amodiaquine has been researched along with atovaquone in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 7 (36.84) | 2.80 |
| Authors | Studies |
|---|---|
| Bathurst, I; Burrows, JN; Charman, SA; Cross, RM; Flanigan, DL; Fronczek, FR; Guida, WC; Kyle, DE; LaCrue, AN; Maignan, JR; Manetsch, R; Monastyrskyi, A; Mutka, TS; Sáenz, FE; Shackleford, DM; White, KL; Wojtas, L | 1 |
| Coelho, L; Lukens, AK; Mazitschek, R; Moreira, R; Nogueira, F; Paulo, A; Santos, SA; Wirth, DF | 1 |
| Blake, LD; Burrows, JN; Casandra, D; Giarrusso, J; Kyle, DE; LaCrue, AN; Lichorowic, CL; Maignan, JR; Manetsch, R; Mutka, TS; Willis, PA | 1 |
| Blake, LD; Burrows, JN; Casandra, D; Kyle, DE; LaCrue, AN; Lichorowic, CL; Maignan, JR; Manetsch, R; Mashkouri, S; Monastyrskyi, A; Mutka, TS; Neelarapu, R; Willis, PA | 1 |
| Cheong, SL; Ng, CH; Tibon, NS | 1 |
| Baum, J; Bridgford, JL; Charman, SA; Churchyard, A; Crespo, B; Deni, I; Fidock, DA; Gahalawat, S; Gamo, FJ; Laleu, B; Lawong, A; Mittal, N; Mok, S; Niederstrasser, H; Okombo, J; Palmer, MJ; Phillips, MA; Posner, B; Ready, JM; Striepen, J; Winzeler, E; Wittlin, S; Yeo, T; Zhou, A | 1 |
| Asakawa, AH; Brockmeyer, F; Casandra, D; Huang, L; Kyle, DE; LaCrue, AN; Maher, SP; Maignan, JR; Manetsch, R; Mashkouri, S; Monastyrskyi, A; Padin-Irizarry, V; Parvatkar, PT; Sakhno, YI; Zhao, Y | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Hutchinson, D; Kremsner, PG; Nkeyi, M; Philipps, J; Radloff, PD | 1 |
| Bagaphou, T; Binder, RK; Borrmann, S; Faucher, JF; Kremsner, PG; Lell, B; Matsiegui, PB; Miller, G; Missinou, MA; Pabisch, S; Rezbach, P | 1 |
| Björkman, A; Gil, JP; Mariga, ST; Wernsdorfer, WH | 1 |
| Deharo, E; Garavito, G; Maurel, S; Monje, MC; Nepveu, F; Valentin, A | 1 |
| Blair, S; Deharo, E; Pabón, A | 1 |
| Almelli, T; Basco, LK; Debue, C; Djaman Allico, J; Foumane Ngane, V; Tahar, R; Whegang Youdom, S | 1 |
| Combrinck, JM; Egan, TJ; Fong, KY; Gibhard, L; Smith, PJ; Wright, DW | 1 |
| Lachish, T; Schwartz, E | 1 |
| Anvikar, AR; Ashley, EA; Chandramohan, D; Cohee, LM; D'Alessandro, U; Genton, B; Gilder, ME; Guérin, PJ; Juma, E; Kalilani-Phiri, L; Kennon, K; Kuepfer, I; Laufer, MK; Lwin, KM; Mansoor, R; McGready, R; Meshnick, SR; Mosha, D; Mwapasa, V; Mwebaza, N; Nambozi, M; Ndiaye, JA; Nosten, F; Nyunt, M; Ogutu, B; Parikh, S; Paw, MK; Phyo, AP; Pimanpanarak, M; Piola, P; Rijken, MJ; Saito, M; Sriprawat, K; Stepniewska, K; Tagbor, HK; Tarning, J; Tinto, H; Valéa, I; Valecha, N; White, NJ; Wiladphaingern, J | 1 |
| Blanshard, A; Hine, P | 1 |
| Abla, N; Chalon, S; Chughlay, MF; Haouala, A; Hutter, B; Lorch, U; Macintyre, F; Marie Tchouatieu, A | 1 |
3 review(s) available for amodiaquine and atovaquone
| Article | Year |
|---|---|
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines | 2020 |
Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis.
Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clindamycin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 2020 |
Atovaquone-proguanil for treating uncomplicated Plasmodium falciparum malaria.
Topics: Adult; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Atovaquone; Cameroon; Child; Colombia; Drug Combinations; Ethiopia; Humans; Malaria, Falciparum; Mefloquine; Proguanil; Randomized Controlled Trials as Topic; Thailand; Treatment Failure | 2021 |
4 trial(s) available for amodiaquine and atovaquone
| Article | Year |
|---|---|
Atovaquone and proguanil for Plasmodium falciparum malaria.
Topics: Acute Disease; Adult; Amodiaquine; Antimalarials; Atovaquone; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Gabon; Humans; Malaria, Falciparum; Male; Naphthoquinones; Proguanil; Time Factors; Treatment Outcome | 1996 |
Atovaquone and proguanil versus amodiaquine for the treatment of Plasmodium falciparum malaria in African infants and young children.
Topics: Amodiaquine; Animals; Antimalarials; Atovaquone; Child; Drug Combinations; Drug Tolerance; Female; Humans; Infant; Malaria, Falciparum; Male; Naphthoquinones; Proguanil; Treatment Outcome | 2003 |
Randomized trial of artesunate-amodiaquine, atovaquone-proguanil, and artesunate-atovaquone-proguanil for the treatment of uncomplicated falciparum malaria in children.
Topics: Amodiaquine; Antimalarials; Artemisinins; Atovaquone; Cameroon; Child, Preschool; Cytochromes b; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Treatment Outcome | 2014 |
Unanticipated CNS Safety Signal in a Placebo-Controlled, Randomized Trial of Co-Administered Atovaquone-Proguanil and Amodiaquine.
Topics: Amodiaquine; Antimalarials; Atovaquone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Falciparum; Male; Proguanil; Treatment Outcome | 2022 |
12 other study(ies) available for amodiaquine and atovaquone
| Article | Year |
|---|---|
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.
Topics: Animals; Antimalarials; Humans; Inhibitory Concentration 50; Malaria; Mice; Microsomes, Liver; Parasitemia; Plasmodium; Plasmodium berghei; Quinolones; Structure-Activity Relationship | 2014 |
Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype.
Topics: Antimalarials; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Indoles; Malaria; Molecular Structure; Niacinamide; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2015 |
ICI 56,780 Optimization: Structure-Activity Relationship Studies of 7-(2-Phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity.
Topics: Animals; Antimalarials; Dose-Response Relationship, Drug; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Quinolones; Structure-Activity Relationship | 2016 |
Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure-Activity and Structure-Property Relationship Studies.
Topics: Animals; Antimalarials; Drug Design; Humans; Mice; Piperazine; Plasmodium falciparum; Quinolones; Solubility; Structure-Activity Relationship | 2018 |
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in
Topics: Amides; Antimalarials; Drug Resistance, Microbial; Hemeproteins; Hemoglobins; Hep G2 Cells; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Small Molecule Libraries; Structure-Activity Relationship; Tetrazoles | 2021 |
Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1
Topics: Administration, Oral; Animals; Antimalarials; Cyclization; Disease Models, Animal; Ethers; Female; Half-Life; Hydrogen-Ion Concentration; Malaria; Mice; Mice, Inbred BALB C; Plasmodium falciparum; Prodrugs; Quinolones; Solubility; Structure-Activity Relationship | 2021 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Pharmacodynamic interactions of amodiaquine and its major metabolite desethylamodiaquine with artemisinin, quinine and atovaquone in Plasmodium falciparum in vitro.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Atovaquone; Cells, Cultured; Drug Synergism; Naphthoquinones; Plasmodium falciparum; Quinine; Sesquiterpenes; Species Specificity | 2005 |
A non-radiolabeled heme-GSH interaction test for the screening of antimalarial compounds.
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Chloroquine; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Glutathione; Heme; Indicators and Reagents; Mefloquine; Methylene Blue; o-Phthalaldehyde; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Spectrometry, Fluorescence | 2007 |
Plasmodium falciparum: Solanum nudum SN-1 steroid antiplasmodial activity when combined with antimalarial drugs.
Topics: Amodiaquine; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Synergism; Erythrocytes; Flow Cytometry; Humans; Phytosterols; Plasmodium falciparum; Quinine; Solanum; Trophozoites | 2011 |
Optimization of a multi-well colorimetric assay to determine haem species in Plasmodium falciparum in the presence of anti-malarials.
Topics: Amodiaquine; Antimalarials; Atovaquone; Chloroquine; Colorimetry; Heme; Plasmodium falciparum; Pyrimethamine; Trophozoites | 2015 |
Artemisinin-based combination therapy (ACT) versus atovaquone-proguanil: do not choose between but, rather, combine them.
Topics: Amodiaquine; Antimalarials; Artemisinins; Atovaquone; Female; Humans; Malaria, Falciparum; Male; Proguanil | 2016 |