amlodipine and losartan

amlodipine has been researched along with losartan in 191 studies

Research

Studies (191)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (5.76)18.2507
2000's75 (39.27)29.6817
2010's85 (44.50)24.3611
2020's20 (10.47)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Trimarco, B1
Carney, S; Dahlöf, B; Lindholm, LH; Ostergren, J; Pentikäinen, PJ1
Alhenc Gelas, F; Huang, W; Osborne-Pellegrin, MJ1
Drewe, J; Gasser, P; Martina, B; Weinbacher, M1
Barnes, CC; Lacourcière, Y; Wilson, TW1
McAlister, FA; Sackett, D; Straus, S1
Aranda, P; Casado, S; Fernández-Andrade, C; Guerra, L; Iversen, B; Russo, D; Zucchelli, P1
Berg, KJ; Fauchald, P; Hartmann, A; Holdaas, H; Lund, K1
Sever, PS1
Anguita Sánchez, M1
Anderson, TJ; Charbonneau, F; Elstein, E; Haber, H1
Battegay, E; Dieterle, T; Martina, B; Weinbacher, M1
Grote, L; Hedner, J; Kraiczi, H; Peker, Y1
Bescós, M; Campistol, JM; Campos, B; Iñigo, P; Lario, S; Oppenheimer, F; Piera, C; Rivera, F1
Díez, J; González, A; Larman, M; López, B; Martínez Ubago, JL; Querejeta, R; Varo, N1
Liang, X; Su, M; Xie, X; Yu, G; Zhao, S1
Díez, J; Fortuño, MA; González, A; Larman, M; López, B; Querejeta, R; Ravassa, S1
Iwasaka, T; Masaki, H; Matsubara, H; Nishikawa, M; Nishiue, T; Shibasaki, Y1
Studney, D1
Kinoshita, M; Mabuchi, N; Maeda, K; Ohnishi, M; Tsutamoto, T; Tsutsui, T1
Draganov, B; Holdaas, H; Høieggen, A; Jenssen, T; Os, I; Stenehjem, A1
Iwasaka, T; Masaki, H; Matsubara, H; Nishiue, T; Shibasaki, Y1
Suzuki, H2
Gokhale, N; Pawar, D; Shahani, S1
Deanfield, JE1
Lester, MH; Resnick, LM1
Liang, XQ; Yu, GL; Zheng, JQ1
Xie, XM; Yu, GL; Zhou, P1
Bilen, H; Cetinkaya, R; Keles, S; Odabas, AR; Selcuk, Y1
Choi, KH; Choi, S; Goo, YS; Ha, SK; Han, DS; Kang, SW; Lee, HY; Park, HC; Xu, ZG1
Kawecka-Jaszcz, K; Klocek, M; Rajzer, M1
Bryce, A; Clarysse, L; Dass, B; Gamboa, R; Germano, G; Gilles, L; Gomez-Fernandez, P; Junren, Z; Kyle, C; Matadamas, N; Maxwell, T; Moreno-Heredia, E; Ortega-Gonzalez, G; Rodriguez, A; Rodriguez, F; Sanderson, JE; Smith, RD; Volpe, M1
Aguirre, R; Andrade, CF; Ara, JM; Arias, M; Bernis, C; Campistol, JM; Galceran, JM; Luño, J; Marín, R; Mora, J; Poveda, R; Praga, M; Prat, MV; Rivera, F1
Hayashi, M; Ideura, T; Iino, Y; Kawaguchi, Y; Kawamura, T; Kitajima, T; Koyama, A; Kuwahara, M; Shiigai, T; Sugisaki, T; Suzuki, H; Tomino, Y; Uchida, S; Umemura, S; Yamada, K; Yamazaki, T1
Chiang, HT; Lin, SL; Liu, CP; Wu, SC1
Ruilope, LM; Segura, J1
Ghosh, AK; Ghosh, K1
Hayashi, M; Ideura, T; Iino, Y; Kawaguchii, Y; Kawamura, T; Kitajima, T; Koyama, A; Kuwahara, M; Shiigai, T; Sugisaki, T; Suzuki, H; Tomino, Y; Uchida, S; Umemura, S; Yamada, K; Yamazaki, T1
Bomalaski, JS; Clark, MA1
Aralica, G; Batelja, L; Blagaic, AB; Hanzevacki, JS; Konjevoda, P; Kusec, V; Lovric-Bencic, M; Rogic, D; Seiwerth, S; Sikiric, P1
Lindholm, LH1
Brown, CA; Brown, SA; Cartier, LM; Dietrich, UM; Mathur, S; Munday, JS; Newell, MA; Sheldon, SE1
Buniatian, MS; Oshchepkova, EV; Rogoza, AN; Zelveian, PA1
Iwai, K; Matsumoto, M; Morimoto, S1
Ando, D; Hirawa, N; Tochikubo, O; Umemura, S; Yasuda, G1
Dikmen, T; Gul, S; Kaynar, K; Ovali, E; Ulusoy, S; Vanizor, B1
Alvarez, V; Arias, M; Campistol, JM; Coto, E; Fernández Andrade, C; Galcerán, JM; Luño, J; Marín, R; Poveda, R; Praga, M; Rivera, F; Vallés, M1
de Cavanagh, EM; Ferder, L; Inserra, F; Piotrkowski, B; Stella, I; Toblli, JE1
Corradi, L; Destro, M; Fogari, E; Fogari, R; Mugellini, A; Rinaldi, A; Zoppi, A1
Bia, MJ; Eisen, T; Formica, RN; Friedman, AL; Lorber, MI; Smith, JD1
Iwasaka, T; Masaki, H; Matsubara, H; Matsumoto, N; Mori, Y; Nishikawa, M; Nishiue, T; Shibasaki, Y; Tamura, K1
Egido, J; García-Puig, J; Gómez-Garre, D; Granados, R; Martín-Ventura, JL; Ruano, M; Sancho, T; Torres, R1
Dallaverde, E; Feitosa, GS; Gomes, MA; Kohlmann, O; Mion, D; Oigman, W; Ribeiro, AB; Rocha, JC; Salgado, N1
Rodriguez-Iturbe, B1
Calabrò, R; Natale, F; Tedesco, MA1
Kawano, Y1
Aksnes, TA; Guptha, S; Kjeldsen, SE; Moan, A; Os, I; Reims, HM1
Coelho, EB; da Silva, CA; Fazan, R; Nobre, F; Salgado, HC1
Fukuoka, T; Higaki, J; Irita, J; Kurata, M; Manabe, S; Miyoshi, K; Murakami, K; Okura, T; Watanabe, S1
Jin, HM; Pan, Y1
Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Miettinen, HE; Paavonen, KJ; Pentikäinen, PJ; Strandberg, T; Suonsyrjä, T; Tikkanen, I; Tilvis, R; Virolainen, J1
Abe, C; Akashiba, A; Ishimitsu, T; Kameda, T; Matsuoka, H; Minami, J; Takahashi, T1
Chiara Cavallini, M; Palmieri, V; Pini, R1
Hori, M; Yamamoto, K1
Arora, R; Prabhakar, H; Rath, GP1
de Cavanagh, EM; Ferder, L; Fraga, CG; Inserra, F; Piotrkowski, B; Stella, I; Toblli, JE1
Fujita, T; Gohchi, K; Shimosawa, T; Yatomi, Y1
Donner, K; Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Miettinen, HE; Paavonen, KJ; Pentikäinen, PJ; Strandberg, T; Suonsyrjä, T; Tikkanen, I; Tilvis, R1
Dabek, J; Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Nieminen, MS; Oikarinen, L; Porthan, K; Suonsyrja, T; Toivonen, L; Vaananen, H; Viitasalo, M; Virolainen, J1
Aksnes, TA; Flaa, A; Kjeldsen, SE; Mundal, HH; Rostrup, M; Sevre, K1
Mourad, JJ; Waeber, B1
Gregg, AM; Kloner, RA; Neutel, J; Roth, EM; Schwartz, B; Shi, H; Thakker, KM; Weinberger, MH; Weiss, R1
Kuroyanagi, A; Matsubara, H; Sakamoto, T; Shiraishi, H; Shirayama, T1
Higuchi, C; Naito, T; Nishimura, H; Otsuka, K; Sanaka, T; Tanihata, Y1
Donner, K; Fodstad, H; Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Suonsyrjä, T1
Hamamoto, Y; Honjo, S; Ikeda, H; Koshiyama, H; Minamikawa, J; Nabe, K; Nakamura, Y; Wada, Y1
Guo, LL; Jin, HM; Pan, Y1
Ahn, BO; Choi, SM; Kang, KK; Kim, JH; Seo, MJ; Yoo, M1
Antikainen, M; Donner, KM; Hannila-Handelberg, T; Hiltunen, TP; Hirvonen, A; Kontula, K; Suonsyrjä, T; Tikkanen, I1
Ando, C; Inoue, Y; Kodama, S; Mihara, H; Miyoshi, K; Niimura, H; Okamura, K; Sumi, S; Tojyo, H; Tsuchiya, Y; Urata, H; Yamanouchi, Y1
Chandurkar, NB; Gupta, BS; Pareek, A; Sharma, R; Tiwari, D1
Gleim, GW; Lam, C; Loeys, T; Manas, D; Santoro, E; Shahinfar, S; Strehlau, J; Webb, NJ; Wells, TG1
Derosa, G; Fogari, R; Mugellini, A; Preti, P; Zoppi, A1
Horio, T; Iwashima, Y; Kamide, K; Kawano, Y; Nakamura, S; Yoshihara, F1
Bilo, G; Mancia, G; Parati, G; Schumacher, H1
Goda, A; Hirotani, S; Lee-Kawabata, M; Masuyama, T; Matsumoto, M; Naito, Y; Nakaboh, A; Ohyanagi, M; Otsuka, M; Tsujino, T; Yoshida, C1
Chayama, K; Fujii, Y; Fujimura, N; Hata, T; Hidaka, T; Higashi, Y; Idei, N; Kato, H; Kihara, Y; Liao, JK; Maruhashi, T; Mikami, S; Noma, K; Soga, J1
Akehi, N; Ebisuno, S; Fukui, S; Hori, M; Horiguchi, Y; Katsube, Y; Kobayashi, K; Kodama, M; Ohtsu, H; Ota, M; Ozaki, H; Sakai, A; Shimonagata, T; Takayasu, K; Yamamoto, K; Yamazaki, T1
Divya, O; Nagavalli, D; Sankar, AS; Santha, A; Vaidhyalingam, V1
Gleim, GW; Lam, C; Le Bailly De Tilleghem, C; Shahinfar, S; Strehlau, J; Webb, NJ; Wells, TG1
Hosseini, F; Mahmoudian, M; Nemati, F; Rahbar-Roshandel, N; Shafiei, M1
Berl, T; de Graeff, PA; de Zeeuw, D; Holtkamp, FA; Lambers Heerspink, HJ; Laverman, GD; Lewis, JB; Packham, D; Parving, HH; Remuzzi, G1
Balink, H; de Graaf, W; Grond, J; Hemmelder, MH1
Corradi, L; Derosa, G; Destro, M; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Zoppi, A1
Duprez, D; Ferdinand, KC; Purkayastha, D; Samuel, R; Wright, RF1
Arimanickam, G1
Khan, BV1
Kawecka-Jaszcz, K; Rajzer, M; Undas, A; Wojciechowska, W1
Donner, KM; Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Suonsyrjä, T1
Derosa, G; Fogari, R; Lazzari, P; Maffioli, P; Mugellini, A; Zoppi, A1
Chae, SC; Cho, SY; Hong, TJ; Jeong, JW; Jung, JW; Kang, SM; Kim, CH; Kim, JJ; Kim, MH; Kwon, J; Park, CG; Park, SH; Shin, DG; Yang, JY; Yoon, JH; Youn, JC1
Duprez, D; Ferdinand, K; Purkayastha, D; Samuel, R; Wright, R1
Chae, SC; Cho, SY; Choi, YJ; Hong, BK; Hong, TJ; Jeong, JW; Kim, CH; Kim, JJ; Kim, MH; Kwan, J; Park, CG; Park, SH; Yang, JY; Youn, HJ1
Berwanger, O; Mion Júnior, D; Ortega, KC; Silva, GV; Tsuji, RL1
Chen, S; Cui, Y; Jiang, J; Peng, J; Shen, J; Wang, W; Wu, Q1
Cho, SY; Choi, YJ; Hong, BK; Kim, KS; Park, CG; Yang, JY; Yoon, HJ; Yoon, JH; Yoon, MH1
Eguchi, K; Fukutomi, M; Hoshide, S; Kabutoya, T; Kario, K; Watanabe, T1
Morris, JK; Wald, DS; Wald, NJ1
Lin, J; Lin, L; Peng, F; Tang, H1
Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T1
Eguchi, K; Fukutomi, M; Hoshide, S; Kario, K; Watanabe, T1
Ayaori, M; Higashi, K; Hosoai, H; Ikewaki, K; Kijima, F; Nakamura, H; Nashida, Y; Nishiwaki, M; Shige, H; Shimizu, S; Yamashita, T; Yokoyama, M1
Boytsov, S; Deev, A; Dupik, N; Kolos, I; Loukianov, M1
Hasebe, N; Kikuchi, K; Koyama, S; Maruyama, J; Morimoto, H; Morita, K; Saijo, Y; Sano, H; Sasagawa, Y; Sato, N; Sumitomo, K; Takehara, N; Takeuchi, T2
Hayashi, S; Horio, T; Iwashima, Y; Kamide, K; Kawano, Y; Matayoshi, T; Nakamura, S; Ohta, Y; Takiuchi, S; Yoshihara, F1
He, DH; Lin, JX; Ning, RB; Wang, HJ; Xu, CS; Zhang, LM1
Soucek, M; Spinar, J; Vitovec, J1
Pérez Carreño, JG; Romero, JD; Villar Centeno, JC1
Dobrokhod, AS; Kushnir, SM; Radchenko, GD; Sirenko, YM; Torbas, OO1
Guo, R; Li, R; Lv, C; Wang, B; Wang, X; Wei, C; Yao, H1
Hong, YH; Kwon, HM; Lee, YS; Lim, JS; Nam, H; Shin, JW1
He, DH; Lin, JX; Lin, LM; Ning, RB; Wang, HJ; Xu, CS; Zhang, LM1
Chazova, IE; Martyniuk, TV1
Lawrence Gould, A; Unniachan, S; Wu, D1
Jeffers, BW; Wang, JG; Yan, P1
Bedirian, R; Gismondi, RA; Ladeira, MC; Neves, MF; Oigman, W; Pozzobon, CR2
Fujita, KP; Hanson, ME; Rajagopalan, S; Unniachan, S; Wu, D1
Ahn, T; Bae, JH; Han, KR; Hyon, MS; Kim, WH; Kim, YK; Lee, SU; Lim, DS; Park, HK; Suh, SY1
Azuma, K; Fujita, KP; Nishida, C; Numaguchi, H; Rakugi, H; Shimada, K; Shirakawa, M; Tsuchihashi, T; Yamaguchi, H2
Nagata, M; Takase, B1
Fu, SK; Gu, HF; Hu, C; Jin, HM; Liu, XL; Pan, LH; Pan, Y; Qiao, QY; Zhou, DC1
Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Donner, KM; Frau, F; Glorioso, N; Glorioso, V; Gong, Y; Gums, JG; Hiltunen, TP; Johnson, JA; Kontula, KK; Ripatti, S; Saarela, J; Salvi, E; Sarin, AP; Turner, ST; Zaninello, R1
Hayashi, M; Iino, Y; Kawamura, T; Kuwahara, M; Nangaku, M; Uchida, S1
Bazaeva, EV; Boitsov, SA; Drapkina, OM; Luk'ianov, MM; Panov, AV; Shchukina, GN; Terent'ev, BP; Tiurin, VP1
He, D; Lin, J; Zhang, L1
Ishii, K; Ito, H; Iwakura, K; Kihara, H; Toh, N; Watanabe, H; Yoshikawa, J1
Luteijn, JM; Morris, JK; Oppenheimer, P; Taylor, D; Wald, NJ1
Brunette-Lawrey, E; Croft, F1
Kotegawa, T; Koya, Y; Machi, Y; Namiki, N; Shobu, Y; Uchida, S1
Cho, SM; Choi, Y; Jang, IJ; Kang, WH; Lee, S; Nam, KY; Yu, KS1
Duran-Salgado, MB; Elizalde-Barrera, CI; Garro-Almendaro, AK; Rubio-Guerra, AF; Suarez-Cuenca, JA1
Bhagat, S; Bharatam, PV; Chakraborti, AK; Handa, T; Jhajra, S; Singh, S1
Agarwal, I; Ferket, BS; Fleischmann, KE; Hunink, MG; Khanji, M; Petersen, SE1
de Leeuw, PW; Fagard, R; Kroon, AA1
Al-Sharea, A; Dart, AM; Du, XJ; Gao, XM; Han, LP; Kiriazis, H; Moore, S; Murphy, AJ; Su, Y; Tsai, A1
Fendrikova, AV; Pyhalova, NE; Sirotenko, DV; Skibitsky, VV1
Alves, PH; Castro, CH; Colugnati, DB; Macedo, LM; Mendes, EP; Nunes, AD; Pedrino, GR; Santos, RA; Souza, AP1
Chae, JK; Chae, SC; Chang, KY; Cho, JR; Choi, JH; Choi, YJ; Chun, KJ; Han, KR; Han, SH; Heo, JH; Hong, BK; Hong, SJ; Jeong, HS; Jeong, MH; Jung, J; Kang, HJ; Kang, SM; Kim, CH; Kim, DW; Kim, JJ; Kim, KS; Kim, SH; Kim, WS; Kim, YD; Kwan, J; Lee, BK; Lee, SK; Lee, SU; Park, CG; Park, SH; Shin, DG; Shin, JH; Won, KH1
Cha, DH; Choi, JH; Choi, JY; Choi, KJ; Choi, SW; Hong, TJ; Jung, HO; Kim, KH; Kim, SM; Kim, SY; Kim, WS; Lee, HY; Lee, KJ; Oh, JH; Park, DG; Park, SW; Park, TH; Rha, SW; Rhee, MY; Ryu, DR; Shim, J; Song, PS; Yoo, BS1
Brown, MJ; Caulfield, M; Cruickshank, JK; Ford, I; MacDonald, TM; Mackenzie, IS; McCann, GP; McInnes, G; Morant, S; Padmanabhan, S; Salsbury, J; Sever, P; Webb, DJ; Williams, B1
Barnes, AP; Ellison, DH; Ferdaus, MZ; Kaul, S; McCormick, JA; Minnier, J; Nelson, JW1
Ashcroft, JA1
Ahn, YK; Chae, SC; Cho, EJ; Cho, MC; Choi, DJ; Chung, WJ; Ha, JW; Hong, SJ; Hong, TJ; Kim, CJ; Kim, SK; Kim, YJ; Lee, HY; Park, CG; Park, S; Shin, J; Sohn, IS; Sung, KC; Yoo, BS; Youn, HJ2
Hebibovic, S; Jatic, Z; Rustempasic, E; Skopljak, A; Sukalo, A; Valjevac, A1
Blot, WJ; Gonzales, H; Miller, R; Muñoz, D; Munro, H; Pappalardo, S; Reynolds, C; Song, W; Tousey, P; Uzoije, P; Walkley, D; Wang, TJ; White, C1
Agabiti-Rosei, C; De Ciuceis, C; Paini, A; Rizzoni, D; Salvetti, M1
Einollahi, B; Ghahroudi, MS; Hosseini, MS; Jafari, R; Javanbakht, M; Nikpoor, M; Rostami, Z1
Chung, JY; Jang, IJ; Jung, JA; Kim, YI; Park, SI; Yoon, DY1
Ahn, MS; Ahn, SG; Choi, E; Hong, KS; Kim, JY; Lee, JW; Lee, SH; Park, SM; Ryu, DR; Son, JW; Yoo, BS; Yoon, J; Youn, YJ1
Glick, A; Johnson, C; Sista, V1
Hong, SJ; Kim, HY; Kim, SY; Kim, W; Lim, SW; Park, S; Rhee, MY; Shin, J; Sung, KC1
Macaulay, TE; Sheridan, E; Ward, S1
Ahangari Maleki, M; Ansarin, K; Esmailnajad, A; Haghdoost, M; Kalami, N; Maleki, M; Nouri-Vaskeh, M; Rezaee, H; Sadeghi, A; Saleh, P; Sharifi, A; Soroureddin, Z; Taghizadieh, A; Varshochi, M; Zand, R1
Aung, TKK; Chua, MWJ; Chuah, TY1
Choi, Y; Chung, JY; Jeon, I; Jung, J; Moon, SJ; Park, SI; Yu, KS1
Dabertrand, F; Ferris, HR; Greenstein, AS; Harraz, OF; Hill-Eubanks, DC; Koide, M; Longden, TA; Nelson, MT; Wellman, GC1
An, H; Choi, J; Joo, HJ; Kim, EJ; Kim, YH; Lee, J; Yum, Y1
Al-Mohammadi, OS; Al-Qaaneh, AM; Mustafa, SM; Obaid, WT; Rabaan, AA1
Le Corre, P; Loas, G1
Ankrah, D; Hollingworth, SA; Okeke, CC; Ruiz, F; Thacher, E; Uzochukwu, BSC1
A Wartolowska, K; André, E; Biessels, GJ; Bousser, MG; Dichgans, M; Duering, M; Kerkhofs, D; Kopczak, A; Mansmann, U; Middeke, M; N Doubal, F; Norrving, B; Onkenhout, L; Rothwell, PM; S Stringer, M; Staals, J; Thrippleton, MJ; van den Brink, H; van Dinther, M; van Oostenbrugge, R; W Blair, G; Wardlaw, JM; Webb, AJ1
Cho, DK; Cho, GY; Cho, JM; Heo, JH; Hong, SJ; Jeong, MH; Jung, JA; Kim, DH; Kim, SH; Kim, SY; Kim, W; Kwon, K; Lee, HY; Lee, JB; Lim, SW; Park, K; Park, S; Pyun, WB; Rha, SW; Rhee, MY; Shin, J; Sung, KC1
Al Khawaja, AY; Hamdan, II; Khalil, EA; Mansour, RSH1
Ahn, Y; Chae, IH; Hong, SJ; Hong, TJ; Kang, DH; Kim, BK; Kim, H; Kim, HS; Kim, MC; Kim, MH; Kim, SH; Kim, SY; Kim, W; Rhee, MY1
Liang, H; Tang, T; Xie, M1
Tchernev, G1

Reviews

18 review(s) available for amlodipine and losartan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Angiotensin blockade in type 2 diabetes: what the new evidence tells us about renal and cardiac complications.
    The Canadian journal of cardiology, 2002, Volume: 18 Suppl A

    Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Humans; Irbesartan; Kidney Diseases; Losartan; Prognosis; Ramipril; Tetrazoles

2002
[Type 2 diabetes and nephropathy--new studies, new treatment strategies?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2002, Apr-10, Volume: 122, Issue:9

    Topics: Amlodipine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Losartan; Randomized Controlled Trials as Topic; Renin-Angiotensin System

2002
[Large scale clinical trials in prevention of end-stage renal disease due to type 2 diabetes with angiotensin receptor antagonists].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:10

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles

2002
[Evidence for the benefits of ACE inhibitors and AII antagonists in slowing progressive renal failure in diabetes].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 10

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Captopril; Clinical Trials as Topic; Disease Progression; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Tetrazoles; Treatment Outcome

2002
Losartan and other angiotensin II antagonists for nephropathy in type 2 diabetes mellitus: a review of the clinical trial evidence.
    Clinical therapeutics, 2003, Volume: 25, Issue:12

    Topics: Albuminuria; Amlodipine; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Proteinuria; Tetrazoles

2003
Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase.
    Current rheumatology reports, 2004, Volume: 6, Issue:3

    Topics: Allopurinol; Amlodipine; Clinical Trials as Topic; Enzyme Inhibitors; Febuxostat; Gout; Humans; Hyperuricemia; Losartan; Pyrazoles; Thiazoles; Treatment Outcome; Urate Oxidase; Uric Acid; Xanthine Oxidase

2004
[Treatment of hypertension in elderly patients with coronary heart disease].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Coronary Disease; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Treatment Outcome

2005
[HOSP study].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 6

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Humans; Hypertension; Japan; Losartan; Middle Aged; Randomized Controlled Trials as Topic

2006
[J-ELAN study (effect of losartan and amlodipine on left ventricular diastolic function in patients with mild-to-moderate hypertension)].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Apr-28, Volume: 65 Suppl 4

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan

2007
Evaluating 24-h antihypertensive efficacy by the smoothness index: a meta-analysis of an ambulatory blood pressure monitoring database.
    Journal of hypertension, 2010, Volume: 28, Issue:11

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Databases, Factual; Female; Humans; Losartan; Male; Ramipril; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2010
Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials.
    European heart journal, 2011, Volume: 32, Issue:12

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Stroke; Tetrazoles; Treatment Outcome

2011
The effect of amlodipine besylate, losartan potassium, olmesartan medoxomil, and other antihypertensives on central aortic blood pressure and biomarkers of vascular function.
    Therapeutic advances in cardiovascular disease, 2011, Volume: 5, Issue:5

    Topics: Amlodipine; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Losartan; Olmesartan Medoxomil; Reproducibility of Results; Tetrazoles

2011
Indirect treatment comparison between fixed-dose-combinations of amlodipine/losartan and amlodipine/valsartan in blood pressure control.
    International journal of clinical practice, 2014, Volume: 68, Issue:2

    Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome

2014
Effects of amlodipine and other classes of antihypertensive drugs on long-term blood pressure variability: evidence from randomized controlled trials.
    Journal of the American Society of Hypertension : JASH, 2014, Volume: 8, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Enalapril; Humans; Hypertension; Lisinopril; Losartan; Randomized Controlled Trials as Topic

2014
Evaluation of blood pressure reduction response and responder characteristics to fixed-dose combination treatment of amlodipine and losartan: a post hoc analysis of pooled clinical trials.
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:9

    Topics: Adult; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diastole; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Republic of Korea; Systole; Treatment Outcome

2014
Reconsidering the Polypill for Management of Cardiovascular Risk Factors in Underserved Patients.
    Current cardiology reports, 2021, 02-17, Volume: 23, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Drug Combinations; Heart Disease Risk Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Risk Factors; Vulnerable Populations

2021
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
    Clinical cardiology, 2023, Volume: 46, Issue:8

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Network Meta-Analysis; Telmisartan; Tetrazoles; Valine; Valsartan

2023

Trials

106 trial(s) available for amlodipine and losartan

ArticleYear
[The first clinical experience in Italy with angiotensin II receptor antagonists: results of a multicenter study on the efficacy and tolerance in arterial hypertension].
    Cardiologia (Rome, Italy), 1995, Volume: 40, Issue:12 Suppl 1

    Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Italy; Losartan; Male; Middle Aged; Tetrazoles

1995
Main results of the losartan versus amlodipine (LOA) study on drug tolerability and psychological general well-being. LOA Study Group.
    Journal of hypertension, 1997, Volume: 15, Issue:11

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Middle Aged; Quality of Life

1997
Effects of losartan titrated to losartan/hydrochlorothiazide and amlodipine on blood pressure and peripheral capillary microcirculation in patients with mild-to-moderate hypertension.
    Journal of human hypertension, 1998, Volume: 12, Issue:7

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Capillaries; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Microcirculation; Middle Aged

1998
The antihypertensive efficacy of losartan and amlodipine assessed with office and ambulatory blood pressure monitoring. Canadian Cozaar Hyzaar Amlodipine Trial Study Group.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1998, Sep-08, Volume: 159, Issue:5

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Office Visits

1998
Comparison of losartan and amlodipine in renally impaired hypertensive patients.
    Kidney international. Supplement, 1998, Volume: 68

    Topics: Adult; Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium; Creatine; Female; Humans; Hypertension, Renal; Losartan; Male; Middle Aged

1998
Renal effects of losartan and amlodipine in hypertensive patients with non-diabetic nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:12

    Topics: Adult; Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Biomarkers; Blood Pressure; Cross-Over Studies; Dextrans; Double-Blind Method; Female; Humans; Hypertension; Kidney; Kidney Diseases; Losartan; Middle Aged; Prospective Studies; Proteinuria

1998
Comparative study of ACE-inhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study)
    Journal of the American College of Cardiology, 2000, Volume: 35, Issue:1

    Topics: Aged; Amlodipine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Drug Therapy, Combination; Enalapril; Endothelium, Vascular; Female; Humans; Isoquinolines; Losartan; Male; Middle Aged; Quinapril; Tetrahydroisoquinolines; Vasodilation

2000
Effects of losartan titrated to Losartan/Hydrochlorothiazide and amlodipine on left ventricular mass in patients with mild-to-moderate hypertension. A double-blind randomized controlled study.
    Cardiology, 1999, Volume: 92, Issue:2

    Topics: Adult; Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Body Mass Index; Double-Blind Method; Echocardiography; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Treatment Outcome

1999
Comparison of atenolol, amlodipine, enalapril, hydrochlorothiazide, and losartan for antihypertensive treatment in patients with obstructive sleep apnea.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Single-Blind Method; Sleep Apnea, Obstructive; Sodium Chloride Symporter Inhibitors

2000
Effects of losartan and amlodipine on intrarenal hemodynamics and TGF-beta(1) plasma levels in a crossover trial in renal transplant recipients.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:4

    Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Endothelin-1; Female; Hemodynamics; Humans; Kidney; Kidney Transplantation; Losartan; Male; Middle Aged; Renal Circulation; Renin; Transforming Growth Factor beta; Transforming Growth Factor beta1

2001
Usefulness of serum carboxy-terminal propeptide of procollagen type I in assessment of the cardioreparative ability of antihypertensive treatment in hypertensive patients.
    Circulation, 2001, Jul-17, Volume: 104, Issue:3

    Topics: Adult; Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biopsy; Blood Pressure; Collagen; Endomyocardial Fibrosis; Female; Heart; Humans; Hypertension; Losartan; Male; Middle Aged; Myocardium; Patient Compliance; Peptide Fragments; Predictive Value of Tests; Procollagen; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Remission Induction; Treatment Outcome; Ventricular Function, Left; White People

2001
Stimulation of cardiac apoptosis in essential hypertension: potential role of angiotensin II.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:1

    Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Calcium Channel Blockers; Female; Heart Ventricles; Humans; Hypertension; Losartan; Male; Middle Aged; Myocardium; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptor, Angiotensin, Type 1

2002
Angiotensin II type 1 receptor antagonist, losartan, causes regression of left ventricular hypertrophy in end-stage renal disease.
    Nephron, 2002, Volume: 90, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Echocardiography; Enalapril; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Dialysis

2002
[Angiotensin II type 1 antagonist suppress left ventricular hypertrophy and myocardial fibrosis in patient with end stage renal disease (ESRD)].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:10

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Cardiomyopathies; Enalapril; Female; Fibrosis; Humans; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Myocardium; Renal Dialysis

2002
Efficacy and safety of losartan-amplodipine combination--an Indian postmarketing surveillance experience.
    Journal of the Indian Medical Association, 2002, Volume: 100, Issue:3

    Topics: Adult; Aged; Amlodipine; Blood Pressure Determination; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; India; Losartan; Male; Middle Aged; Product Surveillance, Postmarketing; Treatment Outcome

2002
[Effect of losartan and amilodipine on the platelet activation and renal function in patients with mild and moderate hypertension].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2002, Apr-28, Volume: 27, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Female; Humans; Hypertension; Kidney; Kidney Function Tests; Losartan; Male; Middle Aged; P-Selectin; Platelet Activation

2002
The effect of high dose losartan on erythropoietin resistance in patients undergoing haemodialysis.
    Panminerva medica, 2003, Volume: 45, Issue:1

    Topics: Adult; Amlodipine; Anemia; Angiotensin Receptor Antagonists; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Resistance; Erythropoietin; Female; Humans; Hypertension; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Prospective Studies; Recombinant Proteins; Renal Dialysis

2003
Effect of losartan and amlodipine on proteinuria and transforming growth factor-beta1 in patients with IgA nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:6

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Glomerulonephritis, IGA; Humans; Hypertension; Losartan; Male; Middle Aged; Proteinuria; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Outcome

2003
Effect of amlodipine, quinapril, and losartan on pulse wave velocity and plasma collagen markers in patients with mild-to-moderate arterial hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:6

    Topics: Adult; Aldosterone; Amlodipine; Antihypertensive Agents; Biomarkers; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Collagen; Compliance; Echocardiography; Elasticity; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Pulsatile Flow; Quinapril; Severity of Illness Index; Tetrahydroisoquinolines

2003
Comparison of the blood pressure-lowering effects and tolerability of Losartan- and Amlodipine-based regimens in patients with isolated systolic hypertension.
    Clinical therapeutics, 2003, Volume: 25, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged

2003
Antiproteinuric efficacy of losartan in comparison with amlodipine in non-diabetic proteinuric renal diseases: a double-blind, randomized clinical trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:9

    Topics: Adult; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus; Double-Blind Method; Female; Humans; Kidney Diseases; Losartan; Male; Middle Aged; Prospective Studies; Proteinuria; Transforming Growth Factor beta; Treatment Outcome

2003
Interim evidence of the renoprotective effect of the angiotensin II receptor antagonist losartan versus the calcium channel blocker amlodipine in patients with chronic kidney disease and hypertension: a report of the Japanese Losartan Therapy Intended for
    Clinical and experimental nephrology, 2003, Volume: 7, Issue:3

    Topics: Adult; Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension, Renal; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Proteinuria

2003
Prospective and randomized study of the antihypertensive effect and tolerability of three antihypertensive agents, losartan, amlodipine, and lisinopril, in hypertensive patients.
    Heart and vessels, 2004, Volume: 19, Issue:1

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cough; Female; Humans; Lisinopril; Losartan; Male; Middle Aged; Prospective Studies

2004
Renoprotective effect of losartan in comparison to amlodipine in patients with chronic kidney disease and hypertension--a report of the Japanese Losartan Therapy Intended for the Global Renal Protection in Hypertensive Patients (JLIGHT) study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Female; Humans; Hypertension, Renal; Japan; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Proteinuria; Treatment Outcome

2004
Effects of losartan and amlodipine on urinary albumin excretion and ambulatory blood pressure in hypertensive type 2 diabetic patients with overt nephropathy.
    Diabetes care, 2005, Volume: 28, Issue:8

    Topics: Adult; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Middle Aged

2005
Effect of losartan and amlodipine on left ventricular diastolic function in patients with mild-to-moderate hypertension (J-ELAN): rationale and design.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:1

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Patient Selection; Research Design; Ventricular Dysfunction, Left

2006
Losartan and prevention of atrial fibrillation recurrence in hypertensive patients.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Losartan; Male; Middle Aged; Recurrence

2006
A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:5

    Topics: Adult; Aged; Amlodipine; Blood Pressure Determination; Chi-Square Distribution; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Kidney Failure, Chronic; Kidney Transplantation; Losartan; Male; Middle Aged; Probability; Risk Assessment; Severity of Illness Index; Treatment Outcome

2006
Impact of the angiotensin II receptor antagonist, losartan, on myocardial fibrosis in patients with end-stage renal disease: assessment by ultrasonic integrated backscatter and biochemical markers.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:10

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Collagen; Double-Blind Method; Echocardiography; Enalapril; Female; Fibrosis; Humans; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Myocardium; Peptide Fragments; Procollagen

2005
Losartan improves resistance artery lesions and prevents CTGF and TGF-beta production in mild hypertensive patients.
    Kidney international, 2006, Volume: 69, Issue:7

    Topics: Adult; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Connective Tissue Growth Factor; Humans; Hypertension; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Losartan; Middle Aged; Reference Values; Transforming Growth Factor beta; Vascular Resistance

2006
[The "LOTHAR" study: evaluation of efficacy and tolerability of the fixed combination of amlodipine and losartan in the treatment of essential hypertension].
    Arquivos brasileiros de cardiologia, 2006, Volume: 86, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Glucose; Humans; Hypertension; Lipid Metabolism; Losartan; Male; Middle Aged; Statistics, Nonparametric; Time Factors

2006
Effects of monotherapy and combination therapy on blood pressure control and target organ damage: a randomized prospective intervention study in a large population of hypertensive patients.
    Journal of clinical hypertension (Greenwich, Conn.), 2006, Volume: 8, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carbazoles; Cardiovascular Diseases; Carvedilol; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Losartan; Male; Middle Aged; Propanolamines; Ultrasonography

2006
Improved insulin sensitivity with the angiotensin II-receptor blocker losartan in patients with hypertension and other cardiovascular risk factors.
    Journal of human hypertension, 2006, Volume: 20, Issue:11

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Cross-Over Studies; Double-Blind Method; Female; Glucose Clamp Technique; Heart Rate; Humans; Hypertension; Insulin; Insulin Resistance; Lipids; Losartan; Male; Middle Aged; Risk Factors; Treatment Outcome; Uric Acid; Vasodilation

2006
The effect of losartan and amlodipine on serum adiponectin in Japanese adults with essential hypertension.
    Clinical therapeutics, 2006, Volume: 28, Issue:10

    Topics: Adiponectin; Adult; Aged; Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies

2006
Angiotensin type-1 receptor blockade with losartan increases insulin sensitivity and improves glucose homeostasis in subjects with type 2 diabetes and nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:7

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Glucose; C-Peptide; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fasting; Female; Glycated Hemoglobin; Homeostasis; Humans; Insulin; Insulin Resistance; Losartan; Male; Middle Aged; Proteinuria; Time Factors; Treatment Outcome

2007
Predictors of antihypertensive drug responses: initial data from a placebo-controlled, randomized, cross-over study with four antihypertensive drugs (The GENRES Study).
    American journal of hypertension, 2007, Volume: 20, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Therapy, Combination; Finland; Genetic Variation; Genotype; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Phenotype; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Time Factors; Treatment Outcome

2007
Long-term efficacy of combination therapy with losartan and low-dose hydrochlorothiazide in patients with uncontrolled hypertension.
    International heart journal, 2007, Volume: 48, Issue:2

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Treatment Outcome

2007
Effectiveness of add-on low-dose diuretics in combination therapy for hypertension: losartan/hydrochlorothiazide vs. candesartan/amlodipine.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Benzimidazoles; Biphenyl Compounds; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome

2007
Laboratory tests as predictors of the antihypertensive effects of amlodipine, bisoprolol, hydrochlorothiazide and losartan in men: results from the randomized, double-blind, crossover GENRES Study.
    Journal of hypertension, 2008, Volume: 26, Issue:6

    Topics: Adult; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Calcium; Cross-Over Studies; Double-Blind Method; Forecasting; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Renin; Sodium; Treatment Outcome

2008
Short-term electrophysiological effects of losartan, bisoprolol, amlodipine, and hydrochlorothiazide in hypertensive men.
    Annals of medicine, 2009, Volume: 41, Issue:1

    Topics: Action Potentials; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electrocardiography; Electrophysiology; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Time Factors; Treatment Outcome; Ventricular Function

2009
Effects on plasma noradrenaline may explain some of the improved insulin sensitivity seen by AT-1 receptor blockade.
    Blood pressure, 2008, Volume: 17, Issue:3

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Insulin Resistance; Losartan; Male; Middle Aged; Norepinephrine; Sensitivity and Specificity; Treatment Outcome

2008
Blood pressure control with amlodipine add-on therapy in patients with hypertension and diabetes: results of the Amlodipine Diabetic Hypertension Efficacy Response Evaluation Trial.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:11

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Quinapril; Tetrahydroisoquinolines

2008
Losartan decreased premature ventricular contractions in patients with hypertension.
    Journal of human hypertension, 2009, Volume: 23, Issue:4

    Topics: Aged; Amlodipine; Anti-Arrhythmia Agents; Enalapril; Humans; Hypertension; Losartan; Middle Aged; Ventricular Premature Complexes

2009
Losartan elevates the serum high-molecular weight-adiponectin isoform and concurrently improves insulin sensitivity in patients with impaired glucose metabolism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:8

    Topics: Adiponectin; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Glucose Intolerance; Humans; Insulin Resistance; Losartan; Male; Middle Aged; Molecular Weight; Receptors, Cell Surface; Renin-Angiotensin System; Treatment Outcome

2008
Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study.
    American journal of hypertension, 2009, Volume: 22, Issue:2

    Topics: Adult; Amlodipine; Angiotensinogen; Antihypertensive Agents; Bisoprolol; Blood Pressure; Calmodulin-Binding Proteins; Humans; Hydrochlorothiazide; Losartan; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System

2009
Comparison of effects of amlodipine and angiotensin receptor blockers on the intima-media thickness of carotid arterial wall (AAA study: amlodipine vs. ARB in atherosclerosis study).
    Diabetes research and clinical practice, 2009, Volume: 83, Issue:1

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Carotid Arteries; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Tunica Intima; Tunica Media

2009
Adiponectin is positively associated with insulin resistance in subjects with type 2 diabetic nephropathy and effects of angiotensin II type 1 receptor blocker losartan.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:6

    Topics: Adiponectin; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Humans; Insulin; Insulin Resistance; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Proteinuria; Renal Insufficiency, Chronic; Renin-Angiotensin System

2009
CYP2C9 genotype modifies activity of the renin-angiotensin-aldosterone system in hypertensive men.
    Journal of hypertension, 2009, Volume: 27, Issue:10

    Topics: Adult; Aldosterone; Amlodipine; Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Bisoprolol; Cross-Over Studies; Cytochrome P-450 CYP2C9; Double-Blind Method; Drug Resistance; Electrolytes; Gene Frequency; Genotype; Humans; Hypertension, Renal; Losartan; Male; Middle Aged; Placebos; Renin; Renin-Angiotensin System

2009
Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment.
    International heart journal, 2009, Volume: 50, Issue:5

    Topics: Aged; Amlodipine; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Nifedipine; Tetrazoles

2009
Efficacy and tolerability of a fixed-dose combination of metoprolol extended release/amlodipine in patients with mild-to-moderate hypertension: a randomized, parallel-group, multicentre comparison with losartan plus amlodipine.
    Clinical drug investigation, 2010, Volume: 30, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Electrolytes; Female; Heart Rate; Humans; Losartan; Male; Metoprolol; Middle Aged; Young Adult

2010
Randomized, double-blind, controlled study of losartan in children with proteinuria.
    Clinical journal of the American Society of Nephrology : CJASN, 2010, Volume: 5, Issue:3

    Topics: Adolescent; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Child; Child, Preschool; Creatinine; Double-Blind Method; Europe; Female; Humans; Hypertension; Infant; Losartan; Male; Proteinuria; Time Factors; Treatment Outcome; United States

2010
Valsartan addition to amlodipine is more effective than losartan addition in hypertensive patients inadequately controlled by amlodipine.
    Vascular health and risk management, 2010, Mar-03, Volume: 6

    Topics: Adult; Aged; Amlodipine; Anthracenes; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan

2010
Blood pressure and medication during long-term antihypertensive therapy based on morning home SBP in hypertensive patients: Hypertension Control Based on Home Systolic Pressure (HOSP) substudy.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2010, Volume: 32, Issue:4

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Feasibility Studies; Female; Humans; Hypertension; Japan; Losartan; Male; Middle Aged; Pilot Projects; Time Factors; Treatment Outcome

2010
Role of plasma aldosterone concentration in regression of left-ventricular mass following antihypertensive medication.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: Adult; Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Ventricular Dysfunction, Left

2011
Calcium channel blocker and Rho-associated kinase activity in patients with hypertension.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Case-Control Studies; Cross-Sectional Studies; Double-Blind Method; Female; Humans; Hypertension; Leukocytes; Losartan; Male; Middle Aged; rho-Associated Kinases

2011
The effect of losartan and amlodipine on left ventricular diastolic function and atherosclerosis in Japanese patients with mild-to-moderate hypertension (J-ELAN) study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Asian People; Atherosclerosis; Calcium Channel Blockers; Carotid Arteries; Diabetes Mellitus; Diuretics; Drug Therapy, Combination; Dyslipidemias; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Platelet Aggregation Inhibitors; Treatment Outcome; Ventricular Function, Left

2011
Efficacy and safety of losartan in children with Alport syndrome--results from a subgroup analysis of a prospective, randomized, placebo- or amlodipine-controlled trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Child; Child, Preschool; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Infant; Losartan; Male; Nephritis, Hereditary; Prognosis; Prospective Studies; Proteinuria; Survival Rate; Treatment Outcome; Young Adult

2011
Losartan and amlodipine on myocardial structure and function: a prospective, randomized, clinical trial.
    Diabetic medicine : a journal of the British Diabetic Association, 2012, Volume: 29, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diastole; Echocardiography; Female; Fibrosis; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Myocardium; Prospective Studies; Treatment Outcome; Ventricular Dysfunction, Left

2012
Combination angiotensin-receptor blocker (ARB)/calcium channel blocker with HCTZ vs the maximal recommended dose of an ARB with HCTZ in patients with stage 2 hypertension: the exforge as compared to losartan treatment in stage 2 systolic hypertension (EXA
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:8

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; United States; Valine; Valsartan

2011
Plasma fibrin clot properties in arterial hypertension and their modification by antihypertensive medication.
    Thrombosis research, 2012, Volume: 130, Issue:1

    Topics: Adult; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Coagulation; Female; Fibrin; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Quinapril; Tetrahydroisoquinolines

2012
Effects of losartan and amlodipine alone or combined with simvastatin in hypertensive patients with nonalcoholic hepatic steatosis.
    European journal of gastroenterology & hepatology, 2012, Volume: 24, Issue:2

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Body Weight; Double-Blind Method; Drug Therapy, Combination; Fatty Liver; Female; Glucose Clamp Technique; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Inflammation Mediators; Insulin Resistance; Lipids; Losartan; Male; Middle Aged; Simvastatin; Ultrasonography

2012
Comparative efficacy and safety profile of amlodipine 5 mg/losartan 50 mg fixed-dose combination and amlodipine 10 mg monotherapy in hypertensive patients who respond poorly to amlodipine 5 mg monotherapy: an 8-week, multicenter, randomized, double-blind
    Clinical therapeutics, 2011, Volume: 33, Issue:12

    Topics: Adult; Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Republic of Korea; Time Factors; Treatment Outcome

2011
Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZ.
    Vascular health and risk management, 2011, Volume: 7

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2011
Evaluation of the dose-response relationship of amlodipine and losartan combination in patients with essential hypertension: an 8-week, randomized, double-blind, factorial, phase II, multicenter study.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2012, Feb-01, Volume: 12, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged

2012
Comparison of the efficacy and safety of fixed-dose amlodipine/losartan and losartan in hypertensive patients inadequately controlled with losartan: a randomized, double-blind, multicenter study.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2012, Jun-01, Volume: 12, Issue:3

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Republic of Korea; Time Factors; Treatment Outcome

2012
Change in high-sensitive cardiac troponin T on hypertensive treatment.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:1

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Troponin T

2013
Randomized Polypill crossover trial in people aged 50 and over.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Aged; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Losartan; Male; Middle Aged; Placebos; Simvastatin

2012
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
    Blood pressure, 2013, Volume: 22 Suppl 1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan

2013
Low-grade inflammation and ambulatory blood pressure response to antihypertensive treatment: the ALPHABET study.
    American journal of hypertension, 2013, Volume: 26, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Inflammation; Losartan; Male; Middle Aged; Treatment Outcome

2013
Efficacy and effects on lipid metabolism of combination treatment with losartan + hydrochlorothiazide versus losartan + amlodipine: a 48-week prospective, multicenter, randomized, open-label trial.
    Clinical therapeutics, 2013, Volume: 35, Issue:4

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Lipid Metabolism; Losartan; Male; Middle Aged; Prospective Studies

2013
Optimal medical treatment versus carotid endarterectomy: the rationale and design of the Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis (AMTEC) study.
    International journal of stroke : official journal of the International Stroke Society, 2015, Volume: 10, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Aspirin; Carotid Stenosis; Combined Modality Therapy; Endarterectomy, Carotid; Fibrinolytic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Myocardial Infarction; Prospective Studies; Research Design; Russia; Stroke

2015
Combination of antihypertensive therapy in the elderly, multicenter investigation (CAMUI) trial: results after 1 year.
    Journal of hypertension, 2013, Volume: 31, Issue:6

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Cognition; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male

2013
Control of home blood pressure with an amlodipine- or losartan-based regimen and progression of carotid artery intima-media thickness in hypertensive patients: the HOSP substudy.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:4

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Carotid Intima-Media Thickness; Circadian Rhythm; Disease Progression; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Pilot Projects

2013
Anti-hypertensive strategies in patients with MEtabolic parameters, DIabetes mellitus and/or NephropAthy (the M E D I N A study).
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2014, Volume: 158, Issue:3

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Diseases; Losartan; Male; Metabolic Syndrome; Middle Aged; Risk Factors; Single-Blind Method

2014
Echocardiographic changes and treatment goal rates after a 6-month combined treatment with amlodipine and losartan: a validation study in Andean countries (METAL study).
    Therapeutic advances in cardiovascular disease, 2013, Volume: 7, Issue:5

    Topics: Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Echocardiography; Female; Follow-Up Studies; Humans; Hypertension; Hyperuricemia; Losartan; Male; Middle Aged; South America; Time Factors; Treatment Outcome

2013
Comparative effectiveness of a fixed-dose combination of losartan + HCTZ versus bisoprolol + HCTZ in patients with moderate-to-severe hypertension: results of the 6-month ELIZA trial.
    Vascular health and risk management, 2013, Volume: 9

    Topics: Adrenergic beta-1 Receptor Antagonists; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chi-Square Distribution; Diuretics; Doxazosin; Drug Combinations; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Pulse Wave Analysis; Severity of Illness Index; Time Factors; Treatment Outcome; Ukraine; Vascular Stiffness

2013
Comparison of the effects of amlodipine and losartan on blood pressure and diurnal variation in hypertensive stroke patients: a prospective, randomized, double-blind, comparative parallel study.
    Clinical therapeutics, 2013, Volume: 35, Issue:12

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Stroke; Treatment Outcome

2013
[Possibilities of rational combination antihypertensive therapy: results of HEMERA international clinical trial].
    Terapevticheskii arkhiv, 2013, Volume: 85, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Ramipril; Treatment Outcome; Young Adult

2013
Functional vascular study in hypertensive subjects with type 2 diabetes using losartan or amlodipine.
    Arquivos brasileiros de cardiologia, 2014, Volume: 103, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Losartan; Male; Manometry; Middle Aged; Pulse Wave Analysis

2014
Efficacy and tolerability of amlodipine camsylate/losartan 5/100-mg versus losartan/hydrochlorothiazide 100/12.5-mg fixed-dose combination in hypertensive patients nonresponsive to losartan 100-mg monotherapy.
    Clinical therapeutics, 2014, Oct-01, Volume: 36, Issue:10

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome

2014
Efficacy and safety of fixed-dose losartan/hydrochlorothiazide/amlodipine combination versus losartan/hydrochlorothiazide combination in Japanese patients with essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Monitoring; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Treatment Outcome

2015
Fixed-dose combination of losartan and hydrochlorothiazide significantly improves endothelial function in uncontrolled hypertension by low-dose amlodipine: a randomized study.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2014, Volume: 14, Issue:8

    Topics: Aged; Amlodipine; Antihypertensive Agents; Brachial Artery; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Pulsatile Flow; Treatment Outcome

2014
Losartan reduces insulin resistance by inhibiting oxidative stress and enhancing insulin signaling transduction.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2015, Volume: 123, Issue:3

    Topics: 3T3-L1 Cells; Adipocytes; Aged; Amlodipine; Animals; Antihypertensive Agents; Diabetic Nephropathies; Humans; Insulin Resistance; Losartan; Male; Mice; Middle Aged; Oxidative Stress; Receptor, Insulin; Signal Transduction

2015
Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.
    Journal of the American Heart Association, 2015, Jan-26, Volume: 4, Issue:1

    Topics: Adult; Aldehyde Oxidoreductases; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Blood Pressure Monitoring, Ambulatory; Chloride Channels; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Essential Hypertension; Finland; Genome-Wide Association Study; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Membrane Proteins; Meta-Analysis as Topic; Microfilament Proteins; Middle Aged; Mutation, Missense; Pharmacogenetics; Polymorphism, Single Nucleotide; Severity of Illness Index; Tetrazoles; Treatment Outcome

2015
Prospective randomized study of the tolerability and efficacy of combination therapy for hypertensive chronic kidney disease: results of the PROTECT-CKD study.
    Clinical and experimental nephrology, 2015, Volume: 19, Issue:5

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension, Renal; Losartan; Male; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Young Adult

2015
[Effectiveness and safety of losartan and its combination with amlodipine in therapy of arterial hypertension].
    Klinicheskaia meditsina, 2013, Volume: 91, Issue:12

    Topics: Aged; Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome

2013
Add-on effect of hydrochlorothiazide 12.5 mg in Japanese subjects with essential hypertension uncontrolled with losartan 50 mg and amlodipine 5 mg.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Single-Blind Method; Treatment Outcome; Young Adult

2015
Visit-to-visit variability and seasonal variation in blood pressure: Combination of Antihypertensive Therapy in the Elderly, Multicenter Investigation (CAMUI) Trial subanalysis.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Prospective Studies; Seasons; Treatment Outcome

2015
Renin-Angiotensin System Blockade Associated with Statin Improves Endothelial Function in Diabetics.
    Arquivos brasileiros de cardiologia, 2015, Volume: 105, Issue:6

    Topics: Amino Acids; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Pulse Wave Analysis; Renin-Angiotensin System; Statistics, Nonparametric; Time Factors; Treatment Outcome; Vascular Stiffness

2015
Effect of Diuretic or Calcium-Channel Blocker Plus Angiotensin-Receptor Blocker on Diastolic Function in Hypertensive Patients.
    Circulation journal : official journal of the Japanese Circulation Society, 2016, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Diastole; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Ventricular Dysfunction, Left

2016
Effect of losartan combined with amlodipine or with a thiazide on uric acid levels in hypertensive patients.
    Therapeutic advances in cardiovascular disease, 2017, Volume: 11, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Biomarkers; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Time Factors; Treatment Outcome; Uric Acid

2017
The effects of missed doses of amlodipine and losartan on blood pressure in older hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2017, Volume: 40, Issue:6

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Treatment Outcome

2017
Comparison of Fixed-dose Combinations of Amlodipine/Losartan Potassium/Chlorthalidone and Amlodipine/Losartan Potassium in Patients With Stage 2 Hypertension Inadequately Controlled With Amlodipine/Losartan Potassium: A Randomized, Double-blind, Multicent
    Clinical therapeutics, 2017, Volume: 39, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Young Adult

2017
A Randomized, Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and the Tolerability of a Triple Combination of Amlodipine/Losartan/Rosuvastatin in Patients With Comorbid Essential Hypertension and Hyperlipidemia.
    Clinical therapeutics, 2017, Volume: 39, Issue:12

    Topics: Aged; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Blood Pressure; Comorbidity; Double-Blind Method; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypercholesterolemia; Losartan; Male; Middle Aged; Risk Factors; Rosuvastatin Calcium; Treatment Outcome

2017
Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial.
    Journal of the American Heart Association, 2017, Nov-18, Volume: 6, Issue:11

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Young Adult

2017
Comparison of 24-Hour Ambulatory Central Blood Pressure Reduction Efficacy Between Fixed Amlodipine or Up-Titrated Hydrochlorothiazide Plus Losartan: The K-Central Study.
    American journal of hypertension, 2019, 09-24, Volume: 32, Issue:10

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Republic of Korea; Time Factors; Treatment Outcome

2019
The association of smoothness index of central blood pressure with ambulatory carotid femoral pulse wave velocity after 20-week treatment with losartan in combination with amlodipine versus hydrochlorothiazide.
    Journal of hypertension, 2019, Volume: 37, Issue:12

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Carotid-Femoral Pulse Wave Velocity; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged

2019
Polypill for Cardiovascular Disease Prevention in an Underserved Population.
    The New England journal of medicine, 2019, 09-19, Volume: 381, Issue:12

    Topics: Adult; Alabama; Amlodipine; Antihypertensive Agents; Atorvastatin; Cholesterol, LDL; Community Health Centers; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Losartan; Male; Medically Underserved Area; Medication Adherence; Middle Aged

2019
Comparison of Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan/Rosuvastatin with Concomitant Administration of Amlodipine/Losartan and Rosuvastatin in Healthy Volunteers.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Administration, Oral; Adult; Amlodipine; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Drug Compounding; Healthy Volunteers; Humans; Losartan; Male; Middle Aged; Rosuvastatin Calcium; Tablets

2020
Comparison of Blood Pressure Variability Between Losartan and Amlodipine in Essential Hypertension (COMPAS-BPV).
    American journal of hypertension, 2020, 08-04, Volume: 33, Issue:8

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Losartan; Male; Middle Aged

2020
Low-Dose Triple Antihypertensive Combination Therapy in Patients with Hypertension: A Randomized, Double-Blind, Phase II Study.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged

2020
Comparison of losartan and amlodipine effects on the outcomes of patient with COVID-19 and primary hypertension: A randomised clinical trial.
    International journal of clinical practice, 2021, Volume: 75, Issue:6

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; COVID-19; Double-Blind Method; Humans; Hypertension; Losartan; Middle Aged; SARS-CoV-2; Treatment Outcome

2021
Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan and Chlorthalidone Compared to Concurrent Administration of the Separate Components.
    Clinical pharmacology in drug development, 2022, Volume: 11, Issue:1

    Topics: Amlodipine; Chlorthalidone; Cross-Over Studies; Drug Combinations; Humans; Losartan

2022
The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial.
    European stroke journal, 2023, Volume: 8, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Cross-Over Studies; Humans; Losartan; Prospective Studies; Randomized Controlled Trials as Topic

2023
Comparison of efficacy and safety between third-dose triple and third-dose dual antihypertensive combination therapies in patients with hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Hypotension; Losartan; Treatment Outcome

2023
A Randomized, Multicenter, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a Quadruple Combination of Amlodipine, Losartan, Rosuvastatin, and Ezetimibe in Patients with Concomitant Essential Hypertension and Dyslipidemia.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2023, Volume: 23, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cholesterol, LDL; Double-Blind Method; Dyslipidemias; Essential Hypertension; Ezetimibe; Humans; Hypertension; Losartan; Rosuvastatin Calcium; Treatment Outcome

2023

Other Studies

67 other study(ies) available for amlodipine and losartan

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Protection of the arterial internal elastic lamina by inhibition of the renin-angiotensin system in the rat.
    Circulation research, 1998, May-04, Volume: 82, Issue:8

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Rupture; Benzimidazoles; Blood Pressure; Body Weight; Calcium Channel Blockers; Collagen; Elastic Tissue; Elastin; Enalapril; Heart; Heart Rate; Losartan; Male; Mibefradil; Muscle, Smooth, Vascular; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred BN; Renin; Renin-Angiotensin System; Tetrahydronaphthalenes

1998
Randomized clinical trials of antihypertensive drugs: all that glitters is not gold.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1998, Sep-08, Volume: 159, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Bias; Canada; Evidence-Based Medicine; Humans; Losartan; Randomized Controlled Trials as Topic; Reproducibility of Results; Research Design; Treatment Outcome

1998
Key features of candesartan cilexetil and a comparison with other angiotensin II receptor antagonists.
    Journal of human hypertension, 1999, Volume: 13 Suppl 1

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Delayed-Action Preparations; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Losartan; Renin-Angiotensin System; Retrospective Studies; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome

1999
[Arterial hypertension and systolic left ventricular dysfunction: therapeutic approach].
    Revista espanola de cardiologia, 1999, Volume: 52 Suppl 3

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Carbazoles; Carvedilol; Clinical Trials as Topic; Databases, Bibliographic; Felodipine; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Meta-Analysis as Topic; Propanolamines; Randomized Controlled Trials as Topic; Risk Factors; Systole; Vasodilator Agents; Ventricular Dysfunction, Left

1999
Diverse effects of chronic treatment with losartan, fosinopril, and amlodipine on apoptosis, angiotensin II in the left ventricle of hypertensive rats.
    International journal of cardiology, 2001, Volume: 81, Issue:2-3

    Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; China; Disease Models, Animal; Fosinopril; Heart Ventricles; Hypertrophy, Left Ventricular; Losartan; Models, Cardiovascular; Myocardium; Random Allocation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1

2001
[Comparative effects of losartan and amlodipine on activities of sympathetic nerve, renin-angiotensin-aldosterone system and brain natriuretic peptide in the elderly hypertensive patients].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2002, Volume: 39, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Heart Rate; Humans; Hypertension; Losartan; Natriuretic Peptide, Brain; Renin-Angiotensin System; Sympathetic Nervous System

2002
Targeting the atherosclerotic process in clinical practice. A new look at established agents.
    Atherosclerosis, 2002, Volume: 165, Issue:2

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Risk Factors

2002
Differential effects of antihypertensive drug therapy on arterial compliance.
    American journal of hypertension, 2002, Volume: 15, Issue:12

    Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium Channel Blockers; Enalapril; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Vascular Resistance

2002
[Contrast of losartan, fosinopril and amlodipine on cardiomyocyte apoptosis and left ventricular remolding in hypertensive rats].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2001, Oct-28, Volume: 26, Issue:5

    Topics: Amlodipine; Animals; Antihypertensive Agents; Apoptosis; Cardiotonic Agents; Female; Fosinopril; Hypertension; Losartan; Male; Myocytes, Cardiac; Random Allocation; Rats; Rats, Inbred SHR; Ventricular Remodeling

2001
Anti-proteinuric effect of losartan: statistical vs clinical significance.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Data Interpretation, Statistical; Humans; Losartan; Proteinuria; Treatment Outcome

2004
Doxorubicine-congestive heart failure-increased big endothelin-1 plasma concentration: reversal by amlodipine, losartan, and gastric pentadecapeptide BPC157 in rat and mouse.
    Journal of pharmacological sciences, 2004, Volume: 95, Issue:1

    Topics: Amlodipine; Animals; Doxorubicin; Endothelin-1; Gastric Mucosa; Heart Failure; Losartan; Male; Mice; Peptide Fragments; Peptides; Proteins; Rats; Rats, Wistar; Stomach

2004
Valsartan treatment of hypertension--does VALUE add value?
    Lancet (London, England), 2004, Jun-19, Volume: 363, Issue:9426

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Endpoint Determination; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan

2004
Evaluation of a technique of inducing hypertensive renal insufficiency in cats.
    American journal of veterinary research, 2004, Volume: 65, Issue:7

    Topics: Amlodipine; Analysis of Variance; Animals; Blood Pressure; Blood Pressure Determination; Cat Diseases; Cats; Diltiazem; Enalapril; Heart Rate; Hypertension, Renal; Infarction; Kidney; Ligation; Losartan; Nephrectomy; Renal Insufficiency; Telemetry; Time Factors

2004
[Characteristics of hypotensive effect in patients with arterial hypertension and desaturation signs of obstructive sleep apnea syndrome during sleep].
    Terapevticheskii arkhiv, 2004, Volume: 76, Issue:6

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Sleep; Sleep Apnea, Obstructive; Treatment Outcome

2004
Adult hypertension: reducing cardiovascular morbidity and mortality.
    Prescrire international, 2005, Volume: 14, Issue:75

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complications; Diltiazem; Diuretics; Drug Evaluation; Health Behavior; Humans; Hypertension; Losartan; Obesity; Renal Insufficiency; Sodium; Stroke; Verapamil

2005
TGF-beta and TNF-alpha producing effects of losartan and amlodipine on human mononuclear cell culture.
    Nephrology (Carlton, Vic.), 2005, Volume: 10, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Atherosclerosis; Cells, Cultured; Humans; Leukocytes, Mononuclear; Losartan; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2005
[Pharmacogenetics of angiotensin system in non diabetic nephropathy].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2005, Volume: 25, Issue:4

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Chronic Disease; Data Interpretation, Statistical; Female; Genotype; Glomerulonephritis; Humans; Kidney Diseases; Losartan; Male; Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Proteinuria

2005
Renal mitochondrial dysfunction in spontaneously hypertensive rats is attenuated by losartan but not by amlodipine.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 290, Issue:6

    Topics: Actins; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Calcium Channel Blockers; Electron Transport Complex IV; Glomerular Mesangium; Glutathione; Hydrogen Peroxide; Hypertension; Ion Channels; Kidney; Losartan; Male; Membrane Potentials; Membrane Transport Proteins; Mitochondria; Mitochondrial Proteins; NADH Dehydrogenase; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxide Dismutase; Uncoupling Protein 2

2006
Arteriolar remodeling in essential hypertension: are connective tissue growth factor and transforming growth factor involved?
    Kidney international, 2006, Volume: 69, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Arterioles; Connective Tissue Growth Factor; Humans; Hypertension; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Losartan; Transforming Growth Factor beta

2006
Antihypertensive agents have different ability to modulate arterial pressure and heart rate variability in 2K1C rats.
    American journal of hypertension, 2006, Volume: 19, Issue:10

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Autonomic Nervous System; Blood Pressure; Cardiovascular System; Heart Rate; Hydrochlorothiazide; Hypertension; Losartan; Male; Ramipril; Rats; Rats, Wistar; Sympathetic Nervous System

2006
Pulsology reloaded: commentary on similar effects of treatment on central and brachial blood pressure in older hypertensive subjects.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Brachial Artery; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Losartan; Manometry; Perindopril; Ultrasonography, Doppler

2007
Sudden cardiac standstill during skin flap elevation in a patient undergoing craniotomy.
    Journal of neurosurgical anesthesiology, 2007, Volume: 19, Issue:3

    Topics: Aged; Amlodipine; Anesthesia, General; Anti-Arrhythmia Agents; Antihypertensive Agents; Atropine; Blood Pressure; Bradycardia; Brain Neoplasms; Calcium Channel Blockers; Craniotomy; Dermatologic Surgical Procedures; Female; Heart Arrest; Heart Rate; Humans; Hypertension; Losartan; Reflex, Abnormal; Skin; Surgical Flaps; Trigeminal Nerve

2007
Renal mitochondrial impairment is attenuated by AT1 blockade in experimental Type I diabetes.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Electron Transport Complex IV; Glutathione; Hydrogen Peroxide; Ion Channels; Kidney; Losartan; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Proteins; Nitric Oxide Synthase; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Uncoupling Protein 2

2008
Application in the STRATHE trial of a score system to compare the efficacy and the tolerability of different therapeutic strategies in the management of hypertension.
    Vascular health and risk management, 2008, Volume: 4, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Atenolol; Double-Blind Method; Drug Therapy, Combination; France; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Losartan; Perindopril; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan

2008
Beneficial effects of the combination of amlodipine and losartan for lowering blood pressure in spontaneously hypertensive rats.
    Archives of pharmacal research, 2009, Volume: 32, Issue:3

    Topics: Acetylcholine; Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Calcium Channel Blockers; Cardiomegaly; Collagen; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Losartan; Myocardium; Rats; Rats, Inbred SHR; Time Factors; Vasodilation; Vasodilator Agents

2009
Simultaneous spectrophotometric determination of losartan potassium, amlodipine besilate and hydrochlorothiazide in pharmaceuticals by chemometric methods.
    Acta pharmaceutica (Zagreb, Croatia), 2010, Volume: 60, Issue:2

    Topics: Amlodipine; Chemistry, Pharmaceutical; Hydrochlorothiazide; Least-Squares Analysis; Linear Models; Losartan; Multivariate Analysis; Principal Component Analysis; Spectrophotometry, Ultraviolet; Tablets

2010
Anti-inflammatory effects of anti-hypertensive agents: influence on interleukin-1β secretion by peripheral blood polymorphonuclear leukocytes from patients with essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2011, Volume: 33, Issue:2

    Topics: Adult; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Atenolol; Captopril; Case-Control Studies; Female; Humans; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Losartan; Male; Middle Aged; Neutrophils

2011
Scintigraphic diagnosis of Erdheim-Chester disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-01, Volume: 29, Issue:16

    Topics: Aged; Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Combinations; Erdheim-Chester Disease; Gated Blood-Pool Imaging; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Hypolipidemic Agents; Imidazoles; Knee Joint; Losartan; Male; Metformin; Positron-Emission Tomography; Prostatic Neoplasms; Simvastatin

2011
Tube feeding and drugs in intensive care unit.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Critical Care; Delayed-Action Preparations; Drug Combinations; Drug Delivery Systems; Drug-Related Side Effects and Adverse Reactions; Enteral Nutrition; Female; Humans; Intensive Care Units; Intubation, Gastrointestinal; Losartan; Pharmaceutical Preparations

2011
STK39 variation predicts the ambulatory blood pressure response to losartan in hypertensive men.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:1

    Topics: Adult; Alleles; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Genotype; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases

2012
An economic evaluation of antihypertensive therapies based on clinical trials.
    Clinics (Sao Paulo, Brazil), 2012, Volume: 67, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Drug Costs; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Randomized Controlled Trials as Topic

2012
Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice.
    Kidney international, 2012, Volume: 82, Issue:1

    Topics: Aldosterone; Amiloride; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Weight; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Homeostasis; Hypertension; Kidney; Losartan; Male; Mice; Mice, Knockout; Natriuresis; Renin; Serine Endopeptidases; Sodium Channel Blockers; Sodium Chloride, Dietary; Telemetry; Time Factors

2012
Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of losartan and amlodipine regarding long-term blood pressure, cardiac and renal protection.
    International journal of molecular medicine, 2012, Volume: 30, Issue:6

    Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Collagen; Gene Expression Regulation; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Kidney; Losartan; Male; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stroke Volume; Transforming Growth Factor beta1; Ultrasonography

2012
Differential effects of antihypertensive treatments on apoptosis, oxidative stress, and expression of angiotensin receptors in the cerebral cortex from the onset of prehypertension and hypertension in stroke-prone spontaneous hypertensive rats.
    Neuroreport, 2013, Nov-13, Volume: 24, Issue:16

    Topics: Amlodipine; Animals; Antihypertensive Agents; Apoptosis; Blotting, Western; Cerebral Cortex; Hypertension; Losartan; Male; Oxidative Stress; Prehypertension; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin

2013
The influence of food on the pharmacokinetics of amlodipine and losartan after single-dose of its compound tablets in healthy chinese subjects.
    Drug research, 2014, Volume: 64, Issue:5

    Topics: Administration, Oral; Adult; Amlodipine; Area Under Curve; Asian People; Female; Food; Food-Drug Interactions; Humans; Imidazoles; Losartan; Male; Tablets; Tetrazoles; Young Adult

2014
Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats.
    International journal of molecular medicine, 2014, Volume: 33, Issue:2

    Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Apoptosis; Blood Pressure; Brain; Hypertension; Losartan; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Prehypertension; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Stroke; Superoxide Dismutase; Time Factors

2014
Prehypertensive treatment with losartan, however not amlodipine, leads to long-term effects on blood pressure and reduces the risk of stroke in spontaneously hypertensive stroke-prone rats.
    Molecular medicine reports, 2016, Volume: 13, Issue:2

    Topics: Amlodipine; Animals; Blood Pressure; Gene Expression Regulation; Humans; Hypertension; Losartan; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Risk Factors; Stroke

2016
Cost-benefit analysis of the polypill in the primary prevention of myocardial infarction and stroke.
    European journal of epidemiology, 2016, Volume: 31, Issue:4

    Topics: Aged; Aged, 80 and over; Amlodipine; Aspirin; Cardiovascular Agents; Case-Control Studies; Cohort Studies; Cost-Benefit Analysis; Humans; Hydrochlorothiazide; Losartan; Markov Chains; Middle Aged; Myocardial Infarction; Polypharmacy; Primary Prevention; Quality-Adjusted Life Years; Simvastatin; Stroke; United Kingdom

2016
Losartan and amlodipine overdose-Case Report of a patient with anuric renal failure prior to the onset of hypotension.
    The New Zealand medical journal, 2016, May-27, Volume: 129, Issue:1435

    Topics: Acute Kidney Injury; Amlodipine; Antihypertensive Agents; Anuria; Drug Overdose; Female; Humans; Hypotension; Losartan; Middle Aged

2016
Prediction of drug interaction between oral adsorbent AST-120 and concomitant drugs based on the in vitro dissolution and in vivo absorption behavior of the drugs.
    European journal of clinical pharmacology, 2016, Volume: 72, Issue:11

    Topics: Administration, Oral; Adsorption; Aluminum Hydroxide; Amlodipine; Aspirin; Carbon; Drug Interactions; Glycine; Humans; Intestinal Absorption; Losartan; Magnesium; Metoprolol; Models, Biological; Nifedipine; Oxides; Renal Insufficiency, Chronic; Solubility; Triazolam

2016
Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Half-Life; Healthy Volunteers; Humans; Losartan

2016
Molecular insight into atypical instability behavior of fixed-dose combination containing amlodipine besylate and losartan potassium.
    Journal of pharmaceutical and biomedical analysis, 2017, Mar-20, Volume: 136

    Topics: Amlodipine; Chromatography, High Pressure Liquid; Drug Combinations; Drug Compounding; Drug Interactions; Drug Stability; Hydrogen-Ion Concentration; Losartan; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure

2017
Cost-effectiveness of the polypill versus risk assessment for prevention of cardiovascular disease.
    Heart (British Cardiac Society), 2017, Volume: 103, Issue:7

    Topics: Administration, Oral; Adult; Aged; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Computer Simulation; Cost-Benefit Analysis; Drug Combinations; Drug Costs; Dyslipidemias; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Losartan; Male; Middle Aged; Models, Economic; Primary Prevention; Quality-Adjusted Life Years; Risk Assessment; Risk Factors; Simvastatin; Tablets; Time Factors; Treatment Outcome

2017
Inhibition of the Renin-Angiotensin System Post Myocardial Infarction Prevents Inflammation-Associated Acute Cardiac Rupture.
    Cardiovascular drugs and therapy, 2017, Volume: 31, Issue:2

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemotaxis, Leukocyte; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rupture, Post-Infarction; Inflammation; Inflammation Mediators; Losartan; Male; Mice, 129 Strain; Monocytes; Myocardial Infarction; Myocardium; Neutrophil Infiltration; Neutrophils; Perindopril; Renin-Angiotensin System; Spleen; Time Factors

2017
[The Effectiveness of Combination Antihypertensive Therapy in Women With Hypothyroidism and the Metabolic Syndrome].
    Kardiologiia, 2016, Volume: 56, Issue:9

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Hypothyroidism; Imidazoles; Losartan; Metabolic Syndrome; Middle Aged

2016
Influence of antihypertensive drugs on aortic and coronary effects of Ang-(1-7) in pressure-overloaded rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, Mar-23, Volume: 50, Issue:4

    Topics: Amlodipine; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Calcium Channel Blockers; Captopril; Coronary Vessels; Losartan; Male; Mineralocorticoid Receptor Antagonists; Models, Animal; Peptide Fragments; Rats, Wistar; Reproducibility of Results; Spironolactone; Time Factors; Vasoconstriction; Vasodilation

2017
Endothelial transcriptomics reveals activation of fibrosis-related pathways in hypertension.
    Physiological genomics, 2018, 02-01, Volume: 50, Issue:2

    Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Fibrosis; Heart Rate; Hypertension; Losartan; Male; Mice

2018
Alternatives to specific uric acid lowering treatment in gout in patients with cardiovascular disease.
    BMJ (Clinical research ed.), 2018, Sep-20, Volume: 362

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atorvastatin; Calcium Channel Blockers; Cardiovascular Diseases; Clopidogrel; Gout; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Purinergic P2Y Receptor Antagonists; Risk Factors; Uric Acid

2018
Effects of Different Antihypertensive Drug Combinations on Blood Pressure and Arterial Stiffness.
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2019, Volume: 73, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Arteries; Blood Pressure; Diastole; Drug Combinations; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Lisinopril; Losartan; Male; Middle Aged; Prospective Studies; Pulse Wave Analysis; Systole; Valsartan; Vascular Resistance; Vascular Stiffness

2019
The smoothness index: an 'all purposes' approach to the assessment of the homogeneity of 24-h blood pressure control?
    Journal of hypertension, 2019, Volume: 37, Issue:12

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Hydrochlorothiazide; Losartan; Pulse Wave Analysis

2019
Detection of significant left renal artery stenosis caused by fibromuscular dysplasia with selective angiography.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2020, Jan-14, Volume: 91, Issue:4

    Topics: Amlodipine; Angioplasty, Balloon; Antihypertensive Agents; Computed Tomography Angiography; Drug Combinations; Female; Fibromuscular Dysplasia; Headache; Humans; Hypertension; Losartan; Renal Artery Obstruction; Young Adult

2020
Oral Manifestations of Commonly Prescribed Drugs.
    American family physician, 2020, 11-15, Volume: 102, Issue:10

    Topics: Albuterol; Amlodipine; Anticonvulsants; Antihypertensive Agents; Atorvastatin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bronchodilator Agents; Deprescriptions; Drug Hypersensitivity; Fluorides; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperpigmentation; Hypoglycemic Agents; Lisinopril; Losartan; Metformin; Metoprolol; Mouth Diseases; Omeprazole; Oral Hygiene; Proton Pump Inhibitors; Simvastatin; Thyroxine; Toothpastes; Xerostomia

2020
More Than Meets the Eye: A Patient with Hand Swelling and Newly Diagnosed Diabetes Mellitus.
    The American journal of medicine, 2021, Volume: 134, Issue:11

    Topics: Aged; Amlodipine; Anemia; Antihypertensive Agents; Blood Sedimentation; C-Reactive Protein; Diabetes Mellitus, Type 2; Edema; Glucocorticoids; Hand; Humans; Hypertension; Hypoglycemic Agents; Losartan; Male; Metformin; Prednisolone; Rotator Cuff Injuries; Syndrome; Synovitis

2021
Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease.
    The Journal of clinical investigation, 2021, 09-15, Volume: 131, Issue:18

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cerebral Small Vessel Diseases; Cerebrovascular Circulation; Dementia, Vascular; Disease Models, Animal; Drug Therapy, Combination; Eplerenone; Heart Disease Risk Factors; Humans; Hyperemia; Hypertension; Losartan; Male; Mice; Microvessels; Potassium Channels, Inwardly Rectifying; Renin-Angiotensin System

2021
Clinical effectiveness and safety of amlodipine/losartan-based single-pill combination therapy in patients with hypertension: Findings from real-world, multicenter observational databases.
    Journal of clinical hypertension (Greenwich, Conn.), 2021, Volume: 23, Issue:11

    Topics: Amlodipine; Antihypertensive Agents; Humans; Hypertension; Losartan; Treatment Outcome; Uric Acid

2021
Dose-dependent atorvastatin associated with angioedema.
    International journal of clinical pharmacology and therapeutics, 2022, Volume: 60, Issue:2

    Topics: Aged; Amlodipine; Angioedema; Antihypertensive Agents; Atorvastatin; Calcium Channel Blockers; Female; Humans; Hypertension; Losartan

2022
Comment on 'Comparison of losartan and amlodipine effects on the outcomes of patient with COVID-19 and primary hypertension: A randomised clinical trial'.
    International journal of clinical practice, 2021, Volume: 75, Issue:12

    Topics: Amlodipine; Antihypertensive Agents; COVID-19; Humans; Hypertension; Losartan; SARS-CoV-2

2021
Antihypertensive medicine use differs between Ghana and Nigeria.
    BMC cardiovascular disorders, 2022, 08-10, Volume: 22, Issue:1

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Ghana; Humans; Hypertension; Lisinopril; Losartan; Nifedipine; Nigeria

2022
IR microspectroscopic investigation of the interaction of some losartan salts with human stratum corneum protein and its effect on losartan transdermal permeation.
    PloS one, 2023, Volume: 18, Issue:6

    Topics: Amlodipine; Humans; Keratins; Leukemia, Myeloid, Acute; Losartan; Pharmaceutical Preparations; Salts; Skin

2023
NITROSOGENESIS OF SKIN CANCER: THE NITROSAMINE CONTAMINATION IN THE CALCIUM CHANNEL BLOCKERS (AMLODIPINE), BETA BLOCKERS (BISOPROLOL), SARTANS (VALSARTAN/LOSARTAN), ACE INHIBITORS (PERINDOPRIL/ENALAPRIL), TRICYCLIC ANTIDEPRESSANTS (MELITRACEN), SSRIS (PAR
    Georgian medical news, 2023, Issue:339

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Tricyclic; Bisoprolol; Calcium Channel Blockers; Enalapril; Humans; Incidence; Losartan; Metformin; Paroxetine; Perindopril; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Skin Neoplasms; Valsartan; Venlafaxine Hydrochloride

2023