ammonium hydroxide has been researched along with 4-phenylbutyric acid in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Beliveau, M; Berry, SA; Diaz, GA; Dickinson, K; Gargosky, S; Lee, B; Marier, JF; Martinez, A; Mauney, J; Mian, A; Mokhtarani, M; Rhead, W; Scharschmidt, BF; Shchelochkov, O | 1 |
| Beliveau, M; Diaz, GA; Dickinson, K; Feigenbaum, A; Jomphe, C; Lichter-Konecki, U; Marier, JF; Martinez, A; Mauney, J; Merritt, JL; Mokhtarani, M; Rhead, W; Scharschmidt, B | 1 |
| Bart, SA; Bartholomew, D; Bartley, J; Berquist, W; Berry, SA; C S Nagamani, S; Cederbaum, S; Coakley, DF; Diaz, GA; Dickinson, K; Feigenbaum, A; Gallagher, R; Harding, CO; Korson, MS; Krivitzky, LS; Kronn, D; Lee, B; Lemons, C; Lichter-Konecki, U; Longo, N; Mauney, J; McCandless, SE; Merritt, JL; Mokhtarani, M; Moors, TL; Rhead, W; Scharschmidt, BF; Smith, W; Vockley, G; Zori, R | 1 |
| Mistry, PK | 1 |
| Berry, SA; Coakley, DF; Diaz, GA; Dickinson, K; Harding, CO; Lee, B; LeMons, C; Lichter-Konecki, U; Mauney, J; McCandless, SE; Mokhtarani, M; Moors, T; Scharschmidt, BF; Smith, W | 1 |
| Irie, T; Irikura, M; Ishitsuka, Y; Iwawaki, T; Kondo, Y; Miyata, K; Oike, Y; Shimizu, D; Tomishima, Y | 1 |
| Chang, L; Wang, D; Wang, Y; Wu, Q; Zhai, J | 1 |
| Brisson, H; Guiller, E; Imbert-Bismut, F; Junot, H; Lodey, M; Mallet, M; Mayaux, J; Monneret, D; Rudler, M; Thabut, D; Tripon, S; Weiss, N | 1 |
| Finnegan, J; Giva, S; Ihidero, P; Knerr, I; Maguire, G; Monavari, A; Power, B | 1 |
| Favier, RP; Mesu, SJ; Rothuizen, J; Spee, B; Teske, E; van Dalen, D; van Geijlswijk, IM; van Straten, G | 1 |
| Hasegawa, T; Ishii, T; Kato, M; Kuroda, T; Nakatsuka, S; Oyanagi, T; Sato, T | 1 |
| Djernes, L; Eriksen, PL; Ott, P; Vilstrup, H | 1 |
| Altintas, B; Eldem, I; Langley, R; Lee, A; Nguyen, H; Shinawi, M; Willis, D | 1 |
| Cheng, Y; Huang, X; Qiao, Y; Shang, X; Yu, Z; Zhou, D | 1 |
1 review(s) available for ammonium hydroxide and 4-phenylbutyric acid
| Article | Year |
|---|---|
[Preliminary study of glyceryl phenylbutyrate therapy for Ornithine transcarbamylase deficiency and a literature review].
Topics: Ammonia; Child; Humans; Ornithine Carbamoyltransferase Deficiency Disease; Phenylbutyrates; Retrospective Studies | 2023 |
6 trial(s) available for ammonium hydroxide and 4-phenylbutyric acid
| Article | Year |
|---|---|
Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: safety, pharmacokinetics and ammonia control.
Topics: Adult; Aged; Ammonia; Cross-Over Studies; Female; Glutamine; Glycerol; Humans; Male; Middle Aged; Phenylacetates; Phenylbutyrates; Urea Cycle Disorders, Inborn; Young Adult | 2010 |
Ammonia control in children with urea cycle disorders (UCDs); phase 2 comparison of sodium phenylbutyrate and glycerol phenylbutyrate.
Topics: Adolescent; Ammonia; Child; Dose-Response Relationship, Drug; Glycerol; Humans; Male; Phenylbutyrates; Urea; Urea Cycle Disorders, Inborn | 2011 |
Ammonia control and neurocognitive outcome among urea cycle disorder patients treated with glycerol phenylbutyrate.
Topics: Adolescent; Adult; Ammonia; Child; Cross-Over Studies; Double-Blind Method; Female; Glutamine; Glycerol; Humans; Male; Middle Aged; Neuropsychological Tests; Phenylbutyrates; Urea Cycle Disorders, Inborn; Young Adult | 2013 |
Ammonia control in children ages 2 months through 5 years with urea cycle disorders: comparison of sodium phenylbutyrate and glycerol phenylbutyrate.
Topics: Ammonia; Child; Child, Preschool; Drug Substitution; Female; Glutamine; Glycerol; Humans; Infant; Liver; Male; Phenylbutyrates; Surveys and Questionnaires; Urea Cycle Disorders, Inborn | 2013 |
Efficacy of orally administered sodium benzoate and sodium phenylbutyrate in dogs with congenital portosystemic shunts.
Topics: Ammonia; Animals; Bile Acids and Salts; Cross-Over Studies; Dogs; Double-Blind Method; Female; Hyperammonemia; Male; Phenylbutyrates; Portal Vein; Random Allocation; Sodium Benzoate; Vascular Malformations | 2019 |
Clearance and production of ammonia quantified in humans by constant ammonia infusion - the effects of cirrhosis and ammonia-targeting treatments.
Topics: Ammonia; Hepatic Encephalopathy; Humans; Hyperammonemia; Lactulose; Liver Cirrhosis; Male; Phenylbutyrates; Rifaximin | 2023 |
7 other study(ies) available for ammonium hydroxide and 4-phenylbutyric acid
| Article | Year |
|---|---|
Rare disease clinical research network's urea cycle consortium delivers a successful clinical trial to improve alternate pathway therapy.
Topics: Ammonia; Female; Glycerol; Humans; Male; Phenylbutyrates; Urea Cycle Disorders, Inborn | 2013 |
Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice.
Topics: Acetaminophen; Alanine Transaminase; Ammonia; Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; DNA Fragmentation; DNA-Binding Proteins; Glutathione; Liver; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Transgenic; Phenylbutyrates; Protective Agents; Proto-Oncogene Proteins; Regulatory Factor X Transcription Factors; Transcription Factor CHOP; Transcription Factors; Tyrosine; X-Box Binding Protein 1 | 2014 |
Generation of carbamoyl phosphate synthetase 1 reporter cell lines for the assessment of ammonia metabolism.
Topics: Albumins; Ammonia; Carbamoyl-Phosphate Synthase (Ammonia); CCAAT-Enhancer-Binding Proteins; Cell Line, Transformed; CRISPR-Cas Systems; Cytochrome P-450 Enzyme System; Founder Effect; Gene Editing; Gene Expression Regulation; Genes, Reporter; Hep G2 Cells; Hepatocyte Nuclear Factor 4; High-Throughput Screening Assays; Humans; Inactivation, Metabolic; Liver, Artificial; Luminescent Proteins; Phenylbutyrates; Red Fluorescent Protein; Resveratrol; Small Molecule Libraries; Stilbenes; Urea | 2017 |
Treating hepatic encephalopathy in cirrhotic patients admitted to ICU with sodium phenylbutyrate: a preliminary study.
Topics: Aged; Ammonia; Biomarkers; Case-Control Studies; Female; Hepatic Encephalopathy; Hospital Mortality; Humans; Hyperammonemia; Intensive Care Units; Liver Cirrhosis; Male; Middle Aged; Patient Admission; Patient Discharge; Phenylbutyrates; Preliminary Data; Prospective Studies; Time Factors; Treatment Outcome | 2018 |
Hyperammonaemia in Neonates and Young Children: Potential Metabolic Causes, Diagnostic Approaches and Clinical Consequences
Topics: Ammonia; Arginine; Biomarkers; Brain Diseases, Metabolic, Inborn; Carnitine; Critical Illness; Diet, Protein-Restricted; Early Diagnosis; Emergencies; Female; Humans; Hyperammonemia; Infant; Infant, Newborn; Male; Phenylbutyrates; Sodium Benzoate; Treatment Outcome | 2019 |
Oral sodium phenylbutyrate for hyperammonemia associated with congenital portosystemic shunt: a case report.
Topics: Administration, Oral; Amino Acids, Branched-Chain; Ammonia; Humans; Hyperammonemia; Infant; Male; Phenylbutyrates; Portal System; Portal Vein | 2021 |
Treatment and outcomes of symptomatic hyperammonemia following asparaginase therapy in children with acute lymphoblastic leukemia.
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Child; Glutamine; Humans; Hyperammonemia; Phenylbutyrates; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sodium Benzoate; Treatment Outcome | 2023 |