amlodipine has been researched along with chlorthalidone in 117 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (2.56) | 18.2507 |
2000's | 55 (47.01) | 29.6817 |
2010's | 41 (35.04) | 24.3611 |
2020's | 18 (15.38) | 2.80 |
Authors | Studies |
---|---|
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Cutler, JA; Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; McDonald, R; Neaton, JD; Prineas, RJ; Schoenberger, JA; Stamler, J | 1 |
Elmer, PJ; Flack, J; Grandits, A; Lewis, CE; McDonald, R | 1 |
Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; Lewis, CE; Liebson, PR; McDonald, RH; Prineas, RJ; Svendsen, K; Yunis, C | 1 |
Schillaci, G; Verdecchia, P | 1 |
Black, H; Ghadanfar, M; Grimm, RH; Lewin, A; Rowen, R; Shi, H | 1 |
Düsing, R | 2 |
Nilsson, P | 1 |
Berglund, G; Håkansson, J; Hernborg, A; Werkö, L | 1 |
Traynor, K | 1 |
Wepner, U | 1 |
Vidt, DG | 1 |
Vetter, W | 1 |
Slany, J | 1 |
Rollins, G | 1 |
Scott, I; Stowasser, M | 1 |
Siragy, HM | 1 |
Messerli, FH; Weber, MA | 1 |
Ferdinand, KC | 1 |
Rahn, KH | 1 |
Kuwajima, I | 1 |
Leenen, FH | 1 |
Efstathiou, S; Makris, T; Manolis, A; Papavasiliou, M; Stergiou, GS | 1 |
Cushman, WC; Cutler, JA; Davis, BR; Dunn, JK; Ford, CE; Habib, GB; Haywood, LJ; Leenen, FH; Margolis, KL; Papademetriou, V; Probstfield, JL; Whelton, PK; Wright, JT | 1 |
Barzilay, J; Batuman, V; Davis, BR; Eckfeldt, JH; Farber, M; Henriquez, M; Kopyt, N; Louis, GT; Nwachuku, C; Pressel, S; Rahman, M; Saklayen, M; Stanford, C; Walworth, C; Ward, H; Whelton, PK; Wiegmann, T; Wright, JT | 1 |
Arnett, DK; Black, H; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Miller, MB | 2 |
Barzilay, J; Cushman, WC; Davis, BR; Iiamathi, E; Kostis, JB; Leenen, FH; Louis, GT; Margolis, KL; Mathis, DE; Moloo, J; Nwachuku, C; Panebianco, D; Parish, DC; Pressel, S; Simmons, DL; Thadani, U; Whelton, PK | 1 |
Barzilay, J; Batuman, V; Davis, BR; Eckfeldt, JH; Farber, MA; Franklin, S; Henriquez, M; Kopyt, N; Louis, GT; Nwachuku, C; Pressel, S; Rahman, M; Saklayen, M; Stanford, C; Walworth, C; Ward, H; Whelton, PK; Wiegmann, T; Wright, JT | 1 |
Hollenberg, NK | 1 |
Colon, P; Crow, R; Cutler, JA; Davis, BR; Dunn, K; Ellsworth, A; Franklin, S; Furberg, C; Goff, D; Golden, J; Leenen, F; Mohiuddin, S; Papademetriou, V; Piller, LB; Proschan, M | 1 |
González, AB; Hunziker, P; Jung, J; Marsch, S; Mehlig, A; Scholer, A; Vogt, S; Weinmann, W | 1 |
Black, HR; Davis, BR; Ford, CE; Nwachuku, C; Oparil, S; Piller, LB; Probstfield, JL; Retta, TM | 1 |
Barzilay, JI; Basile, J; Cutler, JA; Davis, BR; Margolis, KL; Ong, ST; Pressel, SL; Sadler, LS; Summerson, J; Whelton, PK | 1 |
Scarpello, JH; Tahrani, AA; Varughese, GI | 1 |
Alberici, M; Lembo, G; Payeras, AC; Sladek, K | 1 |
Christian, R; Colon, PJ; Cushman, WC; Einhorn, PT; Ford, CE; Goff, DC; Henriquez, MA; Margolis, KL; Piller, LB; Vidt, DG; Wong, ND; Wright, JT | 1 |
Baimbridge, C; Barzilay, J; Basile, J; Black, HR; Dart, RA; Davis, B; Marginean, H; Nwachuku, C; Thadani, U; Whelton, P; Wong, ND; Wright, JT | 1 |
Arnett, DK; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Lynch, AI | 3 |
Baimbridge, C; Bareis, CJ; Barzilay, J; Basile, JN; Black, HR; Dart, R; Davis, BR; Einhorn, PT; Gupta, AK; Hamilton, BP; Harris-Haywood, S; Haywood, LJ; Jafri, SZ; Louis, GT; Pressel, S; Scott, CL; Simmons, DL; Stanford, C; Whelton, PK; Wright, JT | 1 |
Cutler, JA; Davis, BR; Furberg, CD; Goldman, L; Heidenreich, PA; Lairson, DR; Nwachuku, C; Pressel, SL; Shlipak, MG | 1 |
Basile, JN; Bastien, A; Courtney, DL; Cushman, WC; Davis, BR; Einhorn, PT; Ford, CE; Hamilton, BP; Kirchner, K; Louis, GT; Preston, RA; Retta, TM; Vidt, DG; Weiss, RJ; Whelton, PK; Wright, JT | 1 |
Basile, JN; Carter, BL; Ernst, ME | 1 |
Parra, D; Rosenstein, R | 1 |
Arnett, DK; Barzilay, JI; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Irvin, MR; Kabagambe, EK; Lynch, AI; Tiwari, HK | 1 |
Alderman, MH; Calhoun, DA; Cushman, WC; Davis, BR; Eckfeldt, JH; Einhorn, PT; Ford, CE; Franklin, SS; Furberg, CD; Ong, ST; Oparil, S; Papademetriou, V; Piller, LB; Probstfield, JL | 1 |
Arnett, DK; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Lynch, AI; Zhang, X | 1 |
Baimbridge, C; Barzilay, JI; Brown, CD; Colon, PJ; Cutler, JA; Davis, BR; Fine, LJ; Ford, CE; Grimm, RH; Gupta, AK; Haywood, LJ; Henriquez, MA; Ilamaythi, E; Oparil, S; Piller, LB; Preston, R; Rahman, M; Whelton, PK; Wright, JT | 1 |
Sowers, JR; Whaley-Connell, A | 1 |
Alderman, MH; Blumenthal, SS; Castaldo, RS; Cushman, WC; Cutler, JA; Davis, BR; Ford, CE; Franklin, SS; Furberg, CD; Gordon, D; Graumlich, JF; Pavlik, V; Preston, RA; Proschan, M | 1 |
Bath, LE; Denvir, MA; Gebbie, A; Mirsadraee, S; Sule, AA; Turtle, EJ; Webb, DJ | 1 |
Cushman, WC; Davis, BR; Ford, CE; Furberg, CD; Habib, GB; Haywood, LJ; Margolis, K; Oparil, S; Probstfield, JL; Whelton, PK; Wright, JT | 1 |
Alderman, MH; Davis, BR; Einhorn, PT; Ford, CE; Furberg, CD; Grimm, RH; Jafri, SZ; Oparil, S; Phillips, W; Piller, LB; Probstfield, JL; Whittle, J; Williamson, JD | 1 |
Cichelero, FT; Fuchs, FD; Fuchs, SC; Gus, M; Martinez, D; Moreira, LB | 1 |
Jeffers, BW; Wang, JG; Yan, P | 1 |
Davis, BR; Kostis, JB; Levitan, EB; Lynch, AI; Muntner, P; Oparil, S; Simpson, LM; Whelton, PK; Whittle, J | 1 |
Barzilay, JI; Dart, RA; Davis, BR; Einhorn, PT; Graves, JW; Pressel, SL; Reisin, E; Retta, TM; Saklayen, MG; Yamal, JM | 1 |
Baraniuk, S; Basile, JN; Dart, RA; Davis, BR; Ellsworth, AJ; Fendley, H; Habib, GB; Piller, LB; Probstfield, JL; Rahman, M; Simpson, LM; Whelton, PK | 1 |
Arnett, DK; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Irvin, MR; Sørensen, IF; Sørensen, P; Vazquez, AI | 1 |
Alderman, MH; Calhoun, DA; Cushman, WC; Davis, BR; Fendley, HF; Franklin, SS; Habib, GB; Oparil, S; Pressel, SL; Probstfield, JL; Sastrasinh, S; Yamal, JM | 1 |
Davis, BR; Lynch, AI; Muntner, P; Oparil, S; Rahman, M; Simpson, LM; Tanner, RM; Whelton, PK; Whittle, J | 1 |
Albert, CM; Alonso, A; Davis, BR; Dewland, TA; Haywood, LJ; Magnani, JW; Marcus, GM; Piller, LB; Soliman, EZ; Yamal, JM | 1 |
Beard, BL; Davis, BR; Ford, CE; Hamilton, BP; Marginean, H; Probstfield, JL; Suhan, PS; Whittle, J; Williamson, JD; Yamal, JM | 1 |
Barzilay, JI; Cushman, WC; Davis, BR; Einhorn, PT; Ghosh, A; Louis, GT; Margolis, KL; Oparil, S; Pressel, SL; Puttnam, R; Whelton, PK; Williamson, J | 1 |
Cushman, WC; Davis, BR; Einhorn, PT; Ernst, ME; Ghosh, A; Grimm, RH; Okin, PM; Oparil, S; Prineas, RJ; Soliman, EZ | 1 |
Bangalore, S; Black, HR; Calhoun, DA; Cushman, WC; Davis, BR; Kostis, JB; Muntner, PM; Pressel, SL; Probstfield, JL; Rahman, M; Whelton, PK | 1 |
Hesselink, DA; Hoorn, EJ; Moes, AD; van den Meiracker, AH; Zietse, R | 1 |
Bang, CN; Davis, BR; Devereux, RB; Okin, PM; Simpson, LM; Soliman, EZ | 1 |
Coifman, RR; Coppi, AC; Davis, BR; Dhruva, SS; Furberg, CD; Huang, C; Krumholz, HM; Li, SX; Lin, H; Pressel, SL; Spatz, ES; Warner, F; Xu, X | 1 |
Chae, JK; Chae, SC; Chang, KY; Cho, JR; Choi, JH; Choi, YJ; Chun, KJ; Han, KR; Han, SH; Heo, JH; Hong, BK; Hong, SJ; Jeong, HS; Jeong, MH; Jung, J; Kang, HJ; Kang, SM; Kim, CH; Kim, DW; Kim, JJ; Kim, KS; Kim, SH; Kim, WS; Kim, YD; Kwan, J; Lee, BK; Lee, SK; Lee, SU; Park, CG; Park, SH; Shin, DG; Shin, JH; Won, KH | 1 |
Albert, CM; Alonso, A; Davis, BR; Dewland, TA; Haywood, LJ; Marcus, GM; Simpson, LM; Soliman, EZ; Yamal, JM | 1 |
Armario, P; Banegas, JR; de la Cruz, JJ; de la Sierra, A; Gorostidi, M; Oliveras, A; Ruilope, LM; Segura, J; Vinyoles, E | 1 |
Cho, HJ; Choi, DJ; Han, KR; Jo, SH; Kim, EJ; Kim, SJ; Park, JJ; Park, SJ; Shin, J; Shin, JH; Song, JM | 1 |
Cheriyan, J; Chowienczyk, PJ; Cockcroft, JR; Collier, D; Coulson, JM; Dasgupta, I; Faconti, L; Glover, M; Heagerty, AM; Khong, TK; Lip, GYH; Mander, AP; Marchong, MN; Martin, U; McDonnell, BJ; McEniery, CM; Mukhtar, O; Padmanabhan, S; Saxena, M; Sever, PJ; Shiel, JI; Wilkinson, IB; Wych, J | 1 |
Amarasekara, S; Amarasena, N; Billot, L; de Silva, AP; de Silva, HA; Fernando, M; Guggilla, R; Jan, S; Jayawardena, J; Maulik, PK; Mendis, S; Munasinghe, J; Naik, N; Patel, A; Prabhakaran, D; Rajapakse, S; Ranasinghe, G; Rodgers, A; Salam, A; Selak, V; Senaratne, V; Stepien, S; Thom, S; Tisserra, N; Webster, R; Wijekoon, S; Wijeyasingam, S | 1 |
Davis, BR; Einhorn, PT; Ford, CE; Ghosh, A; Haywood, LJ; Piller, LB; Probstfield, JL; Simpson, LM; Soliman, EZ; Wright, JT | 1 |
Arnett, DK; Barzilay, JI; Davis, BR; Lai, D; Pressel, S; Previn, HE | 1 |
Davis, BR; Johnson, K; Oparil, S; Tereshchenko, LG | 1 |
Beach, JL; Davis, BR; Ishak, A; Juraschek, SP; Mukamal, KJ; Simpson, LM | 1 |
Anireddy, J; Dongala, T; Palakurthi, AK; Yalavarthi, RK | 1 |
Beach, JL; Davis, BR; Ishak, A; Juraschek, SP; Mukamal, KJ; Shmerling, RH; Simpson, LM | 1 |
Billot, L; de Silva, A; Guggilla, R; Jan, S; Maulik, PK; Mysore, J; Naik, N; Patel, A; Prabhakaran, D; Rodgers, A; Salam, A; Selak, V; Stepien, S; Thom, S; Wang, N; Webster, R | 1 |
Hong, SJ; Kim, HY; Kim, SY; Kim, W; Lim, SW; Park, S; Rhee, MY; Shin, J; Sung, KC | 1 |
Cosgrove, NM; Dobrzynski, JM; Kostis, JB; Kostis, WJ; Moreyra, AE; Vakil, D; Zinonos, S | 1 |
Choi, Y; Chung, JY; Jeon, I; Jung, J; Moon, SJ; Park, SI; Yu, KS | 1 |
Chang, TI; Itoga, NK; Montez-Rath, ME; Tawfik, DS | 1 |
Bettencourt, JL; Davis, BR; Du, XL; Simpson, LM; Tandy, BC | 1 |
Agrawal, S; Anand, J; Bachani, D; Doshi, M; Gaikwad, VB; Halder, SK; Kinholkar, B; Kumar, DA; Kumbhar, A; Mathur, R; Mehta, S; Sarkar, G; Sharma, A | 1 |
de Silva, HA; Di Tanna, GL; Gnanenthiran, SR; Guggilla, R; Jan, S; Maulik, PK; Naik, N; Patel, A; Prabhakaran, D; Rodgers, A; Salam, A; Schutte, AE; Selak, V; Thom, S; Wang, N; Webster, R | 1 |
Patel, A; Prajapati, P; Shah, S | 1 |
Gongal, P; Hanna, JM; Nanna, MG; Onuma, OK; Wang, SY | 1 |
Ahn, JC; Cho, EJ; Han, SH; Kang, SM; Kim, KH; Kim, KI; Kim, SY; Kim, W; Kim, YJ; Park, CG; Park, SJ; Park, SM; Shin, J; Shin, JH; Sohn, IS; Sung, JH; Sung, KC | 1 |
Gnanenthiran, SR; Guggilla, RK; Maulik, PK; Patel, A; Rodgers, A; Salam, A; Schutte, AE; Selak, V; Silva, A; Webster, R | 1 |
Cazabon, D; Hering, D; Krishna, A; Moran, AE; Pathni, AK; Sahoo, SK; Sharma, B | 1 |
Cho, DK; Cho, GY; Cho, JM; Heo, JH; Hong, SJ; Jeong, MH; Jung, JA; Kim, DH; Kim, SH; Kim, SY; Kim, W; Kwon, K; Lee, HY; Lee, JB; Lim, SW; Park, K; Park, S; Pyun, WB; Rha, SW; Rhee, MY; Shin, J; Sung, KC | 1 |
Borges, RB; Cichelero, FT; Fuchs, FD; Fuchs, SC; Hirakata, VN; Jorge, JA; Lucca, MB; Martinez, D | 1 |
Ahn, Y; Cha, KS; Chang, K; Cho, EJ; Choi, DJ; Choi, SY; Doh, JH; Hong, SJ; Hong, SP; Hwang, JY; Hyon, MS; Ihm, SH; Kang, WC; Kim, HS; Kim, MH; Kim, SH; Kim, WS; Kim, YH; Kwon, K; Lee, JH; Lee, N; Lim, SW; Rhee, MY; Shin, J; Son, JW; Yoo, BS | 1 |
5 review(s) available for amlodipine and chlorthalidone
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Recommendations for the management of special populations: racial and ethnic populations.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black or African American; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Ramipril; Randomized Controlled Trials as Topic | 2003 |
[Recent intervention studies with antihypertensive drugs and their influence on guidelines].
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Clinical Trials as Topic; Death, Sudden, Cardiac; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Lisinopril; Meta-Analysis as Topic; Middle Aged; Myocardial Infarction; Practice Guidelines as Topic; Prognosis; Randomized Controlled Trials as Topic; Risk; Risk Factors; Sodium Chloride Symporter Inhibitors; Stroke; Time Factors | 2003 |
[ALLHAT trial--antithesis to the overuse of vasodilating antihypertensive drugs].
Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Doxazosin; Humans; Hypertension; Lisinopril; Male; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Stroke | 2004 |
Effects of amlodipine and other classes of antihypertensive drugs on long-term blood pressure variability: evidence from randomized controlled trials.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Enalapril; Humans; Hypertension; Lisinopril; Losartan; Randomized Controlled Trials as Topic | 2014 |
64 trial(s) available for amlodipine and chlorthalidone
Article | Year |
---|---|
Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.
Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Diastole; Double-Blind Method; Doxazosin; Echocardiography; Electrocardiography; Enalapril; Exercise; Female; Follow-Up Studies; Health Behavior; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Treatment Outcome | 1993 |
Efficacy and tolerance of antihypertensive treatment in men and women with stage 1 diastolic hypertension. Results of the Treatment of Mild Hypertension Study.
Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Doxazosin; Enalapril; Female; Humans; Hygiene; Hypertension; Life Style; Male; Middle Aged; Nutritional Physiological Phenomena; Patient Education as Topic; Severity of Illness Index; Treatment Outcome | 1996 |
Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS)
Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Double-Blind Method; Doxazosin; Enalapril; Female; Humans; Hypertension; Libido; Male; Middle Aged; Orgasm; Penile Erection; Sexual Dysfunction, Physiological | 1997 |
Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). ALLHAT Collaborative Research Group.
Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Diuretics; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Risk; Survival Analysis | 2000 |
Amlodipine versus chlorthalidone versus placebo in the treatment of stage I isolated systolic hypertension.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Treatment Outcome | 2002 |
Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Proportional Hazards Models; Risk Factors; Treatment Outcome | 2002 |
The ALLHAT Trial. Diuretics are still the preferred initial drugs for high blood pressure.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Determination; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Doxazosin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Male; Middle Aged; Patient Compliance; Probability; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2003 |
Are thiazide diuretics preferred as first-line therapy for hypertension? An appraisal of The Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Aged; Amlodipine; Benzothiadiazines; Blood Chemical Analysis; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Hypertrophy, Left Ventricular; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Myocardial Infarction; Queensland; Reference Values; Risk Assessment; Severity of Illness Index; Sodium Chloride Symporter Inhibitors; Stroke; Survival Analysis; Treatment Outcome | 2003 |
Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitors or calcium channel blocker vs diuretic. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Lisinopril; Male | 2003 |
Comparison of antihypertensive effects of an angiotensin-converting enzyme inhibitor, a calcium antagonist and a diuretic in patients with hypertension not controlled by angiotensin receptor blocker monotherapy.
Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Renal outcomes in high-risk hypertensive patients treated with an angiotensin-converting enzyme inhibitor or a calcium channel blocker vs a diuretic: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Incidence; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Patient Compliance; Risk Factors; Treatment Outcome | 2005 |
Pharmacogenetic association of the angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure and cardiovascular risk in relation to antihypertensive treatment: the Genetics of Hypertension-Associated Treatment (GenHAT) study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Double-Blind Method; Doxazosin; Female; Follow-Up Studies; Genotype; Humans; Lisinopril; Male; Middle Aged; Peptidyl-Dipeptidase A; Pharmacogenetics; Polymorphism, Genetic; Predictive Value of Tests; Proportional Hazards Models; Risk Factors; Treatment Outcome | 2005 |
Clinical outcomes in antihypertensive treatment of type 2 diabetes, impaired fasting glucose concentration, and normoglycemia: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Glucose; Chlorthalidone; Coronary Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypoglycemia; Lisinopril; Male; Middle Aged; Treatment Outcome | 2005 |
Cardiovascular outcomes in high-risk hypertensive patients stratified by baseline glomerular filtration rate.
Topics: Aged; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Chronic Disease; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Risk Factors | 2006 |
Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Chlorthalidone; Diuretics; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Female; Heart Failure; Hospitalization; Humans; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Risk; Treatment Outcome | 2006 |
Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Chlorthalidone; Coronary Disease; Double-Blind Method; Doxazosin; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Hypertension; Incidence; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Patient Selection; Polymorphism, Genetic; Proportional Hazards Models; Risk Assessment; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Tryptophan | 2007 |
Incidence and predictors of angioedema in elderly hypertensive patients at high risk for cardiovascular disease: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Aged; Aged, 80 and over; Amlodipine; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Canada; Cardiovascular Diseases; Chlorthalidone; Female; Humans; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Prognosis; Risk Factors; Time Factors; United States | 2006 |
Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults randomized to receive 3 different classes of antihypertensive treatment: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHA
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Chi-Square Distribution; Chlorthalidone; Diabetes Mellitus; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Sodium Chloride Symporter Inhibitors; Treatment Outcome | 2006 |
Antihypertensive efficacy and safety of manidipine versus amlodipine in elderly subjects with isolated systolic hypertension: MAISH study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Dihydropyridines; Diuretics; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; Hypertension; Male; Middle Aged; Nitrobenzenes; Piperazines; Risk Assessment; Risk Factors; Systole; Time Factors; Treatment Outcome | 2007 |
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthalidone; Clonidine; Double-Blind Method; Doxazosin; Female; Heart Diseases; Hispanic or Latino; Humans; Hydralazine; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Puerto Rico; Reserpine; Treatment Outcome; United States; United States Virgin Islands; White People | 2007 |
Clinical outcomes by race in hypertensive patients with and without the metabolic syndrome: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Black People; Chlorthalidone; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Lisinopril; Male; Metabolic Syndrome; Middle Aged; Treatment Outcome; White People | 2008 |
Cost-effectiveness of chlorthalidone, amlodipine, and lisinopril as first-step treatment for patients with hypertension: an analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Chlorthalidone; Cost-Benefit Analysis; Diuretics; Female; Humans; Hypertension; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Myocardial Infarction; Quality-Adjusted Life Years | 2008 |
Blood pressure control by drug group in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Diuretics; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Logistic Models; Male; Middle Aged; Treatment Outcome | 2008 |
Antihypertensive pharmacogenetic effect of fibrinogen-beta variant -455G>A on cardiovascular disease, end-stage renal disease, and mortality: the GenHAT study.
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Fibrinogen; Genetic Variation; Genotype; Humans; Hypertension; Kidney Failure, Chronic; Lisinopril; Middle Aged; Stroke; Treatment Outcome | 2009 |
Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study.
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Chlorthalidone; Diabetes Mellitus; Diuretics; Double-Blind Method; Epithelial Sodium Channels; Fasting; Female; Humans; Hypertension; Lisinopril; Longitudinal Studies; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors; Treatment Outcome | 2010 |
Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Coronary Disease; Doxazosin; Female; Follow-Up Studies; Genetic Association Studies; Genotype; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Polymorphism, Genetic; Proportional Hazards Models; Risk Factors; Treatment Outcome | 2012 |
Clinical significance of incident hypokalemia and hyperkalemia in treated hypertensive patients in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Chemical Analysis; Cardiovascular Diseases; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hyperkalemia; Hypertension; Hypokalemia; Incidence; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Prospective Studies; Risk Assessment; Survival Rate; Treatment Outcome | 2012 |
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study.
Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-Blind Method; Female; Follow-Up Studies; Genotype; Heart Failure; Humans; Hypertension; Lisinopril; Male; Middle Aged; Nitric Oxide Synthase Type III; Polymorphism, Single Nucleotide; Risk Factors; Stroke | 2012 |
Long-term renal and cardiovascular outcomes in Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) participants by baseline estimated GFR.
Topics: Amlodipine; Antihypertensive Agents; Canada; Chlorthalidone; Chronic Disease; Coronary Disease; Double-Blind Method; Female; Glomerular Filtration Rate; Heart Failure; Humans; Hypertension; Hypolipidemic Agents; Incidence; Kaplan-Meier Estimate; Kidney; Kidney Diseases; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Proportional Hazards Models; Puerto Rico; Risk Assessment; Risk Factors; Severity of Illness Index; Stroke; Time Factors; Treatment Outcome; United States; United States Virgin Islands | 2012 |
Mortality and morbidity during and after Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial: results by sex.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Female; Follow-Up Studies; Heart Failure; Humans; Hypertension; Hypolipidemic Agents; Incidence; Lisinopril; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Risk Factors; Sex Factors; Stroke | 2013 |
Risk of hospitalized gastrointestinal bleeding in persons randomized to diuretic, ACE-inhibitor, or calcium-channel blocker in ALLHAT.
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Diuretics; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Myocardial Infarction; Risk Factors; Treatment Outcome | 2013 |
The effect of antihypertensive agents on sleep apnea: protocol for a randomized controlled trial.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Clinical Protocols; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Polysomnography; Research Design; Sleep; Sleep Apnea Syndromes; Time Factors; Treatment Outcome | 2014 |
Effect of chlorthalidone, amlodipine, and lisinopril on visit-to-visit variability of blood pressure: results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
Topics: Acute Coronary Syndrome; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Calcium Channel Blockers; Chlorthalidone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Office Visits; Prognosis; Risk Factors; Treatment Outcome | 2014 |
Blood pressure control and cardiovascular outcomes in normal-weight, overweight, and obese hypertensive patients treated with three different antihypertensives in ALLHAT.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Cohort Studies; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Obesity; Overweight; Prospective Studies | 2014 |
Characteristics and long-term follow-up of participants with peripheral arterial disease during ALLHAT.
Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Peripheral Arterial Disease; United States | 2014 |
Stroke outcomes among participants randomized to chlorthalidone, amlodipine or lisinopril in ALLHAT.
Topics: Age Factors; Aged; Amlodipine; Cause of Death; Chlorthalidone; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Proportional Hazards Models; Risk Assessment; Severity of Illness Index; Sex Factors; Stroke; Survival Rate; Treatment Outcome | 2014 |
Effect of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) on Conduction System Disease.
Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Electrocardiography; Female; Heart Conduction System; Humans; Lisinopril; Male; Middle Aged; Prognosis | 2016 |
Clinical and demographic correlates of medication and visit adherence in a large randomized controlled trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Appointments and Schedules; Black People; Chlorthalidone; Demography; Double-Blind Method; Female; Humans; Hypertension; Lisinopril; Male; Medication Adherence; Middle Aged; Myocardial Infarction; North America; Patient Compliance; Retrospective Studies; Treatment Outcome | 2016 |
Association of 3 Different Antihypertensive Medications With Hip and Pelvic Fracture Risk in Older Adults: Secondary Analysis of a Randomized Clinical Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Female; Follow-Up Studies; Hip Fractures; Humans; Intention to Treat Analysis; Lisinopril; Male; Pelvic Bones; Risk Assessment; Risk Factors; United States | 2017 |
Electrocardiographic measures of left ventricular hypertrophy in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Electrocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Hypolipidemic Agents; Incidence; Lipids; Lisinopril; Male; Middle Aged; Myocardial Infarction; Prevalence; Risk Factors | 2016 |
Treatment-Resistant Hypertension and Outcomes Based on Randomized Treatment Group in ALLHAT.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Treatment Failure; Treatment Outcome | 2017 |
Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Cross-Over Studies; Edema; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Proteinuria; Tacrolimus; Treatment Outcome | 2017 |
Electrocardiographic Left Ventricular Hypertrophy Predicts Cardiovascular Morbidity and Mortality in Hypertensive Patients: The ALLHAT Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cause of Death; Chlorthalidone; Disease Progression; Electrocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Male; Middle Aged; Predictive Value of Tests; Risk Factors; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2017 |
Heterogeneity in Early Responses in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial).
Topics: Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Doxazosin; Drug Monitoring; Female; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Treatment Outcome | 2017 |
Comparison of Fixed-dose Combinations of Amlodipine/Losartan Potassium/Chlorthalidone and Amlodipine/Losartan Potassium in Patients With Stage 2 Hypertension Inadequately Controlled With Amlodipine/Losartan Potassium: A Randomized, Double-blind, Multicent
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Young Adult | 2017 |
Pharmacologic Prevention of Incident Atrial Fibrillation: Long-Term Results From the ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial).
Topics: Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Atrial Flutter; Chlorthalidone; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Incidence; Lisinopril; Male; Middle Aged; Myocardial Infarction; Primary Prevention; Risk Factors; Time Factors; Treatment Outcome; United States | 2017 |
S-amlodipine plus chlorthalidone vs. S-amlodipine plus telmisartan in hypertensive patients unresponsive to amlodipine monotherapy: study protocol for a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Clinical Trials, Phase IV as Topic; Diuretics; Double-Blind Method; Drug Combinations; Drug Resistance; Equivalence Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Republic of Korea; Telmisartan; Time Factors; Treatment Outcome; Young Adult | 2018 |
A randomized controlled crossover trial evaluating differential responses to antihypertensive drugs (used as mono- or dual therapy) on the basis of ethnicity: The comparIsoN oF Optimal Hypertension RegiMens; part of the Ancestry Informative Markers in HYp
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Asian People; Black People; Chlorthalidone; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Lisinopril; Middle Aged; Prospective Studies; United Kingdom; White People; Young Adult | 2018 |
Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Potassium; Sri Lanka; Telmisartan | 2018 |
Risk Factors Influencing Outcomes of Atrial Fibrillation in ALLHAT.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Atrial Flutter; Chlorthalidone; Coronary Disease; Double-Blind Method; Female; Heart Failure; Humans; Hypertension; Lisinopril; Male; Myocardial Infarction; Proportional Hazards Models; Risk Factors; Stroke | 2018 |
The Interaction of a Diabetes Gene Risk Score With 3 Different Antihypertensive Medications for Incident Glucose-level Elevation.
Topics: Alkadienes; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Calcium Channel Blockers; Chlorthalidone; Diabetes Mellitus; Female; Gene Frequency; Genetic Testing; Genotype; Humans; Hypertension; Lisinopril; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; Sodium Chloride Symporter Inhibitors | 2019 |
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Linear Models; Lisinopril; Logistic Models; Male; Middle Aged; Personal Protective Equipment; Proportional Hazards Models | 2019 |
Association of Low-Dose Triple Combination Therapy With Therapeutic Inertia and Prescribing Patterns in Patients With Hypertension: A Secondary Analysis of the TRIUMPH Trial.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Drug Prescriptions; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Telmisartan; Treatment Outcome | 2020 |
Low-Dose Triple Antihypertensive Combination Therapy in Patients with Hypertension: A Randomized, Double-Blind, Phase II Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged | 2020 |
Monotherapy treatment with chlorthalidone or amlodipine in the systolic blood pressure intervention trial (SPRINT).
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Humans; Hypertension; Treatment Outcome | 2021 |
Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan and Chlorthalidone Compared to Concurrent Administration of the Separate Components.
Topics: Amlodipine; Chlorthalidone; Cross-Over Studies; Drug Combinations; Humans; Losartan | 2022 |
Risk of hospitalized and non-hospitalized gastrointestinal bleeding in ALLHAT trial participants receiving diuretic, ACE-inhibitor, or calcium-channel blocker.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium; Calcium Channel Blockers; Chlorthalidone; Diuretics; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Risk Factors; United States | 2021 |
Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Coronary Artery Disease; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metoprolol; Telmisartan; Tetrazoles | 2022 |
Association of Low-Dose Triple Combination Therapy vs Usual Care With Time at Target Blood Pressure: A Secondary Analysis of the TRIUMPH Randomized Clinical Trial.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged | 2022 |
Efficacy and safety of low-dose antihypertensive combination of amlodipine, telmisartan, and chlorthalidone: A randomized, double-blind, parallel, phase II trial.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Essential Hypertension; Humans; Hypertension; Telmisartan; Treatment Outcome | 2022 |
Reduced efficacy of blood pressure lowering drugs in the presence of diabetes mellitus-results from the TRIUMPH randomised controlled trial.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diabetes Mellitus; Drug Combinations; Humans; Hypertension | 2023 |
Comparison of efficacy and safety between third-dose triple and third-dose dual antihypertensive combination therapies in patients with hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Hypotension; Losartan; Treatment Outcome | 2023 |
Effects of chlorthalidone plus amiloride compared with amlodipine on short-term blood pressure variability in individuals with hypertension and obstructive sleep apnea: a randomized controlled trial.
Topics: Adult; Amiloride; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged; Sleep Apnea, Obstructive | 2023 |
Efficacy and safety of standard dose triple combination of telmisartan 80 mg/amlodipine 5 mg/chlorthalidone 25 mg in primary hypertension: A randomized, double-blind, active-controlled, multicenter phase 3 trial.
Topics: Aged; Amlodipine; Chlorthalidone; Essential Hypertension; Female; Humans; Hypertension; Leukemia, Myeloid, Acute; Male; Middle Aged; Telmisartan | 2023 |
48 other study(ies) available for amlodipine and chlorthalidone
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Are all antihypertensive agents equal? Cardiovascular events in hypertensive patients randomized to treatment with doxazosin or chlorthalidone. The ALLHAT study].
Topics: Adrenergic alpha-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Canada; Chlorthalidone; Coronary Disease; Diuretics; Doxazosin; Humans; Hypertension; Lisinopril; Multicenter Studies as Topic; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk; United States | 2000 |
[Old or new antihypertensive drugs? Consequences from ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial].
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Diuretics; Doxazosin; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Research Design; Treatment Outcome | 2003 |
[ALLHAT--the most comprehensive antihypertensive treatment trial in the world. The significance of thiazide diuretics for patients older than 55 years is confirmed].
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Sodium Chloride Symporter Inhibitors | 2003 |
[Consequences of ALLHAT: Thiazides rehabilitated--time to change prescription patterns].
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Chlorthalidone; Cost Savings; Diuretics; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Practice Patterns, Physicians'; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors | 2003 |
ALLHAT finds diuretics best for initial hypertension therapy.
Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Lisinopril; Myocardial Infarction | 2003 |
Diuretics: first choice for treating high BP.
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Lisinopril; Middle Aged | 2003 |
[Established blood pressure drug wins out in a comparative study. In hypertension, a diuretic first!].
Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Chlorthalidone; Coronary Disease; Diuretics; Double-Blind Method; Doxazosin; Humans; Hypertension; Lisinopril; Middle Aged; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors | 2003 |
Hats off to an old blood pressure drug. For treating high blood pressure, an old--and inexpensive--medication is a great place to start or a good one to add.
Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Lisinopril | 2003 |
[What are the sequelae of the ALLHAT Study?].
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Critical Pathways; Humans; Hypertension; Lisinopril; Randomized Controlled Trials as Topic | 2003 |
Diuretics: older, cheaper, better.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzothiadiazines; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Diuretics; Doxazosin; Humans; Hypertension; Lisinopril; Middle Aged; Sodium Chloride Symporter Inhibitors | 2003 |
[ALLHAT: Old Hat Hits All? On selection of the optimal antihypertensive drug].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cause of Death; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Long-Term Care; Male; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome | 2003 |
Diuretics are better first-line antihypertensive therapy than calcium channel blockers and ACE inhibitors.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Humans; Hypertension; Lisinopril; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome; United States | 2003 |
A cheaper way to control high blood pressure.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Diuretics; Humans; Hypertension; Lisinopril | 2003 |
ALLHAT--all hit or all miss? Key questions still remain.
Topics: Amlodipine; Antihypertensive Agents; Black People; Chlorthalidone; Humans; Hypolipidemic Agents; Lisinopril; Myocardial Infarction; Research Design; Survival Analysis; White People | 2003 |
[The new (old) knowledge in primary prevention of stroke. It depends on lowering of blood pressure].
Topics: Adrenergic alpha-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black or African American; Calcium Channel Blockers; Chlorthalidone; Clinical Trials as Topic; Doxazosin; Follow-Up Studies; Heart Failure; Humans; Lisinopril; Middle Aged; Myocardial Infarction; Primary Prevention; Stroke; Time Factors | 2003 |
ALLHAT: what has it taught us so far?
Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Humans; Hypertension; Lisinopril; Myocardial Infarction; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic | 2004 |
Outcomes in hypertensive black and nonblack patients treated with chlorthalidone, amlodipine, and lisinopril.
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Humans; Hypertension; Lisinopril; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome | 2005 |
Summaries for patients. Do the effects of blood pressure drugs differ by kidney function?
Topics: Aged; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Chronic Disease; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Risk Factors | 2006 |
Omission of drug dose information.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalidone; Dose-Response Relationship, Drug; Humans; Hypertension; Lisinopril; Randomized Controlled Trials as Topic | 2006 |
Survival of severe amlodipine intoxication due to medical intensive care.
Topics: Adult; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Chlorthalidone; Critical Care; Diuretics; Drug Overdose; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Male; Mefenamic Acid; Suicide, Attempted | 2006 |
Blood pressure drugs can boost blood sugar. Depending on the drug, though, it may not matter.
Topics: Amlodipine; Antihypertensive Agents; Blood Glucose; Chlorthalidone; Clinical Trials as Topic; Diabetes Mellitus; Diuretics; Humans; Lisinopril | 2007 |
The putative link between glycemic control and cardiac arrhythmias.
Topics: Amlodipine; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Glucose; Chlorthalidone; Diabetes Mellitus; Diuretics; Humans; Hypertension; Lisinopril | 2007 |
Metabolic and clinical outcomes in nondiabetic individuals with the metabolic syndrome assigned to chlorthalidone, amlodipine, or lisinopril as initial treatment for hypertension: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent
Topics: Aged; Amlodipine; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Chlorthalidone; Cohort Studies; Coronary Disease; Female; Humans; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Metabolic Syndrome; Middle Aged; Myocardial Infarction; Risk Factors | 2008 |
Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Diuretics; Doxazosin; Female; Genotype; Humans; Hypertension; Lisinopril; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide | 2008 |
All thiazide-like diuretics are not chlorthalidone: putting the ACCOMPLISH study into perspective.
Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 2009 |
Benazepril plus amlodipine or hydrochlorothiazide for hypertension.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia | 2009 |
Strengthening diuretics' role in hypertension.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Chlorthalidone; Diuretics; Humans; Hypertension; Lisinopril | 2010 |
Initial choice of antihypertensive on long-term cardiovascular outcomes in CKD.
Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypolipidemic Agents; Kidney; Kidney Diseases; Lisinopril; Male; Myocardial Infarction | 2012 |
How much effect of different antihypertensive medications on cardiovascular outcomes is attributable to their effects on blood pressure?
Topics: Amlodipine; Antihypertensive Agents; Biostatistics; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Coronary Disease; Endpoint Determination; Heart Failure; Humans; Hypertension; Lisinopril; Myocardial Infarction; Randomized Controlled Trials as Topic; Regression Analysis; Treatment Outcome | 2013 |
Lessons from a patient with Turner syndrome.
Topics: Amlodipine; Blood Pressure; Chlorthalidone; Estrogens; Female; Hormone Replacement Therapy; Humans; Hypertension; Life Expectancy; Progestins; Turner Syndrome; Young Adult | 2013 |
Pharmacogenetic effects of 'candidate gene complexes' on stroke in the GenHAT study.
Topics: Aged; Amlodipine; Chlorthalidone; Female; Genotype; Humans; Lisinopril; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Stroke | 2014 |
Visit-to-Visit Variability of BP and CKD Outcomes: Results from the ALLHAT.
Topics: Aged; Amlodipine; Antihyperkalemic Agents; Blood Pressure; Blood Pressure Determination; Chlorthalidone; Disease Progression; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Risk Factors; Time Factors; Treatment Outcome | 2016 |
Antihypertensive drug use in resistant and nonresistant hypertension and in controlled and uncontrolled resistant hypertension.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Mineralocorticoid Receptor Antagonists; Ramipril; Tetrazoles | 2018 |
Effects of Antihypertensive Class on Falls, Syncope, and Orthostatic Hypotension in Older Adults: The ALLHAT Trial.
Topics: Accidental Falls; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Atenolol; Chlorthalidone; Female; Humans; Hypertension; Hypotension, Orthostatic; Incidence; Male; Medicare; Syncope; Treatment Outcome; United States | 2019 |
QbD-based development of an extraction procedure for simultaneous quantification of telmisartan, amlodipine besylate and chlorthalidone in combination complex matrix formulation.
Topics: Amlodipine; Chlorthalidone; Chromatography, High Pressure Liquid; Drug Combinations; Limit of Detection; Linear Models; Reproducibility of Results; Research Design; Tablets; Telmisartan | 2020 |
The effects of antihypertensive class on gout in older adults: secondary analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Female; Gout; Humans; Hypertension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Treatment Outcome | 2020 |
Contributions of Systolic and Diastolic Blood Pressures to Cardiovascular Outcomes in the ALLHAT Study.
Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Chlorthalidone; Diastole; Female; Follow-Up Studies; Heart Failure; Humans; Lisinopril; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Risk Assessment; Risk Factors; Stroke; Systole | 2021 |
Simultaneous Estimation of Telmisartan, Chlorthalidone, Amlodipine Besylate and Atorvastatin by RP-HPLC Method for Synchronous Assay of Multiple FDC Products Using Analytical FMCEA-Based AQbD Approach.
Topics: Amlodipine; Atorvastatin; Chlorthalidone; Chromatography, High Pressure Liquid; Telmisartan | 2023 |
Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial.
Topics: Amlodipine; Antihypertensive Agents; Chlorthalidone; Humans; Hypertension; Isolated Systolic Hypertension; Lisinopril; Treatment Outcome | 2022 |
Financial implications of protocol-based hypertension treatment: an insight into medication costs in public and private health sectors in India.
Topics: Amlodipine; Chlorthalidone; Humans; Hypertension; India; Private Sector; Telmisartan | 2023 |