amlodipine and spironolactone

amlodipine has been researched along with spironolactone in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (44.00)	29.6817
2010's	13 (52.00)	24.3611
2020's	1 (4.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Duprez, D; Krause, S; Kuse-Hamilton, J; Roniker, B; St Hillaire, R; Weber, MA; White, WB	1
Akhras, KS; Anderson, R; Bittman, RM; Hollenberg, NK; Krause, SL; Williams, GH	1
Burns, D; Kleiman, J; Krause, S; Phillips, RA; Pitt, B; Reichek, N; Roniker, B; Willenbrock, R; Williams, GH; Zannad, F	1
Burgess, E	1
Laustsen, G; Wimmett, L	1
Czupryniak, L; Loba, J; Pawłowski, M; Saryusz-Wolska, M	1
Appleton, DS; Brown, MJ; Mir, FA	1
Ahokas, RA; Baburyan, NY; Bhattacharya, SK; Deshmukh, PA; Gandhi, MS; Gerling, IC; Johnson, PL; Kamalov, G; Sun, Y; Weber, KT	1
Du, J; Fan, YY; Hitomi, H; Kimura, S; Kiyomoto, H; Kohno, M; Kong, CZ; Nakano, D; Nishiyama, A; Noma, T	1
Chen, C; Ding, G; Hu, F; Liang, W; Ren, Z; Shi, J; Singhal, PC; van Goor, H	1
Inagaki, K; Kumagai, I; Makino, H; Miyoshi, T; Nakamura, E; Ogura, T; Otsuka, F; Suzuki, J; Tanabe, K; Tsukamoto, N	1
Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Nakamura, T; Nako, H; Ogawa, H; Tokutomi, Y; Yamamoto, E; Yasuda, O	1
Funder, JW	1
Purnamasari, D; Soebijanto, N	1
Handler, J	1
Azizi, M; Bobrie, G; Chatellier, G; Frank, M; Ménard, J; Perdrix, L; Plouin, PF	1
O'Brien, E	1
van der Merwe, V; van der Merwe, W	1
Argyropoulou, MI; Christopoulou, F; Elisaf, M; Kosta, P; Rizos, EC	1
Alves, PH; Castro, CH; Colugnati, DB; Macedo, LM; Mendes, EP; Nunes, AD; Pedrino, GR; Santos, RA; Souza, AP	1
Kassie, GM; Kerr, M; Moffat, A; Pratt, N; Roughead, EE	1

Reviews

3 review(s) available for amlodipine and spironolactone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Eplerenone in hypertension. Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:12 Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Enalapril; Eplerenone; Humans; Hypertension; Spironolactone	2004
2004 drug approval highlights: FDA update. The Nurse practitioner, 2005, Volume: 30, Issue:2 Topics: Administration, Cutaneous; Amlodipine; Anti-Bacterial Agents; Antidepressive Agents; Bronchodilator Agents; Cardiovascular Agents; Drug Approval; Drug Combinations; Duloxetine Hydrochloride; Eplerenone; Estradiol; Excitatory Amino Acid Antagonists; Female; Gastrointestinal Agents; Heptanoic Acids; Humans; Ketolides; Male; Memantine; Osteoporosis, Postmenopausal; Pyrroles; Rifamycins; Rifaximin; Scopolamine Derivatives; Spironolactone; Thiophenes; Tiotropium Bromide; United States	2005

Trials

5 trial(s) available for amlodipine and spironolactone

Article	Year
Effects of the selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5 Topics: Aged; Albuminuria; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Creatinine; Diarrhea; Double-Blind Method; Eplerenone; Female; Headache; Heart Rate; Humans; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Nausea; Pulsatile Flow; Spironolactone; Systole; Treatment Outcome	2003
Symptoms and the distress they cause: comparison of an aldosterone antagonist and a calcium channel blocking agent in patients with systolic hypertension. Archives of internal medicine, 2003, Jul-14, Volume: 163, Issue:13 Topics: Aged; Amlodipine; Analysis of Variance; Calcium Channel Blockers; Eplerenone; Female; Humans; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Quality of Life; Renin-Angiotensin System; Spironolactone; Statistics, Nonparametric; Treatment Outcome	2003
Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study. Circulation, 2003, Oct-14, Volume: 108, Issue:15 Topics: Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Enalapril; Eplerenone; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Myocardium; Potassium; Renin-Angiotensin System; Spironolactone; Treatment Outcome	2003
Circadian blood pressure variation and antihypertensive medication adjustment in normoalbuminuric type 2 diabetes patients. Kidney & blood pressure research, 2007, Volume: 30, Issue:3 Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypertension, Renal; Indapamide; Indoles; Male; Middle Aged; Nitrendipine; Perindopril; Spironolactone	2007
Greater efficacy of aldosterone blockade and diuretic reinforcement vs. dual renin-angiotensin blockade for left ventricular mass regression in patients with resistant hypertension. Journal of hypertension, 2014, Volume: 32, Issue:10 Topics: Adolescent; Adult; Aged; Aldosterone; Amiloride; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Bisoprolol; Blood Pressure; Blood Pressure Determination; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Hypertrophy, Left Ventricular; Irbesartan; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Ramipril; Renin; Renin-Angiotensin System; Spironolactone; Tetrazoles; Young Adult	2014

Other Studies

17 other study(ies) available for amlodipine and spironolactone

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Lessons in the diagnosis and management of Conn's syndrome. Clinical medicine (London, England), 2007, Volume: 7, Issue:5 Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Amiloride; Amlodipine; Calcium Channel Blockers; Humans; Hydrocortisone; Male; Middle Aged; Spironolactone	2007
Coupled calcium and zinc dyshomeostasis and oxidative stress in cardiac myocytes and mitochondria of rats with chronic aldosteronism. Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:5 Topics: Aldehydes; Aldosterone; Amlodipine; Animals; Calcium; Calcium Channel Blockers; Chronic Disease; Disease Models, Animal; Glutathione Peroxidase; Homeostasis; Hydrogen Peroxide; Hyperaldosteronism; Male; Metallothionein; Mineralocorticoid Receptor Antagonists; Mitochondria, Heart; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spironolactone; Superoxide Dismutase; Tyrosine; Zinc	2009
Mineralocorticoid receptor blockade and calcium channel blockade have different renoprotective effects on glomerular and interstitial injury in rats. American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:3 Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cell Hypoxia; Creatinine; Drug Therapy, Combination; Endothelial Cells; Eplerenone; Fibrosis; Hypertension; Immediate-Early Proteins; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Mineralocorticoid Receptor Antagonists; Podocytes; Protein Serine-Threonine Kinases; Proteinuria; Rats; Rats, Inbred Dahl; Receptors, Mineralocorticoid; Sodium Chloride, Dietary; Spironolactone; Time Factors; Vascular Endothelial Growth Factor A	2009
Disparate effects of eplerenone, amlodipine and telmisartan on podocyte injury in aldosterone-infused rats. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:3 Topics: Albuminuria; Aldosterone; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Benzimidazoles; Benzoates; Blotting, Western; Calcium Channel Blockers; Eplerenone; Immunoenzyme Techniques; Kidney Glomerulus; Male; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Podocytes; Proteinuria; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Telmisartan	2011
Effects of eplerenone on nephrotic syndrome in a patient with renovascular hypertension. Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:3 Topics: Amlodipine; Antihypertensive Agents; Dihydropyridines; Eplerenone; Humans; Hypertension, Renovascular; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Nephrotic Syndrome; Proteinuria; Radiography; Spironolactone; Treatment Outcome	2011
Eplerenone potentiates protective effects of amlodipine against cardiovascular injury in salt-sensitive hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:7 Topics: Aldosterone; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Drug Therapy, Combination; Endothelium, Vascular; Eplerenone; Heart; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary; Spironolactone; Superoxides; Treatment Outcome	2011
Eplerenone, amlodipine and experimental hypertension: one plus one equals three. Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:7 Topics: Amlodipine; Animals; Antihypertensive Agents; Eplerenone; Heart; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Spironolactone	2011
The difficulty of medical management of Cushing disease. Acta medica Indonesiana, 2011, Volume: 43, Issue:2 Topics: Amlodipine; Antihypertensive Agents; Captopril; Clonidine; Female; Humans; Mineralocorticoid Receptor Antagonists; Pituitary ACTH Hypersecretion; Potassium; Spironolactone; Young Adult	2011
Commentary in support of a highly effective hypertension treatment algorithm. Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:12 Topics: Adult; Algorithms; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Spironolactone; Treatment Outcome; United States	2013
If I had resistant hypertension. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pyrroles; Spironolactone; Tetrazoles; Treatment Failure; Treatment Outcome	2014
Difficult Hypertension Clinic Utilizing a Nurse Specialist: A Cost-Efficient Model for the Modern Era? Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cost-Benefit Analysis; Female; Humans; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; New Zealand; Nurse Practitioners; Spironolactone; Young Adult	2015
Does this patient have hypertensive encephalopathy? Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Brain; Carbazoles; Carvedilol; Computed Tomography Angiography; Confusion; Creatinine; Electrocardiography; Glomerular Filtration Rate; Hallucinations; Headache; Heart; Humans; Hydrochlorothiazide; Hypertension; Hypertensive Encephalopathy; Irbesartan; Magnetic Resonance Imaging; Male; Middle Aged; Propanolamines; Renal Artery Obstruction; Spironolactone; Tetrazoles; Ultrasonography	2016
Influence of antihypertensive drugs on aortic and coronary effects of Ang-(1-7) in pressure-overloaded rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, Mar-23, Volume: 50, Issue:4 Topics: Amlodipine; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Calcium Channel Blockers; Captopril; Coronary Vessels; Losartan; Male; Mineralocorticoid Receptor Antagonists; Models, Animal; Peptide Fragments; Rats, Wistar; Reproducibility of Results; Spironolactone; Time Factors; Vasoconstriction; Vasodilation	2017
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care. Drug safety, 2022, Volume: 45, Issue:11 Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; Case-Control Studies; Ciprofloxacin; Diclofenac; Furosemide; Humans; Ibuprofen; Metformin; Naproxen; Omeprazole; Primary Health Care; Ramipril; Simvastatin; Spironolactone; Sulfamethoxazole; Telmisartan; Trimethoprim; Valacyclovir; Zoledronic Acid	2022