amlodipine has been researched along with isradipine in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.94) | 18.7374 |
| 1990's | 17 (50.00) | 18.2507 |
| 2000's | 9 (26.47) | 29.6817 |
| 2010's | 7 (20.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Einzinger, U; Hoda, JC; Huber, IG; Koschak, A; Obermair, GJ; Sartori, SB; Sinnegger-Brauns, MJ; Striessnig, J; Wild, C | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Reimão, JQ; Scotti, MT; Tempone, AG | 1 |
| Sun, H | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Mason, RP; Moisey, DM; Shajenko, L | 1 |
| Gu, XH; Nayler, WG | 1 |
| Matlib, MA | 1 |
| Deguchi, Y; Kimura, R; Sugimoto, N; Uchida, S; Yamada, S | 1 |
| Godfraind, T; Morel, N | 1 |
| Hattori, K; Maruyama, K; Nagatomo, T; Qu, YL; Sugiyama, K; Takamizawa, C; Watanabe, K | 1 |
| Bangalore, R; Glossmann, H; Kass, RS; Kwan, YW; Lakitsh, M | 1 |
| De Keyser, P; Deblander, A; Hermans, L; Lesaffre, E; Scheys, I; Westelinck, KJ | 1 |
| Locher, R; Lupo, E; Vetter, W; Weisser, B | 1 |
| Fetkovska, N; Oravcova, J; Sojkova, D; Trnovec, T | 1 |
| Block, LH; Nauck, M; Rödler, S; Roth, M; Tamm, M | 1 |
| Gilar, M; Tesarová, E; Uhrová, M | 1 |
| Hattori, K; Maruyama, K; Nagatomo, T; Qu, YL; Sugiyama, K; Watanabe, K | 1 |
| Crouzel, C; Dollé, F; Duval, R; Fuseau, C; Hinnen, F; Péglion, JL; Valette, H | 1 |
| Furberg, CD; Pahor, M; Psaty, BM | 1 |
| Seibold, JR; Sturgill, MG | 1 |
| Burgess, SE; Cavallero, CA; Gardell, LR; Hubbell, CL; Reid, LD; Reid, ML; Wallace, RF | 1 |
| Antepohl, W; Haaf, O; Herzig, S; Huber, I; Matthes, J; Striessnig, J | 1 |
| Marche, P; Stepien, O | 1 |
| Faverdin, C; Marche, P; Polidano, E; Yin, X | 1 |
| Ganz, M; Mokabberi, R; Sica, DA | 1 |
| Beydemir, S; Söyüt, H; Türkeş, C | 1 |
2 review(s) available for amlodipine and isradipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
New drugs for hypertension--variations on old themes.
Topics: Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dihydropyridines; Doxazosin; Humans; Hypertension; Isradipine; Nifedipine; Prazosin; Verapamil | 1991 |
2 trial(s) available for amlodipine and isradipine
| Article | Year |
|---|---|
At equipotent doses, isradipine is better tolerated than amlodipine in patients with mild-to-moderate hypertension: a double-blind, randomized, parallel-group study.
Topics: Adult; Aged; Amlodipine; Ankle; Belgium; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Edema; Female; Humans; Hypertension; Isradipine; Male; Middle Aged; Nausea; Patient Compliance; Surveys and Questionnaires; Therapeutic Equivalency | 1994 |
Comparison of blood pressure control with amlodipine and controlled-release isradipine: an open-label, drug substitution study.
Topics: Amlodipine; Analysis of Variance; Blood Pressure Determination; Calcium Channel Blockers; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Isradipine; Male; Middle Aged; Probability; Risk Assessment; Severity of Illness Index; Single-Blind Method; Treatment Outcome | 2005 |
30 other study(ies) available for amlodipine and isradipine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms.
Topics: Amino Acid Motifs; Animals; Brain; Calcium Channels, L-Type; Dihydropyridines; Female; Gene Expression; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Protein Isoforms | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
(-)[3H]amlodipine binding to rat cardiac membranes.
Topics: Amlodipine; Animals; Female; Gallopamil; Hydrogen-Ion Concentration; In Vitro Techniques; Isradipine; Kinetics; Membranes; Myocardium; Nifedipine; Oxadiazoles; Rats; Rats, Inbred Strains; Stereoisomerism; Temperature | 1991 |
Relaxation of potassium chloride-induced contractions by amlodipine and its interaction with the 1,4-dihydropyridine-binding site in pig coronary artery.
Topics: Amlodipine; Animals; Binding Sites; Calcium Channel Blockers; Coronary Vessels; Dihydropyridines; Isradipine; Nifedipine; Oxadiazoles; Potassium Chloride; Sarcolemma; Stereoisomerism; Swine; Vasoconstriction; Vasodilation | 1989 |
Pharmacokinetics of amlodipine and its occupancy of calcium antagonist receptors.
Topics: Amlodipine; Animals; Brain; Calcium Channels; In Vitro Techniques; Isradipine; Kinetics; Male; Membranes; Myocardium; Rats; Rats, Inbred SHR | 1994 |
Selective interaction of the calcium antagonist amlodipine with calcium channels in arteries of spontaneously hypertensive rats.
Topics: Administration, Oral; Amlodipine; Animals; Aorta; Binding Sites; Blood Pressure; Calcium Channels; Calcium Channels, L-Type; Electrophysiology; Isradipine; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity | 1994 |
Residual inhibition in density of [3H]isradipine binding sites in rat brain membrane pretreated with amlodipine.
Topics: Amlodipine; Animals; Binding Sites; Brain; Calcium Channel Blockers; Dihydropyridines; Isradipine; Male; Nifedipine; Oxadiazoles; Radioligand Assay; Rats; Rats, Wistar | 1995 |
Inhibition of cardiac L-type calcium channels by quaternary amlodipine: implications for pharmacokinetics and access to dihydropyridine binding site.
Topics: Amlodipine; Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Guinea Pigs; Heart Ventricles; Humans; Isradipine; Kinetics; Membrane Potentials; Muscle, Skeletal; Myocardium; Rabbits | 1995 |
In vitro antioxidant activity of calcium antagonists against LDL oxidation compared with alpha-tocopherol.
Topics: Adult; Amlodipine; Antioxidants; Calcium Channel Blockers; Copper; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Humans; Isradipine; Lipoproteins, LDL; Oxidation-Reduction; Reference Values; Thiobarbituric Acid Reactive Substances; Verapamil; Vitamin E | 1994 |
Factors influencing isradipine and amlodipine binding to human plasma lipoproteins.
Topics: Amlodipine; Blood; Cyclosporine; Humans; Isradipine; Lipoproteins | 1994 |
Ca(2+)-channel blockers modulate the expression of interleukin-6 and interleukin-8 genes in human vascular smooth muscle cells.
Topics: Adrenergic beta-Antagonists; Amlodipine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Diuretics; Felodipine; Fibroblasts; Furosemide; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Isradipine; Lung; Muscle Proteins; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Propranolol; Transcription, Genetic | 1995 |
Enantiomer separation of dihydropyridine calcium antagonists with cyclodextrins as chiral selectors: structural correlation.
Topics: Amlodipine; Buffers; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cyclodextrins; Dihydropyridines; Electrolytes; Electrophoresis, Capillary; Isradipine; Microspheres; Molecular Conformation; Nimodipine; Nisoldipine; Nitrendipine; Sodium Dodecyl Sulfate; Solvents; Stereoisomerism; Surface-Active Agents | 1996 |
Slow dissociation of long-acting Ca2+ antagonist amlodipine from 3H-PN200-110 binding sites in membranes of rat hearts and brains.
Topics: Amlodipine; Animals; Binding Sites; Brain; Calcium Channel Blockers; Cell Membrane; Isradipine; Male; Myocardium; Rats; Rats, Wistar; Structure-Activity Relationship | 1996 |
Synthesis of two optically active calcium channel antagonists labelled with carbon-11 for in vivo cardiac PET imaging.
Topics: Amlodipine; Animals; Binding, Competitive; Calcium Channel Blockers; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dihydropyridines; Dogs; Heart; Heart Diseases; Isotope Labeling; Isradipine; Magnetic Resonance Spectroscopy; Muscle, Smooth, Vascular; Myocardium; Reproducibility of Results; Stereoisomerism; Tomography, Emission-Computed | 1997 |
Treatment of hypertensive patients with diabetes.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Case-Control Studies; Cohort Studies; Diabetes Complications; Enalapril; Fosinopril; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Nisoldipine; Randomized Controlled Trials as Topic | 1998 |
Rational use of calcium-channel antagonists in Raynaud's phenomenon.
Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Humans; Isradipine; Nicardipine; Nifedipine; Raynaud Disease | 1998 |
Amlodipine, a calcium channel inhibitor, and cocaine and ethanol's reinforcing effects.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Ethanol; Isradipine; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology | 1999 |
Pharmacodynamic interaction between mibefradil and other calcium channel blockers.
Topics: Amlodipine; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Cell Membrane; Dihydropyridines; Drug Interactions; Ethosuximide; Female; Gallopamil; Humans; In Vitro Techniques; Isradipine; Male; Mibefradil; Myocardial Contraction; Perfusion; Radioligand Assay; Rats; Rats, Wistar; Ventricular Pressure | 2000 |
Amlodipine inhibits thapsigargin-sensitive CA(2+) stores in thrombin-stimulated vascular smooth muscle cells.
Topics: Amlodipine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Enzyme Inhibitors; Intracellular Fluid; Isradipine; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Inbred WKY; Sarcoplasmic Reticulum; Signal Transduction; Thapsigargin; Thrombin; Verapamil | 2000 |
Role of L-type calcium channel blocking in epidermal growth factor receptor-independent activation of extracellular signal regulated kinase 1/2.
Topics: Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; ErbB Receptors; Isradipine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Thrombin; Verapamil | 2005 |
Effect of calcium channel blockers on paraoxonase-1 (PON1) activity and oxidative stress.
Topics: Amlodipine; Aryldialkylphosphatase; Calcium Channel Blockers; Humans; Isradipine; Nifedipine; Nitrendipine; Oxidative Stress | 2014 |