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ammonium chloride and leupeptins

ammonium chloride has been researched along with leupeptins in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199032 (43.84)18.7374
1990's26 (35.62)18.2507
2000's7 (9.59)29.6817
2010's8 (10.96)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morton, PA; Owensby, DA; Schwartz, AL; Underhill, DM1
Banerjee, D; Grieninger, G; Mukhopadhyay, G; Oddoux, C; Overton, O; Redman, C; Roy, S; Yu, S1
Ramanujam, KS; Seetharam, B; Seetharam, S1
Estus, S; Golde, TE; Selkoe, DJ; Younkin, LH; Younkin, SG1
Anderson, SK; Geissler, F; Press, O1
Ginsburg, H; Krugliak, M1
Mercer, JR; Silva, SV1
Danno, K; Hirayoshi, K; Hosokawa, M; Imamura, S; Miyachi, Y; Nagata, K; Nishigori, C; Takeda, T; Tanaka, T; Utani, A1
Clem, LW; Jørgensen, T; Miller, NW; Vallejo, AN1
Barile, FA; Bienkowski, RS; Guzowski, DE; Ripley, C; Siddiqi, ZA1
Banker, DE; Gottesman, MM; Herschman, HR; Pastan, I1
Moss, AL; Ward, WF1
Bland, PW; Whiting, CV1
Ballard, FJ; Hopgood, MF; Knowles, SE1
Maeda, M; Neda, H; Niitsu, Y; Sone, H; Urushizaki, I; Watanabe, N; Yamauchi, N1
Presky, DH; Schonbrunn, A1
Billett, EE; Earl, RT; Hunneyball, IM; Mayer, RJ1
Alvarez-Azaustre, E; Hamilton, RT; Jang, YJ; Nilsen-Hamilton, M1
Bauer, A; Kirchner, H; Rutenfranz, I1
Hoppe, W; Kresse, H; Rauch, U1
Aniento, F; Grisolía, S; Knecht, E; Roche, E; Vargas, JL1
Capony, F; Morisset, M; Rochefort, H1
Endo, N; Hara, T; Kato, Y; Kishida, K; Saito, M; Takeda, Y; Umemoto, N1
Ascoli, M; Segaloff, DL1
Ballard, FJ1
Kooistra, T; Lloyd, JB1
Oude Elferink, RP; Reuser, AJ; Strijland, A; Tager, JM; Van Doorn-Van Wakeren, J1
Andersen, KB1
Billiar, RB; Hossner, KL1
Berg, T; Carlander, B; Drevon, CA; Tolleshaug, H1
Ascoli, M1
Berkower, IJ; Berzofsky, JA; Busch, M; Gurd, FR; Streicher, HZ1
Bystryn, JC; Johnston, D1
Cockle, SM; Dean, RT2
Ibbotson, GE; Livesey, G; Weisbecker, U; Williams, KE1
Ando, M; Furuno, K; Kato, K; Kuwano, M; Ono, M; Shimada, T1
Amenta, JS; Mayer, RJ; Russell, SM1
Goodman, HM; Gorin, E; Grichting, G1
Bourrie, BJ; Casellas, P; Gros, P; Jansen, FK1
Oikawa, A; Saeki, H1
Aulinskas, TH; Coetzee, GA; van der Westhuyzen, DR1
Bunnett, NW; Garland, AM; Grady, EF; Payan, DG; Vigna, SR1
Esko, JD; Hager, KM; Hajduk, SL; Moore, DR; Pierce, MA; Tytler, EM1
Goldenberg, DM; Lu, HH; Shih, LB; Xuan, H1
Evans, PJ1
Haass, C; Hung, AY; Oltersdorf, T; Schlossmacher, MG; Selkoe, DJ; Teplow, DB1
Haass, C; Hung, AY; Schlossmacher, MG; Selkoe, DJ; Teplow, DB1
Loss, GE; Sant, AJ1
Getz, GS; Reardon, CA; Ye, SQ1
Lodish, HF; Neumann, D; Watowich, SS; Wikström, L1
Hirai, S; Iizuka, T; Kasai, K; Kawarabayashi, T; Kobayashi, T; Matsubara, E; Sato, M; Shoji, M; Tada, N; Tomidokoro, Y; Watanabe, M1
Davis, EC; Mecham, RP1
Hirano, K; Masuda, K; Nagata, S; Nogusa, H; Takagishi, Y1
Baccino, FM; Codogno, P; De Stefanis, D; Démoz, M; Dragonetti, A; Houri, JJ; Isidoro, C; Ogier-Denis, E1
Beyer, EC; Green, K; Laing, JG; Saffitz, JE; Tadros, PN1
Asakura, T; Hashizume, Y; Ohkawa, K; Okawa, Y; Sawai, T; Takada, K; Yanaihara, N1
Friedmann, JM; Thévenod, F1
Bang, KW; Blanchette, VS; Freedman, J; Semple, JW; Speck, ER1
Duthie, M; Fraser, PE; Holmes, E; Martins, RN; St George-Hyslop, PH; Verdile, G1
Fuska, J; Lefrancois, S; Morales, CR; Zhao, Q1
Blystad, FD; Johannessen, LE; Larsen, AM; Longva, KE; Madshus, IH; Stang, E1
Correia, MA; Faouzi, S; Hefner, C; Maher, JJ; Medzihradszky, KF1
de Boer, TP; Jansen, JA; van der Heyden, MA; van Rijen, HV; van Veen, TA; Vos, MA; Wolswinkel, R1
Jia, L; Wang, MM; Yu, G; Zhang, Y1
Ahn, JS; Ann, EJ; Choi, YH; Hoe, HS; Jung, J; Kim, H; Kim, HY; Kim, K; Kim, MY; Kim, SM; Mo, JS; Park, HS; Yoon, JH1
Ann, EJ; Kim, MY; Kim, SM; Mo, JS; Park, HS; Yoon, JH1
Kitanaka, A; Kubota, Y; Ohara-Waki, F; Shintani, T; Tanaka, T1
Baccarini, S; Cagnin, M; De Luca, G; Dogliotti, E; Falchi, M; Ferretti, C; Fortini, P; Garribba, L; Iorio, E; Isidoro, C; Morani, F; Pascucci, B; Phadngam, S; Pietraforte, D1
Choudhary, AK; Dey, CS1
de la Torre, JC; Iwasaki, M1
Cuervo, AM; Juste, YR1
Ding, H; Guo, J; Ji, Y; Jiao, J; Lv, Z; Wang, H1

Other Studies

73 other study(ies) available for ammonium chloride and leupeptins

ArticleYear
Endocytosis and lysosomal delivery of tissue plasminogen activator-inhibitor 1 complexes in Hep G2 cells.
    Blood, 1992, Dec-01, Volume: 80, Issue:11

    Topics: Ammonium Chloride; beta-N-Acetylhexosaminidases; Carcinoma, Hepatocellular; Chloroquine; Endocytosis; Humans; Kinetics; Leupeptins; Liver Neoplasms; Lysosomes; Pepstatins; Plasminogen Activator Inhibitor 1; Primaquine; Recombinant Proteins; Subcellular Fractions; Tissue Plasminogen Activator; Tumor Cells, Cultured

1992
Assembly and secretion of fibrinogen. Degradation of individual chains.
    The Journal of biological chemistry, 1992, Nov-15, Volume: 267, Issue:32

    Topics: Ammonium Chloride; Animals; Cell Line; Chickens; Chloroquine; Fibrinogen; Humans; Kinetics; Leupeptins; Liver; Lysosomes; Macromolecular Substances; Methionine; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured

1992
Leupeptin and ammonium chloride inhibit intrinsic factor mediated transcytosis of [57Co]cobalamin across polarized renal epithelial cells.
    Biochemical and biophysical research communications, 1992, Jan-31, Volume: 182, Issue:2

    Topics: Ammonium Chloride; Animals; Autoradiography; Biological Transport; Cells, Cultured; Chromatography, Gel; Cobalt Radioisotopes; Electrophoresis, Polyacrylamide Gel; Epithelium; Intrinsic Factor; Iodine Radioisotopes; Kidney; Leupeptins; Molecular Weight; Opossums; Rats; Vitamin B 12

1992
Processing of the amyloid protein precursor to potentially amyloidogenic derivatives.
    Science (New York, N.Y.), 1992, Feb-07, Volume: 255, Issue:5045

    Topics: Ammonium Chloride; Amyloid; Amyloid beta-Protein Precursor; Base Sequence; Cell Line; Endopeptidases; Humans; Leupeptins; Lysosomes; Molecular Sequence Data; Mutagenesis; Peptide Fragments; Transfection

1992
Intracellular catabolism of radiolabeled anti-CD3 antibodies by leukemic T cells.
    Cellular immunology, 1991, Oct-01, Volume: 137, Issue:1

    Topics: Ammonium Chloride; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Autoradiography; CD3 Complex; Endocytosis; Humans; In Vitro Techniques; Leukemia-Lymphoma, Adult T-Cell; Leupeptins; Molecular Weight; Monensin; Peptide Fragments; Receptors, Antigen, T-Cell; T-Lymphocytes; Tumor Cells, Cultured

1991
Studies on the antimalarial mode of action of quinoline-containing drugs: time-dependence and irreversibility of drug action, and interactions with compounds that alter the function of the parasite's food vacuole.
    Life sciences, 1991, Volume: 49, Issue:17

    Topics: Ammonium Chloride; Animals; Antimalarials; Drug Combinations; Drug Interactions; Hydrogen-Ion Concentration; Leupeptins; Plasmodium falciparum; Quinolines; Time Factors

1991
The effect of lysosomal inhibitors on protein degradation in cat hepatocyte monolayers.
    The International journal of biochemistry, 1991, Volume: 23, Issue:5-6

    Topics: Ammonium Chloride; Animals; Cats; Cells, Cultured; Cycloheximide; Insulin; Leucine; Leupeptins; Liver; Lysosomes; Proteins

1991
Another mechanism for the defect in type III collagen accumulation in Ehlers-Danlos syndrome type IV: increased intracellular degradation of the procollagen.
    Laboratory investigation; a journal of technical methods and pathology, 1990, Volume: 63, Issue:2

    Topics: Ammonium Chloride; Biological Transport; Blotting, Southern; Cells, Cultured; Collagen; Ehlers-Danlos Syndrome; Extracellular Space; Fluorescent Antibody Technique; Glycosylation; In Vitro Techniques; Leupeptins; Lysosomes; Peptide Fragments; Procollagen; Skin

1990
Phylogeny of immune recognition: antigen processing/presentation in channel catfish immune responses to hemocyanins.
    Cellular immunology, 1990, Oct-15, Volume: 130, Issue:2

    Topics: Ammonium Chloride; Animals; Antibody Formation; Antigen-Presenting Cells; Antigens; B-Lymphocytes; Chloroquine; Fixatives; Hemocyanins; Ictaluridae; In Vitro Techniques; Leupeptins; Lymphocyte Activation; Monensin; Monocytes; Phenylmethylsulfonyl Fluoride

1990
Ammonium chloride inhibits basal degradation of newly synthesized collagen in human fetal lung fibroblasts.
    Archives of biochemistry and biophysics, 1990, Volume: 276, Issue:1

    Topics: Adenosine Triphosphate; Ammonium Chloride; Cells, Cultured; Collagen; Fetus; Fibroblasts; Humans; Kinetics; Leupeptins; Lung; Tosyllysine Chloromethyl Ketone

1990
An epidermal growth factor-ricin A chain (EGF-RTA)-resistant mutant and an epidermal growth factor-Pseudomonas endotoxin (EGF-PE)-resistant mutant have distinct phenotypes.
    Journal of cellular physiology, 1989, Volume: 139, Issue:1

    Topics: Adenoviridae; ADP Ribose Transferases; Ammonium Chloride; Bacterial Toxins; Drug Resistance; Epidermal Growth Factor; Exotoxins; HeLa Cells; Humans; Immunotoxins; Leupeptins; Mutation; Phenotype; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Ricin; Virulence Factors

1989
Effects of lysosomal inhibitors on 125I-insulin and 125I-asialofetuin degradation by the isolated, perfused rat liver and isolated rat hepatocytes.
    Diabetes, 1985, Volume: 34, Issue:5

    Topics: alpha-Fetoproteins; Ammonium Chloride; Animals; Asialoglycoproteins; Chloroquine; Fetuins; In Vitro Techniques; Insulin; Iodine Radioisotopes; Leupeptins; Liver; Lysosomes; Male; Perfusion; Rats; Rats, Inbred Strains

1985
Antigen processing by isolated rat intestinal villus enterocytes.
    Immunology, 1989, Volume: 68, Issue:4

    Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Cell Separation; Chloroquine; Intestinal Mucosa; Leupeptins; Lysosomes; Microvilli; Monensin; Ovalbumin; Rats

1989
Effects of inhibitors on aldolase breakdown after its microinjection into HeLa cells.
    The Biochemical journal, 1989, Apr-01, Volume: 259, Issue:1

    Topics: Adenine; Ammonium Chloride; Ethylmaleimide; Fructose-Bisphosphate Aldolase; HeLa Cells; Humans; Insulin; Leupeptins; Microinjections

1989
Cytocidal mechanism of TNF: effects of lysosomal enzyme and hydroxyl radical inhibitors on cytotoxicity.
    Immunopharmacology and immunotoxicology, 1988, Volume: 10, Issue:1

    Topics: Ammonium Chloride; Animals; Chloroquine; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Free Radicals; Hydroxides; Hydroxyl Radical; Leupeptins; Masoprocol; Methylamines; Mice; Muramidase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1988
Receptor-bound somatostatin and epidermal growth factor are processed differently in GH4C1 rat pituitary cells.
    The Journal of cell biology, 1986, Volume: 102, Issue:3

    Topics: Ammonium Chloride; Animals; Cell Compartmentation; Cell Line; Cell Membrane; Chloroquine; Cytosol; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Leupeptins; Lysosomes; Pituitary Neoplasms; Protein Binding; Rats; Receptors, Cell Surface; Receptors, Somatostatin; Somatostatin

1986
Sendai-viral HN and F glycoproteins as probes of plasma-membrane protein catabolism in HTC cells. Studies with fusogenic reconstituted Sendai-viral envelopes.
    The Biochemical journal, 1987, Feb-01, Volume: 241, Issue:3

    Topics: Ammonium Chloride; Animals; Azides; Cell Line; Deoxyglucose; DNA, Viral; Hemagglutinins, Viral; HN Protein; Leupeptins; Liver Neoplasms, Experimental; Membrane Fusion; Membrane Proteins; Parainfluenza Virus 1, Human; Sodium Azide; Viral Envelope Proteins; Viral Fusion Proteins

1987
Regulation of the production of a prolactin-like protein (MRP/PLF) in 3T3 cells and in the mouse placenta.
    Molecular and cellular endocrinology, 1988, Volume: 56, Issue:3

    Topics: Ammonium Chloride; Animals; Antipain; Cell Line; Epidermal Growth Factor; Fibroblast Growth Factors; Glycoproteins; Glycosylation; Intercellular Signaling Peptides and Proteins; Kinetics; Leupeptins; Mice; Monensin; Placenta; Prolactin; RNA, Messenger

1988
Processing requirements for T cell activation by Mycoplasma arthritidis-derived mitogen.
    European journal of immunology, 1988, Volume: 18, Issue:12

    Topics: Ammonium Chloride; Antigen-Presenting Cells; Chloroquine; Formaldehyde; Leupeptins; Lymphocyte Activation; Lysosomes; Macrophages; Mitogens; Monensin; Mycoplasma; Polymers; T-Lymphocytes

1988
Degradation of endocytosed dermatan sulfate proteoglycan in human fibroblasts.
    The Journal of biological chemistry, 1988, Apr-25, Volume: 263, Issue:12

    Topics: Ammonium Chloride; Biological Transport; Cells, Cultured; Chondroitin; Chondroitin Sulfate Proteoglycans; Cycloheximide; Dermatan Sulfate; Diazomethane; Endocytosis; Fibroblasts; Half-Life; Humans; Kinetics; Leucine; Leupeptins; Lysosomes; Molecular Weight; Protease Inhibitors; Proteoglycans; Sulfates

1988
The mitochondrial probe rhodamine 123 inhibits in isolated hepatocytes the degradation of short-lived proteins.
    FEBS letters, 1988, Jun-20, Volume: 233, Issue:2

    Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Cells, Cultured; Fluorescent Dyes; Kinetics; Leupeptins; Liver; Male; Mitochondria, Liver; Proteins; Rats; Rats, Inbred Strains; Reference Values; Rhodamine 123; Rhodamines; Xanthenes

1988
Processing and estrogen regulation of the 52-kilodalton protein inside MCF7 breast cancer cells.
    Endocrinology, 1986, Volume: 119, Issue:6

    Topics: Ammonium Chloride; Antibodies, Monoclonal; Breast Neoplasms; Cell Compartmentation; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation; Glycosylation; Humans; Leupeptins; Molecular Weight; Monensin; Neoplasm Proteins; Protein Processing, Post-Translational

1986
In vitro cytotoxicity of a human serum albumin-mediated conjugate of methotrexate with anti-MM46 monoclonal antibody.
    Cancer research, 1987, Feb-15, Volume: 47, Issue:4

    Topics: Ammonium Chloride; Animals; Antibodies, Monoclonal; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry, Physical; Cytotoxicity, Immunologic; Leupeptins; Methotrexate; Mice; Mice, Inbred C3H; Serum Albumin

1987
On the fates of receptor-bound ovine luteinizing hormone and human chorionic gonadotropin in cultured Leydig tumor cells. Demonstration of similar rates of internalization.
    Endocrinology, 1987, Volume: 120, Issue:3

    Topics: Ammonium Chloride; Animals; Biological Transport; Chorionic Gonadotropin; Endocytosis; Kinetics; Leupeptins; Leydig Cell Tumor; Luteinizing Hormone; Male; Mice; Receptors, LH; Sheep; Sodium

1987
Regulation of protein breakdown by epidermal growth factor in A431 cells.
    Experimental cell research, 1985, Volume: 157, Issue:1

    Topics: Adenine; Ammonium Chloride; Autolysis; Carcinoma, Squamous Cell; Cell Line; Cycloheximide; Epidermal Growth Factor; Fibroblasts; Humans; Hydrogen-Ion Concentration; Insulin; Leupeptins; Lung; Proteins; Time Factors; Vinblastine

1985
Degradation of insulin by human fibroblasts: effects of inhibitors of pinocytosis and lysosomal activity.
    The International journal of biochemistry, 1985, Volume: 17, Issue:7

    Topics: 2,4-Dinitrophenol; Ammonium Chloride; Anti-Bacterial Agents; Biological Transport; Cells, Cultured; Dinitrophenols; Fibroblasts; Humans; Insulin; Iodine Radioisotopes; Kinetics; Leupeptins; Lysosomes; Pinocytosis; Povidone-Iodine; Skin; Sodium Fluoride

1985
Biosynthesis and intracellular transport of alpha-glucosidase and cathepsin D in normal and mutant human fibroblasts.
    European journal of biochemistry, 1985, Nov-15, Volume: 153, Issue:1

    Topics: alpha-Glucosidases; Ammonium Chloride; Biological Transport; Cathepsin D; Cell Line; Centrifugation, Density Gradient; Dipeptides; Fibroblasts; Glucosidases; Humans; Immunochemistry; Leupeptins; Lysosomes; Mutation; Organoids; Skin

1985
The fate of the surface protein gp70 during entry of retrovirus into mouse fibroblasts.
    Virology, 1985, Apr-15, Volume: 142, Issue:1

    Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glucosamine; Kinetics; Leucine; Leupeptins; Mice; Retroviridae; Retroviridae Proteins; Tritium; Viral Envelope Proteins

1985
Metabolism of asialotranscortin by hepatocytes and cortisol binding to hepatocytes.
    Endocrine research communications, 1981, Volume: 8, Issue:2

    Topics: alpha-Fetoproteins; Ammonium Chloride; Animals; Asialoglycoproteins; Dose-Response Relationship, Drug; Female; Fetuins; Hydrocortisone; Leupeptins; Liver; Male; Rats; Rats, Inbred Strains; Transcortin

1981
Metabolism of asialoglycoproteins in cultured rat hepatocytes: evidence for receptor mediated uptake and degradation which is not feed-back regulated.
    The International journal of biochemistry, 1983, Volume: 15, Issue:6

    Topics: alpha-Fetoproteins; Ammonium Chloride; Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Cells, Cultured; Chloroquine; Cycloheximide; Fetuins; Leupeptins; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface

1983
Receptor-mediated uptake and degradation of human chorionic gonadotropin: fate of the hormone subunits.
    Annals of the New York Academy of Sciences, 1982, Volume: 383

    Topics: Ammonium Chloride; Chorionic Gonadotropin; Clone Cells; Endocytosis; Humans; Hydrogen-Ion Concentration; Kinetics; Leupeptins; Leydig Cell Tumor; Lysosomes; Male; Models, Biological; Monoiodotyrosine; Receptors, Cell Surface; Receptors, LH; Temperature; Testicular Neoplasms

1982
Antigen conformation determines processing requirements for T-cell activation.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:21

    Topics: Ammonium Chloride; Animals; Antigens; Chloroquine; Clone Cells; Leupeptins; Lymphocyte Activation; Lysosomes; Mice; Monensin; Myoglobin; Peptide Fragments; Protein Conformation; Protein Denaturation; Structure-Activity Relationship; T-Lymphocytes

1984
Mechanism of autodegradation of cell-surface macromolecules shed by human melanoma cells.
    Experimental cell research, 1984, Volume: 152, Issue:1

    Topics: Ammonium Chloride; Biological Transport; Cadaverine; Cell Line; Chloroquine; Coated Pits, Cell-Membrane; Colchicine; Cytochalasin B; Endocytosis; Humans; Leupeptins; Lysosomes; Melanoma; Membrane Proteins; Monensin; Neoplasm Proteins; Time Factors; Tunicamycin

1984
An abnormality in intracellular protein degradation in fibroblasts from patients with I-cell disease.
    Clinica chimica acta; international journal of clinical chemistry, 1984, Jul-31, Volume: 140, Issue:3

    Topics: Ammonium Chloride; Cytosol; Fibroblasts; Half-Life; Humans; Leupeptins; Lysosomes; Mucolipidoses; Pepstatins; Proteins

1984
The fate of homologous 125I-labelled immunoglobulin G within rat visceral yolk sacs incubated in vitro.
    The Biochemical journal, 1983, Sep-15, Volume: 214, Issue:3

    Topics: 2,4-Dinitrophenol; Ammonium Chloride; Animals; Dinitrophenols; Female; Immunoglobulin G; In Vitro Techniques; Iodine Radioisotopes; Leupeptins; Povidone; Pregnancy; Rats; Rotenone; Serum Albumin, Bovine; Yolk Sac

1983
Isolation of chloroquine-resistant Chinese hamster V79 cell variants that are also resistant to ammonium chloride.
    Journal of biochemistry, 1983, Volume: 94, Issue:5

    Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Clone Cells; Cricetinae; Cricetulus; Drug Resistance; Leupeptins; Lysosomes; Mutation; Phenotype; Proteins

1983
Degradation of proteins in rat liver mitochondrial outer membrane transplanted into different cell types. Evidence for alternative processing.
    The Biochemical journal, 1984, Jun-01, Volume: 220, Issue:2

    Topics: Ammonium Chloride; Animals; Cell Line; Cricetinae; Cycloheximide; Half-Life; Humans; Intracellular Membranes; Leucine; Leupeptins; Liver Neoplasms, Experimental; Membrane Proteins; Mice; Microscopy, Fluorescence; Mitochondria, Liver; Rats

1984
Binding and degradation of [125I]human growth hormone in rat adipocytes.
    Endocrinology, 1984, Volume: 115, Issue:2

    Topics: Adipose Tissue; Ammonium Chloride; Animals; Chloroquine; Colchicine; Growth Hormone; Humans; Iodine Radioisotopes; Leupeptins; Rats; Rats, Inbred Strains; Temperature; Time Factors

1984
Kinetics of cytotoxicity induced by immunotoxins. Enhancement by lysosomotropic amines and carboxylic ionophores.
    The Journal of biological chemistry, 1984, Aug-10, Volume: 259, Issue:15

    Topics: Amines; Ammonium Chloride; Animals; Antigens, Surface; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Humans; Ionophores; Isoantibodies; Kinetics; Leukemia, Experimental; Leupeptins; Mice; Monensin; Nigericin; Pepstatins; Protein Biosynthesis; Ricin

1984
Synthesis and degradation of tyrosinase in cultured melanoma cells.
    Journal of cellular physiology, 1980, Volume: 104, Issue:2

    Topics: Ammonium Chloride; Animals; Catechol Oxidase; Cell Line; Culture Media; Galactose; Glucose; Hydrogen-Ion Concentration; Kinetics; Leupeptins; Melanoma; Mice; Monophenol Monooxygenase

1980
The regulation of proteolysis in normal fibroblasts as they approach confluence. Evidence for the participation of the lysosomal system.
    The Biochemical journal, 1982, Dec-15, Volume: 208, Issue:3

    Topics: Ammonium Chloride; Animals; Cells, Cultured; Diazomethane; Fibroblasts; Humans; Leupeptins; Lysosomes; Mice; Pepstatins; Proteins

1982
Degradation of apolipoprotein B of low density lipoprotein by cultured bovine smooth muscle cells. Accumulation of intermediates in the presence of protease inhibitors.
    Biochimica et biophysica acta, 1981, Feb-23, Volume: 663, Issue:2

    Topics: Ammonium Chloride; Animals; Apolipoproteins; Apolipoproteins B; Cattle; Cells, Cultured; Chloroquine; Electrophoresis, Polyacrylamide Gel; Humans; Leupeptins; Lipoproteins, LDL; Muscle, Smooth, Vascular; Protease Inhibitors

1981
Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells.
    The Biochemical journal, 1994, Oct-01, Volume: 303 ( Pt 1)

    Topics: Amino Acid Sequence; Ammonium Chloride; Animals; Arsenicals; Cell Line, Transformed; Chloroquine; Colchicine; Endocytosis; Epithelium; Hypertonic Solutions; Immune Sera; Immunohistochemistry; Kinetics; Leupeptins; Microscopy, Fluorescence; Molecular Sequence Data; Monensin; Peptides; Rats; Receptors, Neurokinin-1; Recombinant Proteins; Substance P; Time Factors; Transfection

1994
Endocytosis of a cytotoxic human high density lipoprotein results in disruption of acidic intracellular vesicles and subsequent killing of African trypanosomes.
    The Journal of cell biology, 1994, Volume: 126, Issue:1

    Topics: Acids; Ammonium Chloride; Animals; Chloroquine; Dose-Response Relationship, Drug; Endocytosis; Flagella; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Intracellular Membranes; Leupeptins; Lipoproteins, HDL; Microscopy, Immunoelectron; Models, Biological; Monensin; Organelles; Protein Binding; Trypanosoma brucei brucei

1994
Internalization and intracellular processing of an anti-B-cell lymphoma monoclonal antibody, LL2.
    International journal of cancer, 1994, Feb-15, Volume: 56, Issue:4

    Topics: 4-Chloro-7-nitrobenzofurazan; Ammonium Chloride; Antibodies, Monoclonal; Burkitt Lymphoma; Ceramides; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Golgi Apparatus; Humans; Immunoglobulin Fab Fragments; Kinetics; Leupeptins; Lymphoma, B-Cell; Lysosomes; Microscopy, Fluorescence; Tumor Cells, Cultured

1994
Protein degradation in kidney proximal tubule cell monolayers.
    Biochimica et biophysica acta, 1994, Apr-28, Volume: 1221, Issue:3

    Topics: Ammonium Chloride; Animals; Cells, Cultured; Half-Life; Kidney Tubules, Proximal; Leupeptins; Proteins; Rats; Tritium

1994
Normal cellular processing of the beta-amyloid precursor protein results in the secretion of the amyloid beta peptide and related molecules.
    Annals of the New York Academy of Sciences, 1993, Sep-24, Volume: 695

    Topics: Amino Acid Sequence; Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Brefeldin A; Cell Line; Colchicine; Cyclopentanes; Golgi Apparatus; Humans; Kidney; Leupeptins; Lysosomes; Molecular Sequence Data; Monensin; Nocodazole; Protein Processing, Post-Translational; Transfection

1993
beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.
    The Journal of biological chemistry, 1993, Feb-15, Volume: 268, Issue:5

    Topics: Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anti-Bacterial Agents; Base Sequence; Brefeldin A; Cell Line; Cell Membrane; Codon; Colchicine; Cyclopentanes; Golgi Apparatus; Humans; Kidney; Kinetics; Leupeptins; Molecular Sequence Data; Molecular Weight; Monensin; Oligodeoxyribonucleotides; Peptide Fragments; Sequence Deletion; Transfection

1993
Invariant chain retains MHC class II molecules in the endocytic pathway.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Apr-15, Volume: 150, Issue:8 Pt 1

    Topics: Ammonium Chloride; Animals; Antigens, Differentiation, B-Lymphocyte; Cell Line; Chloroquine; Endocytosis; Histocompatibility Antigens Class II; Leupeptins; Lysosomes; Primaquine

1993
Inhibition of apolipoprotein E degradation in a post-Golgi compartment by a cysteine protease inhibitor.
    The Journal of biological chemistry, 1993, Apr-25, Volume: 268, Issue:12

    Topics: Albumins; Ammonium Chloride; Animals; Apolipoproteins E; Brefeldin A; Calcium; Cathepsin B; Cathepsin L; Cathepsins; Chloroquine; CHO Cells; Cricetinae; Cyclopentanes; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Golgi Apparatus; Humans; Kinetics; Leupeptins; Molecular Sequence Data; Transfection; Tumor Cells, Cultured

1993
Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes.
    The Journal of biological chemistry, 1993, Jun-25, Volume: 268, Issue:18

    Topics: 3T3 Cells; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Cycloheximide; Endoplasmic Reticulum; Golgi Apparatus; Hexosaminidases; Leupeptins; Lysosomes; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Peptide Fragments; Receptors, Erythropoietin

1993
Intracellular generation of amyloid beta-protein from amyloid beta-protein precursor fragment by direct cleavage with beta- and gamma-secretase.
    Biochemical and biophysical research communications, 1996, Jan-05, Volume: 218, Issue:1

    Topics: Alzheimer Disease; Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Base Sequence; Cell Line; Chlorocebus aethiops; DNA Primers; Endopeptidases; Humans; Kinetics; Leupeptins; Methylamines; Molecular Sequence Data; Peptide Fragments; Polymerase Chain Reaction; Protease Inhibitors; Protein Processing, Post-Translational; Recombinant Proteins; Transfection

1996
Selective degradation of accumulated secretory proteins in the endoplasmic reticulum. A possible clearance pathway for abnormal tropoelastin.
    The Journal of biological chemistry, 1996, Feb-16, Volume: 271, Issue:7

    Topics: Ammonium Chloride; Animals; Blotting, Northern; Brefeldin A; Cattle; Cells, Cultured; Cycloheximide; Cyclopentanes; Endoplasmic Reticulum; Leucine; Leupeptins; Ligaments; Microscopy, Electron; Nocodazole; Organelles; Protein Synthesis Inhibitors; RNA, Messenger; Serine Proteinase Inhibitors; Transcription, Genetic; Tropoelastin

1996
Absence of lysosomal cleavage in the cytotoxicity mechanism of an immunoconjugate composed of anti-alpha-fetoprotein monoclonal antibody and vindesine analog.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:3

    Topics: alpha-Fetoproteins; Ammonium Chloride; Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Cell Survival; Chromatography, High Pressure Liquid; Culture Media, Conditioned; Endocytosis; Humans; Immunotoxins; Leupeptins; Liver; Lysosomes; Male; Rats; Rats, Wistar; Tumor Cells, Cultured; Vindesine

1996
Differentiation-induced changes in the content, secretion, and subcellular distribution of lysosomal cathepsins in the human colon cancer HT-29 cell line.
    Cell and tissue research, 1997, Volume: 289, Issue:1

    Topics: Ammonium Chloride; Cathepsin B; Cathepsin D; Cathepsin L; Cathepsins; Cell Differentiation; Colon; Colonic Neoplasms; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; HT29 Cells; Humans; Leupeptins; Lysosomes; Mannosephosphates

1997
Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes.
    Cardiovascular research, 1998, Volume: 38, Issue:3

    Topics: Acetylcysteine; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Connexin 43; Cysteine Proteinase Inhibitors; Fluorescent Antibody Technique; Gap Junctions; Hot Temperature; HSP70 Heat-Shock Proteins; Immunoblotting; Leucine; Leupeptins; Lysosomes; Microscopy, Electron; Myocardium; Oligopeptides; Precipitin Tests; Protease Inhibitors; Rats

1998
Calpain inhibitor causes accumulation of ubiquitinated P-glycoprotein at the cell surface: possible role of calpain in P-glycoprotein turnover.
    International journal of oncology, 1999, Volume: 15, Issue:4

    Topics: Acetylcysteine; Ammonium Chloride; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Brefeldin A; Calpain; Cell Membrane; Cysteine Proteinase Inhibitors; Dipeptides; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Humans; K562 Cells; Leucine; Leupeptins; Membrane Proteins; Protein Synthesis Inhibitors; Time Factors; Ubiquitins

1999
Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K(+)-ATPase through proteasomal and endo-/lysosomal proteolytic pathways.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:13

    Topics: Ammonium Chloride; Animals; Biological Transport; Cadmium; Cell Line; Cell Membrane; Chloroquine; Cysteine Endopeptidases; Endosomes; Enzyme Stability; Kidney Tubules, Proximal; Leupeptins; Lysosomes; Models, Biological; Multienzyme Complexes; Oxidative Stress; Proteasome Endopeptidase Complex; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Serine Proteinase Inhibitors; Sodium-Potassium-Exchanging ATPase; Ubiquitins

1999
Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MHC antigens.
    Blood, 2000, Mar-01, Volume: 95, Issue:5

    Topics: Ammonium Chloride; Animals; Antibody Specificity; Antigen Presentation; Antigen-Presenting Cells; Blood Donors; Blood Platelets; Brefeldin A; Chloroquine; Colchicine; Cytosol; Endocytosis; Endosomes; Enzyme Activation; Female; H-2 Antigens; Immunoglobulin G; Interleukin-4; Isoantibodies; Leupeptins; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microtubules; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Transfusion; T-Lymphocytes, Helper-Inducer; Tubulin

2000
Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1.
    The Journal of biological chemistry, 2000, Jul-07, Volume: 275, Issue:27

    Topics: Alzheimer Disease; Ammonium Chloride; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cell Line; Centrifugation, Density Gradient; Cysteine Proteinase Inhibitors; Dogs; Endopeptidases; Humans; Leupeptins; Membrane Proteins; Peptide Fragments; Precipitin Tests; Presenilin-1; Transfection

2000
Biogenesis of lysosomes in marshall cells and in cells of the male reproductive system.
    Molecular reproduction and development, 2001, Volume: 59, Issue:1

    Topics: Ammonium Chloride; Animals; Cathepsin B; Cell Line; Cysteine Proteinase Inhibitors; Endocytosis; Endosomes; Epididymis; Ferritins; Fibroblasts; Glycoproteins; Humans; Immunohistochemistry; Intracellular Membranes; Leupeptins; Lysosomes; Male; Mice; Mice, Transgenic; Sandhoff Disease; Saposins; Tay-Sachs Disease; Testis

2001
Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies.
    The Journal of cell biology, 2002, Mar-04, Volume: 156, Issue:5

    Topics: Acetylcysteine; Ammonium Chloride; Animals; Cell Membrane; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasmic Vesicles; Endocytosis; Endopeptidases; Epidermal Growth Factor; ErbB Receptors; Humans; Immunohistochemistry; Intracellular Membranes; Leupeptins; Microscopy, Confocal; Microscopy, Electron; Multienzyme Complexes; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Transforming Growth Factor alpha; Ubiquitin-Protein Ligases; Ubiquitins

2002
Characterization of the physiological turnover of native and inactivated cytochromes P450 3A in cultured rat hepatocytes: a role for the cytosolic AAA ATPase p97?
    Biochemistry, 2007, Jul-03, Volume: 46, Issue:26

    Topics: Adenine; Adenosine Triphosphatases; Ammonium Chloride; Animals; Autophagy; Boronic Acids; Cell Cycle Proteins; Cross-Linking Reagents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dexamethasone; Dicarbethoxydihydrocollidine; Formaldehyde; Hepatocytes; Leupeptins; Lysosomes; Male; Nuclear Proteins; Polymers; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae Proteins; Troleandomycin; Ubiquitin; Valosin Containing Protein

2007
Lysosome mediated Kir2.1 breakdown directly influences inward rectifier current density.
    Biochemical and biophysical research communications, 2008, Mar-14, Volume: 367, Issue:3

    Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Fluorescent Antibody Technique; Humans; Intracellular Fluid; Leupeptins; Lysosomes; Mice; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Time Factors

2008
Lysosome-dependent degradation of Notch3.
    The international journal of biochemistry & cell biology, 2009, Volume: 41, Issue:12

    Topics: Ammonium Chloride; Animals; Chloroquine; Cysteine Proteinase Inhibitors; Epithelial Cells; HeLa Cells; Humans; Leupeptins; Lysosomes; Mice; Protein Transport; Receptor, Notch3; Receptors, Notch; Signal Transduction; Transfection

2009
Regulation of Notch1 signaling by the APP intracellular domain facilitates degradation of the Notch1 intracellular domain and RBP-Jk.
    Journal of cell science, 2011, Jun-01, Volume: 124, Issue:Pt 11

    Topics: Ammonium Chloride; Amyloid beta-Protein Precursor; Animals; Cell Cycle Proteins; Cell Differentiation; Cell Line; Down-Regulation; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Genes, Reporter; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Leupeptins; Luciferases; Lysosomes; Mice; Mitogen-Activated Protein Kinase 10; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Multimerization; Protein Stability; Protein Structure, Tertiary; Receptor, Notch1; Signal Transduction; Transcriptional Activation; Ubiquitin-Protein Ligases

2011
Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase.
    Journal of cell science, 2012, Mar-01, Volume: 125, Issue:Pt 5

    Topics: Acetylcysteine; Ammonium Chloride; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Gene Knockout Techniques; HEK293 Cells; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Leupeptins; Lysosomes; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Presenilin-1; Presenilin-2; Proteasome Inhibitors; Proteolysis; Receptor, Notch1; Transcription, Genetic; Transcriptional Activation; Ubiquitination

2012
Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase.
    Blood cells, molecules & diseases, 2014, Volume: 53, Issue:4

    Topics: Ammonium Chloride; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Erythropoietin; Gene Expression Regulation; Humans; Janus Kinase 2; Leupeptins; Lymphocytes; Phosphorylation; Proteasome Endopeptidase Complex; Proteolysis; Proto-Oncogene Proteins c-cbl; Proto-Oncogene Proteins pp60(c-src); Pyrazoles; Pyrimidines; RNA, Small Interfering; Signal Transduction; Ubiquitination

2014
The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis.
    Cell death & disease, 2016, Mar-31, Volume: 7

    Topics: Ammonium Chloride; Animals; Autophagy; Beclin-1; Cell Differentiation; Cells, Cultured; Leupeptins; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Knockout; Microscopy, Confocal; Microtubule-Associated Proteins; Mitochondria; Multiprotein Complexes; Muscle Fibers, Skeletal; Myoblasts; RNA Interference; RNA, Small Interfering; Satellite Cells, Skeletal Muscle; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53

2016
Nuclear co-repressor (NCoR) is required to maintain insulin sensitivity in C
    Cell biology international, 2017, Volume: 41, Issue:2

    Topics: Ammonium Chloride; Animals; Blotting, Western; Cell Differentiation; Cell Line; Co-Repressor Proteins; Glucose; Insulin; Insulin Resistance; Leupeptins; Lysosomes; Mice; Models, Biological; Muscle, Skeletal; Phosphorylation; Proteolysis; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering

2017
A Highly Conserved Leucine in Mammarenavirus Matrix Z Protein Is Required for Z Interaction with the Virus L Polymerase and Z Stability in Cells Harboring an Active Viral Ribonucleoprotein.
    Journal of virology, 2018, 06-01, Volume: 92, Issue:11

    Topics: Alanine; Amino Acid Substitution; Ammonium Chloride; Animals; Carrier Proteins; Cell Line; Chlorocebus aethiops; Cricetinae; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Leucine; Leupeptins; Lymphocytic choriomeningitis virus; Lysosomes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Ribonucleoproteins; RNA-Dependent RNA Polymerase; Vero Cells; Viral Proteins; Virus Release

2018
Analysis of Chaperone-Mediated Autophagy.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1880

    Topics: Ammonium Chloride; Animals; Autophagy; Biological Assay; Female; Leupeptins; Liver; Lysosomes; Male; Mice; Mice, Inbred C57BL; Molecular Chaperones; Proteolysis; Rats; Rats, Wistar

2019
Down-regulation effects of IFN-α on p11, 5-htr1b and 5-HTR4 protein levels were affected by NH
    Journal of biosciences, 2019, Volume: 44, Issue:4

    Topics: Ammonium Chloride; Cell Line, Tumor; Cell-Penetrating Peptides; Depression; Gene Expression Regulation; Humans; Interferon-alpha; Leupeptins; Lysosomes; Proteolysis; Receptor, Serotonin, 5-HT1B; Recombinant Proteins; RNA, Messenger; Signal Transduction; Ubiquitin

2019