amlodipine has been researched along with dihydropyridines in 235 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.13) | 18.7374 |
| 1990's | 33 (14.04) | 18.2507 |
| 2000's | 84 (35.74) | 29.6817 |
| 2010's | 100 (42.55) | 24.3611 |
| 2020's | 13 (5.53) | 2.80 |
| Authors | Studies |
|---|---|
| Heynen, G | 1 |
| Mason, RP; Moisey, DM; Shajenko, L | 1 |
| Arena, JP; Chin, S; Kass, RS | 2 |
| Herbette, LG; Mason, RP; Moring, J | 1 |
| Bolger, GT; O'Neill, SK | 1 |
| Gambini, F; Gaviraghi, G; Micheli, D; Quartaroli, M; Tarter, G; Trist, DG | 1 |
| Alker, D; Beresford, AP; Kobylecki, RJ; Macrae, PV | 1 |
| Fleckenstein, A; Fleckenstein-Grün, G; Frey, M; Zorn, J | 1 |
| Matlib, MA | 1 |
| Arrowsmith, JE; Blackburn, KJ; Burges, RA; Campbell, SF; Cross, PE; Gardiner, DG; Stubbs, JK | 1 |
| Lombardo, D; Raimondi, F | 1 |
| Hattori, K; Maruyama, K; Nagatomo, T; Qu, YL; Sugiyama, K; Takamizawa, C; Watanabe, K | 1 |
| Karasawa, A; Moriyama, T | 1 |
| Abrahamsson, T; Akerblom, B; Nordlander, M; Thalén, P | 1 |
| Bangalore, R; Glossmann, H; Kass, RS; Kwan, YW; Lakitsh, M | 1 |
| Elliott, HL | 1 |
| Mason, RP | 1 |
| Locher, R; Lupo, E; Vetter, W; Weisser, B | 1 |
| Gaviraghi, G; Giacometti, A; Micheli, D; Trist, DG | 1 |
| Vetrovec, GW | 1 |
| Bachetti, T; Carboni, L; Ferri, S; Ratti, E; Spampinato, S; Van Amsterdam, FT | 1 |
| Block, LH; Nauck, M; Rödler, S; Roth, M; Tamm, M | 1 |
| Block, LH; Eickelberg, O; Erne, P; Kohler, E; Roth, M | 1 |
| Gilar, M; Tesarová, E; Uhrová, M | 1 |
| Cheung, BM; Lau, CP | 1 |
| Karasawa, A; Kusaka, H; Nomura, H | 1 |
| Fujiki, H; Hirano, T; Miyakoda, G; Mori, T; Ohura, M; Orito, K | 1 |
| Crouzel, C; Dollé, F; Duval, R; Fuseau, C; Hinnen, F; Péglion, JL; Valette, H | 1 |
| Heath, B; Kass, RS; Xia, J | 1 |
| Haraguchi, K; Iga, T; Ito, K; Kotaki, H; Sawada, Y | 1 |
| Fujiki, H; Hata, F; Hirano, T; Miyakoda, G; Mori, T; Nakaya, Y; Ohura, M; Orito, K; Satake, H; Sumida, T; Takeuchi, T; Yamamura, Y; Yoshida, K | 1 |
| Böhm, M; Bräsen, JH; Griendling, KK; Harrison, DG; Heitzer, T; Macharzina, R; Meinertz, T; Münzel, T; Nickenig, G; Schulz, E; Skatchkov, M; Stasch, JP; Warnholtz, A | 1 |
| Miho, N; Nawada, R; Obayashi, K; Sakata, K; Shirotani, M; Togi, K; Yoshida, H | 1 |
| Karasawa, A; Kobayashi, S; Kosaka, N; Nito, M; Nomura, H; Sonoda, R; Tanaka, H; Yamaguchi, K | 1 |
| Christians, T; Diewald, D; Holzgrabe, U; Lehmann, J; Otte, Y; Wessler, C | 1 |
| Birkenhäger, WH; Fagard, RH; Staessen, JA | 1 |
| Fukuo, K; Morimoto, S; Niinobu, T; Ogihara, T; Suhara, T; Yang, J | 1 |
| de Vries, RJ; Dunselman, PH; van Veldhuisen, DJ | 1 |
| Di Nicola, G; Joffe, BI; Klug, E; Panz, V; Stankovic, S | 1 |
| Fukuzawa, M; Miyaguchi, S; Nakazawa, T; Ohta, S; Qiang, X; Sakata, Y; Satoh, J; Takahashi, K; Takizawa, Y; Toyota, T | 1 |
| Antepohl, W; Haaf, O; Herzig, S; Huber, I; Matthes, J; Striessnig, J | 1 |
| Hirano, K; Kimura, R; Ohashi, K; Urayama, A; Watanabe, H; Yamada, S | 1 |
| Araki, H; Futagami, K; Gomita, Y; Kawasaki, H; Kurosaki, Y; Nakatsuma, A | 1 |
| Corradi, L; Fogari, R; Malalamani, GD; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Kumari, S; Malhotra, S; Pandhi, P | 1 |
| Hirano, T; Kambe, T; Mori, T; Nakayama, N; Schwartz, A; Takase, H; Toide, K | 1 |
| Andrésdóttir, MB; Huysmans, FT; Valk, IM; van de Bosch, WJ; van Hamersvelt, HW; van Helden, MJ | 1 |
| Garcha, RS; Hughes, AD; Sever, PS | 1 |
| De Cesaris, R; La Commare, P; Omboni, S; Palatini, P; Zanchetti, A | 1 |
| Agabiti-Rosei, E; Castellano, M; de Kam, PJ; Fallon, M; Fluckiger, L; Hausberg, M; Heitmann, J; Lefrandt, JD; Murphy, M; Rahn, KH; Rostrup, M; Sevre, K; Smit, AJ; Urbigkeit, A; van Roon, AM; Zannad, F | 1 |
| Godfraind, T; Krenek, P; Kyselovic, J; Wibo, M | 1 |
| Doba, N; Kimura, Y; Kinouchi, T; Kuwabara, Y; Kuwata, S; Maruyama, C; Tomiyama, H; Yoshida, H; Yoshida, Y | 1 |
| Bakris, GL; Epstein, M; Goldberg, R; Hung, E; Preston, R; Richardson, DJ; Smith, AC | 1 |
| Christians, T; Holzgrabe, U | 1 |
| Kimura, R; Kusaka, T; Nakajima, M; Uchida, S; Yamada, S | 1 |
| Bianchetti, MG; Edefonti, A; Fossali, E; Vogt, B; von Vigier, RO | 1 |
| Leonetti, G; Magnani, B; Pessina, AC; Rappelli, A; Trimarco, B; Zanchetti, A | 1 |
| Szász, G | 1 |
| Zanchetti, A | 1 |
| Asakura, M; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Liao, Y; Minamino, T; Node, K; Ogai, A; Ogita, H; Sanada, S; Takashima, S | 1 |
| Campagnola, M; Cominacini, L; Davoli, A; Fratta Pasini, A; Garbin, U; Lo Cascio, V; Nava, C; Pastorino, AM; Rossato, P | 1 |
| Hirai, A; Ichikawa, S; Kanada, S; Kuramoto, K; Nakachi, T; Ogihara, T | 1 |
| Helberg, S; Istad, H; Lund-Johansen, P; Madsbu, S; Risberg, K; Rønnevik, PK; Stranden, E; Wessel-Aas, T | 1 |
| Boatto, G; de Caprariis, P; Faedda, MV; Nieddu, M | 1 |
| Balbarini, A; Dell'Omo, G; Mariani, M; Menegato, A; Nuti, M; Pedrinelli, R | 1 |
| Inomata, K; Tanaka, H | 1 |
| Shigematsu, M; Takami, T | 1 |
| Imaizumi, T; Inagaki, Y; Nakamura, K; Yamagishi, S | 1 |
| Kojima, S; Shida, M; Yokoyama, H | 1 |
| Miyachi, Y; Ueshiba, H | 1 |
| Fukumoto, Y; Ito, A; Shimokawa, H | 1 |
| Enomoto, A; Konda, T; Matsushita, J; Moriyama, T; Takahara, A | 1 |
| Brazdzionyte, J; Jurkevicius, R; Zabiela, V; Zaliūnas, R | 1 |
| Brazdzionyte, J; Jurkevicus, R; Zabiela, V; Zaliunas, R | 1 |
| Brixius, K; Geissler, HJ; Gross, T; Hekmat, K; Mehlhorn, U; Schwinger, RH; Tossios, P | 1 |
| Asayama, J; Inoue, R; Kobara, M; Miki, S; Nakagawa, Y; Nakata, T; Shimizu, T; Toba, H; Yoshimura, A | 1 |
| Aizawa, Y; Gurusamy, N; Kamal, FA; Kodama, M; Kunisaki, M; Ma, M; Mito, S; Palaniyandi, SS; Prakash, P; Veeraveedu, PT; Wahed, MI; Watanabe, K; Wen, J | 1 |
| Eguchi, K; Hoshide, S; Ishikawa, J; Kario, K; Shimada, K | 1 |
| Abe, Y; Fan, YY; Fujisawa, Y; Kimura, S; Kiyomoto, H; Kohno, M; Nishiyama, A; Rahman, M; Shokoji, T; Sun, GP | 1 |
| Ito, T; Kataoka, K; Kim-Mitsuyama, S; Lai, ZF; Ogawa, H; Tanaka, T; Tokutomi, Y; Yamamoto, E; Yamashita, T | 1 |
| Hayashi, K; Iigaya, K; Kumagai, H; Onami, T; Takimoto, C | 1 |
| Inoue, T; Kobayashi, K; Nakamoto, H; Shoda, J; Suzuki, H | 1 |
| Aizawa, Y; Atarashi, H; Fukatani, M; Hirai, M; Hirayama, A; Inoue, H; Kamakura, S; Kato, T; Kodama, I; Koretsune, Y; Kumagai, K; Kurachi, Y; Mitamura, H; Nakaya, H; Ogawa, S; Ohe, T; Ohtsu, H; Okumura, K; Saikawa, T; Sakurai, M; Sugi, K; Watanabe, E; Yamashita, T; Yamazaki, T | 1 |
| Ikeda, J; Matsubara, M; Yao, K | 2 |
| Ishibashi, T; Nishio, M; Yoshida, J | 1 |
| Yamagishi, T | 1 |
| Inoue, T; Kawagoe, Y; Koide, H; Nakamura, T; Node, K; Sugaya, T; Suzuki, T; Ueda, Y | 1 |
| Eguchi, K; Fukuda, T; Hoshide, S; Ishikawa, J; Kario, K; Numao, T; Shimada, K; Tomizawa, H | 1 |
| Alberici, M; Lembo, G; Payeras, AC; Sladek, K | 1 |
| Akashiba, A; Ishimitsu, T; Kameda, T; Matsuoka, H; Minami, J; Numabe, A; Ohta, S; Ono, H; Takahashi, T; Yoshii, M | 1 |
| Iwasaka, T; Maki, K; Morimoto, S; Yano, Y | 1 |
| Fujitani, Y; Hirose, T; Kanazawa, A; Kawamori, R; Ohmura, C; Sakai, K; Shimizu, T; Uchino, H; Watada, H | 1 |
| Abe, K; Deguchi, K; Hayashi, T; Kamiya, T; Lukic-Panin, V; Sehara, Y; Tsuchiya, A; Yamashita, T; Zhang, H | 1 |
| Fujii, M; Horie, M; Sakai, H; Tanaka, T; Tsutamoto, T; Yamamoto, T | 1 |
| Borekci, B; Cadirci, E; Halici, Z; Ozdemir, Y; Suleyman, H | 1 |
| Ando, K; Fujita, T; Ideura, T; Isshiki, M; Nishimura, H; Takahashi, K; Yasuda, G | 1 |
| Ali, N; Palit, P | 1 |
| Fujiwara, H; Hattori, A; Hiei, K; Io, K; Kato, T; Kawasaki, M; Matsuo, H; Minatoguchi, S; Morita, N; Nishigaki, K; Noda, T; Ojio, S; Ono, H; Sato, H; Segawa, T; Takemura, G; Tanaka, T; Ueno, K; Watanabe, S | 1 |
| Hayashi, N; Ito, N; Katsuya, T; Ogihara, T; Ohishi, M; Rakugi, H; Shiota, A; Takagi, T; Tatara, Y; Terai, M | 1 |
| Dickson, M; Plauschinat, CA | 1 |
| Barrios, V; Calderón, A; de la Figuera, M; Escobar, C; Honorato, J; Llisterri, JL; Segura, J | 2 |
| Fukumoto, Y; Ito, A; Shimokawa, H; Yasuda, S | 1 |
| Cadirci, E; Halici, Z; Suleyman, H | 1 |
| Martinez-Martin, FJ; Saiz-Satjes, M | 1 |
| Furuno, M; Higaki, J; Horiuchi, M; Inaba, S; Iwai, M; Kanno, H; Mogi, M; Okayama, H; Senba, I; Tomono, Y | 1 |
| Ishii, K; Kawakami, T; Kuwagata, M; Nakahara, T; Saito, M; Sakamoto, K; Shimada, M; Yamaguchi, A | 1 |
| Abe, M; Maruyama, N; Maruyama, T; Matsumoto, K; Okada, K | 1 |
| Chiba, S; Fujisawa, M; Koike, H; Yorikane, R | 1 |
| Aritomi, S; Enomoto, A; Koganei, H; Konda, T; Niinuma, K; Nitta, K; Ogawa, T | 1 |
| Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tanaka, T; Tsutamoto, T; Yamaji, M; Yamamoto, T | 1 |
| Fujita, T; Fujito, T; Hishikawa, K; Idei, M; Takase, O | 1 |
| Martínez Martín, FJ | 1 |
| Araki, N; Furuya, D; Ohkubo, T; Shimazu, K; Takei, K; Tamura, N; Yamamoto, T; Yanagisawa, CT | 1 |
| Ban, N; Endo, K; Kawana, H; Miyashita, Y; Nagayama, D; Ohhira, M; Oyama, T; Saiki, A; Sasaki, H; Shirai, K; Yamaguchi, T | 1 |
| Daida, H; Fujiwara, Y; Inoue, K; Kawamura, M; Kojima, T; Kurata, T; Miyauchi, K; Nakazato, Y; Okazaki, S; Sumiyoshi, M; Suwa, S; Tanimoto, K; Yamagami, S; Yokoyama, K; Yokoyama, T | 1 |
| Akie, Y; Aritomi, S; Nakamura, Y; Nakayama, A; Satoh, Y; Sugiyama, A; Takahara, A; Wagatsuma, H | 1 |
| Hoshino, C; Kikuchi, A; Kuriyama, C; Ohta, M; Sato, N; Sugawara, S | 1 |
| Ishizaka, T; Iwasaki, H; Kise, H; Mitsumori, Y; Nakamura, Y; Sugiyama, A; Takahara, A | 1 |
| Hirooka, Y; Sunagawa, K | 1 |
| Araki, N; Ito, Y | 1 |
| Furukawa, T; Kamegaya, E; Miyashita, Y; Nukada, T; Yoshii, M | 1 |
| Dohi, Y; Kimura, G; Miyagawa, K; Nakazawa, A; Sato, K; Sugiura, T; Yamashita, S | 1 |
| Fujiwara, N; Kawagoe, Y; Koide, H; Nakamura, T; Sato, E; Sugaya, T; Ueda, Y; Yamada, S; Yamagishi, S | 1 |
| Bianchetti, MG; Fossali, EF; Milani, G; Ragazzi, M; Ramelli, GP; Rizzi, M; Simonetti, GD | 1 |
| Futenma, A; Imai, H; Kimura, Y; Maeda, K; Miura, N; Suga, N; Yamada, H | 1 |
| Aiba, N; Hara, M; Izumi, T; Kutsuna, T; Masuda, T; Matsumoto, T; Moriya, T; Noda, C; Ogura, MN; Takahira, N | 1 |
| Asanuma, K; Fan, YY; Fujita, T; Hitomi, H; Kobori, H; Kohno, M; Nakano, D; Nishiyama, A; Noma, T; Ohashi, N; Ohsaki, H; Suwarni, D; Tomino, Y | 1 |
| Kitakaze, M; Liao, YL; Luo, Q; Xi, F; Xuan, WL | 1 |
| Friis, S; Olsen, JH; Qian, L; Rhodes, SL; Ritz, B; Schernhammer, E | 1 |
| Jin, D; Miyazaki, M; Sakonjo, H; Takai, S | 1 |
| Inada, H; Ishimitsu, T; Matsuoka, H; Nakano, N; Ohba, S; Okamura, A; Takahashi, T | 1 |
| Arakawa, K; Fujii, M; Inoki, I; Kimura, T; Konoshita, T; Makino, Y; Miyamori, I; Nakamura, H; Wakahara, S | 1 |
| Fukumoto, Y; Inoue, Y; Minatoguchi, S; Nishigaki, K; Shimokawa, H; Sueda, S; Urata, H; Yamanouchi, Y; Yasuda, S | 1 |
| Kawano, Y; Matsuoka, H; Miwa, Y; Ohta, Y; Sasaguri, T; Tominaga, M; Tsuchihashi, T; Ueno, M | 1 |
| Aritomi, S; Koganei, H; Konda, T; Mitsui, A; Nitta, K; Ogawa, T; Wagatsuma, H | 1 |
| Laurent, S; Richy, FF | 1 |
| Cao, B; Jia, S; Li, H; Lin, Y; Qu, P; Wang, M; Wu, F; Zhao, X | 1 |
| Ceron, CS; Gerlach, RF; Guimaraes, DA; Marçal, DM; Martins-Oliveira, A; Rizzi, E; Tanus-Santos, JE | 1 |
| Abe, M; Fujita, T; Maruyama, N; Maruyama, T; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M | 1 |
| Comi-Diaz, C; Macias-Batista, A; Martinez-Martin, FJ; Pedrianes-Martin, P; Rodriguez-Rosas, H; Soriano-Perera, P | 1 |
| Inagaki, K; Kumagai, I; Makino, H; Miyoshi, T; Nakamura, E; Ogura, T; Otsuka, F; Suzuki, J; Tanabe, K; Tsukamoto, N | 1 |
| Kobara, M; Kojima, Y; Nakano, A; Nakata, T; Noda, K; Oshima, Y; Toba, H; Tojo, C; Wang, J; Yoshida, M | 1 |
| Sansanayudh, N; Veerayuthvilai, S; Wongwiwatthananukit, S | 1 |
| Aritomi, S; Konda, T; Niinuma, K; Nitta, K; Ogawa, T | 2 |
| Albayrak, F; Altunkaynak, ZB; Bayram, E; Beyzagül, P; Dursun, H; Halici, Z; Keleş, NO; Okçu, N; Süleyman, H; Ünal, B; Uyanik, A | 1 |
| Fujiwara, N; Kawagoe, Y; Koide, H; Nakamura, T; Sato, E; Takeuchi, M; Ueda, Y; Yamagishi, S | 1 |
| Daida, H; Fujiwara, Y; Hiro, T; Inoue, K; Kawamura, M; Kojima, T; Komiyama, N; Kurata, T; Miyauchi, K; Nakazato, Y; Okazaki, S; Sumiyoshi, M; Suwa, S; Tamura, H; Tanimoto, K; Yamagami, S; Yokoyama, K; Yokoyama, T | 1 |
| Ichihara, K; Kano, S; Komatsu, K; Satoh, K | 1 |
| Ando, K; Fujita, T; Haneda, M; Ito, S; Kashihara, N; Kishimoto, J; Nangaku, M; Node, K; Shimosawa, T | 1 |
| Ando, K; Babazono, T; Fujita, T; Kario, K; Matsuoka, H; Nakao, K; Tanaka, S; Ueshima, K | 1 |
| Kaneda, H; Ma, J; Morita, T | 1 |
| Saito, Y; Takami, T | 2 |
| Koriyama, H; Kyutoku, M; Mariana, OK; Morishita, R; Nakagami, F; Nakagami, H; Rakugi, H; Shimamura, M; Shimizu, H; Yasumasa, N | 1 |
| Barsys, V; Duburs, G; Garaliene, V; Jakuska, P; Krauze, A | 1 |
| Daida, H; Fukao, K; Hiki, M; Hirose, K; Kiyanagi, T; Kume, A; Kurata, T; Matsumori, R; Miyazaki, T; Ohsaka, H; Shimada, K | 1 |
| Aladejebi, O; Hockerman, GH; Lin, M | 1 |
| Fujimoto, S; Kashihara, N; Nagasu, H; Sasaki, T; Satoh, M; Tomita, N | 1 |
| Shinozaki, K | 1 |
| Chen, GL; Fan, CM; Li, HM; Li, YS; Lin, YZ; Pang, HM; Wang, L; Wu, SY; Yan, LR; Yu, J; Zhao, RP | 1 |
| Fan, HQ; Li, Y; Wang, JG; Zou, J | 1 |
| Arakawa, K; Jinnouchi, H; Jinnouchi, T; Kim-Mitsuyama, S; Matsui, K; Ogawa, H | 2 |
| Inoue, T; Kikuta, T; Kojima, E; Nodaira, Y; Ohno, Y; Okayama, M; Seto, T; Sueyoshi, K; Suzuki, H; Takane, H; Takenaka, T; Watanabe, Y | 1 |
| Hamada, T; Hasegawa, A; Hisatome, I; Ishida, K; Kato, M; Mishima, M; Miyazaki, S; Mizuta, E; Ninomiya, H; Nosaka, Y; Ogino, K; Ohtahara, A; Osaki, T; Sakata, S; Taniguchi, S; Watanabe, A; Yamada, K; Yamamoto, K; Yoshida, A | 1 |
| Daikuhara, H; Ishida, T; Kikuchi, F | 1 |
| Fujita, M; Ikai, A; Mitani, S; Miyamoto, S; Ogura, C; Ono, K; Sugimoto, N; Tanaka, S | 1 |
| Kawano, K; Kitani, M; Koshiba, K; Kusunose, K; Orino, S; Sata, M; Soeki, T; Taketani, Y; Wakatsuki, T; Yagi, S | 1 |
| Aritomi, S; Hattori, T; Ito, H; Kato, M; Murase, T; Murohara, T; Nagata, K; Nakashima, C; Nashima, K; Niinuma, K; Ohtake, M; Takahashi, K; Takatsu, M | 1 |
| Barsys, V; Benetis, R; Garaliene, V; Jakuška, P | 1 |
| Rich, MW | 1 |
| Abe, M; Inoshita, A; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Yoshida, Y | 1 |
| Daida, H; Miyauchi, K | 1 |
| Alberici, M; Ott, C; Raff, U; Ritt, M; Schmieder, RE; Schneider, MP; Striepe, K | 1 |
| Fujisawa, M; Koike, H; Matsuoka, Y; Ueno, K; Yorikane, R | 1 |
| Hiromura, K; Ikeuchi, H; Maeshima, A; Mishima, K; Miya, M; Nojima, Y; Sakurai, N | 1 |
| Aritomi, S; Harada, E; Hirano, K; Ishikawa, T; Kim-Mitsuyama, S; Kuwahara, K; Mori, Y; Nishida, M; Saiki, S; Sunggip, C | 1 |
| Iribe, G; Ito, H; Kaihara, K; Naruse, K | 1 |
| Ando, K; Fujita, T; Kosugi, S; Matsuoka, H; Nakao, K; Sato, T; Tanaka, S; Ueshima, K | 1 |
| Burnier, M | 1 |
| Barsys, V; Benetis, R; Garaliene, V; Giedraitis, S; Krauze, A | 1 |
| Ikeda, U; Izawa, A; Koyama, J; Miyashita, Y; Motoki, H; Takahashi, M; Tomita, T | 1 |
| Furusho, H; Hamaoka, T; Ikeda, T; Inomata, J; Kaneko, S; Kobayashi, D; Murai, H; Sugiyama, Y; Takamura, M; Takata, S; Usui, S | 1 |
| Ando, K; Fujita, T; Isshiki, M; Kashihara, N; Nakanishi, T; Nangaku, M; Nishizawa, Y; Nitta, K; Rakugi, H; Shimosawa, T; Takahashi, K; Tomita, K; Yokoyama, H | 1 |
| Grassi, G | 1 |
| Izumikawa, Y; Kato, H; Kojima, K; Kubo, E; Nagura, M; Nosaka, H; Shima, T; Shimada, M; Shiraishi, T; Tanemoto, M; Tomioka, S; Uchida, S; Ueda, S; Yano, H | 1 |
| Harada, E; Hattori, T; Matsuura, N; Murohara, T; Nagasawa, K; Nagata, K; Niinuma, K; Takahashi, K; Takatsu, M; Watanabe, S | 1 |
| Fujita, M; Hikita, T; Itakura, H; Ito, K; Ito, T; Mizuno, S; Mochizuki, K; Morita, T; Nakai, K; Ohno, Y; Saito, T; Shin, I; Soma, M; Sugawara, M; Takahashi, M; Takahashi, Y; Uchida, S | 1 |
| Bernard, E; Bertrand, Y; Bleyzac, N; Goutelle, S | 1 |
| Javeri, Y; Juneja, D; Nasa, P; Singh, A; Singh, O | 1 |
| Cao, TS; Huynh, VM; Tran, VH | 1 |
| Angeloni, E; Lombardo, P; Pirelli, M; Refice, S; Vitaterna, A | 1 |
| Hano, T; Iwane, N; Kawabe, T; Koike, Y; Nishihara, K | 2 |
| Albayrak, A; Ayan, AK; Aydin, A; Bayir, Y; Cadirci, E; Demirci, E; Halici, Z; Karakus, E; Ozturk-Karagoz, B; Sahin, A; Unal, D | 1 |
| Asai, S; Nakayama, T; Nishida, Y; Susa, N; Takahashi, Y; Yada, Y | 1 |
| Eguchi, A; Fujiwara, S; Hirotani, S; Komamura, K; Koshiba, M; Mano, T; Masaki, M; Masuyama, T; Sugahara, M; Tsujino, T | 1 |
| Bisenieks, E; Duburs, G; Gall Troselj, K; Krauze, A; Poikans, J; Velena, A; Zarkovic, N | 1 |
| Brajković, G; Djordjević, S; Jović-Stosić, J; Mladenov, M; Putić, V; Zivanović, D | 1 |
| Martinez-Martin, FJ; Saiz Satjes, M | 1 |
| Fujii, M; Ichikawa, M; Imagawa, M; Ishizuka, T; Kaeriyama, S; Konoshita, T; Makino, Y; Nakamura, H; Nakaya, T; Sato, S; Suzuki, J; Urabe, M; Wakahara, S; Yamada, M; Yamamoto, K; Zenimaru, Y | 1 |
| Catterall, WA; Gamal El-Din, TM; Pryde, DC; Scheuer, T; Swanson, TM; Tang, L; Zheng, N | 1 |
| Shete, MM | 1 |
| Calvo, C; Espinel, E; Esteban, R; Macias, JF; Mateos, L; Robles, NR; Sobrino, J | 1 |
| Dimitriadis, K; Mani, I; Mantzouranis, E; Tousoulis, D; Tsioufis, C; Tsioufis, K | 1 |
| Martinez-Martin, FJ; Roca-Cusachs, A; Saiz-Satjes, M | 1 |
| de Vries, C; Haerden, Y; Lins, R | 1 |
| Fendrikova, AV; Pyhalova, NE; Sirotenko, DV; Skibitsky, VV | 1 |
| Cheng, KC; Cheng, KH; Cheng, KY; Lai, WT; Lee, CW; Yang, YH | 1 |
| Cha, BS; Chung, CH; Hwang, YC; Jang, HC; Lee, KW; Lee, MK; Min, KW; Yoon, KH | 1 |
| Amari, Y; Ando, T; Ichihara, A; Iida, T; Morimoto, S | 1 |
| Asayama, K; Hanazawa, T; Hosaka, M; Imai, Y; Inoue, R; Obara, T; Ohkubo, T; Satoh, M; Watabe, D | 1 |
| Akasaka, H; Hongyo, K; Ito, N; Nozato, S; Nozato, Y; Rakugi, H; Sugimoto, K; Takami, Y; Takeda, M; Takeya, M; Takeya, Y; Yamamoto, K | 1 |
| Canbolat, S; Nurullahoglu Atalik, KE | 1 |
| Arima, H; Chaugai, S; Kerman, SRJ; Sepehry, AA; Sherpa, LY | 1 |
| Jeon, SY; Lee, NR; Yim, CY | 1 |
| Okamura, K; Shirai, K; Takamiya, Y; Urata, H; Yano, Y | 1 |
| Kario, K; Kurose, Y; Matsuda, S; Nagahama, S; Sugii, H; Suzuki, N; Teshima, T | 2 |
| Kobara, M; Nakata, T; Naseratun, N; Toba, H; Watanabe, Y | 1 |
| Abdelsattar, AT; Alamodi, AA; Masoud, AT; Mohammed, OM; Nso, N; Payton, M; Shareef, MA; Sofy, AA | 1 |
| Gao, S; Yan, N | 1 |
| Ganesan, K; Panneerpandian, P; Rao, DB | 1 |
| D, DC; Jj, NK; Kavitha, R | 1 |
| Kafle, RC; Maskey, A; Sapkota, S | 1 |
| Furui, M; Inagaki, K; Kamei, H; Matsubara, T | 1 |
| Hojnacki, D; Podolsky, R; Schaller, B; Sternberg, Z; Tian, M; Yu, J | 1 |
| Maiti, R; Maji, S; Pal, D | 1 |
| Alsanosi, S; Bird, GS; D'Agostin, D; Lip, S; Padmanabhan, S; Parekh, AB | 1 |
16 review(s) available for amlodipine and dihydropyridines
| Article | Year |
|---|---|
New drugs for hypertension--variations on old themes.
Topics: Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dihydropyridines; Doxazosin; Humans; Hypertension; Isradipine; Nifedipine; Prazosin; Verapamil | 1991 |
Dihydropyridine calcium-channel blockers for the treatment of hypertensive diabetic patients.
Topics: Amlodipine; Calcium Channel Blockers; Diabetic Angiopathies; Dihydropyridines; Enalapril; Fosinopril; Humans; Hypertension; Randomized Controlled Trials as Topic | 2000 |
Efficacy and safety of calcium channel blockers in heart failure: focus on recent trials with second-generation dihydropyridines.
Topics: Amlodipine; Calcium Channel Blockers; Dihydropyridines; Exercise Test; Exercise Tolerance; Felodipine; Heart Failure; Hemodynamics; Humans; Ventricular Function, Left | 2000 |
Pranidipine, a 1,4-dihydropyridine calcium channel blocker that enhances nitric oxide-induced vascular relaxation.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cyclic GMP; Dihydropyridines; Drug Synergism; Endothelium, Vascular; Humans; Muscle, Smooth, Vascular; Myocardial Contraction; Nitric Oxide; Vasodilation; Vasodilator Agents | 2001 |
[Novel actions of calcium channel blockers].
Topics: Amlodipine; Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Depression; Dihydropyridines; Evidence-Based Medicine; Heart Rate; Humans; Hypertension; Kidney Diseases; Proteinuria; Sympathetic Nervous System | 2006 |
[Calcium antagonists: current and future applications based on new evidence. Calcium channel blockers and autonomic nervous system].
Topics: Amlodipine; Antihypertensive Agents; Antioxidants; Autonomic Nervous System; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Heart Rate; Humans | 2010 |
[Calcium antagonists: current and future applications based on new evidence. Neuroprotective effect of calcium antagonists].
Topics: Amlodipine; Animals; Brain Edema; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cell Death; Cerebral Infarction; Dihydropyridines; Hippocampus; Humans; Neurons; Neuroprotective Agents; omega-Conotoxins; Rats | 2010 |
Prognostic effects of calcium channel blockers in patients with vasospastic angina--a meta-analysis.
Topics: Amlodipine; Angina Pectoris; Asian People; Calcium Channel Blockers; Coronary Vasospasm; Dihydropyridines; Diltiazem; Humans; Nifedipine; Prognosis; Treatment Outcome | 2010 |
Efficacy and safety profiles of manidipine compared with amlodipine: a meta-analysis of head-to-head trials.
Topics: Adult; Amlodipine; Ankle; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Edema; Humans; Hypertension; Meta-Analysis as Topic; Nitrobenzenes; Piperazines; Publication Bias; Randomized Controlled Trials as Topic; Treatment Outcome | 2011 |
Renal protection with calcium antagonists: the role of lercanidipine.
Topics: Amlodipine; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; PubMed | 2013 |
1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues-Model Compounds Targeting Oxidative Stress.
Topics: Amlodipine; Animals; Antioxidants; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cattle; Dihydropyridines; Epithelial Cells; Humans; Hydrogen; Lipoproteins, LDL; Mice; Microsomes; Mitochondria; Niacinamide; Nifedipine; Nitrobenzenes; Oxidants; Oxidative Stress; Piperazines | 2016 |
Treatment of hypertensive patients with diabetes: beyond blood pressure control and focus on manidipine.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus; Dihydropyridines; Drug Therapy, Combination; Humans; Hypertension; Nitrobenzenes; Piperazines | 2016 |
Effects of Long- and Intermediate-Acting Dihydropyridine Calcium Channel Blockers in Hypertension: A Systematic Review and Meta-Analysis of 18 Prospective, Randomized, Actively Controlled Trials.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
Amlodipine Compared with Benidipine in the Management of Hypertension: A Systematic Review and Meta-Analysis.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Renal Insufficiency, Chronic; Risk Factors; Treatment Outcome; Vasodilator Agents | 2020 |
Efficacy and Safety of Azelnidipine as an Antihypertensive Compared to Amlodipine: A Systematic Review and Meta-analysis.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension | 2023 |
A Reappraisal of the Effects of L-type Ca
Topics: Amlodipine; Antihypertensive Agents; Calcium; Calcium Channel Blockers; Dihydropyridines; Fura-2; Heart Failure; Humans; Hypertension; Prospective Studies | 2023 |
82 trial(s) available for amlodipine and dihydropyridines
| Article | Year |
|---|---|
Efficacy and safety evaluation of lacidipine compared with amlodipine in mild-to-moderate hypertensive patients.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged | 1994 |
Relative efficacy and tolerability of lacidipine and amlodipine in patients with mild-to-moderate hypertension: a randomized double-blind study.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Double-Blind Method; Female; Half-Life; Humans; Hypertension; Male; Middle Aged; Pulse | 1996 |
Effects of amlodipine and cilnidipine on cardiac sympathetic nervous system and neurohormonal status in essential hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Heart; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Reference Values; Renin; Sympathetic Nervous System | 1999 |
Amlodipine and physiological responses to brisk exercise in healthy subjects.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Exercise; Hemodynamics; Hormones; Humans; Male; Time Factors | 1999 |
Effects of different dihydropyridine calcium antagonists on plasma norepinephrine in essential hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrobenzenes; Norepinephrine; Piperazines; Sympathetic Nervous System | 2000 |
Effect of calcium antagonists on stress-induced rise in blood pressure and heart rate: a double-blind, placebo-controlled study.
Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Cold Temperature; Dihydropyridines; Double-Blind Method; Exercise; Hand Strength; Heart Rate; Humans; Stress, Psychological | 2001 |
Ankle edema formation during treatment with the calcium channel blockers lacidipine and amlodipine: a single-centre study.
Topics: Adolescent; Adult; Aged; Amlodipine; Ankle; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Edema; Female; Foot; Humans; Hypertension; Joint Diseases; Male; Middle Aged; Single-Blind Method | 2000 |
Efficacy, tolerability, and impact on quality of life of long-term treatment with manidipine or amlodipine in patients with essential hypertension.
Topics: Adult; Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Chi-Square Distribution; Dihydropyridines; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrobenzenes; Piperazines; Quality of Life; Statistics, Nonparametric | 2001 |
The effects of dihydropyridine and phenylalkylamine calcium antagonist classes on autonomic function in hypertension: the VAMPHYRE study.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Autonomic Nervous System; Baroreflex; Blood Pressure; Calcium Channel Blockers; Carrier Proteins; Cross-Over Studies; Dihydropyridines; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Steroid Isomerases; Treatment Outcome; Verapamil | 2001 |
Cilnidipine more highly attenuates cold pressor stress-induced platelet activation in hypertension than does amlodipine.
Topics: Amlodipine; beta-Thromboglobulin; Blood Pressure; Calcium Channel Blockers; Cold Temperature; Cross-Over Studies; Dihydropyridines; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Platelet Activation; Stress, Physiological; Sympathetic Nervous System | 2001 |
Impact of an ACE inhibitor and calcium antagonist on microalbuminuria and lipid subfractions in type 2 diabetes: a randomised, multi-centre pilot study.
Topics: Aged; Albuminuria; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Apolipoproteins; Apoprotein(a); Benzazepines; Calcium Channel Blockers; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Dihydropyridines; Female; Humans; Lipoprotein(a); Male; Middle Aged; Pilot Projects; Triglycerides | 2002 |
Tolerability of long-term treatment with lercanidipine versus amlodipine and lacidipine in elderly hypertensives.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Male; Peripheral Vascular Diseases; Treatment Outcome | 2002 |
Azelnidipine and amlodipine: a comparison of their pharmacokinetics and effects on ambulatory blood pressure.
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Physicians' Offices | 2003 |
Quantification of leg oedema in postmenopausal hypertensive patients treated with lercanidipine or amlodipine.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Volume; Calcium Channel Blockers; Diastole; Dihydropyridines; Drug Evaluation; Edema; Female; Heart Rate; Humans; Hypertension; Leg; Middle Aged; Norway; Postmenopause; Statistics as Topic; Systole; Time Factors; Treatment Outcome; Women's Health | 2003 |
Heterogeneous effect of calcium antagonists on leg oedema: a comparison of amlodipine versus lercanidipine in hypertensive patients.
Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Edema; Humans; Hypertension; Laser-Doppler Flowmetry; Leg; Male; Middle Aged; Skin; Treatment Outcome; Vasoconstriction | 2003 |
Effects of calcium channel antagonists on left ventricular hypertrophy and diastolic function in patients with essential hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diastole; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine | 2003 |
Comparison between cilnidipine and amlodipine besilate with respect to proteinuria in hypertensive patients with renal diseases.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Calcium Channels, N-Type; Creatinine; Dihydropyridines; Female; Humans; Hypertension, Renal; Logistic Models; Male; Middle Aged; Proteinuria; Treatment Outcome | 2004 |
Effects of the long-acting calcium channel blockers, amlodipine, manidipine and cilnidipine on steroid hormones and insulin resistance in hypertensive obese patients.
Topics: Aged; Amlodipine; Analysis of Variance; Body Mass Index; Calcium Channel Blockers; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Delayed-Action Preparations; Dihydropyridines; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Insulin Resistance; Male; Middle Aged; Nitrobenzenes; Obesity; Piperazines; Probability; Reference Values; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2004 |
Effects of amlodipine and lacidipine on heart rate variability in hypertensive patients with stable angina pectoris and isolated left ventricular diastolic dysfunction.
Topics: Adult; Aged; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dihydropyridines; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Male; Middle Aged; Treatment Outcome; Ventricular Dysfunction, Left | 2005 |
Effect of amlodipine and lacidipine on left ventricular diastolic and long axis functions in arterial hypertension and stable angina pectoris.
Topics: Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Coronary Angiography; Coronary Disease; Diastole; Dihydropyridines; Exercise Test; Female; Humans; Hypertension; Male; Middle Aged; Mitral Valve; Ultrasonography, Doppler; Ventricular Function, Left | 2005 |
Comparison of the effects of cilnidipine and amlodipine on ambulatory blood pressure.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 2005 |
The newly developed calcium antagonist, azelnidipine, increases drain volume in continuous ambulatory peritoneal dialysis patients.
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Creatinine; Cross-Over Studies; Dihydropyridines; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Sympathetic Nervous System; Urine | 2006 |
Randomized study of angiotensin II type 1 receptor blocker vs dihydropiridine calcium antagonist for the treatment of paroxysmal atrial fibrillation in patients with hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension; Secondary Prevention; Tetrazoles | 2006 |
Efficacy of azelnidipine on home blood pressure and pulse rate in patients with essential hypertension: comparison with amlodipine.
Topics: Aged; Amlodipine; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Physicians' Offices | 2006 |
Azelnidipine reduces urinary protein excretion and urinary liver-type fatty acid binding protein in patients with hypertensive chronic kidney disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Amlodipine; Antioxidants; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Deoxyguanosine; Dihydropyridines; Fatty Acid-Binding Proteins; Female; Heart Rate; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Proteinuria | 2007 |
Effects of new calcium channel blocker, azelnidipine, and amlodipine on baroreflex sensitivity and ambulatory blood pressure.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Azetidinecarboxylic Acid; Baroreflex; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies | 2007 |
Antihypertensive efficacy and safety of manidipine versus amlodipine in elderly subjects with isolated systolic hypertension: MAISH study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Dihydropyridines; Diuretics; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; Hypertension; Male; Middle Aged; Nitrobenzenes; Piperazines; Risk Assessment; Risk Factors; Systole; Time Factors; Treatment Outcome | 2007 |
Efonidipine reduces proteinuria and plasma aldosterone in patients with chronic glomerulonephritis.
Topics: Adult; Aged; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Chronic Disease; Cross-Over Studies; Dihydropyridines; Female; Glomerulonephritis; Humans; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds; Proteinuria | 2007 |
Renal and vascular protective effects of cilnidipine in patients with essential hypertension.
Topics: Albuminuria; Amlodipine; Antihypertensive Agents; Arteries; Calcium Channel Blockers; Dihydropyridines; Endothelium, Vascular; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Safety; Vasodilation | 2007 |
Calcium channel blocker, azelnidipine, reduces lipid hydroperoxides in patients with type 2 diabetes independent of blood pressure.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Ascorbic Acid; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Erythrocytes; Female; Humans; Hypertension; Lipid Peroxides; Male; Middle Aged; Organophosphorus Compounds; Pyrenes; Vitamin E | 2007 |
Comparison of the effects of efonidipine and amlodipine on aldosterone in patients with hypertension.
Topics: Aged; Aged, 80 and over; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Nitrophenols; Norepinephrine; Organophosphorus Compounds | 2007 |
Antiproteinuric effect of the calcium channel blocker cilnidipine added to renin-angiotensin inhibition in hypertensive patients with chronic renal disease.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Creatinine; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension, Renal; Male; Middle Aged; Proteinuria; Renal Insufficiency, Chronic; Renin-Angiotensin System; Treatment Outcome | 2007 |
Renal-protective effect of T-and L-type calcium channel blockers in hypertensive patients: an Amlodipine-to-Benidipine Changeover (ABC) study.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Dihydropyridines; Female; Guideline Adherence; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Middle Aged; Proteinuria; Pulse; Renin-Angiotensin System | 2007 |
High doses of lercanidipine are better tolerated than other dihydropyridines in hypertensive patients with metabolic syndrome: results from the TOLERANCE study.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Cross-Sectional Studies; Dihydropyridines; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Nifedipine | 2008 |
Tolerability of high doses of lercanidipine versus high doses of other dihydropyridines in daily clinical practice: the TOLERANCE Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Sectional Studies; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Logistic Models; Male; Middle Aged; Nifedipine; Primary Health Care; Spain; Vasodilation | 2008 |
Add-on manidipine versus amlodipine in diabetic patients with hypertension and microalbuminuria: the AMANDHA study.
Topics: Adult; Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Nitrobenzenes; Piperazines; Prospective Studies; Renin-Angiotensin System | 2008 |
Comparison of the antiproteinuric effects of the calcium channel blockers benidipine and amlodipine administered in combination with angiotensin receptor blockers to hypertensive patients with stage 3-5 chronic kidney disease.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Dihydropyridines; Disease Progression; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Protective Agents; Proteinuria | 2009 |
Long-term effect of efonidipine therapy on plasma aldosterone and left ventricular mass index in patients with essential hypertension.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Natriuretic Peptide, Brain; Nitrophenols; Organophosphorus Compounds; Renin; Time Factors | 2009 |
Manidipine in hypertensive patients with metabolic syndrome: the MARIMBA study.
Topics: Adiponectin; Adult; Aged; Aged, 80 and over; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Nitrobenzenes; Piperazines; Prospective Studies; Single-Blind Method; Tumor Necrosis Factor-alpha | 2009 |
Comparison of the anti-hypertensive effects of the L/N-type calcium channel antagonist cilnidipine, and the L-type calcium channel antagonist amlodipine in hypertensive patients with cerebrovascular disease.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cerebrovascular Disorders; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged | 2009 |
Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Aldosterone; Amlodipine; Arteries; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Deoxyguanosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Female; Glycated Hemoglobin; Humans; Hypertension; Kidney; Lipids; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds | 2009 |
Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo university (ALPS-J).
Topics: Adult; Aged; Amlodipine; Azetidinecarboxylic Acid; Calcium Channel Blockers; Coronary Artery Disease; Dihydropyridines; Disease Progression; Double-Blind Method; Endpoint Determination; Female; Humans; Hypertension; Male; Middle Aged; Ultrasonography; Young Adult | 2009 |
Renoprotective effect of calcium channel blockers in combination with an angiotensin receptor blocker in elderly patients with hypertension. A randomized crossover trial between benidipine and amlodipine.
Topics: Aged; Aged, 80 and over; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Male; Renal Insufficiency, Chronic; Tetrazoles | 2010 |
Comparative effects of benidipine and amlodipine on proteinuria, urinary 8-OHdG, urinary L-FABP, and inflammatory and atherosclerosis markers in early-stage chronic kidney disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Amlodipine; Atherosclerosis; Biomarkers; Calcium Channel Blockers; Deoxyguanosine; Dihydropyridines; Fatty Acid-Binding Proteins; Female; Humans; Inflammation; Kidney Failure, Chronic; Male; Proteinuria | 2010 |
Superior palatability of crushed lercanidipine compared with amlodipine among children.
Topics: Administration, Oral; Amlodipine; Calcium Channel Blockers; Child; Child, Preschool; Dihydropyridines; Female; Humans; Kidney Diseases; Male; Patient Compliance; Patient Satisfaction; Single-Blind Method; Smell; Statistics as Topic; Taste | 2010 |
Effects of efonidipine, an L- and T-type calcium channel blocker, on the renin-angiotensin-aldosterone system in chronic hemodialysis patients.
Topics: Aged; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cross-Over Studies; Dihydropyridines; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds; Renal Dialysis; Renin-Angiotensin System | 2010 |
A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin I; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 2010 |
Antiproteinuric effect of cilnidipine in hypertensive Japanese treated with renin-angiotensin-system inhibitors - a multicenter, open, randomized trial using 24-hour urine collection.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Japan; Male; Proteinuria; Treatment Outcome | 2010 |
Azelnidipine and amlodipine: a comparison of their effects and safety in a randomized double-blinded clinical trial in Chinese essential hypertensive patients.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure Monitoring, Ambulatory; China; Dihydropyridines; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Treatment Outcome | 2010 |
Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Diabetic Nephropathies; Dihydropyridines; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Hypertension; Male; Middle Aged; Nephrosclerosis; Potassium; Severity of Illness Index; Sodium | 2011 |
Effects of manidipine and its combination with an ACE inhibitor on insulin sensitivity and metabolic, inflammatory and prothrombotic markers in hypertensive patients with metabolic syndrome: the MARCADOR study.
Topics: Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biomarkers; Blood Pressure; Dihydropyridines; Drug Combinations; Female; Humans; Hypertension; Insulin Resistance; Lisinopril; Male; Metabolic Syndrome; Middle Aged; Nitrobenzenes; Piperazines; Prospective Studies; Spain; Telmisartan | 2011 |
Comparison of changes of body water measured by using bioelectrical impedance analysis between lercanidipine and amlodipine therapy in hypertensive outpatients.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Body Composition; Body Water; Dihydropyridines; Edema; Electric Impedance; Extracellular Fluid; Female; Humans; Hypertension; Intracellular Fluid; Male; Middle Aged; Outpatients; Prospective Studies; Thailand; Treatment Outcome | 2010 |
Calcium channel blocker inhibition of AGE and RAGE axis limits renal injury in nondiabetic patients with stage I or II chronic kidney disease.
Topics: Adult; Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Calcium Channel Blockers; Chronic Disease; Dihydropyridines; Female; Glycation End Products, Advanced; Humans; Hypertension; Japan; Kidney; Kidney Diseases; Male; Middle Aged; Proteinuria; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Time Factors; Treatment Outcome | 2011 |
Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo University (ALPS-J).
Topics: Amlodipine; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Coronary Artery Disease; Dihydropyridines; Humans; Hypertension; Lipids; Plaque, Atherosclerotic; Ultrasonography, Interventional | 2011 |
Design and rationale of Japanese evaluation between Formula of Azelnidipine and amlodipine add on olmesartan to Get antialbuminuric effect study (J-FLAG) : evaluation of the antialbuminuric effects between calcium channel blocker with sympatholytic action
Topics: Adult; Aged; Albuminuria; Amlodipine; Azetidinecarboxylic Acid; Calcium Channel Blockers; Diabetic Nephropathies; Dihydropyridines; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Middle Aged; Research Design; Sympatholytics; Tetrazoles | 2011 |
Design and rationale of the study of assessment for kidney function by urinary microalbumin in randomized (SAKURA) trial.
Topics: Aged; Albuminuria; Amlodipine; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Clinical Protocols; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Female; Humans; Hypertension; Kidney Function Tests; Male; Middle Aged; Renin-Angiotensin System | 2011 |
Effects of Azelnidipine plus OlmesaRTAn versus amlodipine plus olmesartan on central blood pressure and left ventricular mass index: the AORTA study.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Ultrasonography | 2011 |
Effects of calcium channel blockers on glucose tolerance, inflammatory state, and circulating progenitor cells in non-diabetic patients with essential hypertension: a comparative study between azelnidipine and amlodipine on glucose tolerance and endotheli
Topics: Adult; Aged; Amlodipine; Azetidinecarboxylic Acid; Blood Glucose; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation; Male; Middle Aged; Prospective Studies; Stem Cells | 2011 |
Efficacy and safety of aranidipine enteric-coated tablets compared with amlodipine in Chinese patients with mild to moderate essential hypertension: a multicenter, randomized, double-blind, parallel-controlled clinical trial.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Tablets, Enteric-Coated | 2012 |
Angiotensin II receptor blocker-based therapy in Japanese elderly, high-risk, hypertensive patients.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Japan; Male; Prospective Studies; Single-Blind Method; Survival Analysis; Tetrazoles; Treatment Outcome | 2012 |
Long-term effects of calcium antagonists on augmentation index in hypertensive patients with chronic kidney disease: a randomized controlled study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic; Time | 2012 |
The combination of OLmesartan and a CAlcium channel blocker (azelnidipine) or candesartan and a calcium channel blocker (amlodipine) in type 2 diabetic hypertensive patients: the OLCA study.
Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Therapy, Combination; Female; Glycated Hemoglobin; Heart Rate; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome | 2012 |
L/T-type and L/N-type calcium-channel blockers attenuate cardiac sympathetic nerve activity in patients with hypertension.
Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cross-Over Studies; Dihydropyridines; Female; Heart; Heart Conduction System; Hemodynamics; Humans; Hypertension; Male; Nitrophenols; Norepinephrine; Organophosphorus Compounds; Prospective Studies; Sympathetic Nervous System | 2012 |
Renoprotective and antioxidant effects of cilnidipine in hypertensive patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Antioxidants; Blood Pressure; Calcium Channel Blockers; Deoxyguanosine; Dihydropyridines; Fatty Acid-Binding Proteins; Female; Heart Rate; Humans; Hypertension; Incidence; Male; Middle Aged; Oxidative Stress; Prospective Studies; Renal Insufficiency, Chronic | 2012 |
L/N-type calcium channel blocker cilnidipine reduces plasma aldosterone, albuminuria, and urinary liver-type fatty acid binding protein in patients with chronic kidney disease.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Creatinine; Dihydropyridines; Down-Regulation; Fatty Acid-Binding Proteins; Female; Humans; Hypertension; Japan; Linear Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Renal Insufficiency, Chronic; Time Factors; Treatment Outcome | 2013 |
[Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo Medical University].
Topics: Aged; Amlodipine; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Coronary Artery Disease; Dihydropyridines; Female; Humans; Hypertension; Male; Percutaneous Coronary Intervention; Plaque, Atherosclerotic; Preoperative Period; Prospective Studies; Ultrasonography, Interventional | 2012 |
Effects of manidipine vs. amlodipine on intrarenal haemodynamics in patients with arterial hypertension.
Topics: Adult; Aged; Albuminuria; Amlodipine; Creatinine; Dihydropyridines; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Nitrobenzenes; Piperazines | 2013 |
Azelnidipine plus olmesartan versus amlodipine plus olmesartan on arterial stiffness and cardiac function in hypertensive patients: a randomized trial.
Topics: Aged; Amlodipine; Azetidinecarboxylic Acid; Diastole; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Pulse Wave Analysis; Tetrazoles; Vascular Stiffness; Ventricular Function, Left | 2013 |
Comparison of the antialbuminuric effects of L-/N-type and L-type calcium channel blockers in hypertensive patients with diabetes and microalbuminuria: the study of assessment for kidney function by urinary microalbumin in randomized (SAKURA) trial.
Topics: Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System | 2013 |
Sex differences in response to angiotensin II receptor blocker-based therapy in elderly, high-risk, hypertensive Japanese patients: a subanalysis of the OSCAR study.
Topics: Age Factors; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Asian People; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Imidazoles; Japan; Male; Prospective Studies; Risk Factors; Sex Factors; Tetrazoles; Treatment Outcome | 2014 |
Impact of azelnidipine and amlodipine on left ventricular mass and longitudinal function in hypertensive patients with left ventricular hypertrophy.
Topics: Adult; Aged; Amlodipine; Analysis of Variance; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Drug Administration Schedule; Echocardiography, Doppler, Pulsed; Female; Follow-Up Studies; Humans; Hypertension; Hypertrophy, Left Ventricular; Image Interpretation, Computer-Assisted; Male; Middle Aged; Prospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2014 |
Differential effects of azelnidipine and amlodipine on sympathetic nerve activity in patients with primary hypertension.
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Baroreflex; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Essential Hypertension; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sympathetic Nervous System | 2014 |
Comparison of the antialbuminuric effects of benidipine and hydrochlorothiazide in Renin-Angiotensin System (RAS) inhibitor-treated hypertensive patients with albuminuria: the COSMO-CKD (COmbination Strategy on Renal Function of Benidipine or Diuretics Tr
Topics: Adult; Aged; Albuminuria; Amlodipine; Blood Pressure; Dihydropyridines; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2014 |
Effects of the N/L-type calcium channel blocker cilnidipine on nephropathy and uric acid metabolism in hypertensive patients with chronic kidney disease (J-CIRCLE study).
Topics: Aged; Aged, 80 and over; Albuminuria; Amlodipine; Blood Pressure; Calcium Channel Blockers; Creatinine; Cross-Over Studies; Diabetic Nephropathies; Dihydropyridines; Dose-Response Relationship, Drug; Drug Substitution; Female; Humans; Hypertension, Renal; Japan; Kidney Failure, Chronic; Male; Middle Aged; Nephrosclerosis; Uric Acid | 2014 |
Effects of lercanidipine versus amlodipine in hypertensive patients with cerebral ischemic stroke.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Brain Ischemia; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged; Stroke; Treatment Outcome | 2015 |
Long-term effects of L- and N-type calcium channel blocker on uric acid levels and left atrial volume in hypertensive patients.
Topics: Amlodipine; Atrial Function, Left; Atrial Remodeling; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; China; Diastole; Dihydropyridines; Down-Regulation; Echocardiography, Doppler; Female; Humans; Hypertension; Hyperuricemia; Male; Middle Aged; Time Factors; Treatment Outcome; Uric Acid; Ventricular Dysfunction, Left; Ventricular Function, Left | 2016 |
Lercanidipine valuable effect on urine protein losses: the RED LEVEL study.
Topics: Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Prospective Studies | 2016 |
Differential effects of lercanidipine/enalapril versus amlodipine/enalapril and hydrochlorothiazide/enalapril on target organ damage and sympathetic activation in non-obese essential hypertensive subjects.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Middle Aged; Sympathetic Nervous System; Vascular Stiffness | 2016 |
Factors associated with the reduction of albumin excretion in diabetic hypertensive patients: differential effect of manidipine versus amlodipine.
Topics: Adult; Aged; Albumins; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Nitrobenzenes; Piperazines | 2017 |
Reduction in microalbuminuria by calcium channel blockers in patients with type 2 diabetes mellitus and hypertension-A randomized, open-label, active-controlled, superiority, parallel-group clinical trial.
Topics: Adult; Aged; Albuminuria; Amlodipine; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Treatment Outcome | 2017 |
Effect of amlodipine, efonidipine, and trichlormethiazide on home blood pressure and upper-normal microalbuminuria assessed by casual spot urine test in essential hypertensive patients.
Topics: Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Irbesartan; Male; Middle Aged; Nitrophenols; Organophosphorus Compounds; Tetrazoles; Trichlormethiazide; Urinalysis | 2018 |
A Randomized Open-Label Parallel-Group Study Comparing the Efficacy and Safety of Cilnidipine and Amlodipine in Hypertensive Adults.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension; India | 2022 |
137 other study(ies) available for amlodipine and dihydropyridines
| Article | Year |
|---|---|
[Amlodipine: pharmacokinetic and pharmacodynamic profile of a calcium antagonist with prolonged effect].
Topics: Amlodipine; Angina Pectoris; Animals; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Humans; Nifedipine; Structure-Activity Relationship | 1992 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
Block of L-type calcium channels by charged dihydropyridines. Sensitivity to side of application and calcium.
Topics: Amlodipine; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Diffusion; Dihydropyridines; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Myocardium; Nifedipine; Nisoldipine; Receptors, Nicotinic | 1991 |
A molecular model involving the membrane bilayer in the binding of lipid soluble drugs to their receptors in heart and brain.
Topics: 1,2-Dipalmitoylphosphatidylcholine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Brain; Cholesterol; Dihydropyridines; Gels; Lipid Bilayers; Membranes; Models, Chemical; Models, Molecular; Myocardium; Nifedipine; Rats; Receptors, Drug; Sarcolemma; Solubility | 1990 |
The effects of dihydropyridine calcium channel modulators on pentylenetetrazole convulsions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Male; Mice; Nifedipine; Nimodipine; Seizures | 1990 |
The hemodynamic effects of lacidipine in anesthetized dogs: comparison with nitrendipine, amlodipine, verapamil, and diltiazem.
Topics: Amlodipine; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Stroke Volume; Vascular Resistance; Verapamil | 1991 |
Biotransformation of amlodipine. Identification and synthesis of metabolites found in rat, dog and human urine/confirmation of structures by gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry.
Topics: Amlodipine; Animals; Biotransformation; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dihydropyridines; Dogs; Gas Chromatography-Mass Spectrometry; Humans; Nifedipine; Rats; Species Specificity | 1989 |
Amlodipine, a new 1,4-dihydropyridine calcium antagonist with a particularly strong antihypertensive profile.
Topics: Amlodipine; Animals; Antihypertensive Agents; Arteriosclerosis; Calcium; Calcium Channel Blockers; Dihydropyridines; Heart; In Vitro Techniques; Isoproterenol; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocardium; Nifedipine; Rabbits; Rats; Retinal Artery; Swine; Vasoconstriction | 1989 |
Relaxation of potassium chloride-induced contractions by amlodipine and its interaction with the 1,4-dihydropyridine-binding site in pig coronary artery.
Topics: Amlodipine; Animals; Binding Sites; Calcium Channel Blockers; Coronary Vessels; Dihydropyridines; Isradipine; Nifedipine; Oxadiazoles; Potassium Chloride; Sarcolemma; Stereoisomerism; Swine; Vasoconstriction; Vasodilation | 1989 |
Modulation of calcium channels by charged and neutral dihydropyridines.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electric Conductivity; Electrochemistry; Hydrogen-Ion Concentration; Ions; Membrane Potentials; Nifedipine; Protons | 1989 |
Long-acting dihydropyridine calcium antagonists. 1. 2-Alkoxymethyl derivatives incorporating basic substituents.
Topics: Amlodipine; Animals; Biological Assay; Biological Availability; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Dogs; Guinea Pigs; Hemodynamics; Kinetics; Male; Nifedipine; Pyridines; Rats; Vasoconstriction | 1986 |
Residual inhibition in density of [3H]isradipine binding sites in rat brain membrane pretreated with amlodipine.
Topics: Amlodipine; Animals; Binding Sites; Brain; Calcium Channel Blockers; Dihydropyridines; Isradipine; Male; Nifedipine; Oxadiazoles; Radioligand Assay; Rats; Rats, Wistar | 1995 |
Cardiovascular effects of benidipine and amlodipine in isolated tissues and anesthetized dogs.
Topics: Amlodipine; Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Vessels; Dihydropyridines; Dogs; Electric Stimulation; Female; Heart; In Vitro Techniques; Injections, Intravenous; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Papillary Muscles | 1994 |
Vascular versus myocardial selectivity of dihydropyridine calcium antagonists as studied in vivo and in vitro.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Felodipine; Heart; Heart Rate; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Organ Specificity; Rats; Rats, Inbred SHR | 1995 |
Inhibition of cardiac L-type calcium channels by quaternary amlodipine: implications for pharmacokinetics and access to dihydropyridine binding site.
Topics: Amlodipine; Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Guinea Pigs; Heart Ventricles; Humans; Isradipine; Kinetics; Membrane Potentials; Muscle, Skeletal; Myocardium; Rabbits | 1995 |
Vascular reactivity: a measurement of calcium channel blockade.
Topics: Amlodipine; Angiotensin II; Blood Pressure; Dihydropyridines; Humans; Infusions, Intravenous; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Vasoconstriction | 1995 |
Probing membrane bilayer interactions of 1,4-dihydropyridine calcium channel blockers. Implications for aging and Alzheimer's disease.
Topics: Aged; Aging; Alzheimer Disease; Amlodipine; Brain Chemistry; Calcium Channel Blockers; Cell Membrane; Cholesterol; Dihydropyridines; Female; Humans; In Vitro Techniques; Lipid Bilayers; Male; Membrane Lipids; Membrane Proteins; Nerve Tissue Proteins; Neurons; Parkinson Disease; Phospholipids; Solubility; X-Ray Diffraction | 1994 |
In vitro antioxidant activity of calcium antagonists against LDL oxidation compared with alpha-tocopherol.
Topics: Adult; Amlodipine; Antioxidants; Calcium Channel Blockers; Copper; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Humans; Isradipine; Lipoproteins, LDL; Oxidation-Reduction; Reference Values; Thiobarbituric Acid Reactive Substances; Verapamil; Vitamin E | 1994 |
Quantification of the calcium antagonism of lacidipine by kinetic analysis.
Topics: Amlodipine; Animals; Binding Sites; Body Fluid Compartments; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Male; Mathematical Computing; Models, Biological; Muscle Proteins; Rabbits | 1994 |
Hemodynamic and electrophysiologic effects of first- and second-generation calcium antagonists.
Topics: Amlodipine; Calcium Channel Blockers; Cardiac Output; Dihydropyridines; Electrophysiology; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Myocardial Contraction; Myocardial Ischemia; Ventricular Function, Left | 1994 |
Ca2+ channel blocking activity of lacidipine and amlodipine in A7r5 vascular smooth muscle cells.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cytosol; Dihydropyridines; Female; Fura-2; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Pregnancy; Rats; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1993 |
Ca(2+)-channel blockers modulate the expression of interleukin-6 and interleukin-8 genes in human vascular smooth muscle cells.
Topics: Adrenergic beta-Antagonists; Amlodipine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Diuretics; Felodipine; Fibroblasts; Furosemide; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Isradipine; Lung; Muscle Proteins; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Propranolol; Transcription, Genetic | 1995 |
Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix.
Topics: Amlodipine; Becaplermin; Calcium Channel Blockers; Cells, Cultured; Collagen; Collagenases; Dihydropyridines; Diltiazem; Enzyme Activation; Extracellular Matrix; Felodipine; Fibroblasts; Humans; Kinetics; Lung; Metalloendopeptidases; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Platelet-Derived Growth Factor; Procollagen; Proline; Proto-Oncogene Proteins c-sis; Transcription, Genetic; Verapamil | 1996 |
Enantiomer separation of dihydropyridine calcium antagonists with cyclodextrins as chiral selectors: structural correlation.
Topics: Amlodipine; Buffers; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cyclodextrins; Dihydropyridines; Electrolytes; Electrophoresis, Capillary; Isradipine; Microspheres; Molecular Conformation; Nimodipine; Nisoldipine; Nitrendipine; Sodium Dodecyl Sulfate; Solvents; Stereoisomerism; Surface-Active Agents | 1996 |
Effects of benidipine, a long-acting calcium antagonist, on renal functions in anaesthetized spontaneously hypertensive rats.
Topics: Amlodipine; Anesthesia; Animals; Calcium Channel Blockers; Dihydropyridines; Diuresis; Kidney; Kidney Function Tests; Lithium; Male; Natriuresis; Rats; Rats, Inbred SHR | 1995 |
Venodilator effects of pranidipine, a 1,4-dihydropyridine Ca2+ channel antagonist, in rats: comparison with nifedipine and amlodipine.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Dihydropyridines; Injections, Intravenous; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Venous Pressure | 1997 |
Synthesis of two optically active calcium channel antagonists labelled with carbon-11 for in vivo cardiac PET imaging.
Topics: Amlodipine; Animals; Binding, Competitive; Calcium Channel Blockers; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dihydropyridines; Dogs; Heart; Heart Diseases; Isotope Labeling; Isradipine; Magnetic Resonance Spectroscopy; Muscle, Smooth, Vascular; Myocardium; Reproducibility of Results; Stereoisomerism; Tomography, Emission-Computed | 1997 |
Molecular pharmacology of UK-118, 434-05, a permanently charged amlodipine analog.
Topics: Amlodipine; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Gene Expression; Humans; Kidney; Membrane Potentials; Muscle, Smooth, Vascular; Myocardium; Structure-Activity Relationship | 1997 |
Catalepsy induced by calcium channel blockers in mice.
Topics: Amlodipine; Animals; Binding, Competitive; Calcium Channel Blockers; Catalepsy; Dihydropyridines; Diltiazem; Disease Models, Animal; Flunarizine; Male; Mice; Muscarinic Antagonists; Nitrobenzenes; Piperazines; Predictive Value of Tests; Receptors, Cholinergic; Receptors, Dopamine D1; Receptors, Dopamine D2; Scopolamine; Time Factors; Verapamil | 1998 |
Pranidipine, a new 1,4-dihydropyridine calcium channel blocker, enhances cyclic GMP-independent nitric oxide-induced relaxation of the rat aorta.
Topics: Amlodipine; Animals; Aorta; Calcium Channel Blockers; Cyclic GMP; Dihydropyridines; Dimethyl Sulfoxide; Dinoprost; Endothelium, Vascular; Indomethacin; Male; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 1998 |
Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system.
Topics: Acetylcholine; Acridines; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteriosclerosis; Diet, Atherogenic; Dihydropyridines; Electron Spin Resonance Spectroscopy; Hypercholesterolemia; Lipids; Luminescent Measurements; Macrophages; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Phenylephrine; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, LDL; Renin-Angiotensin System; Superoxides; Tetrazoles; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1999 |
[Effects of benidipine hydrochloride (Coniel) on blood pressure, heart rate and plasma norepinephrine concentration in spontaneously hypertensive rats].
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Heart Rate; Hypertension; Male; Nifedipine; Norepinephrine; Rats; Rats, Inbred SHR | 1999 |
Resolution of newly synthesized racemic dihydropyridines with different chiral selectors by means of capillary electrophoresis.
Topics: Amlodipine; Calcium Channel Blockers; Cyclodextrins; Dihydropyridines; Electrophoresis, Capillary; Nicardipine; Stereoisomerism | 1999 |
Pranidipine enhances the action of nitric oxide released from endothelial cells.
Topics: Amlodipine; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cells, Cultured; Coculture Techniques; Cyclic GMP; Dihydropyridines; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Male; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Superoxide Dismutase | 2000 |
Modulation of tumor necrosis factor-alpha production with anti-hypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Diuretics; Doxazosin; Humans; Hydrochlorothiazide; Interleukin-1; Interleukin-6; Lipopolysaccharides; Male; Metoprolol; Mice; Mice, Inbred BALB C; Monocytes; Nicardipine; Nitrobenzenes; Piperazines; Sodium Chloride Symporter Inhibitors; Tumor Necrosis Factor-alpha | 2000 |
Pharmacodynamic interaction between mibefradil and other calcium channel blockers.
Topics: Amlodipine; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Cell Membrane; Dihydropyridines; Drug Interactions; Ethosuximide; Female; Gallopamil; Humans; In Vitro Techniques; Isradipine; Male; Mibefradil; Myocardial Contraction; Perfusion; Radioligand Assay; Rats; Rats, Wistar; Ventricular Pressure | 2000 |
Improvement in the histopathology of hearts from cardiomyopathic BIO TO-2 hamsters following long-term administration of amlodipine and cilnidipine.
Topics: Amlodipine; Animals; Animals, Inbred Strains; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiomyopathies; Cricetinae; Dihydropyridines; Heart; Kinetics; Male; Mesocricetus; Myocardium; Organ Size | 2000 |
Effects of long-term treatment with calcium antagonists on periarterial nerve function in the mesenteric artery of spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Hypertension; Male; Mesenteric Arteries; Nervous System; Nicardipine; Norepinephrine; Rats; Rats, Inbred SHR; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Mechanism of action of angiotensin II in human isolated subcutaneous resistance arteries.
Topics: Amlodipine; Angiotensin II; Arteries; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Flavonoids; Genistein; Humans; In Vitro Techniques; Nickel; Norepinephrine; Potassium; Ryanodine; Skin; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Effects of amlodipine and lacidipine on cardiac remodelling and renin production in salt-loaded stroke-prone hypertensive rats.
Topics: Actins; Amlodipine; Animals; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Collagen Type I; Dihydropyridines; Dose-Response Relationship, Drug; Fibrosis; Gene Expression Regulation; Heart Ventricles; Hypertension; Hypertrophy; Kidney; Male; Muscle, Skeletal; Rats; Rats, Inbred SHR; Renin; RNA, Messenger; Sodium Chloride, Dietary; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
The use of cyclodextrin-modified capillary electrophoresis in the determination of the enantiomeric purity.
Topics: Amlodipine; Cyclodextrins; Dihydropyridines; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Stereoisomerism | 2002 |
In vivo receptor binding of benidipine and amlodipine in mesenteric arteries and other tissues of spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Area Under Curve; Blood Proteins; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebral Cortex; Dihydropyridines; Drug Interactions; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocardium; Nifedipine; Protein Binding; Rats; Rats, Inbred SHR; Tissue Distribution | 2002 |
Cyclosporin enhances the tendency towards oedema and flushing noted on dihydropyridine calcium channel blockers.
Topics: Adolescent; Adult; Amlodipine; Calcium Channel Blockers; Child; Child, Preschool; Cyclosporine; Dihydropyridines; Edema; Female; Flushing; Humans; Hypertension; Infant; Male | 2002 |
Dihydropyridines are not substitutable without careful monitoring.
Topics: Adverse Drug Reaction Reporting Systems; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Felodipine; Humans; Nifedipine | 2002 |
[Pharmaceutical chemistry of "dipines"].
Topics: Amlodipine; Calcium Channel Blockers; Dihydropyridines; Molecular Structure; Nifedipine; Nimodipine; Structure-Activity Relationship | 2002 |
Emerging data on calcium-channel blockers: the COHORT study.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 2003 |
Long-acting Ca2+ blockers prevent myocardial remodeling induced by chronic NO inhibition in rats.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Dihydropyridines; Enzyme Inhibitors; Heart Rate; Heart Ventricles; Kinetics; Male; Mitogen-Activated Protein Kinases; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases, 70-kDa | 2003 |
Antioxidant activity of different dihydropyridines.
Topics: Amlodipine; Animals; Antioxidants; Cattle; Cells, Cultured; Dihydropyridines; Endothelium, Vascular; Fluoresceins; Humans; Lipoproteins, LDL; Molecular Structure; Nifedipine; Nimodipine; Reactive Oxygen Species | 2003 |
Enantiomeric separation by HPLC of 1,4-dihydropyridines with vancomycin as chiral selector.
Topics: Amlodipine; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dihydropyridines; Models, Molecular; Molecular Conformation; Stereoisomerism; Vancomycin | 2003 |
Protective effect of benidipine against sodium azide-induced cell death in cultured neonatal rat cardiac myocytes.
Topics: Adenosine Triphosphate; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Cell Death; Cells, Cultured; Cysteine Proteinase Inhibitors; Dihydropyridines; Dipeptides; Dose-Response Relationship, Drug; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria, Muscle; Myocytes, Cardiac; Nifedipine; Rats; Rats, Sprague-Dawley; Sodium Azide; Tetrazoles | 2003 |
Azelnidipine, a newly developed long-acting calcium antagonist, inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endothelial cells through its anti-oxidative properties.
Topics: Amlodipine; Antioxidants; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Endothelium, Vascular; Humans; In Vitro Techniques; Interleukin-8; Radioligand Assay; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Umbilical Veins | 2004 |
Changing characteristics of patients with vasospastic angina in the era of new calcium channel blockers.
Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris, Variant; Calcium Channel Blockers; Cohort Studies; Diabetes Complications; Dihydropyridines; Female; Humans; Hyperlipidemias; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Prognosis; Smoking; Survival Rate; Vasodilator Agents | 2004 |
The N- and L-type calcium channel blocker cilnidipine suppresses renal injury in dahl rats fed a high-sucrose diet, an experimental model of metabolic syndrome.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dietary Sucrose; Dihydropyridines; Disease Models, Animal; Hypertension, Renal; Kidney Diseases; Male; Metabolic Syndrome; Rats; Rats, Inbred Dahl; Treatment Outcome | 2005 |
Increased vascular selectivity and prolonged pharmacological efficacy of the L-type Ca2+ channel antagonist lercanidipine in human cardiovascular tissue.
Topics: Adolescent; Adult; Aged; Amlodipine; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Female; Humans; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Myocardial Contraction; Nifedipine; Protein Binding; Stimulation, Chemical; Vasodilation | 2005 |
Calcium channel blockades exhibit anti-inflammatory and antioxidative effects by augmentation of endothelial nitric oxide synthase and the inhibition of angiotensin converting enzyme in the N(G)-nitro-L-arginine methyl ester-induced hypertensive rat aorta
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Aorta; Blood Pressure; Body Weight; Calcium Channel Blockers; Chemokine CCL2; Dihydropyridines; Enzyme Inhibitors; Gene Expression Regulation; Heart Rate; Hypertension; Inflammation; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitrobenzenes; Oxidative Stress; Peptidyl-Dipeptidase A; Piperazines; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Vascular Cell Adhesion Molecule-1 | 2005 |
Comparative effects of pranidipine with amlodipine in rats with heart failure.
Topics: Administration, Oral; Amlodipine; Animals; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Calcium-Transporting ATPases; Cardiac Myosins; Dihydropyridines; Dose-Response Relationship, Drug; Echocardiography; Fibrosis; Heart Failure; Heart Rate; Male; Myocarditis; Myocardium; Nitric Oxide Synthase Type II; Rats; Rats, Inbred Lew; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Survival Rate; Time Factors; Ventricular Function, Left | 2006 |
Effects of a new calcium channel blocker, azelnidipine, on systemic hemodynamics and renal sympathetic nerve activity in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Azetidinecarboxylic Acid; Baroreflex; Calcium Channel Blockers; Dihydropyridines; Hemodynamics; Kidney; Male; Nitroprusside; Phenylephrine; Rats; Rats, Inbred SHR; Sympathetic Nervous System; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis.
Topics: Amlodipine; Animals; Azetidinecarboxylic Acid; Cardiomegaly; Dihydropyridines; Endomyocardial Fibrosis; Hydralazine; Hypertension; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tachycardia; Ventricular Remodeling | 2006 |
Effects of benidipine, a long-lasting dihydropyridine-Ca2+ channel blocker, on cerebral blood flow autoregulation in spontaneously hypertensive rats.
Topics: Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Carbon Dioxide; Cerebral Cortex; Dihydropyridines; Hypertension; Male; Oxygen; Rats; Rats, Inbred SHR; Rats, Wistar; Species Specificity; Tetrazoles; Ultrasonography, Doppler, Pulsed; Vascular Resistance | 2006 |
Effects of benidipine in a rat model for experimental angina.
Topics: Amlodipine; Angina Pectoris; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Male; Nifedipine; Nitrophenols; Organophosphorus Compounds; Rats; Rats, Inbred Strains | 2006 |
G1 cell cycle arrest by amlodipine, a dihydropyridine Ca2+ channel blocker, in human epidermoid carcinoma A431 cells.
Topics: Amlodipine; Calcium Channel Blockers; Carcinoma, Squamous Cell; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinases; Dihydropyridines; G1 Phase; Humans; Nuclear Proteins; Phosphorylation; Repressor Proteins; Tumor Cells, Cultured | 2007 |
Prevention of neuronal damage by calcium channel blockers with antioxidative effects after transient focal ischemia in rats.
Topics: Amlodipine; Animals; Antioxidants; Apoptosis; Azetidinecarboxylic Acid; Brain; Brain Edema; Brain Infarction; Calcium Channel Blockers; Dihydropyridines; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Inbred WKY; Reperfusion Injury; Treatment Outcome | 2007 |
Protective effects of amlodipine and lacidipine on ovariectomy-induced bone loss in rats.
Topics: Amlodipine; Animals; Bone and Bones; Calcium; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Femur; Osteoporosis; Ovariectomy; Phosphorus; Rats; Rats, Wistar; Spectrometry, X-Ray Emission | 2008 |
Oral Therapy with Amlodipine and Lacidipine, 1,4-Dihydropyridine Derivatives Showing Activity against Experimental Visceral Leishmaniasis.
Topics: Administration, Oral; Amlodipine; Animals; Antiprotozoal Agents; Dihydropyridines; Leishmania donovani; Leishmaniasis, Visceral; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Treatment Outcome | 2008 |
Effects of benidipine and some other calcium channel blockers on the prognosis of patients with vasospastic angina. Cohort study with evaluation of the ergonovine coronary spasm induction test.
Topics: Adult; Aged; Aging; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cohort Studies; Coronary Angiography; Coronary Stenosis; Coronary Vasospasm; Diabetes Complications; Dihydropyridines; Diltiazem; Ergonovine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifedipine; Oxytocics; Prognosis; Risk Factors | 2007 |
Compliance with antihypertensive therapy in the elderly: a comparison of fixed-dose combination amlodipine/benazepril versus component-based free-combination therapy.
Topics: Age Factors; Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Cohort Studies; Dihydropyridines; Drug Combinations; Drug Therapy, Combination; Female; Health Care Costs; Humans; Hypertension; Longitudinal Studies; Male; Medicaid; Patient Compliance; Retrospective Studies; South Carolina; United States | 2008 |
Prognostic effects of benidipine in patients with vasospastic angina: comparison with diltiazem and amlodipine.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Diseases; Cohort Studies; Coronary Vasospasm; Dihydropyridines; Diltiazem; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Prognosis; Retrospective Studies; Risk Factors | 2008 |
Effects of calcium channel blockers on hyaluronidase-induced capillary vascular permeability.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Capillary Permeability; Carrageenan; Dihydropyridines; Hyaluronoglucosaminidase; Inflammation; Injections, Intravenous; Male; Nicardipine; Rats; Rats, Wistar | 2008 |
Prevention of vascular injury by combination of an AT1 receptor blocker, olmesartan, with various calcium antagonists.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Chemokine CCL2; Dihydropyridines; Drug Synergism; Femoral Artery; Imidazoles; Ligation; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Neuropeptides; Nifedipine; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Superoxides; Tetrazoles; Tumor Necrosis Factor-alpha; Tunica Intima | 2009 |
Histological protection by cilnidipine, a dual L/N-type Ca(2+) channel blocker, against neurotoxicity induced by ischemia-reperfusion in rat retina.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Drug Evaluation, Preclinical; In Situ Nick-End Labeling; Injections; Injections, Intravenous; Male; N-Methylaspartate; Neuroprotective Agents; Nitroso Compounds; omega-Conotoxins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Retinal Degeneration; Retinal Diseases; Vitreous Body | 2009 |
Chronotropic effects of azelnidipine, a slow- and long-acting dihydropyridine-type calcium channel blocker, in anesthetized dogs: a comparison with amlodipine.
Topics: Adjuvants, Anesthesia; Amlodipine; Anesthesia; Animals; Atropine; Azetidinecarboxylic Acid; Baroreflex; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Coronary Vessels; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Heart Rate; Infusions, Intravenous; Injections, Intravenous; Pentobarbital; Perfusion; Propranolol; Sympathetic Nervous System; Time Factors | 2009 |
Different effects of L/N-type and L-type calcium channel blockers on the renin-angiotensin-aldosterone system in SHR/Izm.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Conotoxins; Dihydropyridines; Humans; Male; Norepinephrine; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Time Factors | 2009 |
Comparison of antioxidant activity of cilnidipine and amlodipine.
Topics: Amlodipine; Antioxidants; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Mesangial Cells; Superoxides | 2009 |
Long-term blockade of L/N-type Ca(2+) channels by cilnidipine ameliorates repolarization abnormality of the canine hypertrophied heart.
Topics: Action Potentials; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrioventricular Block; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cardiomegaly; Chronic Disease; Dihydropyridines; Dogs; Electrocardiography; Epinephrine; Female; Male; Neurotransmitter Agents; Norepinephrine; Tetrazoles; Time Factors | 2009 |
Effects of benidipine, a long-acting T-type calcium channel blocker, on home blood pressure and renal function in patients with essential hypertension: a retrospective, 'real-world' comparison with amlodipine.
Topics: Adult; Aged; Albuminuria; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium Channels, T-Type; Dihydropyridines; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Retrospective Studies | 2009 |
Cardiovascular effects of azelnidipine in comparison with those of amlodipine assessed in the halothane-anaesthetized dog.
Topics: Amlodipine; Anesthetics, Inhalation; Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Female; Halothane; Heart Rate; Heart Ventricles; Infusions, Intravenous; Male; Myocardial Contraction; Norepinephrine | 2010 |
A region of N-type Ca(2+) channel critical for blockade by the dihydropyridine amlodipine.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amlodipine; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Dose-Response Relationship, Drug; Electrophysiology; Female; Lysine; Microelectrodes; Oocytes; Patch-Clamp Techniques; Xenopus | 2010 |
Effects of combination therapy with angiotensin II type I receptor blockers and calcium channel blockers on renal function in hypertensive patients/a retrospective, "real-world" comparative study.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Creatinine; Dihydropyridines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hypertension; Kaplan-Meier Estimate; Kidney; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Nifedipine; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Treatment Outcome | 2010 |
Beneficial effects of L- and N-type calcium channel blocker on glucose and lipid metabolism and renal function in patients with hypertension and type II diabetes mellitus.
Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Diabetes Mellitus, Type 2; Dihydropyridines; Female; Glucose; Humans; Hypertension; Kidney; Lipid Metabolism; Male; Middle Aged | 2011 |
Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: possible involvement of N-type calcium channel in podocyte.
Topics: Amlodipine; Animals; Base Sequence; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Calcium Channels, N-Type; Creatinine; Dihydropyridines; Disease Models, Animal; DNA Primers; Humans; Kidney; Male; Metabolic Syndrome; Oxidative Stress; Podocytes; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger; RNA, Small Interfering; Triglycerides | 2010 |
[Antihypertrophic effect of dihydropyridines calcium channel blockers is dependent on their potential of blocking N-type calcium channel].
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cardiomegaly; Dihydropyridines; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Nifedipine | 2010 |
L-type calcium channel blockers and Parkinson disease in Denmark.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Community Health Planning; Denmark; Dihydropyridines; Female; Humans; Logistic Models; Male; Middle Aged; Outpatients; Parkinson Disease; Prescription Drugs; Registries; Retrospective Studies | 2010 |
Combination therapy with irbesartan and efonidipine for attenuation of proteinuria in Dahl salt-sensitive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Chemokine CCL2; Collagen Type I; Dihydropyridines; Drug Therapy, Combination; Gene Expression; Glomerulosclerosis, Focal Segmental; Hypertension; Irbesartan; Kidney Glomerulus; Male; NADPH Oxidases; Nitrophenols; Organophosphorus Compounds; Proteinuria; Rats; Rats, Inbred Dahl; Tetrazoles; Transforming Growth Factor beta | 2010 |
The N-type and L-type calcium channel blocker cilnidipine suppresses renal injury in Dahl rats fed a high-salt diet.
Topics: Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Glomerulonephritis; Hypertension; Kidney; Kidney Diseases; Male; Organ Size; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Time Factors; Valine; Valsartan | 2010 |
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Topics: Amlodipine; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Body Weight; Calcium Channel Blockers; Dihydropyridines; Down-Regulation; Gelatinases; Hypertension, Renovascular; Hypertrophy; Lipid Peroxides; Male; Matrix Metalloproteinase 2; Nifedipine; Nimodipine; Rats; Rats, Wistar; Reactive Oxygen Species; Tunica Media | 2011 |
Effects of eplerenone on nephrotic syndrome in a patient with renovascular hypertension.
Topics: Amlodipine; Antihypertensive Agents; Dihydropyridines; Eplerenone; Humans; Hypertension, Renovascular; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Nephrotic Syndrome; Proteinuria; Radiography; Spironolactone; Treatment Outcome | 2011 |
L/N-type calcium channel blocker cilnidipine ameliorates proteinuria and inhibits the renal renin-angiotensin-aldosterone system in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Collagen; Desoxycorticosterone; Dihydropyridines; Disease Models, Animal; Hypertension; Intracellular Signaling Peptides and Proteins; Kidney; Male; Membrane Proteins; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System; Sodium Chloride; Transforming Growth Factor beta; Treatment Outcome | 2011 |
Effects of an N-type calcium antagonist on angiotensin II-renin feedback.
Topics: Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Dose-Response Relationship, Drug; Male; Models, Biological; Rats; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2011 |
Effects of hypertension and ovariectomy on rat hepatocytes. Are amlodipine and lacidipine protective? (A stereological and histological study).
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cytoprotection; Dihydropyridines; Female; Hepatocytes; Hypertension; Liver; Ovariectomy; Postmenopause; Rats; Rats, Inbred Strains | 2010 |
Comparative effects of azelnidipine and amlodipine on myocardial function and mortality after ischemia/reperfusion in dogs.
Topics: Amlodipine; Animals; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Dog Diseases; Dogs; Energy Metabolism; Female; Male; Myocardium; Reperfusion Injury | 2011 |
Intravascular ultrasound parameters in non-inferiority trial.
Topics: Amlodipine; Azetidinecarboxylic Acid; Coronary Artery Disease; Dihydropyridines; Humans; Hypertension | 2011 |
Cilnidipine, but not amlodipine, ameliorates osteoporosis in ovariectomized hypertensive rats through inhibition of the N-type calcium channel.
Topics: Amlodipine; Animals; Antihypertensive Agents; Bone and Bones; Bone Density; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Female; Osteoporosis; Ovariectomy; Rats; Rats, Inbred SHR | 2012 |
Effects of calcium antagonists and agonists on isolated human v. saphena magna used for coronary artery bypass grafting and guinea pig's papillary muscle.
Topics: Action Potentials; Adult; Aged; Aged, 80 and over; Amlodipine; Animals; Benzimidazoles; Calcium Channel Agonists; Calcium Channel Blockers; Coronary Artery Bypass; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; In Vitro Techniques; Isometric Contraction; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Papillary Muscles; Phenylephrine; Saphenous Vein; Vasoconstrictor Agents | 2011 |
Distinct properties of amlodipine and nicardipine block of the voltage-dependent Ca2+ channels Cav1.2 and Cav2.1 and the mutant channels Cav1.2/dihydropyridine insensitive and Cav2.1/dihydropyridine sensitive.
Topics: Amino Acid Sequence; Amlodipine; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; HEK293 Cells; Humans; Molecular Sequence Data; Mutation; Nicardipine; Protein Conformation | 2011 |
Azelnidipine attenuates glomerular damage in Dahl salt-sensitive rats by suppressing sympathetic nerve activity.
Topics: Amlodipine; Animals; Arterioles; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Heart Rate; Kidney Diseases; Kidney Glomerulus; Male; Rats; Rats, Inbred Dahl; Sympathectomy; Sympathetic Nervous System | 2012 |
[Shortening of donepezil-induced QTc prolongation with a change in the interacting drug, after electrocardiograph monitoring by community pharmacists: a case report].
Topics: Aged, 80 and over; Amlodipine; Cholinesterase Inhibitors; Community Pharmacy Services; Dihydropyridines; Donepezil; Drug Interactions; Electrocardiography, Ambulatory; Female; Humans; Indans; Pharmacists; Piperidines; Risk; Risk Management; Torsades de Pointes | 2012 |
Effects of dihydropyridine calcium channel blockers on oxidized low-density lipoprotein induced proliferation and oxidative stress of vascular smooth muscle cells.
Topics: Amlodipine; Anthracenes; Butadienes; Calcium Channel Blockers; Cell Proliferation; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipoproteins, LDL; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Time Factors | 2012 |
Effects of cilnidipine on serum uric acid level and urinary nitrogen monoxide excretion in patients with hypertension.
Topics: Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Nitric Oxide; Treatment Outcome; Uric Acid | 2012 |
Comparison of the effects of cilnidipine and amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats.
Topics: Amlodipine; Animals; Blotting, Western; Calcium Channel Blockers; Diastole; Dihydropyridines; Immunohistochemistry; Male; Myocardium; Oxidative Stress; Rats; Rats, Inbred Dahl; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Action of calcium antagonists and agonists on isolated human thoracic arteries used for coronary artery bypass grafting.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Benzimidazoles; Calcium Channel Agonists; Calcium Channel Blockers; Carbachol; Coronary Artery Bypass; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Pyridines; Thoracic Arteries | 2012 |
Hypertension in older adults: progress and limitations.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Imidazoles; Male; Tetrazoles | 2012 |
Additive effects of cilnidipine and angiotensin II receptor blocker in preventing the progression of diabetic nephropathy in diabetic spontaneously hypertensive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dihydropyridines; Disease Progression; Drug Therapy, Combination; Glomerulonephritis; Glucagon; Glucose Transporter Type 1; Glycated Hemoglobin; Glycogen; Hypertension; Kidney; Male; Norepinephrine; Proteinuria; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan | 2013 |
The pharmacological differences in antianginal effects of long-lasting calcium channel blockers: azelnidipine and amlodipine.
Topics: Administration, Oral; Amlodipine; Angina Pectoris; Animals; Arginine Vasopressin; Azetidinecarboxylic Acid; Blood Pressure; Calcium; Calcium Channel Blockers; Coronary Vessels; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Male; Myocardium; Oxygen Consumption; Rats; Swine; Time Factors; Vasoconstriction | 2013 |
Involvement of N-type Ca(2+) channels in the fibrotic process of the kidney in rats.
Topics: Actins; Amlodipine; Animals; Cadherins; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cell Proliferation; Dihydropyridines; Disease Models, Animal; Epithelial-Mesenchymal Transition; Kidney; Macrophages; Male; Rats; Rats, Wistar; Ureteral Obstruction | 2013 |
Voltage-dependent N-type Ca2+ channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice.
Topics: Amlodipine; Angiotensin II; Animals; Aorta, Thoracic; Biomarkers; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemodynamics; Hypertension; Macrophages; Mice; omega-Conotoxin GVIA; Oxidative Stress; Reactive Oxygen Species; Vasodilation; Vasodilator Agents | 2013 |
Effect of azelnidipine and amlodipine on single cell mechanics in mouse cardiomyocytes.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Animals; Azetidinecarboxylic Acid; Biomechanical Phenomena; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Imidazoles; Mechanical Phenomena; Mice; Myocytes, Cardiac; Single-Cell Analysis; Tetrazoles | 2013 |
The role of external Ca²⁺ in the action of Ca²⁺-channel agonists and antagonists on isolated human thoracic arteries.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Benzimidazoles; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Female; Humans; In Vitro Techniques; Isometric Contraction; Male; Middle Aged; Milrinone; Thoracic Arteries | 2014 |
Discovering the sympathomodulatory properties of new calcium channel blockers: an exciting but still snaky journey.
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Baroreflex; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Male; Sympathetic Nervous System | 2014 |
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology.
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Drug Costs; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Nephrology; Patient Satisfaction; Practice Patterns, Physicians'; Renal Insufficiency, Chronic; Retrospective Studies; Surveys and Questionnaires; Telmisartan; Tetrazoles; Valsartan | 2015 |
Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Dihydropyridines; Drug Evaluation, Preclinical; Drug Therapy, Combination; Heart; Hypertension; Hypertrophy, Left Ventricular; Male; Myocytes, Cardiac; Oxidative Stress; Rats, Inbred Dahl; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Ventricular Remodeling | 2015 |
Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children.
Topics: Adolescent; Amlodipine; Calcium Channel Blockers; Child; Child, Preschool; Cyclosporine; Dihydropyridines; Drug Interactions; Female; Hematopoietic Stem Cell Transplantation; Humans; Hypertension; Immunosuppressive Agents; Infant; Male; Nicardipine; Retrospective Studies | 2014 |
Continuous venovenous hemodiafiltration along with charcoal hemoperfusion for the management of life-threatening lercanidipine and amlodipine overdose.
Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Charcoal; Dihydropyridines; Drug Overdose; Hemodiafiltration; Hemoperfusion; Humans; Male; Multiple Organ Failure; Shock; Time Factors; Treatment Outcome | 2014 |
Single-pill combination therapy in the initial treatment of marked hypertension: a propensity-matched analysis.
Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Drug Combinations; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Propensity Score; Ramipril; Retrospective Studies; Risk Factors; Telmisartan; Tetrazoles | 2015 |
Cilnidipine but not amlodipine suppresses sympathetic activation elicited by isometric exercise in hypertensive patients.
Topics: Aged; Amlodipine; Autonomic Nervous System; Calcium Channel Blockers; Dihydropyridines; Exercise; Female; Hand Strength; Humans; Hypertension; Male; Middle Aged; Miosis; Mydriasis; Pupil; Reproducibility of Results | 2015 |
Effects of Administration of Amlodipine and Lacidipine on Inflammation-Induced Bone Loss in the Ovariectomized Rat.
Topics: Amlodipine; Animals; Bone Density; Calcium Channel Blockers; Collagen Type I; Collagen Type I, alpha 1 Chain; Core Binding Factor Alpha 1 Subunit; Dihydropyridines; Female; Humans; Hypertension; Inflammation; Interleukin-1beta; Interleukin-6; Osteocalcin; Osteopontin; Osteoporosis; Ovariectomy; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2016 |
Comparative effect of fixed-dose combination tablets of candesartan cilexetil/amlodipine versus olmesartan medoxomil/azelnidipine on laboratory parameters in patients with hypertension: a retrospective cohort study.
Topics: Aged; Alanine Transaminase; Amlodipine; Antihypertensive Agents; Aspartate Aminotransferases; Azetidinecarboxylic Acid; Benzimidazoles; Biphenyl Compounds; Blood Urea Nitrogen; Cohort Studies; Creatinine; Dihydropyridines; Drug Combinations; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Olmesartan Medoxomil; Potassium; Propensity Score; Retrospective Studies; Sodium; Tetrazoles; Uric Acid | 2016 |
Failure of intravenous lipid emulsion in treatment of cardiotoxicity caused by mixed overdose including dihydropyridine calcium channel blockers.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Cardiotoxicity; Dihydropyridines; Emergencies; Fat Emulsions, Intravenous; Fatal Outcome; Female; Heart Arrest; Humans; Male; Treatment Failure | 2016 |
Effects of azelnidipine and amlodipine on exercise-induced sympathoexcitation assessed by pupillometry in hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Autonomic Nervous System; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Essential Hypertension; Exercise; Female; Humans; Hypertension; Male; Middle Aged; Pupil | 2016 |
On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Valsartan | 2016 |
Structural basis for inhibition of a voltage-gated Ca
Topics: Allosteric Regulation; Amines; Amlodipine; Animals; Bacterial Proteins; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Crystallography, X-Ray; Dihydropyridines; Lipids; Models, Molecular; Moths; Mutation; Niacin; Protein Subunits; Verapamil | 2016 |
Cilnidipine: Next Generation Calcium Channel Blocker.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Humans; Hypertension; India; Middle Aged | 2016 |
Replacement of Amlodipine and Lercanidipine by Barnidipine: Tolerability and Effectiveness in a Real-Life Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Substitution; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Product Surveillance, Postmarketing; Prospective Studies; Time Factors; Treatment Outcome | 2017 |
[The Effectiveness of Combination Antihypertensive Therapy in Women With Hypothyroidism and the Metabolic Syndrome].
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Hypothyroidism; Imidazoles; Losartan; Metabolic Syndrome; Middle Aged | 2016 |
Long-term outcomes of lercanidipine versus other calcium channel blockers in newly diagnosed hypertension: a nationwide cohort study.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Cohort Studies; Dihydropyridines; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Stroke; Taiwan; Young Adult | 2017 |
Effects of L- and N-Type Ca Channel Blocker Cilnidipine on Changes in Heart Rate and QT Interval During Dialysis.
Topics: Aged; Amlodipine; Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Renal Dialysis; Sympathetic Nervous System | 2017 |
Comparison between L-type and N/L-type calcium channel blockers in the regulation of home blood-pressure variability in elderly hypertensive patients.
Topics: Aged; Amlodipine; Ankle Brachial Index; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Catecholamines; Dihydropyridines; Female; Humans; Hypertension; Male; Prospective Studies; Sympathetic Nervous System; Vascular Stiffness | 2018 |
Moderate hypothermia and responses to calcium channel blockers - Role of the nitric oxide.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cold Temperature; Coronary Vessels; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypothermia, Induced; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase Type III; Vasodilation; Vasodilator Agents; Verapamil | 2018 |
Successful re-administration of Pazopanib in a patient with metastatic renal cell carcinoma and a history of Pazopanib-induced nephrotic syndrome: a case report.
Topics: Aged; Amlodipine; Angiogenesis Inhibitors; Antihypertensive Agents; Antineoplastic Agents; Carcinoma, Renal Cell; Combined Modality Therapy; Diabetic Nephropathies; Dihydropyridines; Drug Substitution; Edema; Everolimus; Humans; Hypertension; Indazoles; Kidney Failure, Chronic; Lung Neoplasms; Male; Nephrotic Syndrome; Nivolumab; Pancreatic Neoplasms; Pancreaticoduodenectomy; Pneumonectomy; Protein Kinase Inhibitors; Pyrimidines; Sirolimus; Sulfonamides; Sunitinib | 2019 |
Efficacy and safety of a combination antihypertensive drug (olmesartan plus azelnidipine): "Issues with hypertension studies in real-world practice".
Topics: Amlodipine; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Combinations; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2020 |
Single-pill combination of cilnidipine, an L-/N-type calcium channel blocker, and valsartan effectively reduces home pulse pressure in patients with uncontrolled hypertension and sympathetic hyperactivity: The HOPE-Combi survey.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan | 2020 |
Comparison of effects of L/N-type and L-type calcium channel blockers on post-infarct cardiac remodelling in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Signaling; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hypertension; Male; Myocardial Infarction; Norepinephrine; Rats, Inbred SHR; Renin-Angiotensin System; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Binding Sites; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cryoelectron Microscopy; Dihydropyridines; Molecular Dynamics Simulation; Nanostructures; Protein Structure, Tertiary; Stereoisomerism | 2021 |
Single-pill combination of cilnidipine, an l-/n-type calcium channel blocker, and valsartan reduces the day-by-day variability of morning home systolic blood pressure in patients with treated hypertension: A sub-analysis of the HOPE-combi survey.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan | 2021 |
Calcium channel blockers lercanidipine and amlodipine inhibit YY1/ERK/TGF-β mediated transcription and sensitize the gastric cancer cells to doxorubicin.
Topics: Amlodipine; Antibiotics, Antineoplastic; Calcium Channel Blockers; Cell Line; Cell Survival; Dihydropyridines; Doxorubicin; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Stomach Neoplasms; Transcription, Genetic; Transcriptome; Transforming Growth Factor beta; YY1 Transcription Factor | 2021 |
Cilnidipine for Amlodipine Induced Pedal Edema and its Anti-hypertensive Effect in a Tertiary Care Teaching Hospital of Western Nepal.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Edema; Hospitals, Teaching; Humans; Male; Middle Aged; Nepal; Prospective Studies; Tertiary Healthcare | 2021 |
Gingival enlargement improvement following medication change from amlodipine to benidipine and periodontal therapy.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Female; Gingival Hyperplasia; Gingival Overgrowth; Humans; Hypertension | 2022 |
Delayed Decline of Cognitive Function by Antihypertensive Agents: A Cohort Study Linked with Genotype Data.
Topics: Adrenergic Antagonists; Adult; Aged; Amlodipine; Antihypertensive Agents; Apolipoprotein E4; Calcium Channel Blockers; Cognition; Cohort Studies; Dihydropyridines; Diuretics; Diuretics, Potassium Sparing; Genotype; Humans; Hypertension; Nifedipine; Thiazides; Vasodilator Agents | 2022 |