Compounds > amoxicillin-potassium-clavulanate-combination

amoxicillin-potassium-clavulanate-combination and cefetamet

amoxicillin-potassium-clavulanate-combination has been researched along with cefetamet* in 2 studies

Other Studies

2 other study(ies) available for amoxicillin-potassium-clavulanate-combination and cefetamet

Article	Year
Effect of inoculum size on the in-vitro susceptibility to beta-lactam antibiotics of Moraxella catarrhalis isolates of different beta-lactamase types. Journal of medical microbiology, 1994, Volume: 40, Issue:4 The effect of inoculum size on the results of agar dilution MIC tests was assessed for 20 Moraxella catarrhalis isolates with BRO-1 enzyme, 20 with BRO-2 enzyme and 15 isolates that did not produce beta-lactamase. The compounds tested were ampicillin, coamoxiclav, cefaclor, cefixime and cefetamet, and the inocula were 10(4), 10(5), 10(6) and 10(7) cfu/spot. The MICs of ampicillin for BRO-1 and BRO-2 producers were consistently higher than those for non-producers at inocula of 10(7) cfu/spot but overlapped with those for non-producers at lower inocula. A small beta-lactamase-related inoculum effect was seen with coamoxiclav; small inoculum effects also occurred with cefaclor and cefixime but were not related to enzyme presence or type. MICs of cefetamet were the least affected by the inoculum size. For all the compounds, the degree of correlation between MICs and the inhibition zones observed in disk diffusion tests was independent of the inoculum used in the MIC tests. These data suggest that high inocula should be used to determine MICs of ampicillin for M. catarrhalis but that this precaution is unnecessary with the cephalosporins tested or with coamoxiclav. Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cefaclor; Cefixime; Cefotaxime; Ceftizoxime; Clavulanic Acids; Colony Count, Microbial; Drug Therapy, Combination; Microbial Sensitivity Tests; Moraxella catarrhalis	1994
In vitro activity of Ro 15-8074, a new oral cephalosporin, against Neisseria gonorrhoeae. Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:3 Ro 15-8074, a new cephalosporin the pivaloyloxymethylester of which (Ro 15-8075) is orally absorbable, showed greater in vitro activity than cefaclor against 48 Neisseria gonorrhoeae strains, including 25 penicillinase-producing strains. Unlike cefaclor, Ro 15-8074 was unaffected by increase in inoculum size, and it exhibited a remarkable stability against gonococcal beta-lactamase hydrolysis. Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; beta-Lactamases; Cefaclor; Ceftizoxime; Cephalosporins; Clavulanic Acids; In Vitro Techniques; Microbial Sensitivity Tests; Neisseria gonorrhoeae	1985

Article

Year

Effect of inoculum size on the in-vitro susceptibility to beta-lactam antibiotics of Moraxella catarrhalis isolates of different beta-lactamase types.

Journal of medical microbiology, 1994, Volume: 40, Issue:4

The effect of inoculum size on the results of agar dilution MIC tests was assessed for 20 Moraxella catarrhalis isolates with BRO-1 enzyme, 20 with BRO-2 enzyme and 15 isolates that did not produce beta-lactamase. The compounds tested were ampicillin, coamoxiclav, cefaclor, cefixime and cefetamet, and the inocula were 10(4), 10(5), 10(6) and 10(7) cfu/spot. The MICs of ampicillin for BRO-1 and BRO-2 producers were consistently higher than those for non-producers at inocula of 10(7) cfu/spot but overlapped with those for non-producers at lower inocula. A small beta-lactamase-related inoculum effect was seen with coamoxiclav; small inoculum effects also occurred with cefaclor and cefixime but were not related to enzyme presence or type. MICs of cefetamet were the least affected by the inoculum size. For all the compounds, the degree of correlation between MICs and the inhibition zones observed in disk diffusion tests was independent of the inoculum used in the MIC tests. These data suggest that high inocula should be used to determine MICs of ampicillin for M. catarrhalis but that this precaution is unnecessary with the cephalosporins tested or with coamoxiclav.

Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cefaclor; Cefixime; Cefotaxime; Ceftizoxime; Clavulanic Acids; Colony Count, Microbial; Drug Therapy, Combination; Microbial Sensitivity Tests; Moraxella catarrhalis

1994

In vitro activity of Ro 15-8074, a new oral cephalosporin, against Neisseria gonorrhoeae.

Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:3

Ro 15-8074, a new cephalosporin the pivaloyloxymethylester of which (Ro 15-8075) is orally absorbable, showed greater in vitro activity than cefaclor against 48 Neisseria gonorrhoeae strains, including 25 penicillinase-producing strains. Unlike cefaclor, Ro 15-8074 was unaffected by increase in inoculum size, and it exhibited a remarkable stability against gonococcal beta-lactamase hydrolysis.

Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; beta-Lactamases; Cefaclor; Ceftizoxime; Cephalosporins; Clavulanic Acids; In Vitro Techniques; Microbial Sensitivity Tests; Neisseria gonorrhoeae

1985