amodiaquine has been researched along with artemisinin in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.45) | 18.7374 |
| 1990's | 4 (5.80) | 18.2507 |
| 2000's | 20 (28.99) | 29.6817 |
| 2010's | 35 (50.72) | 24.3611 |
| 2020's | 9 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Cheong, SL; Ng, CH; Tibon, NS | 1 |
| Baum, J; Bridgford, JL; Charman, SA; Churchyard, A; Crespo, B; Deni, I; Fidock, DA; Gahalawat, S; Gamo, FJ; Laleu, B; Lawong, A; Mittal, N; Mok, S; Niederstrasser, H; Okombo, J; Palmer, MJ; Phillips, MA; Posner, B; Ready, JM; Striepen, J; Winzeler, E; Wittlin, S; Yeo, T; Zhou, A | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Chu, YH; Shao, BR; Ye, XY | 2 |
| Trigg, PI | 1 |
| Bourdeau, EF; Childs, GE; Milhous, WK; Pang, L; Wimonwattratee, T | 1 |
| Druilhe, P; Gentilini, M; Stahel, E | 1 |
| Debaert, M | 1 |
| Björkman, A; Gupta, S; Mariga, ST; Thapar, MM; Wernsdorfer, WH | 1 |
| Fidock, DA; Sidhu, AB; Verdier-Pinard, D | 1 |
| Majori, G | 1 |
| Ali, AS; Bhattarai, A; Björkman, A; Maini-Thapar, M | 1 |
| Björkman, A; Gil, JP; Mariga, ST; Wernsdorfer, WH | 1 |
| Bakyaita, N; Banek, K; Dorsey, G; Kamya, MR; Kilian, A; Kironde, F; Nsobya, SL; Reingold, A; Rosenthal, PJ; Slater, M; Staedke, SG; Talisuna, A; Wabwire-Mangen, F; Yeka, A | 1 |
| Juma, EA; Lau, J; Obonyo, CO; Ogutu, BR; Vulule, JM | 1 |
| Björkman, A; Gil, JP; Hamrin, J; Holmgren, G; Mårtensson, A; Svärd, J | 1 |
| Andrianina, NN; Jahevitra, M; Ménard, D; Ramiandrasoa, Z; Randriamanantena, A; Rasoarilalao, N; Ratsimbasoa, A; Raveloson, A; Tuseo, L | 1 |
| Hampton, T | 1 |
| Agyei-Baffour, P; Ajayi, IO; Balyeku, A; Bateganya, F; Browne, EN; Cousens, S; Doamekpor, L; Garshong, B; Munguti, K; Pagnoni, F; Yusuf, B | 1 |
| Ashley, EA; Balkan, S; Bukirwa, H; Checchi, F; Dorsey, G; Guthmann, JP; Olliaro, P; Pinoges, L; Taylor, WR; Turyakira, E; Urruta, PP; van den Broek, I; van Herp, M; Zongo, I | 1 |
| Briand, V; Buffet, PA; Danis, M; Mazier, D; Rénia, L; Thellier, M | 1 |
| Balogun, ST; Gbotosho, GO; Happi, CT; Sowunmi, A | 1 |
| Engl, M; Gluderer, D; Ogwang, M; Ploner, F; Ploner, M; Prugger, C; Wernsdorfer, G; Wernsdorfer, WH | 1 |
| Lai, CS; Mansor, SM; Muniandy, A; Nair, NK; Navaratnam, V; Olliaro, PL | 1 |
| Ajeigbe, KO; Nwobodo, EO; Olaleye, SB | 1 |
| Boly, MD; Deloron, P; Faucher, JF; Houzé, S; Le Bras, J | 1 |
| Kouyaté, B; Meissner, P; Müller, O; Schirmer, RH; Sié, A | 1 |
| Oguonu, T; Okafor, HU; Shu, EN | 1 |
| Blair, S; Deharo, E; Pabón, A | 1 |
| Akao, N; Anyan, WK; Asahi, H; Ayi, I; Boakye, DA; Kumagai, T; Kwansa-Bentum, B; Ohta, N; Otchere, J; Suzuki, T; Wilson, MD | 1 |
| Arango, EM; Carmona-Fonseca, J; Upegui, YA | 1 |
| Chavchich, M; Dai, B; Edstein, MD; Phong, NC; Quang, HH; Shanks, GD; Thanh, NX; Trung, TN | 1 |
| Amuasi, JH; Boakye, I; Diap, G; Jambai, A; Karikari, P; Kiechel, JR; Lahai, WK; Louie, KS; Nguah, SB | 1 |
| Beeson, JG; Goodman, CD; Langer, C; McFadden, GI; Wilson, DW | 1 |
| Adesina, O; Bassi, PU; Coulter, D; Isah, A; Jalo, I; Kalat, M; Nwoasu, SC; Nyong, EE; Osakwe, AI; Osungwu, F; Pal, S; Suku, C; Ugochukwu, C; Wallberg, M; Wammanda, RD | 1 |
| Cooksey, R; Dahlström, S; Fairhurst, RM; Flegg, JA; Guerin, PJ; Johnson, JD; Le Bras, J; Le Nagard, H; Lim, P; Ménard, D; Mentré, F; Murillo, C; Musset, L; Noedl, H; Nosten, F; Nsobya, SL; Pradines, B; Quashie, NB; Sibley, CH; Sinou, V; Sriprawat, K; Woodrow, CJ | 1 |
| Dondorp, AM; Faiz, MA; Hien, TT; Mokuolu, OA; Pukrittayakamee, S; White, NJ | 1 |
| D'Alessandro, U; Grobusch, MP; Lutumba, P; Muhindo Mavoko, H; Nabasumba, C; Tinto, H; Van Geertruyden, JP | 1 |
| Aubouy, A; Dahlström, S; Deloron, P; Ezinmègnon, S; Faucher, JF; Houzé, P; Houzé, S; Kendjo, E; Le Bras, J; Maïga-Ascofaré, O; Massougbodji, A; Wakpo, A | 1 |
| Cremers, S; Fidock, DA; Henrich, PP; Kyle, DE; O'Brien, C; Sáenz, FE | 1 |
| Abiola, A; Faye, B; Folly, K; Gaye, O; Lo, AC; Ndiaye, JL; Ndiaye, LA; Ndiaye, M; Sow, D; Sylla, K; Tine, RC | 1 |
| Bala, N; Betuela, I; Davis, TM; Hetzel, MW; Lavu, EK; Page-Sharp, M; Pulford, J | 1 |
| Agomo, C; Agomo, P; Aina, O; Banjo, O; Meremikwu, M; Ntadom, G; Odey, F; Ogala, W; Oguche, S; Ogunrinde, G; Okafor, HU; Okuboyejo, T; Sofola, T; Sowunmi, A; Watila, I | 1 |
| Adedeji, ON; Ademowo, OG; Bolaji, OO; Falade, CO; Osonuga, OA | 1 |
| d'Alessandro, U; Dahal, P; Dorsey, G; Guerin, PJ; Nsanzabana, C; Price, RN; Sibley, CH; Stepniewska, K; Talisuna, AO | 1 |
| Aderoyeje, T; Adewoye, EO; Akano, K; Ayede, AI; Fatunmbi, B; Ntadom, G; Sowunmi, A | 2 |
| Baird, JK; Boni, MF; Dondorp, AM; Farrar, J; Lam, HM; Nguyen, TD; Olliaro, P; Thwaites, GE; White, NJ | 1 |
| Acheampong, PR; Antwi, GD; Bart Plange, C; Cairns, M; Chandramohan, D; Tagbor, H | 1 |
| Ajayi, I; Ajumobi, O; Bamiselu, OF; Dairo, D; Fawole, O; Oladimeji, A; Steven, Y | 1 |
| Maxmen, A | 1 |
| Fairhurst, RM; Imwong, M; Kwiatkowski, DP; Lim, P; Miotto, O; Srimuang, K; Woodrow, CJ | 1 |
| Liu, XJ; Peng, HJ; Wei, HX; Xia, J; Zhou, LJ | 1 |
| Allan, EL; Bell, D; Kaur, H; Lozama, A; Wilson, BK | 1 |
| Amalvict, R; Bercion, R; Diatta, B; Diawara, S; Fall, B; Gueye, MW; Kounta, MB; Lo, G; Madamet, M; Nakoulima, A; Pradines, B; Wade, KA | 1 |
| Clark, RL | 1 |
| Ajeigbe, KO; Emikpe, BO; Olaleye, SB | 1 |
| Anh, CX; Birrell, GW; Chavchich, M; Edstein, MD; Quang, NN; Rowcliffe, K; Travers, T; van Breda, K | 1 |
| Baska, KS; Dalal, S; Dhingra, SK; Fidock, DA; Garcia, CRS; Klein, MS; Klemba, M; Krishna, S; Lee, AH; Lewis, IA; Llinás, M; Roepe, PD; Rubiano, K; Singh, MK; Siriwardana, A | 1 |
| Cumming, BM; Goldring, JPD | 1 |
| Beavogui, AH; Borghini-Fuhrer, I; Djimdé, AA; Duparc, S; Felices, M; Funck-Brentano, C; Khan, Y; Ouedraogo, JB; Ouologuem, N; Sagara, I; Sirima, SB; Soulama, I; Voiriot, P | 1 |
| Amaratunga, C; Amato, R; Anvikar, AR; Ashley, E; Baidya, S; Behera, PK; Callery, JJ; Chau, NH; Cheah, PY; Chotivanich, K; Chutasmit, K; Day, NPJ; Dhorda, M; Dondorp, AM; Fairhurst, RM; Faiz, A; Fanello, C; Gantait, K; Ghosh, T; Gonçalves, S; Grobusch, MP; Hanboonkunupakarn, B; Heaton, J; Hien, TT; Hlaing, TM; Hoa, NT; Hoglund, RM; Huy, R; Imwong, M; Jacob, CG; Jittamala, P; Kaewmok, W; Kwiatkowski, DP; Lek, D; Lin, K; Mao, S; Maude, RJ; Mayxay, M; Miotto, O; Mohanty, AK; Mukaka, M; Newton, PN; Onyamboko, M; Oun, S; Pearson, RD; Peto, TJ; Pukrittayakamee, S; Pyae Phyo, A; Runcharern, R; Saelow, C; Satpathi, P; Satpathi, S; Smithuis, F; Sovann, Y; Sreng, S; Suon, S; Tarning, J; Thanh, NV; Thant, M; Thuy-Nhien, NT; Tripura, A; Tripura, R; Ul Islam, A; Valecha, N; van der Pluijm, RW; van Vugt, M; von Seidlein, L; Waithira, N; White, NJ; Winterberg, M; Woodrow, CJ; Yen, S | 1 |
| Bihoun, B; Derra, K; Kazienga, A; Nakanabo-Diallo, S; Pagnoni, F; Rouamba, E; Rouamba, T; Samadoulougou-Kirakoya, F; Sondo, P; Sorgho, H; Tarnagda, Z; Tinto, H; Valea, I | 1 |
| Adeniyi, OM; Ajibaye, O; Aremu, OI; Asogwa, N; Babamale, OA; Fakayode, O; Fatoba, IM; Iyiola, OA; Omotesho, OB; Opeyemi, OA; Salawu, KM; Shittu, O | 1 |
| Anywar, DA; Auma, MA; Balikagala, B; Emoto, S; Fukuda, N; Hashimoto, M; Hirai, M; Horii, T; Ikeda, M; Kataoka, M; Katuro, OT; Kimura, E; Mita, T; Mori, T; Obwoya, PS; Odongo-Aginya, EI; Ogwang, M; Opio, W; Palacpac, NMQ; Sakurai-Yatsushiro, M; Sekihara, M; Tachibana, SI; Yamauchi, M; Yatsushiro, S | 1 |
| Bamadio, A; Chico, RM; Cohee, LM; Coumare, S; Dara, A; Diarra, M; Djimde, AA; Doumbo, OK; Kodio, A; Maiga, H; Opondo, C; Sagara, I; Sidibe, B; Tekete, M; Traore, OB; Traore, ZI | 1 |
| Abdelkader, O; Boulotigam, K; Djimadoum, M; Djimrassengar, H; Doderer-Lang, C; Hassoumi, M; Issa, AH; Issa, MS; Mahamat, MHT; Menard, D; Ndihiokubwayo, JB; Rasmussen, C; Saleh, IDM; Warsame, M | 1 |
9 review(s) available for amodiaquine and artemisinin
| Article | Year |
|---|---|
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines | 2020 |
[Developments in anti-malaria agents: chemical data, structure-activity relationships].
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Resistance; Drugs, Chinese Herbal; Folic Acid Antagonists; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship | 2001 |
[Combined antimalarial therapy using artemisinin].
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2004 |
Amodiaquine combined with sulfadoxine/pyrimethamine versus artemisinin-based combinations for the treatment of uncomplicated falciparum malaria in Africa: a meta-analysis.
Topics: Africa; Amodiaquine; Artemisinins; Drug Combinations; Humans; Malaria, Falciparum; Multicenter Studies as Topic; Pyrimethamine; Randomized Controlled Trials as Topic; Sesquiterpenes; Sulfadoxine | 2007 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine | 2014 |
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data.
Topics: Africa; Africa South of the Sahara; Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prospective Studies; Quinolines | 2015 |
Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data.
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Host-Parasite Interactions; Humans; Logistic Models; Malaria, Falciparum; Male; Microscopy; Middle Aged; Plasmodium falciparum; Proportional Hazards Models; Recurrence | 2016 |
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Risk; Sulfadoxine | 2017 |
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens | 2017 |
18 trial(s) available for amodiaquine and artemisinin
| Article | Year |
|---|---|
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda.
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Humans; Infant; Infections; Malaria; Male; Pyrimethamine; Risk Factors; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Uganda | 2005 |
Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Madagascar; Malaria, Falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Ethanolamines; Feasibility Studies; Fever; Fluorenes; Ghana; Humans; Infant; Malaria; Nigeria; Patient Acceptance of Health Care; Treatment Outcome; Uganda | 2008 |
Effects of amodiaquine, artesunate, and artesunate-amodiaquine on Plasmodium falciparum malaria-associated anaemia in children.
Topics: Amodiaquine; Anemia; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Treatment Outcome | 2009 |
Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in c
Topics: Administration, Oral; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Electrochemistry; Humans; Solid Phase Extraction | 2009 |
Therapeutic efficacy and effect on gametocyte carriage of an artemisinin and a non-based combination treatment in children with uncomplicated P. falciparum malaria, living in an area with high-level chloroquine resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Gametogenesis; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfalene; Treatment Outcome | 2010 |
Efficacy of different primaquine-based antimalarial regimens against Plasmodium falciparum gametocytemia.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Colombia; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Germ Cells; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Parasitemia; Plasmodium falciparum; Primaquine; Pyrimethamine; Sulfadoxine; Treatment Outcome; Young Adult | 2012 |
The efficacy and tolerability of artemisinin-piperaquine (Artequick®) versus artesunate-amodiaquine (Coarsucam™) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam.
Topics: Adolescent; Adult; Amodiaquine; Animals; Artemisinins; Blood; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Time Factors; Treatment Outcome; Vietnam; Young Adult | 2012 |
Impact of retreatment with an artemisinin-based combination on malaria incidence and its potential selection of resistant strains: study protocol for a randomized controlled clinical trial.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Clindamycin; Clinical Protocols; Democratic Republic of the Congo; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Incidence; Infant; Longitudinal Studies; Malaria, Falciparum; Male; Plasmodium falciparum; Quinine; Recurrence; Research Design; Retreatment; Time Factors; Treatment Outcome; Uganda | 2013 |
Monitoring the efficacy and safety of three artemisinin based-combinations therapies in Senegal: results from two years surveillance.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Population Surveillance; Quinolines; Senegal; Young Adult | 2013 |
Efficacy of artemisinin-based combination treatments of uncomplicated falciparum malaria in under-five-year-old Nigerian children.
Topics: Amodiaquine; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Nigeria; Parasitemia; Prevalence; Treatment Outcome | 2014 |
Validation and pharmacokinetic application of a high-performance liquid chromatographic technique for determining the concentrations of amodiaquine and its metabolite in plasma of patients treated with oral fixed-dose amodiaquine-artesunate combination in
Topics: Administration, Oral; Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Male; Nigeria; Young Adult | 2015 |
Temporal changes in haematocrit following artemisinin-based combination treatments of uncomplicated falciparum malaria in children.
Topics: Administration, Intravenous; Adolescent; Amodiaquine; Anemia; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Combined Modality Therapy; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Hematocrit; Humans; Infant; Malaria, Falciparum; Male; Prospective Studies; Treatment Outcome | 2015 |
Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Ghana; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Pyrimethamine; Quinolines; Rain; Seasons; Sulfadoxine | 2016 |
Clinical illness and outcomes in Nigerian children with late-appearing anaemia after artemisinin-based combination treatments of uncomplicated falciparum malaria.
Topics: Adolescent; Amodiaquine; Anemia; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Prognosis; Quinolines; Risk Factors; Time Factors; Treatment Outcome | 2016 |
Analysis of anti-malarial resistance markers in pfmdr1 and pfcrt across Southeast Asia in the Tracking Resistance to Artemisinin Collaboration.
Topics: Amodiaquine; Antimalarials; Artemisinins; Asia, Southeastern; DNA, Protozoan; Drug Resistance; Ethanolamines; Fluorenes; Gene Frequency; High-Throughput Nucleotide Sequencing; Humans; Lumefantrine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation, Missense; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins | 2016 |
Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.
Topics: Adolescent; Adult; Amodiaquine; Anthraquinones; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Treatment Outcome; Young Adult | 2020 |
Overall and Gender-Specific Effects of Intermittent Preventive Treatment of Malaria with Artemisinin-Based Combination Therapies among Schoolchildren in Mali: A Three-Group Open Label Randomized Controlled Trial.
Topics: Amodiaquine; Anemia; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; Humans; Malaria; Malaria, Falciparum; Mali; Pyrimethamine; Sulfadoxine | 2022 |
42 other study(ies) available for amodiaquine and artemisinin
| Article | Year |
|---|---|
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in
Topics: Amides; Antimalarials; Drug Resistance, Microbial; Hemeproteins; Hemoglobins; Hep G2 Cells; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Small Molecule Libraries; Structure-Activity Relationship; Tetrazoles | 2021 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
[The blood schizontocidal effects of pyronaridine, amodiaquine, mefloquine and qinghaosu on mice infected with Plasmodium berghei].
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Resistance; Female; Malaria; Male; Mefloquine; Mice; Naphthyridines; Plasmodium berghei; Sesquiterpenes | 1992 |
Comparison of effects of pyronaridine, amodiaquine, mefloquine and qinghaosu on rodent malaria.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Resistance; Female; Malaria; Male; Mefloquine; Mice; Naphthyridines; Plasmodium berghei; Sesquiterpenes | 1992 |
Drug use and design in the nineties.
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine | 1991 |
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Butylated Hydroxytoluene; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Mefloquine; Molecular Structure; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Sesquiterpenes; Thailand | 1991 |
Antagonism of chloroquine with other antimalarials.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Interactions; Drug Resistance; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1988 |
Plasmodium falciparum: in vitro interactions of artemisinin with amodiaquine, pyronaridine, and chloroquine.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Interactions; Drug Resistance; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes | 2002 |
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.
Topics: Alleles; Amodiaquine; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Genes, Protozoan; Haplotypes; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine; Sesquiterpenes; Transfection; Verapamil | 2002 |
Amodiaquine during pregnancy.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Safety; Sesquiterpenes; Treatment Outcome | 2004 |
Pharmacodynamic interactions of amodiaquine and its major metabolite desethylamodiaquine with artemisinin, quinine and atovaquone in Plasmodium falciparum in vitro.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Atovaquone; Cells, Cultured; Drug Synergism; Naphthoquinones; Plasmodium falciparum; Quinine; Sesquiterpenes; Species Specificity | 2005 |
Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East Africa.
Topics: Amodiaquine; Animals; Artemisinins; Child, Preschool; Clinical Trials as Topic; Humans; Kenya; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Odds Ratio; Plasmodium falciparum; Protozoan Proteins; Selection, Genetic; Tanzania | 2007 |
Antimalarial drugs--here and on the horizon.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Drug Combinations; Drug Industry; Drug Resistance; GTP-Binding Proteins; Humans; Interdisciplinary Communication; Malaria; Medical Missions; Plasmodium falciparum; Sesquiterpenes; Signal Transduction | 2007 |
Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children.
Topics: Africa; Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Databases as Topic; Drug Combinations; Ethanolamines; Fluorenes; Genotype; Humans; Infant; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2008 |
Intermittent preventive antimalarial treatment to children (IPTc): firebreak or fire trap?
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Decision Making; Drug Administration Schedule; Drug Combinations; Drug Resistance; Humans; Infant; Malaria; Pyrimethamine; Sulfadoxine | 2008 |
Malariological baseline survey and in vitro antimalarial drug resistance in Gulu district, Northern Uganda.
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Developing Countries; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; Ethanolamines; Evidence-Based Medicine; Female; Fluorenes; Health Surveys; Humans; Incidence; Infant; Lumefantrine; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Refugees; Uganda; Young Adult | 2008 |
Effects of amodiaquine hydrochloride and artemisinin on indomethacin-induced lipid peroxidation in rats.
Topics: Amodiaquine; Animals; Artemisinins; Gastric Juice; Indomethacin; Lipid Peroxidation; Rats; Rats, Wistar; Stomach Ulcer | 2008 |
PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria.
Topics: Amodiaquine; Antigens, Protozoan; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Benin; Blood; Child, Preschool; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Ethanolamines; Fluorenes; Follow-Up Studies; Humans; Infant; L-Lactate Dehydrogenase; Malaria, Falciparum; Microscopy; Molecular Diagnostic Techniques; Protozoan Proteins; Pyrimethamine; Sensitivity and Specificity; Sulfadoxine; Treatment Outcome | 2009 |
Artemisinin resistance on the Thai-Cambodian border.
Topics: Amodiaquine; Antimalarials; Artemisinins; Burkina Faso; Cambodia; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Thailand | 2009 |
Plasmodium falciparum: Solanum nudum SN-1 steroid antiplasmodial activity when combined with antimalarial drugs.
Topics: Amodiaquine; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Synergism; Erythrocytes; Flow Cytometry; Humans; Phytosterols; Plasmodium falciparum; Quinine; Solanum; Trophozoites | 2011 |
Administrative practices of health professionals and use of artesunate-amodiaquine by community members for treating uncomplicated malaria in southern Ghana: implications for artemisinin-based combination therapy deployment.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Community-Based Participatory Research; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Drug Utilization; Female; Ghana; Health Care Surveys; Humans; Infant; Male; Middle Aged; Nurses; Pharmacists; Pharmacy Technicians; Physicians; Practice Patterns, Physicians'; Rural Population; Surveys and Questionnaires; Urban Population | 2011 |
Access to artemisinin-combination therapy (ACT) and other anti-malarials: national policy and markets in Sierra Leone.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Drug Costs; Geography; Health Policy; Health Services Accessibility; Humans; Malaria; Organizations, Nonprofit; Pharmacies; Poverty; Private Sector; Public Sector; Sierra Leone | 2012 |
Defining the timing of action of antimalarial drugs against Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Flow Cytometry; High-Throughput Screening Assays; Hydroxamic Acids; Inhibitory Concentration 50; Mefloquine; Merozoites; Plasmodium falciparum; Quinine; Quinolines; Schizonts; Time Factors | 2013 |
Safety of Artemisinin-Based Combination Therapies in Nigeria: A Cohort Event Monitoring Study.
Topics: Adolescent; Adult; Amodiaquine; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Child, Preschool; Cohort Studies; Ethanolamines; Female; Fluorenes; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Nigeria; Pregnancy; Prospective Studies; Young Adult | 2013 |
High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.
Topics: Amodiaquine; Antimalarials; Artemisinins; Automation, Laboratory; Chloroquine; Drug Resistance; Drug Therapy, Combination; High-Throughput Screening Assays; Internet; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine | 2013 |
Plasmodium falciparum Polymorphisms associated with ex vivo drug susceptibility and clinical effectiveness of artemisinin-based combination therapies in Benin.
Topics: Amodiaquine; Antimalarials; Artemisinins; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Lumefantrine; Male; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Quinine; Sulfadoxine | 2014 |
Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Resistance; Female; Flow Cytometry; Malaria, Falciparum; Mefloquine; Mice; Naphthyridines | 2014 |
Quality of antimalarial drugs and antibiotics in Papua New Guinea: a survey of the health facility supply chain.
Topics: Amodiaquine; Amoxicillin; Antimalarials; Artemether; Artemisinins; Biosimilar Pharmaceuticals; Chloroquine; Drug Resistance; Health Facilities; Humans; Malaria, Falciparum; Malaria, Vivax; Papua New Guinea; Primaquine; Quality Control; Quinine | 2014 |
Optimum population-level use of artemisinin combination therapies: a modelling study.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Administration Schedule; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Models, Biological; Plasmodium falciparum; Quinolines; Treatment Failure | 2015 |
Adherence to malaria diagnosis and treatment guidelines among healthcare workers in Ogun State, Nigeria.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Case Management; Cross-Sectional Studies; Delivery of Health Care; Diagnostic Tests, Routine; Drug Prescriptions; Drug Therapy, Combination; Female; Guideline Adherence; Health Facilities; Health Personnel; Humans; Malaria; Male; Middle Aged; Nigeria; Practice Guidelines as Topic; Private Sector; Public Sector; Young Adult | 2016 |
Busting the billion-dollar myth: how to slash the cost of drug development.
Topics: Africa; Amodiaquine; Anti-Bacterial Agents; Artemisinins; Benzamides; Boron Compounds; Child; Clinical Trials as Topic; Cooperative Behavior; Developed Countries; Developing Countries; Drug Approval; Drug Combinations; Drug Costs; Drug Discovery; Drug Industry; Drug Repositioning; Drug Resistance, Microbial; Female; Humans; Malaria; Neglected Diseases; Negotiating; Nitroimidazoles; Organizations, Nonprofit; Sample Size; Trypanosomiasis, African; World Health Organization | 2016 |
A New Handheld Device for the Detection of Falsified Medicines: Demonstration on Falsified Artemisinin-Based Therapies from the Field.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Computers, Handheld; Counterfeit Drugs; Drug Combinations; Drug Contamination; Equatorial Guinea; Ghana; Humans; Mobile Applications; Quality Control; Sensitivity and Specificity; Spectrophotometry, Infrared | 2017 |
Confirmation of Plasmodium falciparum in vitro resistance to monodesethylamodiaquine and chloroquine in Dakar, Senegal, in 2015.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Plasmodium falciparum; Senegal | 2017 |
Effects of artemisinin, with or without lumefantrine and amodiaquine on gastric ulcer healing in rat.
Topics: Amodiaquine; Animals; Artemisinins; C-Reactive Protein; Drug Therapy, Combination; Lumefantrine; Male; Neutrophil Infiltration; Rats; Rats, Wistar; Stomach Ulcer | 2018 |
Comparison of the Pharmacokinetics and Ex Vivo Antimalarial Activities of Artesunate-Amodiaquine and Artemisinin-Piperaquine in Healthy Volunteers for Preselection Malaria Therapy.
Topics: Amodiaquine; Antimalarials; Area Under Curve; Artemisinins; Biotransformation; Drug Administration Schedule; Drug Combinations; Half-Life; Healthy Volunteers; Humans; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Tablets; Young Adult | 2018 |
Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter.
Topics: Amodiaquine; Antimalarials; Artemisinins; Calcium; Cells, Cultured; Chloroquine; Drug Resistance, Multiple; Erythrocytes; Gene Expression; Hemoglobins; Host-Parasite Interactions; Humans; Ion Transport; Ionophores; Membrane Transport Proteins; Monensin; Mutation; Nigericin; Plasmodium falciparum; Protozoan Proteins; Pyrrolidinones | 2018 |
Monocyte phagocytosis of malaria β-haematin in the presence of artemisinin, amodiaquine, chloroquine, doxycycline, primaquine, pyrimethamine and quinine.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Cell Count; Cell Line; Chloroquine; Doxycycline; Electron Probe Microanalysis; Heme; Hemeproteins; Humans; Leukocytes, Mononuclear; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Monocytes; Peroxidase; Phagocytosis; Primaquine; Pyrimethamine; Quinine; Spectrophotometry; Temperature; U937 Cells | 2019 |
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method.
Topics: Adolescent; Amodiaquine; Antimalarials; Arrhythmias, Cardiac; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Heart Rate; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Male; Quinolines; Young Adult | 2019 |
Optimal Approach and Strategies to Strengthen Pharmacovigilance in Sub-Saharan Africa: A Cohort Study of Patients Treated with First-Line Artemisinin-Based Combination Therapies in the Nanoro Health and Demographic Surveillance System, Burkina Faso.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Burkina Faso; Child; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Pharmacovigilance; Pregnancy; Prospective Studies; Structure-Activity Relationship | 2020 |
Clinical Probe of Cyp2C8*2 Mutants in a Malaria Hyperendemic Zone: Evidence from North-Central, Nigeria.
Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Cytochrome P-450 CYP2C8; Drug Resistance; Female; Humans; Malaria; Male; Nigeria; Pharmacogenomic Testing; Plasmodium falciparum | 2020 |
Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in Northern Uganda.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Lumefantrine; Mefloquine; Plasmodium falciparum; Quinine; Uganda | 2021 |
Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance.
Topics: Adult; Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Chad; Female; Humans; Malaria, Falciparum; Pregnancy; Prospective Studies | 2023 |