amlodipine and nisoldipine

amlodipine has been researched along with nisoldipine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's7 (25.93)18.2507
2000's11 (40.74)29.6817
2010's8 (29.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herbette, LG; Mason, RP; Rhodes, DG1
Topliss, JG; Yoshida, F1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Sun, H1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Burburan, PJ; Matubia, VN; Parkin, DW; Ramcharan, SS; Rosario, I; Shea, TA; Stockman, BJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arena, JP; Chin, S; Kass, RS1
Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP1
Gilar, M; Tesarová, E; Uhrová, M1
Curry, P; Dens, J; Hagel, H; Melcher, A1
Furberg, CD; Pahor, M; Psaty, BM1
Pahor, M; Tatti, P1
Ellsworth, A; Fink, KS1
Mak, IT; Weglicki, WB; Zhang, J1
Ciuryla, V; Enzmann, G; Johnson, R; Pershadsingh, HA; Reisin, E; Whitcomb, C1
Hilleman, DE; Lenz, TL; Wurdeman, RL1
Bittar, N; Cooper-DeHoff, RM; Hutchinson, HG; Koren, M; Michelson, EL; Minkwitz, MC; Pepine, CJ; Thadani, U; Weiss, RJ1
Dens, J; Desmet, W; Piessens, J1
Ferdinand, K; Noveck, RJ; Saunders, E; White, WB1

Reviews

4 review(s) available for amlodipine and nisoldipine

ArticleYear
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship

1991
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Nisoldipine CC: clinical experience in ischaemic heart disease.
    Cardiology, 1997, Volume: 88 Suppl 1

    Topics: Amlodipine; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Myocardial Ischemia; Nisoldipine; Randomized Controlled Trials as Topic

1997
An updated meta-analysis of calcium-channel blockers in the prevention of restenosis after coronary angioplasty.
    American heart journal, 2003, Volume: 145, Issue:3

    Topics: Amlodipine; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Confidence Intervals; Coronary Disease; Coronary Restenosis; Humans; Incidence; Nisoldipine; Odds Ratio; Randomized Controlled Trials as Topic

2003

Trials

6 trial(s) available for amlodipine and nisoldipine

ArticleYear
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:4

    Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nisoldipine; Prospective Studies; Random Allocation; Verapamil

1987
The Fosinopril versus Amlodipine Cardiovascular Events Trial (FACET) and combination therapies.
    The American journal of cardiology, 1999, Mar-01, Volume: 83, Issue:5

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Drug Combinations; Enalapril; Follow-Up Studies; Fosinopril; Heart Diseases; Humans; Hypertension; Nisoldipine; Prospective Studies; Reproducibility of Results; Risk Factors; Treatment Outcome

1999
A comparison of nisoldipine ER and amlodipine for the treatment of mild to moderate hypertension.
    International journal of clinical practice, 2000, Volume: 54, Issue:8

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Determination; Delayed-Action Preparations; Double-Blind Method; Drug Costs; Female; Humans; Hypertension; Least-Squares Analysis; Male; Middle Aged; Nisoldipine; Single-Blind Method; Therapeutic Equivalency; Treatment Outcome

2000
Comparison of 24-hour blood pressure profiles in patients with hypertension who were switched from amlodipine to nisoldipine.
    Pharmacotherapy, 2001, Volume: 21, Issue:8

    Topics: Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over Studies; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nisoldipine; Patient Compliance; Time Factors

2001
Comparison of effects of nisoldipine-extended release and amlodipine in patients with systemic hypertension and chronic stable angina pectoris.
    The American journal of cardiology, 2003, Feb-01, Volume: 91, Issue:3

    Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nisoldipine

2003
Comparative efficacy and safety of nisoldipine extended-release (ER) and amlodipine (CESNA-III study) in African American patients with hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:9 Pt 1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Incidence; Male; Middle Aged; Nisoldipine; Prospective Studies; Systole; Treatment Outcome; United States; Vasodilator Agents

2003

Other Studies

17 other study(ies) available for amlodipine and nisoldipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase.
    Bioorganic & medicinal chemistry letters, 2014, Feb-15, Volume: 24, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Dose-Response Relationship, Drug; Molecular Structure; N-Glycosyl Hydrolases; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Rabeprazole; Structure-Activity Relationship; Trichomonas vaginalis

2014
Block of L-type calcium channels by charged dihydropyridines. Sensitivity to side of application and calcium.
    The Journal of general physiology, 1991, Volume: 98, Issue:1

    Topics: Amlodipine; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Diffusion; Dihydropyridines; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Myocardium; Nifedipine; Nisoldipine; Receptors, Nicotinic

1991
Enantiomer separation of dihydropyridine calcium antagonists with cyclodextrins as chiral selectors: structural correlation.
    Journal of chromatography. B, Biomedical applications, 1996, May-31, Volume: 681, Issue:1

    Topics: Amlodipine; Buffers; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cyclodextrins; Dihydropyridines; Electrolytes; Electrophoresis, Capillary; Isradipine; Microspheres; Molecular Conformation; Nimodipine; Nisoldipine; Nitrendipine; Sodium Dodecyl Sulfate; Solvents; Stereoisomerism; Surface-Active Agents

1996
Treatment of hypertensive patients with diabetes.
    Lancet (London, England), 1998, Mar-07, Volume: 351, Issue:9104

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Case-Control Studies; Cohort Studies; Diabetes Complications; Enalapril; Fosinopril; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Nisoldipine; Randomized Controlled Trials as Topic

1998
Antihypertensive treatment and CHD in the elderly.
    American family physician, 1999, Sep-15, Volume: 60, Issue:4

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Complications; Double-Blind Method; Felodipine; Fosinopril; Humans; Hypertension; Myocardial Infarction; Nisoldipine; Nitrendipine; Randomized Controlled Trials as Topic

1999
Cytoprotective properties of nisoldipine and amlodipine against oxidative endothelial cell injury.
    Annals of the New York Academy of Sciences, 2000, Volume: 899

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cells, Cultured; Endothelium, Vascular; Lipid Peroxidation; Nisoldipine; Oxidative Stress

2000