ammonium hydroxide and glycerol phenylbutyrate

ammonium hydroxide has been researched along with glycerol phenylbutyrate in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's14 (82.35)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Beliveau, M; Diaz, GA; Dickinson, K; Feigenbaum, A; Jomphe, C; Lichter-Konecki, U; Marier, JF; Martinez, A; Mauney, J; Merritt, JL; Mokhtarani, M; Rhead, W; Scharschmidt, B1
Bart, S; Bartholomew, D; Bartley, J; Berquist, W; Berry, SA; Cederbaum, S; Coakley, DF; Diaz, GA; Dickinson, K; Dorrani, N; Feigenbaum, A; Gallagher, R; Harding, CO; Korson, MS; Kronn, D; Lee, B; Lemons, C; Lichter-Konecki, U; Longo, N; McCandless, SE; Merritt, JL; Mokhtarani, M; Moors, TL; Rhead, W; Scharschmidt, BF; Smith, W; Sreenath-Nagamani, S; Summar, M; Vockley, J; Zori, R1
Bart, SA; Bartholomew, D; Bartley, J; Berquist, W; Berry, SA; C S Nagamani, S; Cederbaum, S; Coakley, DF; Diaz, GA; Dickinson, K; Feigenbaum, A; Gallagher, R; Harding, CO; Korson, MS; Krivitzky, LS; Kronn, D; Lee, B; Lemons, C; Lichter-Konecki, U; Longo, N; Mauney, J; McCandless, SE; Merritt, JL; Mokhtarani, M; Moors, TL; Rhead, W; Scharschmidt, BF; Smith, W; Vockley, G; Zori, R1
Mistry, PK1
Berry, SA; Coakley, DF; Diaz, GA; Dickinson, K; Harding, CO; Lee, B; LeMons, C; Lichter-Konecki, U; Mauney, J; McCandless, SE; Mokhtarani, M; Moors, T; Scharschmidt, BF; Smith, W1
Alexeeva, O; Baranovsky, A; Bass, NM; Brown, RS; Coakley, D; Dickinson, K; Dudar, L; Fadieienko, G; Ghabril, M; Grewal, P; Grinevich, V; Kharchenko, N; Klaryts'ka, I; Mantry, P; McCashland, T; Mokhtarani, M; Morozov, V; Norris, C; Reddy, KG; Reddy, KR; Rockey, DC; Scharschmidt, BF; Syplyviy, V; Vierling, JM; Zupanets, IA1
Córdoba, J; Ventura-Cots, M1
Jalan, R; Jover-Cobos, M; Khetan, V1
Rahimi, RS; Rockey, DC1
Sussman, NL1
Bartley, J; Berquist, W; Berry, SA; Coakley, DF; Diaz, GA; Feigenbaum, A; Gallagher, RC; Harding, CO; Le Mons, C; Lee, B; Lichter-Konecki, U; Longo, N; Marino, M; McCandless, SE; Mokhtarani, M; Nagamani, SC; Rhead, W; Rowell, R; Scharschmidt, BF; Schulze, A; Smith, W1
Almannai, M; Elsea, SH; Jiang, Y; Sun, Q; Sutton, VR1
Berry, SA; Diaz, GA; Ficicioglu, C; Harding, CO; Lichter-Konecki, U; Longo, N; McCandless, SE; Robinson, B; Smith, WE; Vockley, J; Zori, R1
Alsahhar, JS; Rahimi, RS1
Alimirah, M; Gordon, SC; Sadiq, O1
Ah Mew, N; Bannick, AA; Berry, SA; Canavan, C; Conway, RL; Diaz, GA; Hainline, B; Inbar-Feigenberg, M; Kok, T; Lichter-Konecki, U; Longo, N; McCandless, SE; Porter, MH; Schulze, A; Vescio, T; Zori, R1
Daniotti, M; Donati, MA; Pochiero, F; Procopio, E; Sacchini, M; Scaturro, G1

Reviews

5 review(s) available for ammonium hydroxide and glycerol phenylbutyrate

ArticleYear
Treatment of hyperammonemia in liver failure.
    Current opinion in clinical nutrition and metabolic care, 2014, Volume: 17, Issue:1

    Topics: Ammonia; Brain; Glycerol; Hepatic Encephalopathy; Humans; Hyperammonemia; Lactulose; Phenylbutyrates; Probiotics; Randomized Controlled Trials as Topic; Rifamycins; Rifaximin

2014
Novel Ammonia-Lowering Agents for Hepatic Encephalopathy.
    Clinics in liver disease, 2015, Volume: 19, Issue:3

    Topics: Ammonia; Carbon; Gastrointestinal Agents; Glycerol; Hepatic Encephalopathy; Humans; Ornithine; Oxides; Phenylbutyrates; Polyethylene Glycols; Urea

2015
Treatment of Overt Hepatic Encephalopathy.
    Clinics in liver disease, 2015, Volume: 19, Issue:3

    Topics: Amino Acids, Branched-Chain; Ammonia; Arteriovenous Fistula; Dipeptides; Gastrointestinal Agents; Glycerol; Hepatic Encephalopathy; Humans; Lactulose; Liver Failure; Malnutrition; Ornithine; Phenylbutyrates; Probiotics; Rifamycins; Rifaximin

2015
Updates on the pathophysiology and therapeutic targets for hepatic encephalopathy.
    Current opinion in gastroenterology, 2019, Volume: 35, Issue:3

    Topics: Amino Acids, Aromatic; Amino Acids, Branched-Chain; Ammonia; Dipeptides; Fecal Microbiota Transplantation; Frailty; Gastrointestinal Agents; Gastrointestinal Microbiome; Glycerol; Hepatic Encephalopathy; Humans; Hypertension, Portal; Lactulose; Liver Cirrhosis; Ornithine; Phenylbutyrates; Polyethylene Glycols; Probiotics; Rifaximin; Trace Elements; Zinc

2019
Novel Therapies in Hepatic Encephalopathy.
    Clinics in liver disease, 2020, Volume: 24, Issue:2

    Topics: Acetylcarnitine; Albumins; Ammonia; Dipeptides; Fecal Microbiota Transplantation; Flumazenil; GABA Modulators; Glycerol; Hepatic Encephalopathy; Humans; Nootropic Agents; Ornithine; Phenylbutyrates; Polyethylene Glycols; Probiotics; Surface-Active Agents

2020

Trials

6 trial(s) available for ammonium hydroxide and glycerol phenylbutyrate

ArticleYear
Ammonia control in children with urea cycle disorders (UCDs); phase 2 comparison of sodium phenylbutyrate and glycerol phenylbutyrate.
    Molecular genetics and metabolism, 2011, Volume: 103, Issue:4

    Topics: Adolescent; Ammonia; Child; Dose-Response Relationship, Drug; Glycerol; Humans; Male; Phenylbutyrates; Urea; Urea Cycle Disorders, Inborn

2011
Urinary phenylacetylglutamine as dosing biomarker for patients with urea cycle disorders.
    Molecular genetics and metabolism, 2012, Volume: 107, Issue:3

    Topics: Adolescent; Adult; Ammonia; Biomarkers, Pharmacological; Child; Cross-Over Studies; Drug Administration Schedule; Female; Glutamine; Glycerol; Humans; Male; Phenylacetates; Phenylbutyrates; Urea Cycle Disorders, Inborn

2012
Ammonia control and neurocognitive outcome among urea cycle disorder patients treated with glycerol phenylbutyrate.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:6

    Topics: Adolescent; Adult; Ammonia; Child; Cross-Over Studies; Double-Blind Method; Female; Glutamine; Glycerol; Humans; Male; Middle Aged; Neuropsychological Tests; Phenylbutyrates; Urea Cycle Disorders, Inborn; Young Adult

2013
Ammonia control in children ages 2 months through 5 years with urea cycle disorders: comparison of sodium phenylbutyrate and glycerol phenylbutyrate.
    The Journal of pediatrics, 2013, Volume: 162, Issue:6

    Topics: Ammonia; Child; Child, Preschool; Drug Substitution; Female; Glutamine; Glycerol; Humans; Infant; Liver; Male; Phenylbutyrates; Surveys and Questionnaires; Urea Cycle Disorders, Inborn

2013
Randomized, double-blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:3

    Topics: Adult; Aged; Ammonia; Double-Blind Method; Female; Glutamine; Glycerol; Hepatic Encephalopathy; Humans; Hyperammonemia; Male; Middle Aged; Phenylbutyrates; Treatment Outcome; Urea; Young Adult

2014
Glutamine and hyperammonemic crises in patients with urea cycle disorders.
    Molecular genetics and metabolism, 2016, Volume: 117, Issue:1

    Topics: Adolescent; Adult; Ammonia; Biomarkers; Child; Child, Preschool; Fasting; Female; Glutamine; Glycerol; Humans; Hyperammonemia; Male; Phenylbutyrates; Predictive Value of Tests; Urea Cycle Disorders, Inborn; Young Adult

2016

Other Studies

6 other study(ies) available for ammonium hydroxide and glycerol phenylbutyrate

ArticleYear
Rare disease clinical research network's urea cycle consortium delivers a successful clinical trial to improve alternate pathway therapy.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:6

    Topics: Ammonia; Female; Glycerol; Humans; Male; Phenylbutyrates; Urea Cycle Disorders, Inborn

2013
Drug-induced removal of nitrogen derivatives in urine: a new concept whose time has come.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:3

    Topics: Ammonia; Female; Glycerol; Hepatic Encephalopathy; Humans; Hyperammonemia; Male; Phenylbutyrates

2014
Quantitation of phenylbutyrate metabolites by UPLC-MS/MS demonstrates inverse correlation of phenylacetate:phenylacetylglutamine ratio with plasma glutamine levels.
    Molecular genetics and metabolism, 2017, Volume: 122, Issue:3

    Topics: Ammonia; Argininosuccinic Aciduria; Chromatography, Liquid; Female; Glutamine; Glycerol; Humans; Limit of Detection; Male; Middle Aged; Ornithine Carbamoyltransferase Deficiency Disease; Phenylacetates; Phenylbutyrates; Tandem Mass Spectrometry; Urea; Urea Cycle Disorders, Inborn

2017
Safety and efficacy of glycerol phenylbutyrate for management of urea cycle disorders in patients aged 2months to 2years.
    Molecular genetics and metabolism, 2017, Volume: 122, Issue:3

    Topics: Ammonia; Child, Preschool; Cough; Disease Management; Drug-Related Side Effects and Adverse Reactions; Female; Fever; Glutamine; Glycerol; Humans; Infant; Male; Neutropenia; Phenylbutyrates; Prospective Studies; Retrospective Studies; Urea Cycle Disorders, Inborn

2017
Glycerol phenylbutyrate efficacy and safety from an open label study in pediatric patients under 2 months of age with urea cycle disorders.
    Molecular genetics and metabolism, 2021, Volume: 132, Issue:1

    Topics: Age of Onset; Ammonia; Child, Preschool; Female; Glycerol; Humans; Hyperammonemia; Infant; Infant, Newborn; Male; Pediatrics; Phenylacetates; Phenylbutyrates; Renal Dialysis; Urea Cycle Disorders, Inborn

2021
Transition to glycerol phenylbutyrate for the management of urea cycle disorders: clinical experiences.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:22

    Topics: Ammonia; Glutamine; Humans; Quality of Life; Urea; Urea Cycle Disorders, Inborn

2023