Compounds > amlodipine

amlodipine and tacrolimus

amlodipine has been researched along with tacrolimus in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (26.67)29.6817
2010's11 (73.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dong, G; Liu, N; Sheng, C; Tu, J; Wang, Y1
Aoyama, T; Esaki, M; Fujiwara, H; Fujiwara, T; Kanamori, H; Kawasaki, M; Maruyama, R; Minatoguchi, S; Miyata, S; Nakagawa, M; Ogino, A; Okada, H; Takemura, G; Ushikoshi, H1
Agarwal, SK; Bhowmik, D; Gupta, A; Khaira, A; Mahajan, S; Rathi, OP; Tiwari, SC1
Baudouin, V; Deschênes, G; Fakhoury, M; Jacqz-Aigrain, E; Storme, T; Zhao, W1
Cheng, ZN; Li, J; Li, PJ; Liu, Z; Tan, HY; Wang, CJ; Yang, GP; Yang, M; Yuan, H; Zhang, BK; Zhou, LY; Zhou, YN; Zuo, XC1
Barrett, JS; Cheng, ZN; Guo, R; Li, J; Li, PJ; Li, ZJ; Liu, SK; Liu, Z; Ouyang, DS; Tan, HY; Wang, CJ; Wang, JL; Xie, YL; Yang, GP; Yuan, H; Zhang, BK; Zhou, LY; Zhou, YN; Zuo, XC1
McBennett, K; Sahay, S; Sheers, T1
Hesselink, DA; Hoorn, EJ; Moes, AD; van den Meiracker, AH; Zietse, R1
Aronowitz, P; Kendall, P; Pugashetti, JV1

Reviews

2 review(s) available for amlodipine and tacrolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Emerging New Targets for the Treatment of Resistant Fungal Infections.
    Journal of medicinal chemistry, 2018, 07-12, Volume: 61, Issue:13

    Topics: Antifungal Agents; Drug Resistance, Fungal; Humans; Molecular Targeted Therapy; Mycoses

2018

Trials

2 trial(s) available for amlodipine and tacrolimus

ArticleYear
Effect of CYP3A5*3 polymorphism on pharmacokinetic drug interaction between tacrolimus and amlodipine.
    Drug metabolism and pharmacokinetics, 2013, Volume: 28, Issue:5

    Topics: Amlodipine; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Immunosuppressive Agents; Male; Polymorphism, Single Nucleotide; Tacrolimus; Young Adult

2013
Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 69, Issue:6

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Cross-Over Studies; Edema; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Proteinuria; Tacrolimus; Treatment Outcome

2017

Other Studies

11 other study(ies) available for amlodipine and tacrolimus

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Amlodipine inhibits granulation tissue cell apoptosis through reducing calcineurin activity to attenuate postinfarction cardiac remodeling.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Amlodipine; Animals; Apoptosis; bcl-Associated Death Protein; Calcineurin; Calcineurin Inhibitors; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Coronary Vessels; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; fas Receptor; Granulation Tissue; Hydralazine; Ligation; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Phosphorylation; Research Design; Tacrolimus; Time Factors; Vasodilator Agents; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2007
Galactorrhoea and mastalgia in a renal transplant recipient on tacrolimus and amlodipine.
    Nephrology (Carlton, Vic.), 2009, Volume: 14, Issue:7

    Topics: Adult; Amlodipine; Breast; Drug Interactions; Female; Galactorrhea; Humans; Kidney Transplantation; Tacrolimus

2009
Pharmacokinetic interaction between tacrolimus and amlodipine in a renal transplant child.
    Transplantation, 2012, Apr-15, Volume: 93, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child, Preschool; Cytochrome P-450 CYP3A; Drug Interactions; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Pharmacogenetics; Tacrolimus; Treatment Outcome

2012
Effect of amlodipine on the pharmacokinetics of tacrolimus in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2013, Volume: 43, Issue:8

    Topics: Administration, Oral; Amlodipine; Animals; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tacrolimus

2013
Calcineurin-inhibitor induced pain syndrome in a lung transplant patient.
    Transplant international : official journal of the European Society for Organ Transplantation, 2013, Volume: 26, Issue:8

    Topics: Adult; Amlodipine; Arthralgia; Calcineurin Inhibitors; Cystic Fibrosis; Humans; Immunosuppressive Agents; Lung Transplantation; Tacrolimus

2013
Drug-induced gingival overgrowth after renal transplantation.
    Journal of general internal medicine, 2017, Volume: 32, Issue:12

    Topics: Amlodipine; Calcium Channel Blockers; Drug Interactions; Gingival Overgrowth; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Tacrolimus; Young Adult

2017