amitriptyline and topiramate

amitriptyline has been researched along with topiramate in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (24.39)29.6817
2010's24 (58.54)24.3611
2020's7 (17.07)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Mannix, LK1
Peres, MF; Vieira, DS1
Aydinli, I; Keskinbora, K1
Eshraghi, Y; Gosain, AK; Kung, TA; Scher, MS; Totonchi, A1
Quimbo, RM; Rupnow, MF; Wertz, DA; Yaldo, AZ1
Banks, J; Biondi, D; Dodick, DW; Freitag, F; Greenberg, SJ; Hulihan, J; Rupnow, M; Saper, J; Xiang, J1
Bigal, ME; Biondi, DM; Hulihan, J; Lipton, RB; Xiang, J1
Firnhaber, JM; Rickett, K1
Tanganelli, P; Valguarnera, F1
Gaul, C; Straube, A1
Pascual, J1
Alehan, F; Kandemir, H; Sezer, T1
Chamberlin, LA; Coffey, CS; Eklund, DD; Hershey, AD; Korbee, LL; Powers, SW1
Dawood, A; Kaufman, KR; Newman, NB1
Chisholm, D; Linde, M; Steiner, TJ1
Ak, S; Atasayar, G; Can, FE; Cecener, G; Egeli, U; Eryilmaz, IE; Karli, N; Taskapilioglu, O; Tezcan, G; Tunca, B; Yildirim, O; Zarifoglu, M1
Haimi-Cohen, Y; Markus, TE; Moad, B; Zeharia, A1
Chamberlin, LA; Coffey, CS; Ecklund, DJ; Hershey, AD; Klingner, EA; Korbee, LL; Porter, LL; Powers, SW; Yankey, JW1
He, A; Li, C; Song, D; Zhang, L1
Dalrymple, RA; Wacogne, I1
Ahmad, S1
Chaput, JP1
Agier, MS; Beau-Salinas, F; Bejan-Angoulvant, T; Bouquet, E; Jonville-Béra, AP; Simon, C; Vrignaud, L1
Bazarsky, A; Kacperski, J1
Isaacs, D1
Patterson-Gentile, C; Szperka, CL1
Hawks, M; Mounsey, A1
Choe, M; Langdon, R; Levyim, D; Pearson, R; Taraman, S1
Álvarez-Morujo de Sande, MG; Bécares-Martínez, C; Domènech-Vadillo, E; Domínguez-Durán, E; González-Aguado, R; Guerra-Jiménez, G; Montilla-Ibáñez, MA1
Chamberlin, LA; Coffey, CS; Ecklund, DJ; Hershey, AD; Kabbouche, MA; Kacperski, J; Klingner, EA; Korbee, LL; Peugh, J; Porter, LL; Powers, SW; Reidy, BL; Yankey, JW1
Oliveira, ABD; Woldeamanuel, YW1
Chamberlin, LA; Coffey, CS; Ecklund, D; Gibler, RC; Hershey, AD; Kabbouche, M; Kacperski, J; Klingner, E; Korbee, LL; Peugh, JL; Porter, LL; Powers, SW; Reidy, BL; Yankey, J1
Alto, M; Giusto, A; Greene, MC; Johnson, RM; Kane, J; Lovero, K; McClendon, J; Nicholson, T; Stockton, M; Tol, WA; Wainberg, ML1
Deligianni, CI; Gil-Gouveia, R; Jassal, T; Lampl, C; MaassenVanDenBrink, A; Reuter, U; Sacco, S; Sanchez-Del-Rio, M; Uluduz, D; Versijpt, J; Zeraatkar, D1
Al-Azzawi, F; Bate, A; Haguinet, F; Mahmoud, I; Sessa, M1

Reviews

11 review(s) available for amitriptyline and topiramate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical advances in the preventive treatment of migraine.
    Acta neurologica Taiwanica, 2004, Volume: 13, Issue:4

    Topics: Amitriptyline; Fructose; Humans; Migraine Disorders; Propranolol; Topiramate; Valproic Acid

2004
Clinical inquiries. What are the best prophylactic drugs for migraine?
    The Journal of family practice, 2009, Volume: 58, Issue:11

    Topics: Adrenergic beta-Antagonists; Amitriptyline; Evidence-Based Medicine; Family Practice; Female; Fructose; Humans; Male; Migraine Disorders; Neuroprotective Agents; Pain Measurement; Practice Guidelines as Topic; Prognosis; Propranolol; Randomized Controlled Trials as Topic; Risk Assessment; Secondary Prevention; Severity of Illness Index; Timolol; Topiramate; Treatment Outcome

2009
[Chronic migraine: treatment].
    Revista de neurologia, 2012, Apr-10, Volume: 54 Suppl 2

    Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antihypertensive Agents; Anxiety; Barbiturates; Botulinum Toxins, Type A; Chronic Disease; Contraindications; Depression; Drug Combinations; Ergot Alkaloids; Fructose; Headache Disorders, Secondary; Humans; Migraine Disorders; Narcotics; Risk Factors; Topiramate; Tryptamines

2012
Capgras delusion with violent behavior in Alzheimer dementia: case analysis with literature review.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2014, Volume: 26, Issue:3

    Topics: Aged; Aggression; Alzheimer Disease; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Capgras Syndrome; Chlordiazepoxide; Fructose; Haloperidol; Humans; Hypnotics and Sedatives; Male; Olanzapine; Potentially Inappropriate Medication List; Renal Insufficiency, Chronic; Topiramate; Violence

2014
Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis.
    The journal of headache and pain, 2017, Volume: 18, Issue:1

    Topics: Adult; Amines; Amitriptyline; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizziness; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Migraine Disorders; Nausea; Pre-Exposure Prophylaxis; Propranolol; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Valproic Acid

2017
New Developments in the Prophylactic Drug Treatment of Pediatric Migraine: What Is New in 2017 and Where Does It Leave Us?
    Current pain and headache reports, 2017, Volume: 21, Issue:8

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Child; Controlled Clinical Trials as Topic; Fructose; Headache Disorders; Humans; Migraine Disorders; Neuroprotective Agents; Topiramate

2017
The Changing Landscape of Pediatric Migraine Therapy: A Review.
    JAMA neurology, 2018, 07-01, Volume: 75, Issue:7

    Topics: Adolescent; Adrenergic beta-Antagonists; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Calcium Channel Blockers; Child; Cognitive Behavioral Therapy; Dihydroergotamine; Dopamine Antagonists; Fluid Therapy; Glucocorticoids; Headache Disorders, Secondary; Humans; Magnesium; Migraine Disorders; Nerve Block; Topiramate; Tryptamines; Valproic Acid

2018
What is the efficacy of aerobic exercise versus strength training in the treatment of migraine? A systematic review and network meta-analysis of clinical trials.
    The journal of headache and pain, 2022, Oct-13, Volume: 23, Issue:1

    Topics: Adult; Amitriptyline; Exercise; Female; Humans; Male; Migraine Disorders; Network Meta-Analysis; Resistance Training; Topiramate

2022
Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low- and middle-income countries.
    The Cochrane database of systematic reviews, 2023, 05-09, Volume: 5

    Topics: Acamprosate; Alcoholism; Amitriptyline; Developing Countries; Disulfiram; Humans; Male; Mirtazapine; Naltrexone; Ondansetron; Topiramate

2023
The comparative effectiveness of migraine preventive drugs: a systematic review and network meta-analysis.
    The journal of headache and pain, 2023, May-19, Volume: 24, Issue:1

    Topics: Adult; Amitriptyline; Antibodies, Monoclonal; Calcitonin Gene-Related Peptide; Gabapentin; Humans; Migraine Disorders; Network Meta-Analysis; Topiramate; Valproic Acid

2023

Trials

9 trial(s) available for amitriptyline and topiramate

ArticleYear
A double-blind randomized controlled trial of topiramate and amitriptyline either alone or in combination for the prevention of migraine.
    Clinical neurology and neurosurgery, 2008, Volume: 110, Issue:10

    Topics: Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Constipation; Disorders of Excessive Somnolence; Double-Blind Method; Drug Therapy, Combination; Female; Fructose; Humans; Male; Middle Aged; Migraine Disorders; Patient Satisfaction; Time Factors; Topiramate; Treatment Outcome; Weight Gain

2008
Topiramate versus amitriptyline in migraine prevention: a 26-week, multicenter, randomized, double-blind, double-dummy, parallel-group noninferiority trial in adult migraineurs.
    Clinical therapeutics, 2009, Volume: 31, Issue:3

    Topics: Adult; Amitriptyline; Body Weight; Central Nervous System Agents; Disability Evaluation; Double-Blind Method; Female; Fructose; Humans; Male; Middle Aged; Migraine Disorders; Patient Satisfaction; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Time Factors; Topiramate; Treatment Outcome; United States

2009
Weight change and clinical markers of cardiovascular disease risk during preventive treatment of migraine.
    Cephalalgia : an international journal of headache, 2009, Volume: 29, Issue:11

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cholesterol, HDL; Double-Blind Method; Female; Fructose; Humans; Male; Migraine Disorders; Risk Factors; Topiramate; Weight Gain; Weight Loss

2009
A randomized trial comparing amitriptyline versus topiramate for the prophylaxis of chronic daily headache in pediatric patients.
    The International journal of neuroscience, 2013, Volume: 123, Issue:8

    Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Child; Double-Blind Method; Female; Fructose; Headache Disorders; Humans; Male; Topiramate

2013
Childhood and Adolescent Migraine Prevention (CHAMP) study: a double-blinded, placebo-controlled, comparative effectiveness study of amitriptyline, topiramate, and placebo in the prevention of childhood and adolescent migraine.
    Headache, 2013, Volume: 53, Issue:5

    Topics: Adolescent; Amitriptyline; Analgesics; Child; Comparative Effectiveness Research; Double-Blind Method; Female; Fructose; Humans; Male; Migraine Disorders; Research Design; Topiramate

2013
Trial of Amitriptyline, Topiramate, and Placebo for Pediatric Migraine.
    The New England journal of medicine, 2017, 01-12, Volume: 376, Issue:2

    Topics: Adolescent; Amitriptyline; Anticonvulsants; Child; Double-Blind Method; Fatigue; Female; Fructose; Humans; Linear Models; Male; Migraine Disorders; Paresthesia; Placebos; Topiramate; Treatment Failure; Xerostomia

2017
Migraine in children.
    Journal of paediatrics and child health, 2018, Volume: 54, Issue:1

    Topics: Adolescent; Amitriptyline; Child; Female; Follow-Up Studies; Humans; Male; Migraine Disorders; Monitoring, Physiologic; Pain Measurement; Patient Safety; Placebos; Primary Prevention; Risk Assessment; Severity of Illness Index; Topiramate; Treatment Outcome

2018
Trajectory of treatment response in the child and adolescent migraine prevention (CHAMP) study: A randomized clinical trial.
    Cephalalgia : an international journal of headache, 2022, Volume: 42, Issue:1

    Topics: Adolescent; Amitriptyline; Child; Double-Blind Method; Headache; Headache Disorders; Humans; Migraine Disorders; Reproducibility of Results; Topiramate; Treatment Outcome

2022
Impact of preventive pill-based treatment on migraine days: A secondary outcome study of the Childhood and Adolescent Migraine Prevention (CHAMP) trial and a comparison of self-report to nosology-derived assessments.
    Headache, 2023, Volume: 63, Issue:6

    Topics: Adolescent; Amitriptyline; Child; Double-Blind Method; Fructose; Headache; Headache Disorders; Humans; Migraine Disorders; Outcome Assessment, Health Care; Self Report; Topiramate; Treatment Outcome

2023

Other Studies

21 other study(ies) available for amitriptyline and topiramate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Tension-type headache with aura.
    Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Bromazepam; Cyclohexanols; Fructose; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Tension-Type Headache; Topiramate; Venlafaxine Hydrochloride; Vision Disorders

2006
Review of pediatric migraine headaches refractory to medical management.
    The Journal of craniofacial surgery, 2009, Volume: 20, Issue:1

    Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Biofeedback, Psychology; Child; Female; Follow-Up Studies; Fructose; Humans; Male; Migraine Disorders; Neuroprotective Agents; Recurrence; Retrospective Studies; Tension-Type Headache; Time Factors; Topiramate; Vasodilator Agents; Verapamil

2009
Persistence with migraine prophylactic treatment and acute migraine medication utilization in the managed care setting.
    Clinical therapeutics, 2008, Volume: 30, Issue:12

    Topics: Adult; Age Factors; Amitriptyline; Cohort Studies; Databases, Factual; Dose-Response Relationship, Drug; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Female; Fructose; Humans; Kaplan-Meier Estimate; Male; Managed Care Programs; Medication Adherence; Middle Aged; Migraine Disorders; Proportional Hazards Models; Propranolol; Retrospective Studies; Sex Factors; Time Factors; Timolol; Topiramate; Valproic Acid

2008
The efficacy of withdrawal therapy in subjects with chronic daily headache and medication overuse following prophylaxis with topiramate and amitriptyline.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2010, Volume: 31 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics, Non-Narcotic; Chronic Disease; Female; Fructose; Headache Disorders; Humans; Male; Middle Aged; Patient Selection; Topiramate; Treatment Outcome

2010
[Chronic migraine: not well known but not rare!].
    MMW Fortschritte der Medizin, 2011, Mar-24, Volume: 153, Issue:12

    Topics: Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Chronic Disease; Female; Fructose; Humans; Male; Migraine Disorders; Risk Factors; Topiramate; Tryptamines; Valproic Acid

2011
Cost-effectiveness analysis of interventions for migraine in four low- and middle-income countries.
    The journal of headache and pain, 2015, Feb-18, Volume: 16

    Topics: Amitriptyline; China; Cost-Benefit Analysis; Fructose; Humans; Income; India; Medication Adherence; Migraine Disorders; Models, Economic; Propranolol; Russia; Self Care; Topiramate; Treatment Outcome; Zambia

2015
Association of MDR1, CYP2D6, and CYP2C19 gene polymorphisms with prophylactic migraine treatment response.
    Journal of the neurological sciences, 2016, Jul-15, Volume: 366

    Topics: Adult; Amitriptyline; ATP Binding Cassette Transporter, Subfamily B; Central Nervous System Agents; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Drug Resistance; Female; Fructose; Gene Frequency; Genetic Association Studies; Humans; Male; Migraine Disorders; Polymorphism, Genetic; Propranolol; Risk Factors; Topiramate; Treatment Outcome; Valproic Acid

2016
Factors Influencing Response to Pharmacologic Treatment of Migraine in a Pediatric Headache Clinic.
    Headache, 2016, Volume: 56, Issue:7

    Topics: Adolescent; Age Factors; Amitriptyline; Central Nervous System Agents; Child; Child, Preschool; Cohort Studies; Comorbidity; Female; Follow-Up Studies; Fructose; Humans; Male; Mental Disorders; Migraine Disorders; Propranolol; Puberty; Tertiary Care Centers; Topiramate; Treatment Outcome

2016
Amitriptyline and topiramate are no better than placebo for childhood migraine.
    Archives of disease in childhood. Education and practice edition, 2017, Volume: 102, Issue:6

    Topics: Amitriptyline; Double-Blind Method; Fructose; Humans; Migraine Disorders; Topiramate; Treatment Outcome

2017
Amitriptyline and topiramate do not demonstrate benefit in pediatric migraine.
    The Journal of pediatrics, 2017, Volume: 186

    Topics: Amitriptyline; Child; Fructose; Humans; Migraine Disorders; Topiramate

2017
Screen time associated with adolescent obesity and obesity risk factors.
    The Journal of pediatrics, 2017, Volume: 186

    Topics: Adolescent; Amitriptyline; Child; Humans; Migraine Disorders; Obesity; Pediatric Obesity; Risk Factors; Screen Time; Sedentary Behavior; Topiramate

2017
[Drugs news].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2017, Volume: 24, Issue:8

    Topics: Adolescent; Adult; Age Factors; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Child; Drug Industry; Duodenal Ulcer; Female; France; Gastroesophageal Reflux; Humans; Male; Migraine Disorders; Pharmacovigilance; Phenytoin; Plasma Substitutes; Polygeline; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Stomach Ulcer; Topiramate

2017
PURL: Treating migraines: It's different for kids.
    The Journal of family practice, 2018, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Amitriptyline; Child; Humans; Migraine Disorders; Topiramate

2018
Survey of Child Neurologists on Management of Pediatric Post-traumatic Headache.
    Journal of child neurology, 2019, Volume: 34, Issue:12

    Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Health Care Surveys; Humans; Neurologists; Post-Concussion Syndrome; Post-Traumatic Headache; Topiramate

2019
Analysis of the effectiveness of the prophylaxis of vestibular migraine depending on the diagnostic category and the prescribed drug.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2020, Volume: 277, Issue:4

    Topics: Acetazolamide; Amitriptyline; Analgesics; Central Nervous System Agents; Flunarizine; Humans; Migraine Disorders; Propranolol; Prospective Studies; Topiramate; Vertigo; Vestibular Diseases

2020
Developing an Artificial Intelligence-Guided Signal Detection in the Food and Drug Administration Adverse Event Reporting System (FAERS): A Proof-of-Concept Study Using Galcanezumab and Simulated Data.
    Drug safety, 2023, Volume: 46, Issue:8

    Topics: Adverse Drug Reaction Reporting Systems; Amitriptyline; Artificial Intelligence; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Topiramate; United States; United States Food and Drug Administration

2023