amlodipine has been researched along with nifedipine in 389 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 85 (21.85) | 18.7374 |
| 1990's | 153 (39.33) | 18.2507 |
| 2000's | 87 (22.37) | 29.6817 |
| 2010's | 46 (11.83) | 24.3611 |
| 2020's | 18 (4.63) | 2.80 |
| Authors | Studies |
|---|---|
| Atwal, KS; Gougoutas, JZ; Hedberg, A; Kimball, SD; Malley, MF; Moreland, S; O'Reilly, BC; Rovnyak, GC; Schwartz, J | 1 |
| Alker, D; Campbell, SF; Cross, PE | 1 |
| Atwal, KS; Floyd, DM; Hedberg, A; Moreland, S; O'Reilly, BC; Swanson, BN; Unger, SE | 1 |
| Herbette, LG; Mason, RP; Rhodes, DG | 1 |
| Alker, D; Burges, RA; Campbell, SF; Carter, AJ; Cross, PE; Gardiner, DG | 2 |
| Arrowsmith, JE; Blackburn, KJ; Burges, RA; Campbell, SF; Cross, PE; Gardiner, DG; Stubbs, JK | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Beaumont, K; Smith, DA; van De Waterbeemd, H; Walker, DK | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Einzinger, U; Hoda, JC; Huber, IG; Koschak, A; Obermair, GJ; Sartori, SB; Sinnegger-Brauns, MJ; Striessnig, J; Wild, C | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Reimão, JQ; Scotti, MT; Tempone, AG | 1 |
| Sun, H | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Burburan, PJ; Matubia, VN; Parkin, DW; Ramcharan, SS; Rosario, I; Shea, TA; Stockman, BJ | 1 |
| Beaumont, K; Di, L; Maurer, TS; Smith, DA | 2 |
| Bennis, K; Ducki, S; Lesage, F; Vivier, D | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN | 1 |
| Dong, G; Liu, N; Sheng, C; Tu, J; Wang, Y | 1 |
| Awan, NA; Bamrah, VS; Barry, W; Bennett, T; Canosa, FL; DiBianco, R; Glasser, SP; Kawanishi, DT; Schoomaker, FW; Singh, JB | 1 |
| Beretta-Piccoli, C; Bühler, FR; Donati, L; Heinen, G; Kusch, F | 1 |
| Dalipram, RA; Dusting, GJ; Sobey, CG; Woodman, OL | 1 |
| D'Aprile, N; Faglia, S; Kristodhullo, A; Mondillo, S; Palazzuoli, V | 1 |
| Hagar, JM; Kloner, RA; Newman, LG | 1 |
| Cardillo, R; Castelli, D; Circo, A; Mangiameli, S; Platania, F; Scaccianoce, G | 1 |
| Born, L; Goldmann, S; Stoltefuss, J | 1 |
| Heynen, G | 1 |
| Mason, RP; Moisey, DM; Shajenko, L | 1 |
| Ganzinger, U; Habeler, G; Lenzhofer, R; Pall, H; Tomaschek, A; Ziebart-Schroth, A; Zirm, B | 1 |
| Elliott, HL; Meredith, PA | 2 |
| Simpson, RU; Taylor, JM | 1 |
| Gross, GJ; Pieper, GM | 1 |
| Bruzzone, F; Canale, C; Caponnetto, S; Lonati, A; Malvestiti, FM; Masperone, MA; Terrachini, V | 1 |
| Taylor, SH | 3 |
| Abernethy, DR | 2 |
| Digranes, O; Helland, B; Jordal, O; Lund-Johansen, P; Omvik, P; Stray, T; White, W | 3 |
| Borges, ET; Christeler, P; Guillaume-Gentil, M; Hollenstein, U; Mannhart, M; Waeber, B | 1 |
| Bremner, AD; Fell, PJ; Hosie, J; James, IG; Saul, PA; Taylor, SH | 2 |
| Arena, JP; Chin, S; Kass, RS | 3 |
| Opie, LH | 1 |
| Goncharevskaya, OA; Johns, EJ; Shakhmatova, EI | 1 |
| Garcha, R; Hughes, A; Schachter, M; Sever, P; Thom, SM | 1 |
| Herbette, LG; Mason, RP; Moring, J | 1 |
| Bolger, GT; O'Neill, SK | 1 |
| Heel, RC; Murdoch, D | 1 |
| Gu, XH; Nayler, WG | 4 |
| Gambini, F; Gaviraghi, G; Micheli, D; Quartaroli, M; Tarter, G; Trist, DG | 1 |
| Clozel, JP; Hess, P; Véniant, M; Wolfgang, R | 1 |
| Basco, LK; Le Bras, J | 1 |
| Nayler, WG | 3 |
| Ishiko, J; Munehasu, S; Suzuki, M; Yamanaka, K | 2 |
| Alfiero, R; Cocco, G | 1 |
| Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR | 2 |
| Bäuerle, HD; Seelig, J | 1 |
| Häringer, E; Herrmann, W; Höfling, B; Philippi, M; Pieske, H; Pieske, R | 1 |
| Pedersen, OL; Schroeder, P | 1 |
| Erikssen, J; Lund-Johansen, P; Thaulow, E | 1 |
| Ganz, P; Seelig, J | 1 |
| Cheng, TO | 1 |
| Block, LH; Emmons, LR; Erne, P; Matthys, H; Perruchoud, A; Roth, M | 1 |
| Basco, LK; Clavier, F; Deloron, P; Dubois, B; Gaudin, C; Le Bras, J; Verdier, F | 1 |
| Burges, RA | 2 |
| Tyler, HM | 1 |
| Purcell, H | 1 |
| Ferrari, P; Giachino, D; Heynen, G; Keller, U; Neuner, N; Riesen, W; Shaw, S; Weidmann, P | 1 |
| McGibney, D | 1 |
| Lemmer, B; Mattes, A | 1 |
| Kaplan, NM | 1 |
| Burris, JF; Klein, J; Mroczek, WJ | 1 |
| Varrone, J | 1 |
| Guevara, J; Hernández, O; Hernández, R; Urbina, A; Velasco, M | 1 |
| Beressem, P; Englert, R; Kramar, M; Stafunsky, M; von Manteuffel, E | 1 |
| Armas-de Hernández, MJ; Armas-Padilla, MC; Barragán, O; Carvajal, AR; Guerrero-Pajuelo, J; Hernández, R; Machado-de Alvarado, I | 1 |
| Casabé, H; Dimarco, M; Navarro Estrada, J; Oliveri, R; Saglietti, H | 1 |
| Bruzzone, F; Canale, C; Caponnetto, S; Masperone, MA; Terrachini, V | 1 |
| Grant, P; Gupta, S; Hillis, WS; Hogg, KJ; Hornung, RS; Singh, SP | 2 |
| Dailey, S; Epstein, A; Kay, G; Plumb, V; Vetrovec, GW | 1 |
| Raftery, EB | 1 |
| Meaney, E; Moguel, R; Olvera, R; Samaniego, V | 1 |
| Escudero, J; Hernandez, H | 1 |
| Mosher, SJ; Pollak, PT; Yeung, PK | 1 |
| Fogari, R; Magenta, M; Malacco, E; Tettamanti, F | 1 |
| Catarrasi, C; Chianca, R; Leonetti, G; Ruffilli, MP; Rupoli, L; Zanchetti, A | 1 |
| Guy, S; Jackson, NC; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP; Zezulka, AV | 1 |
| Abernethy, DR; Gutkowska, J; Winterbottom, LM | 1 |
| Lopez, LM; Mehta, JL; Thorman, AD | 1 |
| Hoff, PT; Lucchesi, BR; Tamura, Y | 2 |
| Kloner, RA; Przyklenk, K | 1 |
| Bühler, FR; Erne, P; Kiowski, W; Linder, L | 1 |
| Davies, J; Garsdal, P; Jensen, H | 1 |
| Goldhammer, E; Sharma, SK; Silke, B; Taylor, SH; Verma, SP | 1 |
| Harvengt, C | 1 |
| Blackburn, KJ; Burges, RA; Campbell, SF; Cross, PE; Gardiner, DG; Gwilt, M; Higgins, AJ; Stubbs, JK | 1 |
| Schwartz, JB | 1 |
| Bevan, J; Heptinstall, S | 1 |
| Brobyn, R; Brown, RD; Frishman, WH; Johnson, BF; Reeves, RL; Wombolt, DG | 1 |
| Cocco, G; de Bruijn, B; Tyler, HM | 1 |
| Harris, M; Hossack, KF; Kinnard, DR | 3 |
| Thadani, U | 2 |
| Julius, S | 1 |
| Burges, RA; Carter, AJ; Gardiner, DG | 1 |
| Fleckenstein, A; Fleckenstein-Grün, G; Frey, M; Zorn, J | 2 |
| Arena, JP; DiManno, D; Kass, RS | 1 |
| French, JF; Grupp, G; Grupp, IL; Matlib, MA; Schwartz, A; Van Gorp, C | 1 |
| Beresford, AP; Humphrey, MJ; Macrae, PV; Stopher, DA | 1 |
| Carmody, M; Donohoe, JF; Doyle, GD; Greb, H; Kelly, JG; Laher, MS; Volz, M | 1 |
| Elliott, HL; Faulkner, JK; Meredith, PA; Reid, JL | 1 |
| Abernethy, DR; Gutkowska, J; Lambert, MD | 1 |
| Jeffers, TA; Petrie, JC; Robb, OJ; Scott, AK; Webster, J | 1 |
| Frick, MH; McGibney, D; Tyler, HM | 2 |
| Allenby, KS; Burris, JF; Mroczek, WJ | 1 |
| Maclean, D; Mitchell, ET; Tyler, HM; Walker, P; Wilcox, RG | 2 |
| Lorimer, AR; Smedsrud, T; Tyler, HM; Walker, P | 2 |
| Rofman, BA | 1 |
| Ames, RP; Applegate, WB; Burris, JF; Davidov, ME; Mroczek, WJ; Ram, CV | 1 |
| Chrysant, SG; Glasser, SP; Graves, J; Koehn, DK; Rofman, B | 1 |
| Al-Khawaja, I; Brigden, G; Heber, ME; Raftery, EB | 1 |
| Carmody, M; Donohue, J; Doyle, GD; Greb, H; Laher, M; Volz, M | 1 |
| Alker, D; Beresford, AP; Kobylecki, RJ; Macrae, PV | 1 |
| Chrysant, C; Chrysant, SG; Hitchcock, A; Trus, J | 1 |
| Bevan, J; Glusa, E; Heptinstall, S | 1 |
| Chasseaud, LF; Faulkner, JK; Hayden, ML; Taylor, T | 1 |
| Dailey, S; Epstein, A; Kay, GN; Plumb, V; Vetrovec, G | 1 |
| Jackson, N; Sharma, SK; Silke, B; Taylor, SH; Verma, SP | 1 |
| Lucchesi, BR; Tamura, Y | 1 |
| Glasser, SP; West, TW | 2 |
| Chahine, RA; Feldman, RL; Giles, TD; Nicod, P; Raizner, AE; Weiss, RJ | 1 |
| Casabé, H; Di Marco, M; Estrada, JN; Oliveri, R; Saglietti, H | 1 |
| Carabello, B; Cheitlin, M; Das, S; Deedwania, P; Pasternak, R; Pool, P; Singh, J | 1 |
| Cocco, G; Jackson, N; Lee, P; Taylor, SH | 1 |
| Bekheit, S; Doherty, J; Gorwit, J; Hearan, P; Mather, S; San Fellippo, J; Singh, S; Smith, K; Stein, W; Udhoji, V | 1 |
| Epstein, M; Fischetti, F; Horton, C; Loutzenhiser, RD | 1 |
| Matlib, MA | 1 |
| Bravo, G; Chalant, C; Godfraind, T; Jaumin, P; Mennig, D | 1 |
| Dunlap, ED; Lathrop, DA; Millard, RW; Plowden, JS | 1 |
| Gabel, M; Lathrop, DA; Millard, RW; Plowden, JS; Rämö, MP | 1 |
| Dunlap, ED; Matlib, MA; Millard, RW | 1 |
| Farber, NE; Gross, GJ; Pieper, GM | 2 |
| Sawada, Y; Shimooka, K; Tatematsu, H | 1 |
| Arena, JP; Kass, RS | 1 |
| Campbell, SF; Herbette, LG; Mason, RP; Wang, SD | 1 |
| Burges, RA; Dodd, MG; Gardiner, DG | 1 |
| Osterloh, I | 1 |
| Burges, RA; Carter, AJ; Dodd, MG; Gardiner, DG; Sutton, MR | 1 |
| Beattie, DT; Cunnane, TC; Muir, TC | 1 |
| Chasseaud, LF; Faulkner, JK; McGibney, D; Perry, JL; Taylor, IW | 1 |
| Frais, MA; Jackson, NC; Reynolds, G; Sharma, SK; Silke, B; Taylor, SH; Verma, SP | 1 |
| Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP | 1 |
| Beresford, AP; Macrae, PV; Stopher, DA; Wood, BA | 1 |
| Bauer, JH; Hamory, A; Lau, A; Reams, GP | 1 |
| Jeffers, TA; Petrie, JC; Robb, OJ; Scott, AK; Towler, HM; Webster, J | 1 |
| Johns, EJ | 2 |
| Beresford, AP; Macrae, PV; Stopher, DA | 1 |
| Beresford, AP; Humphrey, MJ; Macrae, PV; McGibney, D; Stopher, DA | 1 |
| Cubeddu, LX; Williams, DM | 1 |
| Bremner, AD; Fell, PJ; Hosie, J; James, GV; Saul, PA; Taylor, SH | 1 |
| Cheng, CP; Little, WC | 1 |
| Ayaori, M; Hosoai, H; Ishikawa, T; Nakamura, H; Nishiwaki, M; Suzukawa, M; Yoshida, H | 1 |
| Hattori, K; Maruyama, K; Nagatomo, T; Qu, YL; Sugiyama, K; Takamizawa, C; Watanabe, K | 1 |
| Erne, P; Heynen, G; Saxenhofer, H; Waeber, B | 2 |
| Abrahamsson, T; Akerblom, B; Nordlander, M; Thalén, P | 1 |
| Bretnall, AE; Clarke, GS | 1 |
| Block, P; De Backer, G; Degaute, JP; Detry, JM | 1 |
| Elliott, HL | 1 |
| Gullotti, D; Iacò, V; Pepe, S; Salerno, L | 1 |
| Huttunen, KR; Knuuttila, ML; Pernu, HE; Tiilikainen, AS | 1 |
| Cheng, CP; Little, WC; Noda, T; Nordlander, M; Ohno, M | 1 |
| Anderson, JA; Davies, J; Laher, MS; Lazarus, JH; Lorimer, AR; Sanghera, S; Taylor, SH | 1 |
| Elliott, HL; Howie, CA; Meredith, PA; Ueda, S | 2 |
| Collins, P; Ferguson, J | 1 |
| Burges, R; Moisey, D | 1 |
| Bewley, AP; Feher, MD; Staughton, RC | 1 |
| Cappuccio, FP; Carney, C; Crane, M; MacGregor, GA; Markandu, ND; Singer, DR | 1 |
| Bachetti, T; Carboni, L; Ferri, S; Ratti, E; Spampinato, S; Van Amsterdam, FT | 1 |
| Cusenza, E; Gaffney, M; Taylor, C | 1 |
| Decrinis, M; Kasper, K; Miyawaki, N; Stark, G; Stark, U; Tritthart, HA | 1 |
| Cheng, CP; Elvelin, L; Little, WC; Nordlander, M | 1 |
| Fujiki, H; Hirano, T; Miyakoda, G; Mori, T; Ohura, M; Orito, K | 1 |
| Detry, JM | 1 |
| Peterlik, M; Pietschmann, P; Redlich, K; Stulc, T | 1 |
| Jorgensen, MG | 1 |
| Kobrin, I; Lacourcière, Y; Massie, BM; Viskoper, R; Woittiez, A | 1 |
| Charlon, V; Kobrin, I; Lindberg, E; Pordy, R | 1 |
| White, CM | 1 |
| Hlawaty, M; Kubler, G; Negrusz-Kawecka, M; Olszowska, M; Salamon, P; Tracz, W; Witkowska, M | 1 |
| Hiroi, Y; Komuro, I; Kudoh, S; Mizuno, T; Nagai, R; Shiojima, I; Yamazaki, T; Yazaki, Y; Zou, Y | 1 |
| Fujimoto, Y; Hamada, T; Hisatome, I; Kaneda, T; Kinugawa, T; Ohtahara, A; Shigemasa, C; Watanabe, M; Yoshida, A | 1 |
| Koen, R; Lacolley, P; Levy, BI; Poitevin, P | 1 |
| Kloner, RA; Levenstein, M; Materson, BJ; Vetrovec, GW | 1 |
| Bernaud, C; Carré, A; Charpentier, JC; Hotton, JM; Lequeuche, B; Mounier-Vehier, C | 1 |
| Archambault, F; Jewell, D; Lacourcière, Y; Lefebvre, J; Poirier, L; Reed, CV | 1 |
| Sesin, J; Tamargo, J | 1 |
| Cartier, P; de Champlain, J; Karas, M; Larochelle, P; Nadeau, R; Nguyen, P; Toal, CB; Wistaff, R | 2 |
| Flack, JM; Hall, WD; Preisser, J; Reed, JW; Yunis, C | 1 |
| Elliott, HL; Feehally, J; Griffin, P; Moore, RJ; Olubodun, JO; Venkat-Raman, G; Wilkinson, R | 1 |
| Seibold, JR; Sturgill, MG | 1 |
| Imai, Y; Ohkubo, T; Omae, T; Sekino, M | 1 |
| Akaike, N; Ishibashi, H; Murai, Y | 1 |
| Calvo, C; Krafcik, MB; Luque-Otero, M; Simonson, DC; Testa, MA; Turner, RR | 1 |
| Hall, WD | 1 |
| Enlow, AM; Halverson, VJ; Kilpatrick, DM; Lower, DL; Montopoli, G; Yamreudeewong, W | 1 |
| Butler, TJ; Ellis, JS; Robertson, P; Seymour, RA; Steele, JG; Thomason, JM | 1 |
| Chierchia, SL; Fragasso, G; Margonato, A; Rossetti, E; Xuereb, M; Xuereb, RG | 1 |
| Gleave, ME; Miyake, H; Nickerson, T; Pollak, M | 1 |
| Karasawa, A; Kobayashi, S; Kosaka, N; Nito, M; Nomura, H; Sonoda, R; Tanaka, H; Yamaguchi, K | 1 |
| Becker, BF; Möbert, J | 1 |
| Cascio, WE; Chowdhury, MK; Crouse, JR; Jollis, JG; Massing, MW; Simpson, RJ; Smith, SC | 1 |
| Baluarte, HJ; Brass, C; Conley, SB; Palmer, J; Polinsky, MS; Silverstein, DM | 1 |
| Fukuo, K; Morimoto, S; Niinobu, T; Ogihara, T; Suhara, T; Yang, J | 1 |
| Nakamoto, H; Okada, H; Shouda, J; Sugahara, S; Suzuki, H | 1 |
| Boomer, S; Campbell, BA; Hull, PS; Irwin, CR; Jamal, S; James, JA; Johnson, RW; Linden, GJ; Marley, JJ; Maxwell, AP; Short, CD; Spratt, H | 1 |
| Marche, P; Stepien, O | 1 |
| Bond, BR; Crawford, FA; Crumbley, AJ; Dorman, BH; Kratz, JM; Multani, MM; Spinale, FG; Zellner, JL | 1 |
| Anderson, R; Hollenberg, NK; Williams, GH | 1 |
| Frishman, W; Glasser, SP; Johnson, MF; Stone, P; White, WB | 1 |
| Chen, D; Lin, J; Wu, K | 1 |
| Beckey, NP; Korman, L; Parra, D | 1 |
| Arbus, GS; Blowey, D; Khattak, S; Koren, G; Lyszkiewicz, DA; Rogan, JW | 1 |
| Kim, D; Kim, HS; Kim, SJ; Ma, KA; Shin, GT | 1 |
| Doherty, J; Korenblat, BM; Lenert, LA; Linde-Zwirble, W; Newbold, R; Smith, ME | 1 |
| Ikeda, M; Ikeda, U; Minota, S; Ohki, R; Shimada, K; Shimpo, M; Takahashi, M; Yamamoto, K | 1 |
| Feng, Z; Messerli, FH; Oparil, S | 1 |
| Matsumori, A; Nunokawa, Y; Sasayama, S | 1 |
| Darné, B; Démolis, JL; Funck-Brentano, C; Jaillon, P; Ragueneau, I; Sao, AB | 1 |
| Alvarez, M; Armas-Hernández, MJ; Armas-Padilla, MC; Chourio, JA; Hernández, RH; López, L; Pacheco, B | 1 |
| Horiai, H; Ohtsuka, M; Oyanagui, Y | 1 |
| Kupper, W; Sauerbrey-Wullkopf, N | 1 |
| Clair, MJ; Gay, DM; Goldberg, A; Hendrick, JW; Jolly, JR; King, MK; McElmurray, JH; Mukherjee, R; Patterson, TM; Spinale, FG | 1 |
| Subramaniam, P; Vijayagopal, P | 1 |
| Faulkner, M; Hilleman, DE; Reyes, AP; Wurdeman, RL | 1 |
| Chan, CH; Chan, HC; Ko, GT | 1 |
| Yanchick, JK | 1 |
| Boari, L; De Dominicis, E; Giusti, C; Kilama, MO; Marchesi, M; Marelli, G; Mattarei, M; Mos, L; Novo, S; Pessina, AC; Pirrelli, A; Santini, M; Santonastaso, M; Semeraro, S; Uslenghi, E | 1 |
| Janssen, BJ; Kam, KL; Smits, JF | 1 |
| Elawad, M; Elliott, HL; Singh, SP; Wilkinson, R | 1 |
| Florea, S; Raicu, M | 1 |
| Ayajiki, K; Fujioka, H; Okamura, T | 1 |
| Fukuda, N; Ikeda, Y; Kanmatsuse, K; Lai, YM; Su, JZ; Suzuki, R; Tahira, Y; Takagi, H | 1 |
| Binggeli, C; Corti, R; Luscher, TF; Noll, G; Sudano, I | 1 |
| Esmore, DS; Rosenfeldt, FL | 1 |
| Ferro, A; Lin, G; Queen, L; Xiao-hong, L; Xu, B | 1 |
| Nussinovitch, N; Peleg, E; Rosenberg, G; Rosenthal, T | 1 |
| Kimura, R; Kusaka, T; Nakajima, M; Uchida, S; Yamada, S | 1 |
| Kritz, H; Oguogho, A; Sinzinger, H; Wolfram, RM | 1 |
| Hirai, M; Iino, S; Kondo, T; Takeshita, K; Tanaka, T | 1 |
| Beilin, LJ; Buranakitjaroen, P; Burke, V; Chen, CY; Dayi, H; Lu, ZR; Morales, D; Ongtengco, I; Puddey, IB; Rahardjo, P; Sanderson, J; Soenarta, AA; Soon, TK; Tan, C; Tanomsup, S; Wu, DJ; Zambahari, DR | 1 |
| Dzhavadova, GK; Mamchur, SE; Nemik, BM; Tepliakov, AT; Vecherskiĭ, IuIu | 1 |
| Szász, G | 1 |
| Campagnola, M; Cominacini, L; Davoli, A; Fratta Pasini, A; Garbin, U; Lo Cascio, V; Nava, C; Pastorino, AM; Rossato, P | 1 |
| von Renteln-Kruse, W | 1 |
| Fujii, M; Hayashi, M; Ishii, C; Maeda, K; Ohnishi, M; Tsutamoto, T; Tsutsui, T; Wada, A | 1 |
| Chan, HC; Ko, GT | 1 |
| Caglar, N; Canberk, A; Deger, N; Demirtas, M; Dortlemez, H; Kes, S; Kiliccioglu, B; Kozan, O; Ovunc, K; Turkoglu, C | 1 |
| Kirakozov, DA; Lopatin, IuM; Statsenko, ME | 1 |
| Pope, J | 1 |
| Inomata, K; Tanaka, H | 1 |
| Shigematsu, M; Takami, T | 1 |
| Boratyńska, M; Klinger, M; Radwan-Oczko, M; Zietek, M | 1 |
| Lee, JD; Mitsuke, Y; Nakano, A; Shimizu, H; Ueda, T; Uzui, H; Yue, H | 1 |
| Bhaskar, HN; Udupa, AL; Udupa, SL | 2 |
| Basile, J | 1 |
| Capuano, A; D'Amico, M; Di Filippo, C; Forgione, A; Lampa, E; Rossi, F | 1 |
| Leonetti, G | 1 |
| Brixius, K; Geissler, HJ; Gross, T; Hekmat, K; Mehlhorn, U; Schwinger, RH; Tossios, P | 1 |
| Hayashi, T; Hirano, Y; Ishikawa, K; Kimura, A; Miyataka, M; Taniguchi, M; Taniwa, T | 1 |
| Karpov, IuA | 1 |
| Chiou, SY; Lai, GW; Lin, G; Lin, LY | 1 |
| Ikeda, J; Matsubara, M; Yao, K | 1 |
| Li, J; Li, QX; Liu, LL; Shao, L; Xia, L | 1 |
| Abe, K; Hanyu, H; Hirao, K; Iwamoto, T; Koizumi, K; Shimizu, S | 1 |
| Furukubo, T; Hirata, S; Ikegawa, S; Izumi, S; Kadowaki, D; Matsunaga, C; Nakanishi, H; Negoro, S; Satoh, M; Yamakawa, T | 1 |
| Relja, M; Telarović, S; Trkulja, V | 1 |
| Ebrahimi, SA; Mahmoudian, M; Rahbr-Roshandel, N; Rouzrokh, A | 1 |
| Itagaki, K; Nakajima, S; Nakamoto, H; Nishida, E; Ryuzaki, M; Sone, M; Suzuki, Y; Yoshimoto, M | 1 |
| Fujiwara, H; Hattori, A; Hiei, K; Io, K; Kato, T; Kawasaki, M; Matsuo, H; Minatoguchi, S; Morita, N; Nishigaki, K; Noda, T; Ojio, S; Ono, H; Sato, H; Segawa, T; Takemura, G; Tanaka, T; Ueno, K; Watanabe, S | 1 |
| Hanyu, H; Hirao, K; Iwamoto, T; Kiuchi, A; Sato, T; Shimizu, S | 1 |
| Hino, E; Kawabe, Y; Nakamura, H; Suzuki, S | 1 |
| Barrios, V; Calderón, A; de la Figuera, M; Escobar, C; Honorato, J; Llisterri, JL; Segura, J | 2 |
| Bucci, C; Juurlink, DN; Mamdani, MM; Tu, JV | 1 |
| Fujikawa, K; Saito, I; Saruta, T | 1 |
| Furuno, M; Higaki, J; Horiuchi, M; Inaba, S; Iwai, M; Kanno, H; Mogi, M; Okayama, H; Senba, I; Tomono, Y | 1 |
| Cox, NH; Robson, RH; Walsh, ML | 1 |
| Albert, DH; Banfor, PN; Cox, BF; Davidsen, SK; Franklin, PH; Fryer, RM; Gintant, GA; Larson, KJ; Noonan, WT; Segreti, JA; Tapang, P; Widomski, DL | 1 |
| Fukuda, M; Ishii, A; Izumi, T; Masuda, T; Moriya, T; Noda, C; Ogura, MN; Tanaka, K; Yamamoto, K; Yonezawa, R | 1 |
| Ao, Y; Li, J; Li, QX; Song, RJ; Tie, CR; Xie, XF | 1 |
| Ando, C; Inoue, Y; Kodama, S; Mihara, H; Miyoshi, K; Niimura, H; Okamura, K; Sumi, S; Tojyo, H; Tsuchiya, Y; Urata, H; Yamanouchi, Y | 1 |
| Matsumori, A; Nishio, R; Nose, Y | 1 |
| Futenma, A; Imai, H; Kimura, Y; Maeda, K; Miura, N; Suga, N; Yamada, H | 1 |
| Goto, T; Nakagawa, K | 1 |
| Kitakaze, M; Liao, YL; Luo, Q; Xi, F; Xuan, WL | 1 |
| Araki, E; Fukuda, K; Ishii, N; Kawada, T; Kim-Mitsuyama, S; Kinoshita, H; Matsumura, T; Miyamura, N; Motoshima, H; Nakao, S; Nishikawa, T; Senokuchi, T; Takeya, M; Tsutsumi, A | 1 |
| Fukumoto, Y; Inoue, Y; Minatoguchi, S; Nishigaki, K; Shimokawa, H; Sueda, S; Urata, H; Yamanouchi, Y; Yasuda, S | 1 |
| Mahmoudian, M; Sepehr-Ara, L; Sepehr-Ara, M | 1 |
| An Haack, K; Bennett, MJ; Li, H; Narayan, SB; Tan, L; Warnock, A | 1 |
| Abe, D; Kubota, T; Morozumi, T; Nakasone, N; Shimizu, T; Yoshie, H | 1 |
| Ceron, CS; Gerlach, RF; Guimaraes, DA; Marçal, DM; Martins-Oliveira, A; Rizzi, E; Tanus-Santos, JE | 1 |
| Aonuma, K; Kuga, K; Lau, AH; Ohtsuka, K; Ohtsuka, M; Watanabe, Y; Xu, DZ | 1 |
| Ishimitsu, T; Kobayashi, N | 1 |
| Elliott, HL; Meredith, PA; Toal, CB | 1 |
| Arias Santos, I; Lago Rivero, N; Paradela Carreiro, A | 1 |
| Chen, LL; He, YS; Li, Y; Li, ZP; Wang, JG; Wei, M; Zeng, WF; Zhang, BW | 1 |
| Choi, H; Choi, NY; Joo Lee, Y; Koh, SH; Lee, EH; Lee, KY; Park, HH; Yu, HJ | 1 |
| Chen, W; Fang, H; Liu, X; Xu, W | 1 |
| Heidari, H; Jouyban, A; Razmi, H | 1 |
| Beydemir, S; Söyüt, H; Türkeş, C | 1 |
| Andrei, AM; Banită, IM; Berbecaru-Iovan, A; Munteanu, C; Pisoschi, CG; Popescu, F; Stănciulescu, CE | 1 |
| Gomes, T; Hellings, C; Huang, A; Juurlink, DN; Mamdani, MM; Paterson, JM; Urbach, DR | 1 |
| Bisenieks, E; Duburs, G; Gall Troselj, K; Krauze, A; Poikans, J; Velena, A; Zarkovic, N | 1 |
| Kotegawa, T; Koya, Y; Machi, Y; Namiki, N; Shobu, Y; Uchida, S | 1 |
| de Vries, C; Haerden, Y; Lins, R | 1 |
| Hoshide, S; Kario, K; Mizuno, H; Tomitani, N | 1 |
| de Souza, RC; Ferreira, DC; Fischer, RG; Gonçalves, LS; Vidal, F | 1 |
| Chakrabarti, SS; Das, P; Gambhir, IS; Kaur, U | 1 |
| Georgianos, PI; Liakopoulos, V; Zebekakis, PE | 1 |
| Dou, Y; Huang, QF; Li, Y; Sheng, CS; Wang, JG; Zheng, MS; Zhu, ZM | 1 |
| Belbachir, N; Kitani, T; Lam, CK; Ma, N; Rhee, JW; Shrestha, R; Tian, L; Wnorowski, A; Wu, JC | 1 |
| Blom, MT; Davis, RP; de Boer, A; Eroglu, TE; Folke, F; Gislason, GH; Mohr, GH; Souverein, PC; Tan, HL; Torp-Pedersen, C; van den Brink, L; Verkerk, AO; Wissenberg, M | 1 |
| Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V | 1 |
| Liu, J | 1 |
| Eriksdotter, M; Garcia-Ptacek, S; Kalar, I; Kramberger, MG; Schwertner, E; Secnik, J; von Euler, M; Winblad, B; Xu, H | 1 |
| Miyashita, Y; Morikawa, S; Nakagawa, T; Nasu, M | 1 |
| Chen, LL; Li, Y; Wang, JG; Xie, JH; Xu, SK; Zeng, WF | 1 |
| Agu, CE; Chukwu, IJ; Nnedu, EB; Uchendu, IK | 1 |
| Bohra, GK; Chhabra, V; Kumar, D; Midha, N; Reddy, SC | 1 |
| Du, P; Mei, Z; Qin, S; Shi, S; Yin, J | 1 |
| Huang, CC; Lee, HW; Leu, HB; Lin, YJ | 1 |
| Hirakawa, H; Ito, M; Josaka, R; Kikuchi, D; Miura, R; Obara, T; Okada, K; Suzuki, N; Tokunaga, M; Usui, K | 1 |
| Ankrah, D; Hollingworth, SA; Okeke, CC; Ruiz, F; Thacher, E; Uzochukwu, BSC | 1 |
| Song, J; Wang, X; Wu, J; Zhang, R; Zhu, J | 1 |
| Hojnacki, D; Podolsky, R; Schaller, B; Sternberg, Z; Tian, M; Yu, J | 1 |
| Kawasaki, N; Mizuno, Y; Nakamura, T; Nishida, K; Ogata, F; Takegami, M; Uematsu, Y; Yanae, M | 1 |
| Elton, A; Kwa, M; Singh, J | 1 |
| Hirata, T; Ishii, T; Kokuba, S; Nakamura, K; Shiohira, H; Tayag, JCS | 1 |
| Tchernev, G | 1 |
41 review(s) available for amlodipine and nifedipine
| Article | Year |
|---|---|
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes.
Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship | 1991 |
Property-based design: optimization of drug absorption and pharmacokinetics.
Topics: Animals; Biological Transport; Blood Proteins; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane; Drug Design; Eye; Humans; Intestinal Absorption; Models, Biological; Models, Molecular; Nasal Mucosa; Pharmaceutical Preparations; Pharmacokinetics; Prodrugs; Skin Absorption | 2001 |
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship | 2016 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Emerging New Targets for the Treatment of Resistant Fungal Infections.
Topics: Antifungal Agents; Drug Resistance, Fungal; Humans; Molecular Targeted Therapy; Mycoses | 2018 |
Clinical pharmacokinetics of amlodipine.
Topics: Absorption; Amlodipine; Angina Pectoris; Biological Availability; Calcium Channel Blockers; Drug Interactions; Half-Life; Humans; Hypertension; Liver; Nifedipine; Tissue Distribution | 1992 |
Profiles of calcium antagonists in cardiovascular disease with special reference to second-generation agents and amlodipine.
Topics: Amlodipine; Antihypertensive Agents; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cardiovascular Diseases; Drug Interactions; Humans; Nifedipine | 1991 |
Amlodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in cardiovascular disease.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Nifedipine | 1991 |
[Amlodipine].
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Humans; Hypertension; Nifedipine | 1991 |
[Amlodipin (Norvasc). A new calcium antagonist with long half-life].
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Half-Life; Humans; Hypertension; Nifedipine | 1991 |
New drugs for hypertension--variations on old themes.
Topics: Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dihydropyridines; Doxazosin; Humans; Hypertension; Isradipine; Nifedipine; Prazosin; Verapamil | 1991 |
Amlodipine: a once daily calcium antagonist.
Topics: Amlodipine; Animals; Antihypertensive Agents; Biological Availability; Blood Pressure; Calcium Channel Blockers; Half-Life; Humans; Natriuresis; Nifedipine | 1991 |
Amlodipine: an effective once-daily antihypertensive agent.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hypertension; Longitudinal Studies; Nifedipine | 1991 |
The clinical consequences of the absorption, distribution, metabolism and excretion of amlodipine.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Nifedipine | 1991 |
The efficacy of amlodipine in the management of ischaemic heart disease.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Humans; Nifedipine; Randomized Controlled Trials as Topic | 1991 |
The pharmacological profile of amlodipine in relation to ischaemic heart disease.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cats; Coronary Disease; Dogs; Mice; Muscle Contraction; Nifedipine; Rats | 1991 |
Amlodipine in the treatment of hypertension.
Topics: Amlodipine; Blood Pressure Determination; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Hypertension; Kidney; Nifedipine | 1991 |
A review of amlodipine in myocardial ischaemia.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Nifedipine | 1991 |
Cardioprotective effects of amlodipine on ischemia and reperfusion in two experimental models.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cats; Coronary Disease; Dogs; In Vitro Techniques; Myocardial Reperfusion Injury; Nifedipine | 1990 |
Progress in cardioprotection: the role of calcium antagonists.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cardiovascular Diseases; Dogs; Humans; Nifedipine | 1990 |
Amlodipine in hypertension: an overview of the clinical dossier.
Topics: Amlodipine; Calcium Channel Blockers; Humans; Hypertension; Nifedipine | 1988 |
The pharmacokinetic profile of amlodipine.
Topics: Administration, Oral; Aging; Amlodipine; Angina Pectoris; Animals; Biological Availability; Calcium Channel Blockers; Cimetidine; Digoxin; Drug Interactions; Half-Life; Humans; Injections, Intravenous; Kidney Diseases; Liver Cirrhosis; Nifedipine | 1989 |
Pharmacologic profile of amlodipine.
Topics: Administration, Oral; Amlodipine; Anesthesia; Animals; Antihypertensive Agents; Binding Sites; Calcium Channel Blockers; Calcium Channels; Hemodynamics; Humans; Kidney; Muscle, Smooth, Vascular; Nifedipine | 1989 |
The efficacy of amlodipine in myocardial ischemia.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blockers; Coronary Disease; Dose-Response Relationship, Drug; Humans; Nifedipine | 1989 |
Vascular versus myocardial effects of calcium antagonists.
Topics: Amlodipine; Animals; Dogs; Felodipine; Heart Failure; Hemodynamics; Humans; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Pressoreceptors; Ventricular Function, Left | 1994 |
Unique pharmacologic properties of amlodipine.
Topics: Amlodipine; Animals; Aorta; Calcium Channel Blockers; Delayed-Action Preparations; Dogs; Hypertension; In Vitro Techniques; Kidney; Muscle Contraction; Myocardial Reperfusion Injury; Nifedipine; Portal Vein; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1994 |
Vascular selective calcium entry blockers in the treatment of cardiovascular disorders: focus on felodipine.
Topics: Amlodipine; Calcium Channel Blockers; Coronary Disease; Felodipine; Heart Failure; Hemodynamics; Humans; Hypertension; Myocardial Contraction; Nifedipine; Vasodilation | 1995 |
Calcium channel blockers in left ventricular dysfunction or congestive heart failure.
Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Felodipine; Heart Failure; Humans; Nicardipine; Nifedipine; Ventricular Dysfunction, Left; Verapamil | 1997 |
Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients.
Topics: Amlodipine; Calcium Channel Blockers; Cause of Death; Cerebrovascular Disorders; Clinical Trials as Topic; Delayed-Action Preparations; Female; Follow-Up Studies; Heart Failure; Hemorrhage; Humans; Hypertension; Incidence; Male; Middle Aged; Myocardial Infarction; Nifedipine; Prospective Studies; Safety; Survival Rate; Treatment Outcome; United States | 1998 |
[Clinical pharmacokinetics of calcium antagonists].
Topics: Amlodipine; Calcium Channel Blockers; Humans; Nifedipine | 1997 |
Circadian heart rate response to chronotherapy versus conventional therapy in patients with hypertension and myocardial ischemia.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Blood Pressure; Calcium Channel Blockers; Chronotherapy; Delayed-Action Preparations; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Randomized Controlled Trials as Topic; Retrospective Studies; Verapamil | 2000 |
Raynaud's phenomenon (primary).
Topics: Amlodipine; Diltiazem; Humans; Nafronyl; Nicardipine; Nifedipine; Raynaud Disease; Vasodilator Agents | 2003 |
The role of existing and newer calcium channel blockers in the treatment of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nitrendipine; Treatment Outcome; Verapamil | 2004 |
[Ischemic heart disease combined with hypertension: peculiarities of course and selection of therapy].
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Controlled Clinical Trials as Topic; Enalapril; Female; Humans; Hypertension; Indoles; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Perindopril; Placebos; Risk Factors; Surveys and Questionnaires; Time Factors; Vasodilator Agents; Verapamil | 2005 |
Prognostic effects of calcium channel blockers in patients with vasospastic angina--a meta-analysis.
Topics: Amlodipine; Angina Pectoris; Asian People; Calcium Channel Blockers; Coronary Vasospasm; Dihydropyridines; Diltiazem; Humans; Nifedipine; Prognosis; Treatment Outcome | 2010 |
Long-acting dihydropyridine calcium-channel blockers and sympathetic nervous system activity in hypertension: a literature review comparing amlodipine and nifedipine GITS.
Topics: Amlodipine; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Nifedipine; Sympathetic Nervous System | 2012 |
1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues-Model Compounds Targeting Oxidative Stress.
Topics: Amlodipine; Animals; Antioxidants; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cattle; Dihydropyridines; Epithelial Cells; Humans; Hydrogen; Lipoproteins, LDL; Mice; Microsomes; Mitochondria; Niacinamide; Nifedipine; Nitrobenzenes; Oxidants; Oxidative Stress; Piperazines | 2016 |
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease; Female; Fetal Growth Retardation; Furosemide; Gestational Age; Humans; Hypertension; Incidence; Infant, Small for Gestational Age; Ketanserin; Methyldopa; Network Meta-Analysis; Nifedipine; Perinatal Death; Pindolol; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Premature Birth; Severity of Illness Index | 2020 |
Nifedipine or amlodipine? The choice for hypertension during pregnancy: a systematic review and meta-analysis.
Topics: Amlodipine; Female; Humans; Hypertension; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome | 2022 |
Bibliometric analysis of research trends and characteristics of drug-induced gingival overgrowth.
Topics: Amlodipine; Anticonvulsants; Bibliometrics; Calcium Channel Blockers; Cyclosporine; Gingival Overgrowth; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin | 2022 |
Comparison of various calcium antagonist on vasospastic angina: a systematic review.
Topics: Adult; Amlodipine; Calcium; Calcium Channel Blockers; Coronary Vasospasm; Diltiazem; Humans; Nifedipine; Observational Studies as Topic; Quality of Life | 2023 |
116 trial(s) available for amlodipine and nifedipine
| Article | Year |
|---|---|
Amlodipine combined with beta blockade for chronic angina: results of a multicenter, placebo-controlled, randomized double-blind study.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Nitroglycerin | 1992 |
Amlodipine versus nifedipine retard in the treatment of chronic ischemic heart disease.
Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Chronic Disease; Coronary Disease; Delayed-Action Preparations; Female; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Single-Blind Method | 1992 |
[Effectiveness and tolerance of amlodipine in treatment of patients with mild to moderate hypertension. Results of a long-term study with a new calcium antagonist].
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Drug Evaluation; Female; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Nifedipine | 1992 |
[A comparison between amlodipine and nifedipine retard in patients with essential arterial hypertension].
Topics: Adult; Aged; Amlodipine; Analysis of Variance; Calcium Channel Blockers; Delayed-Action Preparations; Drug Evaluation; Drug Tolerance; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Single-Blind Method | 1992 |
Amlodipine in post-infarction angina.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Circadian Rhythm; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nifedipine | 1992 |
Amlodipine compared to nitrendipine in hypertensive patients: the effects on toleration in relationship to the onset of action.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nifedipine; Nitrendipine | 1992 |
Comparison of early side effects with amlodipine and nifedipine retard in hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Single-Blind Method | 1992 |
A double-blind dose-response study of amlodipine in patients with stable angina pectoris.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Coronary Circulation; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Nifedipine; Nitroglycerin | 1991 |
A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine.
Topics: Adult; Amlodipine; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Nifedipine; Potassium | 1991 |
Effects of amlodipine on urinary sodium excretion, renin-angiotensin-aldosterone system, atrial natriuretic peptide and blood pressure in essential hypertension.
Topics: Aldosterone; Amlodipine; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Female; Humans; Male; Middle Aged; Nifedipine; Renin; Renin-Angiotensin System; Sodium | 1991 |
[Therapy of mild to moderate hypertension. Efficacy and tolerance of Amlodipine in comparison with the combination nifedipine/mefruside].
Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hypertension; Male; Mefruside; Middle Aged; Nifedipine | 1991 |
Amlodipine: an effective once-daily antihypertensive agent.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hypertension; Longitudinal Studies; Nifedipine | 1991 |
A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Determination; Calcium Channel Blockers; Double-Blind Method; Female; Headache; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nifedipine; Urination Disorders | 1991 |
A study of the efficacy and safety of amlodipine for the treatment of hypertension in general practice.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Edema; Female; Headache; Humans; Hypertension; Male; Middle Aged; Nifedipine; Skin Diseases | 1991 |
A double-blind, parallel, comparative evaluation of amlodipine against captopril in the monotherapeutic treatment of mild and moderate essential hypertension: interim results.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1991 |
Amlodipine compared to nitrendipine for the treatment of mild-to-moderate hypertension.
Topics: Amlodipine; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Vasodilation | 1991 |
Anti-ischaemic properties of amlodipine, a new calcium antagonist, in patients with severe coronary artery disease: a prospective trial.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Nitroglycerin; Prospective Studies | 1991 |
Open comparative study to assess the efficacy and safety of two calcium antagonists, amlodipine and diltiazem, in the treatment of symptomatic myocardial ischaemia.
Topics: Amlodipine; Angina Pectoris; Coronary Disease; Diltiazem; Hemodynamics; Humans; Middle Aged; Nifedipine; Nitroglycerin | 1991 |
Efficacy and tolerability of amlodipine in patients with mild-to-moderate hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Heart Rate; Humans; Hypertension; Middle Aged; Nifedipine | 1991 |
Clinical evaluation of amlodipine, a new long-acting calcium antagonist, in mild and moderate hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Heart Rate; Humans; Hypertension; Middle Aged; Nifedipine | 1991 |
Twenty-four-hour blood pressure control using once daily treatment with a calcium antagonist or an angiotensin converting enzyme inhibitor.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nifedipine | 1991 |
Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension.
Topics: Amlodipine; Blood Pressure; Blood Pressure Monitors; Calcium Channel Blockers; Exercise; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors | 1990 |
Effects of amlodipine on blood pressure, heart rate, catecholamines, lipids and responses to adrenergic stimulus.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Catecholamines; Double-Blind Method; Exercise; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged; Nifedipine; Single-Blind Method | 1990 |
Arterial vasodilator effects of the dihydropyridine calcium antagonist amlodipine alone and in combination with verapamil in systemic hypertension.
Topics: Amlodipine; Calcium Channel Blockers; Drug Therapy, Combination; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitroprusside; Regional Blood Flow; Vasodilator Agents; Verapamil | 1990 |
Amlodipine with enalapril therapy in moderate-severe essential hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1990 |
An exercise hemodynamic comparison of verapamil, diltiazem, and amlodipine in coronary artery disease.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Diltiazem; Exercise; Hemodynamics; Humans; Middle Aged; Nifedipine; Prospective Studies; Rest; Verapamil | 1990 |
Effects of amlodipine on steady-state digoxin concentrations and renal digoxin clearance.
Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Digoxin; Drug Interactions; Electrocardiography; Humans; Kidney; Male; Nifedipine | 1988 |
A randomized placebo-controlled comparison of amlodipine and atenolol in mild to moderate systemic hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Atenolol; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged; Nifedipine; Patient Compliance; Random Allocation | 1988 |
Multicenter placebo-controlled comparison of amlodipine and atenolol in mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Atenolol; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation | 1988 |
Amlodipine in angina pectoris: effect on maximal and submaximal exercise performance.
Topics: Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Exercise Test; Female; Humans; Male; Middle Aged; Nifedipine; Physical Endurance | 1988 |
Amlodipine--a once-daily calcium antagonist in the treatment of angina pectoris: a parallel dose-response placebo-controlled study.
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Dose-Response Relationship, Drug; Exercise Test; Humans; Middle Aged; Nifedipine | 1988 |
A comparison of the disposition of single oral doses of amlodipine in young and elderly subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amlodipine; Blood Pressure; Calcium Channel Blockers; Female; Half-Life; Humans; Male; Middle Aged; Nifedipine | 1988 |
Once-daily amlodipine in the treatment of mild to moderate hypertension.
Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Middle Aged; Nifedipine; Random Allocation | 1988 |
Amlodipine: a double-blind evaluation of the dose-response relationship in mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation | 1988 |
A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure in hypertensive patients.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Nifedipine; Pulse; Random Allocation; Time Factors | 1988 |
A double-blind crossover comparison of amlodipine and placebo added to captopril in moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Calcium Channel Blockers; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation | 1988 |
Comparison of amlodipine and verapamil in the treatment of mild to moderate hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pulse; Random Allocation; Verapamil | 1988 |
Long-term open evaluation of amlodipine versus hydrochlorothiazide in patients with essential hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Pulse; Random Allocation | 1988 |
Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation; Time Factors | 1988 |
Safety and efficacy of amlodipine added to hydrochlorothiazide therapy in essential hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Nifedipine; Random Allocation | 1989 |
A dose-response study of amlodipine in mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Hypertension; Middle Aged; Nifedipine; Random Allocation | 1989 |
Antihypertensive effectiveness of amlodipine in combination with hydrochlorothiazide.
Topics: Alanine Transaminase; Amlodipine; Aspartate Aminotransferases; Calcium Channel Blockers; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Supination | 1989 |
A comparison of amlodipine, verapamil and placebo in the treatment of mild to moderate hypertension. Amlodipine Study Group.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Placebos; Pulse; Random Allocation; Verapamil | 1989 |
Pharmacodynamics of amlodipine: hemodynamic effects and antianginal efficacy after atrial pacing.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cardiac Catheterization; Cardiac Pacing, Artificial; Coronary Disease; Electrocardiography; Female; Hemodynamics; Humans; Male; Middle Aged; Nifedipine | 1989 |
Clinical safety and efficacy of once-daily amlodipine for chronic stable angina pectoris.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Drug Administration Schedule; Exercise Test; Humans; Nifedipine; Nitroglycerin | 1989 |
Efficacy and safety of amlodipine in vasospastic angina: an interim report of a multicenter, placebo-controlled trial. The Investigators of Study 160.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Vasospasm; Edema; Humans; Leg; Nifedipine; Nitroglycerin | 1989 |
Antiischemic properties of amlodipine, a new calcium antagonist, in patients with severe coronary artery disease: a prospective trial.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Prospective Studies | 1989 |
Double-blind crossover comparison of amlodipine at three dose levels and placebo in chronic stable angina.
Topics: Aged; Amlodipine; Angina Pectoris; Chronic Disease; Double-Blind Method; Exercise Test; Female; Humans; Male; Middle Aged; Nifedipine; Placebos; Time Factors | 1989 |
A four-week double-blind, placebo-controlled, parallel dose-response study of amlodipine in patients with stable exertional angina pectoris.
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Nifedipine; Nitroglycerin; Physical Exertion; Placebos; Time Factors | 1989 |
Amlodipine: a once-daily calcium antagonist in the treatment of angina pectoris--a parallel dose-response, placebo-controlled study. The Amlodipine Study Group.
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Exercise Test; Humans; Middle Aged; Nifedipine; Placebos; Time Factors | 1989 |
Amlodipine in angina pectoris: effect on maximal and submaximal exercise performance.
Topics: Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Exercise; Exercise Test; Female; Humans; Middle Aged; Nifedipine; Nitroglycerin; Physical Endurance | 1989 |
Amlodipine versus nadolol in patients with stable angina pectoris.
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Drug Administration Schedule; Exercise Test; Humans; Middle Aged; Nadolol; Nifedipine; Time Factors | 1989 |
The safety of amlodipine.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Edema; Fatigue; Flushing; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Nifedipine | 1989 |
A haemodynamic dose finding study with a new slow-calcium channel blocker (amlodipine) in coronary artery disease.
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Exercise Test; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Random Allocation; Vascular Resistance | 1986 |
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.
Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nisoldipine; Prospective Studies; Random Allocation; Verapamil | 1987 |
Once daily amlodipine in the treatment of mild to moderate hypertension.
Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation | 1987 |
Endurance testing for evaluation of antianginal therapy with amlodipine, a calcium channel blocking agent.
Topics: Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Evaluation Studies as Topic; Exercise Test; Female; Humans; Male; Middle Aged; Nifedipine; Oxygen Consumption; Physical Endurance | 1988 |
Clinical safety and efficacy of once-a-day amlodipine for chronic stable angina pectoris.
Topics: Aged; Amlodipine; Angina Pectoris; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Random Allocation | 1988 |
Amlodipine pharmacokinetics in healthy volunteers.
Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Half-Life; Humans; Male; Nifedipine; Random Allocation | 1988 |
Side effects of dihydropyridine therapy: comparison of amlodipine and nifedipine retard.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Blood Pressure; Delayed-Action Preparations; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Single-Blind Method | 1993 |
Use of drugs with more than a twenty-four-hour duration of action.
Topics: Aged; Amlodipine; Cross-Over Studies; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Patient Compliance; Prospective Studies | 1994 |
Patient compliance and therapeutic coverage: comparison of amlodipine and slow release nifedipine in the treatment of hypertension. The Belgian Collaborative Study Group.
Topics: Amlodipine; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Patient Compliance | 1995 |
[Time of drug intake in hypertension and angina pectoris. A controlled monitoring study].
Topics: Aged; Amlodipine; Angina Pectoris; Confidence Intervals; Cross-Over Studies; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Patient Compliance; Prospective Studies | 1994 |
Double-blind comparison of amlodipine and nifedipine retard in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Aging; Amlodipine; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1994 |
Long-acting calcium antagonists: amlodipine versus nifedipine gastrointestinal therapeutic system (GITS).
Topics: Adult; Amlodipine; Angiotensin II; Blood Pressure; Delayed-Action Preparations; Digestive System; Double-Blind Method; Humans; Male; Nifedipine; Norepinephrine; Time Factors | 1993 |
Double-blind comparison between nifedipine and amlodipine for the treatment of essential hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Double-Blind Method; Female; Hormones; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1993 |
Harmonic regression analysis of the effect of drug treatment on the diurnal rhythm of blood pressure and angina.
Topics: Amlodipine; Angina Pectoris; Blood Pressure; Circadian Rhythm; Double-Blind Method; Humans; Hypertension; Models, Statistical; Nifedipine; Regression Analysis | 1993 |
Early side-effects of antihypertensive therapy: comparison of amlodipine and nifedipine retard.
Topics: Adult; Aged; Amlodipine; Delayed-Action Preparations; Dizziness; Double-Blind Method; Edema; Female; Flushing; Headache; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors | 1993 |
Patient compliance and therapeutic coverage: amlodipine versus nifedipine SR in the treatment of hypertension and angina: interim results. Steering Committee and Cardiologists and General Practitioners involved in the Belgium Multicentre Study on Patient
Topics: Amlodipine; Angina Pectoris; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Patient Compliance | 1994 |
Mibefradil in the treatment of systemic hypertension: comparative studies with other calcium antagonists.
Topics: Adult; Aged; Amlodipine; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Edema; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Leg; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes | 1997 |
Safety of mibefradil, a new once-a-day, selective T-type calcium channel antagonist.
Topics: Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Chronic Disease; Drug Administration Schedule; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Hypertension; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes | 1997 |
[Comparative study to assess the efficacy and adverse effects of amlodipine and nifedipine retard in patients with stable exertional angina and hypertension].
Topics: Aged; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Drug Administration Schedule; Exercise Test; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitroglycerin; Vasodilator Agents | 1997 |
Evaluation of changes in sympathetic nerve activity and heart rate in essential hypertensive patients induced by amlodipine and nifedipine.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Delayed-Action Preparations; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Single-Blind Method; Sympathetic Nervous System | 1998 |
Compliance and antihypertensive efficacy of amlodipine compared with nifedipine slow-release.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Patient Compliance; Treatment Outcome | 1998 |
Comparative effects of felodipine ER, amlodipine and nifedipine GITS on 24 h blood pressure control and trough to peak ratios in mild to moderate ambulatory hypertension: a forced titration study.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Delayed-Action Preparations; Felodipine; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Outpatients; Treatment Outcome | 1998 |
Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Time Factors; Vasodilator Agents | 1998 |
Comparison of the efficacy of dihydropyridine calcium channel blockers in African American patients with hypertension. ISHIB Investigators Group. International Society on Hypertension in Blacks.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black People; Blood Pressure; Body Weight; Calcium Channel Blockers; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Severity of Illness Index; Time Factors; Treatment Outcome | 1998 |
Renal and haemodynamic effects of amlodipine and nifedipine in hypertensive renal transplant recipients.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Cyclosporine; Female; Follow-Up Studies; Glomerular Filtration Rate; Graft Rejection; Humans; Hypertension; Kidney; Kidney Transplantation; Male; Middle Aged; Nifedipine; Renal Plasma Flow; Single-Blind Method | 1998 |
Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Drug Administration Schedule; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Single-Blind Method; Systole; Vasodilator Agents | 1998 |
A perspective on the calcium antagonists in blacks (CAB) trial.
Topics: Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Male; Nifedipine; Time Factors; White People | 1998 |
Evaluation of amlodipine dosing for conversion of nifedipine extended-release to amlodipine in the treatment of hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Drug Costs; Humans; Hypertension; Male; Middle Aged; Nifedipine; Vasodilator Agents | 1999 |
Use of calcium-channel blockers in pediatric renal transplant recipients.
Topics: Adolescent; Amlodipine; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Retrospective Studies; Treatment Outcome | 1999 |
Medical therapy, symptoms, and the distress the cause: relation to quality of life in patients with angina pectoris and/or hypertension.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Quality of Life; Treatment Outcome; Verapamil | 2000 |
[The effect of amlodipine, nifedipine and perindopril on insulin sensitivity and blood lipid of patients with essential hypertension].
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hypertension; Insulin Resistance; Lipids; Male; Middle Aged; Nifedipine; Perindopril | 1998 |
A randomized prospective crossover trial of amlodipine in pediatric hypertension.
Topics: Adolescent; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Child; Cross-Over Studies; Felodipine; Female; Humans; Hypertension; Male; Nifedipine; Patient Compliance; Prospective Studies | 2000 |
Comparison of efficacy and side effects of combination therapy of angiotensin-converting enzyme inhibitor (benazepril) with calcium antagonist (either nifedipine or amlodipine) versus high-dose calcium antagonist monotherapy for systemic hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Single-Blind Method | 2000 |
Comparison of sympathetic modulation induced by single oral doses of mibefradil, amlodipine, and nifedipine in healthy volunteers.
Topics: Administration, Oral; Adult; Aldosterone; Amlodipine; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Electrocardiography; Epinephrine; Hemodynamics; Humans; Male; Mibefradil; Nifedipine; Sympathetic Nervous System | 2001 |
Comparative effects of amlodipine and nifedipine GITS during treatment and after missing two doses.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Digestive System; Double-Blind Method; Drug Delivery Systems; Female; Humans; Male; Middle Aged; Nifedipine; Office Visits; Therapeutic Equivalency; Time Factors; Treatment Refusal | 2001 |
[Amlodipine versus nifedipine retard. A randomized double-blind comparative study on long-term efficacy and safety of amlodipine and nifedipine retard in the monotherapy of chronic stable angina pectoris].
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Data Interpretation, Statistical; Delayed-Action Preparations; Double-Blind Method; Electrocardiography; Exercise Test; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifedipine; Patient Compliance; Time Factors; Vasodilator Agents | 2001 |
Blood pressure reduction and tolerability of amlodipine versus nifedipine retard in Chinese patients with type 2 diabetes mellitus and hypertension: a randomized 1-year clinical trial.
Topics: Administration, Oral; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Treatment Outcome | 2001 |
Efficacy, tolerability and influence on "quality of life" of nifedipine GITS versus amlodipine in elderly patients with mild-moderate hypertension.
Topics: Aged; Aged, 80 and over; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Humans; Hypertension; Middle Aged; Nifedipine; Quality of Life; Therapeutic Equivalency | 2001 |
Persistence of antihypertensive efficacy after missed doses: comparison of amlodipine and nifedipine gastrointestinal therapeutic system.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Digestive System; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors; Treatment Outcome | 2002 |
Effects of chronic calcium channel blockade on sympathetic nerve activity in hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Double-Blind Method; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Muscles; Nifedipine; Norepinephrine; Sympathetic Nervous System; Verapamil | 2002 |
A comparative crossover evaluation of amlodipine and nifedipine GITS before and after a missed dose: 48-h blood pressure profiles.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Digestive System; Dose-Response Relationship, Drug; Humans; Hypertension; Multivariate Analysis; Nifedipine; Patient Compliance; Treatment Outcome | 2002 |
Persistence of the antihypertensive efficacy of amlodipine and nifedipine GITS after two 'missed doses': a randomised, double-blind comparative trial in Asian patients.
Topics: Amlodipine; Antihypertensive Agents; Asia, Southeastern; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Hypertension; Nifedipine | 2002 |
[Postoperative spasm of mammary-coronary grafts and possibilities of its correction by dihydropyridine calcium antagonists nifedipine and amlodipine].
Topics: Amlodipine; Blood Flow Velocity; Calcium Channel Blockers; Coronary Circulation; Diastole; Humans; Internal Mammary-Coronary Artery Anastomosis; Male; Middle Aged; Nifedipine; Postoperative Complications; Systole; Time Factors; Treatment Outcome; Vasodilator Agents | 2002 |
Restoration of nocturnal dip in blood pressure is associated with improvement in left ventricular ejection fraction. A 1-year clinical study comparing the effects of amlodipine and nifedipine retard on ambulatory blood pressure and left ventricular systol
Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; China; Circadian Rhythm; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Recovery of Function; Stroke Volume; Treatment Outcome; Ventricular Function, Left | 2003 |
Treatment of mild-to-moderate hypertension with calcium channel blockers: a multicentre comparison of once-daily nifedipine GITS with once-daily amlodipine.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Drug Administration Schedule; Drug Tolerance; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Safety | 2003 |
A comparative assessment of the duration of action of amlodipine and nifedipine GITS in normotensive subjects.
Topics: Adult; Amlodipine; Angiotensin II; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Norepinephrine; Vasodilator Agents | 1993 |
Effects of calcium channel antagonists on left ventricular hypertrophy and diastolic function in patients with essential hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diastole; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine | 2003 |
Effects of nilvadipine and amlodipine in patients with mild to moderate essential hypertension: a double blind, prospective, randomised clinical trial.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Electrocardiography; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Nifedipine; Placebos; Prospective Studies | 2005 |
Favourable effects of nilvadipine on cognitive function and regional cerebral blood flow on SPECT in hypertensive patients with mild cognitive impairment.
Topics: Aged; Amlodipine; Antihypertensive Agents; Brain; Cerebrovascular Circulation; Cognition Disorders; Humans; Hypertension; Nifedipine; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2007 |
Interaction between activated VD3 and Ca channel blockers in patients undergoing hemodialysis.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcitriol; Calcium Channel Blockers; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Hydroxycholecalciferols; Nifedipine; Renal Dialysis | 2007 |
Restless legs syndrome in hemodialysis patients: association with calcium antagonists. A preliminary report.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Cross-Sectional Studies; Female; Humans; Logistic Models; Male; Middle Aged; Nifedipine; Odds Ratio; Renal Dialysis; Restless Legs Syndrome; Retrospective Studies | 2007 |
Crossover study of amlodipine versus nifedipine CR with home blood pressure monitoring via cellular phone: internet-mediated open-label crossover trial of calcium channel blockers for hypertension (i-TECHO trial).
Topics: Adult; Aged; Amlodipine; Blood Pressure Determination; Calcium Channel Blockers; Cell Phone; Cross-Over Studies; Female; Humans; Hypertension; Internet; Male; Middle Aged; Nifedipine; Pulse; Telemedicine | 2007 |
Nilvadipine prevents cognitive decline of patients with mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Cognition Disorders; Disease Progression; Female; Humans; Male; Nifedipine; Tomography, Emission-Computed, Single-Photon | 2007 |
High doses of lercanidipine are better tolerated than other dihydropyridines in hypertensive patients with metabolic syndrome: results from the TOLERANCE study.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Cross-Sectional Studies; Dihydropyridines; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Nifedipine | 2008 |
Tolerability of high doses of lercanidipine versus high doses of other dihydropyridines in daily clinical practice: the TOLERANCE Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Sectional Studies; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Logistic Models; Male; Middle Aged; Nifedipine; Primary Health Care; Spain; Vasodilation | 2008 |
Influence of nifedipine coat-core and amlodipine on systemic arterial stiffness modulated by sympathetic and parasympathetic activity in hypertensive patients.
Topics: Adult; Aged; Amlodipine; Arteries; Blood Pressure; Calcium Channel Blockers; Female; Heart; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Parasympathetic Nervous System; Sympathetic Nervous System | 2009 |
Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment.
Topics: Aged; Amlodipine; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Nifedipine; Tetrazoles | 2009 |
Valsartan/amlodipine compared to nifedipine GITS in patients with hypertension inadequately controlled by monotherapy.
Topics: Adult; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Asian People; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Tetrazoles; Treatment Outcome | 2013 |
The efficacy and safety of arotinolol combined with a different calcium channel blocker in the treatment of Chinese patients with essential hypertension: a one-year follow-up study.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Asian People; Blood Pressure; Calcium Channel Blockers; China; Circadian Rhythm; Drug Therapy, Combination; Essential Hypertension; Felodipine; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propanolamines; Treatment Outcome | 2014 |
Comparison of ambulatory blood pressure-lowering effects of higher doses of different calcium antagonists in uncontrolled hypertension: the Calcium Antagonist Controlled-Release High-Dose Therapy in Uncontrolled Refractory Hypertensive Patients (CARILLON)
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium; Calcium Channel Blockers; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Tetrazoles | 2017 |
A randomized controlled trial on the blood pressure-lowering effect of amlodipine and nifedipine-GITS in sustained hypertension.
Topics: Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Case-Control Studies; China; Circadian Rhythm; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Safety; Treatment Outcome | 2019 |
A comparative study for the effects of nifedipine GITS and amlodipine besylate administrated in daytime or at nighttime on recovery of blood pressure rhythm and arterial stiffness in the young and middle-aged subjects with non-dipper hypertension (NARRAS)
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Middle Aged; Nifedipine; Vascular Stiffness | 2020 |
Effects of the valsartan/amlodipine combination and nifedipine gastrointestinal therapeutic system monotherapy on brachial pulse pressure and radial augmentation index in hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nifedipine; Tetrazoles; Treatment Outcome; Valsartan | 2021 |
233 other study(ies) available for amlodipine and nifedipine
| Article | Year |
|---|---|
Dihydropyrimidine calcium channel blockers. 4. Basic 3-substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic acid esters. Potent antihypertensive agents.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Crystallization; Hypertension; Male; Molecular Structure; Nifedipine; Piperidines; Pyrimidines; Rabbits; Rats; Rats, Inbred SHR; Stereoisomerism; Structure-Activity Relationship; Vasodilation; X-Ray Diffraction | 1992 |
Long-acting dihydropyridine calcium antagonists. 6. Structure-activity relationships around 4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-2-[(2-hydroxyethoxy)methyl]-5 -(methoxycarbonyl)-6-methyl-1,4-dihydropyridine.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Heart Rate; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship | 1991 |
Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Male; Pyrimidines; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Structure-Activity Relationship | 1991 |
Long-acting dihydropyridine calcium antagonists. 4. Synthesis and structure-activity relationships for a series of basic and nonbasic derivatives of 2-[(2-aminoethoxy)methyl]-1,4-dihydropyridine calcium antagonists.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Chemical Phenomena; Chemistry; Dihydropyridines; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Time Factors; Vasodilator Agents | 1990 |
Long-acting dihydropyridine calcium antagonists. 5. Synthesis and structure-activity relationships for a series of 2-[[(N-substituted-heterocyclyl)ethoxy]methyl]-1,4-dihydropyridine calcium antagonists.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Guinea Pigs; Imidazoles; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardium; Organ Specificity; Rats; Structure-Activity Relationship; Time Factors | 1990 |
Long-acting dihydropyridine calcium antagonists. 1. 2-Alkoxymethyl derivatives incorporating basic substituents.
Topics: Amlodipine; Animals; Biological Assay; Biological Availability; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Dogs; Guinea Pigs; Hemodynamics; Kinetics; Male; Nifedipine; Pyridines; Rats; Vasoconstriction | 1986 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms.
Topics: Amino Acid Motifs; Animals; Brain; Calcium Channels, L-Type; Dihydropyridines; Female; Gene Expression; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Protein Isoforms | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Dose-Response Relationship, Drug; Molecular Structure; N-Glycosyl Hydrolases; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Rabeprazole; Structure-Activity Relationship; Trichomonas vaginalis | 2014 |
Volume of Distribution in Drug Design.
Topics: Drug Design; Half-Life; Pharmacokinetics | 2015 |
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain | 2016 |
Relevance of Half-Life in Drug Design.
Topics: Biological Availability; Delayed-Action Preparations; Drug Design; Half-Life; Humans; Pharmaceutical Preparations; Tissue Distribution | 2018 |
Antihypertensive mechanism of amlodipine in essential hypertension: role of pressor reactivity to norepinephrine and angiotensin II.
Topics: Adult; Amlodipine; Angiotensin II; Antihypertensive Agents; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Electrolytes; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Renin-Angiotensin System | 1992 |
Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinol.
Topics: Acetylcholine; Allopurinol; Amlodipine; Animals; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Nifedipine; Nitroglycerin; Propranolol | 1992 |
[The association of amlodipine with isosorbide-5-mononitrate in the treatment of ischemic-hypertensive cardiopathy].
Topics: Adult; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Coronary Disease; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Vasodilator Agents | 1992 |
Effects of amlodipine on myocardial infarction, infarct expansion, and ventricular geometry in the rat.
Topics: Amlodipine; Analysis of Variance; Animals; Calcium Channel Blockers; Female; Heart; Heart Ventricles; Hemodynamics; Myocardial Contraction; Myocardial Infarction; Myocardium; Nifedipine; Rats; Rats, Inbred Strains; Regression Analysis; Vasodilator Agents | 1992 |
Determination of the absolute configuration of the active amlodipine enantiomer as (-)-S: a correction.
Topics: Amlodipine; Molecular Conformation; Nifedipine; Stereoisomerism; X-Ray Diffraction | 1992 |
[Amlodipine: pharmacokinetic and pharmacodynamic profile of a calcium antagonist with prolonged effect].
Topics: Amlodipine; Angina Pectoris; Animals; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Humans; Nifedipine; Structure-Activity Relationship | 1992 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
[24-hour protection and control: a new era of calcium antagonists. Amlodipine provides 24 hours of efficacy and safety].
Topics: Amlodipine; Calcium Channel Blockers; Circadian Rhythm; Coronary Disease; Humans; Hypertension; Nifedipine; Safety; Time Factors | 1992 |
Inhibition of cancer cell growth by calcium channel antagonists in the athymic mouse.
Topics: Amlodipine; Animals; Breast Neoplasms; Calcium; Calcium Channel Blockers; Cell Division; Culture Media; Diltiazem; DNA, Neoplasm; Drug Screening Assays, Antitumor; Mice; Mice, Nude; Nifedipine; Tumor Cells, Cultured; Verapamil | 1992 |
Beneficial actions of amlodipine in the multiple-stunned canine myocardium.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Dogs; Energy Metabolism; Female; Heart; Hemodynamics; Male; Nifedipine; Reperfusion | 1992 |
Pharmacokinetics and pharmacodynamics of amlodipine.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Half-Life; Humans; Hypertension; Nifedipine | 1992 |
Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitors; Calcium Channel Blockers; Exercise; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors | 1992 |
Block of L-type calcium channels by charged dihydropyridines. Sensitivity to side of application and calcium.
Topics: Amlodipine; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Diffusion; Dihydropyridines; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Myocardium; Nifedipine; Nisoldipine; Receptors, Nicotinic | 1991 |
The influence of amlodipine and verapamil on ion and water transport in the nephron, skin and urinary bladder of amphibians.
Topics: Amlodipine; Animals; Capillaries; Kidney; Kidney Tubules; Male; Nephrons; Nifedipine; Perfusion; Rana temporaria; Salamandridae; Skin; Sodium; Urinary Bladder; Vasopressins; Verapamil; Water | 1991 |
Amlodipine in cardiovascular disease: the need for 24-hour protection and control. Proceedings of a meeting, Hong Kong, February 17, 1990.
Topics: Amlodipine; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Nifedipine | 1991 |
Amlodipine inhibition of alpha-agonist induced contraction in human resistance vessels.
Topics: Adrenergic alpha-Agonists; Amlodipine; Azepines; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nifedipine; Norepinephrine; Phenylephrine; Skin; Vasoconstriction | 1991 |
A molecular model involving the membrane bilayer in the binding of lipid soluble drugs to their receptors in heart and brain.
Topics: 1,2-Dipalmitoylphosphatidylcholine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Brain; Cholesterol; Dihydropyridines; Gels; Lipid Bilayers; Membranes; Models, Chemical; Models, Molecular; Myocardium; Nifedipine; Rats; Receptors, Drug; Sarcolemma; Solubility | 1990 |
The effects of dihydropyridine calcium channel modulators on pentylenetetrazole convulsions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Male; Mice; Nifedipine; Nimodipine; Seizures | 1990 |
(-)[3H]amlodipine binding to rat cardiac membranes.
Topics: Amlodipine; Animals; Female; Gallopamil; Hydrogen-Ion Concentration; In Vitro Techniques; Isradipine; Kinetics; Membranes; Myocardium; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains; Stereoisomerism; Temperature | 1991 |
The hemodynamic effects of lacidipine in anesthetized dogs: comparison with nitrendipine, amlodipine, verapamil, and diltiazem.
Topics: Amlodipine; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Stroke Volume; Vascular Resistance; Verapamil | 1991 |
Hemodynamic profile of Ro 40-5967 in conscious rats: comparison with diltiazem, verapamil, and amlodipine.
Topics: Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Hemodynamics; Male; Mibefradil; Nifedipine; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Verapamil | 1991 |
Plasmodium falciparum: in vitro drug interaction between chloroquine and enantiomers of amlodipine.
Topics: Amlodipine; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Chloroquine; Drug Resistance; Drug Synergism; Erythrocytes; Molecular Structure; Nifedipine; Plasmodium falciparum; Stereoisomerism | 1991 |
Vascular injury: mechanisms and manifestations.
Topics: Amlodipine; Animals; Aorta, Thoracic; Arteriosclerosis; Calcium; Calcium Channel Blockers; Cardiomegaly; Cholesterol, Dietary; Hypertension; In Vitro Techniques; Male; Myocardium; Nifedipine; Organ Size; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1991 |
[Effect of amlodipine, a new calcium antagonist on isolated blood vessels].
Topics: Amlodipine; Animals; Aorta; Blood Vessels; Calcium Channel Blockers; Calcium Chloride; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Rabbits; Rats; Rats, Inbred Strains | 1991 |
[Antihypertensive effects of amlodipine, a new calcium antagonist].
Topics: Administration, Oral; Amlodipine; Animals; Calcium Channel Blockers; Dogs; Dose-Response Relationship, Drug; Hypertension; Hypertension, Renal; Male; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1991 |
Interaction of charged and uncharged calcium channel antagonists with phospholipid membranes. Binding equilibrium, binding enthalpy, and membrane location.
Topics: Amlodipine; Calcium Channel Blockers; Magnetic Resonance Spectroscopy; Membrane Lipids; Membrane Potentials; Nifedipine; Nimodipine; Phospholipids; Phosphorus Isotopes; Thermodynamics | 1991 |
Nonclassical hydrophobic effect in membrane binding equilibria.
Topics: Amlodipine; Calorimetry; Dibucaine; Fluorescent Dyes; Lipid Bilayers; Liposomes; Membrane Lipids; Naphthalenesulfonates; Nifedipine; Phosphatidylcholines; Solubility; Tetraphenylborate; Thermodynamics; Water | 1991 |
All calcium channel blockers are not alike.
Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Heart Failure; Humans; Nifedipine | 1991 |
Ca(2+)-channel blockers modulate expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and low density lipoprotein receptor genes stimulated by platelet-derived growth factor.
Topics: Amlodipine; Calcium Channel Blockers; Cell Division; Cell Line; Cell Membrane; DNA Replication; Fibroblasts; Gene Expression; Genes; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Nifedipine; Nitrendipine; Platelet-Derived Growth Factor; Receptors, LDL; RNA, Messenger; Skin; Transcription, Genetic; Verapamil | 1991 |
In vitro and in vivo potentiation of chloroquine against malaria parasites by an enantiomer of amlodipine.
Topics: Amlodipine; Animals; Chloroquine; Drug Synergism; Erythrocytes; Female; Malaria, Falciparum; Mice; Nifedipine; Plasmodium; Plasmodium falciparum; Stereoisomerism | 1991 |
The unique binding properties of amlodipine: a long-acting calcium antagonist.
Topics: Amlodipine; Animals; Binding Sites; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Nifedipine; Rats; Rats, Inbred Strains; Time Factors | 1991 |
New calcium antagonists.
Topics: Amlodipine; Calcium Channel Blockers; Humans; Nifedipine | 1991 |
Unaltered insulin sensitivity during calcium channel blockade with amlodipine.
Topics: Adult; Amlodipine; Blood Glucose; Calcium Channel Blockers; Humans; Insulin; Lipoproteins; Male; Nifedipine; Prospective Studies; Reference Values | 1991 |
Effects of amlodipine on circadian rhythms in blood pressure, heart rate, and motility: a telemetric study in rats.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Heart Rate; Male; Motor Activity; Nifedipine; Rats; Rats, Inbred Strains | 1991 |
Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Drug Administration Schedule; Female; Heart; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Physical Exertion; Stroke Volume; Time Factors; Vascular Resistance | 1991 |
The effects of the calcium antagonist amlodipine on blood pressure and platelet aggregation in hypertensive patients.
Topics: Amlodipine; Calcium Channel Blockers; Drug Administration Schedule; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
Vascular and myocardial effects of amlodipine: an overview.
Topics: Amlodipine; Animals; Arteriosclerosis; Binding Sites; Calcium Channel Blockers; Cardiomegaly; Cerebrovascular Disorders; Coronary Disease; Myocardial Reperfusion Injury; Nifedipine; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Survival Rate; Time Factors | 1991 |
Anti-anginal efficacy of intravenous amlodipine assessed by means of atrial pacing.
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cardiac Pacing, Artificial; Electrocardiography; Humans; Injections, Intravenous; Nifedipine | 1991 |
Haemodynamic and electrophysiological effects of amlodipine, a new long-acting calcium antagonist.
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Electrocardiography; Hemodynamics; Humans; Injections, Intravenous; Middle Aged; Nifedipine | 1991 |
Circadian variation in blood pressure: considerations for therapy.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Calcium Channel Blockers; Catecholamines; Circadian Rhythm; Humans; Hypertension; Monitoring, Physiologic; Nifedipine | 1991 |
Liquid chromatography assay for amlodipine: chemical stability and pharmacokinetics in rabbits.
Topics: Acetates; Acetonitriles; Amlodipine; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Light; Nifedipine; Rabbits | 1991 |
Acute, chronic and postwithdrawal antihypertensive and renal effects of amlodipine in hypertensive patients.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Kidney; Nifedipine; Potassium; Renal Circulation; Sodium | 1991 |
Haemodynamic and radionuclide effects of amlodipine in coronary artery disease.
Topics: Adult; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Exercise; Heart Function Tests; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Pulmonary Circulation; Radionuclide Imaging; Vascular Resistance | 1990 |
Effects of amlodipine, a long-acting dihydropyridine calcium antagonist in aging hypertension: pharmacodynamics in relation to disposition.
Topics: Administration, Oral; Adult; Aged; Aging; Amlodipine; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Catecholamines; Female; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Nifedipine; Renin-Angiotensin System | 1990 |
Protecting the vasculature: an eye toward the future.
Topics: Amlodipine; Animals; Arteries; Arteriosclerosis; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Female; Hypertension; Male; Nifedipine; Rabbits; Rats; Rats, Inbred Strains; Survival Rate | 1990 |
Drugs recently released in Belgium. Amlodipine besilate--encainide.
Topics: Amlodipine; Anilides; Anti-Arrhythmia Agents; Calcium Channel Blockers; Encainide; Humans; Nifedipine | 1990 |
Calcium channel blocking properties of amlodipine in vascular smooth muscle and cardiac muscle in vitro: evidence for voltage modulation of vascular dihydropyridine receptors.
Topics: Action Potentials; Amlodipine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Depression, Chemical; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Kinetics; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 1987 |
How can we inhibit 5-HT-induced platelet aggregation and why should we bother?
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Amlodipine; Female; Humans; Male; Middle Aged; Nifedipine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Serotonin Antagonists; Verapamil | 1988 |
Calcium antagonists in cardiovascular disease: rationale for 24-hour action. Proceedings of an official satellite symposium and papers on amlodipine presented at the 25th Anniversary International Symposium on Calcium Antagonists in Hypertension. Basel, S
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Nifedipine | 1988 |
Natriuretic activity of amlodipine, diltiazem, and nitrendipine in saline-loaded anesthetized dogs.
Topics: Amlodipine; Anesthesia; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Female; Hemodynamics; Natriuresis; Nifedipine; Nitrendipine; Sodium; Time Factors | 1988 |
Particular antihypertensive profile of amlodipine administered orally to Okamoto rats (SHRs) and NaCl-loaded salt-sensitive Dahl rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium Chloride; Time Factors | 1988 |
The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload.
Topics: Aging; Amlodipine; Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiomegaly; Coronary Disease; Hypertension; Male; Myocardial Reperfusion; Myocardium; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1988 |
Block of heart calcium channels by amlodipine: influence of drug charge on blocking activity.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Electrochemistry; Guinea Pigs; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Myocardium; Nifedipine | 1988 |
Vasodilatory action of amlodipine on rat aorta, pig coronary artery, human coronary artery, and on isolated Langendorff rat heart preparations.
Topics: Amlodipine; Animals; Aorta, Thoracic; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Heart; Heart Rate; Humans; In Vitro Techniques; Male; Myocardial Contraction; Nifedipine; Rats; Species Specificity; Swine; Vasodilator Agents | 1988 |
The metabolism and pharmacokinetics of amlodipine in humans and animals.
Topics: Adult; Amlodipine; Animals; Biological Availability; Blood Proteins; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dogs; Humans; Male; Mice; Nifedipine; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity | 1988 |
Pharmacokinetics of amlodipine in renal impairment.
Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Female; Half-Life; Humans; Kidney Diseases; Male; Middle Aged; Nifedipine; Time Factors | 1988 |
Amlodipine in elderly hypertensive patients: pharmacokinetics and pharmacodynamics.
Topics: Adult; Aged; Aging; Amlodipine; Blood Pressure; Calcium Channel Blockers; Female; Half-Life; Hormones; Humans; Hypertension; Male; Nifedipine | 1988 |
24 h blood pressure control with the once daily calcium antagonist, amlodipine.
Topics: Adolescent; Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Male; Middle Aged; Monitoring, Physiologic; Nifedipine; Time Factors | 1989 |
Pharmacokinetics of amlodipine in renal impairment.
Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Female; Half-Life; Humans; Kidney Diseases; Male; Middle Aged; Nifedipine | 1989 |
Biotransformation of amlodipine. Identification and synthesis of metabolites found in rat, dog and human urine/confirmation of structures by gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry.
Topics: Amlodipine; Animals; Biotransformation; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dihydropyridines; Dogs; Gas Chromatography-Mass Spectrometry; Humans; Nifedipine; Rats; Species Specificity | 1989 |
Verapamil is a potent inhibitor of 5-HT-induced platelet aggregation.
Topics: Adenosine Diphosphate; Amlodipine; Calcium Channel Blockers; Collagen; Diltiazem; Epinephrine; Humans; In Vitro Techniques; Nifedipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin Antagonists; Verapamil | 1989 |
Absorption of amlodipine unaffected by food. Solid dose equivalent to solution dose.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Capsules; Food; Humans; Male; Nifedipine; Solutions | 1989 |
Circadian variation in myocardial ischemia: the 24-hour antianginal effect of amlodipine. Proceedings of a symposium. Monte Carlo, Monaco, April 7, 1989.
Topics: Amlodipine; Calcium Channel Blockers; Circadian Rhythm; Coronary Disease; Humans; Nifedipine | 1989 |
Hemodynamic and electrophysiologic effects of amlodipine, a new long-acting calcium antagonist: preliminary observations.
Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Electrophysiology; Female; Heart; Hemodynamics; Humans; Male; Middle Aged; Nifedipine | 1989 |
A hemodynamic comparison of verapamil, diltiazem, and amlodipine in coronary artery disease.
Topics: Amlodipine; Calcium Channel Blockers; Coronary Disease; Diltiazem; Female; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Physical Exertion; Rest; Verapamil | 1989 |
Cardioprotective effects of amlodipine in the ischemic-reperfused heart.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cats; Dogs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Oxygen Consumption; Vascular Resistance | 1989 |
A symposium: Pharmacology and therapeutic considerations of amlodipine, a new 1,4-dihydropyridine calcium antagonist. November 5, 1988, Paris, France. Proceedings.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Humans; Nifedipine | 1989 |
Cardioprotective effects of amlodipine in the ischemic-reperfused heart.
Topics: Amlodipine; Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Cats; Compliance; Coronary Circulation; Electrophysiology; Female; Heart; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Rest | 1989 |
Effects of amlodipine on renal hemodynamics.
Topics: Amlodipine; Angiotensin II; Animals; Blood Vessels; Calcium Channel Blockers; Forecasting; Hemodynamics; In Vitro Techniques; Male; Microcirculation; Nifedipine; Perfusion; Potassium Chloride; Rats; Rats, Inbred Strains; Renal Circulation; Vasoconstriction | 1989 |
Amlodipine, a new 1,4-dihydropyridine calcium antagonist with a particularly strong antihypertensive profile.
Topics: Amlodipine; Animals; Antihypertensive Agents; Arteriosclerosis; Calcium; Calcium Channel Blockers; Dihydropyridines; Heart; In Vitro Techniques; Isoproterenol; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocardium; Nifedipine; Rabbits; Rats; Retinal Artery; Swine; Vasoconstriction | 1989 |
Relaxation of potassium chloride-induced contractions by amlodipine and its interaction with the 1,4-dihydropyridine-binding site in pig coronary artery.
Topics: Amlodipine; Animals; Binding Sites; Calcium Channel Blockers; Coronary Vessels; Dihydropyridines; Isradipine; Nifedipine; Oxadiazoles; Potassium Chloride; Sarcolemma; Stereoisomerism; Swine; Vasoconstriction; Vasodilation | 1989 |
Inhibition by amlodipine of activity evoked in isolated human coronary arteries by endothelin, prostaglandin F2 alpha and depolarization.
Topics: Amlodipine; Calcium Channel Blockers; Coronary Vessels; Dinoprost; Electrophysiology; Endothelins; Endothelium, Vascular; Humans; In Vitro Techniques; Nifedipine; Papillary Muscles; Peptides; Potassium; Vasoconstriction; Vasodilation | 1989 |
Amlodipine pretreatment and the ischemic heart.
Topics: Acidosis; Adenosine Triphosphate; Amlodipine; Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Phosphocreatine; Rats; Rats, Inbred Strains; Reperfusion; Time Factors | 1989 |
Hemodynamic and electrophysiologic effects of amlodipine, a new calcium channel blocker.
Topics: Amlodipine; Animals; Autonomic Nerve Block; Calcium Channel Blockers; Dogs; Electrophysiology; Female; Heart Conduction System; Hemodynamics; Male; Nifedipine; Time Factors | 1989 |
Amlodipine, a long-acting calcium antagonist drug reduces ischemia-induced ventricular conduction delay in pig hearts.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Electrophysiology; Heart; Heart Conduction System; Heart Ventricles; Nifedipine; Reperfusion; Swine; Time Factors | 1989 |
Protection of regional mechanics and mitochondrial oxidative phosphorylation by amlodipine in transiently ischemic myocardium.
Topics: Amlodipine; Animals; Biomechanical Phenomena; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Dogs; Electrophysiology; Female; Hemodynamics; Male; Mitochondria, Heart; Nifedipine; Oxidative Phosphorylation; Time Factors | 1989 |
Effects of amlodipine on myocardial ischemia-reperfusion injury in dogs.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Dogs; Energy Metabolism; Female; Heart; Hemodynamics; Male; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Ultrasonography | 1989 |
Effect of amlodipine on myocardial functional and metabolic recovery following coronary occlusion and reperfusion in dogs.
Topics: Adenine Nucleotides; Amlodipine; Animals; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Dogs; Female; Heart; Hemodynamics; Male; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Phosphates; Phosphocreatine; Water | 1989 |
Analysis of amlodipine in serum by a sensitive high-performance liquid chromatographic method with amperometric detection.
Topics: Amlodipine; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Humans; Male; Nifedipine | 1989 |
Modulation of calcium channels by charged and neutral dihydropyridines.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electric Conductivity; Electrochemistry; Hydrogen-Ion Concentration; Ions; Membrane Potentials; Nifedipine; Protons | 1989 |
Influence of pHo on calcium channel block by amlodipine, a charged dihydropyridine compound. Implications for location of the dihydropyridine receptor.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; Nifedipine; Receptors, Nicotinic | 1989 |
Comparison of location and binding for the positively charged 1,4-dihydropyridine calcium channel antagonist amlodipine with uncharged drugs of this class in cardiac membranes.
Topics: Amlodipine; Animals; Calcium Channels; Cations; Crystallography; Dogs; In Vitro Techniques; Kinetics; Lipid Bilayers; Membrane Lipids; Molecular Structure; Myocardium; Nifedipine; Sarcolemma; Solubility; Structure-Activity Relationship | 1989 |
Cellular electrophysiology of amlodipine: probing the cardiac L-type calcium channel.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels; Cell Separation; Electrophysiology; Hydrogen-Ion Concentration; Intracellular Membranes; Ions; Kinetics; Myocardium; Nifedipine; Time Factors | 1989 |
The hemodynamic properties of amlodipine in anesthetised and conscious dogs: comparison with nitrendipine and influence of beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Amlodipine; Anesthesia; Animals; Calcium Channel Blockers; Cardiac Output; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Male; Nifedipine; Nitrendipine; Propranolol; Time Factors; Vascular Resistance | 1989 |
Effects of calcium channel antagonists on action potential conduction and transmitter release in the guinea-pig vas deferens.
Topics: Action Potentials; Amlodipine; Animals; Calcium Channel Blockers; Cobalt; Guinea Pigs; Hypogastric Plexus; In Vitro Techniques; Male; Muscle, Smooth; Neural Conduction; Neuromuscular Junction; Neurotransmitter Agents; Nifedipine; Tetrodotoxin; Vas Deferens | 1986 |
The pharmacokinetics of amlodipine in healthy volunteers after single intravenous and oral doses and after 14 repeated oral doses given once daily.
Topics: Administration, Oral; Adult; Amlodipine; Calcium Channel Blockers; Drug Administration Schedule; Half-Life; Humans; Injections, Intravenous; Kinetics; Male; Nifedipine | 1986 |
Analysis of amlodipine in human plasma by gas chromatography.
Topics: Amlodipine; Calcium Channel Blockers; Calibration; Chromatography, Gas; Half-Life; Humans; Nifedipine | 1987 |
Amlodipine therapy corrects renal abnormalities encountered in the hypertensive state.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Body Fluids; Calcium Channel Blockers; Drug Evaluation; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Nifedipine; Prospective Studies; Renal Circulation; Vascular Resistance | 1987 |
A study of the action of amlodipine on adrenergically regulated sodium handling by the kidney in normotensive and hypertensive rats.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Hypertension; Kidney; Kidney Concentrating Ability; Kidney Tubules; Male; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium; Sympathetic Nervous System; Water | 1988 |
Metabolism of amlodipine in the rat and the dog: a species difference.
Topics: Administration, Oral; Amlodipine; Animals; Chromatography, Thin Layer; Dogs; Feces; Mass Spectrometry; Nifedipine; Rats; Species Specificity | 1988 |
Metabolism and kinetics of amlodipine in man.
Topics: Administration, Oral; Adult; Amlodipine; Biological Availability; Chromatography; Feces; Humans; Injections, Intravenous; Male; Metabolic Clearance Rate; Nifedipine | 1988 |
A study of the renal actions of amlodipine in the normotensive and spontaneously hypertensive rat.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Hypertension; Kidney Tubules; Kidney Tubules, Proximal; Male; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renal Circulation | 1988 |
Amlodipine and captopril in moderate-severe essential hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation | 1988 |
Effects of Ca-antagonists on oxidative susceptibility of low density lipoprotein (LDL).
Topics: Adult; Amlodipine; Apolipoproteins; Calcium Channel Blockers; Electrophoresis, Agar Gel; Fatty Acids; Female; Humans; Hypertension; In Vitro Techniques; Lipids; Lipoproteins, LDL; Male; Middle Aged; Nifedipine; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances | 1995 |
Residual inhibition in density of [3H]isradipine binding sites in rat brain membrane pretreated with amlodipine.
Topics: Amlodipine; Animals; Binding Sites; Brain; Calcium Channel Blockers; Dihydropyridines; Isradipine; Male; Nifedipine; Oxadiazoles; Radioligand Assay; Rats; Rats, Wistar | 1995 |
Vascular versus myocardial selectivity of dihydropyridine calcium antagonists as studied in vivo and in vitro.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Felodipine; Heart; Heart Rate; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Organ Specificity; Rats; Rats, Inbred SHR | 1995 |
Investigation and optimisation of the use of micellar electrokinetic chromatography for the analysis of six cardiovascular drugs.
Topics: Amlodipine; Atenolol; Cardiovascular Agents; Chromatography; Diltiazem; Electrochemistry; Hydrogen-Ion Concentration; Kinetics; Micelles; Nicardipine; Nifedipine; Osmosis; Sodium Dodecyl Sulfate; Verapamil | 1995 |
Vascular reactivity: a measurement of calcium channel blockade.
Topics: Amlodipine; Angiotensin II; Blood Pressure; Dihydropyridines; Humans; Infusions, Intravenous; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Vasoconstriction | 1995 |
[Gingival hyperplasia induced by amlodipine].
Topics: Adult; Amlodipine; Calcium Channel Blockers; Gingival Hyperplasia; Humans; Hypertension; Male; Nifedipine | 1995 |
Drug-induced gingival overgrowth and class II major histocompatibility antigens.
Topics: Adult; Amlodipine; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Felodipine; Female; Gingiva; Gingival Diseases; Histocompatibility Testing; HLA-DR Antigens; Humans; Kidney Transplantation; Male; Nifedipine; Retrospective Studies; Risk Factors | 1994 |
Comparison of effects of dihydropyridine calcium antagonists on left ventricular systolic and diastolic performance.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Felodipine; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Myocardial Contraction; Nifedipine | 1994 |
Photodistributed nifedipine-induced facial telangiectasia.
Topics: Adult; Amlodipine; Facial Dermatoses; Female; Humans; Male; Middle Aged; Nifedipine; Photosensitivity Disorders; Telangiectasis | 1993 |
Erythema multiforme following substitution of amlopidine for nifedipine.
Topics: Amlodipine; Erythema Multiforme; Humans; Male; Middle Aged; Nifedipine | 1993 |
Ca2+ channel blocking activity of lacidipine and amlodipine in A7r5 vascular smooth muscle cells.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cytosol; Dihydropyridines; Female; Fura-2; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Pregnancy; Rats; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1993 |
Effects of semotiadil, a novel Ca2+ channel antagonist, on the electrical activity of Langendorff-perfused guinea pig hearts in comparison with diltiazem, amlodipine and nifedipine.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Electrocardiography; Female; Guinea Pigs; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Nifedipine; Thiazoles | 1995 |
Venodilator effects of pranidipine, a 1,4-dihydropyridine Ca2+ channel antagonist, in rats: comparison with nifedipine and amlodipine.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Dihydropyridines; Injections, Intravenous; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Venous Pressure | 1997 |
Comparative study on the effect of calcium channel blockers on basal and parathyroid hormone-induced bone resorption in vitro.
Topics: Amlodipine; Animals; Bone Resorption; Calcium Channel Blockers; Gallopamil; Mice; Nifedipine; Organ Culture Techniques; Parathyroid Hormone; Parietal Bone; Specific Pathogen-Free Organisms; Verapamil | 1997 |
Prevalence of amlodipine-related gingival hyperplasia.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Dental Plaque Index; Female; Gingival Hyperplasia; Humans; Information Systems; Male; Middle Aged; Nifedipine; Patient Compliance; Prevalence; Smoking; Time Factors | 1997 |
Efficient inhibition of the development of cardiac remodeling by a long-acting calcium antagonist amlodipine.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiomegaly; Collagen; Heart; Hypertension; Male; Myocardium; Myosin Heavy Chains; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1998 |
Different effects of calcium antagonists on fluid filtration of large arteries and albumin permeability in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Capillary Permeability; Carotid Arteries; Edema; Heart Rate; Hemodynamics; Hypertension; Male; Mibefradil; Nifedipine; Rats; Rats, Inbred SHR; Serum Albumin; Tetrahydronaphthalenes | 1998 |
Rational use of calcium-channel antagonists in Raynaud's phenomenon.
Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Humans; Isradipine; Nicardipine; Nifedipine; Raynaud Disease | 1998 |
Differential effects of antihypertensive drugs with differing pharmacological properties on the basal ambulatory blood pressure. Japanese Ambulatory Pressure-ANtihypertensive Effects SEarching study group.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Humans; Lisinopril; Male; Middle Aged; Nifedipine; Office Visits; Systole | 1998 |
Effect of nilvadipine on the voltage-dependent Ca2+ channels in rat hippocampal CA1 pyramidal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Flunarizine; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar | 1998 |
Quality of life and calcium channel blockade with nifedipine GITS versus amlodipine in hypertensive patients in Spain. Gastrointestinal Therapeutic System.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Double-Blind Method; Drug Delivery Systems; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Quality of Life; Spain | 1998 |
Prevalence of gingival overgrowth induced by calcium channel blockers: a community-based study.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Analysis of Variance; Calcium Channel Blockers; Dental Plaque Index; Diltiazem; Dose-Response Relationship, Drug; England; Female; Gingival Hyperplasia; Gingivitis; Humans; Logistic Models; Male; Middle Aged; Nifedipine; Periodontal Index; Prevalence; Sex Ratio; Time Factors | 1999 |
Long-term preservation of left ventricular function in medically treated patients with coronary artery disease and persistent exercise-induced ischemia.
Topics: Aged; Amlodipine; Anti-Arrhythmia Agents; Atenolol; Cardiovascular Agents; Coronary Disease; Data Interpretation, Statistical; Diastole; Diltiazem; Drug Therapy, Combination; Echocardiography; Electrocardiography, Ambulatory; Exercise Test; Follow-Up Studies; Humans; Middle Aged; Nifedipine; Nitrates; Stroke Volume; Systole; Time Factors; Vasodilator Agents; Ventricular Function, Left | 1999 |
Castration-induced apoptosis of androgen-dependent shionogi carcinoma is associated with increased expression of genes encoding insulin-like growth factor-binding proteins.
Topics: Amlodipine; Animals; Apoptosis; Calcium Channel Blockers; Calcium Signaling; Carcinoma; Gene Expression Regulation, Neoplastic; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 5; Male; Mice; Mice, Inbred Strains; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nifedipine; Orchiectomy; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Testosterone | 1999 |
[Effects of benidipine hydrochloride (Coniel) on blood pressure, heart rate and plasma norepinephrine concentration in spontaneously hypertensive rats].
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Heart Rate; Hypertension; Male; Nifedipine; Norepinephrine; Rats; Rats, Inbred SHR | 1999 |
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relationship, Drug; Energy Metabolism; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Purines; Pyruvates | 1999 |
Calcium channel blockers and mortality in elderly patients with myocardial infarction.
Topics: Aged; Aged, 80 and over; Amlodipine; Bepridil; Calcium Channel Blockers; Diltiazem; Female; Humans; Logistic Models; Male; Myocardial Infarction; Nifedipine; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome; United States; Verapamil | 1999 |
Pranidipine enhances the action of nitric oxide released from endothelial cells.
Topics: Amlodipine; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cells, Cultured; Coculture Techniques; Cyclic GMP; Dihydropyridines; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Male; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Superoxide Dismutase | 2000 |
Incidence of gingival hyperplasia caused by calcium antagonists in continuous ambulatory peritoneal dialysis patients.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Cardiovascular Diseases; Felodipine; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Peritoneal Dialysis, Continuous Ambulatory | 1999 |
The calcium channel blocker used with cyclosporin has an effect on gingival overgrowth.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Cyclosporine; Drug Therapy, Combination; Female; Gingival Overgrowth; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Multivariate Analysis; Nifedipine; Prevalence; Prognosis | 2000 |
Calcium antagonists and vascular smooth muscle cell reactivity.
Topics: Amlodipine; Animals; Calcium; Calcium Channel Blockers; Cell Division; Cells, Cultured; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Inbred WKY; Structure-Activity Relationship | 2000 |
Differential effects of calcium channel antagonists in the amelioration of radial artery vasospasm.
Topics: Amlodipine; Calcium Channel Blockers; Coronary Artery Bypass; Diltiazem; Female; Humans; Male; Middle Aged; Nifedipine; Radial Artery; Vasoconstriction | 2000 |
Retrospective evaluation of the conversion of amlodipine to alternative calcium channel blockers.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Felodipine; Female; Humans; Hypertension; Male; Nifedipine; Retrospective Studies | 2000 |
ACE inhibitors attenuate expression of renal transforming growth factor-beta1 in humans.
Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Female; Gene Expression Regulation; Glomerulonephritis; Glomerulonephritis, IGA; Humans; Kidney; Male; Middle Aged; Nifedipine; Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2000 |
Using administrative data to compare the relative effectiveness of amlodipine vs nifedipine CC.
Topics: Adult; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Female; Health Maintenance Organizations; Humans; Insurance Claim Review; Male; Middle Aged; Nifedipine; Patient Compliance; Pennsylvania; Retrospective Studies; Treatment Outcome | 1999 |
Amlodipine increases nitric oxide synthesis in cytokine-stimulated cultured vascualar smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Aorta, Thoracic; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diltiazem; Gene Expression Regulation, Enzymologic; Interleukin-1; Muscle, Smooth, Vascular; NF-kappa B; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2000 |
Nifedipine inhibits activation of transcription factor NF-kappaB.
Topics: Amlodipine; Calcium Channel Blockers; Cell Migration Inhibition; Diltiazem; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Interleukin-1; Lipopolysaccharides; Luciferases; Lung Neoplasms; Lymphocyte Activation; Macrophages; NF-kappa B; Nifedipine; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Verapamil | 2000 |
Effect of nilvadipine in weak acidic medium by 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay.
Topics: Amlodipine; Anticholesteremic Agents; Antioxidants; Bepridil; beta Carotene; Biphenyl Compounds; Buffers; Calcium Channel Blockers; Free Radicals; Hydrogen-Ion Concentration; Nifedipine; Picrates; Probucol | 2001 |
Comparison of amlodipine or nifedipine treatment with developing congestive heart failure: effects on myocyte contractility.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Disease Models, Animal; Heart Failure; Male; Microscopy, Video; Myocardial Contraction; Nifedipine; Pacemaker, Artificial; Swine; Ultrasonography; Ventricular Function, Left | 2001 |
Effect of calcium channel blockers on proteoglycan synthesis by vascular smooth muscle cells and low density lipoprotein--proteoglycan interaction.
Topics: Amlodipine; Calcium Channel Blockers; Cell Count; Cell Survival; Cells, Cultured; Chromatography, Affinity; Humans; Lipoproteins, LDL; Muscle, Smooth, Vascular; Nifedipine; Proteoglycans | 2001 |
Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Calcium Channel Blockers; Costs and Cost Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Treatment Outcome | 2001 |
Pharmacist-managed hypertension therapy conversion.
Topics: Amlodipine; Analysis of Variance; Antihypertensive Agents; Calcium Channel Blockers; Drug Costs; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pharmacists | 2001 |
Preferential renal and mesenteric vasodilation induced by barnidipine and amlodipine in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Hemodynamics; Male; Nifedipine; Rats; Rats, Inbred SHR; Renal Circulation; Splanchnic Circulation; Stereoisomerism; Vasodilation | 2001 |
Deleterious effects of nifedipine on smooth muscle cells implies alterations of intracellular calcium signaling.
Topics: Amlodipine; Aorta; Caffeine; Calcium; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Cells, Cultured; Endoplasmic Reticulum; Enzyme Inhibitors; Felodipine; Genistein; Humans; Muscle, Smooth, Vascular; Nifedipine; Protein-Tyrosine Kinases; Thapsigargin | 2001 |
Effects of calcium antagonists on the nitrergic nerve function in canine corpus cavernosum.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Dogs; Electric Stimulation; In Vitro Techniques; Male; Muscle Relaxation; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; omega-Conotoxin GVIA; Penis | 2001 |
Novel mechanisms of the antiproliferative effects of amlodipine in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cell Division; Cells, Cultured; Growth Substances; Hypertension; Muscle, Smooth, Vascular; Nifedipine; Phenotype; Rats; Rats, Inbred SHR; RNA, Messenger | 2002 |
Preventing radial artery spasm.
Topics: Amlodipine; Arteries; Coronary Vasospasm; Diltiazem; Humans; Nifedipine; Organ Culture Techniques; Radial Artery | 2002 |
Amlodipine, but not verapamil or nifedipine, dilates rabbit femoral artery largely through a nitric oxide- and kinin-dependent mechanism.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cells, Cultured; Endothelium, Vascular; Femoral Artery; Humans; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Rabbits; Receptor, Bradykinin B2; Receptors, Bradykinin; Vasodilation; Verapamil | 2002 |
In vivo receptor binding of benidipine and amlodipine in mesenteric arteries and other tissues of spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Area Under Curve; Blood Proteins; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebral Cortex; Dihydropyridines; Drug Interactions; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocardium; Nifedipine; Protein Binding; Rats; Rats, Inbred SHR; Tissue Distribution | 2002 |
Dihydropyridines are not substitutable without careful monitoring.
Topics: Adverse Drug Reaction Reporting Systems; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Felodipine; Humans; Nifedipine | 2002 |
Antiplatelet activity of semotiadil fumarate.
Topics: Adenosine Diphosphate; Adult; Amlodipine; Calcium Channel Blockers; Case-Control Studies; Collagen; Diltiazem; Humans; Hypertension; Middle Aged; Nifedipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiazoles | 2002 |
The effects of vasodilators on the relaxation of guinea-pig aorta during acute recoil.
Topics: Adrenergic alpha-Antagonists; Amlodipine; Angioplasty, Balloon, Coronary; Animals; Aorta, Thoracic; Disease Models, Animal; Female; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Isosorbide Dinitrate; Muscle Relaxation; Muscle, Smooth, Vascular; Nicorandil; Nifedipine; Phentolamine; Platelet Aggregation Inhibitors; Postoperative Complications; Succinates; Vasodilator Agents | 2002 |
[Pharmaceutical chemistry of "dipines"].
Topics: Amlodipine; Calcium Channel Blockers; Dihydropyridines; Molecular Structure; Nifedipine; Nimodipine; Structure-Activity Relationship | 2002 |
Antioxidant activity of different dihydropyridines.
Topics: Amlodipine; Animals; Antioxidants; Cattle; Cells, Cultured; Dihydropyridines; Endothelium, Vascular; Fluoresceins; Humans; Lipoproteins, LDL; Molecular Structure; Nifedipine; Nimodipine; Reactive Oxygen Species | 2003 |
Life-style and medication compliance in elderly patients.
Topics: Adult; Age Factors; Aged; Amlodipine; Antihypertensive Agents; Drug Administration Schedule; Humans; Hypertension; Life Style; Middle Aged; Nifedipine; Patient Compliance | 1998 |
Effects of long-acting calcium channel antagonists on neurohumoral factors: comparison of nifedipine coat-core with amlodipine.
Topics: Aged; Aged, 80 and over; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Chemistry, Pharmaceutical; Chi-Square Distribution; Delayed-Action Preparations; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Neurotransmitter Agents; Nifedipine; Norepinephrine; Renin | 2003 |
[Heart rate variability in patients with hypertension and type 2 diabetes treated with long acting calcium antagonists].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Verapamil | 2003 |
Protective effect of benidipine against sodium azide-induced cell death in cultured neonatal rat cardiac myocytes.
Topics: Adenosine Triphosphate; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Cell Death; Cells, Cultured; Cysteine Proteinase Inhibitors; Dihydropyridines; Dipeptides; Dose-Response Relationship, Drug; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria, Muscle; Myocytes, Cardiac; Nifedipine; Rats; Rats, Sprague-Dawley; Sodium Azide; Tetrazoles | 2003 |
Risk factors of gingival overgrowth in kidney transplant recipients treated with cyclosporine A.
Topics: Adult; Alleles; Amlodipine; Calcium Channel Blockers; Cyclosporine; Female; Gingival Overgrowth; HLA-DR2 Antigen; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nifedipine; Risk Factors; Sex Factors | 2003 |
Different effects of calcium channel blockers on matrix metalloproteinase-2 expression in cultured rat cardiac fibroblasts.
Topics: Amlodipine; Animals; Animals, Newborn; Benzoquinones; Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibroblasts; Genistein; Lactams, Macrocyclic; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Myocardium; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitroprusside; Protein Kinase Inhibitors; Quinones; Rats; Rats, Wistar; Rifabutin; Verapamil | 2004 |
Effect of nifedipine and amlodipine on wound healing in rats.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Dexamethasone; Female; Glucocorticoids; Male; Nifedipine; Rats; Rats, Wistar; Skin Physiological Phenomena; Tensile Strength; Wound Healing | 2004 |
Effect of nifedipine and amlodipine on dead space wound healing in rats.
Topics: Amlodipine; Animals; Antioxidants; Calcium Channel Blockers; Glycosaminoglycans; Hexosamines; Hexuronic Acids; Hydroxyproline; Male; Nifedipine; Protein-Lysine 6-Oxidase; Rats; Rats, Wistar; Steroids; Superoxide Dismutase; Tensile Strength; Vasodilator Agents; Wound Healing | 2005 |
[Effects of nifedipine controlled release on blood pressure and heart rate of spontaneously hypertensive rats. Comparison with nifedipine standard and with amlodipine].
Topics: Administration, Oral; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Disease Models, Animal; Heart Rate; Male; Nifedipine; Rats; Rats, Inbred SHR; Time Factors; Vasodilator Agents | 2005 |
Increased vascular selectivity and prolonged pharmacological efficacy of the L-type Ca2+ channel antagonist lercanidipine in human cardiovascular tissue.
Topics: Adolescent; Adult; Aged; Amlodipine; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Female; Humans; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Myocardial Contraction; Nifedipine; Protein Binding; Stimulation, Chemical; Vasodilation | 2005 |
Calcium antagonists for secondary prevention of myocardial infarction: is there a need to shift from short-acting to long-acting types?
Topics: Amlodipine; Calcium; Calcium Channel Blockers; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nifedipine; Retrospective Studies | 2005 |
Kinetics and mechanisms of cholesterol esterase inhibition by cardiovascular drugs in vitro.
Topics: Amlodipine; Cardiovascular Agents; Enzyme Inhibitors; Hydralazine; Kinetics; Nifedipine; Octoxynol; Simvastatin; Sterol Esterase; Taurocholic Acid | 2006 |
Effects of benidipine in a rat model for experimental angina.
Topics: Amlodipine; Angina Pectoris; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Male; Nifedipine; Nitrophenols; Organophosphorus Compounds; Rats; Rats, Inbred Strains | 2006 |
Differential effects of dihydropyridine calcium antagonists on doxorubicin-induced nephrotoxicity in rats.
Topics: Amlodipine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Calcium Channel Blockers; Creatinine; Doxorubicin; Glutathione; Glutathione Transferase; Kidney; Kidney Diseases; Male; Malondialdehyde; Nifedipine; Nitrendipine; Nitric Oxide; Nitric Oxide Synthase; Proteinuria; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2007 |
Effects of mebudipine and dibudipine, two new calcium channel blockers on voltage-activated calcium currents of PC12 cells.
Topics: Amlodipine; Animals; Barium Compounds; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Differentiation; Chlorides; Dose-Response Relationship, Drug; Membrane Potentials; Nerve Growth Factor; Neurons; Nifedipine; PC12 Cells; Rats | 2007 |
Effects of benidipine and some other calcium channel blockers on the prognosis of patients with vasospastic angina. Cohort study with evaluation of the ergonovine coronary spasm induction test.
Topics: Adult; Aged; Aging; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cohort Studies; Coronary Angiography; Coronary Stenosis; Coronary Vasospasm; Diabetes Complications; Dihydropyridines; Diltiazem; Ergonovine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifedipine; Oxytocics; Prognosis; Risk Factors | 2007 |
Photochemical stabilities of some dihydropyridine calcium-channel blockers in powdered pharmaceutical tablets.
Topics: Amlodipine; Calcium Channel Blockers; Drug Stability; Nifedipine; Photochemistry; Powders; Tablets | 2008 |
Dihydropyridine calcium channel blockers and cardiovascular outcomes in elderly patients: a population-based study.
Topics: Acute Coronary Syndrome; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Canada; Cohort Studies; Delayed-Action Preparations; Female; Health Surveys; Hospitalization; Humans; Male; Myocardial Infarction; Nifedipine; Proportional Hazards Models; Retrospective Studies | 2008 |
Cost-effectiveness analysis: controlled-release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-Combi) study.
Topics: Amlodipine; Cost-Benefit Analysis; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Japan; Nifedipine; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2008 |
Prevention of vascular injury by combination of an AT1 receptor blocker, olmesartan, with various calcium antagonists.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Chemokine CCL2; Dihydropyridines; Drug Synergism; Femoral Artery; Imidazoles; Ligation; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Neuropeptides; Nifedipine; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Superoxides; Tetrazoles; Tumor Necrosis Factor-alpha; Tunica Intima | 2009 |
Purpura and bleeding due to calcium-channel blockers: an underestimated problem? Case reports and a pilot study.
Topics: Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Female; Hemorrhage; Humans; Male; Middle Aged; Nifedipine; Pilot Projects; Purpura | 2009 |
Effect of the multitargeted receptor tyrosine kinase inhibitor, ABT-869 [N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea], on blood pressure in conscious rats and mice: reversal with antihypertensive agents and effect on tumor growt
Topics: Acrylates; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enalapril; Humans; Imidazoles; Indazoles; Lisinopril; Male; Mice; Mice, SCID; Neoplasms; Nifedipine; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Ramipril; Rats; Rats, Sprague-Dawley; Telmisartan; Thiophenes; Xenograft Model Antitumor Assays | 2009 |
Differential roles of dihydropyridine calcium antagonist nifedipine, nitrendipine and amlodipine on gentamicin-induced renal tubular toxicity in rats.
Topics: Acetylglucosaminidase; Amlodipine; Animals; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Calcium Channel Blockers; Creatine; Gene Expression Regulation; Gentamicins; Glutathione; Glutathione Transferase; Kidney Tubules; Male; Malondialdehyde; Nifedipine; Nitrendipine; Nitric Oxide; Nitric Oxide Synthase; Proteinuria; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2009 |
Calcium channel blockers differentially modulate cytokine production by peripheral blood mononuclear cells.
Topics: Amlodipine; Calcium Channel Blockers; Cytokines; Diltiazem; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1alpha; Interleukin-1beta; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Nifedipine; Tumor Necrosis Factor-alpha; Verapamil | 2010 |
Effects of combination therapy with angiotensin II type I receptor blockers and calcium channel blockers on renal function in hypertensive patients/a retrospective, "real-world" comparative study.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Creatinine; Dihydropyridines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hypertension; Kaplan-Meier Estimate; Kidney; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Nifedipine; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Treatment Outcome | 2010 |
Effects of ingestion of grapefruit juice or grapefruit on the hypotensive effect and plasma concentrations of dihydropyridine calcium antagonists (amlodipine and nifedipine): a case study.
Topics: Amlodipine; Beverages; Blood Pressure; Calcium Channel Blockers; Citrus paradisi; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Food-Drug Interactions; Humans; Hypertension; Japan; Male; Middle Aged; Nifedipine | 2010 |
[Antihypertrophic effect of dihydropyridines calcium channel blockers is dependent on their potential of blocking N-type calcium channel].
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cardiomegaly; Dihydropyridines; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Nifedipine | 2010 |
Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice.
Topics: Amlodipine; Animals; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Cardiovascular Agents; Cells, Cultured; Chelating Agents; Chemokine CCL2; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Flavonoids; Humans; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Nifedipine; Phosphorylation; PPAR gamma; Protein Kinase Inhibitors; RNA Interference; RNA, Messenger; Time Factors; Transfection | 2010 |
Effect of the two new calcium channel blockers mebudipine and dibudipine in comparison to amlodipine on vascular flow of isolated kidney of diabetic rat.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney; Male; Nifedipine; Rats; Rats, Wistar; Renal Circulation | 2010 |
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Flunarizine; Humans; Intracellular Space; Membrane Glycoproteins; Molecular Chaperones; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Nicardipine; Nifedipine; Nimodipine; Potassium Chloride; RNA Interference; RNA, Small Interfering | 2011 |
Microarray and quantitative RT-PCR analyses in calcium-channel blockers induced gingival overgrowth tissues of periodontitis patients.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Case-Control Studies; Cathepsin L; Cluster Analysis; Female; Gene Expression Profiling; Gingival Overgrowth; Humans; Keratin-10; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 12; Middle Aged; Nifedipine; Oligonucleotide Array Sequence Analysis; Periodontitis; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2011 |
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Topics: Amlodipine; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Body Weight; Calcium Channel Blockers; Dihydropyridines; Down-Regulation; Gelatinases; Hypertension, Renovascular; Hypertrophy; Lipid Peroxides; Male; Matrix Metalloproteinase 2; Nifedipine; Nimodipine; Rats; Rats, Wistar; Reactive Oxygen Species; Tunica Media | 2011 |
Comparison of daily anti-hypertensive effects of amlodipine and nifedipine coat-core using ambulatory blood pressure monitoring - utility of "hypobaric curve" and "hypobaric area".
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chronobiology Phenomena; Circadian Rhythm; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors; Treatment Outcome | 2011 |
Assessment on antihypertensive effect and safety of nifedipine controlled-release tablet administered at 80 mg/day in practical clinic.
Topics: Adult; Age Factors; Aged; Ambulatory Care Facilities; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Diabetes Complications; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Renal Insufficiency, Chronic; Time Factors; Treatment Failure | 2012 |
Amlodipine in pediatric patient with uncontrolled multifactorial hypertension. Formulation of amlodipine oral suspension.
Topics: Administration, Oral; Amlodipine; Calcium Channel Blockers; Child, Preschool; Female; Humans; Hypertension; Nifedipine; Suspensions | 2012 |
Neuroprotective effects of amlodipine besylate and benidipine hydrochloride on oxidative stress-injured neural stem cells.
Topics: Amlodipine; Animals; Apoptosis; Calcium Channel Blockers; Cell Proliferation; Cell Survival; Cells, Cultured; Mitogen-Activated Protein Kinase 3; Neural Stem Cells; Neuroprotective Agents; Nifedipine; Oxidative Stress; Phosphatidylinositol 3-Kinase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Desirability function approach for the optimization of an in-syringe ultrasound-assisted emulsification-microextraction method for the simultaneous determination of amlodipine and nifedipine in plasma samples.
Topics: Amlodipine; Humans; Limit of Detection; Liquid Phase Microextraction; Nifedipine; Ultrasonics | 2014 |
Effect of calcium channel blockers on paraoxonase-1 (PON1) activity and oxidative stress.
Topics: Amlodipine; Aryldialkylphosphatase; Calcium Channel Blockers; Humans; Isradipine; Nifedipine; Nitrendipine; Oxidative Stress | 2014 |
Role of transforming growth factor β-connective tissue growth factor pathway in dihydropyridine calcium channel blockers-induced gingival overgrowth.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Calcium Channels, L-Type; Connective Tissue Growth Factor; Female; Gingiva; Gingival Overgrowth; Humans; Immunohistochemistry; Male; Nifedipine; Signal Transduction; Transforming Growth Factor beta | 2014 |
Extended-release nifedipine and the risk of intestinal obstruction: a population-based study.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Cohort Studies; Delayed-Action Preparations; Female; Humans; Intestinal Obstruction; Male; Nifedipine; Retrospective Studies; Risk Assessment | 2014 |
Prediction of drug interaction between oral adsorbent AST-120 and concomitant drugs based on the in vitro dissolution and in vivo absorption behavior of the drugs.
Topics: Administration, Oral; Adsorption; Aluminum Hydroxide; Amlodipine; Aspirin; Carbon; Drug Interactions; Glycine; Humans; Intestinal Absorption; Losartan; Magnesium; Metoprolol; Models, Biological; Nifedipine; Oxides; Renal Insufficiency, Chronic; Solubility; Triazolam | 2016 |
Replacement of Amlodipine and Lercanidipine by Barnidipine: Tolerability and Effectiveness in a Real-Life Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Substitution; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Product Surveillance, Postmarketing; Prospective Studies; Time Factors; Treatment Outcome | 2017 |
Influence of 3 calcium channel blockers on gingival overgrowth in a population of severe refractory hypertensive patients.
Topics: Adult; Aged; Amlodipine; Brazil; Calcium Channel Blockers; Felodipine; Female; Gingival Overgrowth; Humans; Hypertension; Male; Middle Aged; Nifedipine; Periodontal Index | 2018 |
L-type calcium channel blockers and a symptom complex mimicking de Melo-Souza's syndrome.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Calcium Channels, L-Type; Diagnosis, Differential; Female; Humans; Inappropriate ADH Syndrome; Nifedipine; Parkinson Disease, Secondary; Tremor | 2019 |
Low-dose combination therapy to control sustained ambulatory hypertension-Basic principles and future directions.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Nifedipine; Valsartan; Vascular Stiffness | 2019 |
Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Topics: Amlodipine; Calcium Channel Blockers; Cell Differentiation; Cells, Cultured; Diltiazem; Humans; Induced Pluripotent Stem Cells; Myocytes, Cardiac; Myosin Heavy Chains; Nifedipine; Transcriptome; Verapamil | 2019 |
Differential effects on out-of-hospital cardiac arrest of dihydropyridines: real-world data from population-based cohorts across two European countries.
Topics: Action Potentials; Aged; Amlodipine; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Denmark; Dose-Response Relationship, Drug; Female; Humans; Induced Pluripotent Stem Cells; Male; Middle Aged; Myocytes, Cardiac; Netherlands; Nifedipine; Out-of-Hospital Cardiac Arrest; Registries; Retrospective Studies; Risk Assessment; Risk Factors | 2020 |
Calcium channel blockers, survival and ischaemic stroke in patients with dementia: a Swedish registry study.
Topics: Alzheimer Disease; Amlodipine; Brain Ischemia; Calcium Channel Blockers; Humans; Hypertension; Ischemic Stroke; Longitudinal Studies; Nifedipine; Registries; Sweden | 2021 |
Treatment of calcium channel blocker-induced gingival overgrowth without modifying medication.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Gingival Overgrowth; Humans; Hypertension; Male; Nifedipine | 2021 |
Combination of aqueous extracts of Curcuma longa (turmeric) and some calcium channel blockers synergistically improves CCl4-induced nephrotoxicity in albino rats.
Topics: Acute Kidney Injury; Amlodipine; Animals; Antioxidants; Calcium Channel Blockers; Carbon Tetrachloride; Curcuma; Disease Models, Animal; Drug Synergism; Kidney; Male; Mice; Nifedipine; Oxidative Stress; Plant Extracts; Rats, Wistar | 2020 |
Amlodipine Induced Gum Hypertrophy: A Rare Case Report.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Gingival Hyperplasia; Gingival Overgrowth; Humans; Hyperplasia; Hypertrophy; Nifedipine | 2022 |
Comparative efficacy of generic nifedipine versus brand-name amlodipine for hypertension management in Taiwan.
Topics: Amlodipine; Calcium Channel Blockers; Drugs, Generic; Heart Failure; Humans; Hypertension; Ischemic Stroke; Myocardial Infarction; Nifedipine; Taiwan | 2022 |
Antihypertensive drug prescription trends for pregnant women with hypertension in acute hospitals in Japan.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Drug Prescriptions; Female; Hospitals; Humans; Hypertension; Japan; Methyldopa; Nifedipine; Pregnancy; Pregnant Women | 2022 |
Antihypertensive medicine use differs between Ghana and Nigeria.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Ghana; Humans; Hypertension; Lisinopril; Losartan; Nifedipine; Nigeria | 2022 |
Delayed Decline of Cognitive Function by Antihypertensive Agents: A Cohort Study Linked with Genotype Data.
Topics: Adrenergic Antagonists; Adult; Aged; Amlodipine; Antihypertensive Agents; Apolipoprotein E4; Calcium Channel Blockers; Cognition; Cohort Studies; Dihydropyridines; Diuretics; Diuretics, Potassium Sparing; Genotype; Humans; Hypertension; Nifedipine; Thiazides; Vasodilator Agents | 2022 |
Fundamental Investigation of Adsorption Behavior onto Sodium Polystyrene Sulfonate to Potassium Ions and Its Concomitant Drugs in the Digestive Tract.
Topics: Adsorption; Amlodipine; Gastrointestinal Tract; Ions; Nifedipine; Potassium | 2022 |
Effects of 5-fluorouracil Co-administration on Blood Pressure in Patients Maintained on Antihypertensives: a Retrospective Case Series.
Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Fluorouracil; Humans; Hypertension; Nifedipine; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2023 |
NITROSAMINE CONTAMINATION WITHIN CARDIAC MULTIMEDICATION - SARTANS (VALSARTAN), CALCIUM CHANNEL BLOCKERS (AMLODIPINE AND NIFEDIPINE), AND ANTIARRHYTHMICS (PROPAFENONE) AS A SIGNIFICANT FACTOR IN THE DEVELOPMENT AND PROGRESSION OF MULTIPLE KERATINOCYTIC CA
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Calcium Channel Blockers; Carcinogens; Humans; Keratoacanthoma; Neoplasms; Nifedipine; Nitrosamines; Propafenone; Shoulder; Surgical Flaps; Valsartan | 2023 |