amlodipine and ibuprofen

amlodipine has been researched along with ibuprofen in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (12.50)18.2507
2000's8 (33.33)29.6817
2010's11 (45.83)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Bennis, K; Ducki, S; Lesage, F; Vivier, D1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arosio, E; Campedelli, A; Degan, M; Lechi, A; Minuz, P; Pancera, P; Priante, F; Ribul, M1
Arosio, E; Lechi, A; Minuz, P; Pancera, P; Pirante, F; Ribul, M1
Bejer, I; Davis, S; Korman, MG; Vu, CK1
Gutkowski, W; Janion, M; Sielski, J; Stepień, A1
Kuzmanić, M; Pavlicević, I; Rumboldt, M; Rumboldt, Z1
Chang, SY; Gong, X; Osei-Yeboah, F; Paul, S; Perumalla, SR; Shi, L; Sun, CC; Sun, WJ; Zhou, Q1
Borek-Dohalska, L; Fojtikova, V; Martinkova, M; Mináriková, M; Sedláček, J; Šikut, M; Stiborová, M; Vyskočilová, E1
Kassie, GM; Kerr, M; Moffat, A; Pratt, N; Roughead, EE1
Bai, X; Huang, Z; Li, Q; Lin, X; Zhu, Y1

Reviews

3 review(s) available for amlodipine and ibuprofen

ArticleYear
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Gastrointestinal bleeding after cold biopsy.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:7

    Topics: Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Biopsy; Cold Temperature; Colonoscopy; Female; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Humans; Ibuprofen; Male; Melena; Middle Aged; Pyloric Antrum

1998

Trials

3 trial(s) available for amlodipine and ibuprofen

ArticleYear
Amlodipine and haemodynamic effects of cyclo-oxygenase inhibition.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Amlodipine; Biomarkers; Blood Pressure; Creatinine; Cross-Over Studies; Cyclooxygenase Inhibitors; Epoprostenol; Heart Rate; Hemodynamics; Humans; Hypertension; Ibuprofen; Male; Middle Aged; Outpatients; Renin; Single-Blind Method; Thromboxane A2; Ultrasonography; Vascular Resistance; Vasodilator Agents

1995
Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 54, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase Inhibitors; Epoprostenol; Heart Function Tests; Heart Rate; Humans; Hypertension; Ibuprofen; Lisinopril; Male; Middle Aged; Prostaglandins; Thromboxane A2; Thromboxane B2; Vasodilator Agents

1996
Interaction between antihypertensives and NSAIDs in primary care: a controlled trial.
    The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2008,Fall, Volume: 15, Issue:3

    Topics: Acetaminophen; Aged; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Interactions; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Lisinopril; Male; Middle Aged; Osteoarthritis; Piroxicam; Prospective Studies

2008

Other Studies

18 other study(ies) available for amlodipine and ibuprofen

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Cutaneous drug reaction case reports: from the world literature.
    American journal of clinical dermatology, 2001, Volume: 2, Issue:4

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Aged; Amlodipine; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Anticonvulsants; Antihypertensive Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; BCG Vaccine; Cefotetan; Cephamycins; Contrast Media; Cysteine; Dapsone; Diltiazem; Dipyrone; Docetaxel; Drug Eruptions; Echinacea; Enoxaparin; Female; Fructose; Glucans; Glucose; Gold Sodium Thiomalate; Humans; Ibuprofen; Icodextrin; Ioxaglic Acid; Male; Middle Aged; Minocycline; Paclitaxel; Pregnancy; Solvents; Taxoids; Topiramate; Triamcinolone; Trichloroethylene

2001
Is the intra-aortic balloon pump a method of brain protection during cardiogenic shock after drug intoxication?
    The Journal of emergency medicine, 2010, Volume: 38, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Brain Diseases; Calcium Channel Blockers; Female; Humans; Ibuprofen; Intra-Aortic Balloon Pumping; Metoprolol; Shock, Cardiogenic; Suicide, Attempted; Verapamil

2010
Dependence of tablet brittleness on tensile strength and porosity.
    International journal of pharmaceutics, 2015, Sep-30, Volume: 493, Issue:1-2

    Topics: Amlodipine; Cellulose; Drugs, Chinese Herbal; Glyburide; Ibuprofen; Porosity; Powders; Salvia miltiorrhiza; Sildenafil Citrate; Silicon Dioxide; Stearic Acids; Tablets; Tensile Strength; Theophylline

2015
The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study.
    Environmental toxicology and pharmacology, 2017, Volume: 52

    Topics: Adsorption; Alpha-Amanitin; Amlodipine; Antidotes; Aspirin; Carbamazepine; Charcoal; Digoxin; Ibuprofen; Imipramine; Oxazepam; Phenobarbital; Poisoning; Promethazine; Silicates; Theophylline

2017
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care.
    Drug safety, 2022, Volume: 45, Issue:11

    Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; Case-Control Studies; Ciprofloxacin; Diclofenac; Furosemide; Humans; Ibuprofen; Metformin; Naproxen; Omeprazole; Primary Health Care; Ramipril; Simvastatin; Spironolactone; Sulfamethoxazole; Telmisartan; Trimethoprim; Valacyclovir; Zoledronic Acid

2022
A super-hydrophilic partially reduced graphene oxide membrane with improved stability and antibacterial properties.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2022, Volume: 86, Issue:6

    Topics: Amlodipine; Anti-Bacterial Agents; Atenolol; Calcium Chloride; Carbamazepine; Chlorides; Graphite; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Membranes, Artificial; Pharmaceutical Preparations; Piperazines; Polyphenols; Salts; Sodium Chloride; Tea; Water

2022