amlodipine and digoxin

amlodipine has been researched along with digoxin in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's1 (4.76)18.2507
2000's6 (28.57)29.6817
2010's11 (52.38)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Schwartz, JB1
Abernethy, DR1
Struthers, AD1
Bondioli, A; Calabresi, L; De Rosa, C; Ferrara, S; Mombelli, G; Pazzucconi, F; Sirtori, CR; Yeates, R; Zoppi, F1
Higashide, T; Kakihara, M; Mizumura, T; Ogata, I; Okai, T; Oshima, A; Sugimura, Y; Tamamura, T; Tonoike, N; Yoshida, S1
Dunnington, GH; Johri, S; Vnencak-Jones, CL1
Del Giaccio, A; Eblen-Zajjur, A1
Baig, AM; Iqbal, J; Khan, NA1
Baig, AM; Khan, NA; Kulsoom, H; Siddiqui, R1
Borek-Dohalska, L; Fojtikova, V; Martinkova, M; Mináriková, M; Sedláček, J; Šikut, M; Stiborová, M; Vyskočilová, E1
Irie, S; Ishizuka, H; Ishizuka, T; Kato, M; Kirigaya, Y; Nakatsu, T; Nishikawa, Y; Shimizu, T; Shiramoto, M; Uchimaru, H1

Reviews

3 review(s) available for amlodipine and digoxin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The pharmacokinetic profile of amlodipine.
    American heart journal, 1989, Volume: 118, Issue:5 Pt 2

    Topics: Administration, Oral; Aging; Amlodipine; Angina Pectoris; Animals; Biological Availability; Calcium Channel Blockers; Cimetidine; Digoxin; Drug Interactions; Half-Life; Humans; Injections, Intravenous; Kidney Diseases; Liver Cirrhosis; Nifedipine

1989
Rationalizing the heart failure trials: from theory to practice.
    European heart journal, 1997, Volume: 18 Suppl E

    Topics: Adrenergic beta-Antagonists; Amiodarone; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Blood Pressure; Clinical Trials as Topic; Digoxin; Diuretics; Heart Failure; Humans; Hydralazine; Treatment Outcome; Vasodilator Agents

1997

Trials

3 trial(s) available for amlodipine and digoxin

ArticleYear
Effects of amlodipine on steady-state digoxin concentrations and renal digoxin clearance.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:1

    Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Digoxin; Drug Interactions; Electrocardiography; Humans; Kidney; Male; Nifedipine

1988
Cardiovascular drugs in human mechanical nociception: digoxin, amlodipine, propranolol, pindolol and atenolol.
    Investigacion clinica, 2010, Volume: 51, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Cardiovascular Diseases; Cross-Sectional Studies; Digoxin; Female; Humans; Male; Middle Aged; Nociceptors; Pindolol; Propranolol; Young Adult

2010
Pharmacokinetic interactions of esaxerenone with amlodipine and digoxin in healthy Japanese subjects.
    BMC pharmacology & toxicology, 2020, 07-29, Volume: 21, Issue:1

    Topics: Adult; Amlodipine; Antihypertensive Agents; Asian People; Calcium Channel Blockers; Cross-Over Studies; Digoxin; Drug Interactions; Healthy Volunteers; Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Pyrroles; Sulfones; Young Adult

2020

Other Studies

15 other study(ies) available for amlodipine and digoxin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a model based on body composition to predict drug kinetics-1 evaluation in healthy volunteers.
    Pharmacological research, 2004, Volume: 50, Issue:1

    Topics: Adult; Aged; Algorithms; Amlodipine; Anesthetics, Local; Anti-Bacterial Agents; Antihypertensive Agents; Area Under Curve; Body Composition; Body Water; Cardiotonic Agents; Digoxin; Electric Impedance; Half-Life; Humans; Intracellular Fluid; Lidocaine; Models, Biological; Pharmacokinetics; Tobramycin

2004
[Basedow disease with recurrent syncopal attack and severe pulmonary hypertension].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Apr-10, Volume: 96, Issue:4

    Topics: Aged; Amlodipine; Atrial Fibrillation; Digoxin; Female; Graves Disease; Humans; Hypertension, Pulmonary; Methimazole; Recurrence; Syncope; Treatment Outcome; Vertigo

2007
A novel BMPR2 mutation associated with pulmonary arterial hypertension in an octogenarian.
    Lung, 2010, Volume: 188, Issue:4

    Topics: Aged, 80 and over; Amlodipine; Bone Morphogenetic Protein Receptors, Type II; Bosentan; Digoxin; Dyspnea; Humans; Hypertension, Pulmonary; Male; Pulmonary Artery; Sulfonamides; Warfarin

2010
In vitro efficacies of clinically available drugs against growth and viability of an Acanthamoeba castellanii keratitis isolate belonging to the T4 genotype.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:8

    Topics: Acanthamoeba castellanii; Amlodipine; Antiprotozoal Agents; Culture Media; Digoxin; Drug Evaluation, Preclinical; Genotype; Haloperidol; Loperamide; Parasitic Sensitivity Tests; Prochlorperazine; Trophozoites

2013
Combined drug therapy in the management of granulomatous amoebic encephalitis due to Acanthamoeba spp., and Balamuthia mandrillaris.
    Experimental parasitology, 2014, Volume: 145 Suppl

    Topics: Acanthamoeba castellanii; Amebiasis; Amebicides; Amiodarone; Amlodipine; Apomorphine; Balamuthia mandrillaris; Brain; Cells, Cultured; Digoxin; Drug Synergism; Drug Therapy, Combination; Encephalitis; Endothelial Cells; Haloperidol; Humans; Loperamide; Microvessels; Prochlorperazine; Procyclidine

2014
The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study.
    Environmental toxicology and pharmacology, 2017, Volume: 52

    Topics: Adsorption; Alpha-Amanitin; Amlodipine; Antidotes; Aspirin; Carbamazepine; Charcoal; Digoxin; Ibuprofen; Imipramine; Oxazepam; Phenobarbital; Poisoning; Promethazine; Silicates; Theophylline

2017