amlodipine has been researched along with cilnidipine in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.85) | 18.2507 |
| 2000's | 14 (26.92) | 29.6817 |
| 2010's | 31 (59.62) | 24.3611 |
| 2020's | 5 (9.62) | 2.80 |
| Authors | Studies |
|---|---|
| Reimão, JQ; Scotti, MT; Tempone, AG | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Miho, N; Nawada, R; Obayashi, K; Sakata, K; Shirotani, M; Togi, K; Yoshida, H | 1 |
| Karasawa, A; Kobayashi, S; Kosaka, N; Nito, M; Nomura, H; Sonoda, R; Tanaka, H; Yamaguchi, K | 1 |
| Hirano, K; Kimura, R; Ohashi, K; Urayama, A; Watanabe, H; Yamada, S | 1 |
| Doba, N; Kimura, Y; Kinouchi, T; Kuwabara, Y; Kuwata, S; Maruyama, C; Tomiyama, H; Yoshida, H; Yoshida, Y | 1 |
| Shigematsu, M; Takami, T | 1 |
| Kojima, S; Shida, M; Yokoyama, H | 1 |
| Miyachi, Y; Ueshiba, H | 1 |
| Enomoto, A; Konda, T; Matsushita, J; Moriyama, T; Takahara, A | 1 |
| Eguchi, K; Hoshide, S; Ishikawa, J; Kario, K; Shimada, K | 1 |
| Iwasaka, T; Maki, K; Morimoto, S; Yano, Y | 1 |
| Ando, K; Fujita, T; Ideura, T; Isshiki, M; Nishimura, H; Takahashi, K; Yasuda, G | 1 |
| Ishii, K; Kawakami, T; Kuwagata, M; Nakahara, T; Saito, M; Sakamoto, K; Shimada, M; Yamaguchi, A | 1 |
| Aritomi, S; Enomoto, A; Koganei, H; Konda, T; Niinuma, K; Nitta, K; Ogawa, T | 1 |
| Fujita, T; Fujito, T; Hishikawa, K; Idei, M; Takase, O | 1 |
| Araki, N; Furuya, D; Ohkubo, T; Shimazu, K; Takei, K; Tamura, N; Yamamoto, T; Yanagisawa, CT | 1 |
| Akie, Y; Aritomi, S; Nakamura, Y; Nakayama, A; Satoh, Y; Sugiyama, A; Takahara, A; Wagatsuma, H | 1 |
| Hirooka, Y; Sunagawa, K | 1 |
| Araki, N; Ito, Y | 1 |
| Aiba, N; Hara, M; Izumi, T; Kutsuna, T; Masuda, T; Matsumoto, T; Moriya, T; Noda, C; Ogura, MN; Takahira, N | 1 |
| Asanuma, K; Fan, YY; Fujita, T; Hitomi, H; Kobori, H; Kohno, M; Nakano, D; Nishiyama, A; Noma, T; Ohashi, N; Ohsaki, H; Suwarni, D; Tomino, Y | 1 |
| Arakawa, K; Fujii, M; Inoki, I; Kimura, T; Konoshita, T; Makino, Y; Miyamori, I; Nakamura, H; Wakahara, S | 1 |
| Kawano, Y; Matsuoka, H; Miwa, Y; Ohta, Y; Sasaguri, T; Tominaga, M; Tsuchihashi, T; Ueno, M | 1 |
| Aritomi, S; Koganei, H; Konda, T; Mitsui, A; Nitta, K; Ogawa, T; Wagatsuma, H | 1 |
| Kobara, M; Kojima, Y; Nakano, A; Nakata, T; Noda, K; Oshima, Y; Toba, H; Tojo, C; Wang, J; Yoshida, M | 1 |
| Aritomi, S; Konda, T; Niinuma, K; Nitta, K; Ogawa, T | 2 |
| Ando, K; Babazono, T; Fujita, T; Kario, K; Matsuoka, H; Nakao, K; Tanaka, S; Ueshima, K | 1 |
| Koriyama, H; Kyutoku, M; Mariana, OK; Morishita, R; Nakagami, F; Nakagami, H; Rakugi, H; Shimamura, M; Shimizu, H; Yasumasa, N | 1 |
| Hamada, T; Hasegawa, A; Hisatome, I; Ishida, K; Kato, M; Mishima, M; Miyazaki, S; Mizuta, E; Ninomiya, H; Nosaka, Y; Ogino, K; Ohtahara, A; Osaki, T; Sakata, S; Taniguchi, S; Watanabe, A; Yamada, K; Yamamoto, K; Yoshida, A | 1 |
| Fujita, M; Ikai, A; Mitani, S; Miyamoto, S; Ogura, C; Ono, K; Sugimoto, N; Tanaka, S | 1 |
| Kawano, K; Kitani, M; Koshiba, K; Kusunose, K; Orino, S; Sata, M; Soeki, T; Taketani, Y; Wakatsuki, T; Yagi, S | 1 |
| Aritomi, S; Hattori, T; Ito, H; Kato, M; Murase, T; Murohara, T; Nagata, K; Nakashima, C; Nashima, K; Niinuma, K; Ohtake, M; Takahashi, K; Takatsu, M | 1 |
| Abe, M; Inoshita, A; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Yoshida, Y | 1 |
| Hiromura, K; Ikeuchi, H; Maeshima, A; Mishima, K; Miya, M; Nojima, Y; Sakurai, N | 1 |
| Aritomi, S; Harada, E; Hirano, K; Ishikawa, T; Kim-Mitsuyama, S; Kuwahara, K; Mori, Y; Nishida, M; Saiki, S; Sunggip, C | 1 |
| Ando, K; Fujita, T; Kosugi, S; Matsuoka, H; Nakao, K; Sato, T; Tanaka, S; Ueshima, K | 1 |
| Harada, E; Hattori, T; Matsuura, N; Murohara, T; Nagasawa, K; Nagata, K; Niinuma, K; Takahashi, K; Takatsu, M; Watanabe, S | 1 |
| Fujita, M; Hikita, T; Itakura, H; Ito, K; Ito, T; Mizuno, S; Mochizuki, K; Morita, T; Nakai, K; Ohno, Y; Saito, T; Shin, I; Soma, M; Sugawara, M; Takahashi, M; Takahashi, Y; Uchida, S | 1 |
| Hano, T; Iwane, N; Kawabe, T; Koike, Y; Nishihara, K | 1 |
| Eguchi, A; Fujiwara, S; Hirotani, S; Komamura, K; Koshiba, M; Mano, T; Masaki, M; Masuyama, T; Sugahara, M; Tsujino, T | 1 |
| Fujii, M; Ichikawa, M; Imagawa, M; Ishizuka, T; Kaeriyama, S; Konoshita, T; Makino, Y; Nakamura, H; Nakaya, T; Sato, S; Suzuki, J; Urabe, M; Wakahara, S; Yamada, M; Yamamoto, K; Zenimaru, Y | 1 |
| Shete, MM | 1 |
| Cha, BS; Chung, CH; Hwang, YC; Jang, HC; Lee, KW; Lee, MK; Min, KW; Yoon, KH | 1 |
| Amari, Y; Ando, T; Ichihara, A; Iida, T; Morimoto, S | 1 |
| Akasaka, H; Hongyo, K; Ito, N; Nozato, S; Nozato, Y; Rakugi, H; Sugimoto, K; Takami, Y; Takeda, M; Takeya, M; Takeya, Y; Yamamoto, K | 1 |
| Kario, K; Kurose, Y; Matsuda, S; Nagahama, S; Sugii, H; Suzuki, N; Teshima, T | 2 |
| Kobara, M; Nakata, T; Naseratun, N; Toba, H; Watanabe, Y | 1 |
| D, DC; Jj, NK; Kavitha, R | 1 |
| Kafle, RC; Maskey, A; Sapkota, S | 1 |
2 review(s) available for amlodipine and cilnidipine
| Article | Year |
|---|---|
[Calcium antagonists: current and future applications based on new evidence. Calcium channel blockers and autonomic nervous system].
Topics: Amlodipine; Antihypertensive Agents; Antioxidants; Autonomic Nervous System; Azetidinecarboxylic Acid; Calcium Channel Blockers; Dihydropyridines; Heart Rate; Humans | 2010 |
[Calcium antagonists: current and future applications based on new evidence. Neuroprotective effect of calcium antagonists].
Topics: Amlodipine; Animals; Brain Edema; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cell Death; Cerebral Infarction; Dihydropyridines; Hippocampus; Humans; Neurons; Neuroprotective Agents; omega-Conotoxins; Rats | 2010 |
20 trial(s) available for amlodipine and cilnidipine
| Article | Year |
|---|---|
Effects of amlodipine and cilnidipine on cardiac sympathetic nervous system and neurohormonal status in essential hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Heart; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Reference Values; Renin; Sympathetic Nervous System | 1999 |
Cilnidipine more highly attenuates cold pressor stress-induced platelet activation in hypertension than does amlodipine.
Topics: Amlodipine; beta-Thromboglobulin; Blood Pressure; Calcium Channel Blockers; Cold Temperature; Cross-Over Studies; Dihydropyridines; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Platelet Activation; Stress, Physiological; Sympathetic Nervous System | 2001 |
Effects of calcium channel antagonists on left ventricular hypertrophy and diastolic function in patients with essential hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diastole; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine | 2003 |
Comparison between cilnidipine and amlodipine besilate with respect to proteinuria in hypertensive patients with renal diseases.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Calcium Channels, N-Type; Creatinine; Dihydropyridines; Female; Humans; Hypertension, Renal; Logistic Models; Male; Middle Aged; Proteinuria; Treatment Outcome | 2004 |
Effects of the long-acting calcium channel blockers, amlodipine, manidipine and cilnidipine on steroid hormones and insulin resistance in hypertensive obese patients.
Topics: Aged; Amlodipine; Analysis of Variance; Body Mass Index; Calcium Channel Blockers; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Delayed-Action Preparations; Dihydropyridines; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Insulin Resistance; Male; Middle Aged; Nitrobenzenes; Obesity; Piperazines; Probability; Reference Values; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2004 |
Comparison of the effects of cilnidipine and amlodipine on ambulatory blood pressure.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Dihydropyridines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 2005 |
Renal and vascular protective effects of cilnidipine in patients with essential hypertension.
Topics: Albuminuria; Amlodipine; Antihypertensive Agents; Arteries; Calcium Channel Blockers; Dihydropyridines; Endothelium, Vascular; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Safety; Vasodilation | 2007 |
Antiproteinuric effect of the calcium channel blocker cilnidipine added to renin-angiotensin inhibition in hypertensive patients with chronic renal disease.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Creatinine; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension, Renal; Male; Middle Aged; Proteinuria; Renal Insufficiency, Chronic; Renin-Angiotensin System; Treatment Outcome | 2007 |
Comparison of the anti-hypertensive effects of the L/N-type calcium channel antagonist cilnidipine, and the L-type calcium channel antagonist amlodipine in hypertensive patients with cerebrovascular disease.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cerebrovascular Disorders; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged | 2009 |
A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin I; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 2010 |
Antiproteinuric effect of cilnidipine in hypertensive Japanese treated with renin-angiotensin-system inhibitors - a multicenter, open, randomized trial using 24-hour urine collection.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Japan; Male; Proteinuria; Treatment Outcome | 2010 |
Design and rationale of the study of assessment for kidney function by urinary microalbumin in randomized (SAKURA) trial.
Topics: Aged; Albuminuria; Amlodipine; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Clinical Protocols; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Female; Humans; Hypertension; Kidney Function Tests; Male; Middle Aged; Renin-Angiotensin System | 2011 |
L/T-type and L/N-type calcium-channel blockers attenuate cardiac sympathetic nerve activity in patients with hypertension.
Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cross-Over Studies; Dihydropyridines; Female; Heart; Heart Conduction System; Hemodynamics; Humans; Hypertension; Male; Nitrophenols; Norepinephrine; Organophosphorus Compounds; Prospective Studies; Sympathetic Nervous System | 2012 |
Renoprotective and antioxidant effects of cilnidipine in hypertensive patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Antioxidants; Blood Pressure; Calcium Channel Blockers; Deoxyguanosine; Dihydropyridines; Fatty Acid-Binding Proteins; Female; Heart Rate; Humans; Hypertension; Incidence; Male; Middle Aged; Oxidative Stress; Prospective Studies; Renal Insufficiency, Chronic | 2012 |
L/N-type calcium channel blocker cilnidipine reduces plasma aldosterone, albuminuria, and urinary liver-type fatty acid binding protein in patients with chronic kidney disease.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Creatinine; Dihydropyridines; Down-Regulation; Fatty Acid-Binding Proteins; Female; Humans; Hypertension; Japan; Linear Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Renal Insufficiency, Chronic; Time Factors; Treatment Outcome | 2013 |
Comparison of the antialbuminuric effects of L-/N-type and L-type calcium channel blockers in hypertensive patients with diabetes and microalbuminuria: the study of assessment for kidney function by urinary microalbumin in randomized (SAKURA) trial.
Topics: Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System | 2013 |
Effects of the N/L-type calcium channel blocker cilnidipine on nephropathy and uric acid metabolism in hypertensive patients with chronic kidney disease (J-CIRCLE study).
Topics: Aged; Aged, 80 and over; Albuminuria; Amlodipine; Blood Pressure; Calcium Channel Blockers; Creatinine; Cross-Over Studies; Diabetic Nephropathies; Dihydropyridines; Dose-Response Relationship, Drug; Drug Substitution; Female; Humans; Hypertension, Renal; Japan; Kidney Failure, Chronic; Male; Middle Aged; Nephrosclerosis; Uric Acid | 2014 |
Long-term effects of L- and N-type calcium channel blocker on uric acid levels and left atrial volume in hypertensive patients.
Topics: Amlodipine; Atrial Function, Left; Atrial Remodeling; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; China; Diastole; Dihydropyridines; Down-Regulation; Echocardiography, Doppler; Female; Humans; Hypertension; Hyperuricemia; Male; Middle Aged; Time Factors; Treatment Outcome; Uric Acid; Ventricular Dysfunction, Left; Ventricular Function, Left | 2016 |
Reduction in microalbuminuria by calcium channel blockers in patients with type 2 diabetes mellitus and hypertension-A randomized, open-label, active-controlled, superiority, parallel-group clinical trial.
Topics: Adult; Aged; Albuminuria; Amlodipine; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Treatment Outcome | 2017 |
A Randomized Open-Label Parallel-Group Study Comparing the Efficacy and Safety of Cilnidipine and Amlodipine in Hypertensive Adults.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension; India | 2022 |
30 other study(ies) available for amlodipine and cilnidipine
| Article | Year |
|---|---|
Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cricetinae; Dihydropyridines; Erythrocytes; Leishmania; Macaca mulatta; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
[Effects of benidipine hydrochloride (Coniel) on blood pressure, heart rate and plasma norepinephrine concentration in spontaneously hypertensive rats].
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Heart Rate; Hypertension; Male; Nifedipine; Norepinephrine; Rats; Rats, Inbred SHR | 1999 |
Improvement in the histopathology of hearts from cardiomyopathic BIO TO-2 hamsters following long-term administration of amlodipine and cilnidipine.
Topics: Amlodipine; Animals; Animals, Inbred Strains; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiomyopathies; Cricetinae; Dihydropyridines; Heart; Kinetics; Male; Mesocricetus; Myocardium; Organ Size | 2000 |
The N- and L-type calcium channel blocker cilnidipine suppresses renal injury in dahl rats fed a high-sucrose diet, an experimental model of metabolic syndrome.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dietary Sucrose; Dihydropyridines; Disease Models, Animal; Hypertension, Renal; Kidney Diseases; Male; Metabolic Syndrome; Rats; Rats, Inbred Dahl; Treatment Outcome | 2005 |
Histological protection by cilnidipine, a dual L/N-type Ca(2+) channel blocker, against neurotoxicity induced by ischemia-reperfusion in rat retina.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Drug Evaluation, Preclinical; In Situ Nick-End Labeling; Injections; Injections, Intravenous; Male; N-Methylaspartate; Neuroprotective Agents; Nitroso Compounds; omega-Conotoxins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Retinal Degeneration; Retinal Diseases; Vitreous Body | 2009 |
Different effects of L/N-type and L-type calcium channel blockers on the renin-angiotensin-aldosterone system in SHR/Izm.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Conotoxins; Dihydropyridines; Humans; Male; Norepinephrine; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Time Factors | 2009 |
Comparison of antioxidant activity of cilnidipine and amlodipine.
Topics: Amlodipine; Antioxidants; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Mesangial Cells; Superoxides | 2009 |
Long-term blockade of L/N-type Ca(2+) channels by cilnidipine ameliorates repolarization abnormality of the canine hypertrophied heart.
Topics: Action Potentials; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrioventricular Block; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cardiomegaly; Chronic Disease; Dihydropyridines; Dogs; Electrocardiography; Epinephrine; Female; Male; Neurotransmitter Agents; Norepinephrine; Tetrazoles; Time Factors | 2009 |
Beneficial effects of L- and N-type calcium channel blocker on glucose and lipid metabolism and renal function in patients with hypertension and type II diabetes mellitus.
Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Diabetes Mellitus, Type 2; Dihydropyridines; Female; Glucose; Humans; Hypertension; Kidney; Lipid Metabolism; Male; Middle Aged | 2011 |
Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: possible involvement of N-type calcium channel in podocyte.
Topics: Amlodipine; Animals; Base Sequence; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Calcium Channels, N-Type; Creatinine; Dihydropyridines; Disease Models, Animal; DNA Primers; Humans; Kidney; Male; Metabolic Syndrome; Oxidative Stress; Podocytes; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger; RNA, Small Interfering; Triglycerides | 2010 |
The N-type and L-type calcium channel blocker cilnidipine suppresses renal injury in Dahl rats fed a high-salt diet.
Topics: Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Glomerulonephritis; Hypertension; Kidney; Kidney Diseases; Male; Organ Size; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Time Factors; Valine; Valsartan | 2010 |
L/N-type calcium channel blocker cilnidipine ameliorates proteinuria and inhibits the renal renin-angiotensin-aldosterone system in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Collagen; Desoxycorticosterone; Dihydropyridines; Disease Models, Animal; Hypertension; Intracellular Signaling Peptides and Proteins; Kidney; Male; Membrane Proteins; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System; Sodium Chloride; Transforming Growth Factor beta; Treatment Outcome | 2011 |
Effects of an N-type calcium antagonist on angiotensin II-renin feedback.
Topics: Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Dose-Response Relationship, Drug; Male; Models, Biological; Rats; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2011 |
Cilnidipine, but not amlodipine, ameliorates osteoporosis in ovariectomized hypertensive rats through inhibition of the N-type calcium channel.
Topics: Amlodipine; Animals; Antihypertensive Agents; Bone and Bones; Bone Density; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Female; Osteoporosis; Ovariectomy; Rats; Rats, Inbred SHR | 2012 |
Effects of cilnidipine on serum uric acid level and urinary nitrogen monoxide excretion in patients with hypertension.
Topics: Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Nitric Oxide; Treatment Outcome; Uric Acid | 2012 |
Comparison of the effects of cilnidipine and amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats.
Topics: Amlodipine; Animals; Blotting, Western; Calcium Channel Blockers; Diastole; Dihydropyridines; Immunohistochemistry; Male; Myocardium; Oxidative Stress; Rats; Rats, Inbred Dahl; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Additive effects of cilnidipine and angiotensin II receptor blocker in preventing the progression of diabetic nephropathy in diabetic spontaneously hypertensive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dihydropyridines; Disease Progression; Drug Therapy, Combination; Glomerulonephritis; Glucagon; Glucose Transporter Type 1; Glycated Hemoglobin; Glycogen; Hypertension; Kidney; Male; Norepinephrine; Proteinuria; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan | 2013 |
Involvement of N-type Ca(2+) channels in the fibrotic process of the kidney in rats.
Topics: Actins; Amlodipine; Animals; Cadherins; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cell Proliferation; Dihydropyridines; Disease Models, Animal; Epithelial-Mesenchymal Transition; Kidney; Macrophages; Male; Rats; Rats, Wistar; Ureteral Obstruction | 2013 |
Voltage-dependent N-type Ca2+ channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice.
Topics: Amlodipine; Angiotensin II; Animals; Aorta, Thoracic; Biomarkers; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemodynamics; Hypertension; Macrophages; Mice; omega-Conotoxin GVIA; Oxidative Stress; Reactive Oxygen Species; Vasodilation; Vasodilator Agents | 2013 |
Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Dihydropyridines; Drug Evaluation, Preclinical; Drug Therapy, Combination; Heart; Hypertension; Hypertrophy, Left Ventricular; Male; Myocytes, Cardiac; Oxidative Stress; Rats, Inbred Dahl; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Ventricular Remodeling | 2015 |
Cilnidipine but not amlodipine suppresses sympathetic activation elicited by isometric exercise in hypertensive patients.
Topics: Aged; Amlodipine; Autonomic Nervous System; Calcium Channel Blockers; Dihydropyridines; Exercise; Female; Hand Strength; Humans; Hypertension; Male; Middle Aged; Miosis; Mydriasis; Pupil; Reproducibility of Results | 2015 |
On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Valsartan | 2016 |
Cilnidipine: Next Generation Calcium Channel Blocker.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Humans; Hypertension; India; Middle Aged | 2016 |
Effects of L- and N-Type Ca Channel Blocker Cilnidipine on Changes in Heart Rate and QT Interval During Dialysis.
Topics: Aged; Amlodipine; Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Renal Dialysis; Sympathetic Nervous System | 2017 |
Comparison between L-type and N/L-type calcium channel blockers in the regulation of home blood-pressure variability in elderly hypertensive patients.
Topics: Aged; Amlodipine; Ankle Brachial Index; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Catecholamines; Dihydropyridines; Female; Humans; Hypertension; Male; Prospective Studies; Sympathetic Nervous System; Vascular Stiffness | 2018 |
Single-pill combination of cilnidipine, an L-/N-type calcium channel blocker, and valsartan effectively reduces home pulse pressure in patients with uncontrolled hypertension and sympathetic hyperactivity: The HOPE-Combi survey.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan | 2020 |
Comparison of effects of L/N-type and L-type calcium channel blockers on post-infarct cardiac remodelling in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Signaling; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hypertension; Male; Myocardial Infarction; Norepinephrine; Rats, Inbred SHR; Renin-Angiotensin System; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Single-pill combination of cilnidipine, an l-/n-type calcium channel blocker, and valsartan reduces the day-by-day variability of morning home systolic blood pressure in patients with treated hypertension: A sub-analysis of the HOPE-combi survey.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan | 2021 |
Cilnidipine for Amlodipine Induced Pedal Edema and its Anti-hypertensive Effect in a Tertiary Care Teaching Hospital of Western Nepal.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Edema; Hospitals, Teaching; Humans; Male; Middle Aged; Nepal; Prospective Studies; Tertiary Healthcare | 2021 |