amlodipine and aliskiren

amlodipine has been researched along with aliskiren in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (10.00)	29.6817
2010's	53 (88.33)	24.3611
2020's	1 (1.67)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bizot, MN; Denouel, J; Dieterich, HA; Dole, WP; Kemp, C; Vaidyanathan, S; Valencia, J; Yeh, CM; Zhao, C	1
Boye, SW; Engeli, S; Jordan, J; Keefe, DL; Le Breton, S	1
Drummond, W; Keefe, DL; Khan, M; Maboudian, M; Munger, MA; Rafique Essop, M	1
Aubert, JF; Bouzourene, K; Hayoz, D; Mazzolai, L; Nussberger, J; Pellegrin, M	1
Hollanders, G; Liao, W; Littlejohn, TW; Trenkwalder, P; Zhao, Y	1
Benduhn, H; Klebs, S; Schweizer, J; Ulmer, HJ	1
Bakris, G; Lazich, I	1
Brown, MJ; MacDonald, TM; McInnes, GT; Papst, CC; Zhang, J	1
Izzo, JL; Zion, AS	2
Derosa, G; Fogari, R; Lazzari, P; Maffioli, P; Monti, C; Mugellini, A; Zoppi, A	2
Alriyami, M; Banerjee, Y; Taranikanti, V	1
Chan, SS; Rainer, TH	1
Remuzzi, G; Ruggenenti, P	1
Ferdinand, KC; Pool, J; Purkayastha, D; Townsend, R; Weitzman, R	1
Billecke, SS; Marcovitz, PA	1
Black, HR; Hilkert, R; Israel, M; Izzo, J; Lee, J; Purkayastha, D; Sridharan, K; Weinberger, MH	1
Baek, I; Drummond, W; Keefe, DL; Ramos, E; Sirenko, YM	1
Huang, J; Matavelli, LC; Siragy, HM	1
Chrysant, SG	1
Axthelm, C; Kaiser, E; Meister, F; Sieder, C	1
Bhosekar, V; Forker, AD; Keefe, DL; Townsend, RR; Yadao, A	1
Boschmann, M; Dahlke, M; Danser, AH; Engeli, S; Jordan, J; Nussberger, J; Prescott, MF; Yeh, CM	1
Argiolas, G; Baek, I; Glorioso, N; Patel, S; Thomas, M; Troffa, C; Zhang, J	1
Papst, CC; Pfeiffer, D; Rennie, N; Zhang, J	1
Jaimes, EA; Judd, E	1
Abe, M; Fujii, Y; Ito, M; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Yoshida, Y	1
Fang, H; Konis, G; Lacourcière, Y; Severin, T; Taddei, S; Zhang, J	1
Alvarez, C; Braun-Dullaeus, RC; Häring, DA; Hristoskova, S; Rogelio, GG; Shustov, SB; Zhang, J	1
Matavelli, LC; Siragy, HM	1
Huan, Y; Townsend, R	1
Hsu, H; Jones, SW; Keefe, DL; Littlejohn, TW; Zhang, J	1
Athyros, VG; Karagiannis, A; Katsiki, N; Mikhailidis, DP	1
Garcia-Puig, J; Koenig, W; Murray, AV; Patel, S; Uddin, A; Zhang, J	1
Abo-Salem, E; Doctolero, S; Irons, BK; Meyerrose, GE; Seifert, CF; Simoni, JS; Trujillo, A	1
Akyüz, A; Özdemir, FA	1
Chen, K; Han, Y; Kou, X; Liu, Y; Zeng, C; Zhou, L	1
Fukutomi, M; Hoshide, S; Kario, K; Mizuno, H	2
Hara, Y; Hosoya, T; Kuriyama, S; Sugano, N; Yokoo, T; Yokoyama, K	1
Cao, C; Dong, X; Gao, D; Liu, Y; Niu, X; Song, A; Wei, J; Yan, R	1
Agaliotis, GD; Andreadis, EA; Angelopoulos, ET; Kolyvas, GN; Mousoulis, CG; Mousoulis, GP	1
Belal, F; Ebeid, WM; El-Enany, N; Patonay, G; Salim, MM; Walash, M	1
Bosch, J; Copland, I; Dagenais, G; Dans, A; Diaz, R; Joseph, P; Jung, H; Liu, L; Mancia, G; O'Donnell, M; Pfeffer, M; Pogue, J; Teo, KK; Yusuf, S	1
Ebeid, WM; El-Bagary, RI; El-Zaher, AA; Elkady, EF; Patonay, G	2
Mannemala, SS; Nagarajan, JS	1
Ratzinger, M; Rosenkranz, AR	1
El-Zeany, BA; Elzanfaly, ES; Hassan, SA; Salem, MY	2
Ahmed, MS; El-Zaher, AA; Mahrouse, MA; Moussa, BA	1
Boschmann, M; Dahlke, M; Danser, AHJ; Dole, WP; Engeli, S; Jordan, J; May, M; Nussberger, J; Pal, P; Prescott, MF; Stitah, S	1
Pathak, AS; Rojas, M; Stouffer, GA	1

Reviews

9 review(s) available for amlodipine and aliskiren

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Combination therapy with aliskiren and amlodipine in hypertension: treatment rationale and clinical results. Expert review of cardiovascular therapy, 2011, Volume: 9, Issue:4 Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Fumarates; Humans; Hypertension; Treatment Outcome	2011
In brief: Another three-drug combination for hypertension. The Medical letter on drugs and therapeutics, 2011, Apr-04, Volume: 53, Issue:1361 Topics: Amides; Amlodipine; Animals; Drug Approval; Drug Combinations; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Tablets; United States	2011
Combined aliskiren-amlodipine treatment for hypertension in African Americans: clinical science and management issues. Therapeutic advances in cardiovascular disease, 2011, Volume: 5, Issue:3 Topics: Amides; Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Fumarates; Humans; Hypertension; Patient Selection; Practice Guidelines as Topic; Precision Medicine; Treatment Outcome; United States	2011
Single-pill triple-combination therapy: an alternative to multiple-drug treatment of hypertension. Postgraduate medicine, 2011, Volume: 123, Issue:6 Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Design; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tetrazoles; Valine; Valsartan	2011
Aliskiren, amlodipine and hydrochlorothiazide triple combination for hypertension. Expert review of cardiovascular therapy, 2012, Volume: 10, Issue:3 Topics: Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Treatment Outcome	2012
The single pill triple combination of aliskiren, amlodipine, and hydrochlorothiazide in the treatment of hypertension. Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:16 Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Treatment Outcome	2012
Aliskiren and amlodipine in the management of essential hypertension: meta-analysis of randomized controlled trials. PloS one, 2013, Volume: 8, Issue:7 Topics: Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Fumarates; Humans; Hypertension; Obesity; Publication Bias; Randomized Controlled Trials as Topic	2013
Aliskiren/amlodipine vs. aliskiren/hydrochlorothiazide in hypertension: indirect meta-analysis of trials comparing the two combinations vs. monotherapy. American journal of hypertension, 2014, Volume: 27, Issue:2 Topics: Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Renin	2014

Trials

26 trial(s) available for amlodipine and aliskiren

Article	Year
Direct Renin inhibition with aliskiren in obese patients with arterial hypertension. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:5 Topics: Administration, Oral; Adult; Aged; Amides; Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diastole; Double-Blind Method; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Obesity; Renin; Systole; Tetrazoles; Treatment Outcome	2007
Antihypertensive efficacy of the oral direct renin inhibitor aliskiren as add-on therapy in patients not responding to amlodipine monotherapy. Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:10 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Male; Middle Aged; Renin	2007
Efficacy and tolerability of aliskiren 300 mg/hydrochlorothiazide 25 mg (± amlodipine 5 mg) in hypertensive patients not controlled by candesartan 32 mg plus HCT 25 mg. Current medical research and opinion, 2011, Volume: 27, Issue:1 Topics: Adult; Aged; Algorithms; Amides; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Failure; Treatment Outcome	2011
Aliskiren and the calcium channel blocker amlodipine combination as an initial treatment strategy for hypertension control (ACCELERATE): a randomised, parallel-group trial. Lancet (London, England), 2011, Jan-22, Volume: 377, Issue:9762 Topics: Amides; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Diastole; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Systole	2011
Effect of aliskiren addition to amlodipine on ankle edema in hypertensive patients: a three-way crossover study. Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:9 Topics: Amides; Amlodipine; Ankle; Ankle Joint; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Edema; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Prospective Studies; Renin; Renin-Angiotensin System	2011
Peripheral and central blood pressure responses of combination aliskiren/hydrochlorothiazide and amlodipine monotherapy in African American patients with stage 2 hypertension: the ATLAAST trial. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:5 Topics: Adult; Amides; Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Brachial Artery; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Headache; Humans; Hydrochlorothiazide; Hypertension; Incidence; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Treatment Outcome	2011
Comparative efficacy and safety of combination aliskiren/amlodipine and amlodipine monotherapy in African Americans with stage 2 hypertension. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:8 Topics: Adult; Amides; Amlodipine; Black or African American; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Edema; Fatigue; Female; Fumarates; Headache; Humans; Hypertension; Incidence; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Treatment Outcome	2011
Aliskiren as add-on therapy in the treatment of hypertensive diabetic patients inadequately controlled with valsartan/HCT combination: a placebo-controlled study. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2011, Oct-01, Volume: 11, Issue:5 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Dropouts; Potassium; Single-Blind Method	2011
Effects of aliskiren on QT duration and dispersion in hypertensive patients with type 2 diabetes mellitus. Diabetes, obesity & metabolism, 2012, Volume: 14, Issue:4 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Electrocardiography; Female; Fumarates; Heart Conduction System; Humans; Hypertension; Long QT Syndrome; Male; Middle Aged; Prospective Studies	2012
Efficacy and tolerability of the single-pill combination of aliskiren 300 mg/amlodipine 10 mg in hypertensive patients not controlled by olmesartan 40 mg/amlodipine 10 mg. Current medical research and opinion, 2012, Volume: 28, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Resistance; Drug Substitution; Female; Fumarates; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tablets; Tetrazoles; Treatment Failure; Treatment Outcome; Young Adult	2012
Comparison of aliskiren/hydrochlorothiazide combination therapy and amlodipine monotherapy in patients with stage 2 systolic hypertension and type 2 diabetes mellitus. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:12 Topics: Amides; Amlodipine; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Systole	2011
Aliskiren penetrates adipose and skeletal muscle tissue and reduces renin-angiotensin system activity in obese hypertensive patients. Journal of hypertension, 2012, Volume: 30, Issue:3 Topics: Adipose Tissue; Adult; Amides; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Extracellular Fluid; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Muscle, Skeletal; Obesity; Pilot Projects; Renin-Angiotensin System	2012
Antihypertensive efficacy and tolerability of aliskiren/amlodipine single- pill combinations in patients with an inadequate response to aliskiren monotherapy. Current vascular pharmacology, 2012, Volume: 10, Issue:6 Topics: Administration, Oral; Adult; Aged; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Resistance; Europe; Female; Fumarates; Humans; Hypertension; India; Least-Squares Analysis; Logistic Models; Male; Middle Aged; Republic of Korea; Tablets; Time Factors; Treatment Outcome; Vasodilator Agents; Venezuela	2012
Efficacy and tolerability of aliskiren/amlodipine single-pill combinations in patients who did not respond fully to amlodipine monotherapy¥. Current vascular pharmacology, 2012, Volume: 10, Issue:6 Topics: Administration, Oral; Adult; Aged; Amides; Amlodipine; Antihypertensive Agents; Argentina; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Resistance; Europe; Female; Fumarates; Humans; Hypertension; Logistic Models; Male; Middle Aged; Tablets; Time Factors; Treatment Outcome; Turkey; Vasodilator Agents	2012
Additive renoprotective effects of aliskiren on angiotensin receptor blocker and calcium channel blocker treatments for type 2 diabetic patients with albuminuria. Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:8 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Albuminuria; Aldosterone; Amides; Amlodipine; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Deoxyguanosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fatty Acid-Binding Proteins; Female; Fumarates; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Male; Middle Aged; Renin; Telmisartan; Young Adult	2012
Clinic and ambulatory blood pressure lowering effect of aliskiren/amlodipine/hydrochlorothiazide combination in patients with moderate-to-severe hypertension: a randomized active-controlled trial. Journal of hypertension, 2012, Volume: 30, Issue:10 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Severity of Illness Index; Single-Blind Method	2012
Treatment with aliskiren/amlodipine combination in patients with moderate-to-severe hypertension: a randomised, double-blind, active comparator trial. International journal of clinical practice, 2012, Volume: 66, Issue:9 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Treatment Outcome	2012
Efficacy and safety of aliskiren and amlodipine combination therapy in patients with hypertension: a randomized, double-blind, multifactorial study. Journal of human hypertension, 2013, Volume: 27, Issue:5 Topics: Adult; Aged; Amides; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Renin	2013
Safety and efficacy of aliskiren/amlodipine/hydrochlorothiazide triple combination in patients with moderate to severe hypertension: a 54-week, open-label study. Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:12 Topics: Adult; Aged; Amides; Amlodipine; Antihypertensive Agents; Biological Availability; Blood Pressure; Drug Monitoring; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Pharmacovigilance; Severity of Illness Index; Treatment Outcome	2012
Effects of direct renin inhibition on atherosclerotic biomarkers in patients with stable coronary artery disease and type 2 diabetes mellitus. Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:5 Topics: Aged; Amides; Amlodipine; Atherosclerosis; Biomarkers; Blood Pressure; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Fumarates; Humans; Male; Middle Aged; Prospective Studies; Renin	2013
Differential effects of aliskiren/amlodipine combination and high-dose amlodipine monotherapy on endothelial function in elderly hypertensive patients. American journal of hypertension, 2014, Volume: 27, Issue:1 Topics: Aged; Aged, 80 and over; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Endothelium, Vascular; Female; Fumarates; Humans; Hypertension; Japan; Male; Renin; Time Factors; Treatment Outcome; Vasodilation; Vasodilator Agents	2014
Effect of aliskiren in chronic kidney disease patients with refractory hypertension undergoing hemodialysis: a randomized controlled multicenter study. Clinical and experimental nephrology, 2014, Volume: 18, Issue:5 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Female; Fumarates; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis	2014
The effect of aliskiren versus ramipril-based treatment on the Ambulatory Arterial Stiffness Index in hypertensive patients. International angiology : a journal of the International Union of Angiology, 2014, Volume: 33, Issue:1 Topics: Adult; Aged; Amides; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Drug Therapy, Combination; Fumarates; Greece; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Predictive Value of Tests; Ramipril; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Time Factors; Treatment Outcome; Vascular Stiffness; Vasodilator Agents	2014
Aliskiren alone or with other antihypertensives in the elderly with borderline and stage 1 hypertension: the APOLLO trial. European heart journal, 2014, Volume: 35, Issue:26 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Medication Adherence; Potassium; Treatment Outcome	2014
Differing Effects of Aliskiren/Amlodipine Combination and High-Dose Amlodipine Monotherapy on Ambulatory Blood Pressure and Target Organ Protection. Journal of clinical hypertension (Greenwich, Conn.), 2016, Volume: 18, Issue:1 Topics: Aged; Aged, 80 and over; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Creatinine; Drug Therapy, Combination; Female; Fumarates; Humans; Hypertension; Japan; Male; Organ Sparing Treatments; Prospective Studies; Renin; Serum Albumin	2016
Systemic and tissue-specific effects of aliskiren on the RAAS and carbohydrate/lipid metabolism in obese patients with hypertension. Journal of the American Society of Hypertension : JASH, 2017, Volume: 11, Issue:8 Topics: Adipose Tissue; Adult; Amides; Amlodipine; Angiotensin II; Antihypertensive Agents; Blood Glucose; Double-Blind Method; Female; Fumarates; Glucose; Humans; Hypertension; Insulin; Lipolysis; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Obesity; Renin; Renin-Angiotensin System	2017

Other Studies

25 other study(ies) available for amlodipine and aliskiren

Article	Year
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers. International journal of clinical practice, 2006, Volume: 60, Issue:11 Topics: Adolescent; Adult; Amides; Amlodipine; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2006
Renin inhibition by aliskiren prevents atherosclerosis progression: comparison with irbesartan, atenolol, and amlodipine. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:5 Topics: Amides; Amlodipine; Animals; Antihypertensive Agents; Apolipoproteins E; Atenolol; Atherosclerosis; Biphenyl Compounds; Blood Pressure; Cholesterol; Disease Models, Animal; Disease Progression; Female; Fumarates; Heart Rate; Irbesartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Renin; Renin-Angiotensin System; Tetrazoles	2008
Aliskiren for hypertension in adults. Drug and therapeutics bulletin, 2008, Volume: 46, Issue:10 Topics: Adult; Amides; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Combinations; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Renin; Treatment Outcome	2008
Long-term safety, tolerability and efficacy of combination therapy with aliskiren and amlodipine in patients with hypertension. Current medical research and opinion, 2009, Volume: 25, Issue:4 Topics: Adult; Aged; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Drug Therapy, Combination; Drug Tolerance; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Patient Selection; Safety; Systole	2009
Aliskiren/amlodipine (Tekamlo): another combination tablet for hypertension. The Medical letter on drugs and therapeutics, 2010, Nov-29, Volume: 52, Issue:1352 Topics: Amides; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Drug Interactions; Fumarates; Humans; Hypertension; Randomized Controlled Trials as Topic; Renin	2010
Initial combination antihypertensives: let's ACCELERATE. Lancet (London, England), 2011, Jan-22, Volume: 377, Issue:9762 Topics: Amides; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Fumarates; Humans; Hypertension; Practice Guidelines as Topic; Randomized Controlled Trials as Topic	2011
Initial combination therapy for treatment of hypertension. Lancet (London, England), 2011, Apr-30, Volume: 377, Issue:9776 Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Fumarates; Humans; Hypertension; Neoplasms; Renin	2011
Initial combination therapy for treatment of hypertension. Lancet (London, England), 2011, Apr-30, Volume: 377, Issue:9776 Topics: Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Fumarates; Humans; Hypertension	2011
Initial combination therapy for treatment of hypertension. Lancet (London, England), 2011, Apr-30, Volume: 377, Issue:9776 Topics: Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Fumarates; Humans; Hypertension	2011
[A powerful duo: antihypertensives aliskiren and amlodipine in one tablet. Combination tablet for hypertensive patients with diabetes and overweight]. MMW Fortschritte der Medizin, 2011, May-12, Volume: 153, Issue:19 Topics: Amides; Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Fumarates; Humans; Hypertension; Overweight	2011
Aliskiren/amlodipine combination for the treatment of hypertension. Drugs of today (Barcelona, Spain : 1998), 2011, Volume: 47, Issue:6 Topics: Amides; Amlodipine; Antihypertensive Agents; Clinical Trials as Topic; Drug Combinations; Drug Interactions; Fumarates; Humans; Hypertension; Renin	2011
Combined aliskiren and amlodipine reduce albuminuria via reduction in renal inflammation in diabetic rats. Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:3 Topics: Albuminuria; Amides; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Fumarates; Hydrochlorothiazide; Inflammation; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin; Streptozocin	2012
Amlodidine + aliskiren. Prescrire international, 2012, Volume: 21, Issue:129 Topics: Amides; Amlodipine; Drug Combinations; Fumarates; Humans; Hypertension	2012
Reduction of aldosterone production improves renal oxidative stress and fibrosis in diabetic rats. Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:1 Topics: Aldosterone; Amides; Amlodipine; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cyclic GMP; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dinoprost; Down-Regulation; Fibronectins; Fibrosis; Fumarates; Immunohistochemistry; Kidney; Male; Natriuresis; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Time Factors	2013
Editorial: aliskiren/amlodipine single-pill combinations: more evidence in favour of combination formulations for the treatment of hypertension. Current vascular pharmacology, 2012, Volume: 10, Issue:6 Topics: Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Fumarates; Humans; Hypertension; Male; Vasodilator Agents	2012
Simultaneous determination of amlodipine and aliskren in tablets by high-performance liquid chromatography. Journal of chromatographic science, 2014, Volume: 52, Issue:7 Topics: Amides; Amlodipine; Chromatography, High Pressure Liquid; Fumarates; Limit of Detection; Reproducibility of Results; Sensitivity and Specificity; Tablets	2014
Simultaneous determination of aliskiren hemifumarate, amlodipine besylate, and hydrochlorothiazide in their triple mixture dosage form by capillary zone electrophoresis. Journal of separation science, 2014, Volume: 37, Issue:9-10 Topics: Amides; Amlodipine; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Fumarates; Hydrochlorothiazide	2014
Steady-state and synchronous spectrofluorimetric methods for simultaneous determination of aliskiren hemifumarate and amlodipine besylate in dosage forms. Luminescence : the journal of biological and chemical luminescence, 2014, Volume: 29, Issue:7 Topics: Amides; Amlodipine; Chemistry, Pharmaceutical; Fumarates; Molecular Structure; Spectrometry, Fluorescence	2014
Development and validation of a HPLC-PDA bioanalytical method for the simultaneous estimation of Aliskiren and Amlodipine in human plasma. Biomedical chromatography : BMC, 2015, Volume: 29, Issue:3 Topics: Acetonitriles; Amides; Amlodipine; Chemical Precipitation; Chromatography, High Pressure Liquid; Drug Stability; Fumarates; Humans; Hydrochlorothiazide; Limit of Detection; Sensitivity and Specificity	2015
Simultaneous Determination of Aliskiren Hemifumarate, Amlodipine Besylate and Hydrochlorothiazide in Spiked Human Plasma Using UPLC-MS/MS. Journal of chromatographic science, 2015, Volume: 53, Issue:7 Topics: Amides; Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Fumarates; Humans; Hydrochlorothiazide; Limit of Detection; Liquid-Liquid Extraction; Reproducibility of Results; Tandem Mass Spectrometry	2015
Efficacy, safety, and tolerability of antihypertensive therapy with aliskiren/amlodipine in clinical practice in Austria. The RALLY (Rasilamlo long lasting efficacy) study. Wiener klinische Wochenschrift, 2015, Volume: 127, Issue:5-6 Topics: Aged; Aged, 80 and over; Amides; Amlodipine; Antihypertensive Agents; Austria; Drug Combinations; Female; Fumarates; Humans; Hypertension; Longitudinal Studies; Male; Middle Aged; Treatment Outcome	2015
Continuous Wavelet Transform, a powerful alternative to Derivative Spectrophotometry in analysis of binary and ternary mixtures: A comparative study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Dec-05, Volume: 151 Topics: Algorithms; Amides; Amlodipine; Bisoprolol; Complex Mixtures; Fumarates; Hydrochlorothiazide; Reproducibility of Results; Signal Processing, Computer-Assisted; Signal-To-Noise Ratio; Spectrophotometry; Wavelet Analysis	2015
Mean centering of double divisor ratio spectra, a novel spectrophotometric method for analysis of ternary mixtures. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, Jan-15, Volume: 153 Topics: Amides; Amlodipine; Analysis of Variance; Chromatography, High Pressure Liquid; Fumarates; Hydrochlorothiazide; Methanol; Models, Molecular; Reference Standards; Reproducibility of Results; Spectrophotometry; Tablets	2016
Resolution of overlapped spectra for the determination of ternary mixture using different and modified spectrophotometric methods. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, Aug-05, Volume: 165 Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Fumarates; Hydrochlorothiazide; Spectrophotometry, Ultraviolet; Tablets	2016
Expression of Cyr61 in ApoE Scientific reports, 2021, 02-11, Volume: 11, Issue:1 Topics: Amides; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Apolipoproteins E; Blood Pressure; Cysteine-Rich Protein 61; Fumarates; Gene Expression Regulation; Humans; Hypertension; Irbesartan; Mice; Mice, Knockout; Renal Artery; Renal Artery Obstruction	2021