amlodipine and felodipine

amlodipine has been researched along with felodipine in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.39)18.7374
1990's33 (45.83)18.2507
2000's24 (33.33)29.6817
2010's12 (16.67)24.3611
2020's2 (2.78)2.80

Authors

AuthorsStudies
Alker, D; Campbell, SF; Cross, PE1
Alker, D; Burges, RA; Campbell, SF; Carter, AJ; Cross, PE; Gardiner, DG1
Arrowsmith, JE; Blackburn, KJ; Burges, RA; Campbell, SF; Cross, PE; Gardiner, DG; Stubbs, JK1
Topliss, JG; Yoshida, F1
Beaumont, K; Smith, DA; van De Waterbeemd, H; Walker, DK1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Sun, H1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cheng, TO1
Cheng, CP; Little, WC1
Abrahamsson, T; Akerblom, B; Nordlander, M; Thalén, P1
Kvist, S; Mulvany, MJ; Videbaek, LM1
Høegholm, A; Nielsen, PE; Rasmussen, E; Wiinberg, N2
Huttunen, KR; Knuuttila, ML; Pernu, HE; Tiilikainen, AS1
Bainbridge, AD; Elliott, HL; Herlihy, O; Meredith, PA1
Cheng, CP; Little, WC; Noda, T; Nordlander, M; Ohno, M1
Lund-Johansen, P; Omvik, P1
Goldsmith, SR1
Cheng, CP; Elvelin, L; Little, WC; Nordlander, M1
Block, LH; Nauck, M; Rödler, S; Roth, M; Tamm, M1
Block, LH; Eickelberg, O; Erne, P; Kohler, E; Roth, M1
Matesić, D; Mrsić, J; Simonić, A; Vitezić, D; Zupan, G1
Lewis, BS1
Höher, M; Koenig, W1
Elliott, HL; Meredith, PA1
Alpers, JA; Bune, AJ; Frith, PA; McEvoy, RD; Sajkov, D; Wang, T1
White, CM1
Jacobsen, IA; Videbaek, LM1
Archambault, F; Jewell, D; Lacourcière, Y; Lefebvre, J; Poirier, L; Reed, CV1
Brodin, U; Isaksson, H; Ohman, KP; Ostergren, J; Schwan, A1
Seibold, JR; Sturgill, MG1
Aldons, PM; Burgess, ED; Girerd, X; Morgan, TO; Rehn, L; Schaefer, RM; Singh, GP; Tilvis, R1
Chen, H; Daloze, P; Dumont, L; Lapointe, N; Qi, S; Xu, D1
Boivin, JM; Zannad, F1
Ellsworth, A; Fink, KS1
Laufen, H; Riedel, KD; Scharpf, F; Schumacher, T; Yeates, R; Zimmermann, T1
Anguita Sánchez, M1
de Vries, RJ; Dunselman, PH; van Veldhuisen, DJ1
Nakamoto, H; Okada, H; Shouda, J; Sugahara, S; Suzuki, H1
Bourg, MP; Clay, DR; Lawrence, DB1
Beckey, NP; Korman, L; Parra, D1
LeLorier, J; Sheehy, O1
Arbus, GS; Blowey, D; Khattak, S; Koren, G; Lyszkiewicz, DA; Rogan, JW1
Corradi, L; Fogari, R; Malalamani, GD; Mugellini, A; Preti, P; Zoppi, A1
Williams, CD1
Isaksson, H; Nyström, FH; Ohman, KP; Ostergren, J; Schwan, A1
Faulkner, M; Hilleman, DE; Reyes, AP; Wurdeman, RL1
Florea, S; Raicu, M1
Basavaiah, K; Chandrashekar, U; Prameela, HC1
Annis, LG; Blivin, SJ; Lyons, F; Pippins, J1
Manzo, BA; Matalka, MS; Ravnan, SL1
Coletta, E; Leenen, FH; White, R1
Bremer, T; Diamond, C; Kask, K; Man, A1
Borbas, E; Handrock, R; Klebs, S; Schaetzl, R; Trenkwalder, P1
Coletta, E; Leenen, FH1
Baron, JA; Bøtker, HE; Jensen, LO; Johansen, MB; Kaltoft, A; Maeng, M; Robertson, DJ; Schmidt, M; Sørensen, HT; Tilsted, HH1
Chen, W; Fang, H; Liu, X; Xu, W1
Cheng, KC; Cheng, KH; Cheng, KY; Lai, WT; Lee, CW; Yang, YH1
Abreu-Villela, R; Adler, C; Caraballo, I; Kuentz, M1
de Souza, RC; Ferreira, DC; Fischer, RG; Gonçalves, LS; Vidal, F1
Abbas, N; Akhtar, F; Bukhari, NI; Gilani, SAN; Javed, A; Kanwal, U; Shamim, R1
Tchernev, G1

Reviews

7 review(s) available for amlodipine and felodipine

ArticleYear
Property-based design: optimization of drug absorption and pharmacokinetics.
    Journal of medicinal chemistry, 2001, Apr-26, Volume: 44, Issue:9

    Topics: Animals; Biological Transport; Blood Proteins; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane; Drug Design; Eye; Humans; Intestinal Absorption; Models, Biological; Models, Molecular; Nasal Mucosa; Pharmaceutical Preparations; Pharmacokinetics; Prodrugs; Skin Absorption

2001
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Vascular versus myocardial effects of calcium antagonists.
    Drugs, 1994, Volume: 47 Suppl 4

    Topics: Amlodipine; Animals; Dogs; Felodipine; Heart Failure; Hemodynamics; Humans; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Pressoreceptors; Ventricular Function, Left

1994
Vascular selective calcium entry blockers in the treatment of cardiovascular disorders: focus on felodipine.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:5

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Disease; Felodipine; Heart Failure; Hemodynamics; Humans; Hypertension; Myocardial Contraction; Nifedipine; Vasodilation

1995
Calcium antagonists in patients with left ventricular dysfunction: back on the bridge?
    Journal of cardiac failure, 1996, Volume: 2, Issue:4 Suppl

    Topics: Amlodipine; Calcium Channel Blockers; Felodipine; Humans; Myocardial Infarction; Ventricular Dysfunction, Left

1996
Calcium channel blockers in left ventricular dysfunction or congestive heart failure.
    Connecticut medicine, 1997, Volume: 61, Issue:10

    Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Felodipine; Heart Failure; Humans; Nicardipine; Nifedipine; Ventricular Dysfunction, Left; Verapamil

1997
Efficacy and safety of calcium channel blockers in heart failure: focus on recent trials with second-generation dihydropyridines.
    American heart journal, 2000, Volume: 139, Issue:2 Pt 1

    Topics: Amlodipine; Calcium Channel Blockers; Dihydropyridines; Exercise Test; Exercise Tolerance; Felodipine; Heart Failure; Hemodynamics; Humans; Ventricular Function, Left

2000

Trials

21 trial(s) available for amlodipine and felodipine

ArticleYear
Comparative effects of amlodipine and felodipine ER on office and ambulatory blood pressure in patients with mild to moderate hypertension. Danish Multicentre Group.
    Journal of human hypertension, 1995, Volume: 9 Suppl 1

    Topics: Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Felodipine; Female; Humans; Hypertension; Male; Middle Aged

1995
A comparative assessment of amlodipine and felodipine ER: pharmacokinetic and pharmacodynamic indices.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:5

    Topics: Aged; Amlodipine; Blood Pressure; Delayed-Action Preparations; Felodipine; Female; Heart Rate; Humans; Male; Middle Aged

1993
Office and ambulatory blood pressure: a comparison between amlodipine and felodipine ER. Danish Multicentre Group.
    Journal of human hypertension, 1995, Volume: 9, Issue:8

    Topics: Adult; Aged; Amlodipine; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Delayed-Action Preparations; Diastole; Double-Blind Method; Drug Administration Schedule; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Office Visits; Systole; Treatment Outcome

1995
Effect of amlodipine and felodipine on sympathetic activity and baroreflex function in normal humans.
    American journal of hypertension, 1995, Volume: 8, Issue:9

    Topics: Adult; Amlodipine; Analysis of Variance; Baroreflex; Calcium Channel Blockers; Double-Blind Method; Felodipine; Head-Down Tilt; Hemodynamics; Humans; Male; Norepinephrine; Sympathetic Nervous System

1995
Felodipine and amlodipine in stable angina pectoris: results of a randomized double-blind crossover trial.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Electrocardiography, Ambulatory; Felodipine; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Prospective Studies; Treatment Outcome

1997
Amlodipine--does the effect-time profile directly reflect the concentration-time profile throughout a 24-hour period?
    Clinical cardiology, 1994, Volume: 17, Issue:9 Suppl 3

    Topics: Aged; Amlodipine; Double-Blind Method; Felodipine; Female; Humans; Male; Middle Aged; Time Factors

1994
A comparison of two long-acting vasoselective calcium antagonists in pulmonary hypertension secondary to COPD.
    Chest, 1997, Volume: 111, Issue:6

    Topics: Aged; Amlodipine; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Felodipine; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middle Aged; Patient Selection; Single-Blind Method; Vasodilator Agents

1997
Crossover comparison of the pharmacokinetics of amlodipine and felodipine ER in hypertensive patients.
    International journal of clinical pharmacology and therapeutics, 1997, Volume: 35, Issue:11

    Topics: Adult; Amlodipine; Antihypertensive Agents; Area Under Curve; Blood Pressure; Cross-Over Studies; Delayed-Action Preparations; Felodipine; Female; Half-Life; Humans; Hypertension; Male; Middle Aged

1997
Comparative effects of felodipine ER, amlodipine and nifedipine GITS on 24 h blood pressure control and trough to peak ratios in mild to moderate ambulatory hypertension: a forced titration study.
    The Canadian journal of cardiology, 1998, Volume: 14, Issue:5

    Topics: Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Delayed-Action Preparations; Felodipine; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Outpatients; Treatment Outcome

1998
Effect of amlodipine versus felodipine extended release on 24-hour ambulatory blood pressure in hypertension.
    American journal of hypertension, 1998, Volume: 11, Issue:6 Pt 1

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Felodipine; Female; Humans; Hypertension; Male; Middle Aged

1998
Improved tolerability of felodipine compared with amlodipine in elderly hypertensives: a randomised, double-blind study in 535 patients, focusing on vasodilatory adverse events. The International Study Group.
    International journal of clinical practice, 1998, Volume: 52, Issue:6

    Topics: Aged; Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dizziness; Double-Blind Method; Edema; Felodipine; Female; Headache; Humans; Hypertension; Male

1998
Ambulatory 24-h blood pressure assessment of the felodipine-metoprolol combination versus amlodipine in mild to moderate hypertension. Lorraine General Physician Investigators Group.
    Journal of hypertension, 1999, Volume: 17, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged

1999
The pharmacokinetics of extended-release formulations of calcium antagonists and of amlodipine in subjects with different gastrointestinal transit times.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:10

    Topics: Adult; Amlodipine; Area Under Curve; Biological Availability; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Felodipine; Female; Gastrointestinal Diseases; Gastrointestinal Transit; Headache; Humans; Male; Middle Aged; Time Factors

1999
Patterns of amlodipine and felodipine use in an elderly Quebec population.
    The Canadian journal of cardiology, 2000, Volume: 16, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Felodipine; Female; Humans; Hypertension; Male; Patient Compliance; Quebec

2000
A randomized prospective crossover trial of amlodipine in pediatric hypertension.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 14, Issue:12

    Topics: Adolescent; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Child; Cross-Over Studies; Felodipine; Female; Humans; Hypertension; Male; Nifedipine; Patient Compliance; Prospective Studies

2000
Effects of different dihydropyridine calcium antagonists on plasma norepinephrine in essential hypertension.
    Journal of hypertension, 2000, Volume: 18, Issue:12

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrobenzenes; Norepinephrine; Piperazines; Sympathetic Nervous System

2000
Less difference between office and ambulatory blood pressure in women than in men both before and during antihypertensive treatment.
    Blood pressure, 2000, Volume: 9, Issue:6

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Office Visits; Sex Factors; Single-Blind Method

2000
Sympatho-excitatory responses to once-daily dihydropyridines in young versus older hypertensive patients: amlodipine versus felodipine extended release.
    Journal of hypertension, 2006, Volume: 24, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amlodipine; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiovascular Physiological Phenomena; Creatinine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sympathetic Nervous System

2006
Combination of amlodipine 10 mg and valsartan 160 mg lowers blood pressure in patients with hypertension not controlled by an ACE inhibitor/CCB combination.
    Blood pressure. Supplement, 2008, Volume: 2

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Resistance; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Tetrazoles; Treatment Outcome; Valine; Valsartan

2008
Pharmacokinetic and antihypertensive profile of amlodipine and felodipine-ER in younger versus older patients with hypertension.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:6

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Single-Blind Method; Young Adult

2010
The efficacy and safety of arotinolol combined with a different calcium channel blocker in the treatment of Chinese patients with essential hypertension: a one-year follow-up study.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Asian People; Blood Pressure; Calcium Channel Blockers; China; Circadian Rhythm; Drug Therapy, Combination; Essential Hypertension; Felodipine; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propanolamines; Treatment Outcome

2014

Other Studies

44 other study(ies) available for amlodipine and felodipine

ArticleYear
Long-acting dihydropyridine calcium antagonists. 6. Structure-activity relationships around 4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-2-[(2-hydroxyethoxy)methyl]-5 -(methoxycarbonyl)-6-methyl-1,4-dihydropyridine.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Heart Rate; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship

1991
Long-acting dihydropyridine calcium antagonists. 4. Synthesis and structure-activity relationships for a series of basic and nonbasic derivatives of 2-[(2-aminoethoxy)methyl]-1,4-dihydropyridine calcium antagonists.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:2

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Chemical Phenomena; Chemistry; Dihydropyridines; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Time Factors; Vasodilator Agents

1990
Long-acting dihydropyridine calcium antagonists. 1. 2-Alkoxymethyl derivatives incorporating basic substituents.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Amlodipine; Animals; Biological Assay; Biological Availability; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Dogs; Guinea Pigs; Hemodynamics; Kinetics; Male; Nifedipine; Pyridines; Rats; Vasoconstriction

1986
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
All calcium channel blockers are not alike.
    International journal of cardiology, 1991, Volume: 32, Issue:2

    Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Heart Failure; Humans; Nifedipine

1991
Vascular versus myocardial selectivity of dihydropyridine calcium antagonists as studied in vivo and in vitro.
    Pharmacology & toxicology, 1995, Volume: 76, Issue:1

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Felodipine; Heart; Heart Rate; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Organ Specificity; Rats; Rats, Inbred SHR

1995
Time course of action of amlodipine and felodipine in the rat is most rapid in small arteries.
    European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3

    Topics: Amlodipine; Analysis of Variance; Animals; Aorta; Calcium; Calcium Channel Blockers; Felodipine; Linear Models; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Rats; Rats, Wistar; Software; Time Factors; Vascular Resistance

1995
Drug-induced gingival overgrowth and class II major histocompatibility antigens.
    Transplantation, 1994, Jun-27, Volume: 57, Issue:12

    Topics: Adult; Amlodipine; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Felodipine; Female; Gingiva; Gingival Diseases; Histocompatibility Testing; HLA-DR Antigens; Humans; Kidney Transplantation; Male; Nifedipine; Retrospective Studies; Risk Factors

1994
Comparison of effects of dihydropyridine calcium antagonists on left ventricular systolic and diastolic performance.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Felodipine; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Myocardial Contraction; Nifedipine

1994
Long-term hemodynamic effects at rest and during exercise of newer antihypertensive agents and salt restriction in essential hypertension: review of epanolol, doxazosin, amlodipine, felodipine, diltiazem, lisinopril, dilevalol, carvedilol, and ketanserin.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Benzeneacetamides; Carbazoles; Carvedilol; Diet, Sodium-Restricted; Diltiazem; Dipeptides; Doxazosin; Exercise; Felodipine; Female; Hemodynamics; Humans; Hypertension; Ketanserin; Labetalol; Lisinopril; Longitudinal Studies; Male; Middle Aged; Propanolamines

1993
Ca(2+)-channel blockers modulate the expression of interleukin-6 and interleukin-8 genes in human vascular smooth muscle cells.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:10

    Topics: Adrenergic beta-Antagonists; Amlodipine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Diuretics; Felodipine; Fibroblasts; Furosemide; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Isradipine; Lung; Muscle Proteins; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Propranolol; Transcription, Genetic

1995
Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: Amlodipine; Becaplermin; Calcium Channel Blockers; Cells, Cultured; Collagen; Collagenases; Dihydropyridines; Diltiazem; Enzyme Activation; Extracellular Matrix; Felodipine; Fibroblasts; Humans; Kinetics; Lung; Metalloendopeptidases; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Platelet-Derived Growth Factor; Procollagen; Proline; Proto-Oncogene Proteins c-sis; Transcription, Genetic; Verapamil

1996
Effects of nimodipine, felodipine and amlodipine on electroconvulsive shock-induced amnesia in the rat.
    European journal of pharmacology, 1996, Aug-29, Volume: 310, Issue:2-3

    Topics: Amlodipine; Amnesia; Animals; Calcium Channel Blockers; Electroconvulsive Therapy; Felodipine; Nimodipine; Rats; Rats, Wistar

1996
Rational use of calcium-channel antagonists in Raynaud's phenomenon.
    Current opinion in rheumatology, 1998, Volume: 10, Issue:6

    Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Humans; Isradipine; Nicardipine; Nifedipine; Raynaud Disease

1998
Immunomodulating effects of second-generation calcium channel blockers on experimental heart transplantation.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1999, Volume: 31, Issue:3

    Topics: Adjuvants, Immunologic; Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Cyclosporine; Diltiazem; Drug Therapy, Combination; Felodipine; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Mibefradil; Rats; Rats, Inbred Lew; Tetrahydronaphthalenes; Time Factors

1999
Antihypertensive treatment and CHD in the elderly.
    American family physician, 1999, Sep-15, Volume: 60, Issue:4

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Complications; Double-Blind Method; Felodipine; Fosinopril; Humans; Hypertension; Myocardial Infarction; Nisoldipine; Nitrendipine; Randomized Controlled Trials as Topic

1999
[Arterial hypertension and systolic left ventricular dysfunction: therapeutic approach].
    Revista espanola de cardiologia, 1999, Volume: 52 Suppl 3

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Carbazoles; Carvedilol; Clinical Trials as Topic; Databases, Bibliographic; Felodipine; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Meta-Analysis as Topic; Propanolamines; Randomized Controlled Trials as Topic; Risk Factors; Systole; Vasodilator Agents; Ventricular Dysfunction, Left

1999
Incidence of gingival hyperplasia caused by calcium antagonists in continuous ambulatory peritoneal dialysis patients.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1999, Volume: 15

    Topics: Adult; Amlodipine; Calcium Channel Blockers; Cardiovascular Diseases; Felodipine; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Peritoneal Dialysis, Continuous Ambulatory

1999
Outcomes of an amlodipine-to-felodipine therapeutic interchange program.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2000, Sep-01, Volume: 57, Issue:17

    Topics: Aged; Amlodipine; Antihypertensive Agents; Chi-Square Distribution; Confidence Intervals; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Program Evaluation; Retrospective Studies; Therapeutic Equivalency; Treatment Outcome

2000
Retrospective evaluation of the conversion of amlodipine to alternative calcium channel blockers.
    Pharmacotherapy, 2000, Volume: 20, Issue:9

    Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Felodipine; Female; Humans; Hypertension; Male; Nifedipine; Retrospective Studies

2000
Costs and outcomes of switching from amlodipine to felodipine.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2000, Dec-15, Volume: 57, Issue:24

    Topics: Amlodipine; Calcium Channel Blockers; Cardiovascular Diseases; Felodipine; Humans; Treatment Outcome

2000
Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.
    Journal of human hypertension, 2001, Volume: 15, Issue:8

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Calcium Channel Blockers; Costs and Cost Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Treatment Outcome

2001
Deleterious effects of nifedipine on smooth muscle cells implies alterations of intracellular calcium signaling.
    Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:6

    Topics: Amlodipine; Aorta; Caffeine; Calcium; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Cells, Cultured; Endoplasmic Reticulum; Enzyme Inhibitors; Felodipine; Genistein; Humans; Muscle, Smooth, Vascular; Nifedipine; Protein-Tyrosine Kinases; Thapsigargin

2001
Dihydropyridines are not substitutable without careful monitoring.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2002, Volume: 92, Issue:8

    Topics: Adverse Drug Reaction Reporting Systems; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Felodipine; Humans; Nifedipine

2002
Sensitive spectrophotometric determination of amlodipine and felodipine using iron(III) and ferricyanide.
    Farmaco (Societa chimica italiana : 1989), 2003, Volume: 58, Issue:2

    Topics: Amlodipine; Felodipine; Ferric Compounds; Ferricyanides; Spectrophotometry

2003
A comparative analysis of amlodipine and felodipine in a military outpatient population: efficacy, outcomes, and cost considerations.
    Military medicine, 2003, Volume: 168, Issue:7

    Topics: Amlodipine; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cost Control; Drug Costs; Felodipine; Female; Florida; Hospitals, Military; Humans; Hypertension; Male; Medical Audit; Middle Aged; Military Personnel; Naval Medicine; Retrospective Studies; Statistics, Nonparametric; Treatment Outcome

2003
Evaluation of a therapeutic conversion from amlodipine to felodipine.
    Pharmacotherapy, 2003, Volume: 23, Issue:11

    Topics: Aged; Amlodipine; Blood Pressure; Data Collection; Drug Evaluation; Felodipine; Heart Rate; Humans; Hypertension; Male; Middle Aged; Patient Satisfaction; Retrospective Studies

2003
CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension.
    Pharmacogenomics, 2006, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Felodipine; Female; Genotype; Haplotypes; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Retrospective Studies

2006
Use of clopidogrel and calcium channel blockers and risk of major adverse cardiovascular events.
    European journal of clinical investigation, 2012, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Cardiovascular Diseases; Child; Child, Preschool; Clopidogrel; Cohort Studies; Denmark; Drug Interactions; Felodipine; Female; Humans; Infant; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk; Stents; Ticlopidine; Verapamil; Young Adult

2012
Long-term outcomes of lercanidipine versus other calcium channel blockers in newly diagnosed hypertension: a nationwide cohort study.
    Current medical research and opinion, 2017, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Cohort Studies; Dihydropyridines; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Stroke; Taiwan; Young Adult

2017
Electron microscopy/energy dispersive X-ray spectroscopy of drug distribution in solid dispersions and interpretation by multifractal geometry.
    Journal of pharmaceutical and biomedical analysis, 2018, Feb-20, Volume: 150

    Topics: Amlodipine; Crystallography, X-Ray; Dosage Forms; Drug Carriers; Drug Compounding; Felodipine; Fractals; Glyburide; Indomethacin; Methylcellulose; Microscopy, Electron, Scanning; Pharmaceutical Preparations; Powder Diffraction; Solubility; Spectrometry, X-Ray Emission; Technology, Pharmaceutical

2018
Influence of 3 calcium channel blockers on gingival overgrowth in a population of severe refractory hypertensive patients.
    Journal of periodontal research, 2018, Volume: 53, Issue:5

    Topics: Adult; Aged; Amlodipine; Brazil; Calcium Channel Blockers; Felodipine; Female; Gingival Overgrowth; Humans; Hypertension; Male; Middle Aged; Nifedipine; Periodontal Index

2018
Development of Simple Dissolution Methods for Felodipine and Combined Amlodipine Besylate-Indapamide Extended Release Tablets without Stationary (Felodipine) Basket.
    Current pharmaceutical design, 2022, Volume: 28, Issue:24

    Topics: Amlodipine; Felodipine; Humans; Indapamide; Solubility; Tablets

2022
THE NITROSAMINE CONTAMINATION IN BETA BLOCKERS (BISOPROLOL/METOPROLOL), ACE INHIBITORS (LISINOPRIL/PERINDOPRIL), THIAZIDES DIURETICS (HCT), CALCIUM CHANNEL BLOCKERS (AMLODIPINE/FELODIPINE), SARTANS (CANDESARTAN) AND ТHE SUBSEQUENT SKIN CANCER DEVELOPMENT
    Georgian medical news, 2023, Issue:337

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bisoprolol; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Felodipine; Humans; Lisinopril; Melanoma; Metoprolol; Nitrosamines; Perindopril; Prospective Studies; Skin Neoplasms; Sodium Chloride Symporter Inhibitors; Thiazides

2023