Page last updated: 2024-08-23

amonafide and thiophenes

amonafide has been researched along with thiophenes in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abradelo, C; Báñez-Coronel, M; Braña, MF; Cacho, M; de Pascual-Teresa, B; Domínguez, MT; García, MA; Lacal, JC; Pozuelo, JM; Ramos, A; Rey-Stolle, MF; Yuste, M1
Cai, YJ; Chen, Y; Ding, J; Geng, MY; Huang, M; Luo, HB; Miao, ZH; Qian, XH; Qin, YX; Shen, X; Xu, YF; Yang, F; Zhu, H1
Cai, YJ; Ding, J; Feng, JM; Huang, M; Lu, JJ; Miao, ZH; Qian, XH; Tong, LJ; Xu, YF; Zhang, ZX; Zhu, H1

Other Studies

3 other study(ies) available for amonafide and thiophenes

ArticleYear
New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Adenine; Amides; Animals; Cell Line, Tumor; DNA; Drug Screening Assays, Antitumor; Furans; Humans; Imides; Intercalating Agents; Isoquinolines; Mice; Mice, Nude; Models, Molecular; Naphthalimides; Neoplasm Transplantation; Organophosphonates; Structure-Activity Relationship; Thiophenes; Transplantation, Heterologous

2004
R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:2

    Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Division; Cell Proliferation; Cytochromes c; DNA Topoisomerases, Type II; Enzyme Inhibitors; Female; Flow Cytometry; G2 Phase; Humans; Imides; In Situ Nick-End Labeling; Isoquinolines; Liver Neoplasms, Experimental; Mice; Mice, Inbred Strains; Naphthalimides; Organophosphonates; Poly(ADP-ribose) Polymerases; Sarcoma, Experimental; Thiophenes; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2007
Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.
    Neoplasia (New York, N.Y.), 2009, Volume: 11, Issue:11

    Topics: Adenine; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Cell Cycle Proteins; Checkpoint Kinase 2; DNA Breaks, Double-Stranded; DNA-Binding Proteins; Flow Cytometry; Fluorescent Antibody Technique; G2 Phase; HCT116 Cells; Humans; Naphthalimides; Organophosphonates; Protein Serine-Threonine Kinases; RNA, Small Interfering; Signal Transduction; Thiophenes; Transfection; Tumor Suppressor Proteins

2009