amlodipine and captopril

amlodipine has been researched along with captopril in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.76)18.7374
1990's7 (16.67)18.2507
2000's20 (47.62)29.6817
2010's13 (30.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lacourcière, Y; Poirier, L; Provencher, P2
Guevara, J; Hernández, O; Hernández, R; Urbina, A; Velasco, M1
Maclean, D; Mitchell, ET; Tyler, HM; Walker, P; Wilcox, RG2
Bueno, JM; Marco, MD; Pertusa, S; Quirce, F1
Maclean, D1
Atarashi, K; Ishiyama, A; Minami, M; Takagi, M1
Hayashi, K; Kumagai, H; Kumamaru, H; Saruta, T1
Barretto, OC; Dantas de Medeiros, TM; Mion, D; Nonoyama, K; Ortega, KC1
Studney, D1
Bertocchi, F; Carretta, R; Di Somma, S; Malacco, E; Mugellini, A; Palatini, P; Piazza, S1
Suzuki, H1
Inomata, K; Tanaka, H1
Ghini, B; Lehfeld, LS; Lopes de Faria, JB; Silveira, LA1
Oron-Herman, M; Rosenthal, T; Sela, BA1
Ackerman, Z; Grozovski, M; Link, G; Oron-Herman, M; Pappo, O; Rosenthal, T; Sela, BA2
Tan, J; Wei, L1
Fonseca, R; Guevara, J; Hernandez, R; Pieretti, OH; Silva, H; Urbina, A; Velasco, M1
Bertoluci, MC; Oliveira, FR; Schmid, H; Schmidt, A; Thomazelli, FC; Uebel, D1
Feely, J; Mahmud, A1
Farsang, C1
Chernin, G; Francis, M; Heeringa, SF; Soliman, NA1
Hosseini, F; Mahmoudian, M; Nemati, F; Rahbar-Roshandel, N; Shafiei, M1
Bolen, MA; Halliburton, SS; Schoenhagen, P1
Purnamasari, D; Soebijanto, N1
Ackerman, Z; Amir, G; Grozovski, M; Oron-Herman, M; Rosenthal, T; Sela, BA1
Ali, SN; Arayne, MS; Sultana, N1
Alves, PH; Castro, CH; Colugnati, DB; Macedo, LM; Mendes, EP; Nunes, AD; Pedrino, GR; Santos, RA; Souza, AP1
Ambrosioni, E; Bacchelli, S; Borghi, C; Degli Esposti, D; Omboni, S; Reggiardo, G1
Habara, M; Haraguchi, T; Ikezaki, H; Kojima, H; Nakamura, S; Uchida, T; Yoshida, M1

Reviews

3 review(s) available for amlodipine and captopril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Angiotensin blockade in type 2 diabetes: what the new evidence tells us about renal and cardiac complications.
    The Canadian journal of cardiology, 2002, Volume: 18 Suppl A

    Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Humans; Irbesartan; Kidney Diseases; Losartan; Prognosis; Ramipril; Tetrazoles

2002
[Evidence for the benefits of ACE inhibitors and AII antagonists in slowing progressive renal failure in diabetes].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 10

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Captopril; Clinical Trials as Topic; Disease Progression; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Tetrazoles; Treatment Outcome

2002

Trials

13 trial(s) available for amlodipine and captopril

ArticleYear
Comparison of the effects of amlodipine and captopril on clinic and ambulatory blood pressure.
    Journal of human hypertension, 1992, Volume: 6 Suppl 1

    Topics: Adult; Ambulatory Care; Amlodipine; Blood Pressure; Captopril; Circadian Rhythm; Clinical Protocols; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Single-Blind Method; Time Factors

1992
A double-blind, parallel, comparative evaluation of amlodipine against captopril in the monotherapeutic treatment of mild and moderate essential hypertension: interim results.
    Postgraduate medical journal, 1991, Volume: 67 Suppl 5

    Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine

1991
A double-blind crossover comparison of amlodipine and placebo added to captopril in moderate to severe hypertension.
    Journal of cardiovascular pharmacology, 1988, Volume: 12 Suppl 7

    Topics: Adolescent; Adult; Aged; Amlodipine; Calcium Channel Blockers; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation

1988
Comparison of amlodipine and captopril in hypertension based on 24-hour ambulatory monitoring.
    Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl A

    Topics: Adult; Aged; Ambulatory Care; Amlodipine; Blood Pressure; Blood Pressure Determination; Captopril; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic

1993
Combination therapy with amlodipine and captopril for resistant systemic hypertension.
    The American journal of cardiology, 1994, Jan-27, Volume: 73, Issue:3

    Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Captopril; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Research Design

1994
Amlodipine is comparable to angiotensin-converting enzyme inhibitor for long-term renoprotection in hypertensive patients with renal dysfunction: a one-year, prospective, randomized study.
    American journal of hypertension, 2000, Volume: 13, Issue:9

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Chronic Disease; Enalapril; Female; Glomerulonephritis; Humans; Hypertension; Kidney; Male; Middle Aged; Prospective Studies; Time Factors

2000
Comparison of benazepril-amlodipine and captopril-thiazide combinations in the management of mild-to-moderate hypertension.
    International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:6

    Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Captopril; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

2002
Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment.
    Chinese journal of integrative medicine, 2005, Volume: 11, Issue:1

    Topics: Adult; Aged; Albuminuria; Amlodipine; Antihypertensive Agents; beta 2-Microglobulin; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Flavonoids; Flushing; Humans; Hypertension; Injections, Intravenous; Kidney Diseases; Male; Middle Aged; Proteinuria

2005
A double-blind, parallel, comparative evaluation of amlodipine vs. captopril in the monotherapeutic treatment of mild and moderate essential hypertension.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Captopril; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Severity of Illness Index

1991
Urinary TGF-beta1 reduction related to a decrease of systolic blood pressure in patients with type 2 diabetes and clinical diabetic nephropathy.
    Diabetes research and clinical practice, 2006, Volume: 72, Issue:3

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Captopril; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propranolol; Ramipril; Transforming Growth Factor beta1

2006
Low-dose quadruple antihypertensive combination: more efficacious than individual agents--a preliminary report.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:2

    Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Capsules; Captopril; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged

2007
Blood pressure control and response rates with zofenopril compared with amlodipine in hypertensive patients.
    Blood pressure. Supplement, 2007, Volume: 2

    Topics: Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Treatment Outcome

2007
Efficacy of zofenopril in combination with amlodipine in patients with acute myocardial infarction: a pooled individual patient data analysis of four randomized, double-blind, controlled, prospective studies.
    Current medical research and opinion, 2018, Volume: 34, Issue:10

    Topics: Aged; Amlodipine; Antihypertensive Agents; Captopril; Data Analysis; Double-Blind Method; Female; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Time-to-Treatment; Treatment Outcome

2018

Other Studies

26 other study(ies) available for amlodipine and captopril

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Amlodipine and captopril in moderate-severe essential hypertension.
    Journal of human hypertension, 1988, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Aged; Amlodipine; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation

1988
[Sexual dysfunction due to captopril and amlodipine].
    Atencion primaria, 1994, Apr-15, Volume: 13, Issue:6

    Topics: Aged; Amlodipine; Captopril; Erectile Dysfunction; Humans; Hypertension; Male

1994
Effects of alacepril and amlodipine on the renal injury induced by a high-cholesterol diet in rats.
    Journal of hypertension, 1999, Volume: 17, Issue:12 Pt 2

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Captopril; Cholesterol, Dietary; Kidney; Kidney Diseases; Lipids; Male; Proteinuria; Rats; Rats, Sprague-Dawley

1999
Normal erythrocyte calpain I activity on membrane proteins under near-physiological conditions in patients with essential hypertension.
    Sao Paulo medical journal = Revista paulista de medicina, 2002, Jan-03, Volume: 120, Issue:1

    Topics: Adult; Amlodipine; Ankyrins; Calcium-Binding Proteins; Calpain; Captopril; Case-Control Studies; Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Humans; Hypertension; Membrane Proteins

2002
Protective effect of benidipine against sodium azide-induced cell death in cultured neonatal rat cardiac myocytes.
    Journal of pharmacological sciences, 2003, Volume: 93, Issue:2

    Topics: Adenosine Triphosphate; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Cell Death; Cells, Cultured; Cysteine Proteinase Inhibitors; Dihydropyridines; Dipeptides; Dose-Response Relationship, Drug; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria, Muscle; Myocytes, Cardiac; Nifedipine; Rats; Rats, Sprague-Dawley; Sodium Azide; Tetrazoles

2003
Early blood pressure normalization independent of the class of antihypertensive agent prevents augmented renal fibronectin and albuminuria in experimental diabetic nephropathy.
    Kidney & blood pressure research, 2004, Volume: 27, Issue:2

    Topics: Albuminuria; Amlodipine; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Synergism; Fibronectins; Glomerular Filtration Rate; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Verapamil

2004
Risk reduction therapy for syndrome X: comparison of several treatments.
    American journal of hypertension, 2005, Volume: 18, Issue:3

    Topics: Amlodipine; Animals; Antihypertensive Agents; Bezafibrate; Blood Pressure; Body Weight; Captopril; Fructose; Hydrolases; Hypertension; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Male; Metabolic Syndrome; Rats; Rats, Sprague-Dawley; Risk Reduction Behavior; Rosiglitazone; Thiazolidinediones; Triglycerides

2005
Fructose-induced fatty liver disease: hepatic effects of blood pressure and plasma triglyceride reduction.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:5

    Topics: Amlodipine; Animals; Antihypertensive Agents; Bezafibrate; Blood Pressure; Captopril; Diet; Fatty Liver; Fructose; Hypolipidemic Agents; Iron; Liver; Male; Rats; Rats, Sprague-Dawley; Triglycerides

2005
Effects of amlodipine, captopril, and bezafibrate on oxidative milieu in rats with fatty liver.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:3

    Topics: Amlodipine; Animals; Antihypertensive Agents; Bezafibrate; Captopril; Fatty Liver; Fructose; Hypolipidemic Agents; Male; Metabolic Syndrome; Oxidative Stress; Rats; Rats, Sprague-Dawley

2008
Complete remission of nephrotic syndrome in an infant with focal segmental glomerulosclerosis: is it renin-angiotensin blockade?
    Pediatric nephrology (Berlin, Germany), 2009, Volume: 24, Issue:5

    Topics: Albumins; Amlodipine; Angiotensins; Antihypertensive Agents; Captopril; Drug Resistance; Drug Therapy, Combination; Furosemide; Glomerulosclerosis, Focal Segmental; Humans; Infant; Labetalol; Male; Nephrotic Syndrome; Prednisolone; Remission Induction; Renin-Angiotensin System

2009
Anti-inflammatory effects of anti-hypertensive agents: influence on interleukin-1β secretion by peripheral blood polymorphonuclear leukocytes from patients with essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2011, Volume: 33, Issue:2

    Topics: Adult; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Atenolol; Captopril; Case-Control Studies; Female; Humans; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Losartan; Male; Middle Aged; Neutrophils

2011
Iterative CT reconstruction of aortic intramural hematoma.
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:7

    Topics: Amlodipine; Aortic Aneurysm; Aortic Dissection; Captopril; Drug Therapy, Combination; Female; Hematoma; Humans; Hydralazine; Metoprolol; Middle Aged; Multidetector Computed Tomography; Simvastatin; Treatment Outcome

2011
The difficulty of medical management of Cushing disease.
    Acta medica Indonesiana, 2011, Volume: 43, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Captopril; Clonidine; Female; Humans; Mineralocorticoid Receptor Antagonists; Pituitary ACTH Hypersecretion; Potassium; Spironolactone; Young Adult

2011
Effects of antihypertensive and triglyceride lowering agents on splenocyte apoptosis in rats with fatty liver.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 113, Issue:1

    Topics: Amlodipine; Animals; Antihypertensive Agents; Apoptosis; Bezafibrate; Blood Pressure; Captopril; Caspase 3; Fatty Liver; Hypolipidemic Agents; Lipids; Male; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Spleen; Triglycerides

2013
Liquid chromatographic method for the simultaneous determination of captopril, piroxicam, and amlodipine in bulk drug, pharmaceutical formulation, and human serum by programming the detector.
    Journal of separation science, 2013, Volume: 36, Issue:19

    Topics: Amlodipine; Captopril; Chemistry, Pharmaceutical; Chromatography, Liquid; Healthy Volunteers; Humans; Molecular Structure; Pharmaceutical Preparations; Piroxicam; Spectrophotometry, Ultraviolet

2013
Influence of antihypertensive drugs on aortic and coronary effects of Ang-(1-7) in pressure-overloaded rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, Mar-23, Volume: 50, Issue:4

    Topics: Amlodipine; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Calcium Channel Blockers; Captopril; Coronary Vessels; Losartan; Male; Mineralocorticoid Receptor Antagonists; Models, Animal; Peptide Fragments; Rats, Wistar; Reproducibility of Results; Spironolactone; Time Factors; Vasoconstriction; Vasodilation

2017
A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:9

    Topics: Amlodipine; Benzazepines; Captopril; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Taste; Taste Perception; Telmisartan; Valsartan

2019