Molecular mechanisms and promising role of dihydromyricetin in cardiovascular diseases.
Topics: Cardiovascular Diseases; Flavonols; Humans; Oxidative Stress; Tea | 2022 |
Research progress of dihydromyricetin in the treatment of diabetes mellitus.
Topics: Diabetes Mellitus; Flavonols; Humans; Hyperglycemia; Phosphatidylinositol 3-Kinases | 2023 |
2 trial(s) available for ampelopsin and 3-hydroxyflavone
| Article | Year |
|---|---|
Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial.
Topics: Adult; Ampelopsis; Biomarkers; Double-Blind Method; Female; Flavonols; Glucose; Humans; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Plants, Medicinal | 2015 |
Dihydromyricetin improves meat quality and promotes skeletal muscle fiber type transformations
Topics: AMP-Activated Protein Kinases; Animal Feed; Animals; Body Composition; Diet; Flavonols; Meat; Muscle Fibers, Skeletal; Muscle, Skeletal; Swine | 2022 |
248 other study(ies) available for ampelopsin and 3-hydroxyflavone
| Article | Year |
|---|---|
Purification of (+)-dihydromyricetin from leaves extract of Ampelopsis grossedentata using high-speed countercurrent chromatograph with scale-up triple columns.
Topics: Ampelopsis; Chromatography, High Pressure Liquid; Countercurrent Distribution; Flavonoids; Flavonols; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Extracts; Plant Leaves | 2002 |
[Determination of total flavonoids and dihydromyricetin in Ampelopsis grossedentala (Hand-Mazz) W. T. Wang].
Topics: Ampelopsis; Flavonoids; Flavonols; Plant Leaves; Plant Stems; Plants, Medicinal | 2000 |
[Studies on the chemical constituents from Ampelopsis grossedentata].
Topics: Ampelopsis; Drugs, Chinese Herbal; Flavonoids; Flavonols; Molecular Structure; Plant Leaves; Plants, Medicinal; Quercetin; Sitosterols; Spectrophotometry, Ultraviolet; Spectroscopy, Near-Infrared; Stigmasterol | 2002 |
Antioxidation properties and mechanism of action of dihydromyricetin from Ampelopsis grossedentata.
Topics: Ampelopsis; Antioxidants; Chelating Agents; Flavonols; Free Radical Scavengers; Lipid Peroxidation; Molecular Structure; Plants, Medicinal | 2003 |
[Studies on the effect of dihydromyricetin on antilipid-peroxidation].
Topics: Ampelopsis; Animals; Antioxidants; Brain; Dose-Response Relationship, Drug; Flavonols; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mitochondria; Mitochondrial Swelling; Myocardium; Plants, Medicinal; Rats | 2003 |
Isolation and identification of metabolites from dihydromyricetin.
Topics: Animals; Chromatography, High Pressure Liquid; Flavonols; Glucuronides; Male; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet | 2007 |
Simultaneous determination and pharmacokinetic studies of dihydromyricetin and myricetin in rat plasma by HPLC-DAD after oral administration of Ampelopsis grossedentata decoction.
Topics: Administration, Oral; Ampelopsis; Animals; Chromatography, High Pressure Liquid; Drug Stability; Flavonoids; Flavonols; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity | 2007 |
Structure-activity relationship of flavonoids active against lard oil oxidation based on quantum chemical analysis.
Topics: Antioxidants; Dietary Fats; Flavonoids; Flavonols; Hydrogen; Kaempferols; Luteolin; Molecular Structure; Oils; Oxidation-Reduction; Quantum Theory; Quercetin; Structure-Activity Relationship | 2008 |
Excision of an active CACTA-like transposable element from DFR2 causes variegated flowers in soybean [Glycine max (L.) Merr.].
Topics: Alcohol Oxidoreductases; Alleles; Alternative Splicing; Amino Acid Sequence; Anthocyanins; Base Sequence; Conserved Sequence; DNA Transposable Elements; Flavonols; Flowers; Genetic Loci; Glucosides; Glycine max; Introns; Molecular Sequence Data; Mutation; Phenotype; Promoter Regions, Genetic; RNA, Messenger; Transposases | 2010 |
[Effect of serum containing tengcha total flavonoid and dihydromyricetin on proliferation and apoptosis of HepG2 cells].
Topics: Ampelopsis; Animals; Apoptosis; Cell Proliferation; Flavonoids; Flavonols; Hep G2 Cells; Humans; Male; Rats; Rats, Wistar | 2011 |
Molecular characterization and expression analysis of dihydroflavonol 4-reductase (DFR) gene in Saussurea medusa.
Topics: Alcohol Oxidoreductases; Base Sequence; Chromatography, High Pressure Liquid; Computational Biology; DNA Primers; DNA, Complementary; Endangered Species; Escherichia coli; Flavonoids; Flavonols; Flowers; Gene Expression Profiling; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Phylogeny; Quercetin; Real-Time Polymerase Chain Reaction; Saccharomyces cerevisiae; Saussurea; Sequence Analysis, DNA | 2012 |
Electrochemical detection of dihydromyricetin using a DNA immobilized ethylenediamine/polyglutamic modified electrode.
Topics: Ampelopsis; Chromatography, High Pressure Liquid; DNA; Electrochemistry; Electrodes; Ethylenediamines; Flavonols; Limit of Detection; Oxidation-Reduction; Polyglutamic Acid | 2012 |
Dihydromyricetin as a novel anti-alcohol intoxication medication.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholic Intoxication; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Flavonols; Male; Pregnancy; Primary Cell Culture; Rats; Rats, Sprague-Dawley | 2012 |
Probing the interaction of anti-cancer agent dihydromyricetin with human serum albumin: a typical method study.
Topics: Antineoplastic Agents, Phytogenic; Binding Sites; Biological Products; Flavonols; Humans; Molecular Structure; Serum Albumin; Thermodynamics | 2012 |
Binding of dihydromyricetin to human hemoglobin: fluorescence and circular dichroism studies.
Topics: Ampelopsis; Circular Dichroism; Flavonols; Hemoglobins; Humans; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence | 2012 |
[Effects of dihydromyricetin on tumor necrosis factor and NF-kappaB p65 of RAU rats].
Topics: Animals; Disease Models, Animal; Female; Flavonols; Humans; Macrophages; Male; Mouth Mucosa; Rats; Rats, Sprague-Dawley; Stomatitis, Aphthous; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2012 |
Simultaneous determination of dihydromyricetin and resveratrol in Ampelopsis sinica (Miq.) W.T. Wang by high-performance liquid chromatography coupled with a diode array detection method.
Topics: Ampelopsis; Chromatography, High Pressure Liquid; Drug Stability; Drugs, Chinese Herbal; Flavonols; Limit of Detection; Linear Models; Reproducibility of Results; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes | 2014 |
Interaction of dihydromyricetin and alpha-amylase.
Topics: alpha-Amylases; Binding Sites; Flavonols | 2013 |
Dihydromyricetin suppresses the proliferation of hepatocellular carcinoma cells by inducing G2/M arrest through the Chk1/Chk2/Cdc25C pathway.
Topics: Carcinoma, Hepatocellular; cdc25 Phosphatases; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Flavonols; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Protein Kinases; Signal Transduction | 2013 |
Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma HepG2 cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Proliferation; Down-Regulation; Drug Screening Assays, Antitumor; Flavonols; Hep G2 Cells; Humans; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Suppressor Protein p53 | 2013 |
Dihydromyricetin induces autophagy in HepG2 cells involved in inhibition of mTOR and regulating its upstream pathways.
Topics: Autophagy; Cell Proliferation; Flavonols; Hep G2 Cells; Humans; Microscopy, Electron, Transmission; Phosphorylation; TOR Serine-Threonine Kinases | 2014 |
Dihydromyricetin improves physical performance under simulated high altitude.
Topics: Altitude; Animals; Biomarkers; Blood Urea Nitrogen; Creatine Kinase; DNA, Mitochondrial; Dose-Response Relationship, Drug; Electron Transport; Exercise Test; Exercise Tolerance; Flavonols; Hypoxia; L-Lactate Dehydrogenase; Male; Mitochondria; Mitochondrial Dynamics; Muscle, Skeletal; Rats, Sprague-Dawley; Up-Regulation | 2014 |
Dihydromyricetin prevents fetal alcohol exposure-induced behavioral and physiological deficits: the roles of GABAA receptors in adolescence.
Topics: Age Factors; Animals; Animals, Newborn; Anxiety; Dose-Response Relationship, Drug; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Flavonols; Hippocampus; Male; Organ Culture Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Potentials | 2014 |
Inhibition of catechol-o-methyltransferase (COMT) by myricetin, dihydromyricetin, and myricitrin.
Topics: Catechol O-Methyltransferase Inhibitors; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Flavonols; Humans; Indicators and Reagents; Kinetics; Levodopa; Liver; Methylation; Structure-Activity Relationship | 2014 |
Dihydromyricetin promotes hepatocellular carcinoma regression via a p53 activation-dependent mechanism.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cisplatin; Enzyme Activation; Flavonols; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; RNA Interference; RNA, Small Interfering; Signal Transduction; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2014 |
Dihydromyricetin ameliorates behavioral deficits and reverses neuropathology of transgenic mouse models of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Anxiety; Cognition Disorders; Disease Models, Animal; Flavonols; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2014 |
Dihydromyricetin induces cell cycle arrest and apoptosis in melanoma SK-MEL-28 cells.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Flavonols; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Neoplasm Proteins | 2014 |
Recrystallization of dihydromyricetin from Ampelopsis grossedentata and its anti-oxidant activity evaluation.
Topics: Adult; Amidines; Ampelopsis; Antioxidants; Catalase; Chromatography, High Pressure Liquid; Crystallization; Erythrocytes; Flavonols; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Microscopy, Electron, Scanning; Reactive Oxygen Species; Superoxide Dismutase; Temperature; Time Factors | 2014 |
Dihydromyricetin activates AMP-activated protein kinase and P38(MAPK) exerting antitumor potential in osteosarcoma.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Flavonols; Fluorescent Antibody Technique; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Real-Time Polymerase Chain Reaction; Signal Transduction; Xenograft Model Antitumor Assays | 2014 |
Dihydromyricetin inhibits migration and invasion of hepatoma cells through regulation of MMP-9 expression.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Flavonols; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Phosphorylation; Protein Kinase C-delta; Signal Transduction; Time Factors | 2014 |
A potent antibrowning agent from pine needles of Cedrus deodara: 2R,3R-dihydromyricetin.
Topics: Antioxidants; Ascorbic Acid; Cedrus; Flavonols; Food Storage; Fruit; Fungal Proteins; Maillard Reaction; Malus; Monophenol Monooxygenase; Plant Extracts | 2014 |
Dihydromyricetin prevents cardiotoxicity and enhances anticancer activity induced by adriamycin.
Topics: Animals; Animals, Newborn; Antibiotics, Antineoplastic; Apoptosis; Cell Proliferation; Cytoprotection; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Doxorubicin; Flavonols; Heart Diseases; HL-60 Cells; Humans; K562 Cells; Lymphoma, Large B-Cell, Diffuse; Mice, Inbred BALB C; Mice, Inbred ICR; Myocytes, Cardiac; Nerve Tissue Proteins; Oxidative Stress; Protective Agents; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Tumor Burden; Tumor Suppressor Protein p53; U937 Cells; Xenograft Model Antitumor Assays | 2015 |
Dihydromyricetin induces mouse hepatoma Hepal-6 cell apoptosis via the transforming growth factor-β pathway.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Flavonols; Liver Neoplasms; Mice; Models, Biological; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta | 2015 |
A reduction in reactive oxygen species contributes to dihydromyricetin-induced apoptosis in human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Flavonols; Hep G2 Cells; Humans; Hydrogen Peroxide; Mitochondria; Reactive Oxygen Species; Signal Transduction | 2014 |
Antioxidant activities of Vine Tea (Ampelopsis grossedentata) extract and its major component dihydromyricetin in soybean oil and cooked ground beef.
Topics: Ampelopsis; Animals; Antioxidants; Butylated Hydroxyanisole; Cattle; Chromatography, High Pressure Liquid; Flavonols; Meat; Oxidation-Reduction; Phenols; Plant Extracts; Soybean Oil | 2015 |
Dihydromyricetin ameliorates the oxidative stress response induced by methylglyoxal via the AMPK/GLUT4 signaling pathway in PC12 cells.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Calcium; Cell Membrane; Cell Survival; Dose-Response Relationship, Drug; Flavonols; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Glutathione; In Situ Nick-End Labeling; Lactic Acid; Oxidative Stress; PC12 Cells; Pyruvaldehyde; Rats; Reactive Oxygen Species; Signal Transduction | 2014 |
[Protective effect and mechanisms of dihydromyricetin on PC12 cells induced by oxidative injury].
Topics: Animals; Apoptosis; Blotting, Western; Cytoprotection; Flavonols; Nitroprusside; Oxidative Stress; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Signal Transduction | 2014 |
Attenuating effects of dihydromyricetin on angiotensin II-induced rat cardiomyocyte hypertrophy related to antioxidative activity in a NO-dependent manner.
Topics: Angiotensin II; Animals; Animals, Newborn; Antioxidants; Cell Size; Cell Survival; Cyclic GMP; Flavonols; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type III; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2015 |
Effect of dihydromyricetin on benzo[a]pyrene activation in rats.
Topics: Animals; Benzo(a)pyrene; Carcinogens; DNA Adducts; Flavonols; Male; Rats; Rats, Wistar | 2014 |
Highly efficient and regioselective synthesis of dihydromyricetin esters by immobilized lipase.
Topics: Acylation; Enzymes, Immobilized; Flavonols; Lipase; Stereoisomerism | 2015 |
Dihydromyricetin improves skeletal muscle insulin resistance by inducing autophagy via the AMPK signaling pathway.
Topics: Adenine; AMP-Activated Protein Kinases; Animals; Autophagy; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Flavonols; Gene Expression Regulation; Insulin Resistance; Macrolides; Male; Muscle, Skeletal; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2015 |
Dihydromyricetin protects endothelial cells from hydrogen peroxide-induced oxidative stress damage by regulating mitochondrial pathways.
Topics: Antioxidants; Apoptosis; Cell Survival; Flavonols; Flow Cytometry; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Malondialdehyde; Microscopy, Fluorescence; Mitochondria; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase | 2015 |
Dihydromyricetin improves skeletal muscle insulin sensitivity by inducing autophagy via the AMPK-PGC-1α-Sirt3 signaling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Flavonols; Insulin Resistance; Male; Mice; Mice, 129 Strain; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction; Sirtuin 3; Transcription Factors | 2015 |
Dihydromyricetin Enhances the Chemo-Sensitivity of Nedaplatin via Regulation of the p53/Bcl-2 Pathway in Hepatocellular Carcinoma Cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Flavonols; Humans; Liver Neoplasms; Organoplatinum Compounds; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53 | 2015 |
Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Catechin; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonols; Humans; Methylation; Models, Molecular; Molecular Structure; Neoplasm Proteins; Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2015 |
Dihydromyricetin alleviates carbon tetrachloride-induced acute liver injury via JNK-dependent mechanism in mice.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Carbon Tetrachloride; Caspase Inhibitors; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cytochromes c; Disease Models, Animal; Flavonols; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Liver; Liver Failure, Acute; Liver Regeneration; Male; Mice, Inbred C57BL; Mitochondria, Liver; Protein Kinase Inhibitors; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 2015 |
Dihydromyricetin stimulates irisin secretion partially via the PGC-1α pathway.
Topics: Animals; Antimetabolites; Cells, Cultured; Fibronectins; Flavonols; Humans; Male; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Sprague-Dawley; Transcription Factors | 2015 |
Determination of dihydromyricetin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study.
Topics: Acetonitriles; Administration, Oral; Animals; Area Under Curve; Calibration; Chromatography, Liquid; Drugs, Chinese Herbal; Female; Flavonols; Hemolysis; Male; Mass Spectrometry; Oxygen; Plasma; Quality Control; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Temperature; Water | 2015 |
Suppression of Inflammatory Responses by Dihydromyricetin, a Flavonoid from Ampelopsis grossedentata, via Inhibiting the Activation of NF-κB and MAPK Signaling Pathways.
Topics: Ampelopsis; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; Flavonoids; Flavonols; I-kappa B Proteins; Interleukin-10; Interleukin-1beta; Interleukin-6; Macrophages; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Structure; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Signal Transduction; Tumor Necrosis Factor-alpha | 2015 |
Mutation of cysteine 46 in IKK-beta increases inflammatory responses.
Topics: Animals; Arthritis, Experimental; Cells, Cultured; Collagen Type II; Cysteine; Female; Flavonols; Flow Cytometry; Fluorescent Antibody Technique; Humans; Hypersensitivity, Delayed; I-kappa B Kinase; Immunoenzyme Techniques; Inflammation; Mice; Mice, Transgenic; Mutation; NF-kappa B; Phosphorylation; Rats; Rats, Wistar; Signal Transduction; T-Lymphocytes | 2015 |
Dihydromyricetin induces cell apoptosis via a p53-related pathway in AGS human gastric cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Flavonols; Gene Expression Regulation, Neoplastic; Humans; Signal Transduction; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2015 |
Dihydromyricetin Improves Hypobaric Hypoxia-Induced Memory Impairment via Modulation of SIRT3 Signaling.
Topics: Acetylation; Adenosine Triphosphate; Animals; ATP Synthetase Complexes; Body Weight; Cell Line; Flavonols; Forkhead Box Protein O3; Hippocampus; Hypoxia; Male; Maze Learning; Memory Disorders; Mice; Mitochondria; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 3; Synapses | 2016 |
Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation.
Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Flavonols; Inhibitory Concentration 50; Intestine, Small; Liver; Male; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2015 |
Protective Effect of Dihydromyricetin Against Lipopolysaccharide-Induced Acute Kidney Injury in a Rat Model.
Topics: Acute Kidney Injury; Animals; Calcium; Creatinine; Disease Models, Animal; Drug Interactions; Endotoxemia; Flavonols; Hyaluronan Receptors; Kidney; Lipopolysaccharides; Male; Osteopontin; Random Allocation; Rats; Rats, Sprague-Dawley | 2016 |
Protective Effects of Dihydromyricetin against •OH-Induced Mesenchymal Stem Cells Damage and Mechanistic Chemistry.
Topics: Animals; Antioxidants; Cell Survival; Flavonoids; Flavonols; Hydroxyl Radical; Mesenchymal Stem Cells; Rats | 2016 |
Apoptosis inhibition effect of Dihydromyricetin against UVA-exposed human keratinocyte cell line.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line; Cytokines; DNA Damage; Flavonols; Histones; Humans; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Oxidative Stress; Oxidoreductases; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Transcription Factor RelA; Ultraviolet Rays | 2016 |
Dihydromyricetin ameliorates oleic acid-induced lipid accumulation in L02 and HepG2 cells by inhibiting lipogenesis and oxidative stress.
Topics: Fatty Liver; Flavonols; Hep G2 Cells; Humans; Lipid Metabolism; Lipogenesis; Oleic Acid; Oxidative Stress | 2016 |
Dihydromyricetin protects neurons in an MPTP-induced model of Parkinson's disease by suppressing glycogen synthase kinase-3 beta activity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Line; Flavonols; Glycogen Synthase Kinase 3 beta; Male; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Protein Kinase Inhibitors; Rats | 2016 |
Solid-state characterization of optically pure (+)Dihydromyricetin extracted from Ampelopsis grossedentata leaves.
Topics: Ampelopsis; Calorimetry; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonols; Magnetic Resonance Spectroscopy; Plant Leaves; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2016 |
Dihydromyricetin enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells in vitro partially via the activation of Wnt/β-catenin signaling pathway.
Topics: Adaptor Proteins, Signal Transducing; Alkaline Phosphatase; beta Catenin; Bone and Bones; Bone Morphogenetic Proteins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Flavonoids; Flavonols; Genetic Markers; Humans; Intercellular Signaling Peptides and Proteins; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Wnt Signaling Pathway | 2016 |
Dihydromyricetin promotes autophagy and apoptosis through ROS-STAT3 signaling in head and neck squamous cell carcinoma.
Topics: Apoptosis; Autophagy; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Flavonols; Head and Neck Neoplasms; Humans; Phosphorylation; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor | 2016 |
Dihydromyricetin suppresses inflammatory responses in vitro and in vivo through inhibition of IKKβ activity in macrophages.
Topics: Animals; Anti-Inflammatory Agents; Female; Flavonols; HEK293 Cells; Humans; I-kappa B Kinase; Macrophages; Mice; Microscopy, Atomic Force; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; RAW 264.7 Cells; Transcription Factor RelA | 2016 |
Dihydromyricetin Ameliorates 3NP-induced Behavioral Deficits and Striatal Injury in Rats.
Topics: Animals; Apoptosis; Corpus Striatum; Flavonols; Locomotion; Male; Malondialdehyde; Maze Learning; Neurodegenerative Diseases; Neuroprotective Agents; Nitro Compounds; Oxidative Stress; Positron Emission Tomography Computed Tomography; Propionates; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2016 |
Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonols; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Protein Kinase Inhibitors; Reactive Oxygen Species | 2017 |
Optimization of the Ultrasonic-Assisted Extraction of Bioactive Flavonoids from Ampelopsis grossedentata and Subsequent Separation and Purification of Two Flavonoid Aglycones by High-Speed Counter-Current Chromatography.
Topics: Ampelopsis; Chromatography, Liquid; Countercurrent Distribution; Flavonoids; Flavonols; Molecular Structure; Plant Extracts; Plant Leaves; Ultrasonics | 2016 |
Dihydromyricetin from Ampelopsis grossedentata inhibits melanogenesis through down-regulation of MAPK, PKA and PKC signaling pathways.
Topics: Ampelopsis; Animals; Antioxidants; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Flavonols; Melanins; Melanoma, Experimental; Mice; Mitogen-Activated Protein Kinases; Protein Kinase C; Signal Transduction | 2016 |
Dihydromyricetin suppresses TNF-α-induced NF-κB activation and target gene expression.
Topics: Active Transport, Cell Nucleus; Apoptosis; Cell Nucleus; Flavonols; Gene Expression Regulation; HeLa Cells; Humans; I-kappa B Kinase; Nuclear Pore Complex Proteins; RNA-Binding Proteins; TNF Receptor-Associated Factor 2; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2016 |
A dual antibacterial mechanism involved in membrane disruption and DNA binding of 2R,3R-dihydromyricetin from pine needles of Cedrus deodara against Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Cedrus; Cell Membrane; DNA; Flavonols; Membrane Fluidity; Microbial Sensitivity Tests; Staphylococcus aureus | 2017 |
The cardioprotective effect of dihydromyricetin prevents ischemia-reperfusion-induced apoptosis in vivo and in vitro via the PI3K/Akt and HIF-1α signaling pathways.
Topics: Animals; Apoptosis; Cardiotonic Agents; Flavonols; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2016 |
[Reversal Effect of Dihydromyricetin on Drug Resistance of K562/A02 Cell Line to Adriamycin].
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonols; Humans; K562 Cells; Multidrug Resistance-Associated Proteins | 2016 |
Dihydromyricetin protects against liver ischemia/reperfusion induced apoptosis via activation of FOXO3a-mediated autophagy.
Topics: Animals; Apoptosis; Autophagy; Caspase 3; Disease Models, Animal; Flavonols; Forkhead Box Protein O3; Liver Diseases; Mice; Mice, Inbred C57BL; Phosphorylation; Protective Agents; Reperfusion Injury | 2016 |
Metabolomics reveals the protective of Dihydromyricetin on glucose homeostasis by enhancing insulin sensitivity.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Citric Acid Cycle; Diet, High-Fat; Flavonols; Glucose; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Hyperglycemia; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Metabolic Networks and Pathways; Protective Agents; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Up-Regulation | 2016 |
Dihydromyricetin delays the onset of hyperglycemia and ameliorates insulin resistance without excessive weight gain in Zucker diabetic fatty rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Progression; Flavonols; Hyperglycemia; Insulin Resistance; Male; Obesity; Rats; Rats, Zucker; Time Factors; Weight Gain | 2017 |
Dihydromyricetin reverses MRP2-mediated MDR and enhances anticancer activity induced by oxaliplatin in colorectal cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Colorectal Neoplasms; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Flavonols; HCT116 Cells; Humans; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; NF-E2-Related Factor 2; Organoplatinum Compounds; Oxaliplatin; Promoter Regions, Genetic | 2017 |
Gastrointestinal stability of dihydromyricetin, myricetin, and myricitrin: an in vitro investigation.
Topics: Biological Availability; Flavonoids; Flavonols; Gastrointestinal Tract; Humans; Hydrogen-Ion Concentration; Limit of Detection; Pancreatin; Pepsin A; Reproducibility of Results | 2017 |
Dihydromyricetin Reduces TGF-β Via P53 Activation-dependent Mechanism in Hepatocellular Carcinoma HepG2 Cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Flavonols; Hep G2 Cells; Humans; Transforming Growth Factor beta; Tumor Suppressor Protein p53 | 2017 |
Highly Efficient Enzymatic Acylation of Dihydromyricetin by the Immobilized Lipase with Deep Eutectic Solvents as Cosolvent.
Topics: Acylation; Aspergillus niger; Enzymes, Immobilized; Flavonols; Fungal Proteins; Lipase; Oxidation-Reduction | 2017 |
Dihydromyricetin prevents obesity-induced slow-twitch-fiber reduction partially via FLCN/FNIP1/AMPK pathway.
Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Dietary Fats; Flavonols; Gene Expression Regulation; Insulin Resistance; Male; Mice; Muscle Fibers, Slow-Twitch; Obesity; Proto-Oncogene Proteins; Signal Transduction; Tumor Suppressor Proteins | 2017 |
Dihydromyricetin induces mitochondria-mediated apoptosis in HepG2 cells through down-regulation of the Akt/Bad pathway.
Topics: Ampelopsis; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Caspase 3; Down-Regulation; Flavonols; Hep G2 Cells; Humans; Liver Neoplasms; Mitochondria; Phosphorylation; Plant Extracts; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2017 |
Anti‑inflammatory effects of dihydromyricetin in a mouse model of asthma.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Flavonols; Goblet Cells; Immunoglobulin E; Immunoglobulin G; Mice; Mucus; Ovalbumin | 2017 |
Dihydromyricetin modulates p62 and autophagy crosstalk with the Keap-1/Nrf2 pathway to alleviate ethanol-induced hepatic injury.
Topics: Animals; Autophagy; Biomarkers; Flavonols; Gene Expression Regulation; Interleukin-1beta; Interleukin-6; Kelch-Like ECH-Associated Protein 1; Lipid Peroxidation; Liver; Male; Mice, Inbred C57BL; NF-E2-Related Factor 2; Specific Pathogen-Free Organisms; Transcription Factor TFIIH; Transcription Factors | 2017 |
Dihydromyricetin Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Mice.
Topics: Animals; Apoptosis; Autophagy; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Flavonols; Inflammation; Male; Mice; Oxidative Stress | 2017 |
Dihydromyricetin Induces Apoptosis and Reverses Drug Resistance in Ovarian Cancer Cells by p53-mediated Downregulation of Survivin.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Shape; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Female; Flavonols; Humans; Inhibitor of Apoptosis Proteins; Ovarian Neoplasms; Paclitaxel; S Phase; Signal Transduction; Survivin; Tumor Suppressor Protein p53 | 2017 |
Dihydromyricetin induces apoptosis and cytoprotective autophagy through ROS-NF-κB signalling in human melanoma cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cytoprotection; Drug Screening Assays, Antitumor; Flavonols; Humans; Melanoma; NF-kappa B; Reactive Oxygen Species; Signal Transduction; Skin Neoplasms | 2017 |
Dihydromyricetin ameliorates atherosclerosis in LDL receptor deficient mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Aortic Diseases; Atherosclerosis; Cytokines; Diet, High-Fat; Disease Models, Animal; Flavonols; Foam Cells; Genetic Predisposition to Disease; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Lipoproteins, LDL; Liver; Male; Mice; Mice, Knockout; Oxidative Stress; Phenotype; Plaque, Atherosclerotic; RAW 264.7 Cells; Receptors, LDL | 2017 |
Tissue Distribution, Excretion, and Metabolic Profile of Dihydromyricetin, a Flavonoid from Vine Tea (Ampelopsis grossedentata) after Oral Administration in Rats.
Topics: Ampelopsis; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Feces; Flavonols; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution | 2017 |
Anti biofilm effect of dihydromyricetin-loaded nanocapsules on urinary catheter infected by Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Biofilms; Flavonols; Microbial Sensitivity Tests; Nanocapsules; Particle Size; Pseudomonas aeruginosa; Pseudomonas Infections; Urinary Catheters | 2017 |
Dihydromyricetin protects human umbilical vein endothelial cells from injury through ERK and Akt mediated Nrf2/HO-1 signaling pathway.
Topics: Apoptosis; Atherosclerosis; Cell Survival; Flavonols; Flow Cytometry; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; MAP Kinase Signaling System; NF-E2-Related Factor 2; Oncogene Protein v-akt; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Signal Transduction | 2017 |
An inhibition mechanism of dihydromyricetin on tyrosinase and the joint effects of vitamins B
Topics: Amino Acid Motifs; Binding Sites; Cholecalciferol; Enzyme Inhibitors; Flavonols; Kinetics; Molecular Docking Simulation; Monophenol Monooxygenase; Vitamin B 6; Vitamin E | 2017 |
Effects of verapamil on the pharmacokinetics of dihydromyricetin in rats and its potential mechanism.
Topics: Administration, Intravenous; Administration, Oral; Animals; Caco-2 Cells; Flavonols; Humans; Male; Rats; Rats, Sprague-Dawley; Verapamil | 2018 |
Unraveling the inhibitory effect of dihydromyricetin on heterocyclic aromatic amines formation.
Topics: Amines; Animals; Cattle; Cooking; Flavonols; Heterocyclic Compounds; Hot Temperature; Meat; Red Meat | 2018 |
Dihydromyricetin-mediated inhibition of the Notch1 pathway induces apoptosis in QGY7701 and HepG2 hepatoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Proliferation; Disease Progression; Down-Regulation; Flavonols; Flow Cytometry; Hep G2 Cells; Humans; Liver Neoplasms; Proto-Oncogene Proteins c-bcl-2; Receptor, Notch1; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2017 |
Dihydromyricetin protects against lipopolysaccharide‑induced cardiomyocyte injury through the toll‑like receptor‑4/nuclear factor‑κB pathway.
Topics: Animals; Cardiotonic Agents; Cell Line; Cell Survival; Flavonols; Gene Expression Regulation; Inflammation; Inflammation Mediators; Lipopolysaccharides; Myocytes, Cardiac; NF-kappa B; Rats; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4 | 2017 |
Inhibition of human lung cancer proliferation through targeting stromal fibroblasts by dihydromyricetin.
Topics: Antineoplastic Agents; Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Flavonols; Humans; Lung Neoplasms; MAP Kinase Signaling System; Platelet-Derived Growth Factor; Receptors, Platelet-Derived Growth Factor; Stromal Cells | 2017 |
Dihydromyricetin exerts a rapid antidepressant-like effect in association with enhancement of BDNF expression and inhibition of neuroinflammation.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depressive Disorder; Disease Models, Animal; Flavonols; Glycogen Synthase Kinase 3 beta; Hindlimb Suspension; Hippocampus; Locomotion; Male; Mice; Mice, Inbred C57BL; Stress, Psychological; Swimming | 2018 |
Molecular inhibitory mechanism of dihydromyricetin on mushroom tyrosinase.
Topics: Agaricales; Antioxidants; Enzyme Activation; Enzyme Inhibitors; Flavonols; Ligands; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Monophenol Monooxygenase; Quantitative Structure-Activity Relationship; Substrate Specificity | 2018 |
Dihydromyricetin prevents monocrotaline-induced pulmonary arterial hypertension in rats.
Topics: Animals; Disease Models, Animal; Flavonols; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor; Vascular Remodeling | 2017 |
Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down-regulation of phosphorylation of PPARγ in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adiponectin; Anilides; Animals; Cell Survival; Dexamethasone; Down-Regulation; Fibroblast Growth Factors; Flavonoids; Flavonols; Glucose; Insulin Resistance; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Phosphoserine; PPAR gamma | 2018 |
Dihydromyricetin inhibits NLRP3 inflammasome-dependent pyroptosis by activating the Nrf2 signaling pathway in vascular endothelial cells.
Topics: Anti-Inflammatory Agents; Antioxidants; Caspase 1; Flavonols; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammasomes; Interleukin-1beta; L-Lactate Dehydrogenase; Mitochondria; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Palmitic Acid; Primary Cell Culture; Pyroptosis; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction | 2018 |
Dihydromyricetin sensitizes human acute myeloid leukemia cells to retinoic acid-induced myeloid differentiation by activating STAT1.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Drug Synergism; Flavonols; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; MAP Kinase Signaling System; Oncogene Proteins, Fusion; Proteolysis; Signal Transduction; STAT1 Transcription Factor; Tretinoin | 2018 |
Antibacterial Effect of 2R,3R-dihydromyricetin on the Cellular Functions of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Flavonols; Malate Dehydrogenase; Oxidation-Reduction; Proline; Staphylococcus aureus; Succinate Dehydrogenase | 2018 |
Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology.
Topics: Ampelopsis; Drugs, Chinese Herbal; Flavonols; Molecular Structure; Plant Leaves; Solvents; Temperature; Time Factors | 2017 |
Dietary Factors Modulate Colonic Tumorigenesis Through the Interaction of Gut Microbiota and Host Chloride Channels.
Topics: Animals; Bacterial Adhesion; Bile Acids and Salts; Butyrates; Chloride Channels; Colorectal Neoplasms; Cystic Fibrosis Transmembrane Conductance Regulator; Diet; Flavonols; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred BALB C | 2018 |
Dihydromyricetin improves type 2 diabetes-induced cognitive impairment via suppressing oxidative stress and enhancing brain-derived neurotrophic factor-mediated neuroprotection in mice.
Topics: Ampelopsis; Animals; Blood Glucose; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Flavonols; Maze Learning; Mice; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Phytotherapy; Plant Extracts | 2018 |
The Discovery of Antibacterial Natural Compound Based on Peptide Deformylase.
Topics: Amidohydrolases; Anti-Bacterial Agents; Drug Discovery; Flavonols; Humans; Staphylococcus aureus | 2018 |
Dihydromyricetin ameliorates foam cell formation via LXRα-ABCA1/ABCG1-dependent cholesterol efflux in macrophages.
Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; Cholesterol; Dose-Response Relationship, Drug; Flavonols; Foam Cells; Humans; Liver X Receptors; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; THP-1 Cells | 2018 |
Dihydromyricetin relieves rheumatoid arthritis symptoms and suppresses expression of pro-inflammatory cytokines via the activation of Nrf2 pathway in rheumatoid arthritis model.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Flavonols; Freund's Adjuvant; Heme Oxygenase (Decyclizing); Liver; Male; Malondialdehyde; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Interactions of Dihydromyricetin, a Flavonoid from Vine Tea (Ampelopsis grossedentata) with Gut Microbiota.
Topics: Ampelopsis; Animals; Feces; Flavonols; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; RNA, Ribosomal, 16S; Teas, Herbal | 2018 |
Inhibitory Effect of 2R,3R-Dihydromyricetin on Biofilm Formation by Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Biofilms; Flavonols; Food Contamination; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Stainless Steel; Staphylococcus aureus | 2018 |
Dihydromyricetin inhibits microglial activation and neuroinflammation by suppressing NLRP3 inflammasome activation in APP/PS1 transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Brain; Cell Line, Transformed; Cognition Disorders; Cytokines; Disease Models, Animal; Encephalitis; Flavonols; Gene Expression Regulation; Humans; Inflammasomes; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Mutation; NLR Family, Pyrin Domain-Containing 3 Protein; Presenilin-1; RNA, Messenger; Time Factors | 2018 |
[Determination of 8 components in healthy food for anti-hangover and hepatoprotection by high performance liquid chromatography].
Topics: Catechin; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Flavonols; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Sensitivity and Specificity | 2017 |
[Flavonoids from leaves of Psidum littorale].
Topics: Flavonoids; Flavonols; Glycosides; Kaempferols; Plant Leaves; Psidium; Quercetin | 2016 |
[The effects of dihydromyricetin on cognitive dysfunction in type 2 diabetes mice].
Topics: Animals; Blood Glucose; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Flavonols; Hippocampus; Learning; Memory; Mice; Mice, Inbred C57BL | 2017 |
Uptake and Transport Mechanism of Dihydromyricetin Across Human Intestinal Caco-2 Cells.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Availability; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Flavonols; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Neoplasm Proteins | 2018 |
Dihydromyricetin Inhibits Lead-Induced Cognitive Impairments and Inflammation by the Adenosine 5'-Monophosphate-Activated Protein Kinase Pathway in Mice.
Topics: AMP-Activated Protein Kinase Kinases; Ampelopsis; Animals; Apoptosis; Brain; Cognitive Dysfunction; Cytokines; Flavonols; Humans; Inflammation; Lead; Mice; NF-kappa B; Phosphorylation; Plant Extracts; Protein Kinases; Toll-Like Receptor 4 | 2018 |
Dihydromyricetin improves vascular hyporesponsiveness in experimental sepsis via attenuating the over-excited MaxiK and K
Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Flavonols; KATP Channels; Large-Conductance Calcium-Activated Potassium Channels; Lipopolysaccharides; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis; Vasoconstriction | 2018 |
Astragalin and dihydromyricetin as adjuncts to histidine‑tryptophan‑ketoglutarate cardioplegia enhances protection during cardioplegic arrest.
Topics: Animals; Apoptosis; Biomarkers; Cardioplegic Solutions; Cardiotonic Agents; Cytokines; Disease Models, Animal; Flavonols; Glucose; Heart Arrest; Heart Arrest, Induced; Hemodynamics; Inflammation Mediators; Kaempferols; Male; Mannitol; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Potassium Chloride; Procaine; Rats; Recovery of Function; Ventricular Function | 2018 |
Dihydromyricetin inhibits caerulin-induced TRAF3-p38 signaling activation and acute pancreatitis response.
Topics: Acute Disease; Animals; Cell Death; Cell Survival; Cells, Cultured; Ceruletide; Cytokines; Flavonols; Macrophages; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Pancreatitis; Signal Transduction; TNF Receptor-Associated Factor 3 | 2018 |
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Topics: Animals; Bone Resorption; Flavonols; Lipopolysaccharides; Male; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Osteogenesis; Oxidative Stress; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2018 |
Dihydromyricetin Attenuates Dexamethasone-Induced Muscle Atrophy by Improving Mitochondrial Function via the PGC-1α Pathway.
Topics: Animals; ATP Synthetase Complexes; Dexamethasone; DNA, Mitochondrial; Flavonols; GTP Phosphohydrolases; Male; Membrane Potential, Mitochondrial; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Muscular Atrophy; Myoblasts; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Carbonylation; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Signal Transduction; Transcription Factors; Voltage-Dependent Anion Channel 1 | 2018 |
Combination of dihydromyricetin and ondansetron strengthens antiproliferative efficiency of adriamycin in K562/ADR through downregulation of SORCIN: A new strategy of inhibiting P-glycoprotein.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Calcium-Binding Proteins; Cell Proliferation; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonols; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Leukemia; Ondansetron; Proto-Oncogene Proteins c-akt; Signal Transduction | 2019 |
Dihydromyricetin from ampelopsis grossedentata protects against vascular neointimal formation via induction of TR3.
Topics: Ampelopsis; Animals; Carotid Arteries; Carotid Stenosis; Cell Line; Cell Proliferation; Disease Models, Animal; Flavonols; Humans; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Nuclear Receptor Subfamily 4, Group A, Member 1; Rats | 2018 |
Dihydromyricetin as a Functional Additive to Enhance Antioxidant Capacity and Inhibit the Formation of Thermally Induced Food Toxicants in a Cookie Model.
Topics: Antioxidants; Cooking; Drug Synergism; Flavonoids; Flavonols; Food; Food Analysis; Humans; Oxidation-Reduction | 2018 |
Dihydromyricetin Attenuates Myocardial Hypertrophy Induced by Transverse Aortic Constriction via Oxidative Stress Inhibition and SIRT3 Pathway Enhancement.
Topics: Animals; Antioxidants; Cardiomegaly; Flavonols; Male; Mice; Mice, Inbred C57BL; Myocardium; Oxidative Stress; Signal Transduction; Sirtuin 3; Ventricular Outflow Obstruction | 2018 |
Improvement of glucocorticoid-impaired thymus function by dihydromyricetin via up-regulation of PPARγ-associated fatty acid metabolism.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Drug Therapy, Combination; Fatty Acids; Flavonols; Glucocorticoids; Hypersensitivity, Delayed; Mice; PPAR gamma; Thymus Gland; Up-Regulation | 2018 |
Effects of dihydromyricetin on ARPE-19 cell migration through regulating matrix metalloproteinase-2 expression.
Topics: Cell Movement; Cells, Cultured; Epithelial Cells; Flavonols; Humans; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Retina; Vitreoretinopathy, Proliferative | 2018 |
SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Chondrocytes; Female; Flavonols; Homeostasis; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mitochondria; Osteoarthritis; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 3 | 2018 |
Protective role of Dihydromyricetin in Alzheimer's disease rat model associated with activating AMPK/SIRT1 signaling pathway.
Topics: Alzheimer Disease; AMP-Activated Protein Kinases; Amyloid beta-Peptides; Animals; Apoptosis; Cognition; Cytokines; Disease Models, Animal; Flavonols; Gene Expression Regulation; Hippocampus; Injections, Intraperitoneal; Injections, Intraventricular; Male; Maze Learning; Memory; Neurons; Nootropic Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Stereotaxic Techniques | 2019 |
Nanoencapsulation of the flavonoid dihydromyricetin protects against the genotoxicity and cytotoxicity induced by cationic nanocapsules.
Topics: Acrylic Resins; Antioxidants; Cations; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Flavonoids; Flavonols; Humans; Leukocytes, Mononuclear; MCF-7 Cells; Nanocapsules; Nanotechnology; Particle Size; Polymers; Proteins | 2019 |
Semaphoring 4D is required for the induction of antioxidant stress and anti-inflammatory effects of dihydromyricetin in colon cancer.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Flavonols; Humans; Male; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Oxidative Stress; Semaphorins | 2019 |
Protective effect of dihydromyricetin revents fatty liver through nuclear factor‑κB/p53/B‑cell lymphoma 2‑associated X protein signaling pathways in a rat model.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; bcl-2-Associated X Protein; Disease Models, Animal; Fatty Liver; Flavonols; Gene Expression Regulation; Humans; Inflammation; Liver; NF-kappa B; Oxidative Stress; Rats; Signal Transduction; Superoxide Dismutase; Tumor Suppressor Protein p53 | 2019 |
Protective effect of dihydromyricetin on hyperthermia-induced apoptosis in human myelomonocytic lymphoma cells.
Topics: Apoptosis; Caspases; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Fever; Flavonols; Humans; Lymphoma; Membrane Potential, Mitochondrial; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Signal Transduction; U937 Cells | 2019 |
Dihydromyricetin attenuates hypertrophic scar formation by targeting activin receptor-like kinase 5.
Topics: Adolescent; Adult; Animals; Biocatalysis; Cell Proliferation; Cicatrix, Hypertrophic; Female; Fibroblasts; Flavonols; Humans; Male; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Targeted Therapy; Phosphorylation; Protein Conformation; Receptor, Transforming Growth Factor-beta Type I; Smad2 Protein; Smad3 Protein; Young Adult | 2019 |
MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells.
Topics: Animals; Cell Line; Disease Models, Animal; Doxorubicin; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Flavonols; Glucuronidase; Humans; Kidney; Kidney Diseases; Kidney Tubules; Klotho Proteins; Mice; MicroRNAs; Signal Transduction; Transforming Growth Factor beta1; Ureteral Obstruction | 2019 |
Dihydromyricetin ameliorates memory impairment induced by acute sleep deprivation.
Topics: Acute Disease; Animals; Flavonols; Maze Learning; Memory Disorders; Mice; Neuronal Plasticity; Oxidative Stress; Sleep Deprivation | 2019 |
Dihydromyricetin Alleviates Sepsis-Induced Acute Lung Injury through Inhibiting NLRP3 Inflammasome-Dependent Pyroptosis in Mice Model.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonols; Inflammasomes; Male; Mice; Mice, Inbred BALB C; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Sepsis | 2019 |
Dihydromyricetin Inhibits α-Synuclein Aggregation, Disrupts Preformed Fibrils, and Protects Neuronal Cells in Culture against Amyloid-Induced Cytotoxicity.
Topics: alpha-Synuclein; Ampelopsis; Amyloid beta-Peptides; Animals; Apoptosis; Drugs, Chinese Herbal; Flavonols; Humans; Hydrophobic and Hydrophilic Interactions; Neurons; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Protein Aggregates; Rats | 2019 |
Synergy between dihydromyricetin intervention and irinotecan chemotherapy delays the progression of colon cancer in mouse models.
Topics: Animals; Chloride Channels; Colonic Neoplasms; Disease Models, Animal; Disease Progression; Drug Synergism; Flavonols; Humans; Irinotecan; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins | 2019 |
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Topics: Acetaminophen; Animals; Cell Death; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Flavonols; Glutathione; Hepatocytes; Homeostasis; Lipid Metabolism; Lipids; Liver; Liver Regeneration; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Signal Transduction | 2019 |
Solid Self-Emulsifying Delivery System (S-SEDS) of Dihydromyricetin: A New Way for Preparing Functional Food.
Topics: Antioxidants; Biological Availability; Drug Delivery Systems; Emulsions; Flavonols; Food Handling; Food Technology; Functional Food; Humans; Powders; Silicon Dioxide; Solubility; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2019 |
Dihydromyricetin affect the pharmacokinetics of triptolide in rats.
Topics: Animals; Area Under Curve; Chromatography, Liquid; Diterpenes; Epoxy Compounds; Flavonols; Male; Phenanthrenes; Rats; Tandem Mass Spectrometry | 2020 |
Dihydromyricetin protects HUVECs of oxidative damage induced by sodium nitroprusside through activating PI3K/Akt/FoxO3a signalling pathway.
Topics: Cell Death; Chromones; Cytoprotection; Flavonols; Forkhead Box Protein O3; Human Umbilical Vein Endothelial Cells; Humans; Models, Biological; Morpholines; Nitroprusside; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Protective Agents; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction | 2019 |
Dihydromyricetin Ameliorates Cardiac Ischemia/Reperfusion Injury through Sirt3 Activation.
Topics: Animals; Cardiotonic Agents; Cells, Cultured; DNA-Binding Proteins; Flavonols; High Mobility Group Proteins; Male; Mice; Mitochondria; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxygen; Sirtuin 3 | 2019 |
Preparation of a nanoscale dihydromyricetin-phospholipid complex to improve the bioavailability: in vitro and in vivo evaluations.
Topics: Animals; Biological Availability; Calorimetry, Differential Scanning; Diabetes Mellitus, Type 2; Flavonols; Male; Microscopy, Electron, Scanning; Particle Size; Phospholipids; Rats; Rats, Sprague-Dawley; Solubility; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2019 |
Irisin vs. Treadmill Exercise in Post Myocardial Infarction Cardiac Rehabilitation in Rats.
Topics: Animals; Cardiac Rehabilitation; Fibronectins; Flavonols; Humans; Male; Myocardial Contraction; Myocardial Infarction; Myocardium; Physical Conditioning, Animal; Rats; Ventricular Remodeling | 2019 |
Antibacterial Activity and Mode of Action of Dihydromyricetin from
Topics: Ampelopsis; Anti-Bacterial Agents; Bacteria; Cell Membrane; Cell Membrane Permeability; Cell Wall; Flavonols; Foodborne Diseases; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Molecular Structure; Oxidative Phosphorylation; Plant Extracts; Plant Leaves; Structure-Activity Relationship | 2019 |
Semi-preparative separation of dihydromyricetin enantiomers by supercritical fluid chromatography and determination of anti-inflammatory activities.
Topics: Animals; Anti-Inflammatory Agents; Chromatography, Supercritical Fluid; Flavonols; Inhibitory Concentration 50; Mice; RAW 264.7 Cells; Rheology; Solvents; Stereoisomerism | 2019 |
Dihydromyricetin inhibited ovalbumin-induced mice allergic responses by suppressing the activation of mast cells.
Topics: Animals; Anti-Allergic Agents; B-Lymphocytes; Female; Flavonols; Food Hypersensitivity; Humans; Immunoglobulin E; Mast Cells; Mice; Mice, Inbred BALB C; Ovalbumin; Passive Cutaneous Anaphylaxis | 2019 |
Inhibitory Effect of a Flavonoid Dihydromyricetin against Aβ40 Amyloidogenesis and Its Associated Cytotoxicity.
Topics: Amyloid beta-Peptides; Amyloidosis; Animals; Cytotoxins; Dose-Response Relationship, Drug; Flavonoids; Flavonols; PC12 Cells; Peptide Fragments; Protein Structure, Secondary; Rats | 2019 |
Dihydromyricetin affects BDNF levels in the nervous system in rats with comorbid diabetic neuropathic pain and depression.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Comorbidity; Depression; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Flavonols; Hippocampus; Humans; Male; Pain Measurement; Rats; Receptor, trkB; Signal Transduction; Streptozocin | 2019 |
Dihydromyricetin promotes autophagy and attenuates renal interstitial fibrosis by regulating miR-155-5p/PTEN signaling in diabetic nephropathy.
Topics: Animals; Autophagy; Cells, Cultured; Diabetic Nephropathies; Disease Models, Animal; Flavonols; MicroRNAs; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Signal Transduction; Transfection | 2020 |
Golgi reassembly and stacking protein 65 downregulation is required for the anti-cancer effect of dihydromyricetin on human ovarian cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Movement; Down-Regulation; Female; Flavonols; Golgi Matrix Proteins; Humans; MAP Kinase Signaling System; Ovarian Neoplasms; Proto-Oncogene Proteins c-bcl-2; RNA Interference; RNA, Small Interfering; Up-Regulation | 2019 |
Regulation of signaling pathways by Ampelopsin (Dihydromyricetin) in different cancers: exploring the highways and byways less travelled.
Topics: Animals; Apoptosis; Flavonoids; Flavonols; Humans; Neoplasms; Signal Transduction | 2019 |
[Effects of dihydromyricetin on the migration and invasion of human gastric cancer MKN45 cells and its mechanism].
Topics: Cadherins; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Flavonols; Gene Expression Regulation; Humans; Neoplasm Invasiveness; Stomach Neoplasms; Vimentin | 2019 |
Hydrogels assembled from ovotransferrin fibrils and xanthan gum as dihydromyricetin delivery vehicles.
Topics: Conalbumin; Drug Compounding; Flavonols; Food Industry; Humans; Hydrogels; Polysaccharides; Polysaccharides, Bacterial | 2020 |
Development and characterization of an inducible Dicer conditional knockout mouse model of Parkinson's disease: validation of the antiparkinsonian effects of a sigma-1 receptor agonist and dihydromyricetin.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; DEAD-box RNA Helicases; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flavonols; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Morpholines; Oxidopamine; Parkinson Disease; Receptors, sigma; Ribonuclease III; Sigma-1 Receptor; Tamoxifen | 2020 |
Dihydromyricetin alleviates doxorubicin-induced cardiotoxicity by inhibiting NLRP3 inflammasome through activation of SIRT1.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Cardiotoxicity; Cell Line; Cell Survival; Doxorubicin; Flavonols; Heart; Inflammasomes; Male; Myocardium; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Sirtuin 1; Ventricular Dysfunction, Left | 2020 |
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts.
Topics: alpha-Synuclein; Animals; Benzofurans; Drugs, Chinese Herbal; Flavonols; HEK293 Cells; Humans; Mice; Molecular Structure; Plant Extracts; Protein Aggregation, Pathological; Synucleinopathies | 2020 |
Dihydromyricetin Prevents Diabetic Cardiomyopathy via miR-34a Suppression by Activating Autophagy.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Proteins; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Down-Regulation; Flavonols; Male; Mice; MicroRNAs; Myocytes, Cardiac; Rats, Wistar; Signal Transduction; Ventricular Function, Left | 2020 |
Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin.
Topics: Age Factors; Animals; Cell Line, Transformed; Diet, High-Fat; Flavonols; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Receptors, LDL; Sirtuin 1 | 2020 |
Annotation of genes involved in high level of dihydromyricetin production in vine tea (Ampelopsis grossedentata) by transcriptome analysis.
Topics: Ampelopsis; China; Flavonoids; Flavonols; Gene Expression; Gene Expression Profiling | 2020 |
[Dihydromyricetin ameliorates chronic social defeat stress induced cognitive and affective disorder in mice].
Topics: Animals; Anxiety; Depression; Disease Models, Animal; Flavonols; Hippocampus; Learning; Memory; Mice; Mice, Inbred C57BL; Mood Disorders; Random Allocation; Sirtuin 1; Stress, Psychological | 2019 |
Dihydromyricetin Protects the Liver via Changes in Lipid Metabolism and Enhanced Ethanol Metabolism.
Topics: Adenylate Kinase; Animals; Dietary Supplements; Enzyme Activation; Ethanol; Fatty Liver, Alcoholic; Flavonols; Hep G2 Cells; Humans; Lipid Metabolism; Liver; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C57BL; Triglycerides | 2020 |
Dihydromyricetin increases endothelial nitric oxide production and inhibits atherosclerosis through microRNA-21 in apolipoprotein E-deficient mice.
Topics: Amidohydrolases; Animals; Apolipoproteins E; Arginine; Atherosclerosis; Enzyme Activation; Flavonols; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipid Metabolism; Lipids; Liver; Male; Mice, Inbred C57BL; MicroRNAs; Nitric Oxide; Nitric Oxide Synthase Type III; Signal Transduction | 2020 |
Influence of Natural Polyphenols on Isolated Yeast Dipodascus magnusii Mitochondria.
Topics: Antioxidants; Catechin; Flavonoids; Flavonols; Microbial Sensitivity Tests; Mitochondria; Oxygen Consumption; Polyphenols; Quercetin; Reactive Oxygen Species; Resveratrol; Saccharomycetales; Stilbenes | 2020 |
Synthesis of Dihydromyricetin Coated Multi-Walled Carbon Nanotubes (MWCNTs) and Antibacterial Activities.
Topics: Anti-Bacterial Agents; Flavonols; Nanotubes, Carbon; Spectroscopy, Fourier Transform Infrared | 2020 |
Dihydromyricetin attenuates Escherichia coli lipopolysaccharide-induced ileum injury in chickens by inhibiting NLRP3 inflammasome and TLR4/NF-κB signalling pathway.
Topics: Animals; Anti-Bacterial Agents; Chickens; Escherichia coli; Escherichia coli Infections; Female; Flavonols; Ileum; Inflammasomes; Lipopolysaccharides; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Poultry Diseases; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Reversal Effect of Dihydromyricetin on Multiple Drug Resistance in SGC7901/5-FU Cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonols; Fluorouracil; Humans; Stomach Neoplasms; Tumor Cells, Cultured | 2020 |
[Effects of dihydromyricetin on high fat diet induced obesity in mice and its mechanism].
Topics: Adipose Tissue, Brown; Animals; Body Weight; Diet, High-Fat; Flavonols; Male; Mice; Mice, Inbred C57BL; Obesity; Random Allocation | 2020 |
Fabrication and characterization of dihydromyricetin encapsulated zein-caseinate nanoparticles and its bioavailability in rat.
Topics: Animals; Biological Availability; Caseins; Chromatography, High Pressure Liquid; Female; Flavonols; Mice; Nanoparticles; Particle Size; Rats; Tandem Mass Spectrometry; Zein | 2020 |
DMY protects the knee joints of rats with collagen-induced arthritis by inhibition of NF-κB signaling and osteoclastic bone resorption.
Topics: Animals; Arthritis, Experimental; Bone Resorption; Cartilage, Articular; Cell Line; Collagen; Flavonols; Knee Joint; Male; NF-kappa B; Osteoblasts; Osteoclasts; RANK Ligand; Rats; Rats, Wistar; Signal Transduction | 2020 |
Feature-Based Molecular Networking Analysis of the Metabolites Produced by
Topics: Bacteria; Camellia sinensis; Catechin; Fermentation; Flavonoids; Flavonols; Food Handling; Food Microbiology; Tea | 2020 |
Ameliorative effects and molecular mechanisms of vine tea on western diet-induced NAFLD.
Topics: AMP-Activated Protein Kinases; Ampelopsis; Animals; Antioxidants; Carnitine O-Palmitoyltransferase; Cytochrome P-450 CYP4A; Diet, High-Fat; Diet, Western; Drugs, Chinese Herbal; Flavonols; Gastrointestinal Microbiome; Hep G2 Cells; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Lipid Metabolism; Liver; Membrane Proteins; Mice, Inbred C57BL; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phytotherapy; PPAR alpha; Teas, Herbal | 2020 |
The Effect of Dihydromyricetin, a Natural Flavonoid, on Morphine-induced Conditioned Place Preference and Physical Dependence in Mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Flavonoids; Flavonols; Locomotion; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone | 2020 |
Novel plant flavonoid electrochemical sensor based on in-situ and controllable double-layered membranes modified electrode.
Topics: Biosensing Techniques; Carbon; Electrochemical Techniques; Electrodes; Flavonoids; Flavonols; Gold; Graphite; Limit of Detection; Metal Nanoparticles; Molecular Imprinting; Plant Extracts; Polymers; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2020 |
Assessment of binding interaction dihydromyricetin and myricetin with bovine lactoferrin and effects on antioxidant activity.
Topics: Antioxidants; Binding Sites; Circular Dichroism; Flavonoids; Flavonols; Lactoferrin; Molecular Docking Simulation; Protein Binding; Serum Albumin, Bovine; Thermodynamics | 2020 |
Flavonoids as BACE1 inhibitors: QSAR modelling, screening and in vitro evaluation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Disaccharides; Flavonoids; Flavonols; Humans; Molecular Docking Simulation; Neurons; Oxidative Stress; Plaque, Amyloid; Protein Conformation; Quantitative Structure-Activity Relationship; Quercetin | 2020 |
Dihydromyricetin improves mitochondrial outcomes in the liver of alcohol-fed mice via the AMPK/Sirt-1/PGC-1α signaling axis.
Topics: Alcoholism; AMP-Activated Protein Kinases; Animals; Ethanol; Flavonols; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Signal Transduction; Sirtuin 1 | 2021 |
The cytoprotective effects of dihydromyricetin and associated metabolic pathway changes on deoxynivalenol treated IPEC-J2 cells.
Topics: Animals; Cell Line; Cell Survival; Cytoprotection; Epithelial Cells; Flavonols; Swine; Trichothecenes | 2021 |
UVB photoprotective capacity of hydrogels containing dihydromyricetin nanocapsules to UV-induced DNA damage.
Topics: DNA Damage; Flavonols; Hydrogels; Nanocapsules; Skin; Ultraviolet Rays | 2021 |
Fabrication and characterization of novel edible Pickering emulsion gels stabilized by dihydromyricetin.
Topics: Emulsions; Flavonols; Gels; Osmolar Concentration | 2021 |
Anti-HSV-1 effect of dihydromyricetin from Ampelopsis grossedentata via the TLR9-dependent anti-inflammatory pathway.
Topics: Ampelopsis; Animals; Anti-Inflammatory Agents; Chlorocebus aethiops; Flavonols; Herpesvirus 1, Human; Humans; Toll-Like Receptor 9; Vero Cells | 2020 |
Dihydromyricetin ameliorates chronic liver injury by reducing pyroptosis.
Topics: Animals; Flavonols; Liver; Mice; Mice, Inbred NOD; Pyroptosis | 2020 |
Dihydromyricetin promotes longevity and activates the transcription factors FOXO and AOP in
Topics: Aging; Animals; Drosophila melanogaster; Drosophila Proteins; Eye Proteins; Flavonols; Forkhead Transcription Factors; Longevity; Repressor Proteins | 2020 |
Mechanism and antibacterial activity of vine tea extract and dihydromyricetin against Staphylococcus aureus.
Topics: Alkaline Phosphatase; Ampelopsis; Anti-Bacterial Agents; Bacterial Proteins; beta-Galactosidase; Cell Membrane; Flavonols; Food Preservation; Gene Expression Regulation, Bacterial; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Plant Extracts; Staphylococcus aureus | 2020 |
Physicochemical properties of dihydromyricetin and the effects of ascorbic acid on its stability and bioavailability.
Topics: Animals; Ascorbic Acid; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Female; Flavonols; Kinetics; Rats; Rats, Sprague-Dawley; Solubility | 2021 |
Dihydromyricetin reverses MRP2-induced multidrug resistance by preventing NF-κB-Nrf2 signaling in colorectal cancer cell.
Topics: Animals; Apoptosis; Colonic Neoplasms; Colorectal Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonols; HCT116 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; NF-E2-Related Factor 2; NF-kappa B; Oxaliplatin; Signal Transduction; Vincristine | 2021 |
[Dihydromyricetin inhibits proliferation and migration of gastric cancer cells through regulating Akt/STAT3 signaling pathways and HMGB1 expression].
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Flavonols; HMGB1 Protein; Humans; Proto-Oncogene Proteins c-akt; STAT3 Transcription Factor; Stomach Neoplasms | 2021 |
Dihydromyricetin incorporated active films based on konjac glucomannan and gellan gum.
Topics: Anti-Bacterial Agents; Antioxidants; Biocompatible Materials; Flavonols; Food Packaging; Hydrogen Bonding; Mannans; Microscopy, Electron, Scanning; Permeability; Polysaccharides, Bacterial; Spectroscopy, Fourier Transform Infrared; Steam; Tensile Strength; Ultraviolet Rays; Water | 2021 |
Does dihydromyricetin impact on alcohol metabolism.
Topics: Alcohol Dehydrogenase; Animals; Antioxidants; Cells, Cultured; Cytochrome P-450 CYP2E1; Ethanol; Flavonols; Hepatocytes; Inactivation, Metabolic; Liver; Male; Nitrosative Stress; Oxidative Stress; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species | 2020 |
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
Topics: Animals; Apoptosis; Cattle; Cell Survival; Dynamins; Epithelial Cells; Female; Flavonols; Heat-Shock Response; Mitochondria; Mitochondrial Dynamics; Oxidative Stress; Protective Agents | 2021 |
Self-Assembled Micelles Improve the Oral Bioavailability of Dihydromyricetin and Anti-Acute Alcoholism Activity.
Topics: Alcoholic Intoxication; Animals; Area Under Curve; Biological Availability; Central Nervous System Depressants; Ethanol; Excipients; Flavonols; Gastric Mucosa; Hepatitis, Alcoholic; Male; Mice; Mice, Inbred C57BL; Micelles; Nanoparticles; Postural Balance; Rats; Rats, Sprague-Dawley; Surface-Active Agents | 2021 |
Dihydromyricetin inhibits oxidative stress and apoptosis in oxygen and glucose deprivation/reoxygenation‑induced HT22 cells by activating the Nrf2/HO‑1 pathway.
Topics: Animals; Antioxidants; Apoptosis; Cell Hypoxia; Cell Line; Flavonols; Glucose; Glutathione; Heme Oxygenase-1; Malondialdehyde; Mice; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction | 2021 |
Multi-scale stabilization mechanism of pickering emulsion gels based on dihydromyricetin/high-amylose corn starch composite particles.
Topics: Amylose; Emulsions; Flavonols; Gels; Osmolar Concentration; Starch; Viscosity | 2021 |
A Novel Dual Drug Approach That Combines Ivermectin and Dihydromyricetin (DHM) to Reduce Alcohol Drinking and Preference in Mice.
Topics: Alcohol Drinking; Alcoholism; Animals; Drug Therapy, Combination; Female; Flavonols; Ivermectin; Male; Mice | 2021 |
Dihydromyricetin Imbues Antiadipogenic Effects on 3T3-L1 Cells via Direct Interactions with 78-kDa Glucose-Regulated Protein.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Endoplasmic Reticulum Chaperone BiP; Flavonols; Glucose; Mice; Molecular Docking Simulation | 2021 |
Effect of dihydromyricetin on hepatic encephalopathy associated with acute hepatic failure in mice.
Topics: Animals; Female; Flavonols; Hepatic Encephalopathy; Hippocampus; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Treatment Outcome | 2021 |
Dihydromyricetin attenuates D-galactose-induced brain aging of mice via inhibiting oxidative stress and neuroinflammation.
Topics: Aging; Animals; Antioxidants; Brain; Cellular Senescence; Flavonols; Galactose; Hippocampus; Inflammation; Malondialdehyde; Mice; Neuroprotective Agents; Oxidative Stress; Spatial Learning; Spatial Memory | 2021 |
Dihydromyricetin promotes apoptosis, suppresses proliferation and tumor necrosis factor-α-mediated nuclear factor kappa-B activation in nasopharyngeal carcinoma CNE-2 cell.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Flavonols; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; NF-kappa B; Tumor Necrosis Factor-alpha | 2021 |
A Drug-Drug Cocrystal of Dihydromyricetin and Pentoxifylline.
Topics: Crystallization; Crystallography, X-Ray; Flavonols; Pentoxifylline; Solubility; X-Ray Diffraction | 2022 |
Dietary dihydromyricetin supplementation enhances antioxidant capacity and improves lipid metabolism in finishing pigs.
Topics: Animal Feed; Animals; Antioxidants; Catalase; Dietary Supplements; Flavonols; Lipid Metabolism; Male; Malondialdehyde; Muscle, Skeletal; Sus scrofa; Swine | 2021 |
IgE-Induced Mast Cell Activation Is Suppressed by Dihydromyricetin through the Inhibition of NF-κB Signaling Pathway.
Topics: Cell Degranulation; Cell Line; Flavonols; Humans; Immunoglobulin E; Mast Cells; NF-kappa B; Signal Transduction | 2021 |
Anticancer effects of dihydromyricetin on the proliferation, migration, apoptosis and in vivo tumorigenicity of human hepatocellular carcinoma Hep3B cells.
Topics: Animals; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Flavonols; Humans; In Vitro Techniques; Liver Neoplasms; Mice; Mice, Nude; Random Allocation | 2021 |
Dihydromyricetin suppresses cell metastasis in human osteosarcoma through SP-1- and NF-κB-modulated urokinase plasminogen activator inhibition.
Topics: Bone Neoplasms; Cell Line, Tumor; Cell Movement; Flavonols; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Osteosarcoma; Sp1 Transcription Factor; Urokinase-Type Plasminogen Activator | 2021 |
Dihydromyricetin improves DSS-induced colitis in mice via modulation of fecal-bacteria-related bile acid metabolism.
Topics: Animals; Anti-Inflammatory Agents; Bacteria; Bile Acids and Salts; Caco-2 Cells; Colitis; Colon; Dextran Sulfate; Dysbiosis; Fecal Microbiota Transplantation; Feces; Flavonols; Gastrointestinal Microbiome; Humans; Interleukin-1beta; Male; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Tumor Necrosis Factor-alpha | 2021 |
Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CL
Topics: 3C Viral Proteases; Ampelopsis; Antiviral Agents; Binding Sites; Cysteine; Flavonoids; Flavonols; Mass Spectrometry; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Plant Extracts; Protease Inhibitors; Protein Binding; Protein Conformation; SARS-CoV-2 | 2021 |
Exploring the genes involved in biosynthesis of dihydroquercetin and dihydromyricetin in Ampelopsis grossedentata.
Topics: Ampelopsis; Biosynthetic Pathways; Cluster Analysis; Flavonoids; Flavonols; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Ontology; Genes, Plant; Molecular Sequence Annotation; Quercetin; RNA, Messenger; Transcriptome | 2021 |
Effect of dihydromyricetin on SARS-CoV-2 viral replication and pulmonary inflammation and fibrosis.
Topics: Animals; Antiviral Agents; Coronavirus 3C Proteases; COVID-19; Fibrosis; Flavonols; Humans; Lung; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Protease Inhibitors; SARS-CoV-2; Virus Replication | 2021 |
The role of miR-199b-3p in regulating Nrf2 pathway by dihydromyricetin to alleviate septic acute kidney injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Disease Models, Animal; Flavonols; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; MicroRNAs; NF-E2-Related Factor 2; Sepsis | 2021 |
Topics: Ampelopsis; Animals; Antiviral Agents; Flavonols; Herpesvirus 1, Suid | 2022 |
Dihydromyricetin ameliorates vascular calcification in chronic kidney disease by targeting AKT signaling.
Topics: Animals; Aorta; Aortic Diseases; Cells, Cultured; Disease Models, Animal; Flavonols; Humans; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteogenesis; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Signal Transduction; Vascular Calcification | 2021 |
Dihydromyricetin Ameliorates Inflammation-Induced Insulin Resistance via Phospholipase C-CaMKK-AMPK Signal Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Diabetes Mellitus, Type 2; Flavonols; Inflammation; Insulin Resistance; Male; Mice, Inbred C57BL; Signal Transduction | 2021 |
Dihydromyricetin resists inflammation-induced muscle atrophy via ryanodine receptor-CaMKK-AMPK signal pathway.
Topics: AMP-Activated Protein Kinases; Animals; Biomarkers; Body Composition; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cell Line; Diet, High-Fat; Disease Models, Animal; Disease Susceptibility; Flavonols; Glucose; Inflammation; Male; Mice; Molecular Imaging; Muscle, Skeletal; Muscular Atrophy; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Tumor Necrosis Factor-alpha | 2021 |
Fabrication of food-grade Pickering high internal phase emulsions (HIPEs) stabilized by a dihydromyricetin and lysozyme mixture.
Topics: Emulsions; Flavonols; Food; Muramidase; Particle Size | 2022 |
Effect of dietary dihydromyricetin supplementation on lipid metabolism, antioxidant capacity and skeletal muscle fiber type transformation in mice.
Topics: Animal Feed; Animals; Antioxidants; Dietary Supplements; Flavonols; Lipid Metabolism; Male; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; RNA, Messenger; Superoxide Dismutase | 2022 |
Dihydromyricetin alleviates cerebral ischemia-reperfusion injury by attenuating apoptosis and astrogliosis in peri-infarct cortex.
Topics: Animals; Apoptosis; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Flavonols; Gliosis; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury | 2022 |
Effect of the natural flavonoids myricetin and dihydromyricetin on the wound healing process in vitro.
Topics: Flavonoids; Flavonols; Lipopolysaccharides; Matrix Metalloproteinase 1; Wound Healing | 2021 |
Dihydromyricetin Improves Cognitive Impairments in d-Galactose-Induced Aging Mice through Regulating Oxidative Stress and Inhibition of Acetylcholinesterase.
Topics: Acetylcholinesterase; Aging; Animals; Cognitive Dysfunction; Flavonols; Galactose; Mice; Neurodegenerative Diseases; Oxidative Stress | 2022 |
Social isolation induces neuroinflammation and microglia overactivation, while dihydromyricetin prevents and improves them.
Topics: Animals; Anxiety; Flavonols; Inflammation Mediators; Male; Maze Learning; Mice; Mice, Inbred C57BL; Microglia; Social Isolation | 2022 |
Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium.
Topics: Animals; Chromatography, Liquid; Culture Media; Eagles; Flavonols; Tandem Mass Spectrometry | 2022 |
Dihydromyricetin alleviates Escherichia coli lipopolysaccharide-induced hepatic injury in chickens by inhibiting the NLRP3 inflammasome.
Topics: Animals; Chickens; Escherichia coli; Escherichia coli Infections; Flavonols; Inflammasomes; Lipopolysaccharides; Liver; NLR Family, Pyrin Domain-Containing 3 Protein | 2022 |
Dihydromyricetin ameliorates oxygen‑glucose deprivation and re‑oxygenation‑induced injury in HT22 cells by activating the Wnt/β‑catenin signaling pathway.
Topics: Apoptosis; Cell Survival; Flavonols; Glucose; Oxidative Stress; Oxygen; Wnt Signaling Pathway | 2022 |
Dihydromyricetin improves LPS-induced sickness and depressive-like behaviors in mice by inhibiting the TLR4/Akt/HIF1a/NLRP3 pathway.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Flavonols; Hypoxia-Inducible Factor 1, alpha Subunit; Illness Behavior; Lipopolysaccharides; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Proto-Oncogene Proteins c-akt; Signal Transduction; Toll-Like Receptor 4 | 2022 |
Dihydromyricetin inhibits cancer cell migration and matrix metalloproteinases-2 expression in human nasopharyngeal carcinoma through extracellular signal-regulated kinase signaling pathway.
Topics: Cell Line, Tumor; Cell Movement; Extracellular Signal-Regulated MAP Kinases; Flavonols; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Signal Transduction | 2022 |
Investigation on the interaction between myricetin and dihydromyricetin with trypsin, α-chymotrypsin, lysozyme by spectroscopy and molecular docking methods.
Topics: Binding Sites; Chymotrypsin; Flavonoids; Flavonols; Molecular Docking Simulation; Muramidase; Protein Binding; Spectrometry, Fluorescence; Thermodynamics; Trypsin | 2022 |
Dihydromyricetin Protects Against Ethanol-Induced Toxicity in SH-SY5Y Cell Line: Role of GABA
Topics: Butyrates; Cell Line, Tumor; Ethanol; Flavonols; Humans; Receptors, GABA-A | 2022 |
Dihydromyricetin improves social isolation-induced cognitive impairments and astrocytic changes in mice.
Topics: Animals; Astrocytes; Cognitive Dysfunction; Flavonols; Hippocampus; Mice; Social Isolation | 2022 |
Separation of principal component dihydromyricetin from Ampelopsis grossedentata by high-speed counter-current chromatography and its interaction with corn starch.
Topics: Ampelopsis; Countercurrent Distribution; Flavonols; Spectroscopy, Fourier Transform Infrared; Starch; Water; Zea mays | 2022 |
A designed self-microemulsion delivery system for dihydromyricetin and its dietary intervention effect on high-fat-diet fed mice.
Topics: Animals; Diet, High-Fat; Flavonols; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease | 2022 |
Dihydromyricetin Improves High-Fat Diet-Induced Hyperglycemia through ILC3 Activation via a SIRT3-Dependent Mechanism.
Topics: Animals; Diet, High-Fat; Flavonols; Hyperglycemia; Immunity, Innate; Insulin Resistance; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Sirtuin 3 | 2022 |
[Dihydromyricetin improves cardiac insufficiency by inhibiting HMGB1 in diabetic rats].
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Flavonols; Heart Failure; HMGB1 Protein; Male; Metformin; NF-kappa B; Rats; Rats, Sprague-Dawley | 2022 |
Dihydromyricetin protects against high glucose-induced endothelial dysfunction: Role of HIF-1α/ROR2/NF-κB.
Topics: Acetylcholine; Animals; bcl-2-Associated X Protein; Caspase 3; Female; Flavonols; Glucose; Glucose Transporter Type 1; Hyperglycemia; Hypoxia-Inducible Factor 1, alpha Subunit; NF-kappa B; Rats; Receptor Tyrosine Kinase-like Orphan Receptors; Tumor Necrosis Factor-alpha; Vascular Diseases | 2022 |
A poloxamer/hyaluronic acid/chitosan-based thermosensitive hydrogel that releases dihydromyricetin to promote wound healing.
Topics: Antioxidants; Chitosan; Flavonols; Humans; Hyaluronic Acid; Hydrogels; Poloxamer; Wound Healing | 2022 |
Effects of dietary dihydromyricetin supplementation on intestinal barrier and humoral immunity in growing-finishing pigs.
Topics: Animal Feed; Animals; Diet; Dietary Supplements; Flavonols; Immunity, Humoral; Interleukin-10; Intestines; RNA, Messenger; Swine | 2022 |
Self-assembly CuO-loaded nanocomposite involving functionalized DNA with dihydromyricetin for water-based efficient and controllable antibacterial action.
Topics: Anti-Bacterial Agents; Copper; DNA; Escherichia coli; Flavonols; Nanocomposites; Staphylococcus aureus; Water | 2022 |
Comprehensive analysis of dihydromyricetin metabolites in rats using ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Flavonols; Mass Spectrometry; Rats; Rats, Sprague-Dawley | 2022 |
Pro-Apoptotic Effect of Zeolitic Imidazolate Framework-8 (ZIF-8)-Loaded Dihydromyricetin on HepG2 Cells.
Topics: Flavonols; Hep G2 Cells; Humans; Reactive Oxygen Species; Renal Dialysis; Zeolites | 2022 |
Dihydromyricetin Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting SPHK1/mTOR Signaling and Targeting Ferroptosis.
Topics: Animals; Coenzyme A; Ferroptosis; Flavonols; Glucose; Infarction, Middle Cerebral Artery; Iron; Ligases; Lipids; Mammals; Oxygen; Phosphatidylethanolamine Binding Protein; Phospholipid Hydroperoxide Glutathione Peroxidase; Phosphotransferases (Alcohol Group Acceptor); Rats; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; TOR Serine-Threonine Kinases; Water | 2022 |
Dihydromyricetin alters myosin heavy chain expression
Topics: AMP-Activated Protein Kinases; Animals; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Flavonols; Lactate Dehydrogenases; Malate Dehydrogenase; Muscle Fibers, Skeletal; Muscle, Skeletal; Myosin Heavy Chains; Nuclear Respiratory Factor 1; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Peroxisome Proliferator-Activated Receptors; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Succinate Dehydrogenase; Swine | 2022 |
Dihydromyricetin alleviates methotrexate-induced hepatotoxicity via suppressing the TLR4/NF-κB pathway and NLRP3 inflammasome/caspase 1 axis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 1; Chemical and Drug Induced Liver Injury; Cytokines; Flavonols; Glutathione; Inflammasomes; Interleukin-18; Interleukin-1beta; Malondialdehyde; Methotrexate; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Rats; Toll-Like Receptor 4 | 2022 |
Dihydromyricetin Enhances Exercise-Induced GLP-1 Elevation through Stimulating cAMP and Inhibiting DPP-4.
Topics: Animals; Fatty Acids, Volatile; Flavonols; Glucagon-Like Peptide 1; Mice | 2022 |
Dihydromyricetin Inhibited Migration and Invasion by Reducing S100A4 Expression through ERK1/2/β-Catenin Pathway in Human Cervical Cancer Cell Lines.
Topics: beta Catenin; Cell Movement; Female; Flavonols; HeLa Cells; Humans; MAP Kinase Signaling System; S100 Calcium-Binding Protein A4; Uterine Cervical Neoplasms | 2022 |
Identification of Hydroxylation Enzymes and the Metabolic Analysis of Dihydromyricetin Synthesis in
Topics: Ampelopsis; Flavonols; Hydroxylation; Plant Leaves | 2022 |
Dihydromyricetin Attenuates High-Intensity Exercise-Induced Intestinal Barrier Dysfunction Associated with the Modulation of the Phenotype of Intestinal Intraepithelial Lymphocytes.
Topics: Animals; Flavonols; Gastrointestinal Diseases; Intestinal Diseases; Intestinal Mucosa; Intraepithelial Lymphocytes; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Phenotype; Physical Conditioning, Animal | 2022 |
Dihydromyricetin suppresses inflammatory injury in microglial cells to improve neurological behaviors of Alzheimer's disease mice via the TLR4/MD2 signal.
Topics: Alzheimer Disease; Animals; Flavonols; Mice; Mice, Inbred C57BL; Microglia; Toll-Like Receptor 4 | 2023 |
A double-layered gastric floating tablet for zero-order controlled release of dihydromyricetin: Design, development, and in vitro/in vivo evaluation.
Topics: Animals; Delayed-Action Preparations; Flavonols; Rabbits; Stomach; Tablets | 2023 |
An efficient cocrystallization strategy for separation of dihydromyricetin from vine tea and enhanced its antibacterial activity for food preserving application.
Topics: Anti-Bacterial Agents; Antioxidants; Bacteria; Flavonols; Tea | 2023 |
Thermal degradation of (2R, 3R)-dihydromyricetin in neutral aqueous solution at 100 ℃.
Topics: Chromatography, Liquid; Flavonols; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Water | 2024 |