amoxicillin-potassium-clavulanate-combination and carprofen

A 4-year-old castrated male Chihuahua was evaluated because of unilateral vision loss following extraoral administration of a caudal maxillary nerve block during a dental procedure.. The menace response was absent in the left eye, but the pupillary light reflex was intact. Vitreal hemorrhages and opacities were present on ophthalmic examination of the left eye. Ultrasonographic findings were supportive of the clinical findings. The posterior lens capsule and retina appeared to be undisturbed.. Treatment consisted of administration of carprofen and prophylactic administration of amoxicillin-clavulanate. Vision was clinically normal with an intact menace response 1 week later.. Findings indicated that intravitreal injection of the local anesthetic agent should be considered as a potential complication when performing nerve blocks prior to dental procedures in dogs.

Topics: Amoxicillin-Potassium Clavulanate Combination; Anesthetics, Local; Animals; Blindness; Bupivacaine; Carbazoles; Dog Diseases; Dogs; Intravitreal Injections; Male; Medical Errors

A 9-year-old male Jack Russell Terrier with a history of travel to Thailand was presented with chronic lethargy, weight loss, unilateral anterior uveitis, pancytopenia, hyperglobulinemia, and proteinuria. Numerous trypomastigotes were found on a blood smear, and using molecular methods the parasite was identified as Trypanosoma evansi. After initial response to treatment, the dog experienced a relapse with central neurologic signs 88 days after initial presentation and died. Antibodies to T evansi were detected in both serum and cerebrospinal fluid (CSF) using a card agglutination test (CATT/T evansi), and PCR analysis of CSF for T evansi was positive. Findings at necropsy included marked non-purulent meningoencephalitis. Chronic infection with T evansi in a dog that returned to Germany following international travel highlights the risk associated with introduction of foreign animal diseases to Europe and the possibility of these infections becoming endemic. Detection of chronic infection and curative therapy of trypanosomiasis are challenging, and infection is usually fatal in the dog.

Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Protozoan; Antigens, Protozoan; Blood Transfusion; Carbazoles; Dog Diseases; Dogs; Drug Therapy, Combination; Fatal Outcome; Germany; Male; Pancytopenia; Suramin; Thailand; Travel; Trypanocidal Agents; Trypanosoma; Trypanosomiasis; Uveitis