amitrole and buthionine sulfoximine

amitrole has been researched along with buthionine sulfoximine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.29)18.7374
1990's17 (48.57)18.2507
2000's12 (34.29)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inoue, S; Ito, K; Kawanishi, S; Yamamoto, K1
Cheeks, L; Green, K; Hull, DS; Pendarvis, RW1
Costarides, AP; Green, K; Riley, MV2
Elwell, JH; Harrison, DG; Mügge, A; Peterson, TE1
Costarides, AP; Green, K; Nelson, E1
Cheeks, L; Green, K; Greiff, M1
Costarides, A; Green, K; Recasens, JF; Riley, MV1
DeHart, PD; Nadeau, DM; Simon, RH1
Michiels, C; Remacle, J1
Dean, RT; Vince, GS1
Hasegawa, R; Kurokawa, Y; Sai-Kato, K; Takagi, A; Tanimura, A; Umemura, T1
Averill-Bates, DA; Przybytkowski, E2
Zdolsek, JM1
Ben-Yoseph, O; Boxer, PA; Ross, BD1
Masaki, H; Okano, Y; Sakurai, H1
Kirschbaum, J; Peterson, MW1
Shaikh, ZA; Vu, TT; Zaman, K1
Averill, DA; Lord-Fontaine, S1
Hiraishi, H; Ivey, KJ; Shimada, T; Terano, A1
Hassinen, I; Kahlos, K; Kinnula, VL; Linnainmaa, K; Pitkänen, S1
Bleau, AM; du Souich, P; Dumont, I; El-Kadi, AO; Maurice, H1
Oliveira, MB; Oliveira, PL; Paes, MC1
Chan, C; Goldkorn, T; Kawcak, T; Lavrentiadou, SN; Rasooly, R; Ravid, T; Tsaba, A; van der Vliet, A1
Fricker, MD; Meyer, AJ1
Dorval, J; Hontela, A1
Colpaert, EE; De Backer, O; Lefebvre, RA1
Burke, JM; Eells, JT; Henry, MM; Skumatz, CM; Treichel, JL1
Kim, HW; Kim, YH; Lee, EH; Lee, HK; Lee, JW; Seo, YJ1
Chen, X; Connors, SG; Mendonca, M; Patel, K; Welch, WJ; Wilcox, CS1
Ferreira, AC; Klumb, CE; Kwee, JK; Luque, DG; Maia, RC; Silva, KL; Vasconcelos, FC1
Han, YH; Park, WH1
Jang, HD; Kim, GN1
Biswas, S; Byrd, JC; Jarjoura, D; Mo, X; Mone, AP; Muthusamy, N; Vargo, M; Zhao, X1

Other Studies

35 other study(ies) available for amitrole and buthionine sulfoximine

ArticleYear
Caffeic acid causes metal-dependent damage to cellular and isolated DNA through H2O2 formation.
    Carcinogenesis, 1992, Volume: 13, Issue:9

    Topics: Amitrole; Autoradiography; Buthionine Sulfoximine; Caffeic Acids; Catalase; Cells, Cultured; DNA Damage; Electrophoresis, Agar Gel; Electrophoresis, Gel, Pulsed-Field; Free Radical Scavengers; Humans; Hydrogen Peroxide; Metals; Methionine Sulfoximine; Phenanthrolines; Proto-Oncogenes; Spectrophotometry, Ultraviolet

1992
Hydrogen peroxide effects on ionic and non-ionic permeability of the rabbit corneal endothelium.
    Lens and eye toxicity research, 1991, Volume: 8, Issue:1

    Topics: Amitrole; Animals; Antimetabolites; Bicarbonates; Buthionine Sulfoximine; Catalase; Dextrans; Endothelium, Corneal; Glutathione; Hydrogen Peroxide; Inulin; Methionine Sulfoximine; Permeability; Rabbits; Sodium

1991
Roles of catalase and the glutathione redox cycle in the regulation of anterior-chamber hydrogen peroxide.
    Ophthalmic research, 1991, Volume: 23, Issue:5

    Topics: Amitrole; Animals; Anterior Chamber; Anterior Eye Segment; Antimetabolites; Aqueous Humor; Ascorbic Acid; Buthionine Sulfoximine; Carmustine; Catalase; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Methionine Sulfoximine; Oxidation-Reduction; Rabbits

1991
Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Acetylcholine; Amitrole; Animals; Bradykinin; Buthionine Sulfoximine; Calcimycin; Catalase; Cells, Cultured; Coronary Vessels; Ditiocarb; Endothelium, Vascular; Female; Glutathione; In Vitro Techniques; Male; Methionine Sulfoximine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Rabbits; Superoxide Dismutase; Swine; Vasodilation

1991
Morphological sequelae of intracameral hydrogen peroxide after inhibition of glutathione synthesis.
    Lens and eye toxicity research, 1991, Volume: 8, Issue:4

    Topics: Amitrole; Animals; Antimetabolites; Aqueous Humor; Buthionine Sulfoximine; Catalase; Endothelium, Corneal; Glutathione; Hydrogen Peroxide; Injections, Intravenous; Methionine Sulfoximine; Oxidation-Reduction; Rabbits; Vitreous Body

1991
Role of glutathione in the regulation of anterior chamber hydrogen peroxide.
    Lens and eye toxicity research, 1990, Volume: 7, Issue:3-4

    Topics: Amitrole; Animals; Anterior Chamber; Antimetabolites; Buthionine Sulfoximine; Carmustine; Catalase; Ciliary Body; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Iris; Methionine Sulfoximine; Oxidation-Reduction; Rabbits

1990
Influence of hydrogen peroxide on adenine uptake by iris, ciliary epithelium and corneal endothelium.
    Lens and eye toxicity research, 1989, Volume: 6, Issue:3

    Topics: Adenine; Aging; Amitrole; Animals; Anterior Chamber; Buthionine Sulfoximine; Catalase; Ciliary Body; Endothelium, Corneal; Epithelium; Glutathione; Hydrogen Peroxide; Iris; Methionine Sulfoximine; Rabbits

1989
The effects of ascorbate, 3-aminotriazole, and 1,3-bis-(2-chloroethyl)-1-nitrosourea on hydrogen peroxide levels in the rabbit aqueous humor.
    Lens and eye toxicity research, 1989, Volume: 6, Issue:1-2

    Topics: Amitrole; Animals; Aqueous Humor; Ascorbic Acid; Buthionine Sulfoximine; Carmustine; Catalase; Ciliary Body; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Iris; Methionine Sulfoximine; Rabbits

1989
Resistance of rat pulmonary alveolar epithelial cells to neutrophil- and oxidant-induced injury.
    American journal of respiratory cell and molecular biology, 1989, Volume: 1, Issue:3

    Topics: Amitrole; Animals; Azides; Buthionine Sulfoximine; Carmustine; Catalase; Cells, Cultured; Epithelium; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen Peroxide; Methionine Sulfoximine; Neutrophils; Oxidation-Reduction; Pulmonary Alveoli; Rats; Rats, Inbred F344

1989
Use of the inhibition of enzymatic antioxidant systems in order to evaluate their physiological importance.
    European journal of biochemistry, 1988, Nov-01, Volume: 177, Issue:2

    Topics: Amitrole; Buthionine Sulfoximine; Carmustine; Catalase; Cell Survival; Ditiocarb; Fibroblasts; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Methionine Sulfoximine; Superoxide Dismutase; Thiomalates

1988
Is enhanced free radical flux associated with increased intracellular proteolysis?
    FEBS letters, 1987, Jun-01, Volume: 216, Issue:2

    Topics: Amitrole; Animals; Buthionine Sulfoximine; Cell Line; Cells, Cultured; Diamide; Ditiocarb; Dose-Response Relationship, Radiation; Fibroblasts; Free Radicals; Gamma Rays; Hydrolysis; Macrophages; Methionine Sulfoximine; Mice; Phenylhydrazines; Proteins; Superoxide Dismutase

1987
Pentachlorophenol-induced oxidative DNA damage in mouse liver and protective effect of antioxidants.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amitrole; Animals; Antioxidants; Buthionine Sulfoximine; Deoxyguanosine; DNA Damage; Liver; Male; Methionine Sulfoximine; Mice; Oxidation-Reduction; Pentachlorophenol; Time Factors

1995
The role of glucose in cellular defences against cytotoxicity of hydrogen peroxide in Chinese hamster ovary cells.
    Archives of biochemistry and biophysics, 1994, Volume: 312, Issue:1

    Topics: Amitrole; Animals; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Catalase; Cell Survival; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Glucose; Glutathione; Hydrogen Peroxide; Methionine Sulfoximine; Pentose Phosphate Pathway

1994
Acridine orange-mediated photodamage to cultured cells.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1993, Volume: 101, Issue:2

    Topics: Acridine Orange; Amitrole; Animals; Azides; Buthionine Sulfoximine; Cathepsin L; Cathepsins; Cell Death; Cysteine Endopeptidases; Cytosol; Deferoxamine; Endopeptidases; Glutathione; Histiocytoma, Benign Fibrous; L-Lactate Dehydrogenase; Light; Lysosomes; Methionine Sulfoximine; Mice; Oxygen; Partial Pressure; Photosensitizing Agents; Radiation-Sensitizing Agents; Sodium Azide; Tumor Cells, Cultured

1993
Correlation between glutathione and stimulation of the pentose phosphate cycle in situ in Chinese hamster ovary cells exposed to hydrogen peroxide.
    Archives of biochemistry and biophysics, 1996, Jan-01, Volume: 325, Issue:1

    Topics: Amitrole; Animals; Buthionine Sulfoximine; Carmustine; CHO Cells; Cricetinae; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Glutamate-Cysteine Ligase; Glutathione; Hydrogen Peroxide; Kinetics; Methionine Sulfoximine; Oxidation-Reduction; Paraquat; Pentose Phosphate Pathway

1996
Assessment of the role of the glutathione and pentose phosphate pathways in the protection of primary cerebrocortical cultures from oxidative stress.
    Journal of neurochemistry, 1996, Volume: 66, Issue:6

    Topics: Amitrole; Animals; Buthionine Sulfoximine; Carcinogens; Catalase; Cell Death; Cells, Cultured; Cerebral Cortex; Chelating Agents; Deferoxamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Glutamate-Cysteine Ligase; Glutathione; Hydrogen Peroxide; Iron; Lactates; Lactic Acid; Methionine Sulfoximine; Neuroglia; Neurons; Neuroprotective Agents; Oxidative Stress; Pentose Phosphate Pathway; Rats; Siderophores; Succimer

1996
Differential role of catalase and glutathione peroxidase in cultured human fibroblasts under exposure of H2O2 or ultraviolet B light.
    Archives of dermatological research, 1998, Volume: 290, Issue:3

    Topics: Amitrole; Buthionine Sulfoximine; Catalase; Cells, Cultured; Drug Resistance; Enzyme Inhibitors; Fibroblasts; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Oxidative Stress; Radiation Tolerance; Skin; Ultraviolet Rays

1998
Asbestos-induced lung epithelial permeability: potential role of nonoxidant pathways.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Amitrole; Asbestos, Amosite; Asbestos, Serpentine; Buthionine Sulfoximine; Catalase; Cell Membrane Permeability; Cells, Cultured; Epithelial Cells; Glutathione; Humans; Hydrogen Peroxide; Kinetics; Lung; Mannitol; Oxidants; Phorbol 12,13-Dibutyrate; Pulmonary Fibrosis; Time Factors; Vitamin K

1998
Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants.
    Toxicology and applied pharmacology, 1999, Feb-01, Volume: 154, Issue:3

    Topics: Acetylcysteine; Alanine Transaminase; Amitrole; Animals; Anti-Inflammatory Agents; Antioxidants; Buthionine Sulfoximine; Cadmium; Cysteine; Drug Combinations; Enzyme Inhibitors; Female; Glutathione; Glycine; Glycyrrhetinic Acid; Kidney; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Malondialdehyde; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Steroids; Time Factors; Vitamin E

1999
Enhancement of cytotoxicity of hydrogen peroxide by hyperthermia in chinese hamster ovary cells: role of antioxidant defenses.
    Archives of biochemistry and biophysics, 1999, Mar-15, Volume: 363, Issue:2

    Topics: Acetylcysteine; Amitrole; Animals; Antioxidants; Buthionine Sulfoximine; Catalase; Cell Survival; CHO Cells; Cricetinae; Enzyme Inhibitors; Glutathione; Hot Temperature; Hydrogen Peroxide; Intracellular Fluid; Mesna; Oxidation-Reduction; Protective Agents; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1999
Role of antioxidant defenses against ethanol-induced damage in cultured rat gastric epithelial cells.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:1

    Topics: Amitrole; Animals; Antioxidants; Buthionine Sulfoximine; Carmustine; Catalase; Cells, Cultured; Chromium Radioisotopes; Endothelium; Enzyme Inhibitors; Epithelial Cells; Ethanol; Female; Gastric Mucosa; Glutathione; Male; NADH Dehydrogenase; Oxidation-Reduction; Rats; Superoxides

1999
Generation of reactive oxygen species by human mesothelioma cells.
    British journal of cancer, 1999, Volume: 80, Issue:1-2

    Topics: Amitrole; Buthionine Sulfoximine; Citrate (si)-Synthase; Electron Transport Complex IV; Humans; Mesothelioma; Mitochondria; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured

1999
Role of reactive oxygen intermediates in the decrease of hepatic cytochrome P450 activity by serum of humans and rabbits with an acute inflammatory reaction.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:9

    Topics: Acute-Phase Reaction; Amitrole; Animals; Biotransformation; Buthionine Sulfoximine; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Humans; Hydrogen Peroxide; Liver; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Rabbits; Reactive Oxygen Species; Theophylline; Thiourea

2000
Hydrogen peroxide detoxification in the midgut of the blood-sucking insect, Rhodnius prolixus.
    Archives of insect biochemistry and physiology, 2001, Volume: 48, Issue:2

    Topics: Amitrole; Animals; Buthionine Sulfoximine; Catalase; Digestive System; Enzyme Inhibitors; Female; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Reduviidae; Superoxide Dismutase

2001
Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione.
    American journal of respiratory cell and molecular biology, 2001, Volume: 25, Issue:6

    Topics: Acetylcysteine; Amitrole; Annexin A5; Antioxidants; Apoptosis; Bronchi; Buthionine Sulfoximine; Catalase; Cells, Cultured; Ceramides; Diacylglycerol Kinase; Dithiothreitol; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; In Situ Nick-End Labeling; Mercaptoethanol; Microscopy, Fluorescence; Oxidation-Reduction; Oxidative Stress; Pulmonary Alveoli; Reactive Oxygen Species; Trachea

2001
Control of demand-driven biosynthesis of glutathione in green Arabidopsis suspension culture cells.
    Plant physiology, 2002, Volume: 130, Issue:4

    Topics: Amitrole; Arabidopsis; Buthionine Sulfoximine; Cadmium; Cells, Cultured; Cyclopentanes; Enzyme Inhibitors; Fluorescent Dyes; Glutathione; Oxylipins; Protein Biosynthesis; Pyrazoles; Sulfates; Transcription, Genetic; Vitamin K 3

2002
Role of glutathione redox cycle and catalase in defense against oxidative stress induced by endosulfan in adrenocortical cells of rainbow trout (Oncorhynchus mykiss).
    Toxicology and applied pharmacology, 2003, Oct-15, Volume: 192, Issue:2

    Topics: Acetylcysteine; Adrenal Cortex; Amitrole; Animals; Buthionine Sulfoximine; Catalase; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endosulfan; Glutathione; Insecticides; Kidney; Lipid Peroxidation; Lipid Peroxides; Oncorhynchus mykiss; Oxidation-Reduction; Oxidative Stress

2003
Influence of polyethylene-glycol-superoxide dismutase and combined depletion and repletion of antioxidants on nitrergic relaxation in the pig gastric fundus.
    European journal of pharmacology, 2004, Feb-20, Volume: 486, Issue:2

    Topics: Aminoquinolines; Amitrole; Animals; Antioxidants; Buthionine Sulfoximine; Catalase; Ditiocarb; Electric Stimulation; Free Radical Scavengers; Gastric Fundus; Hydroxocobalamin; In Vitro Techniques; Male; Muscle, Smooth; Nitric Oxide; Polyethylene Glycols; Superoxide Dismutase; Swine

2004
Antioxidants and ocular cell type differences in cytoprotection from formic acid toxicity in vitro.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 82, Issue:1

    Topics: Amitrole; Antioxidants; Buthionine Sulfoximine; Catalase; Cells, Cultured; Cytoprotection; Drug Combinations; Enzyme Inhibitors; Formates; Glutathione; Glutathione Peroxidase; Humans; Photoreceptor Cells; Pigment Epithelium of Eye

2004
Role of glutathione in the adaptive tolerance to H2O2.
    Free radical biology & medicine, 2004, Oct-15, Volume: 37, Issue:8

    Topics: Amitrole; Animals; Buthionine Sulfoximine; Catalase; Cell Line; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Hydrogen Peroxide; Myocytes, Cardiac; Oxidation-Reduction; Oxidative Stress; Rats

2004
Acute antihypertensive action of Tempol in the spontaneously hypertensive rat.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6

    Topics: Amitrole; Animals; Antihypertensive Agents; Blood Pressure; Buthionine Sulfoximine; Catalase; Cromakalim; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglionic Blockers; Glutathione Peroxidase; Glyburide; Heart Rate; Heme Oxygenase (Decyclizing); Hexamethonium; Hypertension; Infusions, Intravenous; KATP Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptides; Potassium Channel Blockers; Rats; Rats, Inbred SHR; Spin Labels; Sympathetic Nervous System; Time Factors

2007
Modulation of reactive oxygen species by antioxidants in chronic myeloid leukemia cells enhances imatinib sensitivity through survivin downregulation.
    Anti-cancer drugs, 2008, Volume: 19, Issue:10

    Topics: Amitrole; Antineoplastic Agents; Antioxidants; Benzamides; Buthionine Sulfoximine; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Imatinib Mesylate; Inhibitor of Apoptosis Proteins; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Microtubule-Associated Proteins; Neoplasm Proteins; Piperazines; Pyrimidines; Reactive Oxygen Species; Survivin

2008
The effects of N-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione.
    Oncology reports, 2009, Volume: 22, Issue:2

    Topics: Acetylcysteine; Adenocarcinoma; Amitrole; Antimycin A; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Reactive Oxygen Species

2009
Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells.
    Annals of the New York Academy of Sciences, 2009, Volume: 1171

    Topics: Amitrole; Antioxidants; Apoptosis; Buthionine Sulfoximine; Carmustine; Catalase; Cell Line, Tumor; Cell Survival; Chelating Agents; Copper; Dose-Response Relationship, Drug; Glutathione; Humans; Hydrogen Peroxide; Oxidative Stress; Quercetin; Reactive Oxygen Species; Rutin

2009
Arsenic trioxide and ascorbic acid demonstrate promising activity against primary human CLL cells in vitro.
    Leukemia research, 2010, Volume: 34, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Amitrole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arsenic Trioxide; Arsenicals; Ascorbic Acid; B-Lymphocytes; Buthionine Sulfoximine; Catalase; Cell Line, Tumor; Cysteine Proteases; Cysteine Proteinase Inhibitors; Drug Evaluation, Preclinical; Drug Synergism; Enzyme Activation; Glutathione; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Proteins; Oxidants; Oxidative Stress; Oxides; Reactive Oxygen Species

2010