Compounds > amlodipine

amlodipine and candesartan

amlodipine has been researched along with candesartan in 87 studies

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's33 (37.93)29.6817
2010's45 (51.72)24.3611
2020's9 (10.34)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Iwao, H; Izumi, Y; Kim, S; Zhan, Y1
Garcha, RS; Hughes, AD; Sever, PS1
Higaki, J; Iegushi, K; Maekawa, Y; Moriguchi, A; Ogihara, T; Ohishi, M; Orita, H; Rakugi, H; Sugimoto, K1
Hayashi, H; Horiguchi, M; Hosoya, T; Ishikawa, M; Kobayashi, H; Kuriyama, S; Tokudome, G; Tomonari, H1
Barenbrock, M; Hausberg, M; Kisters, K; Kosch, M; Tokmak, F1
Inomata, K; Tanaka, H1
Mandal, AK1
Lindholm, LH1
Ishii, K; Jin, D; Kirimura, K; Miyazaki, M; Muramatsu, M; Sakaguchi, M; Sakonjo, H; Takai, S1
Strauss, M; Verma, S1
Higaki, Y; Higashihara, E; Horie, S; Hosoya, T; Kamura, K; Mochizuki, T; Nakayama, T; Nutahara, K; Shimizu, T; Tsuchiya, K; Yamamoto, N1
Fischer, K; Kairane, C; Kampus, P; Muda, P; Ristimäe, T; Teesalu, R; Zilmer, K; Zilmer, M1
Ioroi, T; Iwao, H; Izumi, Y; Izumiya, Y; Kim-Mitsuyama, S; Tanaka, T; Wanibuchi, H; Yamamoto, E; Zhan, Y1
Bilous, R; Karalliedde, J; Krimholtz, MJ; Thomas, S; Viberti, G1
Honda, T; Inada, H; Ishimitsu, T; Kobayashi, T; Matsuoka, H; Minami, J; Ohta, S; Ono, H; Takahashi, M; Yoshii, M1
Safar, ME1
Asmar, R; Calvo, C; London, G; Schmieder, R1
Haneda, M; Iwashima, Y; Okada, M; Yoshida, T1
Aizawa, Y; Atarashi, H; Fukatani, M; Hirai, M; Hirayama, A; Inoue, H; Kamakura, S; Kato, T; Kodama, I; Koretsune, Y; Kumagai, K; Kurachi, Y; Mitamura, H; Nakaya, H; Ogawa, S; Ohe, T; Ohtsu, H; Okumura, K; Saikawa, T; Sakurai, M; Sugi, K; Watanabe, E; Yamashita, T; Yamazaki, T1
Doran, DE; Griendling, KK; Taylor, WR; Weiss, D; Zhang, Y1
Koji, Y; Motobe, K; Shiina, K; Tomiyama, H; Yamada, J; Yamashina, A; Yambe, M; Yoshida, M1
Fischer, K; Kampus, P; Muda, P; Ristimäe, T; Teesalu, R; Zilmer, K; Zilmer, M1
Abe, C; Akashiba, A; Ishimitsu, T; Kameda, T; Matsuoka, H; Minami, J; Takahashi, T1
Fujita, T; Gohchi, K; Shimosawa, T; Yatomi, Y1
Jaimes, EA; Pearse, DD; Puzis, L; Raij, L; Zhou, MS1
Fukiyama, K; Fukui, T; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Sato, T; Ueshima, K1
Azuma, J; Fujimoto, A; Fukiyama, K; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Sato, T; Ueshima, K; Yasuno, S1
Fujimoto, A; Nakao, K; Ogihara, T; Saruta, T2
Fujimoto, A; Fukiyama, K; Fukui, T; Matsuoka, H; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Shimamoto, K; Ueshima, K1
Han, SH; Kim, SJ; Koh, KK; Koh, Y; Lee, Y; Quon, MJ; Shin, EK1
Fujimoto, A; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Ueshima, K; Yasuno, S1
Fukiyama, K; Fukui, T; Hayashi, K; Nakao, K; Ogihara, T; Saruta, T1
Cao, T; Chen, X; Feng, X; He, H; Liu, D; Luo, Z; Ma, L; Ma, S; Tepel, M; Yan, Z; Yang, D; Zhu, Z1
Akie, Y; Aritomi, S; Nakamura, Y; Nakayama, A; Satoh, Y; Sugiyama, A; Takahara, A; Wagatsuma, H1
Ando, C; Inoue, Y; Kodama, S; Mihara, H; Miyoshi, K; Niimura, H; Okamura, K; Sumi, S; Tojyo, H; Tsuchiya, Y; Urata, H; Yamanouchi, Y1
Fujimoto, A; Hirata, M; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Ueshima, K; Yasuno, S1
Cohen, CD; Gaspert, A; Schorn, R1
Hagiwara, N; Kasanuki, H; Koyanagi, R; Mori, F; Nagashima, M; Ogawa, H; Takagi, A; Yagi, M; Yamaguchi, J1
Jin, D; Miyazaki, M; Sakonjo, H; Shimosato, T; Takai, S1
Benduhn, H; Klebs, S; Schweizer, J; Ulmer, HJ1
Aizawa, Y; Atarashi, H; Fukatani, M; Hirai, M; Hirayama, A; Inoue, H; Kamakura, S; Kato, T; Kodama, I; Koretsune, Y; Kumagai, K; Kurachi, Y; Mitamura, H; Nakaya, H; Ogawa, S; Ohe, T; Ohtsu, H; Okumura, K; Saikawa, T; Sakurai, M; Sato, T; Sugi, K; Watanabe, E; Yamashita, T; Yamazaki, T1
Fujimoto, A; Nakao, K; Ogihara, T; Saruta, T; Ueshima, K1
Fujiwara, H; Matsuno, Y; Minatoguchi, S1
Goette, A1
Dohi, Y; Ichikawa, T; Ito, M; Kato, T; Kimura, G; Kojima, M; Komada, T; Machida, H; Miyazaki, T; Nakatani, K; Ninomiya, T; Okura, T; Sugiyama, M; Watanabe, Y1
Bekki, H; Fukami, K; Homma, T; Nakata, M; Nohara, M; Okuda, S; Sone, M; Yamagishi, S; Yamamoto, K1
Matsumoto, C; Odaira, M; Shiina, K; Tomiyama, H; Yamada, J; Yamashina, A; Yoshida, M1
Ueshima, K1
Agnoletti, D; Blacher, J; Safar, ME; Zhang, Y1
Fujimoto, A; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Tanaka, S; Ueshima, K; Yasuno, S1
Fujimoto, A; Fukiyama, K; Matsuoka, H; Nakao, K; Oba, K; Ogihara, T; Saruta, T; Sato, T; Ueshima, K; Yasuno, S1
Dong, YF; Kataoka, K; Kim-Mitsuyama, S; Koibuchi, N; Nakamura, T; Ogawa, H; Sueta, D; Toyama, K; Yamamoto, E; Yasuda, O1
Fujimoto, A; Ueshima, K; Yasuno, S1
Azushima, K; Dejima, T; Fujikawa, T; Haku, S; Kanaoka, T; Maeda, A; Mizushima, S; Ohsawa, M; Okano, Y; Tamura, K; Tochikubo, O; Toya, Y; Umemura, S; Wakui, H; Yanagi, M1
Daikuhara, H; Ishida, T; Kikuchi, F1
Dohi, K; Hiraoka, N; Hoshino, K; Ito, M; Kitai, T; Kumagai, N; Nakamori, S; Nakamura, M; Okamoto, S; Onishi, K; Oota, M; Ueda, Y; Yamada, T; Yazu, T1
Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T1
Agnoletti, D; Blacher, J; Borghi, C; Safar, ME; Zhang, Y1
Hagiwara, N; Haruta, S; Kawada-Watanabe, E; Koyanagi, R; Ogawa, H; Takagi, A; Yamaguchi, J1
Bramlage, P; Fimmers, R; Gansz, A; Lüders, S; Nadal, J; Schmieder, RE; Schrader, J; Sturm, CD; Zemmrich, C2
Bianchetti, MG; Ferrarini, A; Lava, SA; Mardegan, C; Milani, GP; Santi, M; Simonetti, GD; Uestuener, P1
Izumikawa, Y; Kato, H; Kojima, K; Kubo, E; Nagura, M; Nosaka, H; Shima, T; Shimada, M; Shiraishi, T; Tanemoto, M; Tomioka, S; Uchida, S; Ueda, S; Yano, H1
Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Donner, KM; Frau, F; Glorioso, N; Glorioso, V; Gong, Y; Gums, JG; Hiltunen, TP; Johnson, JA; Kontula, KK; Ripatti, S; Saarela, J; Salvi, E; Sarin, AP; Turner, ST; Zaninello, R1
Arora, A; Jain, S; Khuller, GK; Malhotra, S; Shafiq, N; Sharma, S1
Piecha, G; Skoczylas, A; Więcek, A1
Špinar, J; Vítovec, J1
Hoshide, S; Kario, K; Mizuno, H; Tomitani, N1
DeObeso-Gonzalez, E; Flores-Villalba, E; Lammel-Lindemann, JA; Martagón, AJ; Puente-Gallegos, F1
Higa, A; Hoshi, H; Imai, JI; Ito, E; Morisawa, G; Takagi, M; Watanabe, S; Yanagisawa, Y1
Cheng, YQ; Dong, WZ; Liu, AJ; Su, DF; Tan, BY; Yu, XH; Zhu, DQ1
Bramlage, P; Schmidt, S; Sims, H1
Ichihara, C; Kitao, H; Konda, M; Kuwabara, Y; Liu, J; Oba, K; Ueshima, K; Yasuno, S1
Huh, W; Kim, JR; Kim, S; Ko, JW1
Ekman, I; Lind, L; Lytsy, P; Marttala, K; Nowrouzi, S; Öhagen, P; Östlund, O; Sundström, J1
Bachmann, HS; Besser, M; Severing, AL; Stuermer, EK; Terberger, N1
Bhandari, RK; Bhatia, A; Kaur, N; Malhotra, S; Pandey, AK; Rather, IIG; Shafiq, N; Sharma, S1
Gundlach, K; Randerath, O; Salem, I; Seiler, D; Wolf, K1
Lauder, L; Mahfoud, F; Meyer, MR; Vollmer, AC; Wagmann, L1
Abdelazim, AH; Ramzy, S; Shahin, M1
Cheng, YQ; Guo, PY; Liu, AJ; Shi, WT; Xia, T; Xu, LL1
Hagström, E; Held, C; Lind, L; Lytsy, P; Marttala, K; Neal, B; Nowrouzi, S; Östlund, O; Sundström, J1
Abe, M; Fukuda, N; Hara, T; Ishizuka, M; Ito, H; Katakawa, M; Otsuka, N1
Hirata, T; Ishii, T; Kokuba, S; Nakamura, K; Shiohira, H; Tayag, JCS1
Tchernev, G1

Reviews

3 review(s) available for amlodipine and candesartan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[What are the effects of fixed-dose combination of candesartan and amlodipine].
    Vnitrni lekarstvi, 2016, Volume: 62, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Combinations; Humans; Hypertension; Tetrazoles

2016
Noncholestatic acute hepatocellular injury following candesartan administration.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:1

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Humans; Hypertension; Liver Function Tests; Male; Tetrazoles

2018

Trials

42 trial(s) available for amlodipine and candesartan

ArticleYear
Antiproteinuric effects of combined antihypertensive therapies in patients with overt type 2 diabetic nephropathy.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:6

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Pilot Projects; Proteinuria; Tetrazoles; Thiazepines; Treatment Outcome

2002
Calcium channel blocker versus angiotensin II receptor blocker in autosomal dominant polycystic kidney disease.
    Nephron. Clinical practice, 2005, Volume: 99, Issue:1

    Topics: Adult; Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Creatinine; Female; Humans; Male; Middle Aged; Polycystic Kidney, Autosomal Dominant; Prospective Studies; Proteinuria; Tetrazoles

2005
Effect of antihypertensive treatment with candesartan or amlodipine on glutathione and its redox status, homocysteine and vitamin concentrations in patients with essential hypertension.
    Journal of hypertension, 2005, Volume: 23, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Folic Acid; Glutathione; Glutathione Disulfide; Homocysteine; Humans; Hypertension; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Tetrazoles; Vitamin B 12

2005
Targeting albumin excretion rate in the treatment of the hypertensive diabetic patient with renal disease.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16 Suppl 1

    Topics: Adult; Aged; Albuminuria; Amlodipine; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Kidney Function Tests; Male; Maximum Tolerated Dose; Middle Aged; Probability; Reference Values; Risk Assessment; Severity of Illness Index; Tetrazoles; Treatment Outcome

2005
Protective effects of an angiotensin II receptor blocker and a long-acting calcium channel blocker against cardiovascular organ injuries in hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:4

    Topics: Adult; Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Creatinine; Female; Heart Rate; Humans; Hypertension, Renal; Hypertrophy, Left Ventricular; Male; Middle Aged; Peptide Fragments; Procollagen; Tetrazoles

2005
Indapamide SR versus candesartan and amlodipine in hypertension: the X-CELLENT Study.
    American journal of hypertension, 2006, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Diastole; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Indapamide; Male; Middle Aged; Prognosis; Sodium; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles

2006
Regression of cardiac hypertrophy in type 2 diabetes with hypertension by candesartan.
    Diabetes research and clinical practice, 2006, Volume: 74, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Patient Selection; Tetrazoles; Ventricular Dysfunction, Left

2006
Randomized study of angiotensin II type 1 receptor blocker vs dihydropiridine calcium antagonist for the treatment of paroxysmal atrial fibrillation in patients with hypertension.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:10

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Dihydropyridines; Humans; Hypertension; Secondary Prevention; Tetrazoles

2006
Discrepancy between improvement of insulin sensitivity and that of arterial endothelial function in patients receiving antihypertensive medication.
    Journal of hypertension, 2007, Volume: 25, Issue:4

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; C-Reactive Protein; Calcium Channel Blockers; Carotid Artery, Common; Endothelium, Vascular; Female; Forearm; Heart Ventricles; Humans; Hypertension; Insulin Resistance; Linear Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Regional Blood Flow; Research Design; Tetrazoles; Treatment Outcome; Tunica Intima; Tunica Media; Vascular Resistance

2007
Effects of amlodipine and candesartan on oxidized LDL level in patients with mild to moderate essential hypertension.
    Blood pressure, 2006, Volume: 15, Issue:5

    Topics: Alkenes; Amlodipine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Lipids; Lipoproteins, LDL; Male; Middle Aged; Tetrazoles

2006
Long-term efficacy of combination therapy with losartan and low-dose hydrochlorothiazide in patients with uncontrolled hypertension.
    International heart journal, 2007, Volume: 48, Issue:2

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Treatment Outcome

2007
Effectiveness of add-on low-dose diuretics in combination therapy for hypertension: losartan/hydrochlorothiazide vs. candesartan/amlodipine.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Benzimidazoles; Biphenyl Compounds; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome

2007
Effects of candesartan compared with amlodipine in hypertensive patients with high cardiovascular risks: candesartan antihypertensive survival evaluation in Japan trial.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:2

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Hypertension; Incidence; Male; Middle Aged; Risk; Risk Factors; Tetrazoles; Treatment Outcome

2008
ARB candesartan and CCB amlodipine in hypertensive patients: the CASE-J trial.
    Expert review of cardiovascular therapy, 2008, Volume: 6, Issue:9

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Hypertension; Hypertrophy, Left Ventricular; Incidence; Japan; Male; Middle Aged; Prospective Studies; Risk Factors; Tetrazoles

2008
Distinct vascular and metabolic effects of different classes of anti-hypertensive drugs.
    International journal of cardiology, 2010, Apr-01, Volume: 140, Issue:1

    Topics: Adipokines; Adiponectin; Adult; Aged; Amlodipine; Antihypertensive Agents; Atenolol; Benzimidazoles; Biphenyl Compounds; Cholesterol, HDL; Comorbidity; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Single-Blind Method; Tetrazoles; Triglycerides

2010
Effects of candesartan and amlodipine on cardiovascular events in hypertensive patients with chronic kidney disease: subanalysis of the CASE-J Study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:6

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Chronic Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypertension; Japan; Kaplan-Meier Estimate; Kidney Diseases; Male; Middle Aged; Risk Factors; Survival Analysis; Tetrazoles

2009
Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment.
    International heart journal, 2009, Volume: 50, Issue:5

    Topics: Aged; Amlodipine; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Nifedipine; Tetrazoles

2009
Effect of amlodipine + candesartan on cardiovascular events in hypertensive patients with coronary artery disease (from The Heart Institute of Japan Candesartan Randomized Trial for Evaluation in Coronary Artery Disease [HIJ-CREATE] Study).
    The American journal of cardiology, 2010, Sep-15, Volume: 106, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angina, Unstable; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Japan; Male; Middle Aged; Risk Factors; Tetrazoles; Treatment Outcome

2010
Efficacy and tolerability of aliskiren 300  mg/hydrochlorothiazide 25  mg (± amlodipine 5  mg) in hypertensive patients not controlled by candesartan 32  mg plus HCT 25  mg.
    Current medical research and opinion, 2011, Volume: 27, Issue:1

    Topics: Adult; Aged; Algorithms; Amides; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Failure; Treatment Outcome

2011
Randomized trial of angiotensin II-receptor blocker vs. dihydropiridine calcium channel blocker in the treatment of paroxysmal atrial fibrillation with hypertension (J-RHYTHM II study).
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2011, Volume: 13, Issue:4

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Comorbidity; Female; Follow-Up Studies; Humans; Hypertension; Japan; Male; Middle Aged; Prevalence; Quality of Life; Tetrazoles; Time Factors; Treatment Outcome

2011
Effects of candesartan versus amlodipine on home-measured blood pressure, QT dispersion and left ventricular hypertrophy in high-risk hypertensive patients.
    Blood pressure. Supplement, 2011, Volume: 1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Electrocardiography; Female; Follow-Up Studies; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Risk; Tetrazoles; Treatment Outcome; Ultrasonography

2011
Effects of up-titration of candesartan versus candesartan plus amlodipine on kidney function in type 2 diabetic patients with albuminuria.
    Journal of human hypertension, 2012, Volume: 26, Issue:4

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Comorbidity; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome

2012
Beneficial cardiometabolic actions of telmisartan plus amlodipine therapy in elderly patients with poorly controlled hypertension.
    Clinical cardiology, 2011, Volume: 34, Issue:4

    Topics: Adiponectin; Age Factors; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Drug Substitution; Drug Therapy, Combination; Female; Humans; Hypertension; Japan; Male; Prospective Studies; Telmisartan; Tetrazoles; Time Factors; Treatment Outcome; Up-Regulation; Valine; Valsartan

2011
Arterial-cardiac destiffening following long-term antihypertensive treatment.
    American journal of hypertension, 2011, Volume: 24, Issue:10

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Ankle Brachial Index; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Diastole; Female; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Tetrazoles; Vascular Stiffness

2011
[Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2011, May-10, Volume: 100, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Tetrazoles

2011
Effect of antihypertensive agents on blood pressure variability: the Natrilix SR versus candesartan and amlodipine in the reduction of systolic blood pressure in hypertensive patients (X-CELLENT) study.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Delayed-Action Preparations; Female; Heart Rate; Humans; Hypertension; Indapamide; Male; Middle Aged; Tetrazoles; Treatment Outcome

2011
Long-term effects of candesartan and amlodipine on cardiovascular morbidity and mortality in Japanese high-risk hypertensive patients: the Candesartan Antihypertensive Survival Evaluation in Japan Extension Study (CASE-J Ex).
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:12

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Utilization; Endpoint Determination; Female; Humans; Hypertension; Japan; Long-Term Care; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Risk; Survival Analysis; Tetrazoles; Time; Treatment Outcome

2011
[Clinical implications from the results of the CASE-J extension].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70, Issue:3

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles

2012
Combination therapy of angiotensin II receptor blocker and calcium channel blocker exerts pleiotropic therapeutic effects in addition to blood pressure lowering: amlodipine and candesartan trial in Yokohama (ACTY).
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:4

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Creatinine; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hypertension; Insulin Resistance; Japan; Male; Middle Aged; Tetrazoles

2012
The combination of OLmesartan and a CAlcium channel blocker (azelnidipine) or candesartan and a calcium channel blocker (amlodipine) in type 2 diabetic hypertensive patients: the OLCA study.
    Diabetes & vascular disease research, 2012, Volume: 9, Issue:4

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Therapy, Combination; Female; Glycated Hemoglobin; Heart Rate; Humans; Hypertension; Imidazoles; Japan; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome

2012
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
    Blood pressure, 2013, Volume: 22 Suppl 1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan

2013
Effects of antihypertensive drugs on central blood pressure in humans: a preliminary observation.
    American journal of hypertension, 2013, Volume: 26, Issue:8

    Topics: Aged; Amlodipine; Antihypertensive Agents; Aorta; Arterial Pressure; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Brachial Artery; Double-Blind Method; Female; Humans; Hypertension; Indapamide; Male; Manometry; Middle Aged; Pulse Wave Analysis; Tetrazoles; Treatment Outcome; Vascular Stiffness

2013
Efficacy of the combination of amlodipine and candesartan in hypertensive patients with coronary artery disease: a subanalysis of the HIJ-CREATE study.
    Journal of cardiology, 2013, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Forecasting; Humans; Hypertension; Incidence; Male; Middle Aged; Prospective Studies; Risk; Tetrazoles

2013
Daytime systolic ambulatory blood pressure with a direct switch between candesartan monotherapy and the fixed-dose combination olmesartan/amlodipine in patients with uncontrolled essential hypertension (SEVICONTROL-1).
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:11

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Systole; Tetrazoles; Treatment Outcome

2013
Daytime systolic ambulatory blood pressure with a two-step switch from candesartan to olmesartan monotherapy and the fixed-dose combination of olmesartan/amlodipine in patients with uncontrolled essential hypertension (SEVICONTROL-2).
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; White People

2014
Taste acceptability of pulverized brand-name and generic drugs containing amlodipine or candesartan.
    International journal of pharmaceutics, 2014, Jul-01, Volume: 468, Issue:1-2

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Chemistry, Pharmaceutical; Drugs, Generic; Female; Humans; Male; Middle Aged; Patient Satisfaction; Single-Blind Method; Taste Perception; Tetrazoles

2014
Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.
    Journal of the American Heart Association, 2015, Jan-26, Volume: 4, Issue:1

    Topics: Adult; Aldehyde Oxidoreductases; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Blood Pressure Monitoring, Ambulatory; Chloride Channels; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Essential Hypertension; Finland; Genome-Wide Association Study; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Membrane Proteins; Meta-Analysis as Topic; Microfilament Proteins; Middle Aged; Mutation, Missense; Pharmacogenetics; Polymorphism, Single Nucleotide; Severity of Illness Index; Tetrazoles; Treatment Outcome

2015
Comparison of ambulatory blood pressure-lowering effects of higher doses of different calcium antagonists in uncontrolled hypertension: the Calcium Antagonist Controlled-Release High-Dose Therapy in Uncontrolled Refractory Hypertensive Patients (CARILLON)
    Blood pressure, 2017, Volume: 26, Issue:5

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium; Calcium Channel Blockers; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Tetrazoles

2017
No pharmacokinetic interactions between candesartan and amlodipine following multiple oral administrations in healthy subjects.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Administration, Oral; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Healthy Volunteers; Humans; Male; Middle Aged; Republic of Korea; Tetrazoles; Young Adult

2018
The Precision HYpertenSIon Care (PHYSIC) study: a double-blind, randomized, repeated cross-over study.
    Upsala journal of medical sciences, 2019, Volume: 124, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Precision Medicine; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Tetrazoles

2019
Safety of Candesartan, Amlodipine, and Atorvastatin in Combination: Interaction Study in Healthy Subjects.
    Clinical pharmacology in drug development, 2021, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Amlodipine; Antihypertensive Agents; Area Under Curve; Atorvastatin; Benzimidazoles; Biphenyl Compounds; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Prospective Studies; Tetrazoles; Young Adult

2021
Heterogeneity in Blood Pressure Response to 4 Antihypertensive Drugs: A Randomized Clinical Trial.
    JAMA, 2023, 04-11, Volume: 329, Issue:14

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Precision Medicine

2023

Other Studies

42 other study(ies) available for amlodipine and candesartan

ArticleYear
Cardiovascular effects of combination of perindopril, candesartan, and amlodipine in hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:3

    Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Antihypertensive Agents; Aorta; Atrial Natriuretic Factor; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bradykinin; Calcium; Calcium Channel Blockers; Drug Therapy, Combination; ErbB Receptors; Gene Expression; Heart Ventricles; Hypertension; Myocardium; Organ Size; Perindopril; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Stroke; Tetrazoles

2000
Mechanism of action of angiotensin II in human isolated subcutaneous resistance arteries.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: Amlodipine; Angiotensin II; Arteries; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Flavonoids; Genistein; Humans; In Vitro Techniques; Nickel; Norepinephrine; Potassium; Ryanodine; Skin; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

2001
[A case of severe systemic edema in an elderly hypertensive patient with systemic lupus erythematodes during long-term treatment with anti-hypertensive drugs].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001, Volume: 38, Issue:5

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Edema; Female; Humans; Lupus Erythematosus, Systemic; Tetrazoles

2001
Effects of candesartan and amlodipine on renal function and electrolytes in renal allograft recipients.
    Clinical nephrology, 2002, Volume: 58, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Kidney; Kidney Transplantation; Tetrazoles

2002
Protective effect of benidipine against sodium azide-induced cell death in cultured neonatal rat cardiac myocytes.
    Journal of pharmacological sciences, 2003, Volume: 93, Issue:2

    Topics: Adenosine Triphosphate; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Cell Death; Cells, Cultured; Cysteine Proteinase Inhibitors; Dihydropyridines; Dipeptides; Dose-Response Relationship, Drug; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria, Muscle; Myocytes, Cardiac; Nifedipine; Rats; Rats, Sprague-Dawley; Sodium Azide; Tetrazoles

2003
Reply to Kisters. "Effects of candesartan and amlodipine on renal function and electrolytes in renal allograft recipients".
    Clinical nephrology, 2003, Volume: 60, Issue:5

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Humans; Kidney; Kidney Transplantation; Tetrazoles; Water-Electrolyte Balance

2003
Valsartan treatment of hypertension--does VALUE add value?
    Lancet (London, England), 2004, Jun-19, Volume: 363, Issue:9426

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Endpoint Determination; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan

2004
Comparative effects of candesartan and amlodipine in a monkey atherosclerotic model.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:7

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Aortic Diseases; Arteriosclerosis; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cholesterol; Cholesterol, Dietary; Female; Macaca fascicularis; Male; Peptidyl-Dipeptidase A; Renin; Tetrazoles

2004
Angiotensin receptor blockers and myocardial infarction.
    BMJ (Clinical research ed.), 2004, Nov-27, Volume: 329, Issue:7477

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Myocardial Infarction; Tetrazoles; Truth Disclosure; Valine; Valsartan

2004
Critical role of angiotensin II in excess salt-induced brain oxidative stress of stroke-prone spontaneously hypertensive rats.
    Stroke, 2005, Volume: 36, Issue:5

    Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood-Brain Barrier; Calcium Channel Blockers; Cell Proliferation; Cerebral Arteries; Cerebral Cortex; Disease Models, Animal; Hippocampus; Hypertensive Encephalopathy; Male; Neurons; Oxidative Stress; Rats; Rats, Inbred SHR; Sodium Chloride; Stroke; Superoxides; Tetrazoles

2005
The X-cellent Study.
    American journal of hypertension, 2006, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Randomized Controlled Trials as Topic; Sodium; Sodium Chloride Symporter Inhibitors; Tetrazoles

2006
Differential effects of AT1 receptor and Ca2+ channel blockade on atherosclerosis, inflammatory gene expression, and production of reactive oxygen species.
    Atherosclerosis, 2007, Volume: 195, Issue:1

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Animals; Aorta; Atherosclerosis; Benzimidazoles; Biphenyl Compounds; Calcium Channels; Disease Models, Animal; Gene Expression Regulation; Hydrogen Peroxide; Inflammation; Mice; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Tetrazoles

2007
Upregulation of cortical COX-2 in salt-sensitive hypertension: role of angiotensin II and reactive oxygen species.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:2

    Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Gene Expression; Hypertension; Kidney Cortex; Kidney Medulla; Male; Membrane Proteins; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Sodium Chloride, Dietary; Spin Labels; Tetrazoles; Up-Regulation

2008
Long-term effects of candesartan and amlodipine on cardiovascular mortality and morbidity in Japanese high-risk hypertensive patients: rationale, design, and characteristics of candesartan antihypertensive survival evaluation in Japan extension (CASE-J Ex
    Contemporary clinical trials, 2009, Volume: 30, Issue:1

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Female; Humans; Hypertension; Japan; Male; Middle Aged; Tetrazoles

2009
The optimal target blood pressure for antihypertensive treatment in Japanese elderly patients with high-risk hypertension: a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:8

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Asian People; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Death, Sudden, Cardiac; Female; Humans; Hypertension; Incidence; Japan; Male; Morbidity; Proportional Hazards Models; Risk Factors; Tetrazoles

2008
Effects of cardiac complications on cardiovascular events in Japanese high-risk hypertensive patients: subanalysis of the CASE-J trial.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:6

    Topics: Adrenergic Antagonists; Aged; Amlodipine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Follow-Up Studies; Humans; Hypertension; Hypertrophy, Left Ventricular; Incidence; Japan; Middle Aged; Myocardial Ischemia; Prognosis; Risk Factors; Tetrazoles

2009
Increased rhythmicity in hypertensive arterial smooth muscle is linked to transient receptor potential canonical channels.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:10

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Boron Compounds; Calcium; Calcium Channels; Hypertension; Imidazoles; In Vitro Techniques; Muscle, Smooth, Vascular; Norepinephrine; Periodicity; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Telmisartan; Tetrazoles; TRPC Cation Channels; Verapamil

2010
Long-term blockade of L/N-type Ca(2+) channels by cilnidipine ameliorates repolarization abnormality of the canine hypertrophied heart.
    British journal of pharmacology, 2009, Volume: 158, Issue:5

    Topics: Action Potentials; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrioventricular Block; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cardiomegaly; Chronic Disease; Dihydropyridines; Dogs; Electrocardiography; Epinephrine; Female; Male; Neurotransmitter Agents; Norepinephrine; Tetrazoles; Time Factors

2009
Effects of antihypertensive drugs in the prevention of new-onset diabetes mellitus in patients with hypertension at high-risk of cardiovascular events in relation to aging.
    Journal of the American Geriatrics Society, 2010, Volume: 58, Issue:2

    Topics: Age Distribution; Age Factors; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 2; Disease Susceptibility; Female; Follow-Up Studies; Humans; Hypertension; Incidence; Japan; Male; Middle Aged; Tetrazoles

2010
Role of diabetes and obesity in outcomes of the candesartan antihypertensive survival evaluation in Japan (CASE-J) trial.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:6

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Mass Index; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Incidence; Japan; Male; Middle Aged; Obesity; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome

2010
[Anti-RNA polymerase III antibodies in scleroderma renal crisis].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:22

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Antinuclear; Benzimidazoles; Biopsy; Biphenyl Compounds; Combined Modality Therapy; Diagnosis, Differential; Humans; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Lisinopril; Male; Plasmapheresis; Renal Dialysis; RNA Polymerase II; Scleroderma, Systemic; Tetrazoles; Thrombotic Microangiopathies; Vasodilator Agents

2010
Candesartan and amlodipine combination therapy provides powerful vascular protection in stroke-prone spontaneously hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:2

    Topics: Acetylcholine; Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Vessels; Diuretics; Drug Therapy, Combination; Gene Expression Regulation; Hydrochlorothiazide; Male; Malondialdehyde; NADPH Oxidases; Rats; Rats, Inbred SHR; Rats, Wistar; Stroke; Superoxide Dismutase; Tetrazoles; Vasodilation; Vasodilator Agents

2011
Age-related differences in the effects of antihypertensive therapy on left ventricular hypertrophy in high-risk patients with hypertension-candesartan antihypertensive survival evaluation in Japan subanalysis.
    Journal of the American Geriatrics Society, 2011, Volume: 59, Issue:1

    Topics: Age Factors; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Comorbidity; Humans; Hypertension; Hypertrophy, Left Ventricular; Japan; Middle Aged; Tetrazoles; Treatment Outcome

2011
The vanishing story of angiotensin II receptor blockers in the treatment of atrial fibrillation.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2011, Volume: 13, Issue:4

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Comorbidity; Humans; Hypertension; Prevalence; Tetrazoles; Treatment Outcome

2011
Influence of coronary risk factors on coronary events in Japanese high-risk hypertensive patients. - Primary and secondary prevention of ischemic heart disease in a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) tria
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:10

    Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Benzimidazoles; Biphenyl Compounds; Coronary Artery Disease; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia; Observation; Risk Factors; Secondary Prevention; Tetrazoles

2011
Amlodipine enhances amelioration of vascular insulin resistance, oxidative stress, and metabolic disorders by candesartan in metabolic syndrome rats.
    American journal of hypertension, 2012, Volume: 25, Issue:6

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Calcium Channel Blockers; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Heart Rate; Insulin Resistance; Male; Metabolic Syndrome; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred WKY; Superoxides; Tetrazoles; Vasodilation

2012
Improving drug adherence using fixed combinations caused beneficial treatment outcomes and decreased health-care costs in patients with hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:5

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Health Care Costs; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Prospective Studies; Retrospective Studies; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2013
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology.
    Clinical and experimental nephrology, 2015, Volume: 19, Issue:3

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Drug Costs; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Nephrology; Patient Satisfaction; Practice Patterns, Physicians'; Renal Insufficiency, Chronic; Retrospective Studies; Surveys and Questionnaires; Telmisartan; Tetrazoles; Valsartan

2015
Development of Sustained Release "NanoFDC (Fixed Dose Combination)" for Hypertension - An Experimental Study.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Carriers; Drug Liberation; Half-Life; Hydrochlorothiazide; Hypertension; Lactic Acid; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Tetrazoles

2015
Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations.
    Polskie Archiwum Medycyny Wewnetrznej, 2016, Apr-29, Volume: 126, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Apelin; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Calcium Channel Blockers; Cytokines; Diuretics; Essential Hypertension; Female; Humans; Hypertension; Indapamide; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Nicotinamide Phosphoribosyltransferase; Obesity; Random Allocation; Resistin; Tetrazoles; Treatment Outcome

2016
Evaluation system for arrhythmogenic potential of drugs using human-induced pluripotent stem cell-derived cardiomyocytes and gene expression analysis.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:6

    Topics: Amlodipine; Arrhythmias, Cardiac; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Cardiotoxicity; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Profiling; Gene Expression Regulation; Humans; Induced Pluripotent Stem Cells; Linagliptin; Long QT Syndrome; Myocytes, Cardiac; Naphthalenes; Phenylpropionates; Piperazines; Prasugrel Hydrochloride; Pyridazines; Sumatriptan; Tetrazoles; Transcriptome; Up-Regulation

2017
Synergism of amlodipine and candesartan on blood pressure reduction and organ protection in hypertensive rats.
    Clinical and experimental pharmacology & physiology, 2018, Volume: 45, Issue:6

    Topics: Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; Male; Rats; Rats, Sprague-Dawley; Tetrazoles; Time Factors

2018
Fixed-dose vs free-dose combinations for the management of hypertension-An analysis of 81 958 patients.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Comorbidity; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Ramipril; Tetrazoles

2018
Long-term effects of antihypertensive therapy on cardiovascular events and new-onset diabetes mellitus in high-risk hypertensive patients in Japan.
    Journal of hypertension, 2018, Volume: 36, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Hypertension; Incidence; Japan; Kidney Diseases; Male; Middle Aged; Retrospective Studies; Risk Factors; Tetrazoles; Time Factors

2018
Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitro.
    Skin pharmacology and physiology, 2019, Volume: 32, Issue:3

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cell Line; Cell Movement; Diuretics; Fibroblasts; Humans; Hydrochlorothiazide; Keratinocytes; Metoprolol; Ramipril; Tetrazoles; Wound Healing

2019
Pharmacokinetic and pharmacodynamic evaluation of nano-fixed dose combination for hypertension.
    Journal of hypertension, 2020, Volume: 38, Issue:8

    Topics: Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Drug Combinations; Hydrochlorothiazide; Hypertension; Male; Nanoparticles; Rats; Rats, Wistar; Tetrazoles

2020
Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry Analysis.
    Molecules (Basel, Switzerland), 2021, Mar-09, Volume: 26, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Fluids; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Hypertension; Imidazoles; Liquid-Liquid Extraction; Metoprolol; Patient Compliance; Pilot Projects; Plasma; Reference Values; Reproducibility of Results; Tandem Mass Spectrometry; Tetrazoles

2021
Quantitative Analysis of Two Pharmaceutical Combinations Containing Amlodipine with Either Bisoprolol or Candesartan Using Different UV Spectrophotometric Methods.
    Journal of AOAC International, 2022, Jun-29, Volume: 105, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Humans; Leukemia, Myeloid, Acute; Spectrophotometry; Tablets; Tetrazoles

2022
Synergism of amlodipine and telmisartan or candesartan on blood pressure reduction by using SynergyFinder 3.0 and probability sum test in vivo.
    Pharmacology research & perspectives, 2023, Volume: 11, Issue:2

    Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Hypotension; Rats; Rats, Inbred SHR; Telmisartan

2023
5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats.
    Journal of pharmacological sciences, 2023, Volume: 152, Issue:1

    Topics: Aminolevulinic Acid; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Bupivacaine; Hypertension; Hypotension; Hypotension, Controlled; Propofol; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2023
Effects of 5-fluorouracil Co-administration on Blood Pressure in Patients Maintained on Antihypertensives: a Retrospective Case Series.
    Die Pharmazie, 2023, 05-01, Volume: 78, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Fluorouracil; Humans; Hypertension; Nifedipine; Retrospective Studies; Tetrazoles; Valine; Valsartan

2023
THE NITROSAMINE CONTAMINATION IN BETA BLOCKERS (BISOPROLOL/METOPROLOL), ACE INHIBITORS (LISINOPRIL/PERINDOPRIL), THIAZIDES DIURETICS (HCT), CALCIUM CHANNEL BLOCKERS (AMLODIPINE/FELODIPINE), SARTANS (CANDESARTAN) AND ТHE SUBSEQUENT SKIN CANCER DEVELOPMENT
    Georgian medical news, 2023, Issue:337

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bisoprolol; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Felodipine; Humans; Lisinopril; Melanoma; Metoprolol; Nitrosamines; Perindopril; Prospective Studies; Skin Neoplasms; Sodium Chloride Symporter Inhibitors; Thiazides

2023