Compounds > amlodipine

amlodipine and transforming growth factor beta

amlodipine has been researched along with transforming growth factor beta in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (57.89)	29.6817
2010's	7 (36.84)	24.3611
2020's	1 (5.26)	2.80

Authors

Authors	Studies
Kim, D; Kim, HS; Kim, SJ; Ma, KA; Shin, GT	1
Bescós, M; Campistol, JM; Campos, B; Iñigo, P; Lario, S; Oppenheimer, F; Piera, C; Rivera, F	1
Godfraind, T; Krenek, P; Kyselovic, J; Wibo, M	1
Idikio, H; Jugdutt, BI; Kumar, D; Menon, V	1
Chen, J; Gu, Y; Lin, F; Lin, S; Ma, J; Yang, H; Zhu, W	1
Choi, KH; Choi, S; Goo, YS; Ha, SK; Han, DS; Kang, SW; Lee, HY; Park, HC; Xu, ZG	1
Aguirre, R; Andrade, CF; Ara, JM; Arias, M; Bernis, C; Campistol, JM; Galceran, JM; Luño, J; Marín, R; Mora, J; Poveda, R; Praga, M; Prat, MV; Rivera, F	1
Dikmen, T; Gul, S; Kaynar, K; Ovali, E; Ulusoy, S; Vanizor, B	1
Egido, J; García-Puig, J; Gómez-Garre, D; Granados, R; Martín-Ventura, JL; Ruano, M; Sancho, T; Torres, R	1
Rodriguez-Iturbe, B	1
Cao, G; Mastai, R; Mella, J; Muñoz, MC; Pereyra, L; Toblli, JE	1
Jin, D; Miyazaki, M; Sakonjo, H; Takai, S	1
Fujita, H; Harasawa, S; Hirayama, A; Koike, M; Kushiro, T; Nagao, K; Okubo, K; Otsuka, Y	1
Kobara, M; Kojima, Y; Nakano, A; Nakata, T; Noda, K; Oshima, Y; Toba, H; Tojo, C; Wang, J; Yoshida, M	1
Li, J; Li, QX; Song, YJ; Wang, H; Xie, XF	1
Andrei, AM; Banită, IM; Berbecaru-Iovan, A; Munteanu, C; Pisoschi, CG; Popescu, F; Stănciulescu, CE	1
Li, J; Li, QX; Tie, CR; Zheng, F	1
Berg, G; Bertera, FM; Carranza, A; Chiappetta, DA; Del Mauro, JS; Donato, M; Fernandez Machulsky, N; Gelpi, RJ; González, GE; Gorzalczany, SB; Höcht, C; Morales, C; Morettón, MA; Prince, PD; Taira, CA	1
Ganesan, K; Panneerpandian, P; Rao, DB	1

Trials

4 trial(s) available for amlodipine and transforming growth factor beta

Article	Year
Effects of losartan and amlodipine on intrarenal hemodynamics and TGF-beta(1) plasma levels in a crossover trial in renal transplant recipients. Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:4 Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Endothelin-1; Female; Hemodynamics; Humans; Kidney; Kidney Transplantation; Losartan; Male; Middle Aged; Renal Circulation; Renin; Transforming Growth Factor beta; Transforming Growth Factor beta1	2001
Effect of losartan and amlodipine on proteinuria and transforming growth factor-beta1 in patients with IgA nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:6 Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Glomerulonephritis, IGA; Humans; Hypertension; Losartan; Male; Middle Aged; Proteinuria; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Outcome	2003
Antiproteinuric efficacy of losartan in comparison with amlodipine in non-diabetic proteinuric renal diseases: a double-blind, randomized clinical trial. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:9 Topics: Adult; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus; Double-Blind Method; Female; Humans; Kidney Diseases; Losartan; Male; Middle Aged; Prospective Studies; Proteinuria; Transforming Growth Factor beta; Treatment Outcome	2003
Losartan improves resistance artery lesions and prevents CTGF and TGF-beta production in mild hypertensive patients. Kidney international, 2006, Volume: 69, Issue:7 Topics: Adult; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Connective Tissue Growth Factor; Humans; Hypertension; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Losartan; Middle Aged; Reference Values; Transforming Growth Factor beta; Vascular Resistance	2006

Other Studies

15 other study(ies) available for amlodipine and transforming growth factor beta

Article	Year
ACE inhibitors attenuate expression of renal transforming growth factor-beta1 in humans. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 36, Issue:5 Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Female; Gene Expression Regulation; Glomerulonephritis; Glomerulonephritis, IGA; Humans; Kidney; Male; Middle Aged; Nifedipine; Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2000
Effects of amlodipine and lacidipine on cardiac remodelling and renin production in salt-loaded stroke-prone hypertensive rats. British journal of pharmacology, 2001, Volume: 134, Issue:7 Topics: Actins; Amlodipine; Animals; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Collagen Type I; Dihydropyridines; Dose-Response Relationship, Drug; Fibrosis; Gene Expression Regulation; Heart Ventricles; Hypertension; Hypertrophy; Kidney; Male; Muscle, Skeletal; Rats; Rats, Inbred SHR; Renin; RNA, Messenger; Sodium Chloride, Dietary; Transforming Growth Factor beta; Transforming Growth Factor beta1	2001
Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril. Journal of the American College of Cardiology, 2002, May-01, Volume: 39, Issue:9 Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Calcium Channel Blockers; Collagen; Coronary Vessels; Disease Models, Animal; Dogs; Echocardiography; Enalapril; Hydroxyproline; In Vitro Techniques; Myocardial Infarction; Myocardial Reperfusion; Transforming Growth Factor beta; Ventricular Remodeling	2002
Endothelin receptor antagonist combined with a calcium channel blocker attenuates renal injury in spontaneous hypertensive rats with diabetes. Chinese medical journal, 2002, Volume: 115, Issue:7 Topics: Amlodipine; Angiotensin II; Animals; Bosentan; Calcium Channel Blockers; Collagen Type IV; Diabetic Nephropathies; Drug Therapy, Combination; Endothelin Receptor Antagonists; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides; Transforming Growth Factor beta; Transforming Growth Factor beta1	2002
TGF-beta and TNF-alpha producing effects of losartan and amlodipine on human mononuclear cell culture. Nephrology (Carlton, Vic.), 2005, Volume: 10, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Atherosclerosis; Cells, Cultured; Humans; Leukocytes, Mononuclear; Losartan; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2005
Arteriolar remodeling in essential hypertension: are connective tissue growth factor and transforming growth factor involved? Kidney international, 2006, Volume: 69, Issue:7 Topics: Amlodipine; Antihypertensive Agents; Arterioles; Connective Tissue Growth Factor; Humans; Hypertension; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Losartan; Transforming Growth Factor beta	2006
ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats. Obesity (Silver Spring, Md.), 2008, Volume: 16, Issue:4 Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Disease Models, Animal; Fatty Liver; Interleukin-6; Irbesartan; Liver; Liver Cirrhosis; Male; Metabolic Syndrome; Obesity; Perindopril; Rats; Rats, Zucker; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2008
Combination therapy with irbesartan and efonidipine for attenuation of proteinuria in Dahl salt-sensitive rats. Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:9 Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Chemokine CCL2; Collagen Type I; Dihydropyridines; Drug Therapy, Combination; Gene Expression; Glomerulosclerosis, Focal Segmental; Hypertension; Irbesartan; Kidney Glomerulus; Male; NADPH Oxidases; Nitrophenols; Organophosphorus Compounds; Proteinuria; Rats; Rats, Inbred Dahl; Tetrazoles; Transforming Growth Factor beta	2010
Amlodipine suppressed cardiac gene expression of brain natriuretic peptide, transforming growth factor-β₁ and fibronectin mediated by aldosterone in male stroke-prone spontaneously hypertensive rats. The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:12 Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Fibronectins; Gene Expression Regulation; Heart; Hypertension; Male; Myocardium; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Transforming Growth Factor beta	2010
L/N-type calcium channel blocker cilnidipine ameliorates proteinuria and inhibits the renal renin-angiotensin-aldosterone system in deoxycorticosterone acetate-salt hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:4 Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Collagen; Desoxycorticosterone; Dihydropyridines; Disease Models, Animal; Hypertension; Intracellular Signaling Peptides and Proteins; Kidney; Male; Membrane Proteins; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System; Sodium Chloride; Transforming Growth Factor beta; Treatment Outcome	2011
Effects of amlodipine on TGF-β-induced Smad2, 4 expressions in adriamycin toxicity of rat mesangial cells. Archives of toxicology, 2011, Volume: 85, Issue:6 Topics: Amlodipine; Animals; Antibiotics, Antineoplastic; Antihypertensive Agents; Cell Line; Cell Survival; Doxorubicin; Gene Expression Regulation; Humans; Mesangial Cells; Osmolar Concentration; Protective Agents; Rats; Recombinant Proteins; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad4 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1	2011
Role of transforming growth factor β-connective tissue growth factor pathway in dihydropyridine calcium channel blockers-induced gingival overgrowth. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2014, Volume: 55, Issue:2 Topics: Adult; Amlodipine; Calcium Channel Blockers; Calcium Channels, L-Type; Connective Tissue Growth Factor; Female; Gingiva; Gingival Overgrowth; Humans; Immunohistochemistry; Male; Nifedipine; Signal Transduction; Transforming Growth Factor beta	2014
Amlodipine prevents adriamycin-induced toxicity in cultured rat mesangial cells by up-regulation of Smad6, Smad7 expression. Environmental toxicology and pharmacology, 2014, Volume: 38, Issue:1 Topics: Amlodipine; Animals; Antibiotics, Antineoplastic; Antihypertensive Agents; Cell Line; Cell Survival; Doxorubicin; Mesangial Cells; Rats, Sprague-Dawley; Smad6 Protein; Smad7 Protein; Transforming Growth Factor beta; Up-Regulation	2014
Effects of carvedilol or amlodipine on target organ damage in L-NAME hypertensive rats: their relationship with blood pressure variability. Journal of the American Society of Hypertension : JASH, 2017, Volume: 11, Issue:4 Topics: Amlodipine; Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Blood Pressure Determination; Carbazoles; Carvedilol; Collagen; Disease Models, Animal; Fibrosis; Heart Ventricles; Humans; Hypertension; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NG-Nitroarginine Methyl Ester; Propanolamines; Rats; Rats, Wistar; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2017
Calcium channel blockers lercanidipine and amlodipine inhibit YY1/ERK/TGF-β mediated transcription and sensitize the gastric cancer cells to doxorubicin. Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 74 Topics: Amlodipine; Antibiotics, Antineoplastic; Calcium Channel Blockers; Cell Line; Cell Survival; Dihydropyridines; Doxorubicin; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Stomach Neoplasms; Transcription, Genetic; Transcriptome; Transforming Growth Factor beta; YY1 Transcription Factor	2021