amlodipine and lovastatin

amlodipine has been researched along with lovastatin in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (15.38)	18.2507
2000's	4 (30.77)	29.6817
2010's	6 (46.15)	24.3611
2020's	1 (7.69)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chen, L; Haught, WH; Mehta, JL; Parathasarathy, S; Saldeen, TG; Yang, B	1
Akhmedzhanov, NM; Orekhov, AN; Pivovarova, EM; Sobenin, IA; Tertov, VV	1
Choi, MS; Kim, IS; Luo, Z; Rehman, SU; Xue, Y; Yao, G; Yoo, HH; Zhang, Y	1
Ahmad, S; Ali, N; Ali, W; Rahman, SU; Ullah, A	1

Reviews

1 review(s) available for amlodipine and lovastatin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for amlodipine and lovastatin

Article	Year
Antiatherosclerotic and antiatherogenic effects of a calcium antagonist plus statin combination: amlodipine and lovastatin. International journal of cardiology, 1997, Dec-31, Volume: 62 Suppl 2 Topics: Amlodipine; Anticholesteremic Agents; Aorta; Arteriosclerosis; Calcium Channel Blockers; Cell Division; Cells, Cultured; Cholesterol; Culture Media; Drug Therapy, Combination; Follow-Up Studies; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lovastatin; Middle Aged; Muscle, Smooth, Vascular; Treatment Outcome	1997

Article

Year

Antiatherosclerotic and antiatherogenic effects of a calcium antagonist plus statin combination: amlodipine and lovastatin.

International journal of cardiology, 1997, Dec-31, Volume: 62 Suppl 2

Topics: Amlodipine; Anticholesteremic Agents; Aorta; Arteriosclerosis; Calcium Channel Blockers; Cell Division; Cells, Cultured; Cholesterol; Culture Media; Drug Therapy, Combination; Follow-Up Studies; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lovastatin; Middle Aged; Muscle, Smooth, Vascular; Treatment Outcome

1997

Other Studies

11 other study(ies) available for amlodipine and lovastatin

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Preservation of endogenous antioxidant activity and inhibition of lipid peroxidation as common mechanisms of antiatherosclerotic effects of vitamin E, lovastatin and amlodipine. Journal of the American College of Cardiology, 1997, Volume: 30, Issue:2 Topics: Amlodipine; Animals; Anticholesteremic Agents; Antioxidants; Arteriosclerosis; Calcium Channel Blockers; Diet, Atherogenic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lovastatin; Rabbits; Superoxide Dismutase; Vitamin E	1997
In Vitro Assessment of CYP-Mediated Drug Interactions for Kinsenoside, an Antihyperlipidemic Candidate. Molecules (Basel, Switzerland), 2016, Jun-18, Volume: 21, Issue:6 Topics: 4-Butyrolactone; Amlodipine; Chromatography, Liquid; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Hypolipidemic Agents; Inactivation, Metabolic; Lovastatin; Microsomes, Liver; Monosaccharides; Substrate Specificity; Tandem Mass Spectrometry	2016
Pitavastatin and Lovastatin Exhibit Calcium Channel Blocking Activity Which Potentiate Vasorelaxant Effects of Amlodipine: A New Futuristic Dimension in Statin's Pleiotropy. Medicina (Kaunas, Lithuania), 2023, Oct-10, Volume: 59, Issue:10 Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Norepinephrine; Rabbits; Vasodilator Agents; Verapamil	2023