amlodipine has been researched along with metoprolol in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (8.11) | 18.2507 |
| 2000's | 24 (32.43) | 29.6817 |
| 2010's | 33 (44.59) | 24.3611 |
| 2020's | 11 (14.86) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Beaumont, K; Di, L; Maurer, TS; Smith, DA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Julínek, J; Meluzín, J; Novák, M; Simek, P; Spinarová, L; Stejfa, M; Toman, J; Zeman, K | 1 |
| Bucca, C; Cacciafesta, M; Di Gioacchino, C; Durante, M; Fimognari, FL; Lo Verde, A; Marigliano, V; Monteforte, G; Munizzi, MR; Piccirillo, G; Santagada, E; Tarantini, S; Viola, E | 1 |
| Barrow, SE; Benjamin, N; Brett, SE; Ritter, JM; Stratton, PD; Woods, JD | 1 |
| Danielson, BG; Hägg, A; Linde, T; Mörlin, C; Sandhagen, B | 1 |
| Boivin, JM; Zannad, F | 1 |
| Buchholz-Varley, C; Freudenberger, RS; Kalman, J; Kukin, ML; Mannino, MM; Ocampo, ON; Steinmetz, M | 1 |
| Fukuzawa, M; Miyaguchi, S; Nakazawa, T; Ohta, S; Qiang, X; Sakata, Y; Satoh, J; Takahashi, K; Takizawa, Y; Toyota, T | 1 |
| Midtbø, K; Mølstad, P | 1 |
| Agodoa, LY; Appel, L; Bakris, GL; Beck, G; Bourgoignie, J; Briggs, JP; Charleston, J; Cheek, D; Cleveland, W; Douglas, JG; Douglas, M; Dowie, D; Faulkner, M; Gabriel, A; Gassman, J; Greene, T; Hall, Y; Hebert, L; Hiremath, L; Jamerson, K; Johnson, CJ; Kopple, J; Kusek, J; Lash, J; Lea, J; Lewis, JB; Lipkowitz, M; Massry, S; Middleton, J; Miller, ER; Norris, K; O'Connor, D; Ojo, A; Phillips, RA; Pogue, V; Rahman, M; Randall, OS; Rostand, S; Schulman, G; Smith, W; Thornley-Brown, D; Tisher, CC; Toto, RD; Wright, JT; Xu, S | 1 |
| McConaghy, JR | 1 |
| Agodoa, LY; Appel, LJ; Bakris, G; Charleston, J; Cheek, D; Douglas-Baltimore, JG; Gassman, J; Glassock, R; Greene, T; Hebert, L; Jamerson, K; Lewis, J; Middleton, JP; Phillips, RA; Rostand, SG; Toto, RD; Wright, JT | 1 |
| Gedgafova, SIu; Martynov, AI; Ostroumova, OD; Pustovitova, TS; Sharkova, NE; Sinitsyn, VE; Ternovoĭ, SK | 1 |
| Agodoa, L; Douglas, JG | 1 |
| Agodoa, LY; Cheek, D; Contreras, G; Dowie, D; Greene, T; Junco, G; Lash, J; Lipkowitz, M; Miller, ER; Ojo, A; Sika, M; Toto, RD; Wilkening, B | 1 |
| Agodoa, LY; Appel, LJ; Cheek, D; Contreras, G; Gassman, J; Lash, JP; Miller, ER; Randall, OS; Thornley-Brown, D; Wang, X; Wright, JT | 1 |
| Gadegbeku, CA; Greene, T; Hall, Y; Jones, K; Kusek, JW; Lash, JP; Sika, M; Unruh, M; Wang, X | 1 |
| Toto, RD | 1 |
| Albini, TA; Foroozan, R; Lakhanpal, RR; Lopez, GA; McPherson, AR | 1 |
| Acikel, C; Caglar, K; Celik, T; Eyileten, T; Oguz, Y; Sonmez, A; Vural, A; Yavuz, I; Yenicesu, M; Yilmaz, MI | 1 |
| Adamczak, M; Chudek, J; Piecha, G; Wiecek, A | 1 |
| Dongre, VG; Jadhav, VK; Karmuse, PP; Phadke, M; Shah, SB | 1 |
| Yee, J | 1 |
| Gutkowski, W; Janion, M; Sielski, J; Stepień, A | 1 |
| Barnett, PG; Boden, WE; Bowen, J; Deaton, C; Dunbar, SB; Goeree, R; Hartigan, PM; Jurkovitz, C; Kaufman, S; Kolm, P; Lewis, C; Mancini, GB; Maron, DJ; O'Rourke, RA; Spertus, JA; Teo, KK; Veledar, E; Weintraub, WS; Zhang, W; Zhang, Z | 1 |
| Agarwal, S; Bhaumik, U; Bose, A; Das, A; Ghosh, D; Gowda, KV; Mandal, U; Pal, TK; Sarkar, AK; Selvan, PS | 1 |
| Chandurkar, NB; Gupta, BS; Pareek, A; Sharma, R; Tiwari, D | 1 |
| Bolen, MA; Halliburton, SS; Schoenhagen, P | 1 |
| Appel, LJ; Astor, BC; Davis, EM; Greene, T; Lipkowitz, MS; Pogue, VA; Rahman, M; Toto, R; Wang, X; Wright, JT | 1 |
| Chobanian, AV | 1 |
| Bosco, B; Devi, P; Ds, C; Gupta, R; Hiremath, J; Joshi, S; Mehta, K; Murthy, S; Nambiar, A; Pais, P; Pandey, S; Sharma, K; Sigamani, A; Singh, G; Thomas, T; Xavier, D | 1 |
| Alanichev, AE; Makiev, RG; Sukhov, VIu; Svistov, AS | 1 |
| Nolan, KA; Oshman, RG; Phelps, RG; Pulitzer, MP | 1 |
| Hu, WL; Ji, M; Li, SJ | 1 |
| Alanichev, AE; Fisun, AIa; Makiev, RG; Ovchinnikov, IuV; Rakhimova, OIu; Shachnovich, PG | 1 |
| Dmuchowska, DA; Jasiewicz, M; Krasnicki, P; Mariak, Z; Mikita, A; Sarraf, D; Sobkowicz, B; Zalewska, R | 1 |
| Anthony, EG; Bhatnagar, V; Lipkowitz, MS; Richard, E | 1 |
| Bain, J; Ferguson, NM; Maskell, KF; Wills, BK | 1 |
| Gründer, G; Haen, E; Lammertz, SE; Paulzen, M; Schoretsanitis, G; Schruers, KR; Stegmann, B; Walther, S | 1 |
| Kotegawa, T; Koya, Y; Machi, Y; Namiki, N; Shobu, Y; Uchida, S | 1 |
| Chen, J; Jing, YH; Li, BQ; Wang, X; Xu, ML; Zhai, HL | 1 |
| El-Malla, SF; Elshenawy, EA; Hammad, SF; Mabrouk, MM | 1 |
| Ayyagari, R; Chen, S; Cheng, D; Huang, XY; Wu, EQ; Xie, J | 1 |
| Deng, X; He, M; Li, Y; Liu, G; Pan, Y; Shi, J; Sun, D; Wang, J; Wang, W; Yuan, Y | 1 |
| Buus, NH; Christensen, KL; Ivarsen, P; Jespersen, B; Khatir, DS; Pedersen, M | 1 |
| Ahlner, J; Forsman, P; Kugelberg, FC; Lindeman, E; Nordmark Grass, J; Steinwall, J | 1 |
| Appel, LJ; Juraschek, SP; Lipsitz, LA; Miller, ER; Mukamal, KJ | 1 |
| Blaich, C; Hoffmann, F; Johannsen, JO; Müller, C; Reuter, H; Streichert, T; Wiesen, MHJ | 1 |
| Du, Y; Feng, Z; Huang, Z; Sun, X; Zhao, S | 1 |
| Bachmann, HS; Besser, M; Severing, AL; Stuermer, EK; Terberger, N | 1 |
| Chen, C; Ding, W; Du, Y; Ma, X; Sun, X; Tao, Y | 1 |
| Alves Saldanha, S; Buclin, T; Cavassini, M; Courlet, P; Csajka, C; Decosterd, LA; Desfontaine, V; Marzolini, C; Spaggiari, D | 1 |
| Ghafarzadeh, M; Namdari, P; Shakarami, A; Yari, F | 1 |
| Bangh, SA; Cole, JB; Corcoran, JN; Jacoby, KJ; Olives, TD | 1 |
| Glick, A; Johnson, C; Sista, V | 1 |
| Hammad, SF; Kamal, AH; Kamel, DN | 1 |
| Lauder, L; Mahfoud, F; Meyer, MR; Vollmer, AC; Wagmann, L | 1 |
| Agrawal, S; Anand, J; Bachani, D; Doshi, M; Gaikwad, VB; Halder, SK; Kinholkar, B; Kumar, DA; Kumbhar, A; Mathur, R; Mehta, S; Sarkar, G; Sharma, A | 1 |
| Du, Y; Kan, Z; Ma, M; Zhang, J; Zhang, X | 1 |
| Biswas, A; Chen, X; Ghazi, L; Hanna, J; Li, F; Peixoto, AJ; Shah, T; Simonov, M; Wilson, FP; Yamamoto, Y | 1 |
| Ballotari, M; Gottardo, R; Tagliaro, F; Taus, F; Utzeri, C | 1 |
| Tchernev, G | 1 |
| Chen, C; Jiao, D; Shen, J; Zhang, W; Zhang, X; Zhu, G | 1 |
2 review(s) available for amlodipine and metoprolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Lessons from the African-American Study of Kidney Disease and Hypertension: an update.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Hypertension; Kidney Failure, Chronic; Metoprolol; Nephrosclerosis; Ramipril; Randomized Controlled Trials as Topic; Treatment Outcome | 2006 |
25 trial(s) available for amlodipine and metoprolol
| Article | Year |
|---|---|
Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle.
Topics: Amlodipine; Angina Pectoris; Diastole; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Metipranolol; Metoprolol; Myocardial Infarction; Nitroglycerin; Systole; Ventricular Function, Left | 1992 |
Power spectral analysis of heart rate in elderly hypertensive subjects with or without silent coronary disease.
Topics: Aged; Algorithms; Amlodipine; Antihypertensive Agents; Case-Control Studies; Coronary Disease; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Hypertension; Isoquinolines; Male; Metoprolol; Quinapril; Signal Processing, Computer-Assisted; Sympathetic Nervous System; Tetrahydroisoquinolines | 1996 |
Prostacyclin biosynthesis in essential hypertension before and during treatment.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Amlodipine; Antihypertensive Agents; Bendroflumethiazide; Epoprostenol; Female; Humans; Hypertension; Isoquinolines; Male; Metoprolol; Middle Aged; Quinapril; Tetrahydroisoquinolines; Thromboxane A2; Thromboxane B2 | 1996 |
Decreased blood viscosity and serum levels of erythropoietin after anti-hypertensive treatment with amlodipine or metoprolol: results of a cross-over study.
Topics: Adult; Aged; Amlodipine; Blood Cell Count; Blood Chemical Analysis; Blood Viscosity; Cross-Over Studies; Erythropoietin; Female; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged | 1996 |
Ambulatory 24-h blood pressure assessment of the felodipine-metoprolol combination versus amlodipine in mild to moderate hypertension. Lorraine General Physician Investigators Group.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged | 1999 |
Short-term and long-term hemodynamic and clinical effects of metoprolol alone and combined with amlodipine in patients with chronic heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Amlodipine; Calcium Channel Blockers; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome; Vascular Resistance | 1999 |
Amlodipine versus slow release metoprolol in the treatment of stable exertional angina pectoris (AMSA).
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Delayed-Action Preparations; Double-Blind Method; Electrocardiography; Exercise Test; Female; Humans; Male; Metoprolol; Middle Aged; Physical Exertion | 2000 |
Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: a randomized controlled trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black or African American; Calcium Channel Blockers; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Failure, Chronic; Male; Metoprolol; Middle Aged; Nephrosclerosis; Proportional Hazards Models; Proteinuria; Ramipril | 2001 |
What is the best treatment for slowing the progression to end-stage renal disease (ESRD) in African Americans with hypertensive nephropathy?
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black People; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Metoprolol; Middle Aged; Ramipril | 2001 |
Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black or African American; Blood Pressure; Calcium Channel Blockers; Disease Progression; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Failure, Chronic; Male; Metoprolol; Middle Aged; Proportional Hazards Models; Proteinuria; Ramipril | 2002 |
ACE inhibition is effective and renoprotective in hypertensive nephrosclerosis: the African American Study of Kidney Disease and Hypertension (AASK) trial.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Black or African American; Calcium Channel Blockers; Glomerular Filtration Rate; Humans; Hypertension, Renal; Metoprolol; Nephrosclerosis; Ramipril; Renal Insufficiency | 2003 |
Blood pressure control, drug therapy, and kidney disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black or African American; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Metoprolol; Middle Aged; Proteinuria; Ramipril; Treatment Outcome | 2005 |
Quality of life in the African American Study of Kidney Disease and Hypertension: effects of blood pressure management.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Female; Humans; Hypertension; Kidney Diseases; Male; Metoprolol; Middle Aged; Nephrosclerosis; Outcome Assessment, Health Care; Quality of Life; Ramipril | 2006 |
Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome.
Topics: Adiponectin; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Doxazosin; Female; Humans; Hypertension; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Metoprolol; Middle Aged; Predictive Value of Tests; Prospective Studies; Ramipril; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2007 |
Indapamide decreases plasma adiponectin concentration in patients with essential hypertension.
Topics: Adiponectin; Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Enalapril; Female; Glomerular Filtration Rate; Homeostasis; Humans; Hypertension, Renal; Indapamide; Insulin Resistance; Lipids; Male; Metoprolol; Middle Aged | 2007 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Calcium Channel Blockers; Clopidogrel; Combined Modality Therapy; Coronary Disease; Cross-Over Studies; Drug Therapy, Combination; Female; Health Status; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Patient Satisfaction; Platelet Aggregation Inhibitors; Quality of Life; Stents; Surveys and Questionnaires; Ticlopidine; Vasodilator Agents | 2008 |
Efficacy and tolerability of a fixed-dose combination of metoprolol extended release/amlodipine in patients with mild-to-moderate hypertension: a randomized, parallel-group, multicentre comparison with losartan plus amlodipine.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Electrolytes; Female; Heart Rate; Humans; Losartan; Male; Metoprolol; Middle Aged; Young Adult | 2010 |
Limitations of analyses based on achieved blood pressure: lessons from the African American study of kidney disease and hypertension trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Male; Metoprolol; Middle Aged; Proportional Hazards Models; Ramipril; Time Factors; Treatment Outcome | 2011 |
Effect of fixed dose combinations of metoprolol and amlodipine in essential hypertension: MARS--a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged | 2011 |
Effects of different antihypertensive drugs on blood pressure variability in patients with ischemic stroke.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Stroke | 2014 |
Association of the ADRB2 (rs2053044) polymorphism and angiotensin-converting enzyme-inhibitor blood pressure response in the African American Study of Kidney Disease and Hypertension.
Topics: 5' Untranslated Regions; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Black or African American; Blood Pressure; Female; Humans; Hypertension; Male; Metoprolol; Ramipril; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2 | 2015 |
Metoprolol has a similar therapeutic effect as amlodipine on BP lowering in hypertensive patients with obstructive sleep apnea.
Topics: Administration, Oral; Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cohort Studies; Comorbidity; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Polysomnography; Prospective Studies; Sleep Apnea, Obstructive | 2019 |
Effects of additional vasodilatory or nonvasodilatory treatment on renal function, vascular resistance and oxygenation in chronic kidney disease: a randomized clinical trial.
Topics: Amlodipine; Angiotensins; Antihypertensive Agents; Disease Progression; Glomerular Filtration Rate; Humans; Kidney Function Tests; Metoprolol; Renal Insufficiency, Chronic; Vascular Resistance; Vasodilator Agents | 2019 |
Hypertension Treatment Effects on Orthostatic Hypotension and Its Relationship With Cardiovascular Disease.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Drug Monitoring; Female; Humans; Hypertension; Hypotension, Orthostatic; Male; Metoprolol; Middle Aged; Outcome Assessment, Health Care; Ramipril; United States | 2018 |
Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Coronary Artery Disease; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metoprolol; Telmisartan; Tetrazoles | 2022 |
47 other study(ies) available for amlodipine and metoprolol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Volume of Distribution in Drug Design.
Topics: Drug Design; Half-Life; Pharmacokinetics | 2015 |
Modulation of tumor necrosis factor-alpha production with anti-hypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Diuretics; Doxazosin; Humans; Hydrochlorothiazide; Interleukin-1; Interleukin-6; Lipopolysaccharides; Male; Metoprolol; Mice; Mice, Inbred BALB C; Monocytes; Nicardipine; Nitrobenzenes; Piperazines; Sodium Chloride Symporter Inhibitors; Tumor Necrosis Factor-alpha | 2000 |
[Changes of distensibility of the aorta in elderly patients during long-term therapy with various classes of hypotensive drugs (magnetic resonance tomography data)].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aorta; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Data Interpretation, Statistical; Diuretics; Elasticity; Female; Fosinopril; Humans; Hypertension; Indapamide; Magnetic Resonance Imaging; Male; Metoprolol; Middle Aged; Models, Biological; Risk Factors; Time Factors | 2002 |
Differing effects of antihypertensive drugs on the incidence of diabetes mellitus among patients with hypertensive kidney disease.
Topics: Adrenergic beta-Antagonists; Adult; Amlodipine; Antihypertensive Agents; Black or African American; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension, Renal; Incidence; Male; Metoprolol; Middle Aged; Multicenter Studies as Topic; Ramipril; Randomized Controlled Trials as Topic; Regression Analysis | 2006 |
Retinopathy and choroidopathy as the initial signs of hypertensive brainstem encephalopathy.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Brain Stem; Choroid Diseases; Drug Therapy, Combination; Female; Fluorescein Angiography; Humans; Hypertensive Encephalopathy; Magnetic Resonance Imaging; Metoprolol; Middle Aged; Retinal Diseases; Tetrazoles; Valine; Valsartan | 2006 |
Simultaneous determination of metoprolol succinate and amlodipine besylate in pharmaceutical dosage form by HPLC.
Topics: Amlodipine; Chromatography, High Pressure Liquid; Metoprolol; Tablets | 2008 |
Chronic kidney disease--a disease domain complex.
Topics: Aged; Alendronate; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Bone Density Conservation Agents; Calcium; Diabetes Mellitus, Type 2; Disease Progression; Drug Therapy; Female; Glomerular Filtration Rate; Humans; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin, Long-Acting; Kidney Failure, Chronic; Metoprolol; Nitroglycerin; Sulfonamides; Thiophenes | 2008 |
Is the intra-aortic balloon pump a method of brain protection during cardiogenic shock after drug intoxication?
Topics: Adolescent; Adrenergic beta-Antagonists; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Brain Diseases; Calcium Channel Blockers; Female; Humans; Ibuprofen; Intra-Aortic Balloon Pumping; Metoprolol; Shock, Cardiogenic; Suicide, Attempted; Verapamil | 2010 |
Simultaneous determination of metoprolol succinate and amlodipine besylate in human plasma by liquid chromatography-tandem mass spectrometry method and its application in bioequivalence study.
Topics: Amlodipine; Chromatography, Liquid; Drug Stability; Metoprolol; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Therapeutic Equivalency; Uncertainty | 2008 |
Iterative CT reconstruction of aortic intramural hematoma.
Topics: Amlodipine; Aortic Aneurysm; Aortic Dissection; Captopril; Drug Therapy, Combination; Female; Hematoma; Humans; Hydralazine; Metoprolol; Middle Aged; Multidetector Computed Tomography; Simvastatin; Treatment Outcome | 2011 |
Mixed messages on blood pressure goals.
Topics: Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Metoprolol; Ramipril; Treatment Outcome | 2011 |
[Use of SPECT-scanning of the heart in estimating of influence of drugs of the background therapy of ischemic heart disease on myocardial perfusion].
Topics: Amlodipine; Antihypertensive Agents; Blood Flow Velocity; Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography; Coronary Angiography; Coronary Circulation; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Metoprolol; Myocardial Ischemia; Myocardial Reperfusion | 2012 |
CD30+ lymphomatoid drug reactions.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amines; Amlodipine; Anti-Bacterial Agents; Anticonvulsants; Biomarkers; Biopsy; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Eruptions; Erythema; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Ki-1 Antigen; Levofloxacin; Lymphocytes; Lymphoproliferative Disorders; Male; Metoprolol; Middle Aged; Ofloxacin; Predictive Value of Tests; Pseudolymphoma; Selective Serotonin Reuptake Inhibitors; Sertraline; Skin | 2013 |
[Evaluation of myocardial perfusion by single-photon emission CT in the treatment with beta-adrenoblockers and calcium channel blockers].
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina, Stable; Calcium Channel Blockers; Coronary Angiography; Coronary Vessels; Drug Monitoring; Female; Heart Function Tests; Humans; Male; Metoprolol; Microcirculation; Middle Aged; Myocardial Perfusion Imaging; Prognosis; Severity of Illness Index; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2014 |
Diagnostic and Therapeutic Challenges.
Topics: Amlodipine; Antihypertensive Agents; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Macular Edema; Metoprolol; Middle Aged; Phosphodiesterase 5 Inhibitors; Retinal Detachment; Sildenafil Citrate; Vision Disorders | 2015 |
Survival After Cardiac Arrest: ECMO Rescue Therapy After Amlodipine and Metoprolol Overdose.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Amlodipine; Calcium Channel Blockers; Drug Overdose; Extracorporeal Membrane Oxygenation; Heart Arrest; Humans; Male; Metoprolol; Suicide, Attempted; Treatment Outcome | 2017 |
Pharmacokinetic considerations in the treatment of hypertension in risperidone-medicated patients - thinking of clinically relevant CYP2D6 interactions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Databases, Factual; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Female; Humans; Hypertension; Male; Mental Disorders; Metoprolol; Middle Aged; Paliperidone Palmitate; Retrospective Studies; Risperidone; Young Adult | 2016 |
Prediction of drug interaction between oral adsorbent AST-120 and concomitant drugs based on the in vitro dissolution and in vivo absorption behavior of the drugs.
Topics: Administration, Oral; Adsorption; Aluminum Hydroxide; Amlodipine; Aspirin; Carbon; Drug Interactions; Glycine; Humans; Intestinal Absorption; Losartan; Magnesium; Metoprolol; Models, Biological; Nifedipine; Oxides; Renal Insufficiency, Chronic; Solubility; Triazolam | 2016 |
Krawtchouk image moment method for the simultaneous determination of three drugs in human plasma based on fluorescence three-dimensional spectra.
Topics: Amlodipine; Humans; Imaging, Three-Dimensional; Limit of Detection; Linear Models; Metoprolol; Models, Theoretical; Niacin; Reproducibility of Results; Spectrometry, Fluorescence | 2016 |
Simultaneous determination of amlodipine and metoprolol in their combined dosage form using a synchronous fluorescence spectrofluorimetric method.
Topics: Amlodipine; Antihypertensive Agents; Metoprolol; Spectrometry, Fluorescence; Tablets | 2018 |
A retrospective study evaluating the tolerability and effectiveness of adjunctive antihypertensive drugs in patients with inadequate response to initial treatment.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nebivolol; Random Allocation; Retrospective Studies; Treatment Outcome | 2018 |
A case of massive metoprolol and amlodipine overdose with blood concentrations and survival following extracorporeal corporeal membrane oxygenation (ECMO).
Topics: Adult; Amlodipine; Drug Overdose; Extracorporeal Membrane Oxygenation; Female; Humans; Metoprolol; Suicide, Attempted; Treatment Outcome | 2019 |
Reliable and easy-to-use LC-MS/MS-method for simultaneous determination of the antihypertensives metoprolol, amlodipine, canrenone and hydrochlorothiazide in patients with therapy-refractory arterial hypertension.
Topics: Amlodipine; Antihypertensive Agents; Canrenone; Carbon Isotopes; Chromatography, High Pressure Liquid; Deuterium; Drug Monitoring; Drug Resistance; Humans; Hydrochlorothiazide; Hypertension; Limit of Detection; Male; Metoprolol; Middle Aged; Reproducibility of Results; Tandem Mass Spectrometry | 2019 |
Enantioseparation of propranolol, amlodipine and metoprolol by electrochromatography using an open tubular capillary modified with β-cyclodextrin and poly(glycidyl methacrylate) nanoparticles.
Topics: Amlodipine; beta-Cyclodextrins; Capillary Electrochromatography; Metoprolol; Nanoparticles; Polymethacrylic Acids; Propranolol; Stereoisomerism | 2019 |
Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitro.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cell Line; Cell Movement; Diuretics; Fibroblasts; Humans; Hydrochlorothiazide; Keratinocytes; Metoprolol; Ramipril; Tetrazoles; Wound Healing | 2019 |
Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs.
Topics: Amlodipine; beta-Cyclodextrins; Capillary Electrochromatography; Metal-Organic Frameworks; Metoprolol; Propanolamines; Propranolol; Sotalol; Stereoisomerism | 2019 |
UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.
Topics: Amlodipine; Anti-HIV Agents; Atorvastatin; Chromatography, High Pressure Liquid; Drug Interactions; HIV Infections; Humans; Linear Models; Metoprolol; Pravastatin; Reproducibility of Results; Rosuvastatin Calcium; Sensitivity and Specificity; Tandem Mass Spectrometry | 2019 |
The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Incidence; Methyldopa; Metoprolol; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications, Cardiovascular; Prevalence; Retrospective Studies; Risk | 2020 |
Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report.
Topics: Adrenergic beta-1 Receptor Antagonists; Amlodipine; Bradycardia; Calcium Channel Blockers; Drug Administration Schedule; Drug Overdose; Humans; Hyperinsulinism; Hypoglycemic Agents; Hypotension; Infusions, Intravenous; Insulin; Male; Metoprolol; Middle Aged; Suicide, Attempted | 2020 |
Oral Manifestations of Commonly Prescribed Drugs.
Topics: Albuterol; Amlodipine; Anticonvulsants; Antihypertensive Agents; Atorvastatin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bronchodilator Agents; Deprescriptions; Drug Hypersensitivity; Fluorides; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperpigmentation; Hypoglycemic Agents; Lisinopril; Losartan; Metformin; Metoprolol; Mouth Diseases; Omeprazole; Oral Hygiene; Proton Pump Inhibitors; Simvastatin; Thyroxine; Toothpastes; Xerostomia | 2020 |
Chemometric spectrophotometric methods for simultaneous estimation of metoprolol succinate and amlodipine besylate in their tablet formulation.
Topics: Amlodipine; Metoprolol; Spectrophotometry; Tablets | 2021 |
Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry Analysis.
Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Fluids; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Hypertension; Imidazoles; Liquid-Liquid Extraction; Metoprolol; Patient Compliance; Pilot Projects; Plasma; Reference Values; Reproducibility of Results; Tandem Mass Spectrometry; Tetrazoles | 2021 |
Zeolitic imidazolate framework-67-modified open-tubular column with cyclodextrin for enantioseparation in capillary electrochromatography.
Topics: Amlodipine; Atenolol; Capillary Electrochromatography; Cyclodextrins; Histidine; Metoprolol; Propranolol; Stereoisomerism; Zeolites | 2022 |
Blood pressure response to commonly administered antihypertensives for severe inpatient hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Carvedilol; Cohort Studies; Humans; Hydralazine; Hypertension; Inpatients; Metoprolol | 2022 |
Hair analysis for beta-blockers and calcium-channel blockers by using liquid chromatography-tandem mass spectrometry as a tool for monitoring adherence to antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Amlodipine; Antihypertensive Agents; Atenolol; Bisoprolol; Calcium; Calcium Channel Blockers; Chromatography, Liquid; Hair Analysis; Humans; Labetalol; Metoprolol; Nadolol; Nebivolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry | 2022 |
THE NITROSAMINE CONTAMINATION IN BETA BLOCKERS (BISOPROLOL/METOPROLOL), ACE INHIBITORS (LISINOPRIL/PERINDOPRIL), THIAZIDES DIURETICS (HCT), CALCIUM CHANNEL BLOCKERS (AMLODIPINE/FELODIPINE), SARTANS (CANDESARTAN) AND ТHE SUBSEQUENT SKIN CANCER DEVELOPMENT
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bisoprolol; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Felodipine; Humans; Lisinopril; Melanoma; Metoprolol; Nitrosamines; Perindopril; Prospective Studies; Skin Neoplasms; Sodium Chloride Symporter Inhibitors; Thiazides | 2023 |
Improvement in hemodynamics of amlodipine besylate combined with metoprolol in patients with hypertension complicated by heart failure.
Topics: Amlodipine; Heart Failure; Hemodynamics; Humans; Hypertension; Metoprolol | 2023 |