Compounds > amlodipine

amlodipine and prazosin

amlodipine has been researched along with prazosin in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (20.00)	18.2507
2000's	9 (45.00)	29.6817
2010's	7 (35.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chang, RS; Chen, TB; Chiu, G; Fang, J; Forray, C; Gluchowski, C; Hong, X; Marzabadi, MR; Miao, SW; Nagarathnam, D; O'Malley, SS; Wetzel, JM; Wong, WC	1
Topliss, JG; Yoshida, F	1
Caron, G; Ermondi, G; Lorenti, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ajayi, AA; Raji, MA	1
Fujita, M; Kihara, Y; Nakae, I; Nohara, R; Sasayama, S; Tamaki, S; Tanaka, T	1
Chen, G; Liu, H; Liu, P; Liu, Z; Mao, G; Na, Y; Qin, X; Wang, B; Wang, X; Xu, X	1
Chen, GL; Liu, HP; Liu, P; Xu, XP	1
Fang, J; Li, YL; Liu, HP; Qin, XH; Xu, XP; Yang, C; Zhang, X	1
Albarran, HA; Rodriguez, GC; Zeron, HM	1
Beil, M; Danhof, M; Fu, F; Luttringer, O; Ploeger, BA; Rigel, DF; Snelder, N; Stanski, DR	1

Reviews

2 review(s) available for amlodipine and prazosin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
New drugs for hypertension--variations on old themes. Drug and therapeutics bulletin, 1991, Mar-18, Volume: 29, Issue:6 Topics: Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dihydropyridines; Doxazosin; Humans; Hypertension; Isradipine; Nifedipine; Prazosin; Verapamil	1991

Trials

3 trial(s) available for amlodipine and prazosin

Article	Year
Acute cardiovascular effects of the concurrent administration of enalapril, prazosin or amlodipine in healthy Nigerians. International journal of cardiology, 1994, Mar-15, Volume: 44, Issue:1 Topics: Adult; Amlodipine; Black People; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Echocardiography; Enalapril; Heart Rate; Hemodynamics; Humans; Male; Nigeria; Prazosin; Reflex	1994
Efficacy of combined amlodipine/terazosin therapy in male hypertensive patients with lower urinary tract symptoms: a randomized, double-blind clinical trial. Urology, 2009, Volume: 74, Issue:1 Topics: Adrenergic alpha-Antagonists; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Male; Middle Aged; Prazosin; Prostatism	2009
[Amlodipine combined with terazosin reduces postvoid residual and the risk of acute urinary retention]. Zhonghua nan ke xue = National journal of andrology, 2009, Volume: 15, Issue:5 Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Male; Middle Aged; Prazosin; Prospective Studies; Prostatic Hyperplasia; Treatment Outcome; Urinary Retention; Urodynamics	2009

Other Studies

15 other study(ies) available for amlodipine and prazosin

Article	Year
Design and synthesis of novel dihydropyridine alpha-1a antagonists. Bioorganic & medicinal chemistry letters, 1999, Oct-04, Volume: 9, Issue:19 Topics: Adrenergic Antagonists; Animals; Calcium Channels; Dihydropyridines; Dogs; Humans; Male; Molecular Structure; Phenylephrine; Prostate; Prostatic Hyperplasia; Protein Binding; Rats; Stereoisomerism	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction. Journal of medicinal chemistry, 2004, Jul-29, Volume: 47, Issue:16 Topics: Chromatography, Affinity; Hydrogen-Ion Concentration; Ions; Models, Molecular; Molecular Conformation; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin, Bovine; Ultracentrifugation	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Importance of alpha 1-sympathetic activity for diurnal change in ischemic threshold in patients with stable angina. Clinical cardiology, 1998, Volume: 21, Issue:5 Topics: Adrenergic alpha-Antagonists; Adult; Aged; Amlodipine; Analysis of Variance; Angina Pectoris; Calcium Channel Blockers; Circadian Rhythm; Differential Threshold; Female; Humans; Male; Middle Aged; Myocardial Infarction; Prazosin; Vascular Resistance	1998
Amlodipine alone or combined with terazosin improves lower urinary tract disorder in rat models of benign prostatic hyperplasia or detrusor instability: focus on detrusor overactivity. BJU international, 2009, Volume: 104, Issue:11 Topics: Adrenergic alpha-Antagonists; Amlodipine; Animals; Calcium Channel Blockers; Drug Therapy, Combination; Female; Male; Prazosin; Prostatic Hyperplasia; Prostatism; Rats; Rats, Sprague-Dawley; Treatment Outcome; Urinary Bladder, Overactive	2009
Hemodynamic evaluation and anti-hypertensive schemes used in puerperal women following pre-eclampsia. Mymensingh medical journal : MMJ, 2012, Volume: 21, Issue:2 Topics: Adolescent; Adult; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Catheterization, Swan-Ganz; Drug Therapy, Combination; Eclampsia; Electric Impedance; Female; Furosemide; Hemodynamics; Humans; Nitroprusside; Postpartum Period; Prazosin; Pre-Eclampsia; Pregnancy; Telmisartan; Young Adult	2012
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling. British journal of pharmacology, 2014, Volume: 171, Issue:22 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Amlodipine; Animals; Atropine; Enalapril; Hemodynamics; Hydrochlorothiazide; Hypertension; Male; Models, Biological; Prazosin; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY	2014