amlodipine has been researched along with propranolol in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.78) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 8 (22.22) | 29.6817 |
| 2010's | 20 (55.56) | 24.3611 |
| 2020's | 2 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Herbette, LG; Mason, RP; Rhodes, DG | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dalipram, RA; Dusting, GJ; Sobey, CG; Woodman, OL | 1 |
| Burges, RA; Carter, AJ; Dodd, MG; Gardiner, DG; Sutton, MR | 1 |
| Dalipram, RA; Sobey, CG; Woodman, OL | 1 |
| Block, LH; Nauck, M; Rödler, S; Roth, M; Tamm, M | 1 |
| Orekhov, AN; Pivovarova, EM; Tertov, VV | 1 |
| Bertoluci, MC; Oliveira, FR; Schmid, H; Schmidt, A; Thomazelli, FC; Uebel, D | 1 |
| Chiba, S; Fujisawa, M; Koike, H; Yorikane, R | 1 |
| Accardo, S; Americo, L; Castello, A; Cicero, S; Sarullo, FM; Schicchi, R; Schirò, M | 1 |
| Del Giaccio, A; Eblen-Zajjur, A | 1 |
| Rousu, T; Tolonen, A | 1 |
| Davis, J; Gardner, I; Jones, HM; Rowland, M; Small, H | 1 |
| Bahrololoom, M; Bozorgmehr, MR; Chamani, J; Housaindokht, MR; Rouhbakhsh Zaeri, Z | 1 |
| Beil, M; Danhof, M; Fu, F; Luttringer, O; Ploeger, BA; Rigel, DF; Snelder, N; Stanski, DR | 1 |
| Rothwell, PM; Webb, AJ | 1 |
| Cui, WY; Long, CL; Wang, H; Wang, RH; Zhang, YF; Zhong, ML; Zhou, HM | 1 |
| Du, Y; Feng, Z; Huang, Z; Sun, X; Zhao, S | 1 |
| Banks, CE; Khairy, M; Khorshed, AA | 1 |
| Chen, C; Ding, W; Du, Y; Ma, X; Sun, X; Tao, Y | 1 |
| Du, Y; Kan, Z; Ma, M; Zhang, J; Zhang, X | 1 |
| Du, Y; Feng, Z; Gan, J; Li, X; Ma, M; Miao, P; Zhang, J; Zhang, L | 1 |
2 review(s) available for amlodipine and propranolol
| Article | Year |
|---|---|
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes.
Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship | 1991 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for amlodipine and propranolol
| Article | Year |
|---|---|
Urinary TGF-beta1 reduction related to a decrease of systolic blood pressure in patients with type 2 diabetes and clinical diabetic nephropathy.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Captopril; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propranolol; Ramipril; Transforming Growth Factor beta1 | 2006 |
Cardiovascular drugs in human mechanical nociception: digoxin, amlodipine, propranolol, pindolol and atenolol.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Cardiovascular Diseases; Cross-Sectional Studies; Digoxin; Female; Humans; Male; Middle Aged; Nociceptors; Pindolol; Propranolol; Young Adult | 2010 |
Magnetic Resonance Imaging Measurement of Transmission of Arterial Pulsation to the Brain on Propranolol Versus Amlodipine.
Topics: Adolescent; Adult; Amlodipine; Antihypertensive Agents; Aorta; Blood Pressure Determination; Cerebrovascular Circulation; Cross-Over Studies; Female; Healthy Volunteers; Humans; Magnetic Resonance Imaging; Male; Middle Cerebral Artery; Pilot Projects; Propranolol; Pulsatile Flow; Young Adult | 2016 |
31 other study(ies) available for amlodipine and propranolol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinol.
Topics: Acetylcholine; Allopurinol; Amlodipine; Animals; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Nifedipine; Nitroglycerin; Propranolol | 1992 |
The hemodynamic properties of amlodipine in anesthetised and conscious dogs: comparison with nitrendipine and influence of beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Amlodipine; Anesthesia; Animals; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Male; Nifedipine; Nitrendipine; Propranolol; Time Factors; Vascular Resistance | 1989 |
Allopurinol and amlodipine improve coronary vasodilatation after myocardial ischaemia and reperfusion in anaesthetized dogs.
Topics: Allopurinol; Amlodipine; Anesthetics; Animals; Dogs; Endothelium, Vascular; Female; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Propranolol; Vasodilator Agents | 1993 |
Ca(2+)-channel blockers modulate the expression of interleukin-6 and interleukin-8 genes in human vascular smooth muscle cells.
Topics: Adrenergic beta-Antagonists; Amlodipine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Diuretics; Felodipine; Fibroblasts; Furosemide; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Isradipine; Lung; Muscle Proteins; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Propranolol; Transcription, Genetic | 1995 |
The effects of antihypertensive agents on atherosclerosis-related parameters of human aorta intimal cells.
Topics: Adult; Amlodipine; Antihypertensive Agents; Aorta; Arteriosclerosis; Cell Division; Cells, Cultured; Cholesterol; DNA; Humans; Indoles; Male; Middle Aged; Muscle, Smooth, Vascular; Propranolol; Protein Biosynthesis; Tunica Intima; Verapamil | 1998 |
Chronotropic effects of azelnidipine, a slow- and long-acting dihydropyridine-type calcium channel blocker, in anesthetized dogs: a comparison with amlodipine.
Topics: Adjuvants, Anesthesia; Amlodipine; Anesthesia; Animals; Atropine; Azetidinecarboxylic Acid; Baroreflex; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Coronary Vessels; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Heart Rate; Infusions, Intravenous; Injections, Intravenous; Pentobarbital; Perfusion; Propranolol; Sympathetic Nervous System; Time Factors | 2009 |
Tako-tsubo cardiomyopathy observed in a patient with sepsis and transient hyperthyroidism.
Topics: Amlodipine; Anti-Bacterial Agents; Antihypertensive Agents; Antithyroid Agents; Aspirin; Echocardiography; Electrocardiography; Female; Glucocorticoids; Humans; Hyperthyroidism; Methimazole; Middle Aged; Ofloxacin; Platelet Aggregation Inhibitors; Prednisone; Propranolol; Ramipril; Sepsis; Takotsubo Cardiomyopathy | 2009 |
Characterization of cyanide-trapped methylated metabonates formed during reactive drug metabolite screening in vitro.
Topics: Amlodipine; Ciprofloxacin; Drug Evaluation, Preclinical; Female; Humans; Isotope Labeling; Male; Metabolomics; Microsomes, Liver; Pharmaceutical Preparations; Potassium Cyanide; Propranolol | 2011 |
Measurement of binding of basic drugs to acidic phospholipids using surface plasmon resonance and incorporation of the data into mechanistic tissue composition equations to predict steady-state volume of distribution.
Topics: Amlodipine; Hydrogen-Ion Concentration; Liposomes; Models, Chemical; Pharmaceutical Preparations; Pharmacokinetics; Phosphatidylserines; Propranolol; Protein Binding; Sulfonamides; Surface Plasmon Resonance; Tissue Distribution | 2011 |
Investigation of the behavior of HSA upon binding to amlodipine and propranolol: Spectroscopic and molecular modeling approaches.
Topics: Amlodipine; Circular Dichroism; Humans; Models, Molecular; Propranolol; Protein Binding; Protein Structure, Secondary; Serum Albumin; Spectrophotometry, Ultraviolet; Vasodilator Agents | 2012 |
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Amlodipine; Animals; Atropine; Enalapril; Hemodynamics; Hydrochlorothiazide; Hypertension; Male; Models, Biological; Prazosin; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY | 2014 |
Synergisms of cardiovascular effects between iptakalim and amlodipine, hydrochlorothiazide or propranolol in anesthetized rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Drug Synergism; Heart Rate; Hydrochlorothiazide; Hypertension; Propranolol; Propylamines; Rats | 2015 |
Enantioseparation of propranolol, amlodipine and metoprolol by electrochromatography using an open tubular capillary modified with β-cyclodextrin and poly(glycidyl methacrylate) nanoparticles.
Topics: Amlodipine; beta-Cyclodextrins; Capillary Electrochromatography; Metoprolol; Nanoparticles; Polymethacrylic Acids; Propranolol; Stereoisomerism | 2019 |
Electrochemical determination of antihypertensive drugs by employing costless and portable unmodified screen-printed electrodes.
Topics: Amiloride; Amlodipine; Antihypertensive Agents; Drug Evaluation, Preclinical; Electrochemical Techniques; Electrodes; Humans; Printing; Propranolol; Timolol; Triamterene | 2019 |
Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs.
Topics: Amlodipine; beta-Cyclodextrins; Capillary Electrochromatography; Metal-Organic Frameworks; Metoprolol; Propanolamines; Propranolol; Sotalol; Stereoisomerism | 2019 |
Zeolitic imidazolate framework-67-modified open-tubular column with cyclodextrin for enantioseparation in capillary electrochromatography.
Topics: Amlodipine; Atenolol; Capillary Electrochromatography; Cyclodextrins; Histidine; Metoprolol; Propranolol; Stereoisomerism; Zeolites | 2022 |
Carboxymethyl-β-cyclodextrin and histidine-zeolitic imidazolate framework-8 used for enantioseparation of three basic drugs in open-tubular capillary electrochromatography.
Topics: Amlodipine; Atenolol; beta-Cyclodextrins; Capillary Electrochromatography; Histidine; Propranolol; Stereoisomerism; Zeolites | 2022 |